Genetically distinct and clinically relevant subtypes of glioblastoma defined by array-based comparative genomic hybridization (array-CGH)

Acta Neuropathologica

Volumn 111, Issue 5, 2006, Pages 465-474

  Korshunov, Andrey ^a   Sycheva, Regina ^a   Golanov, Andrey ^a  

^a BURDENKO NEUROSURGICAL INSTITUTE   (Russian Federation)

Author keywords

Glioblastoma; Microarrays; Molecular genetics; Prognosis

Indexed keywords

DNA; NITROSOUREA; TEMOZOLOMIDE;

ADULT; AGED; ARTICLE; CANCER MORTALITY; CANCER RISK; CANCER SURVIVAL; CLUSTER ANALYSIS; COMPARATIVE GENOMIC HYBRIDIZATION; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; CORRELATION ANALYSIS; FEMALE; FLUORESCENCE IN SITU HYBRIDIZATION; GENE AMPLIFICATION; GENE NUMBER; GENETIC ANALYSIS; GENETIC RISK; GLIOBLASTOMA; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; KAPLAN MEIER METHOD; MAJOR CLINICAL STUDY; MALE; MOLECULAR CLONING; NEUROIMAGING; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; PROGNOSIS; RISK ASSESSMENT; RISK FACTOR; STATISTICAL ANALYSIS; STATISTICAL SIGNIFICANCE; SURVIVAL RATE;

ADULT; AGED; ALLELIC IMBALANCE; CLUSTER ANALYSIS; DNA, NEOPLASM; FEMALE; GENE DOSAGE; GLIOBLASTOMA; HUMANS; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; NUCLEIC ACID HYBRIDIZATION; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PROGNOSIS; SUPRATENTORIAL NEOPLASMS;

EID: 33646230037     PISSN: 00016322     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00401-006-0057-9     Document Type: Article

References (45)

