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Volumn 143, Issue 1, 2012, Pages

MiR-375 inhibits autophagy and reduces viability of hepatocellular carcinoma cells under hypoxic conditions

Author keywords

Cell Death; Gene Expression; Liver Cancer; mRNA Processing

Indexed keywords

ANTINEOPLASTIC AGENT; BAFILOMYCIN A1; MICRORNA 375; PHOSPHOINOSITIDE DEPENDENT PROTEIN KINASE 1; PROTEIN KINASE B;

EID: 84862750365     PISSN: 00165085     EISSN: 15280012     Source Type: Journal    
DOI: 10.1053/j.gastro.2012.04.009     Document Type: Article
Times cited : (270)

References (64)
  • 2
    • 57349090407 scopus 로고    scopus 로고
    • Gene expression in fixed tissues and outcome in hepatocellular carcinoma
    • Y. Hoshida, A. Villanueva, M. Kobayashi Gene expression in fixed tissues and outcome in hepatocellular carcinoma N Engl J Med 359 2008 1995 2004
    • (2008) N Engl J Med , vol.359 , pp. 1995-2004
    • Hoshida, Y.1    Villanueva, A.2    Kobayashi, M.3
  • 3
    • 69949112039 scopus 로고    scopus 로고
    • Autophagy is required during cycling hypoxia to lower production of reactive oxygen species
    • K.M. Rouschop, C.H. Ramaekers, M.B. Schaaf Autophagy is required during cycling hypoxia to lower production of reactive oxygen species Radiother Oncol 92 2009 411 416
    • (2009) Radiother Oncol , vol.92 , pp. 411-416
    • Rouschop, K.M.1    Ramaekers, C.H.2    Schaaf, M.B.3
  • 4
    • 77951228508 scopus 로고    scopus 로고
    • Hypoxia-induced autophagy: Cell death or cell survival?
    • N.M. Mazure, J. Pouyssegur Hypoxia-induced autophagy: cell death or cell survival? Curr Opin Cell Biol 22 2010 177 180
    • (2010) Curr Opin Cell Biol , vol.22 , pp. 177-180
    • Mazure, N.M.1    Pouyssegur, J.2
  • 5
    • 33745713171 scopus 로고    scopus 로고
    • Autophagy promotes tumor cell survival and restricts necrosis, inflammation, and tumorigenesis
    • K. Degenhardt, R. Mathew, B. Beaudoin Autophagy promotes tumor cell survival and restricts necrosis, inflammation, and tumorigenesis Cancer Cell 10 2006 51 64
    • (2006) Cancer Cell , vol.10 , pp. 51-64
    • Degenhardt, K.1    Mathew, R.2    Beaudoin, B.3
  • 7
    • 78649464206 scopus 로고    scopus 로고
    • Autophagy is a therapeutic target in anticancer drug resistance
    • S. Chen, S.K. Rehman, W. Zhang Autophagy is a therapeutic target in anticancer drug resistance Biochim Biophys Acta 1806 2010 220 229
    • (2010) Biochim Biophys Acta , vol.1806 , pp. 220-229
    • Chen, S.1    Rehman, S.K.2    Zhang, W.3
  • 8
    • 70349320158 scopus 로고    scopus 로고
    • Causes and consequences of microRNA dysregulation in cancer
    • C.M. Croce Causes and consequences of microRNA dysregulation in cancer Nat Rev Genet 10 2009 704 714
    • (2009) Nat Rev Genet , vol.10 , pp. 704-714
    • Croce, C.M.1
  • 9
    • 69449097865 scopus 로고    scopus 로고
    • Regulation of autophagy by a beclin 1-targeted microRNA, miR-30a, in cancer cells
    • H. Zhu, H. Wu, X. Liu Regulation of autophagy by a beclin 1-targeted microRNA, miR-30a, in cancer cells Autophagy 5 2009 816 823
    • (2009) Autophagy , vol.5 , pp. 816-823
    • Zhu, H.1    Wu, H.2    Liu, X.3
