Loss of chromosome 10 is an independent prognostic factor in high-grade gliomas

British Journal of Cancer

Volumn 81, Issue 8, 1999, Pages 1371-1377

  Balesaria, S ^a   Brock, C ^a   Bower, M ^b   Clark, J ^a   Nicholson, S K ^a   Lewis, P ^a   De Sanctis, S ^a   Evans, H ^a   Peterson, D ^a   Mendoza, N ^a   Glaser, M G ^a   Newlands, E S ^a   Fisher, R A ^a  

^a CHARING CROSS HOSPITAL   (United Kingdom)

^b CHELSEA AND WESTMINSTER HOSPITAL   (United Kingdom)

Author keywords

Brain tumour; Glioma; Loss of heterozygosity; Microsatellite

Indexed keywords

MICROSATELLITE DNA;

ADULT; AGED; ALLELE; ARTICLE; CANCER GRADING; CANCER SURVIVAL; CHROMOSOME 10; CHROMOSOME 10P; CHROMOSOME 10Q; CHROMOSOME ANALYSIS; CONTROLLED STUDY; FEMALE; GENE LOCATION; GENOTYPE; GLIOBLASTOMA; GLIOMA; HETEROZYGOSITY LOSS; HUMAN; HUMAN CELL; MAJOR CLINICAL STUDY; MALE; MULTIVARIATE ANALYSIS; ONSET AGE; PRIORITY JOURNAL; PROGNOSIS; SURVIVAL TIME; TUMOR SUPPRESSOR GENE;

EID: 0032731539     PISSN: 00070920     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjc.6693403     Document Type: Article

References (40)