1. Akimoto S, Nakanishi Y, Sakamoto M, Kanai Y, Hirohashi S (2004) Laminin 5 beta and gamma 2 chains are frequently co-expressed in cancer cells. Pathol Int 54:688-692
2. Arslantas A, Artan S, Oner U, Muslumanoglu H, Durmaz R, Cosan E, Atasoy MA, Basaran N, Tel E (2004) The importance of genomic copy number changes in the prognosis of glioblastoma multiforme. Neurosurg Rev 27:58-64
3. Baron V, Adamson ED, Calogero A, Ragona G, Mercola D (2005) The transcriptional factor EGR1 is a direct regulator of multiple tumor suppressors including TGFbeta1, PTEN, p53 and fibronectin. Cancer Gene Ther 13:115-124
4. Bassi DE, Fu J, Lopez de Cicco R Klein-Szanto AJ (2005) Proprotein convertases: "Master switches" in the regulation of tumor growth and progression. Mol Carcinogen 44:151-161
5. Bredel M, Bredel C, Juric D, Harsh GR, Vogel H, Recht LD, Sikic BI (2005) High-resolution genome-wide mapping of genetic alterations in human glial brain tumors. Cancer Res 65:4088-4096
6. Burton E, Lamborn KR, Feuerstein BG, Prados M, Scott J, Forsyth P, Passe S, Jenkins RB, Aldape KD (2002) Genetic aberrations defined by comparative genome hybridization distinguish long-term from typical survivors in glioblastoma. Cancer Res 62:6205-6210
7. Bussey KJ, Lawce HJ, Himoe E, Shu XO, Heerema NA, Perlman EJ, Olson SB, Magenis RE (2001) SNRPN methylation patterns in the germ cell tumors as a reflection of primordial germ cell development. Genes Chromosome Cancer 32:342-352
8. Callucci M, Merola R, Farsetti A, Orlandi G, Sentinelli S, De Carli P, Leonardo C, Carlini P, Guadangi F, Sperduti I, Cianciulli AM (2005) Cytogenetic profile as an additional marker to pathological features in clinically localized prostate carcinoma. Cancer Lett (in press)
9. Coleman WB, Tsongalis GJ (2002) The molecular basis of human cancer. Humana Press, Totowa, 588 pp
10. Cowell JK, Matsui S, Wang YD, LaDuca J, Conroy J, McQuad D, Nowak NJ (2004) Application of bacterial artificial chromosome array-based comparative genomic hybridization and spectral karyotyping to the analysis of glioblastoma multiforme. Cancer Genet Cytogenet 151:36-51
11. Grifoni D, Garoia F, Schimanski CC, Smitz G, Laureneti E, Galle PR, Pession A, Cavicci S, Strand D (2004) The human protein Hugl-1 substitutes for Drosophila lethal giant larvae tumor suppressor function in vivo. Oncogene 23:8688-8694
12. Grossman SA, Batara JF (2004) Current management of glioblastoma multiforme. Semin Oncol 31:635-644
13. Hibi K, Trink B, Patturajan M, Westra WH, Caballero OI, Hill DE, Ratovitski EA, Jen J, Sidransky D (2000) AIS is an oncogene amplified in squamous cell carcinoma. Proc Nat Acad Sci USA 97:5462-5477
14. Hidalgo A, Baudis M, Pedersen I, Arreola H, Pina P, Vazquez-Ortiz G, Hernandez D, Gonzalez D, Lazos M, Lopez R, Perez C, Carcia J (2005) Microarray comparative genomic hybridization detection of chromosomal imbalances in uterine cervix carcinoma. BMC Cancer 5:77
15. Holland EC (2000) Glioblastoma multiforme: The terminator. Proc Nat Acad Sci USA 97:6242-6244
16. Hu Y, Liu Y, Pelletier S, Buchdunger E, Warmuth M, Fabbro D, Hallek M, Van Etten RA, Li S (2004) Requirement of Src kinases Lyn, Hck, and Fgr for BCR-ABL1-induced B-lymphoblastic leukemia but not chronic myeloid leukemia. Nat Genet 36:453-461
17. Huhn SL, Mohapatra G, Bollen A, Lamborn K, Prados MD, Feuerstein BG (1999) Chromosomal abnormalities in glioblastoma multiforme by comparative genomic hybridization: Correlation with radiation treatment outcome. Clin Cancer Res 5:1435-1433
18. Ichimura K, Ohgaki H, Kleihues P, Collins VP (2004) Molecular pathogenesis of astrocytic tumors. J Neurooncol 70:137-160
19. Kleihues P, Cavenee WK (2000) Tumors of the nervous system. Pathology and genetics: World Health Organization international classification of tumours. WHO/IARC, Lyon, France
20. Korshunov A, Golanov A, Sycheva R, Pronin I (1999) Prognostic value of tumour-associated antigens immunoreactivity and apoptosis in cerebral glioblastomas: An analysis of 168 cases. J Clin Pathol 52:574-580
21. Korshunov A, Sycheva R, Golanov A (2004) Molecular stratification of diagnostically challenging high-grade gliomas composed of small cells. The utility of fluorescence in situ hybridization. Clin Cancer Res 10:7820-7826
22. Koschny R, Koschny T, Froster UG, Krupp W, Zuber MA (2002) Comparative genomic hybridization in glioma: A meta-analysis of 509 cases. Cancer Genet Cytogenet 135:147-159
23. Lamborn KR, Chang SM, Prados MD (2004) Prognostic factors for survival of patients with glioblastoma. Recursive portioning analysis. Neuro-oncology 6:227-235
