-
1
-
-
0033079597
-
Oncogenic alterations of metabolism
-
Dang C.V., and Semenza G.L. Oncogenic alterations of metabolism. Trends Biochem Sci 24 (1999) 68-72
-
(1999)
Trends Biochem Sci
, vol.24
, pp. 68-72
-
-
Dang, C.V.1
Semenza, G.L.2
-
2
-
-
0030614893
-
2 gradients in solid tumors in vivo: high-resolution measurements reveal a lack of correlation
-
2 gradients in solid tumors in vivo: high-resolution measurements reveal a lack of correlation. Nat Med 3 (1997) 177-182
-
(1997)
Nat Med
, vol.3
, pp. 177-182
-
-
Helmlinger, G.1
Yuan, F.2
Dellian, M.3
Jain, R.K.4
-
3
-
-
0141554617
-
Oxygen and tumour angiogenesis
-
Rubanyi G.M. (Ed), Marcel Dekker Inc, New York
-
Dor Y., and Keshet E. Oxygen and tumour angiogenesis. In: Rubanyi G.M. (Ed). Angiogenesis in health and disease (2000), Marcel Dekker Inc, New York 245-260
-
(2000)
Angiogenesis in health and disease
, pp. 245-260
-
-
Dor, Y.1
Keshet, E.2
-
4
-
-
0031823016
-
The molecular basis of the hypoxia response pathway: tumour hypoxia as a therapy target
-
Blancher C., and Harris A.L. The molecular basis of the hypoxia response pathway: tumour hypoxia as a therapy target. Cancer Metastasis Rev 17 (1998) 187-194
-
(1998)
Cancer Metastasis Rev
, vol.17
, pp. 187-194
-
-
Blancher, C.1
Harris, A.L.2
-
5
-
-
0034037286
-
Microenvironment-induced cancer metastasis
-
Rafstad E.K. Microenvironment-induced cancer metastasis. Int J Radiat Biol 76 (2000) 589-605
-
(2000)
Int J Radiat Biol
, vol.76
, pp. 589-605
-
-
Rafstad, E.K.1
-
6
-
-
0033233243
-
2 homeostasis by hypoxia-inducible factor 1
-
2 homeostasis by hypoxia-inducible factor 1. Annu Rev Cell Dev Biol 15 (1999) 551-578
-
(1999)
Annu Rev Cell Dev Biol
, vol.15
, pp. 551-578
-
-
Semenza, G.L.1
-
7
-
-
0029103274
-
Hypoxia regulates vascular endothelial growth factor gene expression in endothelial cells: identification of a 5′ enhancer
-
Liu Y., Cox S.R., Morita T., and Kourembanas S. Hypoxia regulates vascular endothelial growth factor gene expression in endothelial cells: identification of a 5′ enhancer. Circ Res 77 (1995) 638-643
-
(1995)
Circ Res
, vol.77
, pp. 638-643
-
-
Liu, Y.1
Cox, S.R.2
Morita, T.3
Kourembanas, S.4
-
8
-
-
0142219359
-
Pathobiology, prognosis and targeted therapy for renal cell carcinoma: exploiting the hypoxia-induced pathway
-
Pantuck A.J., Zeng G., Belldegrun A.S., and Figlin R.A. Pathobiology, prognosis and targeted therapy for renal cell carcinoma: exploiting the hypoxia-induced pathway. Clin Cancer Res 9 (2003) 4641-4652
-
(2003)
Clin Cancer Res
, vol.9
, pp. 4641-4652
-
-
Pantuck, A.J.1
Zeng, G.2
Belldegrun, A.S.3
Figlin, R.A.4
-
9
-
-
0030849266
-
Structure and mechanism of carbonic anhydrase
-
Lindskog S. Structure and mechanism of carbonic anhydrase. Pharmacol Ther 74 (1997) 1-20
-
(1997)
Pharmacol Ther
, vol.74
, pp. 1-20
-
-
Lindskog, S.1
-
10
-
-
0031748828
-
The contribution of lactic acid to acidification of tumours: studies of variant cells lacking lactate dehydrogenase
-
Yamagata M., Hasuda K., Stamato T., and Tannock I.F. The contribution of lactic acid to acidification of tumours: studies of variant cells lacking lactate dehydrogenase. Br J Cancer 77 (1998) 1726-1731
-
(1998)
