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Volumn 22, Issue 5, 2015, Pages 785-799

A novel literature-based approach to identify genetic and molecular predictors of survival in glioblastoma multiforme: Analysis of 14,678 patients using systematic review and meta-analytical tools

Author keywords

Adults; Glioblastoma; Meta analysis; Neurosurgery; Survival; Systematic review

Indexed keywords

BIOLOGICAL MARKER; CARBONATE DEHYDRATASE; CATHEPSIN; CYCLIN DEPENDENT KINASE INHIBITOR 2A; EPHRIN RECEPTOR A2; EPIDERMAL GROWTH FACTOR RECEPTOR; FAS ANTIGEN; FASCIN; HERMES ANTIGEN; HYPOXIA INDUCIBLE FACTOR 1; HYPOXIA INDUCIBLE FACTOR 1ALPHA; KI 67 ANTIGEN; METHYLATED DNA PROTEIN CYSTEINE METHYLTRANSFERASE; MITOGEN ACTIVATED PROTEIN KINASE; NESTIN; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN BAX; PROTEIN KINASE B; PROTEIN MDM2; PROTEIN P53; RAS PROTEIN; RETINOBLASTOMA PROTEIN; SURVIVIN; TELOMERASE REVERSE TRANSCRIPTASE; GENETIC MARKER;

EID: 84927178674     PISSN: 09675868     EISSN: 15322653     Source Type: Journal    
DOI: 10.1016/j.jocn.2014.10.029     Document Type: Review
Times cited : (32)

References (312)
  • 1
    • 20044366163 scopus 로고    scopus 로고
    • Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma
    • R. Stupp, W.P. Mason, and M.J. van den Bent Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma Engl J Med 352 2005 987 996
    • (2005) Engl J Med , vol.352 , pp. 987-996
    • Stupp, R.1    Mason, W.P.2    Van Den Bent, M.J.3
  • 2
    • 12144291692 scopus 로고    scopus 로고
    • Clinical trial substantiates the predictive value of O-6-methylguanine-DNA methyltransferase promoter methylation in glioblastoma patients treated with temozolomide
    • M.E. Hegi, A.C. Diserens, and S. Godard Clinical trial substantiates the predictive value of O-6-methylguanine-DNA methyltransferase promoter methylation in glioblastoma patients treated with temozolomide Clin Cancer Res 10 2004 1871 1874
    • (2004) Clin Cancer Res , vol.10 , pp. 1871-1874
    • Hegi, M.E.1    Diserens, A.C.2    Godard, S.3
  • 3
    • 67649873216 scopus 로고    scopus 로고
    • Extent of MGMT promoter methylation correlates with outcome in glioblastomas given temozolomide and radiotherapy
    • J. Dunn, A. Baborie, and F. Alam Extent of MGMT promoter methylation correlates with outcome in glioblastomas given temozolomide and radiotherapy Br J Cancer 101 2009 124 131
    • (2009) Br J Cancer , vol.101 , pp. 124-131
    • Dunn, J.1    Baborie, A.2    Alam, F.3
  • 4
    • 67651240322 scopus 로고    scopus 로고
    • Methylation status of the MGMT gene promoter fails to predict the clinical outcome of glioblastoma patients treated with ACNU plus cisplatin
    • C.K. Park, S.H. Park, and S.H. Lee Methylation status of the MGMT gene promoter fails to predict the clinical outcome of glioblastoma patients treated with ACNU plus cisplatin Neuropathology 29 2009 443 449
    • (2009) Neuropathology , vol.29 , pp. 443-449
    • Park, C.K.1    Park, S.H.2    Lee, S.H.3
  • 5
    • 51249098488 scopus 로고    scopus 로고
    • Anti-O6-methylguanine-methyltransferase (MGMT) immunohistochemistry in glioblastoma multiforme: Observer variability and lack of association with patient survival impede its use as clinical biomarker
    • M. Preusser, R. Charles Janzer, and J. Felsberg Anti-O6-methylguanine-methyltransferase (MGMT) immunohistochemistry in glioblastoma multiforme: observer variability and lack of association with patient survival impede its use as clinical biomarker Brain Pathol 18 2008 520 532
    • (2008) Brain Pathol , vol.18 , pp. 520-532
    • Preusser, M.1    Charles Janzer, R.2    Felsberg, J.3
  • 6
    • 44349136238 scopus 로고    scopus 로고
    • Prognostic molecular markers with no impact on decision-making: The paradox of gliomas based on a prospective study
    • M. Wager, P. Menei, and J. Guilhot Prognostic molecular markers with no impact on decision-making: the paradox of gliomas based on a prospective study Br J Cancer 98 2008 1830 1838
    • (2008) Br J Cancer , vol.98 , pp. 1830-1838
    • Wager, M.1    Menei, P.2    Guilhot, J.3
  • 7
    • 52949127312 scopus 로고    scopus 로고
    • An integrated genomic analysis of human glioblastoma multiforme
    • D.W. Parsons, S. Jones, and X. Zhang An integrated genomic analysis of human glioblastoma multiforme Science 321 2008 1807 1812
    • (2008) Science , vol.321 , pp. 1807-1812
    • Parsons, D.W.1    Jones, S.2    Zhang, X.3
  • 8
    • 70249097408 scopus 로고    scopus 로고
    • Isocitrate dehydrogenase 1 codon 132 mutation is an important prognostic biomarker in gliomas
    • M. Sanson, Y. Marie, and S. Paris Isocitrate dehydrogenase 1 codon 132 mutation is an important prognostic biomarker in gliomas J Clin Oncol 27 2009 4150 4154
    • (2009) J Clin Oncol , vol.27 , pp. 4150-4154
    • Sanson, M.1    Marie, Y.2    Paris, S.3
  • 9
    • 70349594347 scopus 로고    scopus 로고
    • Analysis of IDH1 and IDH2 mutations in Japanese glioma patients
    • Y. Sonoda, T. Kumabe, and T. Nakamura Analysis of IDH1 and IDH2 mutations in Japanese glioma patients Cancer Sci 100 2009 1996 1998
    • (2009) Cancer Sci , vol.100 , pp. 1996-1998
    • Sonoda, Y.1    Kumabe, T.2    Nakamura, T.3
  • 10
    • 73349103157 scopus 로고    scopus 로고
    • Molecular predictors of progression-free and overall survival in patients with newly diagnosed glioblastoma: A prospective translational study of the German glioma network
    • M. Weller, J. Felsberg, and C. Hartmann Molecular predictors of progression-free and overall survival in patients with newly diagnosed glioblastoma: a prospective translational study of the German glioma network J Clin Oncol 27 2009 5743 5750
    • (2009) J Clin Oncol , vol.27 , pp. 5743-5750
    • Weller, M.1    Felsberg, J.2    Hartmann, C.3
  • 11
    • 60849115270 scopus 로고    scopus 로고
    • IDH1 and IDH2 mutations in gliomas
    • H. Yan, D.W. Parsons, and G. Jin IDH1 and IDH2 mutations in gliomas N Engl J Med 360 2009 765 773
    • (2009) N Engl J Med , vol.360 , pp. 765-773
    • Yan, H.1    Parsons, D.W.2    Jin, G.3
  • 12
    • 0032583387 scopus 로고    scopus 로고
    • Extracting summary statistics to perform meta-analyses of the published literature for survival endpoints
    • M.K. Parmar, V. Torri, and L. Stewart Extracting summary statistics to perform meta-analyses of the published literature for survival endpoints Stat Med 17 1998 2815 2834
    • (1998) Stat Med , vol.17 , pp. 2815-2834
    • Parmar, M.K.1    Torri, V.2    Stewart, L.3
  • 13
    • 84863304598 scopus 로고    scopus 로고
    • R Foundation for Statistical Computing Vienna, Austria ISBN 3-900051-07-0
    • R Development Core Team R: A language and environment for statistical computing 2008 R Foundation for Statistical Computing Vienna, Austria ISBN 3-900051-07-0, URL: http://www.R-project.org
    • (2008) R: A Language and Environment for Statistical Computing
  • 14
    • 84927174399 scopus 로고    scopus 로고
    • Lumley T. Rmeta version 2.10. R package; 2003
    • Lumley T. Rmeta version 2.10. R package; 2003.
  • 15
    • 70349308642 scopus 로고    scopus 로고
    • Low expression of tissue inhibitor of metalloproteinases-1 (TIMP-1) in glioblastoma predicts longer patient survival
    • C. Aaberg-Jessen, K. Christensen, and H. Offenberg Low expression of tissue inhibitor of metalloproteinases-1 (TIMP-1) in glioblastoma predicts longer patient survival J Neurooncol 95 2009 117 128
    • (2009) J Neurooncol , vol.95 , pp. 117-128
    • Aaberg-Jessen, C.1    Christensen, K.2    Offenberg, H.3
  • 16
    • 58149340584 scopus 로고    scopus 로고
    • The incidence, correlation with tumor-infiltrating inflammation, and prognosis of phosphorylated STAT3 expression in human gliomas
    • M. Abou-Ghazal, D.S. Yang, and W. Qiao The incidence, correlation with tumor-infiltrating inflammation, and prognosis of phosphorylated STAT3 expression in human gliomas Clin Cancer Res 14 2008 8228 8235
    • (2008) Clin Cancer Res , vol.14 , pp. 8228-8235
    • Abou-Ghazal, M.1    Yang, D.S.2    Qiao, W.3
  • 17
    • 3042757984 scopus 로고    scopus 로고
    • Immunohistochemical detection of EGFRvIII in high malignancy grade astrocytomas and evaluation of prognostic significance
    • K.D. Aldape, K. Ballman, and A. Furth Immunohistochemical detection of EGFRvIII in high malignancy grade astrocytomas and evaluation of prognostic significance J Neuropathol Exp Neurol 63 2004 700 707
    • (2004) J Neuropathol Exp Neurol , vol.63 , pp. 700-707
    • Aldape, K.D.1    Ballman, K.2    Furth, A.3
  • 18
    • 77949453545 scopus 로고    scopus 로고
    • Polysialic acid neural cell adhesion molecule (PSA-NCAM) is an adverse prognosis factor in glioblastoma, and regulates olig2 expression in glioma cell lines
    • M.-C. Amoureux, B. Coulibaly, and O. Chinot Polysialic acid neural cell adhesion molecule (PSA-NCAM) is an adverse prognosis factor in glioblastoma, and regulates olig2 expression in glioma cell lines BMC Cancer 10 2010 91
    • (2010) BMC Cancer , vol.10 , pp. 91
    • Amoureux, M.-C.1    Coulibaly, B.2    Chinot, O.3
  • 19
    • 0037396295 scopus 로고    scopus 로고
    • Relationship between expression of O6-methylguanine-DNA methyltransferase, glutathione-S-transferase pi in glioblastoma and the survival of the patients treated with nimustine hydrochloride: An immunohistochemical analysis
    • T. Anda, H.K. Shabani, and K. Tsunoda Relationship between expression of O6-methylguanine-DNA methyltransferase, glutathione-S-transferase pi in glioblastoma and the survival of the patients treated with nimustine hydrochloride: an immunohistochemical analysis Neurol Res 25 2003 241 248
    • (2003) Neurol Res , vol.25 , pp. 241-248
    • Anda, T.1    Shabani, H.K.2    Tsunoda, K.3
  • 20
    • 67650073372 scopus 로고    scopus 로고
    • MNS16A minisatellite genotypes in relation to risk of glioma and meningioma and to glioblastoma outcome
    • U. Andersson, P. Osterman, and S. Sjostrom MNS16A minisatellite genotypes in relation to risk of glioma and meningioma and to glioblastoma outcome Int J Cancer 125 2009 968 972
    • (2009) Int J Cancer , vol.125 , pp. 968-972
    • Andersson, U.1    Osterman, P.2    Sjostrom, S.3
  • 21
    • 43949106884 scopus 로고    scopus 로고
    • Monitoring autophagy in glioblastoma with antibody against isoform B of human microtubule-associated protein 1 light chain 3
    • H. Aoki, Y. Kondo, and K. Aldape Monitoring autophagy in glioblastoma with antibody against isoform B of human microtubule-associated protein 1 light chain 3 Autophagy 4 2008 467 475
    • (2008) Autophagy , vol.4 , pp. 467-475
    • Aoki, H.1    Kondo, Y.2    Aldape, K.3
  • 22
    • 36749014033 scopus 로고    scopus 로고
    • Phosphorylated Pak1 level in the cytoplasm correlates with shorter survival time in patients with glioblastoma
    • H. Aoki, T. Yokoyama, and K. Fujiwara Phosphorylated Pak1 level in the cytoplasm correlates with shorter survival time in patients with glioblastoma Clin Cancer Res 13 2007 6603 6609
    • (2007) Clin Cancer Res , vol.13 , pp. 6603-6609
    • Aoki, H.1    Yokoyama, T.2    Fujiwara, K.3
  • 23
    • 17144452027 scopus 로고    scopus 로고
    • Short postoperative survival for glioblastoma patients with a dysfunctional Rb1 pathway in combination with no wild-type PTEN
    • L.M. Backlund, B.R. Nilsson, and H.M. Goike Short postoperative survival for glioblastoma patients with a dysfunctional Rb1 pathway in combination with no wild-type PTEN Clin Cancer Res 9 2003 4151 4158
    • (2003) Clin Cancer Res , vol.9 , pp. 4151-4158
    • Backlund, L.M.1    Nilsson, B.R.2    Goike, H.M.3
  • 24
    • 0032731539 scopus 로고    scopus 로고
    • Loss of chromosome 10 is an independent prognostic factor in high-grade gliomas
    • S. Balesaria, C. Brock, and M. Bower Loss of chromosome 10 is an independent prognostic factor in high-grade gliomas Br J Cancer 81 1999 1371 1377
    • (1999) Br J Cancer , vol.81 , pp. 1371-1377
    • Balesaria, S.1    Brock, C.2    Bower, M.3
  • 25
    • 58149389573 scopus 로고    scopus 로고
    • Association of EGFR c.2073A>T polymorphism with decreased risk of diffusely infiltrating astrocytoma in a Brazilian case-control study. Int
    • K.C. Barbosa, S.M. Oba-Shinjo, and M. Uno Association of EGFR c.2073A>T polymorphism with decreased risk of diffusely infiltrating astrocytoma in a Brazilian case-control study. Int J Biol 23 2008 140 146
    • (2008) J Biol , vol.23 , pp. 140-146
    • Barbosa, K.C.1    Oba-Shinjo, S.M.2    Uno, M.3
  • 26
    • 34250754487 scopus 로고    scopus 로고
    • Cytochrome P450 1B1 expression in glial cell tumors: An immunotherapeutic target
    • J.A. Barnett, D.L. Urbauer, and G.I. Murray Cytochrome P450 1B1 expression in glial cell tumors: an immunotherapeutic target Clin Cancer Res 13 2007 3559 3567
    • (2007) Clin Cancer Res , vol.13 , pp. 3559-3567
    • Barnett, J.A.1    Urbauer, D.L.2    Murray, G.I.3
  • 27
    • 1642453725 scopus 로고    scopus 로고
    • Age-dependent prognostic effects of genetic alterations in glioblastoma
    • T.T. Batchelor, R.A. Betensky, and J.M. Esposito Age-dependent prognostic effects of genetic alterations in glioblastoma Clin Cancer Res 10 2004 228 233
    • (2004) Clin Cancer Res , vol.10 , pp. 228-233
    • Batchelor, T.T.1    Betensky, R.A.2    Esposito, J.M.3
  • 28
    • 0344837730 scopus 로고    scopus 로고
    • Vascular patterns in glioblastoma influence clinical outcome and associate with variable expression of angiogenic proteins: Evidence for distinct angiogenic subtypes
    • P. Birner, M. Piribauer, and I. Fischer Vascular patterns in glioblastoma influence clinical outcome and associate with variable expression of angiogenic proteins: evidence for distinct angiogenic subtypes Brain Pathol 13 2003 133 143
    • (2003) Brain Pathol , vol.13 , pp. 133-143
    • Birner, P.1    Piribauer, M.2    Fischer, I.3
  • 29
    • 0036635227 scopus 로고    scopus 로고
    • Prognostic relevance of p53 protein expression in glioblastoma
    • P. Birner, M. Piribauer, and I. Fischer Prognostic relevance of p53 protein expression in glioblastoma Oncol Rep 9 2002 703 707
    • (2002) Oncol Rep , vol.9 , pp. 703-707
    • Birner, P.1    Piribauer, M.2    Fischer, I.3
  • 30
    • 3042772549 scopus 로고    scopus 로고
    • Correlation of clinical features and methylation status of MGMT gene promoter in glioblastomas
    • J.L. Blanc, M. Wager, and J. Guilhot Correlation of clinical features and methylation status of MGMT gene promoter in glioblastomas J Neurooncol 68 2004 275 283
    • (2004) J Neurooncol , vol.68 , pp. 275-283
    • Blanc, J.L.1    Wager, M.2    Guilhot, J.3
  • 31
    • 77953019788 scopus 로고    scopus 로고
    • The prognostic IDH1(R132) mutation is associated with reduced NADP+-dependent IDH activity in glioblastoma
    • F.E. Bleeker, N.A. Atai, and S. Lamba The prognostic IDH1(R132) mutation is associated with reduced NADP+-dependent IDH activity in glioblastoma Acta Neuropathol 119 2010 487 494
    • (2010) Acta Neuropathol , vol.119 , pp. 487-494
    • Bleeker, F.E.1    Atai, N.A.2    Lamba, S.3
  • 32
    • 68949194091 scopus 로고    scopus 로고
    • No association of (-131C→G) variant of CHI3L1 gene with risk of glioblastoma and prognosis
    • B. Boisselier, Y. Marie, and S. El Hallani No association of (-131C→G) variant of CHI3L1 gene with risk of glioblastoma and prognosis J Neurooncol 94 2009 169 172
    • (2009) J Neurooncol , vol.94 , pp. 169-172
    • Boisselier, B.1    Marie, Y.2    El Hallani, S.3
  • 33
    • 39349085391 scopus 로고    scopus 로고
    • Loss of NOTCH2 positively predicts survival in subgroups of human glial brain tumors
    • J.L. Boulay, A.R. Miserez, and C. Zweifel Loss of NOTCH2 positively predicts survival in subgroups of human glial brain tumors PLoS ONE 2 2007 e576
    • (2007) PLoS ONE , vol.2 , pp. e576
    • Boulay, J.L.1    Miserez, A.R.2    Zweifel, C.3
  • 34
    • 0031727188 scopus 로고    scopus 로고
    • Prognostic significance of Ki67, p53 and epidermal growth factor receptor immunostaining in human glioblastomas
    • C. Bouvier-Labit, O. Chinot, and C. Ochi Prognostic significance of Ki67, p53 and epidermal growth factor receptor immunostaining in human glioblastomas Neuropathol Appl Neurobiol 24 1998 381 388
    • (1998) Neuropathol Appl Neurobiol , vol.24 , pp. 381-388
    • Bouvier-Labit, C.1    Chinot, O.2    Ochi, C.3
  • 35
    • 77952318412 scopus 로고    scopus 로고
    • O(6)-methylguanine DNA-methyltransferase methylation status can change between first surgery for newly diagnosed glioblastoma and second surgery for recurrence: Clinical implications
    • A.A. Brandes, E. Franceschi, and A. Tosoni O(6)-methylguanine DNA-methyltransferase methylation status can change between first surgery for newly diagnosed glioblastoma and second surgery for recurrence: clinical implications Neuro Oncol 12 2010 283 288
    • (2010) Neuro Oncol , vol.12 , pp. 283-288
    • Brandes, A.A.1    Franceschi, E.2    Tosoni, A.3
  • 36
    • 43749094544 scopus 로고    scopus 로고
    • MGMT promoter methylation status can predict the incidence and outcome of pseudoprogression after concomitant radiochemotherapy in newly diagnosed glioblastoma patients
    • A.A. Brandes, E. Franceschi, and A. Tosoni MGMT promoter methylation status can predict the incidence and outcome of pseudoprogression after concomitant radiochemotherapy in newly diagnosed glioblastoma patients J Clin Oncol 26 2008 2192 2197
    • (2008) J Clin Oncol , vol.26 , pp. 2192-2197
    • Brandes, A.A.1    Franceschi, E.2    Tosoni, A.3
  • 37
    • 33644822862 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha-induced protein 3 as a putative regulator of nuclear factor-kappaB-mediated resistance to O6-alkylating agents in human glioblastomas
    • M. Bredel, C. Bredel, and D. Juric Tumor necrosis factor-alpha-induced protein 3 as a putative regulator of nuclear factor-kappaB-mediated resistance to O6-alkylating agents in human glioblastomas J Clin Oncol 24 2006 274 287
    • (2006) J Clin Oncol , vol.24 , pp. 274-287
    • Bredel, M.1    Bredel, C.2    Juric, D.3
  • 38
    • 0036288408 scopus 로고    scopus 로고
    • High expression of DNA topoisomerase II alpha and Ki-67 antigen is associated with prolonged survival in glioblastoma patients
    • M. Bredel, M. Piribauer, and C. Marosi High expression of DNA topoisomerase II alpha and Ki-67 antigen is associated with prolonged survival in glioblastoma patients Eur J Cancer 38 2002 1343 1347
    • (2002) Eur J Cancer , vol.38 , pp. 1343-1347
    • Bredel, M.1    Piribauer, M.2    Marosi, C.3
  • 39
    • 67651039919 scopus 로고    scopus 로고
