메뉴 건너뛰기




Volumn 91, Issue 3, 2000, Pages 287-292

PTEN/MMAC1 mutation and frequent loss of heterozygosity identified in chromosome 10q in a subset of hepatocellular carcinomas

Author keywords

Hepatocellular carcinoma; LOH; Microsatellite marker; PTEN MMAC 1

Indexed keywords

DINUCLEOTIDE; MICROSATELLITE DNA;

EID: 0034079163     PISSN: 09105050     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1349-7006.2000.tb00943.x     Document Type: Article
Times cited : (52)

References (41)
  • 1
    • 0026041836 scopus 로고
    • Aberrations of the tumor suppressor p53 and retinoblastoma genes in human hepatocellular carcinomas
    • Murakami, Y., Hayashi, K., Hirohashi, S. and Sekiya, T. Aberrations of the tumor suppressor p53 and retinoblastoma genes in human hepatocellular carcinomas. Cancer Res., 51, 5520-5525 (1991).
    • (1991) Cancer Res. , vol.51 , pp. 5520-5525
    • Murakami, Y.1    Hayashi, K.2    Hirohashi, S.3    Sekiya, T.4
  • 2
    • 0028023861 scopus 로고
    • Deletions of chromosome 13q, mutations in retinoblastoma 1, and retinoblastoma protein state in human hepatocellular carcinoma
    • Zhang, X., Xu, H. J., Murakami, Y., Sachse, R., Yashima, K., Hirohashi, S., Hu, S. X., Benedict, W. F. and Sekiya, T. Deletions of chromosome 13q, mutations in retinoblastoma 1, and retinoblastoma protein state in human hepatocellular carcinoma. Cancer Res., 54, 4177-4182 (1994).
    • (1994) Cancer Res. , vol.54 , pp. 4177-4182
    • Zhang, X.1    Xu, H.J.2    Murakami, Y.3    Sachse, R.4    Yashima, K.5    Hirohashi, S.6    Hu, S.X.7    Benedict, W.F.8    Sekiya, T.9
  • 3
    • 0028111570 scopus 로고
    • Frequent genetic alterations at the distal region of chromosome 1p in human hepatocellular carcinomas
    • Yeh, S. H., Chen, P. J., Chen, H. L., Lai, M. Y., Wang, C. C. and Chen, D. S. Frequent genetic alterations at the distal region of chromosome 1p in human hepatocellular carcinomas. Cancer Res., 54, 4188-4192 (1994).
    • (1994) Cancer Res. , vol.54 , pp. 4188-4192
    • Yeh, S.H.1    Chen, P.J.2    Chen, H.L.3    Lai, M.Y.4    Wang, C.C.5    Chen, D.S.6
  • 4
    • 0024263645 scopus 로고
    • Deletions in human chromosome arms 11p and 13q in primary hepatocellular carcinomas
    • Wang, H. P. and Rogler, C. E. Deletions in human chromosome arms 11p and 13q in primary hepatocellular carcinomas. Cytogenet. Cell Genet., 48, 72-78 (1988).
    • (1988) Cytogenet. Cell Genet. , vol.48 , pp. 72-78
    • Wang, H.P.1    Rogler, C.E.2
  • 6
    • 0027276536 scopus 로고
    • Frequent loss of heterozygosity on chromosome 22 in hepatocellular carcinoma
    • Takahashi, K., Kudo, J., Ishibashi, H., Hirata, Y. and Niho, Y. Frequent loss of heterozygosity on chromosome 22 in hepatocellular carcinoma. Hepatology, 17, 794-799 (1993).
    • (1993) Hepatology , vol.17 , pp. 794-799
    • Takahashi, K.1    Kudo, J.2    Ishibashi, H.3    Hirata, Y.4    Niho, Y.5
  • 7
    • 0030849123 scopus 로고    scopus 로고
    • Comprehensive allelotyping of human hepatocellular carcinoma
    • Nagai, H., Pineau, P., Tiollais, P., Buendia, M. A. and Dejean, A. Comprehensive allelotyping of human hepatocellular carcinoma. Oncogene, 14, 2927-2933 (1997).