24. Lutterbach J, Saurbrei W, Guttenberg R (2003) Multivariate analysis of prognostic factors in patients with glioblastomas. Strahlenther Onkol 179:8-15
25. Misra A, Pellarin M, Nigro J, Smirnov I, Moore D, Lamborn KR, Pinkel D, Albertson DG, Feuerstein BG (2005) Array comparative genomic hybridization identifies genetic subgroups in grade 4 human astrocytoma. Clin Cancer Res 11:2907-2918
26. Melino G, De LV, Vousden KH (2002) P73: Friend or foe in tumorigenesis. Nat Rev Cancer 2:605-615
27. Mohapatra G, Bollen AW, Kim DH, Lamborn K, Moore DH, Prados MD, Feuerstein BG (1998) Genetic analysis of glioblastoma multiforme provides evidence for subgroups within the grade. Genes Chromosome Cancer 21:195-206
28. Nakahara Y, Shiraishi T, Okamoto H, Mineta T, Oishi T, Sasaki T, Tabuchi K (2004) Detrended fluctuation analysis of genome-wide copy number profiles of glioblastomas using array-based comparative genomic hybridization. Neuro-Oncology 6:281-289
29. Nigro J, Misra A, Zhang L, Smirnov I, Colman H, Griffin C, Ozburn N, Chen M, Pan E, Koul P, Yung WKA, Feuerstein BG, Aldape KD (2005) Integrated array-comparative genomic hybridization and expression array profiles identify clinically relevant subtypes of glioblastoma. Cancer Res 65:1678-1686
30. Parrella P, Scintu M, Prencipe M, Poeta ML, Gallo AP, Rabitti C, Rinaldi M, Tommasi S, Paradiso A, Schittulli F, Vallori MF, Toma S, Altomare V, Fazio VM (2005) HIC1 promoter methylation and 17p13.3 allelic loss in invasive ductal carcinoma of the breast. Cancer Lett 222:75-81
31. Purow BW, Haque RM, Noel MW, Su Q, Budrick MJ, Lee J, Sundaresan T, Pastorini S, Park JK, Mikolaenko I, Maric D, Eberhart CG, Fine HA (2005) Expression of Notch-1 and its ligands, Delta-like-1 and jagged-1, is critical for glioma cell survival and proliferation. Cancer Res 65:2353-2363
32. Roerig P, Nessling M, Radlwimmer B, Joos S, Wrobel G, Schwanen C, Reifenberger G, Lichter P (2005) Molecular classification of human gliomas using matrix-based comparative genomic hybridization. Int J Cancer 117:95-103
33. Roussel MF, Sherr CG (2003) Oncogenic potential of the c-FMS protooncogene (CSF-1 receptor). Cell Cycle 2:5-6
34. Sasaki T, Arai H, Beppu T, Ogasawara K (2003) Detection of gene amplification and deletion in high-grade gliomas using a genome DNA microarray (GenoSensor Array 300). Brain Tumor Pathol 20:59-63
35. Schmidt MC, Antweiler S, Urban N, Mueller W, Kuklik A, Meyer-Puttlitz B, Wiestler OD, Louis DN, Fimmers R, von Deimling A (2002) Impact of genotype and morphology on the prognosis of glioblastoma. J Neuropathol Exp Neurol 61:321-328
36. Sloane BF, Yan S, Podgorsky I, Linebaugh BE, Cher ML, Mai J, Cavallo-Medved D, Sameni M, Dosescu J, Moin K (2005) Cathepsin B and tumor proteolysis: Contribution of tumor microenvironment. Semin Cancer Biol 15:149-157
37. Smith JS, Tachibana I, Pohl U, Lee HK, Thanarajasingam U, Portier BP, Ueki K, Ramaswamy S, Billings SJ, Mohrenweiser HW, Louis DN, Jenkins RB (2000) A transcript map of of the chromosome 19q-arm glioma tumor suppressor region. Genomics 64:44-50
38. Snidjers AM, Pinkel D, Albertson DG (2003) Current status and future prospects of array-based comparative genomic hybridization. Brief Funct Genomic Proteomic 2:37-45
39. Strefford JC, Stasevich I, Lane TM, Lu YJ, Oliver T, Young BD (2005) A combination of molecular cytogenetic analyses reveals complex genetic alterations in conventional renal-cell carcinoma. Cancer Genet Cytogenet 159:1-9
40. Suzuki T, Maruno M, Wada K, Kagawa N, Fujimoto Y, Hashimoto N, Izumoto S, Yoshimine T (2004) Genetic analysis of human glioblastoma using a genomic microarray system. Brain Tumor Pathol 21:27-34
41. Thorburn A (2004) Death receptor-induced cell killing. Cell Signal 16:139-144
42. Unoki M, Nakamura U (2001) Growth suppressive effects of BZOP and EGR2, two genes involving in the PTEN signaling pathway. Oncogene 20:4457-4465
43. Wiltshire RN, Herndon JE, Lloyd A, Friedman HS, Bigner DD, Bigner SH, McLendon RE (2004) Comparative genomic hybridization analysis of astrocytomas. Prognostic and diagnostic implications. J Mol Diagn 6:166-179
44. Xing X, Du X, Lu Z, Ning T, Su X, Ke Y (2005) Characterization of the promoter 1A6/DRIM, a novel cancer-related gene, and identification of its transcriptional activator. Gene 344:161-169
45. Yokota J, Tsunetsugu-Yokota Y, Battifora H (1986) Alterations of myc, myb, and ras-Ha proto-oncogenes in cancers are frequent and show clinical correlation. Science 231:261-265