  • 10
    • 81255143302 scopus 로고    scopus 로고
    • MicroRNA-101 is a potent inhibitor of autophagy
    • L.B. Frankel, J. Wen, M. Lees microRNA-101 is a potent inhibitor of autophagy Embo J 30 2011 4628 4641
    • (2011) Embo J , vol.30 , pp. 4628-4641
    • Frankel, L.B.1    Wen, J.2    Lees, M.3
  • 11
    • 81855227722 scopus 로고    scopus 로고
    • Phospho-DeltaNp63alpha/miR-885-3p axis in tumor cell life and cell death upon cisplatin exposure
    • Y. Huang, A.Y. Chuang, E.A. Ratovitski Phospho-DeltaNp63alpha/miR-885-3p axis in tumor cell life and cell death upon cisplatin exposure Cell Cycle 10 2011 3938 3947
    • (2011) Cell Cycle , vol.10 , pp. 3938-3947
    • Huang, Y.1    Chuang, A.Y.2    Ratovitski, E.A.3
  • 12
    • 84863809403 scopus 로고    scopus 로고
    • MicroRNA-375 targets AEG-1 in hepatocellular carcinoma and suppresses liver cancer cell growth in vitro and in vivo
    • [Epub ahead of print]
    • X.X. He, Y. Chang, F.Y. Meng MicroRNA-375 targets AEG-1 in hepatocellular carcinoma and suppresses liver cancer cell growth in vitro and in vivo Oncogene 2011 Nov 7 [Epub ahead of print]
    • (2011) Oncogene
    • He, X.X.1    Chang, Y.2    Meng, F.Y.3
  • 13
    • 33746864818 scopus 로고    scopus 로고
    • Regulation of human nitric oxide synthase 2 expression by Wnt beta-catenin signaling
    • Q. Du, K.S. Park, Z. Guo Regulation of human nitric oxide synthase 2 expression by Wnt beta-catenin signaling Cancer Res 66 2006 7024 7031
    • (2006) Cancer Res , vol.66 , pp. 7024-7031
    • Du, Q.1    Park, K.S.2    Guo, Z.3
  • 14
    • 80053420059 scopus 로고    scopus 로고
    • Targeting autophagy enhances sorafenib lethality for hepatocellular carcinoma via ER stress-related apoptosis
    • Y.H. Shi, Z.B. Ding, J. Zhou Targeting autophagy enhances sorafenib lethality for hepatocellular carcinoma via ER stress-related apoptosis Autophagy 7 2011 1159 1172
    • (2011) Autophagy , vol.7 , pp. 1159-1172
    • Shi, Y.H.1    Ding, Z.B.2    Zhou, J.3
  • 15
    • 0034244658 scopus 로고    scopus 로고
    • A stable system for the high-titer production of multiply attenuated lentiviral vectors
    • N. Klages, R. Zufferey, D. Trono A stable system for the high-titer production of multiply attenuated lentiviral vectors Mol Ther 2 2000 170 176
    • (2000) Mol Ther , vol.2 , pp. 170-176
    • Klages, N.1    Zufferey, R.2    Trono, D.3
  • 16
    • 66449083078 scopus 로고    scopus 로고
    • ULK1.ATG13.FIP200 complex mediates mTOR signaling and is essential for autophagy
    • I.G. Ganley, H. Lam du, J. Wang ULK1.ATG13.FIP200 complex mediates mTOR signaling and is essential for autophagy J Biol Chem 284 2009 12297 12305
    • (2009) J Biol Chem , vol.284 , pp. 12297-12305
    • Ganley, I.G.1    Lam Du, H.2    Wang, J.3
  • 17
    • 0032563798 scopus 로고    scopus 로고
    • A protein conjugation system essential for autophagy
    • N. Mizushima, T. Noda, T. Yoshimori A protein conjugation system essential for autophagy Nature 395 1998 395 398
    • (1998) Nature , vol.395 , pp. 395-398
    • Mizushima, N.1    Noda, T.2    Yoshimori, T.3
  • 18
    • 77952766891 scopus 로고    scopus 로고
    • Autophagy: Assays and artifacts