Br J Cancer
, vol.77
, pp. 1726-1731
-
-
Yamagata, M.1
Hasuda, K.2
Stamato, T.3
Tannock, I.F.4
-
11
-
-
0028111173
-
Cloning and characterization of MN, a human tumor-associated protein with a domain homologous to carbonic anhydrase and a putative helix-loop-helix DNA binding segment
-
Pastorek J., Pastorekova S., Callebaut I., et al. Cloning and characterization of MN, a human tumor-associated protein with a domain homologous to carbonic anhydrase and a putative helix-loop-helix DNA binding segment. Oncogene 9 (1994) 2877-2888
-
(1994)
Oncogene
, vol.9
, pp. 2877-2888
-
-
Pastorek, J.1
Pastorekova, S.2
Callebaut, I.3
-
12
-
-
2542601328
-
Hypoxia-inducible carbonic anhydrase IX, marker of tumour hypoxia, survival pathway and therapy target
-
Potter C., and Harris A.L. Hypoxia-inducible carbonic anhydrase IX, marker of tumour hypoxia, survival pathway and therapy target. Cell Cycle 3 (2004) 164-167
-
(2004)
Cell Cycle
, vol.3
, pp. 164-167
-
-
Potter, C.1
Harris, A.L.2
-
13
-
-
2942707871
-
Hypoxia-inducible factor 1α/vascular endothelial growth factor axis in astrocytomas. Associations with microvessel morphometry, proliferation and prognosis
-
Korkolopoulou P., Patsouris E., Konstantinidou A.-E., et al. Hypoxia-inducible factor 1α/vascular endothelial growth factor axis in astrocytomas. Associations with microvessel morphometry, proliferation and prognosis. Neuropathol Appl Neurobiol 30 (2004) 267-278
-
(2004)
Neuropathol Appl Neurobiol
, vol.30
, pp. 267-278
-
-
Korkolopoulou, P.1
Patsouris, E.2
Konstantinidou, A.-E.3
-
14
-
-
0001872876
-
Diffusely infiltrating astrocytomas
-
Kleihues P., and Cavenee W.K. (Eds), IARC Press, Lyon
-
Cavenee W.K., Furnari F.B., Nagane M., et al. Diffusely infiltrating astrocytomas. In: Kleihues P., and Cavenee W.K. (Eds). Pathology and genetics of tumours of the nervous system (2000), IARC Press, Lyon 10-21
-
(2000)
Pathology and genetics of tumours of the nervous system
, pp. 10-21
-
-
Cavenee, W.K.1
Furnari, F.B.2
Nagane, M.3
-
15
-
-
0034671307
-
Hypoxia inducible regulation of tumor associated carbonic anhydrases
-
Wykoff C.C., Beasley N.J.P., Watson P.H., et al. Hypoxia inducible regulation of tumor associated carbonic anhydrases. Cancer Res 60 (2001) 7075-7083
-
(2001)
Cancer Res
, vol.60
, pp. 7075-7083
-
-
Wykoff, C.C.1
Beasley, N.J.P.2
Watson, P.H.3
-
16
-
-
18244362124
-
Prognostic implications of microvessel morphometry in diffuse astrocytic neoplasms
-
Korkolopoulou P., Patsouris E., Kavantzas N., et al. Prognostic implications of microvessel morphometry in diffuse astrocytic neoplasms. Neuropathol Appl Neurobiol 28 (2002) 57-66
-
(2002)
Neuropathol Appl Neurobiol
, vol.28
, pp. 57-66
-
-
Korkolopoulou, P.1
Patsouris, E.2
Kavantzas, N.3
-
17
-
-
0035573998
-
Tumour hypoxia, hypoxia signalling pathways and hypoxia inducible factor expression in human cancer
-
Giatromanolaki A., and Harris A.L. Tumour hypoxia, hypoxia signalling pathways and hypoxia inducible factor expression in human cancer. Anticancer Res 21 (2001) 4317-4324
-
(2001)
Anticancer Res
, vol.21
, pp. 4317-4324
-
-
Giatromanolaki, A.1
Harris, A.L.2
-
18
-
-
0036467999
-
Tumor hypoxia: chicken, egg or a piece of the farm?