    • A network model of a cooperative genetic landscape in brain tumors
    • M. Bredel, D.M. Scholtens, and G.R. Harsh A network model of a cooperative genetic landscape in brain tumors JAMA 302 2009 261 275
    • (2009) JAMA , vol.302 , pp. 261-275
    • Bredel, M.1    Scholtens, D.M.2    Harsh, G.R.3
  • 40
    • 34548293704 scopus 로고    scopus 로고
    • Shift in AP-2alpha localization characterizes astrocytoma progression
    • R. Britto, S. Umesh, and A.S. Hegde Shift in AP-2alpha localization characterizes astrocytoma progression Cancer Biol Ther 6 2007 413 418
    • (2007) Cancer Biol Ther , vol.6 , pp. 413-418
    • Britto, R.1    Umesh, S.2    Hegde, A.S.3
  • 41
    • 33645005152 scopus 로고    scopus 로고
    • Inducible cyclooxygenase (COX-2) in glioblastoma-clinical and immunohistochemical (COX-2-VEGF) correlations
    • A.M. Buccoliero, A. Caldarella, and C.F. Gheri Inducible cyclooxygenase (COX-2) in glioblastoma-clinical and immunohistochemical (COX-2-VEGF) correlations Clin Neuropathol 25 2006 59 66
    • (2006) Clin Neuropathol , vol.25 , pp. 59-66
    • Buccoliero, A.M.1    Caldarella, A.2    Gheri, C.F.3
  • 42
    • 0036828260 scopus 로고    scopus 로고
    • Genetic aberrations defined by comparative genomic hybridization distinguish long-term from typical survivors of glioblastoma
    • E.C. Burton, K.R. Lamborn, and B.G. Feuerstein Genetic aberrations defined by comparative genomic hybridization distinguish long-term from typical survivors of glioblastoma Cancer Res 62 2002 6205 6210
    • (2002) Cancer Res , vol.62 , pp. 6205-6210
    • Burton, E.C.1    Lamborn, K.R.2    Feuerstein, B.G.3
  • 43
    • 0036154755 scopus 로고    scopus 로고
    • Aberrant p53, mdm2, and proliferation differ in glioblastomas from long-term compared with typical survivors
    • E.C. Burton, K.R. Lamborn, and P. Forsyth Aberrant p53, mdm2, and proliferation differ in glioblastomas from long-term compared with typical survivors Clin Cancer Res 8 2002 180 187
    • (2002) Clin Cancer Res , vol.8 , pp. 180-187
    • Burton, E.C.1    Lamborn, K.R.2    Forsyth, P.3
  • 44
    • 70350314719 scopus 로고    scopus 로고
    • The correlation and prognostic significance of MGMT promoter methylation and MGMT protein in glioblastomas
    • [discussion 875]
    • V.T. Cao, T.Y. Jung, and S. Jung The correlation and prognostic significance of MGMT promoter methylation and MGMT protein in glioblastomas Neurosurgery 65 2009 866 875 [discussion 875]
    • (2009) Neurosurgery , vol.65 , pp. 866-875
    • Cao, V.T.1    Jung, T.Y.2    Jung, S.3
  • 45
    • 38149046589 scopus 로고    scopus 로고
    • Pitfalls in the assessment of MGMT expression and in its correlation with survival in diffuse astrocytomas: Proposal of a feasible immunohistochemical approach
    • D. Capper, M. Mittelbronn, and R. Meyermann Pitfalls in the assessment of MGMT expression and in its correlation with survival in diffuse astrocytomas: proposal of a feasible immunohistochemical approach Acta Neuropathol 115 2008 249 259
    • (2008) Acta Neuropathol , vol.115 , pp. 249-259
    • Capper, D.1    Mittelbronn, M.2    Meyermann, R.3
  • 46
    • 34249014416 scopus 로고    scopus 로고
    • Relationship between survival and edema in malignant gliomas: Role of vascular endothelial growth factor and neuronal pentraxin 2
    • M.R. Carlson, W.B. Pope, and S. Horvath Relationship between survival and edema in malignant gliomas: role of vascular endothelial growth factor and neuronal pentraxin 2 Clin Cancer Res 13 2007 2592 2598
    • (2007) Clin Cancer Res , vol.13 , pp. 2592-2598
    • Carlson, M.R.1    Pope, W.B.2    Horvath, S.3
  • 47
    • 33748772846 scopus 로고    scopus 로고
    • Polymorphism in Sp1 recognition site of the EGF receptor gene promoter and risk of glioblastoma
    • C. Carpentier, F. Laigle-Donadey, and Y. Marie Polymorphism in Sp1 recognition site of the EGF receptor gene promoter and risk of glioblastoma Neurology 67 2006 872 874
    • (2006) Neurology , vol.67 , pp. 872-874
    • Carpentier, C.1    Laigle-Donadey, F.2    Marie, Y.3
  • 48
    • 34547180820 scopus 로고    scopus 로고
    • Association of telomerase gene hTERT polymorphism and malignant gliomas
    • C. Carpentier, J. Lejeune, and F. Gros Association of telomerase gene hTERT polymorphism and malignant gliomas J Neurooncol 84 2007 249 253
    • (2007) J Neurooncol , vol.84 , pp. 249-253
    • Carpentier, C.1    Lejeune, J.2    Gros, F.3
  • 49
    • 0037087706 scopus 로고    scopus 로고
    • The expression of a new variant of the pro-apoptotic molecule Bax, Baxpsi, is correlated with an increased survival of glioblastoma multiforme patients
    • P.F. Cartron, L. Oliver, and S. Martin The expression of a new variant of the pro-apoptotic molecule Bax, Baxpsi, is correlated with an increased survival of glioblastoma multiforme patients Hum Mol Genet 11 2002 675 687
    • (2002) Hum Mol Genet , vol.11 , pp. 675-687
    • Cartron, P.F.1    Oliver, L.2    Martin, S.3
  • 50
    • 0034886306 scopus 로고    scopus 로고
    • Prognostic and pathologic significance of quantitative protein expression profiling in human gliomas
    • A. Chakravarti, M.A. Delaney, and E. Noll Prognostic and pathologic significance of quantitative protein expression profiling in human gliomas Clin Cancer Res 7 2001 2387 2395
    • (2001) Clin Cancer Res , vol.7 , pp. 2387-2395
    • Chakravarti, A.1    Delaney, M.A.2    Noll, E.3
  • 51
    • 0037083317 scopus 로고    scopus 로고
    • Quantitatively determined survivin expression levels are of prognostic value in human gliomas
    • A. Chakravarti, E. Noll, and P.M. Black Quantitatively determined survivin expression levels are of prognostic value in human gliomas J Clin Oncol 20 2002 1063 1068
    • (2002) J Clin Oncol , vol.20 , pp. 1063-1068
    • Chakravarti, A.1    Noll, E.2    Black, P.M.3
  • 52
    • 18944393158 scopus 로고    scopus 로고
    • Immunohistochemically determined total epidermal growth factor receptor levels not of prognostic value in newly diagnosed glioblastoma multiforme: Report from the Radiation Therapy Oncology Group
    • A. Chakravarti, W. Seiferheld, and X. Tu Immunohistochemically determined total epidermal growth factor receptor levels not of prognostic value in newly diagnosed glioblastoma multiforme: report from the Radiation Therapy Oncology Group Int J Radiat Oncol Biol Phys 62 2005 318 327
    • (2005) Int J Radiat Oncol Biol Phys , vol.62 , pp. 318-327
    • Chakravarti, A.1    Seiferheld, W.2    Tu, X.3
  • 53
    • 3042823868 scopus 로고    scopus 로고
    • The prognostic significance of phosphatidylinositol 3-kinase pathway activation in human gliomas
    • A. Chakravarti, G. Zhai, and Y. Suzuki The prognostic significance of phosphatidylinositol 3-kinase pathway activation in human gliomas J Clin Oncol 22 2004 1926 1933
    • (2004) J Clin Oncol , vol.22 , pp. 1926-1933
    • Chakravarti, A.1    Zhai, G.2    Suzuki, Y.3
  • 54
    • 33746136947 scopus 로고    scopus 로고
    • Association of mutant TP53 with alternative lengthening of telomeres and favorable prognosis in glioma
    • Y.J. Chen, V. Hakin-Smith, and M. Teo Association of mutant TP53 with alternative lengthening of telomeres and favorable prognosis in glioma Cancer Res 66 2006 6473 6476
    • (2006) Cancer Res , vol.66 , pp. 6473-6476
    • Chen, Y.J.1    Hakin-Smith, V.2    Teo, M.3
  • 55
    • 0032587774 scopus 로고    scopus 로고
    • Relationship between O6-methylguanine-DNA methyltransferase levels and clinical response induced by chloroethylnitrosourea therapy in glioma patients
    • Z.P. Chen, D. Yarosh, and Y. Garcia Relationship between O6-methylguanine-DNA methyltransferase levels and clinical response induced by chloroethylnitrosourea therapy in glioma patients Can J Neurol Sci 26 1999 104 109
    • (1999) Can J Neurol Sci , vol.26 , pp. 104-109
    • Chen, Z.P.1    Yarosh, D.2    Garcia, Y.3
  • 56
    • 53549099123 scopus 로고    scopus 로고
    • The prognostic value of nestin expression in newly diagnosed glioblastoma: Report from the Radiation Therapy Oncology Group
    • P. Chinnaiyan, M. Wang, and A.M. Rojiani The prognostic value of nestin expression in newly diagnosed glioblastoma: report from the Radiation Therapy Oncology Group Radiat Oncol 3 2008 32
    • (2008) Radiat Oncol , vol.3 , pp. 32
    • Chinnaiyan, P.1    Wang, M.2    Rojiani, A.M.3
  • 57
    • 34248198326 scopus 로고    scopus 로고
    • Correlation between O6-methylguanine-DNA methyltransferase and survival in inoperable newly diagnosed glioblastoma patients treated with neoadjuvant temozolomide
    • O.L. Chinot, M. Barrie, and S. Fuentes Correlation between O6-methylguanine-DNA methyltransferase and survival in inoperable newly diagnosed glioblastoma patients treated with neoadjuvant temozolomide J Clin Oncol 25 2007 1470 1475
    • (2007) J Clin Oncol , vol.25 , pp. 1470-1475
    • Chinot, O.L.1    Barrie, M.2    Fuentes, S.3
  • 58
    • 0036715324 scopus 로고    scopus 로고
    • Active matrix metalloproteinase 9 expression is associated with primary glioblastoma subtype
    • G. Choe, J.K. Park, and L. Jouben-Steele Active matrix metalloproteinase 9 expression is associated with primary glioblastoma subtype Clin Cancer Res 8 2002 2894 2901
    • (2002) Clin Cancer Res , vol.8 , pp. 2894-2901
    • Choe, G.1    Park, J.K.2    Jouben-Steele, L.3
  • 59
    • 53349174906 scopus 로고    scopus 로고
    • CD133 identifies perivascular niches in grade II-IV astrocytomas
    • K. Christensen, H.D. Schroder, and B.W. Kristensen CD133 identifies perivascular niches in grade II-IV astrocytomas J Neurooncol 90 2008 157 170
    • (2008) J Neurooncol , vol.90 , pp. 157-170
    • Christensen, K.1    Schroder, H.D.2    Kristensen, B.W.3
  • 60
    • 75749115909 scopus 로고    scopus 로고
    • A multigene predictor of outcome in glioblastoma
    • H. Colman, L. Zhang, and E.P. Sulman A multigene predictor of outcome in glioblastoma Neuro Oncol 12 2009 49 57
    • (2009) Neuro Oncol , vol.12 , pp. 49-57
    • Colman, H.1    Zhang, L.2    Sulman, E.P.3
  • 61
    • 34249104304 scopus 로고    scopus 로고
    • Association between functional EGF+61 polymorphism and glioma risk
    • B.M. Costa, P. Ferreira, and S. Costa Association between functional EGF+61 polymorphism and glioma risk Clin Cancer Res 13 2007 2621 2626
    • (2007) Clin Cancer Res , vol.13 , pp. 2621-2626
    • Costa, B.M.1    Ferreira, P.2    Costa, S.3
  • 62
    • 76549121309 scopus 로고    scopus 로고
    • Reversing HOXA9 oncogene activation by PI3K inhibition: Epigenetic mechanism and prognostic significance in human glioblastoma
    • B.M. Costa, J.S. Smith, and Y. Chen Reversing HOXA9 oncogene activation by PI3K inhibition: epigenetic mechanism and prognostic significance in human glioblastoma Cancer Res 70 2010 453 462
    • (2010) Cancer Res , vol.70 , pp. 453-462
    • Costa, B.M.1    Smith, J.S.2    Chen, Y.3
  • 63
    • 77951966345 scopus 로고    scopus 로고
    • Epidermal growth factor receptor in glioblastomas: Correlation between gene copy number and protein expression
    • B. Coulibaly, I. Nanni, and B. Quilichini Epidermal growth factor receptor in glioblastomas: correlation between gene copy number and protein expression Hum Pathol 41 2010 815 823
    • (2010) Hum Pathol , vol.41 , pp. 815-823
    • Coulibaly, B.1    Nanni, I.2    Quilichini, B.3
  • 64
    • 34249053906 scopus 로고    scopus 로고
    • MGMT prognostic impact on glioblastoma is dependent on therapeutic modalities
    • E. Criniere, G. Kaloshi, and F. Laigle-Donadey MGMT prognostic impact on glioblastoma is dependent on therapeutic modalities J Neurooncol 83 2007 173 179
    • (2007) J Neurooncol , vol.83 , pp. 173-179
    • Criniere, E.1    Kaloshi, G.2    Laigle-Donadey, F.3
  • 65
    • 0036125118 scopus 로고    scopus 로고
    • Association of elevated glial expression of interleukin-1beta with improved survival in patients with glioblastomas multiforme
    • E. Cuny, H. Loiseau, and G. Penchet Association of elevated glial expression of interleukin-1beta with improved survival in patients with glioblastomas multiforme J Neurosurg 96 2002 294 301
    • (2002) J Neurosurg , vol.96 , pp. 294-301
    • Cuny, E.1    Loiseau, H.2    Penchet, G.3
  • 66
    • 53049104285 scopus 로고    scopus 로고
    • P53-independent mechanisms regulate the P2-MDM2 promoter in adult astrocytic tumours
    • M. Dimitriadi, G. Poulogiannis, and L. Liu P53-independent mechanisms regulate the P2-MDM2 promoter in adult astrocytic tumours Br J Cancer 99 2008 1144 1152
    • (2008) Br J Cancer , vol.99 , pp. 1144-1152
    • Dimitriadi, M.1    Poulogiannis, G.2    Liu, L.3
  • 67
    • 34447534387 scopus 로고    scopus 로고
    • Prognostic implication of clinical and pathologic features in patients with glioblastoma multiforme treated with concomitant radiation plus temozolomide
    • V. Donato, A. Papaleo, and A. Castrichino Prognostic implication of clinical and pathologic features in patients with glioblastoma multiforme treated with concomitant radiation plus temozolomide Tumori 93 2007 248 256
    • (2007) Tumori , vol.93 , pp. 248-256
    • Donato, V.1    Papaleo, A.2    Castrichino, A.3
  • 68
    • 60549085031 scopus 로고    scopus 로고
    • TP53 codon 72 polymorphism is associated with age at onset of glioblastoma
    • S. El Hallani, F. Ducray, and A. Idbaih TP53 codon 72 polymorphism is associated with age at onset of glioblastoma Neurology 72 2009 332 336
    • (2009) Neurology , vol.72 , pp. 332-336
    • El Hallani, S.1    Ducray, F.2    Idbaih, A.3
  • 69
    • 36348978710 scopus 로고    scopus 로고
    • No association of MDM2 SNP309 with risk of glioblastoma and prognosis
    • S. El Hallani, Y. Marie, and A. Idbaih No association of MDM2 SNP309 with risk of glioblastoma and prognosis J Neurooncol 85 2007 241 244
    • (2007) J Neurooncol , vol.85 , pp. 241-244
    • El Hallani, S.1    Marie, Y.2    Idbaih, A.3
  • 70
    • 34249021494 scopus 로고    scopus 로고
    • Methylation of O6-methylguanine DNA methyltransferase and loss of heterozygosity on 19q and/or 17p are overlapping features of secondary glioblastomas with prolonged survival
    • M. Eoli, F. Menghi, and M.G. Bruzzone Methylation of O6-methylguanine DNA methyltransferase and loss of heterozygosity on 19q and/or 17p are overlapping features of secondary glioblastomas with prolonged survival Clin Cancer Res 13 2007 2606 2613
    • (2007) Clin Cancer Res , vol.13 , pp. 2606-2613
    • Eoli, M.1    Menghi, F.2    Bruzzone, M.G.3
  • 71
    • 0036094711 scopus 로고    scopus 로고
    • Dysregulation of PTEN and protein kinase B is associated with glioma histology and patient survival
    • R.P. Ermoian, C.S. Furniss, and K.R. Lamborn Dysregulation of PTEN and protein kinase B is associated with glioma histology and patient survival Clin Cancer Res 8 2002 1100 1106
    • (2002) Clin Cancer Res , vol.8 , pp. 1100-1106
    • Ermoian, R.P.1    Furniss, C.S.2    Lamborn, K.R.3
  • 72
    • 70350741358 scopus 로고    scopus 로고
    • Genomic and expression profiling of glioblastoma stem cell-like spheroid cultures identifies novel tumor-relevant genes associated with survival
    • A. Ernst, S. Hofmann, and R. Ahmadi Genomic and expression profiling of glioblastoma stem cell-like spheroid cultures identifies novel tumor-relevant genes associated with survival Clin Cancer Res 15 2009 6541 6550
    • (2009) Clin Cancer Res , vol.15 , pp. 6541-6550
    • Ernst, A.1    Hofmann, S.2    Ahmadi, R.3
  • 73
    • 0033772980 scopus 로고    scopus 로고
    • Bcl-2 expression in higher-grade human glioma: A clinical and experimental study
    • C. Fels, C. Schafer, and B. Huppe Bcl-2 expression in higher-grade human glioma: a clinical and experimental study J Neurooncol 48 2000 207 216
    • (2000) J Neurooncol , vol.48 , pp. 207-216
    • Fels, C.1    Schafer, C.2    Huppe, B.3
  • 74
    • 33745918920 scopus 로고    scopus 로고
    • Cathepsin S expression: An independent prognostic factor in glioblastoma tumours-A pilot study
    • T. Flannery, S. McQuaid, and C. McGoohan Cathepsin S expression: an independent prognostic factor in glioblastoma tumours-A pilot study Int J Cancer 119 2006 854 860
    • (2006) Int J Cancer , vol.119 , pp. 854-860
    • Flannery, T.1    McQuaid, S.2    McGoohan, C.3
  • 75
    • 72449164564 scopus 로고    scopus 로고
    • Tumor necrosis factor-like weak inducer of apoptosis stimulation of glioma cell survival is dependent on Akt2 function
    • S.P. Fortin, M.J. Ennis, and B.A. Savitch Tumor necrosis factor-like weak inducer of apoptosis stimulation of glioma cell survival is dependent on Akt2 function Mol Cancer Res 7 2009 1871 1881
    • (2009) Mol Cancer Res , vol.7 , pp. 1871-1881
    • Fortin, S.P.1    Ennis, M.J.2    Savitch, B.A.3
  • 76
    • 0036679232 scopus 로고    scopus 로고
    • Apoptosis and survival in high-grade astrocytomas as related to tumor Fas (APO-1/CD95) expression
    • B. Frankel, S.L. Longo, and C. Leach Apoptosis and survival in high-grade astrocytomas as related to tumor Fas (APO-1/CD95) expression J Neurooncol 59 2002 27 34
    • (2002) J Neurooncol , vol.59 , pp. 27-34
    • Frankel, B.1    Longo, S.L.2    Leach, C.3
  • 78
    • 14644396175 scopus 로고    scopus 로고
    • Promoter hypermethylation of mismatch repair gene hMLH1 predicts the clinical response of malignant astrocytomas to nitrosourea
    • T. Fukushima, Y. Katayama, and T. Watanabe Promoter hypermethylation of mismatch repair gene hMLH1 predicts the clinical response of malignant astrocytomas to nitrosourea Clin Cancer Res 11 2005 1539 1544
    • (2005) Clin Cancer Res , vol.11 , pp. 1539-1544
    • Fukushima, T.1    Katayama, Y.2    Watanabe, T.3
  • 79
    • 55949088546 scopus 로고    scopus 로고
    • Cell cycle times of short-term cultures of brain cancers as predictors of survival
    • C.E. Furneaux, E.S. Marshall, and K. Yeoh Cell cycle times of short-term cultures of brain cancers as predictors of survival Br J Cancer 99 2008 1678 1683
    • (2008) Br J Cancer , vol.99 , pp. 1678-1683
    • Furneaux, C.E.1    Marshall, E.S.2    Yeoh, K.3
  • 80
    • 76749106058 scopus 로고    scopus 로고
    • Three-dimensional nuclear telomere architecture is associated with differential time to progression and overall survival in glioblastoma patients
    • M. Gadji, D. Fortin, and A.-M. Tsanaclis Three-dimensional nuclear telomere architecture is associated with differential time to progression and overall survival in glioblastoma patients Neoplasia 12 2010 183 191
    • (2010) Neoplasia , vol.12 , pp. 183-191
    • Gadji, M.1    Fortin, D.2    Tsanaclis, A.-M.3
  • 81
    • 77950855517 scopus 로고    scopus 로고
    • Expression of the transcription factor HEY1 in glioblastoma: A preliminary clinical study