    • S. Barth, D. Glick, K.F. Macleod Autophagy: assays and artifacts J Pathol 221 2010 117 124
    • (2010) J Pathol , vol.221 , pp. 117-124
    • Barth, S.1    Glick, D.2    MacLeod, K.F.3
  • 19
    • 38949108670 scopus 로고    scopus 로고
    • Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes
    • D.J. Klionsky, H. Abeliovich, P. Agostinis Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes Autophagy 4 2008 151 175
    • (2008) Autophagy , vol.4 , pp. 151-175
    • Klionsky, D.J.1    Abeliovich, H.2    Agostinis, P.3
  • 20
    • 9144270691 scopus 로고    scopus 로고
    • A pancreatic islet-specific microRNA regulates insulin secretion
    • M.N. Poy, L. Eliasson, J. Krutzfeldt A pancreatic islet-specific microRNA regulates insulin secretion Nature 432 2004 226 230
    • (2004) Nature , vol.432 , pp. 226-230
    • Poy, M.N.1    Eliasson, L.2    Krutzfeldt, J.3
  • 21
    • 0034329418 scopus 로고    scopus 로고
    • LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing
    • Y. Kabeya, N. Mizushima, T. Ueno LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing Embo J 19 2000 5720 5728
    • (2000) Embo J , vol.19 , pp. 5720-5728
    • Kabeya, Y.1    Mizushima, N.2    Ueno, T.3
  • 22
    • 77950250954 scopus 로고    scopus 로고
    • MicroRNA-375 is downregulated in gastric carcinomas and regulates cell survival by targeting PDK1 and 14-3-3zeta
    • Y. Tsukamoto, C. Nakada, T. Noguchi MicroRNA-375 is downregulated in gastric carcinomas and regulates cell survival by targeting PDK1 and 14-3-3zeta Cancer Res 70 2010 2339 2349
    • (2010) Cancer Res , vol.70 , pp. 2339-2349
    • Tsukamoto, Y.1    Nakada, C.2    Noguchi, T.3
  • 23
    • 58149350343 scopus 로고    scopus 로고
    • MiR-375 targets 3′-phosphoinositide-dependent protein kinase-1 and regulates glucose-induced biological responses in pancreatic beta-cells
    • A. El Ouaamari, N. Baroukh, G.A. Martens miR-375 targets 3′-phosphoinositide-dependent protein kinase-1 and regulates glucose-induced biological responses in pancreatic beta-cells Diabetes 57 2008 2708 2717
    • (2008) Diabetes , vol.57 , pp. 2708-2717
    • El Ouaamari, A.1    Baroukh, N.2    Martens, G.A.3
  • 24
    • 53749104349 scopus 로고    scopus 로고
    • Akt inhibition promotes autophagy and sensitizes PTEN-null tumors to lysosomotropic agents
    • M. Degtyarev, A. De Maziere, C. Orr Akt inhibition promotes autophagy and sensitizes PTEN-null tumors to lysosomotropic agents J Cell Biol 183 2008 101 116
    • (2008) J Cell Biol , vol.183 , pp. 101-116
    • Degtyarev, M.1    De Maziere, A.2    Orr, C.3
  • 25
    • 78649300971 scopus 로고    scopus 로고
    • P62/SQSTM1 is required for Parkin-induced mitochondrial clustering but not mitophagy; VDAC1 is dispensable for both
    • D. Narendra, L.A. Kane, D.N. Hauser p62/SQSTM1 is required for Parkin-induced mitochondrial clustering but not mitophagy; VDAC1 is dispensable for both Autophagy 6 2010 1090 1106
    • (2010) Autophagy , vol.6 , pp. 1090-1106
    • Narendra, D.1    Kane, L.A.2    Hauser, D.N.3
  • 26
    • 77954695260 scopus 로고    scopus 로고
    • P62/SQSTM1 cooperates with Parkin for perinuclear clustering of depolarized mitochondria
