-
1
-
-
4944255253
-
Genetic pathways to glioblastoma: A population-based study
-
Ohgaki H, Dessen P, Jourde, B et al. Genetic pathways to glioblastoma: a population-based study. Cancer Res 2004; 64: 6892-9.
-
(2004)
Cancer Res.
, vol.64
, pp. 6892-6899
-
-
Ohgaki, H.1
Dessen, P.2
Jourde, B.3
-
2
-
-
0032601166
-
Primary and secondary glioblastomas: From concept to clinical diagnosis
-
Kleihues P, Ohgaki H. Primary and secondary glioblastomas: from concept to clinical diagnosis. Neuro-oncology 1999; 1: 44-51.
-
(1999)
Neuro-oncology
, vol.1
, pp. 44-51
-
-
Kleihues, P.1
Ohgaki, H.2
-
4
-
-
0023429079
-
Increased expression of the epidermal growth factor receptor gene in malignant gliomas is invariably associated with gene amplification
-
Wong AJ, Bigner SH, Bigner DD et al. Increased expression of the epidermal growth factor receptor gene in malignant gliomas is invariably associated with gene amplification. Proc Natl Acad Sci USA 1987; 84: 6899-903.
-
(1987)
Proc. Natl. Acad. Sci. USA
, vol.84
, pp. 6899-6903
-
-
Wong, A.J.1
Bigner, S.H.2
Bigner, D.D.3
-
5
-
-
0026793260
-
Amplification and/or over-expression of platelet-derived growth factor receptors and epidermal growth factor receptor in human glial tumors
-
Fleming TP, Sexena A, Clark WC et al. Amplification and/or over-expression of platelet-derived growth factor receptors and epidermal growth factor receptor in human glial tumors. Cancer Res 1992; 52: 4550-3.
-
(1992)
Cancer Res.
, vol.52
, pp. 4550-4553
-
-
Fleming, T.P.1
Sexena, A.2
Clark, W.C.3
-
6
-
-
0029800810
-
Refined mapping of 12q13-q15 amplicons in human malignant gliomas suggests CDK4/SAS and MDM2 as independent amplification targets
-
Reifenberger G, Ichimura K, Reifenberger J et al. Refined mapping of 12q13-q15 amplicons in human malignant gliomas suggests CDK4/SAS and MDM2 as independent amplification targets. Cancer Res 1996; 56: 5141-5.
-
(1996)
Cancer Res.
, vol.56
, pp. 5141-5145
-
-
Reifenberger, G.1
Ichimura, K.2
Reifenberger, J.3
-
7
-
-
0034649787
-
Deregulation of the p14ARF/MDM2/p53 pathway is a prerequisite for human astrocytic gliomas with G1-S transition control gene abnormalities
-
Ichimura K, Bolin MB, Goike HM et al. Deregulation of the p14ARF/MDM2/p53 pathway is a prerequisite for human astrocytic gliomas with G1-S transition control gene abnormalities. Cancer Res 2000; 60: 417-24.
-
(2000)
Cancer Res.
, vol.60
, pp. 417-424
-
-
Ichimura, K.1
Bolin, M.B.2
Goike, H.M.3
-
8
-
-
0035133842
-
Promoter hypermethylation of the RB1 gene in glioblastomas
-
Nakamura M, Yonekawa Y, Kleihues P et al. Promoter hypermethylation of the RB1 gene in glioblastomas. Lab Invest 2001; 81: 77-82.
-
(2001)
Lab. Invest.
, vol.81
, pp. 77-82
-
-
Nakamura, M.1
Yonekawa, Y.2
Kleihues, P.3
-
9
-
-
17144436629
-
Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers
-
Steck PA, Pershouse MA, Jasser SA et al. Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers. Nat Genet 1997; 15: 356-62.
-
(1997)
Nat. Genet.