1. Barker FG, Davis RL, Chang SM and Prados MD (1996) Necrosis as a prognostic factor in glioblastoma multiforme. Cancer 77: 1161-1166
2. Bigner SH, Mark J and Bigner DD (1990) Cytogenetics of human brain tumours. Cancer Genet Cytogenet 47: 141-154
3. Bostrom J, Cobbers JMJL, Wolter M, Tabatabai G, Weber RG, Lichter P, Collins VP and Reifenberger G (1998) Mutation of the PTEN (MMAC1) tumor suppressor gene in a subset of glioblastomas but not in meningiomas with loss of chromosome arm 10q. CancerRes 58: 29-33
4. Brada M, Thomas DGT, Bleehen NM, Roberts JT, Senanayake F, Abram P, Lantos PL, Moss TH, Ironside JW, Whaley JB and Stenning SP (1998) Medical Research Council (MRC) randomised trial of adjuvant chemotherapy in high-grade glioma (HGG)-BRO5. Am Soc Clin Oncol 17: 400a
5. Bruner JM (1994) Neuropathology of malignant gliomas. Semin Oncol 21: 126-138
6. Campomenosi P, Ottaggio L, Moro F, Urbini S, Bogliolo M, Zunino A, Camoriano A, Inga A, Gentile SL, Pellegata NS, Bonassi S, Bruzzone E, Iannone R, Pisani R, Menichini P, Ranzani GN, Bonatti S, Abbondandolo A and Fronza G (1996) Study on aneuploidy and p53 mutations in astrocytomas. Cancer Genet Cytogenet 88: 95-102
7. Chang CH, Horton J, Schoenfeld D, Salazer O, Perez-Tamayo R, Kramer S, Weinstein A, Nelson JS and Tsukada Y (1983) Comparison of postoperative radiotherapy and combined postoperative radiotherapy and chemotherapy in the multidisciplinary management of malignant gliomas. A joint Radiation Therapy Oncology Group and Eastern Cooperative Oncology Group study. Cancer 52: 997-1007
8. Chernova OB, Somerville RP and Cowell JK (1998) A novel gene LGH, from 10q24 is rearranged and down-regulated in malignant brain tumors. Oncogene 17: 2873-2881
9. Collins VP (1995) Gene amplification in human gliomas. Glia 15: 289-296
10. Cox D (1972) Regression models and life-tables. J R Stat Soc B 34: 187-220
11. Cunningham JM, Kimmel DW, Scheithauer BW, O'Fallon JR, Novotny PJ and Jenkins RB (1997) Analysis of proliferation markers and p53 expression in gliomas of astrocytic origin: relationships and prognostic value. J Neurosurg 86: 121-130
12. Daumas-Duport C, Scheithauer B, O'Fallon J and Kelly P (1988) Grading of astrocytomas: a simple and reproducible method. Cancer 62: 2152-2165
13. Fisher RA, Paradinas FJ, Soteriou BA, Foskett M and Newlands ES (1997) Diploid hydatidiform moles with fetal red blood cells in molar villi: 2 - Genetics. J Pathology 181: 189-195
14. Fults D, Pedono CA, Thompson GE, Uchiyama CM, Gumpper KL, Iliev D, Vinson VL, Tavtigian SV and Perry WL 3rd (1998) Microsatellite deletion mapping on chromosome 10q and mutation analysis of MMAC1, FAS and MXII in human glioblastoma multiforme. Int J Oncol 12: 905-910
15. Ganju V, Jenkins RB, O'Fallon JR, Scheithauer BW. Ransom DT, Katzmann JA and Kimmel DW (1994) Prognostic factors in gliomas. A multivariate analysis of clinical, pathologic, flow cytometric, cytogenetic, and molecular markers. Cancer 74: 920-927
16. GDB(™) Human Genome Database [database online]. Baltimore (Maryland, USA): Johns Hopkins University, 1990. Available from Internet: URI. http://www.gdb.org
17. Ichimura K, Schmidt EE, Miyakawa A, Goike HM and Collins VP (1998) Distinct patterns of deletion on 10p and 10q suggest involvement of multiple tumor suppressor genes in the development of astrocytic gliomas of different malignancy grades. Genes Chromosomes Cancer 22: 9-15
18. Jen J, Harper JW, Bigner SH, Bigner DD, Papadopoulos N, Markowitz S, Willson JK, Kiozler KW and Vogelstein B (1994) Deletion of p15 and p16 genes in brain tumours. Cancer Res 54: 6353-6358
19. Kaplan E and Meier P (1958) Nonparametric estimation from incomplete observations. J Am Stat Assoc 53: 457-481
20. Kon H, Sonada Y, Kumaba T, Yoshimoto T, Sekiya T and Murakami Y (1998) Structural and functional evidence for the presence of tumor suppressor genes on the short arm of chromosome 10 in human gliomas. Oncogene 16: 257-263
21. Korkolopoulou P, Christodoulou P, Kouzelis K, Hadjiyannakis M, Priftis A, Statnoulis, G, Seretis A and Thomas-Tsagli E (1977) MDM2 and p53 expression in gliomas: a multivariate survival analysis including proliferation markers and epidermal growth factor receptor. Br J Cancer 75: 1269-1278