    • K. Okatsu, K. Saisho, M. Shimanuki p62/SQSTM1 cooperates with Parkin for perinuclear clustering of depolarized mitochondria Genes Cells 15 2010 887 900
    • (2010) Genes Cells , vol.15 , pp. 887-900
    • Okatsu, K.1    Saisho, K.2    Shimanuki, M.3
  • 27
    • 28544443984 scopus 로고    scopus 로고
    • Promoting apoptosis as a strategy for cancer drug discovery
    • S.W. Fesik Promoting apoptosis as a strategy for cancer drug discovery Nat Rev Cancer 5 2005 876 885
    • (2005) Nat Rev Cancer , vol.5 , pp. 876-885
    • Fesik, S.W.1
  • 28
    • 77950626836 scopus 로고    scopus 로고
    • MicroRNA-375 targets Hippo-signaling effector YAP in liver cancer and inhibits tumor properties
    • Liu AM, Poon RT, Luk JM. MicroRNA-375 targets Hippo-signaling effector YAP in liver cancer and inhibits tumor properties. Biochem Biophys Res Commun; 394:623-627.
    • Biochem Biophys Res Commun , vol.394 , pp. 623-627
    • Liu, A.M.1    Poon, R.T.2    Luk, J.M.3
  • 29
    • 77955708471 scopus 로고    scopus 로고
    • MiR-375 frequently downregulated in gastric cancer inhibits cell proliferation by targeting JAK2
    • L. Ding, Y. Xu, W. Zhang MiR-375 frequently downregulated in gastric cancer inhibits cell proliferation by targeting JAK2 Cell Res 20 2010 784 793
    • (2010) Cell Res , vol.20 , pp. 784-793
    • Ding, L.1    Xu, Y.2    Zhang, W.3
  • 30
    • 79953856887 scopus 로고    scopus 로고
    • Involvement of autophagy in oncogenic K-Ras-induced malignant cell transformation
    • M.J. Kim, S.J. Woo, C.H. Yoon Involvement of autophagy in oncogenic K-Ras-induced malignant cell transformation J Biol Chem 286 2011 12924 12932
    • (2011) J Biol Chem , vol.286 , pp. 12924-12932
    • Kim, M.J.1    Woo, S.J.2    Yoon, C.H.3
  • 31
    • 79955676537 scopus 로고    scopus 로고
    • Induction of autophagy by drug-resistant esophageal cancer cells promotes their survival and recovery following treatment with chemotherapeutics
    • T.R. O'Donovan, G.C. O'Sullivan, S.L. McKenna Induction of autophagy by drug-resistant esophageal cancer cells promotes their survival and recovery following treatment with chemotherapeutics Autophagy 7 2011 509 524
    • (2011) Autophagy , vol.7 , pp. 509-524
    • O'Donovan, T.R.1    O'Sullivan, G.C.2    McKenna, S.L.3
  • 32
    • 80053420059 scopus 로고    scopus 로고
    • Targeting autophagy enhances sorafenib lethality for hepatocellular carcinoma via ER stress-related apoptosis
    • Y.H. Shi, Z.B. Ding, J. Zhou Targeting autophagy enhances sorafenib lethality for hepatocellular carcinoma via ER stress-related apoptosis Autophagy 7 2011 1159 1172
    • (2011) Autophagy , vol.7 , pp. 1159-1172
    • Shi, Y.H.1    Ding, Z.B.2    Zhou, J.3
  • 33
    • 72049108924 scopus 로고    scopus 로고
    • Meta-regulation: MicroRNA regulation of glucose and lipid metabolism
    • F.C. Lynn Meta-regulation: microRNA regulation of glucose and lipid metabolism Trends Endocrinol Metab 20 2009 452 459
    • (2009) Trends Endocrinol Metab , vol.20 , pp. 452-459
    • Lynn, F.C.1
  • 34
    • 77950626836 scopus 로고    scopus 로고
