Mapping of a minimal deleted region in human hepatocellular carcinoma to 1p36.13-p36.23 and mutational analysis of the RIZ (PRDM2) gene localized to the region

Genes Chromosomes and Cancer

Volumn 28, Issue 3, 2000, Pages 269-275

  Fang, Wei ^a   Piao, Zhe ^a   Simon, Daniela ^b   Sheu, Jin Chuan ^c   Huang, Shi ^a  

^a BURNHAM INSTITUTE   (United States)

^b DREXEL UNIVERSITY COLLEGE OF MEDICINE   (United States)

^c NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

GENE PRODUCT; RIZ PROTEIN; UNCLASSIFIED DRUG; ZINC FINGER PROTEIN;

ALLELE; ARTICLE; CHROMOSOME 1P; CHROMOSOME MAP; FEMALE; GENE INACTIVATION; GENE MUTATION; HETEROZYGOSITY LOSS; HUMAN; HUMAN TISSUE; LIVER CELL CARCINOMA; MAJOR CLINICAL STUDY; MALE; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DOMAIN; SINGLE STRAND CONFORMATION POLYMORPHISM; TUMOR SUPPRESSOR GENE;

ALLELES; CARCINOMA, HEPATOCELLULAR; CHROMOSOME DELETION; CHROMOSOME MAPPING; CHROMOSOMES, HUMAN, PAIR 1; DNA MUTATIONAL ANALYSIS; DNA, NEOPLASM; DNA-BINDING PROTEINS; FEMALE; HUMANS; LIVER NEOPLASMS; LOSS OF HETEROZYGOSITY; MALE; NUCLEAR PROTEINS; POLYMORPHISM, SINGLE-STRANDED CONFORMATIONAL; TRANSCRIPTION FACTORS; ZINC FINGERS;

MUS MUSCULUS;

EID: 0034083469     PISSN: 10452257     EISSN: None     Source Type: Journal    
DOI: 10.1002/1098-2264(200007)28:3<269::AID-GCC4>3.0.CO;2-K     Document Type: Article

References (40)

