Genetic aberrations defined by comparative genomic hybridization distinguish long-term from typical survivors of glioblastoma

Cancer Research

Volumn 62, Issue 21, 2002, Pages 6205-6210

  Burton, Eric C ^a   Lamborn, Kathleen R ^a   Feuerstein, Burt G ^a   Prados, Michael ^a   Scott, James ^a   Forsyth, Peter ^a   Passe, Sandra ^a   Jenkins, Robert B ^a   Aldape, Ken D ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADOLESCENT; ADULT; AGED; ARTICLE; CANCER SURVIVAL; CHILD; CHROMOSOME 10Q; CHROMOSOME 19Q; CHROMOSOME 6Q; CHROMOSOME 7; CHROMOSOME ABERRATION; CHROMOSOME LOSS; CLINICAL ARTICLE; COMPARATIVE GENOMIC HYBRIDIZATION; CONTROLLED STUDY; DNA HYBRIDIZATION; GENE FREQUENCY; GENETIC DAMAGE; GENETIC SCREENING; GLIOBLASTOMA; HUMAN; HUMAN TISSUE; INFANT; PRIORITY JOURNAL; SURVIVAL TIME;

ADOLESCENT; ADULT; AGED; BRAIN NEOPLASMS; CHILD; CHILD, PRESCHOOL; CHROMOSOME ABERRATIONS; GLIOBLASTOMA; HUMANS; INFANT; MIDDLE AGED; MULTIVARIATE ANALYSIS; NUCLEIC ACID HYBRIDIZATION; SURVIVAL RATE;

EID: 0036828260     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (49)

