MicroRNA-18a Prevents Estrogen Receptor-α Expression, Promoting Proliferation of Hepatocellular Carcinoma Cells

Gastroenterology

Volumn 136, Issue 2, 2009, Pages 683-693

  Liu, Wan Hsin ^a   Yeh, Shiou Hwei ^a   Lu, Cho Chun ^a   Yu, Sung Liang ^a   Chen, Hsuan Yu ^b   Lin, Chien Yu ^b   Chen, Ding Shinn ^a,c   Chen, Pei Jer ^a,c  

^a NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^b INSTITUTE OF STATISTICAL SCIENCE   (Taiwan)

^c NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

ESTROGEN RECEPTOR ALPHA; LUCIFERASE; MICRORNA; MICRORNA 18A; UNCLASSIFIED DRUG;

3' UNTRANSLATED REGION; ARTICLE; BIOGENESIS; CARCINOMA CELL; CELL PROLIFERATION; FEMALE; GENE OVEREXPRESSION; HORMONE METABOLISM; HUMAN; HUMAN CELL; HUMAN TISSUE; LIVER CELL CARCINOMA; MALE; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEX DIFFERENCE;

EID: 84984539125     PISSN: 00165085     EISSN: None     Source Type: Journal    
DOI: 10.1053/j.gastro.2008.10.029     Document Type: Article

References (34)