    • P. Gaetani, E. Hulleman, and D. Levi Expression of the transcription factor HEY1 in glioblastoma: a preliminary clinical study Tumori 96 2010 97 102
    • (2010) Tumori , vol.96 , pp. 97-102
    • Gaetani, P.1    Hulleman, E.2    Levi, D.3
  • 82
    • 0031671411 scopus 로고    scopus 로고
    • Gene amplification as a prognostic factor in primary and secondary high-grade malignant gliomas
    • E. Galanis, J. Buckner, and D. Kimmel Gene amplification as a prognostic factor in primary and secondary high-grade malignant gliomas Int J Oncol 13 1998 717 724
    • (1998) Int J Oncol , vol.13 , pp. 717-724
    • Galanis, E.1    Buckner, J.2    Kimmel, D.3
  • 83
    • 33750044651 scopus 로고    scopus 로고
    • Increased expression of pituitary tumor-transforming gene (PTTG)-1 is correlated with poor prognosis in glioma patients
    • N. Genkai, J. Homma, and M. Sano Increased expression of pituitary tumor-transforming gene (PTTG)-1 is correlated with poor prognosis in glioma patients Oncol Rep 15 2006 1569 1574
    • (2006) Oncol Rep , vol.15 , pp. 1569-1574
    • Genkai, N.1    Homma, J.2    Sano, M.3
  • 84
    • 70449440499 scopus 로고    scopus 로고
    • Mgmt methylation is a prognostic biomarker in elderly patients with newly diagnosed glioblastoma
    • E.R. Gerstner, S. Yip, and D.L. Wang Mgmt methylation is a prognostic biomarker in elderly patients with newly diagnosed glioblastoma Neurology 73 2009 1509 1510
    • (2009) Neurology , vol.73 , pp. 1509-1510
    • Gerstner, E.R.1    Yip, S.2    Wang, D.L.3
  • 85
    • 77649259296 scopus 로고    scopus 로고
    • MicroRNA-451 regulates LKB1/AMPK signaling and allows adaptation to metabolic stress in glioma cells
    • J. Godlewski, M.O. Nowicki, and A. Bronisz MicroRNA-451 regulates LKB1/AMPK signaling and allows adaptation to metabolic stress in glioma cells Mol Cell 37 2010 620 632
    • (2010) Mol Cell , vol.37 , pp. 620-632
    • Godlewski, J.1    Nowicki, M.O.2    Bronisz, A.3
  • 86
    • 37449003812 scopus 로고    scopus 로고
    • Nomograms for predicting survival of patients with newly diagnosed glioblastoma: Prognostic factor analysis of EORTC and NCIC trial 26981-22981/CE.3
    • T. Gorlia, M.J. van den Bent, and M.E. Hegi Nomograms for predicting survival of patients with newly diagnosed glioblastoma: prognostic factor analysis of EORTC and NCIC trial 26981-22981/CE.3 Lancet Oncol 9 2008 29 38
    • (2008) Lancet Oncol , vol.9 , pp. 29-38
    • Gorlia, T.1    Van Den Bent, M.J.2    Hegi, M.E.3
  • 87
    • 71549126830 scopus 로고    scopus 로고
    • Intrinsic gene expression profiles of gliomas are a better predictor of survival than histology
    • L.A.M. Gravendeel, M.C.M. Kouwenhoven, and O. Gevaert Intrinsic gene expression profiles of gliomas are a better predictor of survival than histology Cancer Res 69 2009 9065 9072
    • (2009) Cancer Res , vol.69 , pp. 9065-9072
    • Gravendeel, L.A.M.1    Kouwenhoven, M.C.M.2    Gevaert, O.3
  • 88
    • 33751242487 scopus 로고    scopus 로고
    • Increased expression of thymidylate synthetase (TS), ubiquitin specific protease 10 (USP10) and survivin is associated with poor survival in glioblastoma multiforme (GBM)
    • J.M. Grunda, L.B. Nabors, and C.A. Palmer Increased expression of thymidylate synthetase (TS), ubiquitin specific protease 10 (USP10) and survivin is associated with poor survival in glioblastoma multiforme (GBM) J Neurooncol 80 2006 261 274
    • (2006) J Neurooncol , vol.80 , pp. 261-274
    • Grunda, J.M.1    Nabors, L.B.2    Palmer, C.A.3
  • 89
    • 0033816571 scopus 로고    scopus 로고
    • Correlation of tumor p53 and PCNA with response and survival of glioblastoma in patients treated with an ECOG protocol of pre-irradiation chemotherapy
    • M.L. Grunnet, A. O'Neill, and M. Gilbert Correlation of tumor p53 and PCNA with response and survival of glioblastoma in patients treated with an ECOG protocol of pre-irradiation chemotherapy Clin Neuropathol 19 2000 230 234
    • (2000) Clin Neuropathol , vol.19 , pp. 230-234
    • Grunnet, M.L.1    O'Neill, A.2    Gilbert, M.3
  • 90
    • 44849109087 scopus 로고    scopus 로고
    • Fascin expression [corrected] in glial tumors and its prognostic significance in glioblastomas
    • A. Gunal, O. Onguru, and M. Safali Fascin expression [corrected] in glial tumors and its prognostic significance in glioblastomas Neuropathology 28 2008 382 386
    • (2008) Neuropathology , vol.28 , pp. 382-386
    • Gunal, A.1    Onguru, O.2    Safali, M.3
  • 91
    • 34547436997 scopus 로고    scopus 로고
    • Carbonic anhydrase II in the endothelium of glial tumors: A potential target for therapy
    • J. Haapasalo, K. Nordfors, and S. Jarvela Carbonic anhydrase II in the endothelium of glial tumors: a potential target for therapy Neuro Oncol 9 2007 308 313
    • (2007) Neuro Oncol , vol.9 , pp. 308-313
    • Haapasalo, J.1    Nordfors, K.2    Jarvela, S.3
  • 92
    • 31544475474 scopus 로고    scopus 로고
    • Expression of carbonic anhydrase IX in astrocytic tumors predicts poor prognosis
    • J.A. Haapasalo, K.M. Nordfors, and M. Hilvo Expression of carbonic anhydrase IX in astrocytic tumors predicts poor prognosis Clin Cancer Res 12 2006 473 477
    • (2006) Clin Cancer Res , vol.12 , pp. 473-477
    • Haapasalo, J.A.1    Nordfors, K.M.2    Hilvo, M.3
  • 93
    • 31144441457 scopus 로고    scopus 로고
    • Immunohistochemical analysis of platelet-derived growth factor receptor-alpha, -beta, c-kit, c-abl, and arg proteins in glioblastoma: Possible implications for patient selection for imatinib mesylate therapy
    • C. Haberler, E. Gelpi, and C. Marosi Immunohistochemical analysis of platelet-derived growth factor receptor-alpha, -beta, c-kit, c-abl, and arg proteins in glioblastoma: possible implications for patient selection for imatinib mesylate therapy J Neurooncol 76 2006 105 109
    • (2006) J Neurooncol , vol.76 , pp. 105-109
    • Haberler, C.1    Gelpi, E.2    Marosi, C.3
  • 94
    • 0037426088 scopus 로고    scopus 로고
    • Alternative lengthening of telomeres and survival in patients with glioblastoma multiforme
    • V. Hakin-Smith, D.A. Jellinek, and D. Levy Alternative lengthening of telomeres and survival in patients with glioblastoma multiforme Lancet 361 2003 836 838
    • (2003) Lancet , vol.361 , pp. 836-838
    • Hakin-Smith, V.1    Jellinek, D.A.2    Levy, D.3
  • 95
    • 0033493770 scopus 로고    scopus 로고
    • Analysis of proliferation and apoptosis in brain gliomas: Prognostic and clinical value
    • M.A. Heesters, J. Koudstaal, and K.G. Go Analysis of proliferation and apoptosis in brain gliomas: prognostic and clinical value J Neurooncol 44 1999 255 266
    • (1999) J Neurooncol , vol.44 , pp. 255-266
    • Heesters, M.A.1    Koudstaal, J.2    Go, K.G.3
  • 96
    • 20044372154 scopus 로고    scopus 로고
    • MGMT gene silencing and benefit from temozolomide in glioblastoma
    • M.E. Hegi MGMT gene silencing and benefit from temozolomide in glioblastoma N Engl J Med 352 2005 10
    • (2005) N Engl J Med , vol.352 , pp. 10
    • Hegi, M.E.1
  • 97
    • 52649169692 scopus 로고    scopus 로고
    • Incidence and prognostic impact of FoxP3+ regulatory T cells in human gliomas
    • A.B. Heimberger, M. Abou-Ghazal, and C. Reina-Ortiz Incidence and prognostic impact of FoxP3+ regulatory T cells in human gliomas Clin Cancer Res 14 2008 5166 5172
    • (2008) Clin Cancer Res , vol.14 , pp. 5166-5172
    • Heimberger, A.B.1    Abou-Ghazal, M.2    Reina-Ortiz, C.3
  • 98
    • 14644412873 scopus 로고    scopus 로고
    • Prognostic effect of epidermal growth factor receptor and EGFRvIII in glioblastoma multiforme patients
    • A.B. Heimberger, R. Hlatky, and D. Suki Prognostic effect of epidermal growth factor receptor and EGFRvIII in glioblastoma multiforme patients Clin Cancer Res 11 2005 1462 1466
    • (2005) Clin Cancer Res , vol.11 , pp. 1462-1466
    • Heimberger, A.B.1    Hlatky, R.2    Suki, D.3
  • 99
    • 0032915057 scopus 로고    scopus 로고
    • C-myc oncogene family expression in glioblastoma and survival
    • J.W. Herms, F.D. von Loewenich, and J. Behnke C-myc oncogene family expression in glioblastoma and survival Surg Neurol 51 1999 536 542
    • (1999) Surg Neurol , vol.51 , pp. 536-542
    • Herms, J.W.1    Von Loewenich, F.D.2    Behnke, J.3
  • 100
    • 66149167311 scopus 로고    scopus 로고
    • Folate supplementation limits the aggressiveness of glioma via the remethylation of DNA repeats element and genes governing apoptosis and proliferation
    • E. Hervouet, E. Debien, and L. Campion Folate supplementation limits the aggressiveness of glioma via the remethylation of DNA repeats element and genes governing apoptosis and proliferation Clin Cancer Res 15 2009 3519 3529
    • (2009) Clin Cancer Res , vol.15 , pp. 3519-3529
    • Hervouet, E.1    Debien, E.2    Campion, L.3
  • 101
    • 0347686127 scopus 로고    scopus 로고
    • Genetic markers in glioblastoma: Prognostic significance and future therapeutic implications
    • C. Hill, S.B. Hunter, and D.J. Brat Genetic markers in glioblastoma: prognostic significance and future therapeutic implications Adv Anat Pathol 10 2003 212 217
    • (2003) Adv Anat Pathol , vol.10 , pp. 212-217
    • Hill, C.1    Hunter, S.B.2    Brat, D.J.3
  • 102
    • 3042682951 scopus 로고    scopus 로고
    • Histological indicators of prognosis in glioblastomas: Retinoblastoma protein expression and oligodendroglial differentiation indicate improved survival
    • D.A. Hilton, M. Penney, and L. Pobereskin Histological indicators of prognosis in glioblastomas: retinoblastoma protein expression and oligodendroglial differentiation indicate improved survival Histopathology 44 2004 555 560
    • (2004) Histopathology , vol.44 , pp. 555-560
    • Hilton, D.A.1    Penney, M.2    Pobereskin, L.3
  • 103
    • 0032523944 scopus 로고    scopus 로고
    • Telomerase activity and alterations in telomere length in human brain tumors
    • S. Hiraga, T. Ohnishi, and S. Izumoto Telomerase activity and alterations in telomere length in human brain tumors Cancer Res 58 1998 2117 2125
    • (1998) Cancer Res , vol.58 , pp. 2117-2125
    • Hiraga, S.1    Ohnishi, T.2    Izumoto, S.3
  • 104
    • 0032402184 scopus 로고    scopus 로고
    • Immunohistochemical analysis of metallothionein in astrocytic tumors in relation to tumor grade, proliferative potential, and survival
    • T. Hiura, H. Khalid, and H. Yamashita Immunohistochemical analysis of metallothionein in astrocytic tumors in relation to tumor grade, proliferative potential, and survival Cancer 83 1998 2361 2369
    • (1998) Cancer , vol.83 , pp. 2361-2369
    • Hiura, T.1    Khalid, H.2    Yamashita, H.3
  • 105
    • 85047688890 scopus 로고    scopus 로고
    • MIB-1 and DNA topoisomerase II alpha could be helpful for predicting long-term survival of patients with glioblastoma
    • D.M.T. Ho, C.Y. Hsu, and L.T. Ting MIB-1 and DNA topoisomerase II alpha could be helpful for predicting long-term survival of patients with glioblastoma Am J Clin Pathol 119 2003 715 722
    • (2003) Am J Clin Pathol , vol.119 , pp. 715-722
    • Ho, D.M.T.1    Hsu, C.Y.2    Ting, L.T.3
  • 106
    • 33748533494 scopus 로고    scopus 로고
    • Correlation among pathology, genotype, and patient outcomes in glioblastoma
    • T. Homma, T. Fukushima, and S. Vaccarella Correlation among pathology, genotype, and patient outcomes in glioblastoma J Neuropathol Exp Neurol 65 2006 846 854
    • (2006) J Neuropathol Exp Neurol , vol.65 , pp. 846-854
    • Homma, T.1    Fukushima, T.2    Vaccarella, S.3
  • 107
    • 0032722750 scopus 로고    scopus 로고
    • Loss of chromosome 10 in glioblastoma: Relation to proliferation and angiogenesis
    • H. Horiguchi, T. Hirose, and T. Sano Loss of chromosome 10 in glioblastoma: relation to proliferation and angiogenesis Pathol Int 49 1999 681 686
    • (1999) Pathol Int , vol.49 , pp. 681-686
    • Horiguchi, H.1    Hirose, T.2    Sano, T.3
  • 108
    • 33751208636 scopus 로고    scopus 로고
    • Analysis of oncogenic signaling networks in glioblastoma identifies ASPM as a molecular target
    • S. Horvath, B. Zhang, and M. Carlson Analysis of oncogenic signaling networks in glioblastoma identifies ASPM as a molecular target Proc Natl Acad Sci U S A 103 2006 17402 17407
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 17402-17407
    • Horvath, S.1    Zhang, B.2    Carlson, M.3
  • 109
    • 33646379132 scopus 로고    scopus 로고
    • Prognostic impact of molecular markers in a series of 220 primary glioblastomas
    • C. Houillier, J. Lejeune, and A. Benouaich-Amiel Prognostic impact of molecular markers in a series of 220 primary glioblastomas Cancer 106 2006 2218 2223
    • (2006) Cancer , vol.106 , pp. 2218-2223
    • Houillier, C.1    Lejeune, J.2    Benouaich-Amiel, A.3
  • 110
    • 58649120268 scopus 로고    scopus 로고
    • A role for the transcription factor HEY1 in glioblastoma
    • E. Hulleman, M. Quarto, and R. Vernell A role for the transcription factor HEY1 in glioblastoma J Cell Mol Med 13 2009 136 146
    • (2009) J Cell Mol Med , vol.13 , pp. 136-146
    • Hulleman, E.1    Quarto, M.2    Vernell, R.3
  • 111
    • 0142244766 scopus 로고    scopus 로고
    • Prognostic significance of annexin VII expression in glioblastomas multiforme in humans
    • K.S. Hung, and S.L. Howng Prognostic significance of annexin VII expression in glioblastomas multiforme in humans J Neurosurg 99 2003 886 892
    • (2003) J Neurosurg , vol.99 , pp. 886-892
    • Hung, K.S.1    Howng, S.L.2
  • 112
    • 40749123639 scopus 로고    scopus 로고
    • Axl and growth arrest-specific gene 6 are frequently overexpressed in human gliomas and predict poor prognosis in patients with glioblastoma multiforme
    • M. Hutterer, P. Knyazev, and A. Abate Axl and growth arrest-specific gene 6 are frequently overexpressed in human gliomas and predict poor prognosis in patients with glioblastoma multiforme Clin Cancer Res 14 2008 130 138
    • (2008) Clin Cancer Res , vol.14 , pp. 130-138
    • Hutterer, M.1    Knyazev, P.2    Abate, A.3
  • 113
    • 0032193270 scopus 로고    scopus 로고
    • Prognostic evaluation in supratentorial astrocytic tumors using p53, epidermal growth factor receptor, c-erbB-2 immunostaining
    • S.L. Hwang, Y.R. Hong, and C.Y. Chai Prognostic evaluation in supratentorial astrocytic tumors using p53, epidermal growth factor receptor, c-erbB-2 immunostaining Kaohsiung J Med Sci 14 1998 607 615
    • (1998) Kaohsiung J Med Sci , vol.14 , pp. 607-615
    • Hwang, S.L.1    Hong, Y.R.2    Chai, C.Y.3
  • 114
    • 0034208485 scopus 로고    scopus 로고
    • Clinical significance of distribution patterns of P53 immunoreactivity in astrocytic tumors
    • S.L. Hwang, Y.R. Hong, and A.S. Lieu Clinical significance of distribution patterns of P53 immunoreactivity in astrocytic tumors Kaohsiung J Med Sci 16 2000 279 284
    • (2000) Kaohsiung J Med Sci , vol.16 , pp. 279-284
    • Hwang, S.L.1    Hong, Y.R.2    Lieu, A.S.3
  • 115
    • 41149167213 scopus 로고    scopus 로고
    • 1p36 is a preferential target of chromosome 1 deletions in astrocytic tumours and homozygously deleted in a subset of glioblastomas
    • K. Ichimura, A.P. Vogazianou, and L. Liu 1p36 is a preferential target of chromosome 1 deletions in astrocytic tumours and homozygously deleted in a subset of glioblastomas Oncogene 27 2008 2097 2108
    • (2008) Oncogene , vol.27 , pp. 2097-2108
    • Ichimura, K.1    Vogazianou, A.P.2    Liu, L.3
  • 116
    • 61849166668 scopus 로고    scopus 로고
    • Epidermal growth factor receptor extracellular domain mutations in primary glioblastoma
    • A. Idbaih, J. Aimard, and B. Boisselier Epidermal growth factor receptor extracellular domain mutations in primary glioblastoma Neuropathol Appl Neurobiol 35 2009 208 213
    • (2009) Neuropathol Appl Neurobiol , vol.35 , pp. 208-213
    • Idbaih, A.1    Aimard, J.2    Boisselier, B.3
  • 117
    • 3142672781 scopus 로고    scopus 로고
    • Protocol of radiotherapy for glioblastoma according to the expression of HIF-1
    • N. Irie, T. Matsuo, and I. Nagata Protocol of radiotherapy for glioblastoma according to the expression of HIF-1 Brain Tumor Pathol 21 2004 1 6
    • (2004) Brain Tumor Pathol , vol.21 , pp. 1-6
    • Irie, N.1    Matsuo, T.2    Nagata, I.3
  • 118
    • 0742331383 scopus 로고    scopus 로고
    • Matrix metalloproteinase 2 (MMP-2) immunoreactive protein is associated with poor grade and survival in brain neoplasms
    • J. Jaalinoja, R. Herva, and M. Korpela Matrix metalloproteinase 2 (MMP-2) immunoreactive protein is associated with poor grade and survival in brain neoplasms J Neurooncol 46 2000 81 90
    • (2000) J Neurooncol , vol.46 , pp. 81-90
    • Jaalinoja, J.1    Herva, R.2    Korpela, M.3
  • 119
    • 18144444925 scopus 로고    scopus 로고
    • Tumor suppressor gene alterations in malignant gliomas: Histopathological associations and prognostic evaluation
    • C.D. James, E. Galanis, and L. Frederick Tumor suppressor gene alterations in malignant gliomas: histopathological associations and prognostic evaluation Int J Oncol 15 1999 547 553
    • (1999) Int J Oncol , vol.15 , pp. 547-553
    • James, C.D.1    Galanis, E.2    Frederick, L.3
  • 120
    • 33745761030 scopus 로고    scopus 로고
    • Amplification of the epidermal growth factor receptor in astrocytic tumours by chromogenic in situ hybridization: Association with clinicopathological features and patient survival
    • S. Jarvela, S. Jarvella, and H. Helin Amplification of the epidermal growth factor receptor in astrocytic tumours by chromogenic in situ hybridization: association with clinicopathological features and patient survival Neuropathol Appl Neurobiol 32 2006 441 450
    • (2006) Neuropathol Appl Neurobiol , vol.32 , pp. 441-450
    • Jarvela, S.1    Jarvella, S.2    Helin, H.3
  • 121
    • 77952261312 scopus 로고    scopus 로고
    • Specific expression profile and prognostic significance of peroxiredoxins in grade II-IV astrocytic brain tumors
    • S. Jarvela, I. Rantala, and A. Rodriguez Specific expression profile and prognostic significance of peroxiredoxins in grade II-IV astrocytic brain tumors BMC Cancer 10 2010 104
    • (2010) BMC Cancer , vol.10 , pp. 104
    • Jarvela, S.1    Rantala, I.2    Rodriguez, A.3
  • 122
    • 57549099418 scopus 로고    scopus 로고
    • High incidence of MGMT promoter methylation in primary glioblastomas without correlation with TP53 gene mutations
    • E. Jesien-Lewandowicz, D. Jesionek-Kupnicka, and I. Zawlik High incidence of MGMT promoter methylation in primary glioblastomas without correlation with TP53 gene mutations Cancer Genet Cytogenet 188 2009 77 82
    • (2009) Cancer Genet Cytogenet , vol.188 , pp. 77-82