, vol.15
, pp. 356-362
-
-
Steck, P.A.1
Pershouse, M.A.2
Jasser, S.A.3
-
10
-
-
0030799909
-
Somatic mutations of PTEN in glioblastoma multiforme
-
Wang SI, Puc J, Li J et al. Somatic mutations of PTEN in glioblastoma multiforme. Cancer Res 1997; 57: 4183-6.
-
(1997)
Cancer Res.
, vol.57
, pp. 4183-4186
-
-
Wang, S.I.1
Puc, J.2
Li, J.3
-
11
-
-
0035880788
-
PTEN mutation, EGFR amplification, and outcome in patients with anaplastic astrocytoma and glioblastoma multiforme
-
Smith JS, Tachibana I, Passe SM et al. PTEN mutation, EGFR amplification, and outcome in patients with anaplastic astrocytoma and glioblastoma multiforme. J Natl Cancer Inst 2001; 93: 1246-56.
-
(2001)
J. Natl. Cancer Inst.
, vol.93
, pp. 1246-1256
-
-
Smith, J.S.1
Tachibana, I.2
Passe, S.M.3
-
12
-
-
4143096081
-
Comparative genomic hybridization (CGH)-arrays pave the way for identification of novel cancer-related genes
-
Inazawa J, Inoue J, Imoto I. Comparative genomic hybridization (CGH)-arrays pave the way for identification of novel cancer-related genes. Cancer Sci 2004; 95: 559-63.
-
(2004)
Cancer Sci.
, vol.95
, pp. 559-563
-
-
Inazawa, J.1
Inoue, J.2
Imoto, I.3
-
13
-
-
2542622017
-
Frequent silencing of low density lipoprotein receptor-related protein 1B (LRP1B) expression by genetic and epigenetic mechanisms in esophageal squamous-cell carcinoma
-
Sonoda I, Imoto I, Inoue J et al. Frequent silencing of low density lipoprotein receptor-related protein 1B (LRP1B) expression by genetic and epigenetic mechanisms in esophageal squamous-cell carcinoma. Cancer Res 2004; 64: 3741-7.
-
(2004)
Cancer Res.
, vol.64
, pp. 3741-3747
-
-
Sonoda, I.1
Imoto, I.2
Inoue, J.3
-
14
-
-
15844425850
-
Screening of DNA copy-number aberrations in gastric cancer cell lines by array-based comparative genomic hybridization
-
Takada H, Imoto I, Tsuda H et al. Screening of DNA copy-number aberrations in gastric cancer cell lines by array-based comparative genomic hybridization. Cancer Sci 2005; 96: 100-10.
-
(2005)
Cancer Sci.
, vol.96
, pp. 100-110
-
-
Takada, H.1
Imoto, I.2
Tsuda, H.3
-
15
-
-
17744373486
-
Frequent silencing of DBC1 is by genetic or epigenetic mechanisms in non-small cell lung cancers
-
Izumi H, Inoue J, Yokoi S et al. Frequent silencing of DBC1 is by genetic or epigenetic mechanisms in non-small cell lung cancers. Hum Mol Genet 2005; 14: 997-1007.
-
(2005)
Hum. Mol. Genet.
, vol.14
, pp. 997-1007
-
-
Izumi, H.1
Inoue, J.2
Yokoi, S.3
-
16
-
-
0345268776
-
Grade II astrocytomas are subgrouped by chromosome aberrations
-
Hirose Y, Aldape KD, Chang S et al. Grade II astrocytomas are subgrouped by chromosome aberrations. Cancer Genet Cytogenet 2003; 142: 1-7.
-
(2003)
Cancer Genet. Cytogenet.
, vol.142
, pp. 1-7
-
-
Hirose, Y.1
Aldape, K.D.2
Chang, S.3
-
17
-
-
2342468007
-
Application of bacterial artificial chromosome array-based comparative genomic hybridization and spectral karyotyping to the analysis of glioblastoma multiforme
-
Cowell JK, Matsui S, Wang YD et al. Application of bacterial artificial chromosome array-based comparative genomic hybridization and spectral karyotyping to the analysis of glioblastoma multiforme. Cancer Genet Cytogenet 2004; 151: 36-51.