    • (1997) Oncogene , vol.14 , pp. 2927-2933
    • Nagai, H.1    Pineau, P.2    Tiollais, P.3    Buendia, M.A.4    Dejean, A.5
  • 8
    • 0031853180 scopus 로고    scopus 로고
    • Deletion mapping of chromosome 4q in hepatocellular carcinoma
    • Piao, Z., Park, C., Park, J. H. and Kim, H. Deletion mapping of chromosome 4q in hepatocellular carcinoma. Int. J. Cancer, 79, 356-360 (1998).
    • (1998) Int. J. Cancer , vol.79 , pp. 356-360
    • Piao, Z.1    Park, C.2    Park, J.H.3    Kim, H.4
  • 9
    • 0026328438 scopus 로고
    • Loss of constitutional heterozygosity on chromosome 5q in hepatocellular carcinoma without cirrhosis
    • Ding, S. F., Habib, N. A., Dooley, J., Wood, C., Bowles, L. and Delhanty, J. D. Loss of constitutional heterozygosity on chromosome 5q in hepatocellular carcinoma without cirrhosis. Br. J. Cancer, 64, 1083-1087 (1991).
    • (1991) Br. J. Cancer , vol.64 , pp. 1083-1087
    • Ding, S.F.1    Habib, N.A.2    Dooley, J.3    Wood, C.4    Bowles, L.5    Delhanty, J.D.6
  • 10
    • 0024801490 scopus 로고
    • Low incidence of point mutation of c-Ki-ras and N-ras oncogenes in human hepatocellular carcinoma
    • Tsuda, H., Hirohashi, S., Shimosato, Y., Ino, Y., Yoshida, T. and Terada, M. Low incidence of point mutation of c-Ki-ras and N-ras oncogenes in human hepatocellular carcinoma. Jpn. J. Cancer Res., 80, 196-199 (1989).
    • (1989) Jpn. J. Cancer Res. , vol.80 , pp. 196-199
    • Tsuda, H.1    Hirohashi, S.2    Shimosato, Y.3    Ino, Y.4    Yoshida, T.5    Terada, M.6
  • 11
    • 0032525836 scopus 로고    scopus 로고
    • Activation of the beta-catenin gene in primary hepatocellular carcinomas by somatic alterations involving exon 3
    • Miyoshi, Y., Iwao, K., Nagasawa, Y., Aihara, T., Sasaki, Y., Imaoka, S., Murata, M., Shimano, T. and Nakamura, Y. Activation of the beta-catenin gene in primary hepatocellular carcinomas by somatic alterations involving exon 3. Cancer Res., 58, 2524-2527 (1998).
    • (1998) Cancer Res. , vol.58 , pp. 2524-2527
    • Miyoshi, Y.1    Iwao, K.2    Nagasawa, Y.3    Aihara, T.4    Sasaki, Y.5    Imaoka, S.6    Murata, M.7    Shimano, T.8    Nakamura, Y.9
  • 12
    • 0032581534 scopus 로고    scopus 로고
    • Distinct regions of allelic imbalance on chromosome 10q22-q26 in squamous cell carcinomas of the lung
    • Petersen, S., Rudolf, J., Bockmuhl, U., Gellert, K., Wolf, G., Dietel, M. and Petersen, I. Distinct regions of allelic imbalance on chromosome 10q22-q26 in squamous cell carcinomas of the lung. Oncogene, 17, 449-454 (1998).
    • (1998) Oncogene , vol.17 , pp. 449-454
    • Petersen, S.1    Rudolf, J.2    Bockmuhl, U.3    Gellert, K.4    Wolf, G.5    Dietel, M.6    Petersen, I.7
  • 13
    • 0028841184 scopus 로고
    • Allelic losses on chromosomes 14, 10, and 1 in atypical and malignant meningiomas: A genetic model of meningioma progression
    • Simon, M., von, Deimling, A., Larson, J. J., Wellenreuther, R., Kaskel, P., Waha, A., Warnick, R. E., Tew, J. J. and Menon, A. G. Allelic losses on chromosomes 14, 10, and 1 in atypical and malignant meningiomas: a genetic model of meningioma progression. Cancer Res., 55, 4696-4701 (1995).
    • (1995) Cancer Res. , vol.55 , pp. 4696-4701