    • Jesien-Lewandowicz, E.1    Jesionek-Kupnicka, D.2    Zawlik, I.3
  • 123
    • 34547182884 scopus 로고    scopus 로고
    • FABP7 expression in glioblastomas: Relation to prognosis, invasion and EGFR status
    • G. Kaloshi, K. Mokhtari, and C. Carpentier FABP7 expression in glioblastomas: relation to prognosis, invasion and EGFR status J Neurooncol 84 2007 245 248
    • (2007) J Neurooncol , vol.84 , pp. 245-248
    • Kaloshi, G.1    Mokhtari, K.2    Carpentier, C.3
  • 124
    • 1142310735 scopus 로고    scopus 로고
    • 6-methylguanine-deoxyribonucleic acid methyltransferase gene and prognosis in patients with high-grade astrocytic tumors treated with surgery, radiotherapy, and 1-(4-amino-2-methyl-5-pyrimidinyl)methyl-3-(2-chloroethyl)-3-nitrosourea-based chemotherapy
    • [discussion 357]
    • 6-methylguanine-deoxyribonucleic acid methyltransferase gene and prognosis in patients with high-grade astrocytic tumors treated with surgery, radiotherapy, and 1-(4-amino-2-methyl-5-pyrimidinyl)methyl-3-(2-chloroethyl)-3-nitrosourea-based chemotherapy Neurosurgery 54 2004 349 357 [discussion 357]
    • (2004) Neurosurgery , vol.54 , pp. 349-357
    • Kamiryo, T.1    Tada, K.2    Shiraishi, S.3
  • 125
    • 0036239616 scopus 로고    scopus 로고
    • Analysis of homozygous deletion of the p16 gene and correlation with survival in patients with glioblastoma multiforme
    • T. Kamiryo, K. Tada, and S. Shiraishi Analysis of homozygous deletion of the p16 gene and correlation with survival in patients with glioblastoma multiforme J Neurosurg 96 2002 815 822
    • (2002) J Neurosurg , vol.96 , pp. 815-822
    • Kamiryo, T.1    Tada, K.2    Shiraishi, S.3
  • 127
    • 75049083501 scopus 로고    scopus 로고
    • Stem cell associated gene expression in glioblastoma multiforme: Relationship to survival and the subventricular zone
    • M. Kappadakunnel, A. Eskin, and J. Dong Stem cell associated gene expression in glioblastoma multiforme: relationship to survival and the subventricular zone J Neurooncol 96 2009 359 367
    • (2009) J Neurooncol , vol.96 , pp. 359-367
    • Kappadakunnel, M.1    Eskin, A.2    Dong, J.3
  • 128
    • 33645694302 scopus 로고    scopus 로고
    • Different angiogenic phenotypes in primary and secondary glioblastomas
    • S. Karcher, H.-H. Steiner, and R. Ahmadi Different angiogenic phenotypes in primary and secondary glioblastomas Int J Cancer 118 2006 2182 2189
    • (2006) Int J Cancer , vol.118 , pp. 2182-2189
    • Karcher, S.1    Steiner, H.-H.2    Ahmadi, R.3
  • 129
    • 0345169950 scopus 로고    scopus 로고
    • PTEN gene mutation and high MIB-1 labeling index may contribute to dissemination in patients with glioblastoma
    • H. Kato, M. Fujimura, and T. Kumabe PTEN gene mutation and high MIB-1 labeling index may contribute to dissemination in patients with glioblastoma J Clin Neurosci 11 2004 37 41
    • (2004) J Clin Neurosci , vol.11 , pp. 37-41
    • Kato, H.1    Fujimura, M.2    Kumabe, T.3
  • 130
    • 58149168580 scopus 로고    scopus 로고
    • The role of a single nucleotide polymorphism of MDM2 in glioblastoma multiforme
    • R.G. Khatri, K. Navaratne, and R.J. Weil The role of a single nucleotide polymorphism of MDM2 in glioblastoma multiforme J Neurosurg 109 2008 842 848
    • (2008) J Neurosurg , vol.109 , pp. 842-848
    • Khatri, R.G.1    Navaratne, K.2    Weil, R.J.3
  • 131
    • 76649130555 scopus 로고    scopus 로고
    • Integrative genome analysis reveals an oncomir/oncogene cluster regulating glioblastoma survivorship
    • H. Kim, W. Huang, and X. Jiang Integrative genome analysis reveals an oncomir/oncogene cluster regulating glioblastoma survivorship Proc Natl Acad Sci U S A 107 2010 2183 2188
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 2183-2188
    • Kim, H.1    Huang, W.2    Jiang, X.3
  • 132
    • 0031973661 scopus 로고    scopus 로고
    • Image cytometric measurement of nuclear proliferation markers (MIB-1, PCNA) in astrocytomas Prognostic significance
    • L.J. Kirkegaard, P.B. DeRose, and B. Yao Image cytometric measurement of nuclear proliferation markers (MIB-1, PCNA) in astrocytomas Prognostic significance Am J Clin Pathol 109 1998 69 74
    • (1998) Am J Clin Pathol , vol.109 , pp. 69-74
    • Kirkegaard, L.J.1    Derose, P.B.2    Yao, B.3
  • 135
    • 34447115084 scopus 로고    scopus 로고
    • Prognostic significance of the immunohistochemical staining of cleaved caspase-3, an activated form of caspase-3, in gliomas
    • T. Kobayashi, J. Masumoto, and T. Tada Prognostic significance of the immunohistochemical staining of cleaved caspase-3, an activated form of caspase-3, in gliomas Clin Cancer Res 13 2007 3868 3874
    • (2007) Clin Cancer Res , vol.13 , pp. 3868-3874
    • Kobayashi, T.1    Masumoto, J.2    Tada, T.3
  • 136
    • 53349166957 scopus 로고    scopus 로고
    • Prognosis of glioma patients by combined immunostaining for survivin, Ki-67 and epidermal growth factor receptor
    • M. Kogiku, I. Ohsawa, and K. Matsumoto Prognosis of glioma patients by combined immunostaining for survivin, Ki-67 and epidermal growth factor receptor J Clin Neurosci 15 2008 1198 1203
    • (2008) J Clin Neurosci , vol.15 , pp. 1198-1203
    • Kogiku, M.1    Ohsawa, I.2    Matsumoto, K.3
  • 137
    • 58949099258 scopus 로고    scopus 로고
    • Prognostic significance of c-Met expression in glioblastomas
    • D.S. Kong, S.Y. Song, and D.H. Kim Prognostic significance of c-Met expression in glioblastomas Cancer 115 2009 140 148
    • (2009) Cancer , vol.115 , pp. 140-148
    • Kong, D.S.1    Song, S.Y.2    Kim, D.H.3
  • 138
    • 47549114245 scopus 로고    scopus 로고
    • Expression of nuclear factor-kappaB in human astrocytomas: Relation to pI kappa Ba, vascular endothelial growth factor, Cox-2, microvascular characteristics, and survival
    • P. Korkolopoulou, G. Levidou, and A.A. Saetta Expression of nuclear factor-kappaB in human astrocytomas: relation to pI kappa Ba, vascular endothelial growth factor, Cox-2, microvascular characteristics, and survival Hum Pathol 39 2008 1143 1152
    • (2008) Hum Pathol , vol.39 , pp. 1143-1152
    • Korkolopoulou, P.1    Levidou, G.2    Saetta, A.A.3
  • 139
    • 0034850421 scopus 로고    scopus 로고
    • Mitosin and DNA topoisomerase IIalpha: Two novel proliferation markers in the prognostication of diffuse astrocytoma patient survival
    • P. Korkolopoulou, E. Patsouris, and A.E. Konstantinidou Mitosin and DNA topoisomerase IIalpha: two novel proliferation markers in the prognostication of diffuse astrocytoma patient survival Appl Immunohistochem Mol Morphol 9 2001 207 214
    • (2001) Appl Immunohistochem Mol Morphol , vol.9 , pp. 207-214
    • Korkolopoulou, P.1    Patsouris, E.2    Konstantinidou, A.E.3
  • 140
    • 2942707871 scopus 로고    scopus 로고
    • Hypoxia-inducible factor 1alpha/vascular endothelial growth factor axis in astrocytomas. Associations with microvessel morphometry, proliferation and prognosis
    • P. Korkolopoulou, E. Patsouris, and A.E. Konstantinidou Hypoxia-inducible factor 1alpha/vascular endothelial growth factor axis in astrocytomas. Associations with microvessel morphometry, proliferation and prognosis Neuropathol Appl Neurobiol 30 2004 267 278
    • (2004) Neuropathol Appl Neurobiol , vol.30 , pp. 267-278
    • Korkolopoulou, P.1    Patsouris, E.2    Konstantinidou, A.E.3
  • 141
    • 33947108844 scopus 로고    scopus 로고
    • Expression of hypoxia-related tissue factors in astrocytic gliomas. A multivariate survival study with emphasis upon carbonic anhydrase IX
    • P. Korkolopoulou, M. Perdiki, and I. Thymara Expression of hypoxia-related tissue factors in astrocytic gliomas. A multivariate survival study with emphasis upon carbonic anhydrase IX Hum Pathol 38 2007 629 638
    • (2007) Hum Pathol , vol.38 , pp. 629-638
    • Korkolopoulou, P.1    Perdiki, M.2    Thymara, I.3
  • 142
    • 0036020497 scopus 로고    scopus 로고
    • Immunohistochemical markers for prognosis of cerebral glioblastomas
    • A. Korshunov, A. Golanov, and R. Sycheva Immunohistochemical markers for prognosis of cerebral glioblastomas J Neurooncol 58 2002 217 236
    • (2002) J Neurooncol , vol.58 , pp. 217-236
    • Korshunov, A.1    Golanov, A.2    Sycheva, R.3
  • 143
    • 0032794642 scopus 로고    scopus 로고
    • Prognostic value of tumour associated antigen immunoreactivity and apoptosis in cerebral glioblastomas: An analysis of 168 cases
    • A. Korshunov, A. Golanov, and R. Sycheva Prognostic value of tumour associated antigen immunoreactivity and apoptosis in cerebral glioblastomas: an analysis of 168 cases J Clin Pathol 52 1999 574 580
    • (1999) J Clin Pathol , vol.52 , pp. 574-580
    • Korshunov, A.1    Golanov, A.2    Sycheva, R.3
  • 144
    • 23444435222 scopus 로고    scopus 로고
    • The prognostic relevance of molecular alterations in glioblastomas for patients age < 50 years
    • A. Korshunov, R. Sycheva, and A. Golanov The prognostic relevance of molecular alterations in glioblastomas for patients age < 50 years Cancer 104 2005 825 832
    • (2005) Cancer , vol.104 , pp. 825-832
    • Korshunov, A.1    Sycheva, R.2    Golanov, A.3
  • 145
    • 33646230037 scopus 로고    scopus 로고
    • Genetically distinct and clinically relevant subtypes of glioblastoma defined by array-based comparative genomic hybridization (array-CGH)
    • A. Korshunov, R. Sycheva, and A. Golanov Genetically distinct and clinically relevant subtypes of glioblastoma defined by array-based comparative genomic hybridization (array-CGH) Acta Neuropathol 111 2006 465 474
    • (2006) Acta Neuropathol , vol.111 , pp. 465-474
    • Korshunov, A.1    Sycheva, R.2    Golanov, A.3
  • 146
    • 0033772866 scopus 로고    scopus 로고
    • Molecular analysis of the PTEN, TP53 and CDKN2A tumor suppressor genes in long-term survivors of glioblastoma multiforme
    • J.A. Kraus, N. Glesmann, and M. Beck Molecular analysis of the PTEN, TP53 and CDKN2A tumor suppressor genes in long-term survivors of glioblastoma multiforme J Neurooncol 48 2000 89 94
    • (2000) J Neurooncol , vol.48 , pp. 89-94
    • Kraus, J.A.1    Glesmann, N.2    Beck, M.3
  • 147
    • 0035038225 scopus 로고    scopus 로고
    • Molecular genetic alterations in glioblastomas with oligodendroglial component
    • J.A. Kraus, K. Lamszus, and N. Glesmann Molecular genetic alterations in glioblastomas with oligodendroglial component Acta Neuropathol 101 2001 311 320
    • (2001) Acta Neuropathol , vol.101 , pp. 311-320
    • Kraus, J.A.1    Lamszus, K.2    Glesmann, N.3
  • 148
    • 17944385411 scopus 로고    scopus 로고
    • TP53 gene mutations, nuclear p53 accumulation, expression of Waf/p21, Bcl-2, and CD95 (APO-1/Fas) proteins are not prognostic factors in de novo glioblastoma multiforme
    • J.A. Kraus, M. Wenghoefer, and N. Glesmann TP53 gene mutations, nuclear p53 accumulation, expression of Waf/p21, Bcl-2, and CD95 (APO-1/Fas) proteins are not prognostic factors in de novo glioblastoma multiforme J Neurooncol 52 2001 263 272
    • (2001) J Neurooncol , vol.52 , pp. 263-272
    • Kraus, J.A.1    Wenghoefer, M.2    Glesmann, N.3
  • 149
    • 33646230317 scopus 로고    scopus 로고
    • Glycoprotein nonmetastatic melanoma protein B, a potential molecular therapeutic target in patients with glioblastoma multiforme
    • C.T. Kuan, K. Wakiya, and J.M. Dowell Glycoprotein nonmetastatic melanoma protein B, a potential molecular therapeutic target in patients with glioblastoma multiforme Clin Cancer Res 12 2006 1970 1982
    • (2006) Clin Cancer Res , vol.12 , pp. 1970-1982
    • Kuan, C.T.1    Wakiya, K.2    Dowell, J.M.3
  • 150
    • 33748132555 scopus 로고    scopus 로고
    • TRAIL-receptor expression is an independent prognostic factor for survival in patients with a primary glioblastoma multiforme
    • J.M.A. Kuijlen, J.J.A. Mooij, and I. Platteel TRAIL-receptor expression is an independent prognostic factor for survival in patients with a primary glioblastoma multiforme J Neurooncol 78 2006 161 171
    • (2006) J Neurooncol , vol.78 , pp. 161-171
    • Kuijlen, J.M.A.1    Mooij, J.J.A.2    Platteel, I.3
  • 151
    • 18644367170 scopus 로고    scopus 로고
    • Prognostic significance of an apoptotic index and apoptosis/proliferation ratio for patients with high-grade astrocytomas
    • H. Kuriyama, K.R. Lamborn, and J.R. O'Fallon Prognostic significance of an apoptotic index and apoptosis/proliferation ratio for patients with high-grade astrocytomas Neuro Oncol 4 2002 179 186
    • (2002) Neuro Oncol , vol.4 , pp. 179-186
    • Kuriyama, H.1    Lamborn, K.R.2    O'Fallon, J.R.3
  • 152
    • 0035280251 scopus 로고    scopus 로고
    • Quantitative real-time PCR does not show selective targeting of p14(ARF) but concomitant inactivation of both p16(INK4A) and p14(ARF) in 105 human primary gliomas
    • M. Labuhn, G. Jones, and E.J. Speel Quantitative real-time PCR does not show selective targeting of p14(ARF) but concomitant inactivation of both p16(INK4A) and p14(ARF) in 105 human primary gliomas Oncogene 20 2001 1103 1109
    • (2001) Oncogene , vol.20 , pp. 1103-1109
    • Labuhn, M.1    Jones, G.2    Speel, E.J.3
  • 153
    • 77953351926 scopus 로고    scopus 로고
    • All the 1p19q codeleted gliomas are mutated on IDH1 or IDH2
    • M. Labussiere, A. Idbaih, and X.W. Wang All the 1p19q codeleted gliomas are mutated on IDH1 or IDH2 Neurology 74 2010 1886 1890
    • (2010) Neurology , vol.74 , pp. 1886-1890
    • Labussiere, M.1    Idbaih, A.2    Wang, X.W.3
  • 154
    • 65749087298 scopus 로고    scopus 로고
    • Neurosphere formation is an independent predictor of clinical outcome in malignant glioma
    • D.R. Laks, M. Masterman-Smith, and K. Visnyei Neurosphere formation is an independent predictor of clinical outcome in malignant glioma Stem Cells 27 2009 980 987
    • (2009) Stem Cells , vol.27 , pp. 980-987
    • Laks, D.R.1    Masterman-Smith, M.2    Visnyei, K.3
  • 155
    • 34547486908 scopus 로고    scopus 로고
    • Increase in PGE2 biosynthesis induces a Bax dependent apoptosis correlated to patients' survival in glioblastoma multiforme
    • L. Lalier, P.F. Cartron, and F. Pedelaborde Increase in PGE2 biosynthesis induces a Bax dependent apoptosis correlated to patients' survival in glioblastoma multiforme Oncogene 26 2007 4999 5009
    • (2007) Oncogene , vol.26 , pp. 4999-5009
    • Lalier, L.1    Cartron, P.F.2    Pedelaborde, F.3
  • 156
    • 34447251515 scopus 로고    scopus 로고
    • Activated ERK1/2 expression in glioblastoma multiforme and in peritumor tissue
    • G. Lama, A. Mangiola, and C. Anile Activated ERK1/2 expression in glioblastoma multiforme and in peritumor tissue Int J Oncol 30 2007 1333 1342
    • (2007) Int J Oncol , vol.30 , pp. 1333-1342
    • Lama, G.1    Mangiola, A.2    Anile, C.3
  • 157
    • 0033557597 scopus 로고    scopus 로고
    • Final report on the University of California-San Francisco experience with bromodeoxyuridine labeling index as a prognostic factor for the survival of glioma patients
    • K.R. Lamborn, M.D. Prados, and S.B. Kaplan Final report on the University of California-San Francisco experience with bromodeoxyuridine labeling index as a prognostic factor for the survival of glioma patients Cancer 85 1999 925 935
    • (1999) Cancer , vol.85 , pp. 925-935
    • Lamborn, K.R.1    Prados, M.D.2    Kaplan, S.B.3
  • 158
    • 33645164077 scopus 로고    scopus 로고
    • Epidermal growth factor receptor gene amplification and protein expression in glioblastoma multiforme: Prognostic significance and relationship to other prognostic factors
    • L.J. Layfield, C. Willmore, and S. Tripp Epidermal growth factor receptor gene amplification and protein expression in glioblastoma multiforme: prognostic significance and relationship to other prognostic factors Appl Immunohistochem Mol Morphol 14 2006 91 96
    • (2006) Appl Immunohistochem Mol Morphol , vol.14 , pp. 91-96
    • Layfield, L.J.1    Willmore, C.2    Tripp, S.3
  • 159
    • 0344412950 scopus 로고    scopus 로고
    • Expression of tenascin-C in various human brain tumors and its relevance for survival in patients with astrocytoma
    • A. Leins, P. Riva, and R. Lindstedt Expression of tenascin-C in various human brain tumors and its relevance for survival in patients with astrocytoma Cancer 98 2003 2430 2439
    • (2003) Cancer , vol.98 , pp. 2430-2439
    • Leins, A.1    Riva, P.2    Lindstedt, R.3
  • 160
    • 62449321780 scopus 로고    scopus 로고
    • Unsupervised analysis of transcriptomic profiles reveals six glioma subtypes
    • A. Li, J. Walling, and S. Ahn Unsupervised analysis of transcriptomic profiles reveals six glioma subtypes Cancer Res 69 2009 2091 2099
    • (2009) Cancer Res , vol.69 , pp. 2091-2099
    • Li, A.1    Walling, J.2    Ahn, S.3
  • 161
    • 47749117161 scopus 로고    scopus 로고
    • Impact of p53 status to response of temozolomide in low MGMT expression glioblastomas: Preliminary results
    • S. Li, T. Jiang, and G. Li Impact of p53 status to response of temozolomide in low MGMT expression glioblastomas: preliminary results Neurol Res 30 2008 567 570
    • (2008) Neurol Res , vol.30 , pp. 567-570
    • Li, S.1    Jiang, T.2    Li, G.3
  • 162
    • 68249139757 scopus 로고    scopus 로고
    • Prognostic factors influencing clinical outcomes of glioblastoma multiforme
    • S.W. Li, X.G. Qiu, and B.S. Chen Prognostic factors influencing clinical outcomes of glioblastoma multiforme Chin Med J (Engl) 122 2009 1245 1249
    • (2009) Chin Med J (Engl) , vol.122 , pp. 1245-1249
    • Li, S.W.1    Qiu, X.G.2    Chen, B.S.3
  • 163
    • 33745071151 scopus 로고    scopus 로고
    • Nuclear FABP7 immunoreactivity is preferentially expressed in infiltrative glioma and is associated with poor prognosis in EGFR-overexpressing glioblastoma
    • Y. Liang, A.W. Bollen, and K.D. Aldape Nuclear FABP7 immunoreactivity is preferentially expressed in infiltrative glioma and is associated with poor prognosis in EGFR-overexpressing glioblastoma BMC Cancer 6 2006 97
    • (2006) BMC Cancer , vol.6 , pp. 97
    • Liang, Y.1    Bollen, A.W.2    Aldape, K.D.3
  • 164
    • 20244387732 scopus 로고    scopus 로고
    • Gene expression profiling reveals molecularly and clinically distinct subtypes of glioblastoma multiforme
    • Y. Liang, M. Diehn, and N. Watson Gene expression profiling reveals molecularly and clinically distinct subtypes of glioblastoma multiforme Proc Natl Acad Sci U S A 102 2005 5814 5819
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 5814-5819
    • Liang, Y.1    Diehn, M.2    Watson, N.3
  • 165
    • 0031752950 scopus 로고    scopus 로고
    • Allelic deletion analyses of MMAC/PTEN and DMBT1 loci in gliomas: Relationship to prognostic significance