-
Coleman C.N., Mitchell J.B., and Camphausen K. Tumor hypoxia: chicken, egg or a piece of the farm?. J Clin Oncol 20 (2002) 610-615
-
(2002)
J Clin Oncol
, vol.20
, pp. 610-615
-
-
Coleman, C.N.1
Mitchell, J.B.2
Camphausen, K.3
-
19
-
-
0345491970
-
Carbonic anhydrase IX expression, hypoxia and prognosis in patients with uterine cervical carcinomas
-
Hedley D., Pintilie M., Woo J., et al. Carbonic anhydrase IX expression, hypoxia and prognosis in patients with uterine cervical carcinomas. Clin Cancer Res 9 (2003) 5666-5674
-
(2003)
Clin Cancer Res
, vol.9
, pp. 5666-5674
-
-
Hedley, D.1
Pintilie, M.2
Woo, J.3
-
20
-
-
0035105565
-
Expression of the hypoxia-inducible and tumor-associated carbonic anhydrases in ductal carcinoma in situ of the breast
-
Wykoff C.C., Beasley N., Watson P.H., et al. Expression of the hypoxia-inducible and tumor-associated carbonic anhydrases in ductal carcinoma in situ of the breast. Am J Pathol 158 (2001) 1011-1019
-
(2001)
Am J Pathol
, vol.158
, pp. 1011-1019
-
-
Wykoff, C.C.1
Beasley, N.2
Watson, P.H.3
-
21
-
-
0035881075
-
Prognostic significance of a novel hypoxia-regulated marker, carbonic anhydrase IX, in invasive breast carcinoma
-
Chia S.K., Wykoff C.C., Watson P.H., et al. Prognostic significance of a novel hypoxia-regulated marker, carbonic anhydrase IX, in invasive breast carcinoma. J Clin Oncol 19 (2001) 3660-3668
-
(2001)
J Clin Oncol
, vol.19
, pp. 3660-3668
-
-
Chia, S.K.1
Wykoff, C.C.2
Watson, P.H.3
-
22
-
-
0242298213
-
GLUT1 and CAIX as intrinsic markers of hypoxia in bladder cancer: relationship with vascularity and proliferation as predictors of outcome of ARCON
-
Hoskin P.J., Sibtain A., Daley F.M., and Wilson G.D. GLUT1 and CAIX as intrinsic markers of hypoxia in bladder cancer: relationship with vascularity and proliferation as predictors of outcome of ARCON. Br J Cancer 89 (2003) 1290-1297
-
(2003)
Br J Cancer
, vol.89
, pp. 1290-1297
-
-
Hoskin, P.J.1
Sibtain, A.2
Daley, F.M.3
Wilson, G.D.4
-
23
-
-
0031819881
-
Immunohistochemical study of colorectal tumors for expression of a novel transmembrane carbonic anhydrase, MN/CAIX, with potential value as a marker of cell proliferation
-
Saarnio J., Parkkila S., Parkkila A.K., et al. Immunohistochemical study of colorectal tumors for expression of a novel transmembrane carbonic anhydrase, MN/CAIX, with potential value as a marker of cell proliferation. Am J Pathol 153 (1998) 279-285
-
(1998)
Am J Pathol
, vol.153
, pp. 279-285
-
-
Saarnio, J.1
Parkkila, S.2
Parkkila, A.K.3
-
24
-
-
0035503362
-
Expression of hypoxia-inducible carbonic anhydrase-9 relates to angiogenic pathways and independently to poor outcome in non-small cell lung cancer
-
Giatromanolaki A., Koukourakis M.I., Sivridis E., et al. Expression of hypoxia-inducible carbonic anhydrase-9 relates to angiogenic pathways and independently to poor outcome in non-small cell lung cancer. Cancer Res 61 (2001) 7992-7998
-
(2001)
Cancer Res
, vol.61
, pp. 7992-7998
