Chromodomain helicase/adenosine triphosphatase DNA binding protein 1-like (CHD1L) gene suppresses the nucleus-to-mitochondria translocation of Nur77 to sustain hepatocellular carcinoma cell survival

Hepatology

Volumn 50, Issue 1, 2009, Pages 122-129

  Chen, Leilei ^a   Hu, Liang ^a   Chan, Tim Hon Man ^a   Tsao, George Sai Wah ^a   Xie, Dan ^b   Huo, Ke Ke ^c   Fu, Li ^a   Ma, Stephanie ^a   Zheng, Bo Jian ^a   Guan, Xin Yuan ^a,b  

^a UNIVERSITY OF HONG KONG   (Hong Kong)

^b SUN YAT SEN UNIVERSITY CANCER CENTER   (China)

^c FUDAN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROTEIN; CHROMODOMAIN HELICASE ADENOSINE TRIPHOSPHATASE DNA BINDING PROTEIN 1 LIKE PROTEIN; CYTOCHROME C; NUCLEAR RECEPTOR NUR77; UNCLASSIFIED DRUG; ADENOSINE TRIPHOSPHATASE; CHD1 PROTEIN, HUMAN; DNA BINDING PROTEIN; HELICASE; STEROID RECEPTOR;

APOPTOSIS; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL NUCLEUS; CELL SURVIVAL; CONTROLLED STUDY; GENE FUNCTION; HUMAN; HUMAN CELL; LIVER CELL CARCINOMA; MITOCHONDRION; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; PROTEIN SECRETION; PROTEIN TRANSPORT; ENZYMOLOGY; GENETICS; LIVER TUMOR; METABOLISM; PATHOLOGY; PHYSIOLOGY;

ADENOSINE TRIPHOSPHATASES; CARCINOMA, HEPATOCELLULAR; CELL NUCLEUS; CELL SURVIVAL; DNA HELICASES; DNA-BINDING PROTEINS; HUMANS; LIVER NEOPLASMS; MITOCHONDRIA; PROTEIN TRANSPORT; RECEPTORS, STEROID;

EID: 67651174841     PISSN: 02709139     EISSN: None     Source Type: Journal    
DOI: 10.1002/hep.22933     Document Type: Article

References (27)