    • MicroRNA-375 targets Hippo-signaling effector YAP in liver cancer and inhibits tumor properties
    • A.M. Liu, R.T. Poon, J.M. Luk MicroRNA-375 targets Hippo-signaling effector YAP in liver cancer and inhibits tumor properties Biochem Biophys Res Commun 394 2010 623 627
    • (2010) Biochem Biophys Res Commun , vol.394 , pp. 623-627
    • Liu, A.M.1    Poon, R.T.2    Luk, J.M.3
  • 35
    • 15544382574 scopus 로고    scopus 로고
    • Diabetes increases the risk of hepatocellular carcinoma in the United States: A population based case control study
    • J.A. Davila, R.O. Morgan, Y. Shaib Diabetes increases the risk of hepatocellular carcinoma in the United States: a population based case control study Gut 54 2005 533 539
    • (2005) Gut , vol.54 , pp. 533-539
    • Davila, J.A.1    Morgan, R.O.2    Shaib, Y.3
  • 36
    • 0036547417 scopus 로고    scopus 로고
    • Death and anti-death: Tumour resistance to apoptosis
    • F.H. Igney, P.H. Krammer Death and anti-death: tumour resistance to apoptosis Nat Rev Cancer 2 2002 277 288
    • (2002) Nat Rev Cancer , vol.2 , pp. 277-288
    • Igney, F.H.1    Krammer, P.H.2
  • 37
    • 71549124671 scopus 로고    scopus 로고
    • Autophagy is activated by TGF-beta and potentiates TGF-beta-mediated growth inhibition in human hepatocellular carcinoma cells
    • K. Kiyono, H.I. Suzuki, H. Matsuyama Autophagy is activated by TGF-beta and potentiates TGF-beta-mediated growth inhibition in human hepatocellular carcinoma cells Cancer Res 69 2009 8844 8852
    • (2009) Cancer Res , vol.69 , pp. 8844-8852
    • Kiyono, K.1    Suzuki, H.I.2    Matsuyama, H.3
  • 38
    • 77951214016 scopus 로고    scopus 로고
    • Mammalian autophagy: Core molecular machinery and signaling regulation
    • Z. Yang, D.J. Klionsky Mammalian autophagy: core molecular machinery and signaling regulation Curr Opin Cell Biol 22 2010 124 131
    • (2010) Curr Opin Cell Biol , vol.22 , pp. 124-131
    • Yang, Z.1    Klionsky, D.J.2
  • 39
    • 84856039513 scopus 로고    scopus 로고
    • CERT depletion predicts chemotherapy benefit and mediates cytotoxic and polyploid-specific cancer cell death through autophagy induction
    • A.J. Lee, R. Roylance, J. Sander CERT depletion predicts chemotherapy benefit and mediates cytotoxic and polyploid-specific cancer cell death through autophagy induction J Pathol 226 2012 482 494
    • (2012) J Pathol , vol.226 , pp. 482-494
    • Lee, A.J.1    Roylance, R.2    Sander, J.3
  • 40
    • 80054991467 scopus 로고    scopus 로고
    • MiR-375 is down-regulated in squamous cervical cancer and inhibits cell migration and invasion via targeting transcription factor SP1
    • F. Wang, Y. Li, J. Zhou miR-375 is down-regulated in squamous cervical cancer and inhibits cell migration and invasion via targeting transcription factor SP1 Am J Pathol 179 2011 2580 2588
    • (2011) Am J Pathol , vol.179 , pp. 2580-2588
    • Wang, F.1    Li, Y.2    Zhou, J.3
  • 41
    • 78649300971 scopus 로고    scopus 로고
    • P62/SQSTM1 is required for Parkin-induced mitochondrial clustering but not mitophagy; VDAC1 is dispensable for both
    • D. Narendra, L.A. Kane, D.N. Hauser p62/SQSTM1 is required for Parkin-induced mitochondrial clustering but not mitophagy; VDAC1 is dispensable for both Autophagy 6 2010 1090 1106