-
-
Giatromanolaki, A.1
Koukourakis, M.I.2
Sivridis, E.3
-
25
-
-
0037315252
-
Carbonic anhydrase IX expression, a novel surrogate marker of tumor hypoxia, is associated with a poor prognosis in non-small-cell lung cancer
-
Swinson D.E.B., Jones J.L., Richardson D., et al. Carbonic anhydrase IX expression, a novel surrogate marker of tumor hypoxia, is associated with a poor prognosis in non-small-cell lung cancer. J Clin Oncol 21 (2003) 473-482
-
(2003)
J Clin Oncol
, vol.21
, pp. 473-482
-
-
Swinson, D.E.B.1
Jones, J.L.2
Richardson, D.3
-
26
-
-
0035392959
-
Carbonic anhydrase IX, an endogenous hypoxia marker, expression in head and neck squamous cell carcinoma and its relationship to hypoxia, necrosis and microvessel density
-
Beasley N.J.P., Wykoff C.C., Watson P.H., et al. Carbonic anhydrase IX, an endogenous hypoxia marker, expression in head and neck squamous cell carcinoma and its relationship to hypoxia, necrosis and microvessel density. Cancer Res 61 (2001) 5262-5267
-
(2001)
Cancer Res
, vol.61
, pp. 5262-5267
-
-
Beasley, N.J.P.1
Wykoff, C.C.2
Watson, P.H.3
-
27
-
-
0036023422
-
Coexpression of hypoxia-inducible factors 1α and 2α, carbonic anhydrase IX and vascular endothelial growth factor in nasopharyngeal carcinoma and relationship to survival
-
Hui E.P., Chan A.T.C., Pezzella F., et al. Coexpression of hypoxia-inducible factors 1α and 2α, carbonic anhydrase IX and vascular endothelial growth factor in nasopharyngeal carcinoma and relationship to survival. Clin Cancer Res 8 (2002) 2595-2604
-
(2002)
Clin Cancer Res
, vol.8
, pp. 2595-2604
-
-
Hui, E.P.1
Chan, A.T.C.2
Pezzella, F.3
-
28
-
-
9744272532
-
Carbonic anhydrase IX in early-stage non-small cell lung cancer
-
Kim S.J., Rabbani Z.N., Vollmer R.T., et al. Carbonic anhydrase IX in early-stage non-small cell lung cancer. Clin Cancer Res 10 (2004) 7925-7933
-
(2004)
Clin Cancer Res
, vol.10
, pp. 7925-7933
-
-
Kim, S.J.1
Rabbani, Z.N.2
Vollmer, R.T.3
-
29
-
-
31544475474
-
Expression of carbonic anhydrase IX in astrocytic tumors predicts poor prognosis
-
Haapasalo J.A., Nordfors K.M., Hilro M., et al. Expression of carbonic anhydrase IX in astrocytic tumors predicts poor prognosis. Clin Cancer Res 12 (2006) 473-477
-
(2006)
Clin Cancer Res
, vol.12
, pp. 473-477
-
-
Haapasalo, J.A.1
Nordfors, K.M.2
Hilro, M.3
-
30
-
-
5144231914
-
Expression of hypoxia-related tissue factors correlates with diminished survival of adjuvantly treated patients with chromosome 1p aberrant oligodendroglial neoplasms and therapeutic implications
-
Birner P., Preusser M., Gelpi E., et al. Expression of hypoxia-related tissue factors correlates with diminished survival of adjuvantly treated patients with chromosome 1p aberrant oligodendroglial neoplasms and therapeutic implications. Clin Cancer Res 10 (2004) 6567-6571
-
(2004)
Clin Cancer Res
, vol.10
, pp. 6567-6571
-
-
Birner, P.1
Preusser, M.2
Gelpi, E.3
-
31
-
-
0032514685
-