1. Bardi G, Pandis N, Fenger C, Kronborg O, Bomme L, Heim S. 1993. Deletion of 1p36 as a primary chromosomal aberration in intestinal tumorigenesis. Cancer Res 53:1895-1898.
2. Bieche I, Khodja A, Lidereau R. 1999. Deletion mapping of chromosomal region Ip32-pter in primary breast cancer. Genes Chromosomes Cancer 24:255-263.
3. Buyse IM, Shao G, Huang S. 1995. The retinoblastoma protein binds to RIZ, a zinc finger protein that shares an epitope with the adenovirus E1A protein. Proc Natl Acad Sci USA 92:4467-4471.
4. Cigudosa JC, Parsa NZ, Louie DC, Filippa DA, Jhanwar SC, Johansson B, Mitelman F, Chaganti RS. 1999. Cytogenetic analysis of 363 consecutively ascertained diffuse large B-cell lymphomas. Genes Chromosomes Cancer 25:123-133.
5. Dave BJ, Pickering DL, Hess MM, Weisenburger DD, Armitage JO, Sanger WG. 1999. Deletion of cell division cycle 2-like 1 gene locus on 1p36 in non-Hodgkin lymphoma. Cancer Genet Cytogenet 108:120-126.
6. Dracopoli NC, Harnett P, Bale SJ, Stanger BZ, Tucker MA, Housman DE, Kefford RF. 1989. Loss of alleles from the distal short arm of chromosome 1 occurs late in melanoma tumor progression. Proc Natl Acad Sci USA 86:4614-4618.
7. Fero ML, Randel E, Gurley KE, Roberts JM, Kemp CJ. 1998. The murine gene p27Kip1 is haplo-insufficient for tumour suppression. Nature 396:177-180.
8. Fong CT, White PS, Peterson K, Sapienza C, Cavenee WK, Kern SE, Vogelstein B, Cantor AB, Look AT, Brodeur GM. 1992. Loss of heterozygosity for chromosomes 1 or 14 defines subsets of advanced neuroblastomas. Cancer Res 52:1780-1785.
9. Genuardi M, Tsihira H, Anderson DE, Saunders GF. 1989. Distal deletion of chromosome 1p in ductal carcinoma of the breast. Am J Hum Genet 45:73-82.
10. Gibbs M, Stanford JL, McIndoe RA, Jarvik GP, Kolb S, Goode EL, Chakrabarti L, Schuster EF, Buckley VA, Miller EL, Brandzel S, Li S, Hood L, Ostrander EA. 1999. Evidence for a rare prostate cancer-susceptibility locus at chromosome 1p36. Am J Hum Genet 64:776-787.
11. Greenblatt MS, Bennett WP, Hollstein M, Harris CC. 1994. Mutations in the p53 tumor suppressor gene: clues to cancer etiology and molecular pathogenesis. Cancer Res 54:4855-4878.
12. Hammond C, Jeffers L, Carr BI, Simon D. 1999. Multiple genetic alterations, 4q28, a new suppressor region, and potential gender differences in human hepatocellular carcinoma. Hepatology 29: 1479-1485.
13. Harnett PR, Kearsley JH, Hayward NK, Dracopoli, NC, Kefford RF. 1991. Loss of allelic heterozygosity on distal chromosome 1p in Merkel cell carcinoma. A marker of neural crest origins? Cancer Genet Cytogenet 54:109-113.
14. He L, Yu JX, Liu L, Buyse IM, Wang MS, Yang QC, Nakagawara A, Brodeur GM, Shi YE, Huang S. 1998. RIZ1, but not the alternative RIZ2 product of the same gene, is underexpressed in breast cancer, and forced RIZ1 expression causes G2-M cell cycle arrest or apoptosis. Cancer Res 58:4238-4244.
15. Hoggard N, Brintnell B, Howell A, Weissenbach J, Varley J. 1995. Allelic imbalance on chromosome 1 in human breast cancer. II. Microsatellite repeat analysis. Genes Chromosomes Cancer 12: 24-31.
16. Huang S. 1994. Blimp-1 is the murine homolog of the human transcriptional repressor PRDI-BF1. Cell 78:9.
17. Huang S. 1999. The retinoblastoma protein-interacting zinc finger gene RIZ in 1p36-linked cancers. Front Biosci 4:D528-D532.
18. Huang S, Shao G, Liu L. 1998. The PR domain of the Rb-binding zinc finger protein RIZ1 is a protein binding interface and is related to the SET domain functioning in chromatin-mediated gene expression. J Biol Chem 273:15933-15940.
19. Jensen SJ, Sulman EP, Maris JM, Matise TC, Vojta PJ, Barrett JC, Brodeur GM, White PS. 1997. An integrated transcript map of human chromosome 1p35-36. Genomics 42:126-136.
20. Jiang GL, Huang S. 1999. The yin-yang of PR-domain family genes in tumorigenesis. Histol Histopathol 15:109-117.
21. Jiang GL, Liu L, Buyse IM, Simon D, Huang S. 1999. Decreased RIZ1 expression but not RIZ2 in hepatoma and suppression of hepatoma tumorigenicity by RIZ1. Int J Cancer 83:541-547.