    • H. Lin, M.L. Bondy, and L.A. Langford Allelic deletion analyses of MMAC/PTEN and DMBT1 loci in gliomas: relationship to prognostic significance Clin Cancer Res 4 1998 2447 2454
    • (1998) Clin Cancer Res , vol.4 , pp. 2447-2454
    • Lin, H.1    Bondy, M.L.2    Langford, L.A.3
  • 166
    • 54049096415 scopus 로고    scopus 로고
    • The methylenetetrahydrofolate reductase (MTHFR) variant c.677C>T (A222V) influences overall survival of patients with glioblastoma multiforme
    • M. Linnebank, A. Semmler, and S. Moskau The methylenetetrahydrofolate reductase (MTHFR) variant c.677C>T (A222V) influences overall survival of patients with glioblastoma multiforme Neuro Oncol 10 2008 548 552
    • (2008) Neuro Oncol , vol.10 , pp. 548-552
    • Linnebank, M.1    Semmler, A.2    Moskau, S.3
  • 167
    • 70349926138 scopus 로고    scopus 로고
    • Expression pattern and clinical prognostic relevance of bone morphogenetic protein-2 in human gliomas
    • C. Liu, G. Tian, and Y. Tu Expression pattern and clinical prognostic relevance of bone morphogenetic protein-2 in human gliomas Jpn J Clin Oncol 39 2009 625 631
    • (2009) Jpn J Clin Oncol , vol.39 , pp. 625-631
    • Liu, C.1    Tian, G.2    Tu, Y.3
  • 168
    • 33845332412 scopus 로고    scopus 로고
    • A genome-wide screen reveals functional gene clusters in the cancer genome and identifies EphA2 as a mitogen in glioblastoma
    • F. Liu, P.J. Park, and W. Lai A genome-wide screen reveals functional gene clusters in the cancer genome and identifies EphA2 as a mitogen in glioblastoma Cancer Res 66 2006 10815 10823
    • (2006) Cancer Res , vol.66 , pp. 10815-10823
    • Liu, F.1    Park, P.J.2    Lai, W.3
  • 169
    • 27744503993 scopus 로고    scopus 로고
    • Clinical significance of EGFR amplification and the aberrant EGFRvIII transcript in conventionally treated astrocytic gliomas
    • L. Liu, L.M. Backlund, and B.R. Nilsson Clinical significance of EGFR amplification and the aberrant EGFRvIII transcript in conventionally treated astrocytic gliomas J Mol Med 83 2005 917 926
    • (2005) J Mol Med , vol.83 , pp. 917-926
    • Liu, L.1    Backlund, L.M.2    Nilsson, B.R.3
  • 170
    • 33645734725 scopus 로고    scopus 로고
    • FoxM1B is overexpressed in human glioblastomas and critically regulates the tumorigenicity of glioma cells
    • M. Liu, B. Dai, and S.H. Kang FoxM1B is overexpressed in human glioblastomas and critically regulates the tumorigenicity of glioma cells Cancer Res 66 2006 3593 3602
    • (2006) Cancer Res , vol.66 , pp. 3593-3602
    • Liu, M.1    Dai, B.2    Kang, S.H.3
  • 171
    • 68849114479 scopus 로고    scopus 로고
    • Expression and functional roles of Smad1 and BMPR-IB in glioma development
    • S. Liu, Z. Tian, and F. Yin Expression and functional roles of Smad1 and BMPR-IB in glioma development Cancer Invest 27 2009 734 740
    • (2009) Cancer Invest , vol.27 , pp. 734-740
    • Liu, S.1    Tian, Z.2    Yin, F.3
  • 172
    • 77952525364 scopus 로고    scopus 로고
    • Polymorphisms of LIG4, BTBD2, HMGA2, and RTEL1 genes involved in the double-strand break repair pathway predict glioblastoma survival
    • Y. Liu, S. Shete, and C.J. Etzel Polymorphisms of LIG4, BTBD2, HMGA2, and RTEL1 genes involved in the double-strand break repair pathway predict glioblastoma survival J Clin Oncol 28 2010 2467 2474
    • (2010) J Clin Oncol , vol.28 , pp. 2467-2474
    • Liu, Y.1    Shete, S.2    Etzel, C.J.3
  • 173
    • 3242777006 scopus 로고    scopus 로고
    • Association between laminin-8 and glial tumor grade, recurrence, and patient survival
    • J.Y. Ljubimova, M. Fugita, and N.M. Khazenzon Association between laminin-8 and glial tumor grade, recurrence, and patient survival Cancer 101 2004 604 612
    • (2004) Cancer , vol.101 , pp. 604-612
    • Ljubimova, J.Y.1    Fugita, M.2    Khazenzon, N.M.3
  • 174
    • 24644461021 scopus 로고    scopus 로고
    • Association of chromosome 7, chromosome 10 and EGFR gene amplification in glioblastoma multiforme
    • C. Lopez-Gines, M. Cerda-Nicolas, and R. Gil-Benso Association of chromosome 7, chromosome 10 and EGFR gene amplification in glioblastoma multiforme Clin Neuropathol 24 2005 209 218
    • (2005) Clin Neuropathol , vol.24 , pp. 209-218
    • Lopez-Gines, C.1    Cerda-Nicolas, M.2    Gil-Benso, R.3
  • 175
    • 64049105722 scopus 로고    scopus 로고
    • Down-regulation of K-ras and H-ras in human brain gliomas
    • R. Lymbouridou, G. Soufla, and A.M. Chatzinikola Down-regulation of K-ras and H-ras in human brain gliomas Eur J Cancer 45 2009 1294 1303
    • (2009) Eur J Cancer , vol.45 , pp. 1294-1303
    • Lymbouridou, R.1    Soufla, G.2    Chatzinikola, A.M.3
  • 176
    • 37249074829 scopus 로고    scopus 로고
    • Stem cell marker nestin and c-Jun NH2-terminal kinases in tumor and peritumor areas of glioblastoma multiforme: Possible prognostic implications
    • A. Mangiola, G. Lama, and C. Giannitelli Stem cell marker nestin and c-Jun NH2-terminal kinases in tumor and peritumor areas of glioblastoma multiforme: possible prognostic implications Clin Cancer Res 13 2007 6970 6977
    • (2007) Clin Cancer Res , vol.13 , pp. 6970-6977
    • Mangiola, A.1    Lama, G.2    Giannitelli, C.3
  • 177
    • 69949087520 scopus 로고    scopus 로고
    • A microarray-based DNA methylation study of glioblastoma multiforme
    • R. Martinez, J.I. Martin-Subero, and V. Rohde A microarray-based DNA methylation study of glioblastoma multiforme Epigenetics 4 2009 255 264
    • (2009) Epigenetics , vol.4 , pp. 255-264
    • Martinez, R.1    Martin-Subero, J.I.2    Rohde, V.3
  • 178
    • 75049083689 scopus 로고    scopus 로고
    • Different molecular patterns in glioblastoma multiforme subtypes upon recurrence
    • R. Martinez, V. Rohde, and G. Schackert Different molecular patterns in glioblastoma multiforme subtypes upon recurrence J Neurooncol 96 2009 321 329
    • (2009) J Neurooncol , vol.96 , pp. 321-329
    • Martinez, R.1    Rohde, V.2    Schackert, G.3
  • 179
    • 33947280464 scopus 로고    scopus 로고
    • Hypermethylation of the proapoptotic gene TMS1/ASC: Prognostic importance in glioblastoma multiforme
    • R. Martinez, G. Schackert, and M. Esteller Hypermethylation of the proapoptotic gene TMS1/ASC: prognostic importance in glioblastoma multiforme J Neurooncol 82 2007 133 139
    • (2007) J Neurooncol , vol.82 , pp. 133-139
    • Martinez, R.1    Schackert, G.2    Esteller, M.3
  • 180
    • 57349117925 scopus 로고    scopus 로고
    • Prognostic relevance of SOCS3 hypermethylation in patients with glioblastoma multiforme
    • M. Martini, R. Pallini, and G. Luongo Prognostic relevance of SOCS3 hypermethylation in patients with glioblastoma multiforme Int J Cancer 123 2008 2955 2960
    • (2008) Int J Cancer , vol.123 , pp. 2955-2960
    • Martini, M.1    Pallini, R.2    Luongo, G.3
  • 181
    • 58549101882 scopus 로고    scopus 로고
    • Osteopontin expression correlates with angiogenesis and survival in malignant astrocytoma
    • K. Matusan-Ilijas, S. Behrem, and N. Jonjic Osteopontin expression correlates with angiogenesis and survival in malignant astrocytoma Pathol Oncol Res 14 2008 293 298
    • (2008) Pathol Oncol Res , vol.14 , pp. 293-298
    • Matusan-Ilijas, K.1    Behrem, S.2    Jonjic, N.3
  • 182
    • 67649413407 scopus 로고    scopus 로고
    • Endocan expression and localization in human glioblastomas
    • C.A. Maurage, E. Adam, and J.F. Mineo Endocan expression and localization in human glioblastomas J Neuropathol Exp Neurol 68 2009 633 641
    • (2009) J Neuropathol Exp Neurol , vol.68 , pp. 633-641
    • Maurage, C.A.1    Adam, E.2    Mineo, J.F.3
  • 183
    • 0346425237 scopus 로고    scopus 로고
    • Prognostic relevance of MAPK expression in glioblastoma multiforme
    • C. Mawrin, S. Diete, and T. Treuheit Prognostic relevance of MAPK expression in glioblastoma multiforme Int J Oncol 23 2003 641 648
    • (2003) Int J Oncol , vol.23 , pp. 641-648
    • Mawrin, C.1    Diete, S.2    Treuheit, T.3
  • 184
    • 34247866468 scopus 로고    scopus 로고
    • IQGAP1 and IGFBP2: Valuable biomarkers for determining prognosis in glioma patients
    • K.L. McDonald, M.G. O'Sullivan, and J.F. Parkinson IQGAP1 and IGFBP2: valuable biomarkers for determining prognosis in glioma patients J Neuropathol Exp Neurol 66 2007 405 417
    • (2007) J Neuropathol Exp Neurol , vol.66 , pp. 405-417
    • McDonald, K.L.1    O'Sullivan, M.G.2    Parkinson, J.F.3
  • 185
    • 0035826785 scopus 로고    scopus 로고
    • Proliferation index is related to patient age in glioblastoma
    • P.E. McKeever, L. Junck, and M.S. Strawderman Proliferation index is related to patient age in glioblastoma Neurology 56 2001 1216 1218
    • (2001) Neurology , vol.56 , pp. 1216-1218
    • McKeever, P.E.1    Junck, L.2    Strawderman, M.S.3
  • 186
    • 69549111318 scopus 로고    scopus 로고
    • MGMT promoter hypermethylation in a series of 104 glioblastomas
    • M. Mellai, V. Caldera, and L. Annovazzi MGMT promoter hypermethylation in a series of 104 glioblastomas Cancer Genomics Proteomics 6 2009 219 227
    • (2009) Cancer Genomics Proteomics , vol.6 , pp. 219-227
    • Mellai, M.1    Caldera, V.2    Annovazzi, L.3
  • 187
    • 42349106146 scopus 로고    scopus 로고
    • Expression of TLR9 within human glioblastoma
    • Y. Meng, M. Kujas, and Y. Marie Expression of TLR9 within human glioblastoma J Neurooncol 88 2008 19 25
    • (2008) J Neurooncol , vol.88 , pp. 19-25
    • Meng, Y.1    Kujas, M.2    Marie, Y.3
  • 188
    • 70350109380 scopus 로고    scopus 로고
    • Prognostic impact of O6-methylguanine-DNA methyltransferase silencing in patients with recurrent glioblastoma multiforme who undergo surgery and carmustine wafer implantation: A prospective patient cohort
    • P. Metellus, B. Coulibaly, and I. Nanni Prognostic impact of O6-methylguanine-DNA methyltransferase silencing in patients with recurrent glioblastoma multiforme who undergo surgery and carmustine wafer implantation: a prospective patient cohort Cancer 115 2009 4783 4794
    • (2009) Cancer , vol.115 , pp. 4783-4794
    • Metellus, P.1    Coulibaly, B.2    Nanni, I.3
  • 189
    • 36349000329 scopus 로고    scopus 로고
    • Low HER2-expressing glioblastomas are more often secondary to anaplastic transformation of low-grade glioma
    • J.F. Mineo, A. Bordron, and M. Baroncini Low HER2-expressing glioblastomas are more often secondary to anaplastic transformation of low-grade glioma J Neurooncol 85 2007 281 287
    • (2007) J Neurooncol , vol.85 , pp. 281-287
    • Mineo, J.F.1    Bordron, A.2    Baroncini, M.3
  • 190
    • 34247843062 scopus 로고    scopus 로고
    • De novo erythropoietin receptor (EPO-R) expression in human neoplastic glial cells decreases with grade of malignancy but is favourably associated with patient survival
    • M. Mittelbronn, D. Capper, and B. Bunz De novo erythropoietin receptor (EPO-R) expression in human neoplastic glial cells decreases with grade of malignancy but is favourably associated with patient survival Neuropathol Appl Neurobiol 33 2007 299 307
    • (2007) Neuropathol Appl Neurobiol , vol.33 , pp. 299-307
    • Mittelbronn, M.1    Capper, D.2    Bunz, B.3
  • 191
    • 77649242821 scopus 로고    scopus 로고
    • Prognostic significance of nuclear DJ-1 expression in astrocytoma
    • Y. Miyajima, Y. Sato, and H. Oka Prognostic significance of nuclear DJ-1 expression in astrocytoma Anticancer Res 30 2010 265 269
    • (2010) Anticancer Res , vol.30 , pp. 265-269
    • Miyajima, Y.1    Sato, Y.2    Oka, H.3
  • 192
    • 23944439689 scopus 로고    scopus 로고
    • Instability of mitochondrial DNA and MRI and clinical correlations in malignant gliomas
    • L. Montanini, C. Regna-Gladin, and M. Eoli Instability of mitochondrial DNA and MRI and clinical correlations in malignant gliomas J Neurooncol 74 2005 87 89
    • (2005) J Neurooncol , vol.74 , pp. 87-89
    • Montanini, L.1    Regna-Gladin, C.2    Eoli, M.3
  • 193
    • 31144449690 scopus 로고    scopus 로고
    • Role of MIB1 in predicting survival in patients with glioblastomas
    • S.I. Moskowitz, T. Jin, and R.A. Prayson Role of MIB1 in predicting survival in patients with glioblastomas J Neurooncol 76 2006 193 200
    • (2006) J Neurooncol , vol.76 , pp. 193-200
    • Moskowitz, S.I.1    Jin, T.2    Prayson, R.A.3
  • 194
    • 46449115281 scopus 로고    scopus 로고
    • Stem cell-related "self-renewal" signature and high epidermal growth factor receptor expression associated with resistance to concomitant chemoradiotherapy in glioblastoma
    • A. Murat, E. Migliavacca, and T. Gorlia Stem cell-related "self-renewal" signature and high epidermal growth factor receptor expression associated with resistance to concomitant chemoradiotherapy in glioblastoma J Clin Oncol 26 2008 3015 3024
    • (2008) J Clin Oncol , vol.26 , pp. 3015-3024
    • Murat, A.1    Migliavacca, E.2    Gorlia, T.3
  • 195
    • 38749146312 scopus 로고    scopus 로고
    • Prognostic significance of O6-methylguanine-DNA methyltransferase protein expression in patients with recurrent glioblastoma treated with temozolomide
    • M. Nagane, K. Kobayashi, and A. Ohnishi Prognostic significance of O6-methylguanine-DNA methyltransferase protein expression in patients with recurrent glioblastoma treated with temozolomide Jpn J Clin Oncol 37 2007 897 906
    • (2007) Jpn J Clin Oncol , vol.37 , pp. 897-906
    • Nagane, M.1    Kobayashi, K.2    Ohnishi, A.3
  • 196
    • 67651246847 scopus 로고    scopus 로고
    • Prognostic significance of the immunohistochemical expression of O6-methylguanine-DNA methyltransferase, P-glycoprotein, and multidrug resistance protein-1 in glioblastomas
    • T. Nakagawa, K. Ido, and T. Sakuma Prognostic significance of the immunohistochemical expression of O6-methylguanine-DNA methyltransferase, P-glycoprotein, and multidrug resistance protein-1 in glioblastomas Neuropathology 29 2009 379 388
    • (2009) Neuropathology , vol.29 , pp. 379-388
    • Nakagawa, T.1    Ido, K.2    Sakuma, T.3
  • 197
    • 13444269098 scopus 로고    scopus 로고
    • Frequent LOH on 22q12.3 and TIMP-3 inactivation occur in the progression to secondary glioblastomas
    • M. Nakamura, E. Ishida, and K. Shimada Frequent LOH on 22q12.3 and TIMP-3 inactivation occur in the progression to secondary glioblastomas Lab Invest 85 2005 165 175
    • (2005) Lab Invest , vol.85 , pp. 165-175
    • Nakamura, M.1    Ishida, E.2    Shimada, K.3
  • 198
    • 0032248442 scopus 로고    scopus 로고
    • Frequent alterations of cell-cycle regulators in astrocytic tumors as detected by molecular genetic and immunohistochemical analyses
    • M. Nakamura, N. Konishi, and Y. Hiasa Frequent alterations of cell-cycle regulators in astrocytic tumors as detected by molecular genetic and immunohistochemical analyses Brain Tumor Pathol 15 1998 83 88
    • (1998) Brain Tumor Pathol , vol.15 , pp. 83-88
    • Nakamura, M.1    Konishi, N.2    Hiasa, Y.3
  • 199
    • 38049090322 scopus 로고    scopus 로고
    • Maternal embryonic leucine zipper kinase is a key regulator of the proliferation of malignant brain tumors, including brain tumor stem cells
    • I. Nakano, M. Masterman-Smith, and K. Saigusa Maternal embryonic leucine zipper kinase is a key regulator of the proliferation of malignant brain tumors, including brain tumor stem cells J Neurosci Res 86 2008 48 60
    • (2008) J Neurosci Res , vol.86 , pp. 48-60
    • Nakano, I.1    Masterman-Smith, M.2    Saigusa, K.3
  • 200
    • 0032412467 scopus 로고    scopus 로고
    • The significance of the expression of tumor suppressor gene DCC in human gliomas
    • K. Nakatani, N. Yoshimi, and H. Mori The significance of the expression of tumor suppressor gene DCC in human gliomas J Neurooncol 40 1998 237 242
    • (1998) J Neurooncol , vol.40 , pp. 237-242
    • Nakatani, K.1    Yoshimi, N.2    Mori, H.3
  • 201
    • 32244440850 scopus 로고    scopus 로고
    • Increased expression of 5-lipoxygenase in high-grade astrocytomas
    • [discussion-54]
    • N. Nathoo, R.A. Prayson, and J. Bondar Increased expression of 5-lipoxygenase in high-grade astrocytomas Neurosurgery 58 2006 347 354 [discussion-54]
    • (2006) Neurosurgery , vol.58 , pp. 347-354
    • Nathoo, N.1    Prayson, R.A.2    Bondar, J.3
  • 202
    • 0031679407 scopus 로고    scopus 로고
    • Survival of patients with glioblastoma multiforme is not influenced by altered expression of p16, p53, EGFR, MDM2 or Bcl-2 genes
    • E.W. Newcomb, H. Cohen, and S.R. Lee Survival of patients with glioblastoma multiforme is not influenced by altered expression of p16, p53, EGFR, MDM2 or Bcl-2 genes Brain Pathol 8 1998 655 667
    • (1998) Brain Pathol , vol.8 , pp. 655-667
    • Newcomb, E.W.1    Cohen, H.2    Lee, S.R.3
  • 203
    • 0642369915 scopus 로고    scopus 로고
    • Involvement of apolipoprotein e in glioblastoma: Immunohistochemistry and clinical outcome
    • J.A.R. Nicoll, E. Zunarelli, and R. Rampling Involvement of apolipoprotein E in glioblastoma: immunohistochemistry and clinical outcome Neuroreport 14 2003 1923 1926
    • (2003) Neuroreport , vol.14 , pp. 1923-1926
    • Nicoll, J.A.R.1    Zunarelli, E.2    Rampling, R.3
  • 204
    • 20144389740 scopus 로고    scopus 로고
    • Integrated array-comparative genomic hybridization and expression array profiles identify clinically relevant molecular subtypes of glioblastoma
    • J.M. Nigro, A. Misra, and L. Zhang Integrated array-comparative genomic hybridization and expression array profiles identify clinically relevant molecular subtypes of glioblastoma Cancer Res 65 2005 1678 1686
    • (2005) Cancer Res , vol.65 , pp. 1678-1686
    • Nigro, J.M.1    Misra, A.2    Zhang, L.3
  • 205
    • 70349653793 scopus 로고    scopus 로고
    • IDH1 mutations as molecular signature and predictive factor of secondary glioblastomas
    • S. Nobusawa, T. Watanabe, and P. Kleihues IDH1 mutations as molecular signature and predictive factor of secondary glioblastomas Clin Cancer Res 15 2009 6002 6007
    • (2009) Clin Cancer Res , vol.15 , pp. 6002-6007
    • Nobusawa, S.1    Watanabe, T.2    Kleihues, P.3
  • 206
    • 33745739440 scopus 로고    scopus 로고
    • Diagnostic and prognostic value of glycosyltransferase mRNA in glioblastoma multiforme patients
    • J.L. Oblinger, D.K. Pearl, and C.L. Boardman Diagnostic and prognostic value of glycosyltransferase mRNA in glioblastoma multiforme patients Neuropathol Appl Neurobiol 32 2006 410 418
    • (2006) Neuropathol Appl Neurobiol , vol.32 , pp. 410-418
    • Oblinger, J.L.1    Pearl, D.K.2    Boardman, C.L.3
  • 207
    • 0033499079 scopus 로고    scopus 로고
    • Vascular endothelial growth factor (VEGF) in astrocytic gliomas-a prognostic factor?