    • Simon, M.1    Von Deimling, A.2    Larson, J.J.3    Wellenreuther, R.4    Kaskel, P.5    Waha, A.6    Warnick, R.E.7    Tew, J.J.8    Menon, A.G.9
  • 16
    • 0030062814 scopus 로고    scopus 로고
    • Deletions of the long arm of chromosome 10 in progression of follicular thyroid tumors
    • Zedenius, J., Wallin, G., Svensson, A., Bovee, J., Hoog, A., Backdahl, M. and Larsson, C. Deletions of the long arm of chromosome 10 in progression of follicular thyroid tumors. Hum. Genet., 97, 299-303 (1996).
    • (1996) Hum. Genet. , vol.97 , pp. 299-303
    • Zedenius, J.1    Wallin, G.2    Svensson, A.3    Bovee, J.4    Hoog, A.5    Backdahl, M.6    Larsson, C.7
  • 17
    • 0032500108 scopus 로고    scopus 로고
    • Allelic loss of chromosome 10q23 is associated with tumor progression in breast carcinomas
    • Bose, S., Wang, S. I., Terry, M. B., Hibshoosh, H. and Parsons, R. Allelic loss of chromosome 10q23 is associated with tumor progression in breast carcinomas. Oncogene, 17, 123-127 (1998).
    • (1998) Oncogene , vol.17 , pp. 123-127
    • Bose, S.1    Wang, S.I.2    Terry, M.B.3    Hibshoosh, H.4    Parsons, R.5
  • 18
    • 8544237725 scopus 로고    scopus 로고
    • Frequent loss of heterozygosity on chromosome 10q in muscle-invasive transitional cell carcinomas of the bladder
    • Cappellen, D., Gil, D. D. M. S., Chopin, D., Thiery, J. P. and Radvanyi, F. Frequent loss of heterozygosity on chromosome 10q in muscle-invasive transitional cell carcinomas of the bladder. Oncogene, 14, 3059-3066 (1997).
    • (1997) Oncogene , vol.14 , pp. 3059-3066
    • Cappellen, D.1    Gil, D.D.M.S.2    Chopin, D.3    Thiery, J.P.4    Radvanyi, F.5
  • 19
    • 0032473921 scopus 로고    scopus 로고
    • Analysis of PTEN and the 10q23 region in primary prostate carcinomas
    • Feilotter, H. F., Nagai, M. A., Boag, A. H., Eng, C. and Mulligan, L. M. Analysis of PTEN and the 10q23 region in primary prostate carcinomas. Oncogene, 16, 1743-1748 (1998).
    • (1998) Oncogene , vol.16 , pp. 1743-1748
    • Feilotter, H.F.1    Nagai, M.A.2    Boag, A.H.3    Eng, C.4    Mulligan, L.M.5
  • 21
    • 0027958595 scopus 로고
    • Allelotype of uterine cancer by analysis of RFLP and microsatellite polymorphisms: Frequent loss of heterozygosity on chromosome, arms 3p, 9q. 10q, and 17p
    • Jones, M. H., Koi, S., Fujimoto, I., Hasumi, K., Kato, K. and Nakamura, Y. Allelotype of uterine cancer by analysis of RFLP and microsatellite polymorphisms: frequent loss of heterozygosity on chromosome, arms 3p, 9q. 10q, and 17p. Genes Chromosom. Cancer, 9, 119-123 (1994).
    • (1994) Genes Chromosom. Cancer , vol.9 , pp. 119-123
    • Jones, M.H.1    Koi, S.2    Fujimoto, I.3    Hasumi, K.4    Kato, K.5    Nakamura, Y.6
  • 25
    • 0032576872 scopus 로고    scopus 로고
    • PTEN/MMAC1 mutations in primary glioblastomas and short-term cultures of malignant gliomas
    • Chiariello, E., Roz, L., Albarosa, R., Magnani, I. and Finocchiaro, G. PTEN/MMAC1 mutations in primary glioblastomas and short-term cultures of malignant gliomas. Oncogene, 16, 541-545 (1998).
    • (1998) Oncogene , vol.16 , pp. 541-545
    • Chiariello, E.1    Roz, L.2    Albarosa, R.3    Magnani, I.4    Finocchiaro, G.5