1. Cancer incidence in five continents. IARC Sci Publ Volume VIII (2002) 1-781
2. Yu M.W., Cheng S.W., Lin M.W., et al. Androgen-receptor gene CAG repeats, plasma testosterone levels, and risk of hepatitis B-related hepatocellular carcinoma. J Natl Cancer Inst 92 (2000) 2023-2028
3. Yu M.W., Yang Y.C., Yang S.Y., et al. Hormonal markers and hepatitis B virus-related hepatocellular carcinoma risk: a nested case-control study among men. J Natl Cancer Inst 93 (2001) 1644-1651
4. Toh Y.C. Effect of neonatal castration on liver tumor induction by N-2-fluorenylacetamide in suckling BALB/c mice. Carcinogenesis 2 (1981) 1219-1221
5. Yu M.W., Chang H.C., Chang S.C., et al. Role of reproductive factors in hepatocellular carcinoma: impact on hepatitis B- and C-related risk. Hepatology 38 (2003) 1393-1400
6. Vesselinovitch S.D., Itze L., Mihailovich N., et al. Modifying role of partial hepatectomy and gonadectomy in ethylnitrosourea-induced hepatocarcinogenesis. Cancer Res 40 (1980) 1538-1542
7. Nakatani T., Roy G., Fujimoto N., et al. Sex hormone dependency of diethylnitrosamine-induced liver tumors in mice and chemoprevention by leuprorelin. Jpn J Cancer Res 92 (2001) 249-256
8. Naugler W.E., Sakurai T., Kim S., et al. Gender disparity in liver cancer due to sex differences in MyD88-dependent IL-6 production. Science 317 (2007) 121-124
9. Chiu C.M., Yeh S.H., Chen P.J., et al. Hepatitis B virus X protein enhances androgen receptor-responsive gene expression depending on androgen level. Proc Natl Acad Sci U S A 104 (2007) 2571-2578
10. Zamore P.D., and Haley B. Ribo-gnome: the big world of small RNAs. Science 309 (2005) 1519-1524
11. Blenkiron C., and Miska E.A. miRNAs in cancer: approaches, aetiology, diagnostics and therapy. Hum Mol Genet 16 Spec No 1 (2007) R106-R113
12. Jiang J., Gusev Y., Aderca I., et al. Association of MicroRNA expression in hepatocellular carcinomas with hepatitis infection, cirrhosis, and patient survival. Clin Cancer Res 14 (2008) 419-427
13. Gramantieri L., Ferracin M., Fornari F., et al. Cyclin G1 is a target of miR-122a, a microRNA frequently down-regulated in human hepatocellular carcinoma. Cancer Res 67 (2007) 6092-6099
14. Ladeiro Y., Couchy G., Balabaud C., et al. MicroRNA profiling in hepatocellular tumors is associated with clinical features and oncogene/tumor suppressor gene mutations. Hepatology 47 (2008) 1955-1963
15. Murakami Y., Yasuda T., Saigo K., et al. Comprehensive analysis of microRNA expression patterns in hepatocellular carcinoma and non-tumorous tissues. Oncogene 25 (2006) 2537-2545
16. Wang Y., Lee A.T., Ma J.Z., et al. Profiling microRNA expression in hepatocellular carcinoma reveals microRNA-224 up-regulation and apoptosis inhibitor-5 as a microRNA-224-specific target. J Biol Chem 283 (2008) 13205-13215
17. Wong Q.W., Lung R.W., Law P.T., et al. MicroRNA-223 is commonly repressed in hepatocellular carcinoma and potentiates expression of Stathmin1. Gastroenterology 135 (2008) 257-269
18. Livak K.J., and Schmittgen T.D. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-ΔΔC(T)) Method. Methods 25 (2001) 402-408
19. Benjamini Y., and Hochberg Y. Controlling the false discovery rate: a practical and powerful approach to multiple testing. J R Stat Soc 57 (1995) 289-300
20. Krek A., Grun D., Poy M.N., et al. Combinatorial microRNA target predictions. Nat Genet 37 (2005) 495-500
21. Lewis B.P., Burge C.B., and Bartel D.P. Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. Cell 120 (2005) 15-20
22. Vatolin S., Navaratne K., and Weil R.J. A novel method to detect functional microRNA targets. J Mol Biol 358 (2006) 983-996
23. Heldring N., Pike A., Andersson S., et al. Estrogen receptors: how do they signal and what are their targets. Physiol Rev 87 (2007) 905-931
24. Ng I.O., Ng M., and Fan S.T. Better survival in women with resected hepatocellular carcinoma is not related to tumor proliferation or expression of hormone receptors. Am J Gastroenterol 92 (1997) 1355-1358
25. Jonas S., Bechstein W.O., Heinze T., et al. Female sex hormone receptor status in advanced hepatocellular carcinoma and outcome after surgical resection. Surgery 121 (1997) 456-461
26. Nagasue N., Kohno H., Chang Y.C., et al. Clinicopathologic comparisons between estrogen receptor-positive and -negative hepatocellular carcinomas. Ann Surg 212 (1990) 150-154
27. Shen L., Ahuja N., Shen Y., et al. DNA methylation and environmental exposures in human hepatocellular carcinoma. J Natl Cancer Inst 94 (2002) 755-761
28. Kondo N., Toyama T., Sugiura H., et al. miR-206 Expression is down-regulated in estrogen receptor α-positive human breast cancer. Cancer Res 68 (2008) 5004-5008
29. Lizardi-Cervera J., Cuellar-Gamboa L., and Motola-Kuba D. Focal nodular hyperplasia and hepatic adenoma: a review. Ann Hepatol 5 (2006) 206-211
30. Pike M.C., and Spicer D.V. Hormonal contraception and chemoprevention of female cancers. Endocr Relat Cancer 7 (2000) 73-83
31. Dutertre M., and Smith C.L. Molecular mechanisms of selective estrogen receptor modulator (SERM) action. J Pharmacol Exp Ther 295 (2000) 431-437
32. He L., Thomson J.M., Hemann M.T., et al. A microRNA polycistron as a potential human oncogene. Nature 435 (2005) 828-833
33. Woods K., Thomson J.M., and Hammond S.M. Direct regulation of an oncogenic micro-RNA cluster by E2F transcription factors. J Biol Chem 282 (2007) 2130-2134
34. Guil S., and Caceres J.F. The multifunctional RNA-binding protein hnRNP A1 is required for processing of miR-18a. Nat Struct Mol Biol 14 (2007) 591-596