Down-regulation of transmembrane carbonic anhydrases in renal cell carcinoma cell lines by wild-type von-Hippel Lindau transgenes
-
Ivanov S.V., Kuzmin I., Wei M.H., et al. Down-regulation of transmembrane carbonic anhydrases in renal cell carcinoma cell lines by wild-type von-Hippel Lindau transgenes. Proc Natl Acad Sci U S A 95 (1998) 12596-12601
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 12596-12601
-
-
Ivanov, S.V.1
Kuzmin, I.2
Wei, M.H.3
-
32
-
-
0029761644
-
Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1
-
Forsythe J.A., Jiang B.-H., Iyer N.V., Agani F., Leung S.W., and Koos R.D. Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1. Mol Cell Biol 16 (1996) 4604-4613
-
(1996)
Mol Cell Biol
, vol.16
, pp. 4604-4613
-
-
Forsythe, J.A.1
Jiang, B.-H.2
Iyer, N.V.3
Agani, F.4
Leung, S.W.5
Koos, R.D.6
-
33
-
-
0035107383
-
Expression of hypoxia-inducible cell-surface transmembrane carbonic anhydrases in human cancer
-
Ivanov S., Liao S.Y., Ivanova A., et al. Expression of hypoxia-inducible cell-surface transmembrane carbonic anhydrases in human cancer. Am J Pathol 158 (2001) 905-919
-
(2001)
Am J Pathol
, vol.158
, pp. 905-919
-
-
Ivanov, S.1
Liao, S.Y.2
Ivanova, A.3
-
34
-
-
0036896722
-
Pimonidazole binding and tumor vascularity predict for treatment outcome in head and neck cancer
-
Kaanders J.H., Wijffels K.I., Marres H.A., et al. Pimonidazole binding and tumor vascularity predict for treatment outcome in head and neck cancer. Cancer Res 62 (2002) 7066-7074
-
(2002)
Cancer Res
, vol.62
, pp. 7066-7074
-
-
Kaanders, J.H.1
Wijffels, K.I.2
Marres, H.A.3
-
35
-
-
0034654174
-
Modulation of hypoxia-inducible factor 1 alpha expression by the epidermal growth factor/phosphatidylinositol 3-kinase/PTEN/AKT/FRAP/pathway in human prostate cancer cells: implications for tumor angiogenesis and therapeutics
-
Zhong H., Chiles K., Feldser D., et al. Modulation of hypoxia-inducible factor 1 alpha expression by the epidermal growth factor/phosphatidylinositol 3-kinase/PTEN/AKT/FRAP/pathway in human prostate cancer cells: implications for tumor angiogenesis and therapeutics. Cancer Res 60 (2000) 1541-1545
-
(2000)
Cancer Res
, vol.60
, pp. 1541-1545
-
-
Zhong, H.1
Chiles, K.2
Feldser, D.3
-
36
-
-
0029975564
-
Human MN/CA9 gene, a novel member of the carbonic anhydrase family: structure and exon to protein domain relationships
-
Opavsky R., Pastorekova S., Zelnik V., et al. Human MN/CA9 gene, a novel member of the carbonic anhydrase family: structure and exon to protein domain relationships. Genomics 33 (1996) 480-487
-
(1996)
Genomics
, vol.33
, pp. 480-487
-
-
Opavsky, R.1
Pastorekova, S.2
Zelnik, V.3
-
37
-
-
0032712997
-
Constitutive and inducible interleukin 8 expression by hypoxia and acidosis renders human pancreatic cancer cells more tumorigenic and metastatic
-
Shi Q., Abbruzzese J.L., Huang S., Fidler I.J., Xion Q., and Xie K. Constitutive and inducible interleukin 8 expression by hypoxia and acidosis renders human pancreatic cancer cells more tumorigenic and metastatic. Clin Cancer Res 5 (1999) 3711-3721