    • R.D. Oehring, M. Miletic, and M.M. Valter Vascular endothelial growth factor (VEGF) in astrocytic gliomas-a prognostic factor? J Neurooncol 45 1999 117 125
    • (1999) J Neurooncol , vol.45 , pp. 117-125
    • Oehring, R.D.1    Miletic, M.2    Valter, M.M.3
  • 208
    • 4944255253 scopus 로고    scopus 로고
    • Genetic pathways to glioblastoma: A population-based study
    • H. Ohgaki, P. Dessen, and B. Jourde Genetic pathways to glioblastoma: a population-based study Cancer Res 64 2004 6892 6899
    • (2004) Cancer Res , vol.64 , pp. 6892-6899
    • Ohgaki, H.1    Dessen, P.2    Jourde, B.3
  • 209
    • 20344407807 scopus 로고    scopus 로고
    • Population-based studies on incidence, survival rates, and genetic alterations in astrocytic and oligodendroglial gliomas
    • H. Ohgaki, and P. Kleihues Population-based studies on incidence, survival rates, and genetic alterations in astrocytic and oligodendroglial gliomas J Neuropathol Exp Neurol 64 2005 479 489
    • (2005) J Neuropathol Exp Neurol , vol.64 , pp. 479-489
    • Ohgaki, H.1    Kleihues, P.2
  • 210
    • 58149340463 scopus 로고    scopus 로고
    • Cancer stem cell analysis and clinical outcome in patients with glioblastoma multiforme
    • R. Pallini, L. Ricci-Vitiani, and G.L. Banna Cancer stem cell analysis and clinical outcome in patients with glioblastoma multiforme Clin Cancer Res 14 2008 8205 8212
    • (2008) Clin Cancer Res , vol.14 , pp. 8205-8212
    • Pallini, R.1    Ricci-Vitiani, L.2    Banna, G.L.3
  • 211
    • 66149128126 scopus 로고    scopus 로고
    • The receptor interacting protein 1 inhibits p53 induction through NF-kappaB activation and confers a worse prognosis in glioblastoma
    • S. Park, K.J. Hatanpaa, and Y. Xie The receptor interacting protein 1 inhibits p53 induction through NF-kappaB activation and confers a worse prognosis in glioblastoma Cancer Res 69 2009 2809 2816
    • (2009) Cancer Res , vol.69 , pp. 2809-2816
    • Park, S.1    Hatanpaa, K.J.2    Xie, Y.3
  • 212
    • 34250189213 scopus 로고    scopus 로고
    • Epidermal growth factor receptor variant III status defines clinically distinct subtypes of glioblastoma
    • C.E. Pelloski, K.V. Ballman, and A.F. Furth Epidermal growth factor receptor variant III status defines clinically distinct subtypes of glioblastoma J Clin Oncol 25 2007 2288 2294
    • (2007) J Clin Oncol , vol.25 , pp. 2288-2294
    • Pelloski, C.E.1    Ballman, K.V.2    Furth, A.F.3
  • 213
    • 33746046387 scopus 로고    scopus 로고
    • Prognostic associations of activated mitogen-activated protein kinase and Akt pathways in glioblastoma
    • C.E. Pelloski, E. Lin, and L. Zhang Prognostic associations of activated mitogen-activated protein kinase and Akt pathways in glioblastoma Clin Cancer Res 12 2006 3935 3941
    • (2006) Clin Cancer Res , vol.12 , pp. 3935-3941
    • Pelloski, C.E.1    Lin, E.2    Zhang, L.3
  • 214
    • 33846496221 scopus 로고    scopus 로고
    • Cyclooxygenase-2 expression in astrocytomas. Relationship with microvascular parameters, angiogenic factors expression and survival
    • M. Perdiki, P. Korkolopoulou, and I. Thymara Cyclooxygenase-2 expression in astrocytomas. Relationship with microvascular parameters, angiogenic factors expression and survival Mol Cell Biochem 295 2007 75 83
    • (2007) Mol Cell Biochem , vol.295 , pp. 75-83
    • Perdiki, M.1    Korkolopoulou, P.2    Thymara, I.3
  • 215
    • 73949090337 scopus 로고    scopus 로고
    • High incidence of MGMT and RARbeta promoter methylation in primary glioblastomas: Association with histopathological characteristics, inflammatory mediators and clinical outcome
    • C. Piperi, M.S. Themistocleous, and G.A. Papavassiliou High incidence of MGMT and RARbeta promoter methylation in primary glioblastomas: association with histopathological characteristics, inflammatory mediators and clinical outcome Mol Med 16 2009 1 9
    • (2009) Mol Med , vol.16 , pp. 1-9
    • Piperi, C.1    Themistocleous, M.S.2    Papavassiliou, G.A.3
  • 216
    • 53749087689 scopus 로고    scopus 로고
    • Relationship between gene expression and enhancement in glioblastoma multiforme: Exploratory DNA microarray analysis
    • W.B. Pope, J.H. Chen, and J. Dong Relationship between gene expression and enhancement in glioblastoma multiforme: exploratory DNA microarray analysis Radiology 249 2008 268 277
    • (2008) Radiology , vol.249 , pp. 268-277
    • Pope, W.B.1    Chen, J.H.2    Dong, J.3
  • 217
    • 21344462864 scopus 로고    scopus 로고
    • No prognostic impact of survivin expression in glioblastoma
    • M. Preusser, E. Gelpi, and R. Matej No prognostic impact of survivin expression in glioblastoma Acta Neuropathol 109 2005 534 538
    • (2005) Acta Neuropathol , vol.109 , pp. 534-538
    • Preusser, M.1    Gelpi, E.2    Matej, R.3
  • 218
    • 33745298443 scopus 로고    scopus 로고
    • Histopathologic assessment of hot-spot microvessel density and vascular patterns in glioblastoma: Poor observer agreement limits clinical utility as prognostic factors: A translational research project of the European Organization for Research and Treatment of Cancer Brain Tumor Group
    • M. Preusser, H. Heinzl, and E. Gelpi Histopathologic assessment of hot-spot microvessel density and vascular patterns in glioblastoma: Poor observer agreement limits clinical utility as prognostic factors: a translational research project of the European Organization for Research and Treatment of Cancer Brain Tumor Group Cancer 107 2006 162 170
    • (2006) Cancer , vol.107 , pp. 162-170
    • Preusser, M.1    Heinzl, H.2    Gelpi, E.3
  • 219
    • 9444290731 scopus 로고    scopus 로고
    • Presence of D110 antigen expressing immunocompetent cells in glioblastoma associates with prolonged survival
    • M. Preusser, T. Strobel, and P. Birner Presence of D110 antigen expressing immunocompetent cells in glioblastoma associates with prolonged survival Neuropathol Appl Neurobiol 30 2004 608 614
    • (2004) Neuropathol Appl Neurobiol , vol.30 , pp. 608-614
    • Preusser, M.1    Strobel, T.2    Birner, P.3
  • 220
    • 0034321968 scopus 로고    scopus 로고
    • Patterns of expression of Rb and p16 in astrocytic gliomas, and correlation with survival
    • V.K. Puduvalli, A.P. Kyritsis, and K.R. Hess Patterns of expression of Rb and p16 in astrocytic gliomas, and correlation with survival Int J Oncol 17 2000 963 969
    • (2000) Int J Oncol , vol.17 , pp. 963-969
    • Puduvalli, V.K.1    Kyritsis, A.P.2    Hess, K.R.3
  • 221
    • 25844521171 scopus 로고    scopus 로고
    • Epidermal growth factor receptor amplification does not have prognostic significance in patients with glioblastoma multiforme
    • A.L. Quan, G.H. Barnett, and S.Y. Lee Epidermal growth factor receptor amplification does not have prognostic significance in patients with glioblastoma multiforme Int J Radiat Oncol Biol Phys 63 2005 695 703
    • (2005) Int J Radiat Oncol Biol Phys , vol.63 , pp. 695-703
    • Quan, A.L.1    Barnett, G.H.2    Lee, S.Y.3
  • 222
    • 19544368188 scopus 로고    scopus 로고
    • Estimating cancer survival and clinical outcome based on genetic tumor progression scores
    • J. Rahnenfuhrer, N. Beerenwinkel, and W.A. Schulz Estimating cancer survival and clinical outcome based on genetic tumor progression scores Bioinformatics 21 2005 2438 2446
    • (2005) Bioinformatics , vol.21 , pp. 2438-2446
    • Rahnenfuhrer, J.1    Beerenwinkel, N.2    Schulz, W.A.3
  • 223
    • 3242881204 scopus 로고    scopus 로고
    • Prognostic value of Mdm2, p53 and p16 in patients with astrocytomas
    • S.M. Ranuncolo, M. Varela, and A. Morandi Prognostic value of Mdm2, p53 and p16 in patients with astrocytomas J Neurooncol 68 2004 113 121
    • (2004) J Neurooncol , vol.68 , pp. 113-121
    • Ranuncolo, S.M.1    Varela, M.2    Morandi, A.3
  • 224
    • 1642453727 scopus 로고    scopus 로고
    • Identification of necrosis-associated genes in glioblastoma by cDNA microarray analysis
    • S.M. Raza, G.N. Fuller, and C.H. Rhee Identification of necrosis-associated genes in glioblastoma by cDNA microarray analysis Clin Cancer Res 10 2004 212 221
    • (2004) Clin Cancer Res , vol.10 , pp. 212-221
    • Raza, S.M.1    Fuller, G.N.2    Rhee, C.H.3
  • 225
    • 0035712570 scopus 로고    scopus 로고
    • The prognostic value of tumor markers in patients with glioblastoma multiforme: Analysis of 32 patients and review of the literature
    • J.F. Reavey-Cantwell, R.I. Haroun, and M. Zahurak The prognostic value of tumor markers in patients with glioblastoma multiforme: analysis of 32 patients and review of the literature J Neurooncol 55 2001 195 204
    • (2001) J Neurooncol , vol.55 , pp. 195-204
    • Reavey-Cantwell, J.F.1    Haroun, R.I.2    Zahurak, M.3
  • 226
    • 56149120031 scopus 로고    scopus 로고
    • PBEF1/NAmPRTase/Visfatin: A potential malignant astrocytoma/glioblastoma serum marker with prognostic value
    • P.S. Reddy, S. Umesh, and B. Thota PBEF1/NAmPRTase/Visfatin: a potential malignant astrocytoma/glioblastoma serum marker with prognostic value Cancer Biol Ther 7 2008 663 668
    • (2008) Cancer Biol Ther , vol.7 , pp. 663-668
    • Reddy, P.S.1    Umesh, S.2    Thota, B.3
  • 227
    • 49649087701 scopus 로고    scopus 로고
    • Novel glioblastoma markers with diagnostic and prognostic value identified through transcriptome analysis
    • S.P. Reddy, R. Britto, and K. Vinnakota Novel glioblastoma markers with diagnostic and prognostic value identified through transcriptome analysis Clin Cancer Res 14 2008 2978 2987
    • (2008) Clin Cancer Res , vol.14 , pp. 2978-2987
    • Reddy, S.P.1    Britto, R.2    Vinnakota, K.3
  • 228
    • 0035108757 scopus 로고    scopus 로고
    • The level of manganese superoxide dismutase content is an independent prognostic factor for glioblastoma. Biological mechanisms and clinical implications
    • F. Ria, M. Landriscina, and F. Remiddi The level of manganese superoxide dismutase content is an independent prognostic factor for glioblastoma. Biological mechanisms and clinical implications Br J Cancer 84 2001 529 534
    • (2001) Br J Cancer , vol.84 , pp. 529-534
    • Ria, F.1    Landriscina, M.2    Remiddi, F.3
  • 229
    • 2642510847 scopus 로고    scopus 로고
    • The role of apoptosis, cell proliferation index, bcl-2, and p53 in glioblastoma prognosis
    • Mde.C. Ribeiro, L.M. Coutinho, and A. Hilbig The role of apoptosis, cell proliferation index, bcl-2, and p53 in glioblastoma prognosis Arq Neuropsiquiatr 62 2004 262 270
    • (2004) Arq Neuropsiquiatr , vol.62 , pp. 262-270
    • Ribeiro Mde., C.1    Coutinho, L.M.2    Hilbig, A.3
  • 230
    • 20144376240 scopus 로고    scopus 로고
    • Gene expression profiling and genetic markers in glioblastoma survival
    • J.N. Rich, C. Hans, and B. Jones Gene expression profiling and genetic markers in glioblastoma survival Cancer Res 65 2005 4051 4058
    • (2005) Cancer Res , vol.65 , pp. 4051-4058
    • Rich, J.N.1    Hans, C.2    Jones, B.3
  • 231
    • 75849146316 scopus 로고    scopus 로고
    • MGMT promoter methylation is predictive of response to radiotherapy and prognostic in the absence of adjuvant alkylating chemotherapy for glioblastoma
    • A.L. Rivera, C.E. Pelloski, and M.R. Gilbert MGMT promoter methylation is predictive of response to radiotherapy and prognostic in the absence of adjuvant alkylating chemotherapy for glioblastoma Neuro Oncol 12 2009 116 121
    • (2009) Neuro Oncol , vol.12 , pp. 116-121
    • Rivera, A.L.1    Pelloski, C.E.2    Gilbert, M.R.3
  • 232
    • 58049193062 scopus 로고    scopus 로고
    • Polymorphism in the microglial cell-mobilizing CX3CR1 gene is associated with survival in patients with glioblastoma
    • M. Rodero, Y. Marie, and M. Coudert Polymorphism in the microglial cell-mobilizing CX3CR1 gene is associated with survival in patients with glioblastoma J Clin Oncol 26 2008 5957 5964
    • (2008) J Clin Oncol , vol.26 , pp. 5957-5964
    • Rodero, M.1    Marie, Y.2    Coudert, M.3
  • 233
    • 37549037792 scopus 로고    scopus 로고
    • MGMT immunohistochemical expression and promoter methylation in human glioblastoma
    • F.J. Rodriguez, S.N. Thibodeau, and R.B. Jenkins MGMT immunohistochemical expression and promoter methylation in human glioblastoma Appl Immunohistochem Mol Morphol 16 2008 59 65
    • (2008) Appl Immunohistochem Mol Morphol , vol.16 , pp. 59-65
    • Rodriguez, F.J.1    Thibodeau, S.N.2    Jenkins, R.B.3
  • 234
    • 27944500223 scopus 로고    scopus 로고
    • Fascin expression in 90 patients with glioblastoma multiforme
    • A.A. Roma, and R.A. Prayson Fascin expression in 90 patients with glioblastoma multiforme Ann Diagn Pathol 9 2005 307 311
    • (2005) Ann Diagn Pathol , vol.9 , pp. 307-311
    • Roma, A.A.1    Prayson, R.A.2
  • 235
    • 41149083107 scopus 로고    scopus 로고
    • Identification of survival-related genes of the phosphatidylinositol 3′-kinase signaling pathway in glioblastoma multiforme
    • Y. Ruano, M. Mollejo, and F.I. Camacho Identification of survival-related genes of the phosphatidylinositol 3′-kinase signaling pathway in glioblastoma multiforme Cancer 112 2008 1575 1584
    • (2008) Cancer , vol.112 , pp. 1575-1584
    • Ruano, Y.1    Mollejo, M.2    Camacho, F.I.3
  • 236
    • 58849087233 scopus 로고    scopus 로고
    • Worse outcome in primary glioblastoma multiforme with concurrent epidermal growth factor receptor and p53 alteration
    • Y. Ruano, T. Ribalta, and A.R. de Lope Worse outcome in primary glioblastoma multiforme with concurrent epidermal growth factor receptor and p53 alteration Am J Clin Pathol 131 2009 257 263
    • (2009) Am J Clin Pathol , vol.131 , pp. 257-263
    • Ruano, Y.1    Ribalta, T.2    De Lope, A.R.3
  • 237
    • 57749180408 scopus 로고    scopus 로고
    • MGMT promoter hypermethylation correlates with a survival benefit from temozolomide in patients with recurrent anaplastic astrocytoma but not glioblastoma
    • J. Sadones, A. Michotte, and P. Veld MGMT promoter hypermethylation correlates with a survival benefit from temozolomide in patients with recurrent anaplastic astrocytoma but not glioblastoma Eur J Cancer 45 2009 146 153
    • (2009) Eur J Cancer , vol.45 , pp. 146-153
    • Sadones, J.1    Michotte, A.2    Veld, P.3
  • 238
    • 42149114566 scopus 로고    scopus 로고
    • Experimental anti-angiogenesis causes upregulation of genes associated with poor survival in glioblastoma
    • A. Saidi, S. Javerzat, and A. Bellahcene Experimental anti-angiogenesis causes upregulation of genes associated with poor survival in glioblastoma Int J Cancer 122 2008 2187 2198
    • (2008) Int J Cancer , vol.122 , pp. 2187-2198
    • Saidi, A.1    Javerzat, S.2    Bellahcene, A.3
  • 239
    • 28444478038 scopus 로고    scopus 로고
    • Overexpressed Skp2 within 5p amplification detected by array-based comparative genomic hybridization is associated with poor prognosis of glioblastomas
    • K. Saigusa, N. Hashimoto, and H. Tsuda Overexpressed Skp2 within 5p amplification detected by array-based comparative genomic hybridization is associated with poor prognosis of glioblastomas Cancer Sci 96 2005 676 683
    • (2005) Cancer Sci , vol.96 , pp. 676-683
    • Saigusa, K.1    Hashimoto, N.2    Tsuda, H.3
  • 240
    • 33845698912 scopus 로고    scopus 로고
    • Expression of nine tumour antigens in a series of human glioblastoma multiforme: Interest of EGFRvIII, IL-13Ralpha2, gp100 and TRP-2 for immunotherapy
    • S. Saikali, T. Avril, and B. Collet Expression of nine tumour antigens in a series of human glioblastoma multiforme: interest of EGFRvIII, IL-13Ralpha2, gp100 and TRP-2 for immunotherapy J Neurooncol 81 2007 139 148
    • (2007) J Neurooncol , vol.81 , pp. 139-148
    • Saikali, S.1    Avril, T.2    Collet, B.3
  • 241
    • 33645837873 scopus 로고    scopus 로고
    • Prognosis of cerebellar glioblastomas: Correlation between prognosis and immunoreactivity for epidermal growth factor receptor compared with supratentorial glioblastomas