-
(2004)
Cancer Genet. Cytogenet.
, vol.151
, pp. 36-51
-
-
Cowell, J.K.1
Matsui, S.2
Wang, Y.D.3
-
18
-
-
0036309975
-
A novel target gene, SKP2, within the 5p13 amplicon that is frequently detected in small cell lung cancers
-
Yokoi S, Yasui K, Saito-Ohara F et al. A novel target gene, SKP2, within the 5p13 amplicon that is frequently detected in small cell lung cancers. Am J Pathol 2002; 161: 207-16.
-
(2002)
Am. J. Pathol.
, vol.161
, pp. 207-216
-
-
Yokoi, S.1
Yasui, K.2
Saito-Ohara, F.3
-
19
-
-
3042692332
-
Amplification and overexpression of SKP2 are associated with metastasis of non-small-cell lung cancers to lymph nodes
-
Yokoi S, Yasui K, Mori M et al. Amplification and overexpression of SKP2 are associated with metastasis of non-small-cell lung cancers to lymph nodes. Am J Pathol 2004; 165: 175-80.
-
(2004)
Am. J. Pathol.
, vol.165
, pp. 175-180
-
-
Yokoi, S.1
Yasui, K.2
Mori, M.3
-
20
-
-
11844306647
-
Skp2 overexpression is a p27Kip1-independent predictor of poor prognosis in patients with biliary tract cancers
-
Sanada T, Yokoi S, Arii S et al. Skp2 overexpression is a p27Kip1-independent predictor of poor prognosis in patients with biliary tract cancers. Cancer Sci 2004; 95: 969-76.
-
(2004)
Cancer Sci.
, vol.95
, pp. 969-976
-
-
Sanada, T.1
Yokoi, S.2
Arii, S.3
-
21
-
-
0031609609
-
Identification of amplified DNA sequences on double minute chromosomes in a leukemic cell line KY821 by means of spectral karyotyping and comparative genomic hybridization
-
Ariyama Y, Sakabe T, Shinomiya T et al. Identification of amplified DNA sequences on double minute chromosomes in a leukemic cell line KY821 by means of spectral karyotyping and comparative genomic hybridization. J Hum Genet 1998; 43: 187-90.
-
(1998)
J. Hum. Genet.
, vol.43
, pp. 187-190
-
-
Ariyama, Y.1
Sakabe, T.2
Shinomiya, T.3
-
22
-
-
0035884398
-
Identification of cIAP1 as a candidate target gene within an amplicon at 11q22 in esophageal squamous cell carcinomas
-
Imoto I, Yang ZQ, Pimkhaokham A et al. Identification of cIAP1 as a candidate target gene within an amplicon at 11q22 in esophageal squamous cell carcinomas. Cancer Res 2001; 61: 6629-34.
-
(2001)
Cancer Res.
, vol.61
, pp. 6629-6634
-
-
Imoto, I.1
Yang, Z.Q.2
Pimkhaokham, A.3
-
23
-
-
0036073357
-
Comparative genomic hybridization in glioma: A meta-analysis of 509 cases
-
Koschny R, Koschny T, Froster UG et al. Comparative genomic hybridization in glioma: a meta-analysis of 509 cases. Cancer Genet Cytogenet 2002; 135: 147-59.
-
(2002)
Cancer Genet. Cytogenet.
, vol.135
, pp. 147-159
-
-
Koschny, R.1
Koschny, T.2
Froster, U.G.3
-
24
-
-
3142759350
-
Genetic analysis of human glioblastomas using a genomic microarray system
-
Suzuki T, Maruno M, Wada K et al. Genetic analysis of human glioblastomas using a genomic microarray system. Brain Tumor Pathol 2004; 21: 27-34.
-
(2004)
Brain Tumor Pathol.