1. Parkin DM, Bray F, Ferlay J, Pisani P. Global cancer statistics, 2002. CA Cancer J Clin 2005;55:74-108.
2. Marchio A, Meddeb M, Pineau P, Danglot G, Tiollais P, Bernheim A, et al. Recurrent chromosomal abnormalities in hepatocellular carcinoma detected by comparative genomic hybridization. Genes Chromosomes Cancer 1997;18:59-65. (Pubitemid 27020257)
3. Kusano N, Shiraishi K, Kubo K, Oga A, Okita K, Sasaki K. Genetic aberrations detected by comparative genomic hybridization in hepatocellular carcinomas: their relationship to clinicopathological features. HEPATOLOGY 1999;29:1858-1862. (Pubitemid 29247061)
4. Wong N, Lai P, Lee SW, Fan S, Pang E, Liew CT, et al. Assessment of genetic changes in hepatocellular carcinoma by comparative genomic hybridization analysis: relationship to disease stage, tumor size, and cirrhosis. Am J Pathol 1999;154:37-43. (Pubitemid 29031609)
5. Guan XY, Fang Y, Sham JS, Kwong DL, Zhang Y, Liang Q, et al. Recurrent chromosome alterations in hepatocellular carcinoma detected by comparative genomic hybridization. Genes Chromosomes Cancer 2000;29: 110-116. (Pubitemid 30679669)
6. Ma NF, Hu L, Fung JM, Xie D, Zheng BJ, Chen L, et al. Isolation and characterization of a novel oncogene, amplified in liver cancer 1, within a commonly amplified region at 1q21 in hepatocellular carcinoma. HEPATOLOGY 2008;47:503-510. (Pubitemid 351280718)
7. Mangelsdorf DJ, Evans RM. The RXR heterodimers and orphan receptors. Cell 1995;83:841-850
8. Hazel TG, Nathans D, Lau LF. A gene inducible by serum growth factors encodes a member of the steroid and thyroid hormone receptor superfamily. Proc Natl Acad Sci U S A 1988;85:8444-8448. (Pubitemid 19024988)
9. Winoto A, Littman DR. Nuclear hormone receptors in T lymphocytes. Cell 2002;109(Suppl):S57-S66.
10. Moll UM, Marchenko N, Zhang XK. p53 and Nur77/TR3-transcription factors that directly target mitochondria for cell death induction. Oncogene 2006;25:4725-4743. (Pubitemid 44187622)
11. Li P, Nijhawan D, Budihardjo I, Srinivasula SM, Ahmad M, Alnemri ES, et al. Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade. Cell 1997;91:479-489. (Pubitemid 27508237)
12. Li H, Kolluri SK, Gu J, Dawson MI, Cao X, Hobbs PD, et al. Cytochrome c release and apoptosis induced by mitochondrial targeting of nuclear orphan receptor TR3. Science 2000;289:1159-1164. (Pubitemid 30650723)
13. Lin B, Kolluri SK, Lin F, Liu W, Han YH, Cao X, et al. Conversion of Bcl-2 from protector to killer by interaction with nuclear orphan receptor Nur77/TR3. Cell 2004;116:527-540. (Pubitemid 38264430)
14. Li Y, Lin B, Agadir A, Liu R, Dawson MI, Reed JC, et al. Molecular determinants of AHPN (CD437)-induced growth arrest and apoptosis in human lung cancer cell lines. Mol Cell Biol 1998;18:4719-4731. (Pubitemid 28343057)
15. Wu Q, Liu S, Ye XF, Huang ZW, Su WJ. Dual roles of Nur77 in selective regulation of apoptosis and cell cycle by TPA and ATRA in gastric cancer cells. Carcinogenesis 2002;23:1583-1592. (Pubitemid 35214942)
16. Holmes WF, Soprano DR, Soprano KJ. Elucidation of molecular events mediating induction of apoptosis by synthetic retinoids using a CD437- resistant ovarian carcinoma cell line. J Biol Chem 2002;277:45408-45419.
17. Wilson AJ, Arango D, Mariadason JM, Heerdt BG, Augenlicht LH. TR3/ Nur77 in colon cancer cell apoptosis. Cancer Res 2003;63:5401-5407. (Pubitemid 37139857)
18. Hu L, Lau SH, Tzang CH, Wen JM, Wang W, Xie D, et al. Association of Vimentin overexpression and hepatocellular carcinoma metastasis. Oncogene 2004;23:298-302. (Pubitemid 38142264)
19. Stennicke HR, Deveraux QL, Humke EW, Reed JC, Dixit VM, Salvesen GS. Caspase-9 can be activated without proteolytic processing. J Biol Chem 1999;274:8359-8362.
20. Rodriguez J, Lazebnik Y. Caspase-9 and APAF-1 form an active holoenzyme. Genes Dev 1999;13:3179-3184. (Pubitemid 30030439)
21. Maddika S, Booy EP, Johar D, Gibson SB, Ghavami S, Los M. Cancer-specific toxicity of apoptin is independent of death receptors but involves the loss of mitochondrial membrane potential and the release of mitochondrial cell-death mediators by a Nur77-dependent pathway. J Cell Sci 2005; 118:4485-4493. (Pubitemid 41556346)
22. Lee JM, Lee KH, Weidner M, Osborne BA, Hayward SD. Epstein-Barr virus EBNA2 blocks Nur77-mediated apoptosis. Proc Natl Acad Sci U S A 2002;99:11878-11883. (Pubitemid 34994492)
23. Holmes WF, Soprano DR, Soprano KJ. Comparison of the mechanism of induction of apoptosis in ovarian carcinoma cells by the conformationally restricted synthetic retinoids CD437 and 4-HPR. J Cell Biochem 2003; 89:262-278.
24. Holmes WF, Soprano DR, Soprano KJ. Synthetic retinoids as inducers of apoptosis in ovarian carcinoma cell lines. J Cell Physiol 2004;199:317-329. (Pubitemid 38580429)
25. Kolluri SK, Bruey-Sedano N, Cao X, Lin B, Lin F, Han YH, et al. Mitogenic effect of orphan receptor TR3 and its regulation by MEKK1 in lung cancer cells. Mol Cell Biol 2003;23:8651-8667. (Pubitemid 37433369)
26. Reed JC. Mechanisms of apoptosis avoidance in cancer. Curr Opin Oncol 1999;11:68-75.
27. Fabregat I, Roncero C, Fernandez M. Survival and apoptosis: a dysregulated balance in liver cancer. Liver Int 2007;27:155-162. (Pubitemid 46680718)