    • T. Saito, S. Hama, and Y. Kajiwara Prognosis of cerebellar glioblastomas: correlation between prognosis and immunoreactivity for epidermal growth factor receptor compared with supratentorial glioblastomas Anticancer Res 26 2006 1351 1357
    • (2006) Anticancer Res , vol.26 , pp. 1351-1357
    • Saito, T.1    Hama, S.2    Kajiwara, Y.3
  • 242
    • 0038737156 scopus 로고    scopus 로고
    • Intracavitary VEGF, bFGF, IL-8, IL-12 levels in primary and recurrent malignant glioma
    • A. Salmaggi, M. Eoli, and S. Frigerio Intracavitary VEGF, bFGF, IL-8, IL-12 levels in primary and recurrent malignant glioma J Neurooncol 62 2003 297 303
    • (2003) J Neurooncol , vol.62 , pp. 297-303
    • Salmaggi, A.1    Eoli, M.2    Frigerio, S.3
  • 243
    • 71749103630 scopus 로고    scopus 로고
    • Comparative immunohistochemical analysis of aurora-A and aurora-B expression in human glioblastomas. Associations with proliferative activity and clinicopathological features
    • V. Samaras, A. Stamatelli, and E. Samaras Comparative immunohistochemical analysis of aurora-A and aurora-B expression in human glioblastomas. Associations with proliferative activity and clinicopathological features Pathol Res Pract 205 2009 765 773
    • (2009) Pathol Res Pract , vol.205 , pp. 765-773
    • Samaras, V.1    Stamatelli, A.2    Samaras, E.3
  • 244
    • 35848937194 scopus 로고    scopus 로고
    • Expression level of ECT2 proto-oncogene correlates with prognosis in glioma patients
    • M. Sano, N. Genkai, and N. Yajima Expression level of ECT2 proto-oncogene correlates with prognosis in glioma patients Oncol Rep 16 2006 1093 1098
    • (2006) Oncol Rep , vol.16 , pp. 1093-1098
    • Sano, M.1    Genkai, N.2    Yajima, N.3
  • 245
    • 58149202819 scopus 로고    scopus 로고
    • Polymorphisms in the interleukin-4 receptor gene are associated with better survival in patients with glioblastoma
    • M.E. Scheurer, E. Amirian, and Y. Cao Polymorphisms in the interleukin-4 receptor gene are associated with better survival in patients with glioblastoma Clin Cancer Res 14 2008 6640 6646
    • (2008) Clin Cancer Res , vol.14 , pp. 6640-6646
    • Scheurer, M.E.1    Amirian, E.2    Cao, Y.3
  • 246
    • 0034488325 scopus 로고    scopus 로고
    • Analysis of mdm2 and p53 gene alterations in glioblastomas and its correlation with clinical factors
    • M. Schiebe, P. Ohneseit, and W. Hoffmann Analysis of mdm2 and p53 gene alterations in glioblastomas and its correlation with clinical factors J Neurooncol 49 2000 197 203
    • (2000) J Neurooncol , vol.49 , pp. 197-203
    • Schiebe, M.1    Ohneseit, P.2    Hoffmann, W.3
  • 247
    • 0035039056 scopus 로고    scopus 로고
    • Loss of heterozygosity at 11p15 and p53 alterations in malignant gliomas
    • M. Schiebe, P. Ohneseit, and W. Hoffmann Loss of heterozygosity at 11p15 and p53 alterations in malignant gliomas J Cancer Res Clin Oncol 127 2001 325 328
    • (2001) J Cancer Res Clin Oncol , vol.127 , pp. 325-328
    • Schiebe, M.1    Ohneseit, P.2    Hoffmann, W.3
  • 248
    • 71149088947 scopus 로고    scopus 로고
    • Comparative analysis of annexin-1 in neuroepithelial tumors shows altered expression with the grade of malignancy but is not associated with survival
    • J. Schittenhelm, K. Trautmann, and G. Tabatabai Comparative analysis of annexin-1 in neuroepithelial tumors shows altered expression with the grade of malignancy but is not associated with survival Mod Pathol 22 2009 1600 1611
    • (2009) Mod Pathol , vol.22 , pp. 1600-1611
    • Schittenhelm, J.1    Trautmann, K.2    Tabatabai, G.3
  • 249
    • 0036201832 scopus 로고    scopus 로고
    • Impact of genotype and morphology on the prognosis of glioblastoma
    • M.C. Schmidt, S. Antweiler, and N. Urban Impact of genotype and morphology on the prognosis of glioblastoma J Neuropathol Exp Neurol 61 2002 321 328
    • (2002) J Neuropathol Exp Neurol , vol.61 , pp. 321-328
    • Schmidt, M.C.1    Antweiler, S.2    Urban, N.3
  • 250
    • 34250781164 scopus 로고    scopus 로고
    • Prognostic significance of co-overexpression of the EGFR/IGFBP-2/HIF-2A genes in astrocytomas
    • C.A. Scrideli, C.G. Carlotti Jr., and J.F. Mata Prognostic significance of co-overexpression of the EGFR/IGFBP-2/HIF-2A genes in astrocytomas J Neurooncol 83 2007 233 239
    • (2007) J Neurooncol , vol.83 , pp. 233-239
    • Scrideli, C.A.1    Carlotti, Jr.C.G.2    Mata, J.F.3
  • 251
    • 77953230937 scopus 로고    scopus 로고
    • A genome-wide RNA interference screen reveals an essential CREB3L2-ATF5-MCL1 survival pathway in malignant glioma with therapeutic implications
    • Z. Sheng, L. Li, and L.J. Zhu A genome-wide RNA interference screen reveals an essential CREB3L2-ATF5-MCL1 survival pathway in malignant glioma with therapeutic implications Nat Med 16 2010 671 677
    • (2010) Nat Med , vol.16 , pp. 671-677
    • Sheng, Z.1    Li, L.2    Zhu, L.J.3
  • 252
    • 25844464196 scopus 로고    scopus 로고
    • Genetic analyses for predictors of radiation response in glioblastoma
    • H.A. Shih, R.A. Betensky, and M.V. Dorfman Genetic analyses for predictors of radiation response in glioblastoma Int J Radiat Oncol Biol Phys 63 2005 704 710
    • (2005) Int J Radiat Oncol Biol Phys , vol.63 , pp. 704-710
    • Shih, H.A.1    Betensky, R.A.2    Dorfman, M.V.3
  • 253
    • 0142188691 scopus 로고    scopus 로고
    • Prognostic value of epidermal growth factor receptor in patients with glioblastoma multiforme
    • N. Shinojima, K. Tada, and S. Shiraishi Prognostic value of epidermal growth factor receptor in patients with glioblastoma multiforme Cancer Res 63 2003 6962 6970
    • (2003) Cancer Res , vol.63 , pp. 6962-6970
    • Shinojima, N.1    Tada, K.2    Shiraishi, S.3
  • 254
    • 58149301357 scopus 로고    scopus 로고
    • Using gene expression profiling to identify a prognostic molecular spectrum in gliomas
    • M. Shirahata, S. Oba, and K. Iwao-Koizumi Using gene expression profiling to identify a prognostic molecular spectrum in gliomas Cancer Sci 100 2009 165 172
    • (2009) Cancer Sci , vol.100 , pp. 165-172
    • Shirahata, M.1    Oba, S.2    Iwao-Koizumi, K.3
  • 255
    • 0037099758 scopus 로고    scopus 로고
    • Influence of p53 mutations on prognosis of patients with glioblastoma
    • S. Shiraishi, K. Tada, and H. Nakamura Influence of p53 mutations on prognosis of patients with glioblastoma Cancer 95 2002 249 257
    • (2002) Cancer , vol.95 , pp. 249-257
    • Shiraishi, S.1    Tada, K.2    Nakamura, H.3
  • 256
    • 0035360795 scopus 로고    scopus 로고
    • Cyclooxygenase-2 expression in human gliomas: Prognostic significance and molecular correlations
    • T. Shono, P.J. Tofilon, and J.M. Bruner Cyclooxygenase-2 expression in human gliomas: prognostic significance and molecular correlations Cancer Res 61 2001 4375 4381
    • (2001) Cancer Res , vol.61 , pp. 4375-4381
    • Shono, T.1    Tofilon, P.J.2    Bruner, J.M.3
  • 257
    • 33847387994 scopus 로고    scopus 로고
    • Geminin: A good prognostic factor in high-grade astrocytic brain tumors
    • P. Shrestha, T. Saito, and S. Hama Geminin: a good prognostic factor in high-grade astrocytic brain tumors Cancer 109 2007 949 956
    • (2007) Cancer , vol.109 , pp. 949-956
    • Shrestha, P.1    Saito, T.2    Hama, S.3
  • 258
    • 60749127594 scopus 로고    scopus 로고
    • The angiopoietin 1/angiopoietin 2 balance as a prognostic marker in primary glioblastoma multiforme
    • M. Sie, M. Wagemakers, and G. Molema The angiopoietin 1/angiopoietin 2 balance as a prognostic marker in primary glioblastoma multiforme J Neurosurg 110 2009 147 155
    • (2009) J Neurosurg , vol.110 , pp. 147-155
    • Sie, M.1    Wagemakers, M.2    Molema, G.3
  • 259
    • 17444379728 scopus 로고    scopus 로고
    • Gamma-ray mutagen sensitivity and survival in patients with glioma
    • A.J. Sigurdson, M.L. Bondy, and K.R. Hess Gamma-ray mutagen sensitivity and survival in patients with glioma Clin Cancer Res 4 1998 3031 3035
    • (1998) Clin Cancer Res , vol.4 , pp. 3031-3035
    • Sigurdson, A.J.1    Bondy, M.L.2    Hess, K.R.3
  • 260
    • 0035111058 scopus 로고    scopus 로고
    • Analysis of complex relationships between age, p53, epidermal growth factor receptor, and survival in glioblastoma patients
    • M.L. Simmons, K.R. Lamborn, and M. Takahashi Analysis of complex relationships between age, p53, epidermal growth factor receptor, and survival in glioblastoma patients Cancer Res 61 2001 1122 1128
    • (2001) Cancer Res , vol.61 , pp. 1122-1128
    • Simmons, M.L.1    Lamborn, K.R.2    Takahashi, M.3
  • 261
    • 33845212332 scopus 로고    scopus 로고
    • Variant of the CHEK2 gene as a prognostic marker in glioblastoma multiforme
    • [discussion 85]
    • M. Simon, M. Ludwig, and R. Fimmers Variant of the CHEK2 gene as a prognostic marker in glioblastoma multiforme Neurosurgery 59 2006 1078 1085 [discussion 85]
    • (2006) Neurosurgery , vol.59 , pp. 1078-1085
    • Simon, M.1    Ludwig, M.2    Fimmers, R.3
  • 262
    • 27144456121 scopus 로고    scopus 로고
    • Expression of cyclooxygenase-2 and epidermal growth factor receptor in primary and recurrent glioblastoma multiforme
    • P. Sminia, T.R. Stoter, and P. van der Valk Expression of cyclooxygenase-2 and epidermal growth factor receptor in primary and recurrent glioblastoma multiforme J Cancer Res Clin Oncol 131 2005 653 661
    • (2005) J Cancer Res Clin Oncol , vol.131 , pp. 653-661
    • Sminia, P.1    Stoter, T.R.2    Van Der Valk, P.3
  • 263
    • 0033951824 scopus 로고    scopus 로고
    • Alterations of chromosome arms 1p and 19q as predictors of survival in oligodendrogliomas, astrocytomas, and mixed oligoastrocytomas
    • J.S. Smith, A. Perry, and T.J. Borell Alterations of chromosome arms 1p and 19q as predictors of survival in oligodendrogliomas, astrocytomas, and mixed oligoastrocytomas J Clin Oncol 18 2000 636 645
    • (2000) J Clin Oncol , vol.18 , pp. 636-645
    • Smith, J.S.1    Perry, A.2    Borell, T.J.3
  • 264
    • 0035880788 scopus 로고    scopus 로고
    • PTEN mutation, EGFR amplification, and outcome in patients with anaplastic astrocytoma and glioblastoma multiforme
    • J.S. Smith, I. Tachibana, and S.M. Passe PTEN mutation, EGFR amplification, and outcome in patients with anaplastic astrocytoma and glioblastoma multiforme J Natl Cancer Inst 93 2001 1246 1256
    • (2001) J Natl Cancer Inst , vol.93 , pp. 1246-1256
    • Smith, J.S.1    Tachibana, I.2    Passe, S.M.3
  • 265
    • 11344254330 scopus 로고    scopus 로고
    • Minichromosome maintenance protein 3 elicits a cancer-restricted immune response in patients with brain malignancies and is a strong independent predictor of survival in patients with anaplastic astrocytoma
    • A. Soling, M. Sackewitz, and M. Volkmar Minichromosome maintenance protein 3 elicits a cancer-restricted immune response in patients with brain malignancies and is a strong independent predictor of survival in patients with anaplastic astrocytoma Clin Cancer Res 11 2005 249 258
    • (2005) Clin Cancer Res , vol.11 , pp. 249-258
    • Soling, A.1    Sackewitz, M.2    Volkmar, M.3
  • 266
    • 70449521966 scopus 로고    scopus 로고
    • Long-term survivors of glioblastoma: Clinical features and molecular analysis
    • Y. Sonoda, T. Kumabe, and M. Watanabe Long-term survivors of glioblastoma: clinical features and molecular analysis Acta Neurochir (Wien) 151 2009 1349 1358
    • (2009) Acta Neurochir (Wien) , vol.151 , pp. 1349-1358
    • Sonoda, Y.1    Kumabe, T.2    Watanabe, M.3
  • 267
    • 75749109750 scopus 로고    scopus 로고
    • O6-Methylguanine DNA methyltransferase protein expression in tumor cells predicts outcome of temozolomide therapy in glioblastoma patients
    • S. Spiegl-Kreinecker, C. Pirker, and M. Filipits O6-Methylguanine DNA methyltransferase protein expression in tumor cells predicts outcome of temozolomide therapy in glioblastoma patients Neuro Oncol 12 2009 28 36
    • (2009) Neuro Oncol , vol.12 , pp. 28-36
    • Spiegl-Kreinecker, S.1    Pirker, C.2    Filipits, M.3
  • 268
    • 0037262853 scopus 로고    scopus 로고
    • Age-related expression of p53, Mdm2, EGFR and Msh2 in glioblastoma multiforme
    • A.M. Stark, H.H. Hugo, and P. Witzel Age-related expression of p53, Mdm2, EGFR and Msh2 in glioblastoma multiforme Zentralbl Neurochir 64 2003 30 36
    • (2003) Zentralbl Neurochir , vol.64 , pp. 30-36
    • Stark, A.M.1    Hugo, H.H.2    Witzel, P.3
  • 269
    • 4644314826 scopus 로고    scopus 로고
    • Aberrant methylation and down-regulation of TMS1/ASC in human glioblastoma
    • A.R. Stone, W. Bobo, and D.J. Brat Aberrant methylation and down-regulation of TMS1/ASC in human glioblastoma Am J Pathol 165 2004 1151 1161
    • (2004) Am J Pathol , vol.165 , pp. 1151-1161
    • Stone, A.R.1    Bobo, W.2    Brat, D.J.3
  • 270
    • 1842536981 scopus 로고    scopus 로고
    • Protein expression of Fas, Fas ligand, Bcl-2 and TGFbeta2 and correlation with survival in initial and recurrent human gliomas
    • R.J. Strege, C. Godt, and A.M. Stark Protein expression of Fas, Fas ligand, Bcl-2 and TGFbeta2 and correlation with survival in initial and recurrent human gliomas J Neurooncol 67 2004 29 39
    • (2004) J Neurooncol , vol.67 , pp. 29-39
    • Strege, R.J.1    Godt, C.2    Stark, A.M.3
  • 271
    • 0032999141 scopus 로고    scopus 로고
    • Immunohistochemical staining in tumor and endothelial cells is a new prognostic factor for survival in patients with brain tumors
    • T. Strojnik, J. Kos, and B. Zidanik Immunohistochemical staining in tumor and endothelial cells is a new prognostic factor for survival in patients with brain tumors Clin Cancer Res 5 1999 559 567
    • (1999) Clin Cancer Res , vol.5 , pp. 559-567
    • Strojnik, T.1    Kos, J.2    Zidanik, B.3
  • 272
    • 0034761379 scopus 로고    scopus 로고
    • Analysis of loss of heterozygosity on chromosome 10 in patients with malignant astrocytic tumors: Correlation with patient age and survival
    • K. Tada, S. Shiraishi, and T. Kamiryo Analysis of loss of heterozygosity on chromosome 10 in patients with malignant astrocytic tumors: correlation with patient age and survival J Neurosurg 95 2001 651 659
    • (2001) J Neurosurg , vol.95 , pp. 651-659
    • Tada, K.1    Shiraishi, S.2    Kamiryo, T.3
  • 273
    • 0032080417 scopus 로고    scopus 로고
    • Selective sensitivity to radiation of cerebral glioblastomas harboring p53 mutations
    • M. Tada, R. Matsumoto, and R.D. Iggo Selective sensitivity to radiation of cerebral glioblastomas harboring p53 mutations Cancer Res 58 1998 1793 1797
    • (1998) Cancer Res , vol.58 , pp. 1793-1797
    • Tada, M.1    Matsumoto, R.2    Iggo, R.D.3
  • 274
    • 23844474734 scopus 로고    scopus 로고
    • Positive and negative associations of human leukocyte antigen variants with the onset and prognosis of adult glioblastoma multiforme
    • J. Tang, W. Shao, and M.T. Dorak Positive and negative associations of human leukocyte antigen variants with the onset and prognosis of adult glioblastoma multiforme Cancer Epidemiol Biomarkers Prev 14 2005 2040 2044
    • (2005) Cancer Epidemiol Biomarkers Prev , vol.14 , pp. 2040-2044
    • Tang, J.1    Shao, W.2    Dorak, M.T.3
  • 275
    • 33747475496 scopus 로고    scopus 로고
    • Expression of autocrine motility factor mRNA is a poor prognostic factor in high-grade astrocytoma
    • Y. Tanizaki, Y. Sato, and H. Oka Expression of autocrine motility factor mRNA is a poor prognostic factor in high-grade astrocytoma Pathol Int 56 2006 510 515
    • (2006) Pathol Int , vol.56 , pp. 510-515
    • Tanizaki, Y.1    Sato, Y.2    Oka, H.3
  • 276
    • 33846804009 scopus 로고    scopus 로고
    • Interleukin-6 gene amplification and shortened survival in glioblastoma patients
    • A. Tchirkov, T. Khalil, and E. Chautard Interleukin-6 gene amplification and shortened survival in glioblastoma patients Br J Cancer 96 2007 474 476
    • (2007) Br J Cancer , vol.96 , pp. 474-476
    • Tchirkov, A.1    Khalil, T.2    Chautard, E.3
  • 277
    • 0037463232 scopus 로고    scopus 로고
