SOCS-1, a negative regulator of the JAK/STAT pathway, is silenced by methylation in human hepatocellular carcinoma and shows growth-suppression activity

Nature Genetics

Volumn 28, Issue 1, 2001, Pages 29-35

  Yoshikawa, Hirohide ^a   Matsubara, Kenichi ^b   Qian, Geng Sun ^c   Jackson, Peta ^d   Groopman, John D ^d   Manning, Jasper E ^a   Harris, Curtis C ^e   Herman, James G ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NARA INSTITUTE OF SCIENCE AND TECHNOLOGY   (Japan)

^c SHANGHAI CANCER INSTITUTE   (China)

^d JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

^e NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

JANUS KINASE; N BENZYL 2 CYANO 3 (3,4 DIHYDROXYPHENYL)ACRYLAMIDE; PROTEIN; PROTEIN TYROSINE KINASE INHIBITOR; STAT PROTEIN; STAT3 PROTEIN; SUPPRESSOR OF CYTOKINE SIGNALING 1; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CANCER INHIBITION; CELL GROWTH; GENE THERAPY; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; LIVER CELL CARCINOMA; METHYLATION; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

JANUS;

EID: 0035042611     PISSN: 10614036     EISSN: None     Source Type: Journal    
DOI: 10.1038/88225     Document Type: Article

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