22. Krouwer HG, Davis RL, Silver P and Prados M (1991) Gemistocytic astrocytomas: a reappraisal. J Neurosurg 74: 399-406
23. Leenstra S, Oskam NT, Buleveld EH, Bosch DA, Troost D and Hulsebos TJM (1998) Genetic subtype of human malignant astrocytoma correlate with survival. Int J Cancer 79: 159-165
24. Li J, Yen C, Liaw D, Podsypanina K, Bose S, Wang SI, Puc J, Miliaresis C, Rodgers L, McCombie R, Bigner SH, Giovanella BC, Ittmann M, Tycko B, Hibshoosh H, Wigler MH and Parsons R (1997) PTEN, a putative protein tyrosine phosphatase gene mutated in human, brain, breast and prostate cancer. Science 275: 1943-1947
25. Lin H, Bondy ML, Landford LA, Hess KR, Delelos GL, Wu X, Chan W, Pershouse MA, Yung WKA and Steck PA (1998) Alleleic deletion analyses of MMAC/PTEN and DMBT1 loci in gliomas: relationship to prognostic significance. Clin Cancer Res 4: 2447-2454
26. Louis DN and Gusella JF (1995) A tiger behind many doors: multiple genetic pathways to malignant glioma. Trends Genet 11: 412-415
27. Mollenhauser J, Wiemann S, Scheurlen W, Korn B, Hayashi Y, Wilgenbus KK, von Diemling A and Poustka A (1997) DBMT1, a new member of the SRCR superfamily, on chromosome 10q25.3-26.1 is deleted in malignant brain tumours. Nature Genet 17: 32-39
28. Newlands ES, O'Reilly SM, Glaser MG, Bower M, Evans H, Brock C, Brampton MH, Colquhoun I, Lewis P, Rice-Edwards JM, Illingworth RD and Richards PG (1996) The Charing Cross Hospital experience with temozolomide in patients with gliomas. Eur J Cancer 32A: 2236-2241
29. Peto R, Pike M, Armitage P, Breslow N, Cox D, Howard S, Mantel N, McPhearson K, Peto J and Smith P (1977) Design and analysis of randomised clinical trials requiring prolonged observation of each patient II: analysis and examples. Br J Cancer 35: 1-39
30. Rainov NG, Dobberstein KU, Bahn H, Holzhausen HJ, Lautenschlager C, Heidecke V and Burkert W (1997) Prognostic factors in malignant glioma: influence of the overexpression of oncogene and tumor-suppressor gene products on survival. J Neurooncol 35: 13-28
31. Rasheed BK, McLendon RE, Friedman HS, Friedman AH, Fuchs HE, Bigner DD and Bigner SH (1995) Chromosome 10 deletion mapping in human gliomas: a common deletion in 10q25. Oncogene 10: 2243-2246
32. Rasheed BKA, Stenzel TT, McLendon RE, Parsons R, Friedman AH, Friedman HS, Bigner DD and Bigner SH (1997) PTEN gene mutations are seen in high-grade but not in low-grade gliomas. Cancer Res 57: 4187-4190
33. Report of the Medical Research Council Brain Tumour Working Party (1990) Prognostic factors for high-grade malignant glioma: development of a prognostic index. J Neurooncol 9: 47-55
34. Steck PA, Pershouse MA, Jasser SA, Yung WKA, Lin H, Ligon AH, Langford LA, Baumgard ML, Hattier T, Davis T, Frye C, Hu R, Swedlund B, Teng DHF and Tavtigian SV (1997) Identification of a candidate tumour suppressor gene MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers. Nature Genet 15: 356-362
35. Voesten AM, Bijleveld EH. Westerveld A and Hulsebos TJ (1997) Fine mapping of a region of common deletion on chromosome arm 10p in human glioma. Genes Chromosomes Cancer 20: 167-172
36. von Deimling A, Louis DN and Wiestler OD (1995) Molecular pathways in the formation of gliomas. Glia 15: 328-338
37. Waha A, Baumann A, Wolf HK, Fimmers R, Neumann J, Kindermann D, Astrahantseff K, Blumeke I, von-Deimling A and Schlegel U (1996) Lack of prognostic relevance of alterations in the epidermal growth factor receptor-transforming growth factor-alpha pathway in human astrocytic gliomas. J Neurosurg 85: 634-641
38. Wright DK and Manos MM (1990) Sample preparation from paraffin-embedded tissues. In: PCR Protocols, a Guide to Methods and Applications, Innis MA,
39. Gelfand DH, Sninsky JJ and White TJ (eds), pp. 153-158. Academic Press: London
40. Zhu A, Shaeffer J, Leslie S, Kolm P and El-Mahdi AM (1996) Epidermal growth factor receptor: an independent predictor of survival in astrocytic tumors given definitive irradiation. Int J Radiation Oncol Biol Phys 34: 809-815