    • (2010) Autophagy , vol.6 , pp. 1090-1106
    • Narendra, D.1    Kane, L.A.2    Hauser, D.N.3
  • 42
    • 75949130828 scopus 로고    scopus 로고
    • PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1
    • S. Geisler, K.M. Holmstrom, D. Skujat PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1 Nat Cell Biol 12 2010 119 131
    • (2010) Nat Cell Biol , vol.12 , pp. 119-131
    • Geisler, S.1    Holmstrom, K.M.2    Skujat, D.3
  • 43
    • 77956252454 scopus 로고    scopus 로고
    • Nix is critical to two distinct phases of mitophagy, reactive oxygen species-mediated autophagy induction and Parkin-ubiquitin-p62-mediated mitochondrial priming
    • W.X. Ding, H.M. Ni, M. Li Nix is critical to two distinct phases of mitophagy, reactive oxygen species-mediated autophagy induction and Parkin-ubiquitin-p62-mediated mitochondrial priming J Biol Chem 285 2010 27879 27890
    • (2010) J Biol Chem , vol.285 , pp. 27879-27890
    • Ding, W.X.1    Ni, H.M.2    Li, M.3
  • 44
    • 34548259958 scopus 로고    scopus 로고
    • P62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy
    • S. Pankiv, T.H. Clausen, T. Lamark p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy J Biol Chem 282 2007 24131 24145
    • (2007) J Biol Chem , vol.282 , pp. 24131-24145
    • Pankiv, S.1    Clausen, T.H.2    Lamark, T.3
  • 46
    • 77954695260 scopus 로고    scopus 로고
    • P62/SQSTM1 cooperates with Parkin for perinuclear clustering of depolarized mitochondria
    • K. Okatsu, K. Saisho, M. Shimanuki p62/SQSTM1 cooperates with Parkin for perinuclear clustering of depolarized mitochondria Genes Cells 15 2010 887 900
    • (2010) Genes Cells , vol.15 , pp. 887-900
    • Okatsu, K.1    Saisho, K.2    Shimanuki, M.3
  • 47
    • 74049126112 scopus 로고    scopus 로고
    • The adaptor protein p62/SQSTM1 targets invading bacteria to the autophagy pathway
    • Y.T. Zheng, S. Shahnazari, A. Brech The adaptor protein p62/SQSTM1 targets invading bacteria to the autophagy pathway J Immunol 183 2009 5909 5916
    • (2009) J Immunol , vol.183 , pp. 5909-5916
    • Zheng, Y.T.1    Shahnazari, S.2    Brech, A.3
  • 48
    • 77955354069 scopus 로고    scopus 로고
    • AMPK- and p62/SQSTM1-dependent autophagy mediate resveratrol-induced cell death in chronic myelogenous leukemia
    • [Epub ahead of print]
    • A. Puissant, P. Auberger AMPK- and p62/SQSTM1-dependent autophagy mediate resveratrol-induced cell death in chronic myelogenous leukemia Autophagy 6 2010 [Epub ahead of print]
    • (2010) Autophagy , vol.6
    • Puissant, A.1    Auberger, P.2
  • 49
    • 78651282673 scopus 로고    scopus 로고
    • P62 Targeting to the autophagosome formation site requires self-oligomerization but not LC3 binding
    • E. Itakura, N. Mizushima p62 Targeting to the autophagosome formation site requires self-oligomerization but not LC3 binding J Cell Biol 192 2011 17 27
    • (2011) J Cell Biol , vol.192 , pp. 17-27
    • Itakura, E.1    Mizushima, N.2
  • 50
    • 79952348751 scopus 로고    scopus 로고