, vol.21
, pp. 27-34
-
-
Suzuki, T.1
Maruno, M.2
Wada, K.3
-
25
-
-
0031895154
-
DNA copy number amplifications in human neoplasms: Review of comparative genomic hybridization studies
-
Knuutila S, Bjorkqvist AM, Autio, K et al. DNA copy number amplifications in human neoplasms: review of comparative genomic hybridization studies. Am J Pathol 1998; 152: 1107-23.
-
(1998)
Am. J. Pathol.
, vol.152
, pp. 1107-1123
-
-
Knuutila, S.1
Bjorkqvist, A.M.2
Autio, K.3
-
27
-
-
0035476237
-
High expression of S-phase kinase-interacting protein 2, human F-box protein, correlates with poor prognosis in oral squamous cell carcinomas
-
Kudo Y, Kitajima S, Sato S et al. High expression of S-phase kinase-interacting protein 2, human F-box protein, correlates with poor prognosis in oral squamous cell carcinomas. Cancer Res 2001; 61: 7044-7.
-
(2001)
Cancer Res.
, vol.61
, pp. 7044-7047
-
-
Kudo, Y.1
Kitajima, S.2
Sato, S.3
-
28
-
-
0036645405
-
Clinical and biological significance of S-phase kinase-associated protein 2 (Skp2) gene expression in gastric carcinoma: Modulation of malignant phenotype by Skp2 overexpression, possibly via p27 proteolysis
-
Masuda TA, Inoue H, Sonoda H et al. Clinical and biological significance of S-phase kinase-associated protein 2 (Skp2) gene expression in gastric carcinoma: modulation of malignant phenotype by Skp2 overexpression, possibly via p27 proteolysis. Cancer Res 2002; 62: 3819-25.
-
(2002)
Cancer Res.
, vol.62
, pp. 3819-3825
-
-
Masuda, T.A.1
Inoue, H.2
Sonoda, H.3
-
29
-
-
0036102867
-
S-phase kinase-associated protein 2 expression in non-Hodgkin's lymphoma inversely correlates with p27 expression and defines cells in S phase
-
Chiarle R, Fan Y, Piva R et al. S-phase kinase-associated protein 2 expression in non-Hodgkin's lymphoma inversely correlates with p27 expression and defines cells in S phase. Am J Pathol 2002; 160: 1457-66.
-
(2002)
Am. J. Pathol.
, vol.160
, pp. 1457-1466
-
-
Chiarle, R.1
Fan, Y.2
Piva, R.3
-
30
-
-
0032713810
-
Decreased p27 (Kip1) expression and cyclin D1 overexpression, alone and in combination, influence recurrence and survival of patients with resectable extrahepatic bile duct carcinoma
-
Hui AM, Cui X, Makuuchi M et al. Decreased p27 (Kip1) expression and cyclin D1 overexpression, alone and in combination, influence recurrence and survival of patients with resectable extrahepatic bile duct carcinoma. Hepatology 1999; 30: 1167-73.
-
(1999)
Hepatology
, vol.30
, pp. 1167-1173
-
-
Hui, A.M.1
Cui, X.2
Makuuchi, M.3
-
31
-
-
17544366706
-
p27(Kip1) expression in normal epithelia, precancerous lesions, and carcinomas of the gallbladder: Association with cancer progression and prognosis
-
Hui AM, Li X, Shi YZ et al. p27(Kip1) expression in normal epithelia, precancerous lesions, and carcinomas of the gallbladder: association with cancer progression and prognosis. Hepatology 2000; 31: 1068-72.
-
(2000)
Hepatology
, vol.31
, pp. 1068-1072
-
-
Hui, A.M.1
Li, X.2
Shi, Y.Z.3
-
32
-
-
0034675922
-
The F-box protein Skp2 is a ubiquitylation target of a Cul1-based core ubiquitin ligase complex: Evidence for a role of Cul1 in the suppression of Skp2 expression in quiescent fibroblasts
-
Wirbelauer C, Sutterluty H, Blondel M et al. The F-box protein Skp2 is a ubiquitylation target of a Cul1-based core ubiquitin ligase complex: evidence for a role of Cul1 in the suppression of Skp2 expression in quiescent fibroblasts. EMBO J 2000; 19: 5362-75.