    • Clinical implications of quantitative real-time RT-PCR analysis of hTERT gene expression in human gliomas
    • A. Tchirkov, C. Rolhion, and J.L. Kemeny Clinical implications of quantitative real-time RT-PCR analysis of hTERT gene expression in human gliomas Br J Cancer 88 2003 516 520
    • (2003) Br J Cancer , vol.88 , pp. 516-520
    • Tchirkov, A.1    Rolhion, C.2    Kemeny, J.L.3
  • 278
    • 35348883191 scopus 로고    scopus 로고
    • Coexpression of c-erbB 1-4 receptor proteins in human glioblastomas. An immunohistochemical study
    • S.H. Torp, S. Gulati, and E. Johannessen Coexpression of c-erbB 1-4 receptor proteins in human glioblastomas. An immunohistochemical study J Exp Clin Cancer Res 26 2007 353 359
    • (2007) J Exp Clin Cancer Res , vol.26 , pp. 353-359
    • Torp, S.H.1    Gulati, S.2    Johannessen, E.3
  • 279
    • 77952576092 scopus 로고    scopus 로고
    • Over-expression of neuroepithelial-transforming protein 1 confers poor prognosis of patients with gliomas
    • Y. Tu, J. Lu, and J. Fu Over-expression of neuroepithelial-transforming protein 1 confers poor prognosis of patients with gliomas Jpn J Clin Oncol 40 2010 388 394
    • (2010) Jpn J Clin Oncol , vol.40 , pp. 388-394
    • Tu, Y.1    Lu, J.2    Fu, J.3
  • 280
    • 7044226619 scopus 로고    scopus 로고
    • Ezrin expression in tissue microarray of primary and recurrent gliomas
    • O. Tynninen, O. Carpen, and J. Jaaskelainen Ezrin expression in tissue microarray of primary and recurrent gliomas Neuropathol Appl Neurobiol 30 2004 472 477
    • (2004) Neuropathol Appl Neurobiol , vol.30 , pp. 472-477
    • Tynninen, O.1    Carpen, O.2    Jaaskelainen, J.3
  • 281
    • 33947115905 scopus 로고    scopus 로고
    • Preferential expression and frequent IgG responses of a tumor antigen, SOX5, in glioma patients
    • R. Ueda, K. Yoshida, and T. Kawase Preferential expression and frequent IgG responses of a tumor antigen, SOX5, in glioma patients Int J Cancer 120 2007 1704 1711
    • (2007) Int J Cancer , vol.120 , pp. 1704-1711
    • Ueda, R.1    Yoshida, K.2    Kawase, T.3
  • 282
    • 70350052877 scopus 로고    scopus 로고
    • Clinical and immunohistochemical prognostic factors in adult glioblastoma patients
    • S. Umesh, A. Tandon, and V. Santosh Clinical and immunohistochemical prognostic factors in adult glioblastoma patients Clin Neuropathol 28 2009 362 372
    • (2009) Clin Neuropathol , vol.28 , pp. 362-372
    • Umesh, S.1    Tandon, A.2    Santosh, V.3
  • 283
    • 23844498431 scopus 로고    scopus 로고
    • Sphingosine kinase-1 expression correlates with poor survival of patients with glioblastoma multiforme: Roles of sphingosine kinase isoforms in growth of glioblastoma cell lines
    • J.R. Van Brocklyn, C.A. Jackson, and D.K. Pearl Sphingosine kinase-1 expression correlates with poor survival of patients with glioblastoma multiforme: roles of sphingosine kinase isoforms in growth of glioblastoma cell lines J Neuropathol Exp Neurol 64 2005 695 705
    • (2005) J Neuropathol Exp Neurol , vol.64 , pp. 695-705
    • Van Brocklyn, J.R.1    Jackson, C.A.2    Pearl, D.K.3
  • 284
    • 0036186336 scopus 로고    scopus 로고
    • Imbalance between apostain expression and proliferative index can predict survival in primary glioblastoma
    • [discussion 155-6]
    • J. Vaquero, M. Zurita, and S. Coca Imbalance between apostain expression and proliferative index can predict survival in primary glioblastoma Acta Neurochir (Wien) 144 2002 151 155 [discussion 155-6]
    • (2002) Acta Neurochir (Wien) , vol.144 , pp. 151-155
    • Vaquero, J.1    Zurita, M.2    Coca, S.3
  • 285
    • 0034076972 scopus 로고    scopus 로고
    • Prognostic significance of endothelial surface score and MIB-1 labeling index in glioblastoma
    • J. Vaquero, M. Zurita, and C. Morales Prognostic significance of endothelial surface score and MIB-1 labeling index in glioblastoma J Neurooncol 46 2000 11 16
    • (2000) J Neurooncol , vol.46 , pp. 11-16
    • Vaquero, J.1    Zurita, M.2    Morales, C.3
  • 286
    • 33845520633 scopus 로고    scopus 로고
    • The 61 A/G EGF polymorphism is functional but is neither a prognostic marker nor a risk factor for glioblastoma
    • E. Vauleon, N. Auger, and A. Benouaich-Amiel The 61 A/G EGF polymorphism is functional but is neither a prognostic marker nor a risk factor for glioblastoma Cancer Genet Cytogenet 172 2007 33 37
    • (2007) Cancer Genet Cytogenet , vol.172 , pp. 33-37
    • Vauleon, E.1    Auger, N.2    Benouaich-Amiel, A.3
  • 287
    • 73649123907 scopus 로고    scopus 로고
    • Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1
    • R.G. Verhaak, K.A. Hoadley, and E. Purdom Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1 Cancer Cell 17 2010 98 110
    • (2010) Cancer Cell , vol.17 , pp. 98-110
    • Verhaak, R.G.1    Hoadley, K.A.2    Purdom, E.3
  • 288
    • 33645737210 scopus 로고    scopus 로고
    • Survival prediction in patients with glioblastoma multiforme by human telomerase genetic variation
    • L. Wang, Q. Wei, and L.E. Wang Survival prediction in patients with glioblastoma multiforme by human telomerase genetic variation J Clin Oncol 24 2006 1627 1632
    • (2006) J Clin Oncol , vol.24 , pp. 1627-1632
    • Wang, L.1    Wei, Q.2    Wang, L.E.3
  • 289
    • 38749092525 scopus 로고    scopus 로고
    • Increased expression of EphA2 correlates with adverse outcome in primary and recurrent glioblastoma multiforme patients
    • L.F. Wang, E. Fokas, and M. Bieker Increased expression of EphA2 correlates with adverse outcome in primary and recurrent glioblastoma multiforme patients Oncol Rep 19 2008 151 156
    • (2008) Oncol Rep , vol.19 , pp. 151-156
    • Wang, L.F.1    Fokas, E.2    Bieker, M.3
  • 290
    • 34248194268 scopus 로고    scopus 로고
    • Expression pattern of the water channel aquaporin-4 in human gliomas is associated with blood-brain barrier disturbance but not with patient survival
    • A. Warth, P. Simon, and D. Capper Expression pattern of the water channel aquaporin-4 in human gliomas is associated with blood-brain barrier disturbance but not with patient survival J Neurosci Res 85 2007 1336 1346
    • (2007) J Neurosci Res , vol.85 , pp. 1336-1346
    • Warth, A.1    Simon, P.2    Capper, D.3
  • 291
    • 11144305238 scopus 로고    scopus 로고
    • O6-methylguanine-DNA methyltransferase methylation and TP53 mutation in malignant astrocytomas and their relationships with clinical course
    • T. Watanabe, Y. Katayama, and C. Komine O6-methylguanine-DNA methyltransferase methylation and TP53 mutation in malignant astrocytomas and their relationships with clinical course Int J Cancer 113 2005 581 587
    • (2005) Int J Cancer , vol.113 , pp. 581-587
    • Watanabe, T.1    Katayama, Y.2    Komine, C.3
  • 292
    • 77649259735 scopus 로고    scopus 로고
    • Evaluation of the prognostic value of CD44 in glioblastoma multiforme
    • K.C. Wei, C.Y. Huang, and P.Y. Chen Evaluation of the prognostic value of CD44 in glioblastoma multiforme Anticancer Res 30 2010 253 259
    • (2010) Anticancer Res , vol.30 , pp. 253-259
    • Wei, K.C.1    Huang, C.Y.2    Chen, P.Y.3
  • 293
    • 67649519724 scopus 로고    scopus 로고
    • Rad51 protein expression and survival in patients with glioblastoma multiforme
    • J.W. Welsh, R.K. Ellsworth, and R. Kumar Rad51 protein expression and survival in patients with glioblastoma multiforme Int J Radiat Oncol Biol Phys 74 2009 1251 1255
    • (2009) Int J Radiat Oncol Biol Phys , vol.74 , pp. 1251-1255
    • Welsh, J.W.1    Ellsworth, R.K.2    Kumar, R.3
  • 294
    • 67649442519 scopus 로고    scopus 로고
    • P15 promoter methylation - A novel prognostic marker in glioblastoma patients
    • S. Wemmert, M. Bettscheider, and S. Alt P15 promoter methylation - a novel prognostic marker in glioblastoma patients Int J Oncol 34 2009 1743 1748
    • (2009) Int J Oncol , vol.34 , pp. 1743-1748
    • Wemmert, S.1    Bettscheider, M.2    Alt, S.3
  • 295
    • 33644874646 scopus 로고    scopus 로고
    • Patients with high-grade gliomas harboring deletions of chromosomes 9p and 10q benefit from temozolomide treatment
    • S. Wemmert, R. Ketter, and J. Rahnenfuhrer Patients with high-grade gliomas harboring deletions of chromosomes 9p and 10q benefit from temozolomide treatment Neoplasia 7 2005 883 893
    • (2005) Neoplasia , vol.7 , pp. 883-893
    • Wemmert, S.1    Ketter, R.2    Rahnenfuhrer, J.3
  • 296
    • 4344627154 scopus 로고    scopus 로고
    • Comparative genomic hybridization analysis of astrocytomas: Prognostic and diagnostic implications
    • R.N. Wiltshire, J.E. Herndon 2nd, and A. Lloyd Comparative genomic hybridization analysis of astrocytomas: prognostic and diagnostic implications J Mol Diagn 6 2004 166 179
    • (2004) J Mol Diagn , vol.6 , pp. 166-179
    • Wiltshire, R.N.1    Herndon, J.E.2    Lloyd, A.3
  • 297
    • 33646242019 scopus 로고    scopus 로고
    • Serum IgE, tumor epidermal growth factor receptor expression, and inherited polymorphisms associated with glioma survival
    • M. Wrensch, J.K. Wiencke, and J. Wiemels Serum IgE, tumor epidermal growth factor receptor expression, and inherited polymorphisms associated with glioma survival Cancer Res 66 2006 4531 4541
    • (2006) Cancer Res , vol.66 , pp. 4531-4541
    • Wrensch, M.1    Wiencke, J.K.2    Wiemels, J.3
  • 298
    • 1642350329 scopus 로고    scopus 로고
    • Levels of expression of CYR61 and CTGF are prognostic for tumor progression and survival of individuals with gliomas
    • D. Xie, D. Yin, and H.J. Wang Levels of expression of CYR61 and CTGF are prognostic for tumor progression and survival of individuals with gliomas Clin Cancer Res 10 2004 2072 2081
    • (2004) Clin Cancer Res , vol.10 , pp. 2072-2081
    • Xie, D.1    Yin, D.2    Wang, H.J.3
  • 299
    • 58049193929 scopus 로고    scopus 로고
    • Hedgehog signaling regulates brain tumor-initiating cell proliferation and portends shorter survival for patients with PTEN-coexpressing glioblastomas
    • Q. Xu, X. Yuan, and G. Liu Hedgehog signaling regulates brain tumor-initiating cell proliferation and portends shorter survival for patients with PTEN-coexpressing glioblastomas Stem Cells 26 2008 3018 3026
    • (2008) Stem Cells , vol.26 , pp. 3018-3026
    • Xu, Q.1    Yuan, X.2    Liu, G.3
  • 300
    • 54849188000 scopus 로고    scopus 로고
    • Relevance of MSP assay for the detection of MGMT promoter hypermethylation in glioblastomas
    • K. Yachi, T. Watanabe, and T. Ohta Relevance of MSP assay for the detection of MGMT promoter hypermethylation in glioblastomas Int J Oncol 33 2008 469 475
    • (2008) Int J Oncol , vol.33 , pp. 469-475
    • Yachi, K.1    Watanabe, T.2    Ohta, T.3
  • 301
    • 67651030609 scopus 로고    scopus 로고
    • Monosomy of chromosome 10 associated with dysregulation of epidermal growth factor signaling in glioblastomas
    • A.K. Yadav, J.J. Renfrow, and D.M. Scholtens Monosomy of chromosome 10 associated with dysregulation of epidermal growth factor signaling in glioblastomas Jama 302 2009 276 289
    • (2009) Jama , vol.302 , pp. 276-289
    • Yadav, A.K.1    Renfrow, J.J.2    Scholtens, D.M.3
  • 302
    • 0036212775 scopus 로고    scopus 로고
    • Fibroblast growth factor receptor (FGFR) 4 correlated with the malignancy of human astrocytomas
    • S.M. Yamada, S. Yamada, and Y. Hayashi Fibroblast growth factor receptor (FGFR) 4 correlated with the malignancy of human astrocytomas Neurol Res 24 2002 244 248
    • (2002) Neurol Res , vol.24 , pp. 244-248
    • Yamada, S.M.1    Yamada, S.2    Hayashi, Y.3
  • 303
    • 27244431905 scopus 로고    scopus 로고
    • Prognostic significance of microvessel density determined by an anti-CD105/endoglin monoclonal antibody in astrocytic tumors: Comparison with an anti-CD31 monoclonal antibody
    • Y. Yao, T. Kubota, and H. Takeuchi Prognostic significance of microvessel density determined by an anti-CD105/endoglin monoclonal antibody in astrocytic tumors: comparison with an anti-CD31 monoclonal antibody Neuropathology 25 2005 201 206
    • (2005) Neuropathology , vol.25 , pp. 201-206
    • Yao, Y.1    Kubota, T.2    Takeuchi, H.3
  • 304
    • 66349133436 scopus 로고    scopus 로고
    • High-resolution genomic copy number profiling of glioblastoma multiforme by single nucleotide polymorphism DNA microarray
    • D. Yin, S. Ogawa, and N. Kawamata High-resolution genomic copy number profiling of glioblastoma multiforme by single nucleotide polymorphism DNA microarray Mol Cancer Res 7 2009 665 677
    • (2009) Mol Cancer Res , vol.7 , pp. 665-677
    • Yin, D.1    Ogawa, S.2    Kawamata, N.3
  • 305
    • 77951241291 scopus 로고    scopus 로고
    • Sphingosine-1-phosphate receptor type 1 regulates glioma cell proliferation and correlates with patient survival
    • Y. Yoshida, M. Nakada, and N. Sugimoto Sphingosine-1-phosphate receptor type 1 regulates glioma cell proliferation and correlates with patient survival Int J Cancer 126 2010 2341 2352
    • (2010) Int J Cancer , vol.126 , pp. 2341-2352
    • Yoshida, Y.1    Nakada, M.2    Sugimoto, N.3
  • 306
    • 61649116731 scopus 로고    scopus 로고
    • Common polymorphisms in the MDM2 and TP53 genes and the relationship between TP53 mutations and patient outcomes in glioblastomas
    • I. Zawlik, D. Kita, and S. Vaccarella Common polymorphisms in the MDM2 and TP53 genes and the relationship between TP53 mutations and patient outcomes in glioblastomas Brain Pathol 19 2009 188 194
    • (2009) Brain Pathol , vol.19 , pp. 188-194
    • Zawlik, I.1    Kita, D.2    Vaccarella, S.3
  • 307
    • 55449122220 scopus 로고    scopus 로고
    • Promoter methylation and polymorphisms of the MGMT gene in glioblastomas: A population-based study
    • I. Zawlik, S. Vaccarella, and D. Kita Promoter methylation and polymorphisms of the MGMT gene in glioblastomas: a population-based study Neuroepidemiology 32 2009 21 29
    • (2009) Neuroepidemiology , vol.32 , pp. 21-29
    • Zawlik, I.1    Vaccarella, S.2    Kita, D.3
  • 308
    • 67650882239 scopus 로고    scopus 로고
    • A systems biology-based gene expression classifier of glioblastoma predicts survival with solid tumors
    • J. Zhang, B. Liu, and X. Jiang A systems biology-based gene expression classifier of glioblastoma predicts survival with solid tumors PLoS One 4 2009 e6274
    • (2009) PLoS One , vol.4 , pp. e6274
    • Zhang, J.1    Liu, B.2    Jiang, X.3
  • 309
    • 70449711757 scopus 로고    scopus 로고
    • Genetic alterations and signaling pathways in the evolution of gliomas
    • H. Ohgaki, and P. Kleihues Genetic alterations and signaling pathways in the evolution of gliomas Cancer Science 100 2009 2235 2241
    • (2009) Cancer Science , vol.100 , pp. 2235-2241
    • Ohgaki, H.1    Kleihues, P.2
  • 310
    • 0030031642 scopus 로고    scopus 로고
    • Prognosis and outcomes of patients with community-acquired pneumonia. A meta-analysis
    • M.J. Fine, M.A. Smith, and C.A. Carson Prognosis and outcomes of patients with community-acquired pneumonia. A meta-analysis Jama 275 1996 134 141
    • (1996) Jama , vol.275 , pp. 134-141
    • Fine, M.J.1    Smith, M.A.2    Carson, C.A.3
  • 311
    • 33847155159 scopus 로고    scopus 로고
    • Infectious diseases society of America/American thoracic society consensus guidelines on the management of community-acquired pneumonia in adults
    • L.A. Mandell, R.G. Wunderink, and A. Anzueto Infectious diseases society of America/American thoracic society consensus guidelines on the management of community-acquired pneumonia in adults Clin Infect Dis 44 2007 S27 S72
    • (2007) Clin Infect Dis , vol.44 , pp. S27-S72
    • Mandell, L.A.1    Wunderink, R.G.2    Anzueto, A.3
  • 312
    • 80053277530 scopus 로고    scopus 로고
    • OCEBM Levels of Evidence Working Group Oxford Centre for Evidence-Based Medicine
    • OCEBM Levels of Evidence Working Group The Oxford 2011 Levels of Evidence 2011 Oxford Centre for Evidence-Based Medicine http://www.cebm.net/index.aspx?o=5653
    • (2011) The Oxford 2011 Levels of Evidence


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