    • The ubiquitin-binding adaptor proteins p62/SQSTM1 and NDP52 are recruited independently to bacteria-associated microdomains to target Salmonella to the autophagy pathway
    • M. Cemma, P.K. Kim, J.H. Brumell The ubiquitin-binding adaptor proteins p62/SQSTM1 and NDP52 are recruited independently to bacteria-associated microdomains to target Salmonella to the autophagy pathway Autophagy 7 2010 22 26
    • (2010) Autophagy , vol.7 , pp. 22-26
    • Cemma, M.1    Kim, P.K.2    Brumell, J.H.3
  • 51
    • 66449114033 scopus 로고    scopus 로고
    • P62 at the crossroads of autophagy, apoptosis, and cancer
    • J. Moscat, M.T. Diaz-Meco p62 at the crossroads of autophagy, apoptosis, and cancer Cell 137 2009 1001 1004
    • (2009) Cell , vol.137 , pp. 1001-1004
    • Moscat, J.1    Diaz-Meco, M.T.2
  • 52
    • 41249084239 scopus 로고    scopus 로고
    • The signaling adaptor p62 is an important NF-kappaB mediator in tumorigenesis
    • A. Duran, J.F. Linares, A.S. Galvez The signaling adaptor p62 is an important NF-kappaB mediator in tumorigenesis Cancer Cell 13 2008 343 354
    • (2008) Cancer Cell , vol.13 , pp. 343-354
    • Duran, A.1    Linares, J.F.2    Galvez, A.S.3
  • 53
    • 84863809403 scopus 로고    scopus 로고
    • MicroRNA-375 targets AEG-1 in hepatocellular carcinoma and suppresses liver cancer cell growth in vitro and in vivo
    • [Epub ahead of print]
    • X.X. He, Y. Chang, F.Y. Meng MicroRNA-375 targets AEG-1 in hepatocellular carcinoma and suppresses liver cancer cell growth in vitro and in vivo Oncogene 2011 Nov 7 [Epub ahead of print]
    • (2011) Oncogene
    • He, X.X.1    Chang, Y.2    Meng, F.Y.3
  • 54
    • 68349160639 scopus 로고    scopus 로고
    • Bead-based microarray analysis of microRNA expression in hepatocellular carcinoma: MiR-338 is downregulated
    • X.H. Huang, Q. Wang, J.S. Chen Bead-based microarray analysis of microRNA expression in hepatocellular carcinoma: miR-338 is downregulated Hepatol Res 39 2009 786 794
    • (2009) Hepatol Res , vol.39 , pp. 786-794
    • Huang, X.H.1    Wang, Q.2    Chen, J.S.3
  • 55
    • 46249083024 scopus 로고    scopus 로고
    • MicroRNA profiling in hepatocellular tumors is associated with clinical features and oncogene/tumor suppressor gene mutations
    • Y. Ladeiro, G. Couchy, C. Balabaud MicroRNA profiling in hepatocellular tumors is associated with clinical features and oncogene/tumor suppressor gene mutations Hepatology 47 2008 1955 1963
    • (2008) Hepatology , vol.47 , pp. 1955-1963
    • Ladeiro, Y.1    Couchy, G.2    Balabaud, C.3
  • 56
    • 37249006781 scopus 로고    scopus 로고
    • Microarray analysis of microRNA expression in hepatocellular carcinoma and non-tumorous tissues without viral hepatitis
    • Y.S. Huang, Y. Dai, X.F. Yu Microarray analysis of microRNA expression in hepatocellular carcinoma and non-tumorous tissues without viral hepatitis J Gastroenterol Hepatol 23 2008 87 94
    • (2008) J Gastroenterol Hepatol , vol.23 , pp. 87-94
    • Huang, Y.S.1    Dai, Y.2    Yu, X.F.3
  • 57
    • 78649258023 scopus 로고    scopus 로고
    • MiR-146b-5p suppresses EGFR expression and reduces in vitro migration and invasion of glioma