22. Juneja S, Lukeis R, Tan L, Cooper I, Szelag G, Parkin JD, Ironside P, Garson OM. 1990. Cytogenetic analysis of 147 cases of non-Hodgkin's lymphoma: non-random chromosomal abnormalities and histological correlations. Br J Haematol 76:231-7.
23. Kuroki T, Fujiwara Y, Tsuchiya E, Nakamori S, Imaoka S, Kanematsu T, Nakamura Y. 1995. Accumulation of genetic changes during development and progression of hepatoccllular carcinoma: loss of heterozygosity of chromosome arm 1p occurs at an early stage of hepatocarcinogenesis. Genes Chromosomes Cancer 13: 163-167.
24. Ladanyi M, Parsa NZ, Offit K, Wachtel MS, Filippa DA, Jhanwar SC. 1991. Clonal cytogenetic abnormalities in Hodgkin's disease. Genes Chromosomes Cancer 3:294-299.
25. Lin YW, Sheu JC, Huang GT, Lee HS, Chen CH, Wang JT, Lee PH, Lu FJ. 1999. Chromosomal abnormality in hepatocellular carcinoma by comparative genomic hybridization in Taiwan. Int J Cancer 35:652-658.
26. Liu L, Shao G, Steele-Perkins G, Huang S. 1997. The retinoblastoma interacting zinc finger gene RIZ produces a PR domain lacking product through an internal promoter. J Biol Chem 272: 2984-2991.
27. Loupart ML, Armour J, Walker R, Adams S, Brammar W, Varley J. 1995. Allelic imbalance on chromosome 1 in human breast cancer. I. Minisatellite and RFLP analysis. Genes Chromosomes Cancer 12:16-23.
28. Mori N, Morosetti R, Spira S, Lee S, Ben-Yehuda D, Schiller G, Landolfi R, Mizoguchi H, Koeffler HP. 1998. Chromosome band 1p36 contains a putative tumor suppressor gene important in the evolution of chronic myelocytic leukemia. Blood 92:3405-3409.
29. Muraosa Y, Takahashi K, Yoshizawa M, Shibahara S. 1996. cDNA cloning of a novel protein containing two zinc-finger domains that may function as a transcription factor for the human heme-oxygenase-1 gene. Eur J Biochem 235:471-479.
30. Nagai H, Negrini M, Carter SL, Gillum DR, Rosenberg AL, Schwartz GF, Croce CM. 1995. Detection and cloning of a common region of loss of heterozygosity at chromosome 1p in breast cancer. Cancer Res 55:1752-1757.
31. Piao Z, Park C, Park JH, Kim H. 1998a. Allelotype analysis of hepatocellular carcinoma. Int J Cancer 75:29-33.
32. Piao Z, Park C, Park JH, Kim H. 1998b. Deletion mapping of chromosome 4q in hepatocellular carcinoma. Int J Cancer 79:356-360.
33. Shapiro VS, Lee P, Winoto A. 1995. Identification and cloning of the G3B cDNA encoding a 3′ segment of a protein binding to GATA-3. Gene 163:329-330.
34. Simon D, Knowles BB, Weith A. 1991. Abnormalities of chromosome 1 and loss of heterozygosity on 1p in primary hepatomas. Oncogene 6:765-770.
35. Tang B, Bottinger EP, Jakowlew SB, Bagnall KM, Mariano J, Anver MR, Letterio JJ, Wakefield LM. 1998. Transforming growth factor-beta1 is a new form of tumor suppressor with true haploid insufficiency. Nat Med 4:802-807.
36. Thompson FH, Taetle R, Trent JM, Liu Y, Massey-Brown K, Scott KM, Weinstein RS, Emerson JC, Alberts DS, Nelson MA. 1997. Band 1p36 abnormalities and t(1;17) in ovarian carcinoma. Cancer Genet Cytogenet 96:106-110.
37. Vargas MP, Zhuang Z, Wang C, Vortmeyer A, Linehan WM, Merino MJ. 1997. Loss of heterozygosity on the short arm of chromosomes 1 and 3 in sporadic pheochromocytoma and extra-adrenal paraganglioma. Hum Pathol 28:411-415.
38. Whang-Peng J, Knutsen T, Jaffe ES, Steinberg SM, Raffeld M, Zhao WP, Duffey P, Condron K, Yano T, Longo DL. 1995. Sequential analysis of 43 patients with non-Hodgkin's lymphoma: clinical correlations with cytogenetic, histologic, immunophenotyping, and molecular studies. Blood 85:203-216.
39. White PS, Maris JM, Beltinger C, Sulman E, Marshall HN, Fujimori M, Kaufman BA, Biegel JA, Allen C, Hilliard C. 1995. A region of consistent deletion in neuroblastoma maps within human chromosome 1p36.2-36.3. Proc Natl Acad Sci USA 92:5520-5524.
40. Williamson C, Pannett AA, Pang JT, Wooding C, McCarthy M, Sheppard MN, Monson J, Clayton RN, Thakker RV. 1997. Localization of a gene causing endocrine neoplasia to a 4 cM region on chromosome 1p35-p36. J Med Genet 34:617-619.