Alternative lengthening of telomeres and survival in patients with glioblastoma multiforme

Lancet

Volumn 361, Issue 9360, 2003, Pages 836-838

  Hakin Smith, V ^a   Jellinek, D A ^b   Levy, D ^c   Carroll, T ^b   Teo, M ^a   Timperley, W R ^b   McKay, M J ^d   Reddel, R R ^e   Royds, J A ^a,f  

^a UNIVERSITY OF SHEFFIELD   (United Kingdom)

^b ROYAL HALLAMSHIRE HOSPITAL   (United Kingdom)

^c WESTON PARK HOSPITAL   (United Kingdom)

^d PETER MACCALLUM CANCER CENTRE   (Australia)

^e CHILDREN'S MEDICAL RESEARCH INSTITUTE   (Australia)

^f UNIVERSITY OF OTAGO   (New Zealand)

Author keywords

[No Author keywords available]

Indexed keywords

TELOMERASE;

ADULT; AGE; AGED; ARTICLE; CANCER PATIENT; CANCER SURVIVAL; CONTROLLED STUDY; ENZYME ACTIVITY; GLIOBLASTOMA; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; OUTCOMES RESEARCH; PHENOTYPE; PRIORITY JOURNAL; PROGNOSIS; REGRESSION ANALYSIS; TELOMERE;

EID: 0037426088     PISSN: 01406736     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0140-6736(03)12681-5     Document Type: Article

References (5)

1. Latif A.Z.B., Signorini D., Gregor A., Grant R., Ironside J.W., Whittle I.R. Application of the MRC brain tumour prognostic index to patients with malignant glioma not managed in randomised control trial. J Neurol Neurosurg Psychiatry. 64:1998;747-750.
2. Bryan T.M., Englezou A., Dalla-Pozza L., Dunham M.A., Reddel R.R. Evidence for an alternative mechanism for maintaining telomere length in human tumors and tumor-derived cell lines. Nat Med. 3:1997;1271-1274.
3. Bryant J.E., Hutchings K.G., Moyzis R.K., Griffith J.K. Measurement of telomeric DNA content in human tissues. Biotechniques. 23:1997;476-478.
4. Carroll T., Maltby E., Brock I., Royds J., Timperley W.R., Jellinek D. Meningiomas, dicentric chromosomes, gliomas and telomerase activity. J Pathol. 188:1999;395-399.
5. Stewart S.A., Hahn W.C., O'Connor B.F., et al. Telomerase contributes to tumorigenesis by a telomere length-independent mechanism. Proc Natl Acad Sci USA. 99:2002;12606-12611.