  • 26
    • 0031596872 scopus 로고    scopus 로고
    • Inactivation of the PTEN/MMAC1/TEP1 gene in human lung cancers
    • Kohno, T., Takahashi, M., Manda, R. and Yokota, J. Inactivation of the PTEN/MMAC1/TEP1 gene in human lung cancers. Genes Chromosom. Cancer, 22, 152-156 (1998).
    • (1998) Genes Chromosom. Cancer , vol.22 , pp. 152-156
    • Kohno, T.1    Takahashi, M.2    Manda, R.3    Yokota, J.4
  • 34
    • 0025250745 scopus 로고
    • Allelotype of breast cancer: Cumulative allele losses promote tumor progression in primary breast cancer
    • Sato, T., Tanigami, A., Yamakawa, K., Akiyama, F., Kasumi, F., Sakamoto, G. and Nakamura, Y. Allelotype of breast cancer: cumulative allele losses promote tumor progression in primary breast cancer. Cancer Res., 50, 7184-7189 (1990).
    • (1990) Cancer Res. , vol.50 , pp. 7184-7189
    • Sato, T.1    Tanigami, A.2    Yamakawa, K.3    Akiyama, F.4    Kasumi, F.5    Sakamoto, G.6    Nakamura, Y.7
  • 36
    • 0031964511 scopus 로고    scopus 로고
    • Interfocal heterogeneity of PTEN/MMAC1 gene alterations in multiple metastatic prostate cancer tissues
    • Suzuki, H., Freije, D., Nusskern, D. R., Okami, K., Cairns, P., Sidransky, D., Isaacs, W. B. and Bova, G. S. Interfocal heterogeneity of PTEN/MMAC1 gene alterations in multiple metastatic prostate cancer tissues. Cancer Res., 58, 204-209 (1998).
    • (1998) Cancer Res. , vol.58 , pp. 204-209
    • Suzuki, H.1    Freije, D.2    Nusskern, D.R.3    Okami, K.4    Cairns, P.5    Sidransky, D.6    Isaacs, W.B.7    Bova, G.S.8
  • 37
    • 0032566064 scopus 로고    scopus 로고
    • Somatic deletion mapping on chromosome 10 and sequence analysis of PTEN/MMAC1 point to the 10q25-26 region as the primary target in low-grade and high-grade gliotnas
    • Maier, D., Zhang, Z., Taylor, E., Hamou, M. F., Gratzl, O., Van, M. E., Scott, R. J. and Merlo, A. Somatic deletion mapping on chromosome 10 and sequence analysis of PTEN/MMAC1 point to the 10q25-26 region as the primary target in low-grade and high-grade gliotnas. Oncogene, 16, 3331-3335 (1998).
    • (1998) Oncogene , vol.16 , pp. 3331-3335
    • Maier, D.1    Zhang, Z.2    Taylor, E.3    Hamou, M.F.4    Gratzl, O.5    Van, M.E.6    Scott, R.J.7    Merlo, A.8
  • 38
    • 0032577699 scopus 로고    scopus 로고
    • The tumor suppressor, PTEN/MMAC1. Dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate
    • Maehama, T. and Dixon, J. E. The tumor suppressor, PTEN/MMAC1. dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate. J. Biol. Chem., 273, 13375-13378 (1998).
    • (1998) J. Biol. Chem. , vol.273 , pp. 13375-13378
    • Maehama, T.1    Dixon, J.E.2
  • 40
    • 0032486198 scopus 로고    scopus 로고
    • Inhibition of cell migration, spreading, and focal adhesions by tumor suppressor PTEN
    • Tumura, M., Gu, J., Matsumoto, K., Aota, S., Parsons, R. and Yamada, K. M. Inhibition of cell migration, spreading, and focal adhesions by tumor suppressor PTEN. Science, 280, 1614-1617 (1998).
    • (1998) Science , vol.280 , pp. 1614-1617
    • Tumura, M.1    Gu, J.2    Matsumoto, K.3    Aota, S.4    Parsons, R.5    Yamada, K.M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.