    • M. Katakowski, X. Zheng, F. Jiang MiR-146b-5p suppresses EGFR expression and reduces in vitro migration and invasion of glioma Cancer Invest 28 2010 1024 1030
    • (2010) Cancer Invest , vol.28 , pp. 1024-1030
    • Katakowski, M.1    Zheng, X.2    Jiang, F.3
  • 58
    • 79955836048 scopus 로고    scopus 로고
    • MicroRNA miR-885-5p targets CDK2 and MCM5, activates p53 and inhibits proliferation and survival
    • E.A. Afanasyeva, P. Mestdagh, C. Kumps MicroRNA miR-885-5p targets CDK2 and MCM5, activates p53 and inhibits proliferation and survival Cell Death Differ 18 2011 974 984
    • (2011) Cell Death Differ , vol.18 , pp. 974-984
    • Afanasyeva, E.A.1    Mestdagh, P.2    Kumps, C.3
  • 59
    • 34447117003 scopus 로고    scopus 로고
    • Cyclin G1 is a target of miR-122a, a microRNA frequently down-regulated in human hepatocellular carcinoma
    • L. Gramantieri, M. Ferracin, F. Fornari Cyclin G1 is a target of miR-122a, a microRNA frequently down-regulated in human hepatocellular carcinoma Cancer Res 67 2007 6092 6099
    • (2007) Cancer Res , vol.67 , pp. 6092-6099
    • Gramantieri, L.1    Ferracin, M.2    Fornari, F.3
  • 60
    • 42249089850 scopus 로고    scopus 로고
    • MicroRNA gene expression profile of hepatitis C virus-associated hepatocellular carcinoma
    • H. Varnholt, U. Drebber, F. Schulze MicroRNA gene expression profile of hepatitis C virus-associated hepatocellular carcinoma Hepatology 47 2008 1223 1232
    • (2008) Hepatology , vol.47 , pp. 1223-1232
    • Varnholt, H.1    Drebber, U.2    Schulze, F.3
  • 61
    • 33646157967 scopus 로고    scopus 로고
    • Comprehensive analysis of microRNA expression patterns in hepatocellular carcinoma and non-tumorous tissues
    • Y. Murakami, T. Yasuda, K. Saigo Comprehensive analysis of microRNA expression patterns in hepatocellular carcinoma and non-tumorous tissues Oncogene 25 2006 2537 2545
    • (2006) Oncogene , vol.25 , pp. 2537-2545
    • Murakami, Y.1    Yasuda, T.2    Saigo, K.3
  • 62
    • 34547524771 scopus 로고    scopus 로고
    • MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer
    • F. Meng, R. Henson, H. Wehbe-Janek MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer Gastroenterology 133 2007 647 658
    • (2007) Gastroenterology , vol.133 , pp. 647-658
    • Meng, F.1    Henson, R.2    Wehbe-Janek, H.3
  • 63
    • 38949184246 scopus 로고    scopus 로고
    • Association of microRNA expression in hepatocellular carcinomas with hepatitis infection, cirrhosis, and patient survival
    • J. Jiang, Y. Gusev, I. Aderca Association of microRNA expression in hepatocellular carcinomas with hepatitis infection, cirrhosis, and patient survival Clin Cancer Res 14 2008 419 427
    • (2008) Clin Cancer Res , vol.14 , pp. 419-427
    • Jiang, J.1    Gusev, Y.2    Aderca, I.3
  • 64
    • 57149138434 scopus 로고    scopus 로고
    • MicroRNA involvement in hepatocellular carcinoma
    • L. Gramantieri, F. Fornari, E. Callegari MicroRNA involvement in hepatocellular carcinoma J Cell Mol Med 12 2008 2189 2204
    • (2008) J Cell Mol Med , vol.12 , pp. 2189-2204
    • Gramantieri, L.1    Fornari, F.2    Callegari, E.3


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