-
(2000)
EMBO J.
, vol.19
, pp. 5362-5375
-
-
Wirbelauer, C.1
Sutterluty, H.2
Blondel, M.3
-
33
-
-
0041633899
-
Cell cycle-dependent regulation of the Skp2 promoter by GA-binding protein
-
Imaki H, Nakayama K, Delehouzee S et al. Cell cycle-dependent regulation of the Skp2 promoter by GA-binding protein. Cancer Res 2003; 63: 4607-13.
-
(2003)
Cancer Res.
, vol.63
, pp. 4607-4613
-
-
Imaki, H.1
Nakayama, K.2
Delehouzee, S.3
-
34
-
-
0037989911
-
Skp2 overexpression is a prognostic factor in patients with ovarian adenocarcinoma
-
Shigemasa K, Gu L, O'Brien TJ et al. Skp2 overexpression is a prognostic factor in patients with ovarian adenocarcinoma. Clin Cancer Res 2003; 9: 1756-63.
-
(2003)
Clin. Cancer Res.
, vol.9
, pp. 1756-1763
-
-
Shigemasa, K.1
Gu, L.2
O'Brien, T.J.3
-
35
-
-
0035916325
-
PTEN regulates the ubiquitin-dependent degradation of the CDK inhibitor p27 (KIP1) through the ubiquitin E3 ligase SCF (SKP2)
-
Mamillapalli R, Gavrilova N, Mihaylova VT et al. PTEN regulates the ubiquitin-dependent degradation of the CDK inhibitor p27 (KIP1) through the ubiquitin E3 ligase SCF (SKP2). Curr Biol 2001; 11: 263-7.
-
(2001)
Curr. Biol.
, vol.11
, pp. 263-267
-
-
Mamillapalli, R.1
Gavrilova, N.2
Mihaylova, V.T.3
-
36
-
-
0033398991
-
Analysis of oncogene and tumor suppressor gene alterations in pediatric malignant astrocytomas reveals reduced survival for patients with PTEN mutations
-
Raffel C, Frederick L, O'Fallon JR et al. Analysis of oncogene and tumor suppressor gene alterations in pediatric malignant astrocytomas reveals reduced survival for patients with PTEN mutations. Clin Cancer Res 1999; 5: 4085-90.
-
(1999)
Clin. Cancer Res.
, vol.5
, pp. 4085-4090
-
-
Raffel, C.1
Frederick, L.2
O'Fallon, J.R.3
-
37
-
-
17144452027
-
Short postoperative survival for glioblastoma patients with a dysfunctional Rb1 pathway in combination with no wild-type PTEN
-
Backlund LM, Nilsson BR, Goike HM et al. Short postoperative survival for glioblastoma patients with a dysfunctional Rb1 pathway in combination with no wild-type PTEN. Clin Cancer Res 2003; 9: 4151-8.
-
(2003)
Clin. Cancer Res.
, vol.9
, pp. 4151-4158
-
-
Backlund, L.M.1
Nilsson, B.R.2
Goike, H.M.3
-
38
-
-
18744373874
-
Downregulation of Skp2 and p27/Kip1 synergistically induces apoptosis in T98G glioblastoma cells
-
Lee SH, McCormick F. Downregulation of Skp2 and p27/Kip1 synergistically induces apoptosis in T98G glioblastoma cells. J Mol Med 2005; 83: 296-307.
-
(2005)
J. Mol. Med.
, vol.83
, pp. 296-307
-
-
Lee, S.H.1
McCormick, F.2
-
39
-
-
0038649638
-
The proteasome: An emerging therapeutic target in cancer
-
Mitchell BS. The proteasome: an emerging therapeutic target in cancer. N Engl J Med 2003; 348: 2597-8.
-
(2003)
N. Engl. J. Med.
, vol.348
, pp. 2597-2598
-
-
Mitchell, B.S.1
|