-
(1999)
Clin Cancer Res
, vol.5
, pp. 3711-3721
-
-
Shi, Q.1
Abbruzzese, J.L.2
Huang, S.3
Fidler, I.J.4
Xion, Q.5
Xie, K.6
-
38
-
-
0035261289
-
Effects of an antibody to vascular endothelial growth factor receptor-2 on survival, tumour vascularity and apoptosis in a murine model of colon carcinomatosis
-
Shaheen R.M., Tseng W.W., Vellagas R., et al. Effects of an antibody to vascular endothelial growth factor receptor-2 on survival, tumour vascularity and apoptosis in a murine model of colon carcinomatosis. Int J Oncol 18 (2001) 221-226
-
(2001)
Int J Oncol
, vol.18
, pp. 221-226
-
-
Shaheen, R.M.1
Tseng, W.W.2
Vellagas, R.3
-
39
-
-
0029035872
-
Analysis of the effects of oxygen supply and demand on hypoxic fraction of tumors
-
Secomb T.W., Hsu R., Ong E.T., Gross J.F., and Dewhirst M.W. Analysis of the effects of oxygen supply and demand on hypoxic fraction of tumors. Acta Oncol 34 (1995) 313-316
-
(1995)
Acta Oncol
, vol.34
, pp. 313-316
-
-
Secomb, T.W.1
Hsu, R.2
Ong, E.T.3
Gross, J.F.4
Dewhirst, M.W.5
-
40
-
-
0033826520
-
Role for mitochondrial oxidants as regulators of cellular metabolism
-
Nemoto S., Takeda K., Yu Z.X., Ferrans V.J., and Finkel T. Role for mitochondrial oxidants as regulators of cellular metabolism. Mol Cell Biol 20 (2000) 7311-7318
-
(2000)
Mol Cell Biol
, vol.20
, pp. 7311-7318
-
-
Nemoto, S.1
Takeda, K.2
Yu, Z.X.3
Ferrans, V.J.4
Finkel, T.5
-
41
-
-
0033848896
-
Acidic pH inhibits non-MHC-restricted killer cell functions
-
Fischer B., Muller B., Fischer K.G., Baur N., and Kreutz W. Acidic pH inhibits non-MHC-restricted killer cell functions. Clin Immunol 96 (2000) 252-263
-
(2000)
Clin Immunol
, vol.96
, pp. 252-263
-
-
Fischer, B.1
Muller, B.2
Fischer, K.G.3
Baur, N.4
Kreutz, W.5
-
42
-
-
4344699403
-
Role of carbonic anhydrase IX in human tumor cell growth, survival and invasion
-
Robertson N., Potter C., and Harris A.L. Role of carbonic anhydrase IX in human tumor cell growth, survival and invasion. Cancer Res 64 (2004) 6160-6165
-
(2004)
Cancer Res
, vol.64
, pp. 6160-6165
-
-
Robertson, N.1
Potter, C.2
Harris, A.L.3
-
43
-
-
0029775242
-
Association between tumor hypoxia and malignant progression in advanced cancer of the uterine cervix
-
Höckel M., Schlenger K., Aral B., Mitze M., Schaffer U., and Vaupel P. Association between tumor hypoxia and malignant progression in advanced cancer of the uterine cervix. Cancer Res 56 (1996) 4509-4515
-
(1996)
Cancer Res
, vol.56
, pp. 4509-4515
-
-
Höckel, M.1
Schlenger, K.2
Aral, B.3
Mitze, M.4
Schaffer, U.5
Vaupel, P.6
-
44
-
-
0030059969
-
Microvessel density is a prognostic indicator for patients with astroglial brain tumors
-
Leon S.P., Folkerth R.D., and Black P.M. Microvessel density is a prognostic indicator for patients with astroglial brain tumors. Cancer 77 (1996) 362-372
-
(1996)
Cancer
, vol.77
, pp. 362-372
-
-
Leon, S.P.1
Folkerth, R.D.2
Black, P.M.3
|