1. Prados, M. D., and Levin. V. Biology and treatment of malignant glioma. Semin. Oncol., 27: 1-10, 2000.
2. Central Brain Tumor Registry of the United States. Statisical Report: Primary Brain Tumors of the United States, 1992-1997. Chicago, IL: Central Brain Tumor Registry of the United States, 2000.
3. Baxendine-Jones, J., Campbell, I. and Ellison, D. p53 status has no prognostic significance in glioblastomas treated with radiotherapy. Clin. Neuropathol., 16: 332-336, 1997
4. Simmons, M. L., Lamborn, K. R., Takahashi, M., Chen, P., Israel, M. A., Berger, M. S., Godfrey, T., Nigro, J., Prados, M., Chang, S., Barker, F. G., II, and Aldape, K. Analysis of complex relationships between age, p53, epidermal growth factor receptor, and survival in glioblastoma patients. Cancer Res., 61: 1122-1128, 2001.
5. Smith, J. S., Tachibana, I., Passe, S. M., Huntley, B. K., Borell, T. J., Iturria, N., O'Fallon, J. R., Schaefer, P. L., Scheithauer, B. W., James. C. D., Buckner, J. C., and Jenkins, R. B. PTEN mutation, EGFR amplification, and outcome in patients with anaplastic astrocytoma and glioblastoma multiforme. J. Natl. Cancer Inst., 93: 1246-1256, 2001.
6. Kleihues, P. C., and Webster, K. Pathology and Genetics of Tumours of the Nervous System. Lyon, France: IARC, 2000.
7. Ekstrand, A. J., James, C. D., Cavenee, W. K., Seliger, B., Pettersson, R. F., and Collins, V. P. Genes for epidermal growth factor receptor, transforming growth factor α, and epidermal growth factor and their expression in human gliomas in vivo. Cancer Res., 51: 2164-2172, 1991.
8. Wiltshire, R. N., Rasheed, B. K., Friedman, H. S., Friedman, A. H., and Bigner, S. H. Comparative genetic patterns of glioblastoma multiforme: Potential diagnostic tool for tumor classification. Neuro-oncol., 2: 164-173, 2000.
9. Mohapatra, G., Bollen, A. W., Kim, D. H., Lamborn, K., Moore, D. H., Prados, M. D., and Feuerstein, B. G. Genetic analysis of glioblastoma multiforme provides evidence for subgroups within the grade. Genes Chromosomes Cancer, 21: 195-206, 1998.
10. Chandler, K. L., Prados, M. D., Malec, M., and Wilson, C. B. Long-term survival in patients with glioblastoma multiforme. Neurosurgery, 32: 716-720: discussion, 720, 1993.
11. Morita, M., Rosenblum, M. K., Bilsky, M. H., Fraser, R. A., and Rosenfeld, M. R. Long-term survivors of glioblastoma multiforme: Clinical and molecular characteristics. J. Neuro-Oncol., 27: 259-266, 1996.
12. Scott, J. N., Rewcastle, N. B., Brasher, P. M., Fulton, D., Hagen, N. A., MacKinnon, J. A., Hamilton. M., Cairncross, G. G., and Forsyth, P. Long-term glioblastoma multiforme survivors: A population-based study. Can. J. Neuroi. Sci., 25: 197-201, 1998.
13. Scott, J. N., Rewcastle, N. B., Brasher, P. M., Fulton, D., MacKinnon, J. A., Hamilton, M., Cairncross, J. G., and Forsyth, P. Which glioblastoma multiforme patient will become a long-term survivor? A population-based study. Ann. Neurol., 46: 183-188, 1999.
14. Vertosick, F. T., Jr., and Selker, R. G. Long-term survival after the diagnosis of malignant glioma: A series of 22 patients surviving more than 4 years after diagnosis. Surg. Neurol., 38: 359-363, 1992.
15. Salvati, M., Cervoni, L., Artico, M., Caruso, R., and Gagliardi, F. M. Long-term survival in patients with supratentorial glioblastoma. J. Neuro-oncol., 36: 61-64, 1998.
16. Burton, E. C., Lamborn, K. R., Forsyth, P., Scott, J., O'Campo, J., Uyehara-Lock, J., Prados, M., Berger, M., Passe, S., Uhm, J., O'Neill, B. P., Jenkins, R. B., and Aldape, K. D. Aberrant p53, mdm2, and proliferation differ in glioblastomas from long-term compared with typical survivors. Clin. Cancer Res., 8: 180-187, 2002.
17. Kraus, J. A., Wenghoefer, M., Schmidt, M. C., von Deimling, A., Berweiler, U., Roggendorf, W., Diete, S., Dietzmann, K., Muller, B., Heuser, K., Reifenberger, G., and Schlegel, U. Long-term survival of glioblastoma multiforme: Importance of histopathological reevaluation. J. Neurol. 247: 455-460, 2000.
18. Hirose, Y., Aldape, K., Takahashi, M., Berger, M. S., and Feuerstein, B. G. Tissue microdissection and degenerate oligonucleotide primed-polymerase chain reaction (DOP-PCR) is an effective method to analyze genetic aberrations in invasive tumors. J. Mol. Diagn., 3: 62-67, 2001.
19. Cairncross, J. G., Ueki, K., Zlatescu, M. C., Lisle, D. K., Finkelstein, D. M., Hammond, R. R., Silver, J. S., Stark, P. C., Macdonald, D. R., Ino. Y., Ramsay, D. A., and Louis, D. N. Specific genetic predictors of chemotherapeutic response and survival in patients with anaplastic oligodendrogliomas. J. Natl. Cancer Inst., 90: 1473-1479, 1998.
20. Smith, J. S., Perry, A., Borell, T. J., Lee, H. K., O'Fallon, J., Hosek, S. M., Kimmel, D., Yates, A., Burger, P. C., Scheithauer, B. W., and Jenkins, R. B. Alterations of chromosome arms 1p and 19q as predictors of survival in oligodendrogliomas, astrocytomas, and mixed oligoastrocytomas. J. Clin. Oncol., 18: 636-645, 2000.
21. Pinkel, D., Segraves, R., Sudar, D., Clark, S., Poole, I., Kowbel, D., Collins, C., Kuo W. L., Chen C., Zhai, Y., Dairkee, S. H., Ljung, B. M., Gray, J. W., and Albertson, D. G. High resolution analysis of DNA copy number variation using comparative genomic hybridization to microarrays. Nat. Genet., 20: 207-211, 1998.
22. Squire, J. A., Arab, S., Marrano, P., Bayani, J., Karaskova, J., Taylor, M., Becker, L., Rutka, J., and Zielenska, M. Molecular cytogenetic analysis of glial tumors using spectral karyotyping and comparative genomic hybridization. Mol. Diagn., 6: 93-108, 2001.
23. Schlegel, J., Scherthan, H., Arens, N., Stumm, G., and Kiessling, M. Detection of complex genetic alterations in human glioblastoma multiforme using comparative genomic hybridization. J. Neuropathol. Exp. Neurol., 55: 81-87, 1996.
24. Schrock, E., Thiel, G., Lozanova, T., du Manoir, S., Meffert, M. C., Jauch, A., Speicher, M. R., Nurnberg, P., vogel, S., Janisch, W., et al. Comparative genomic hybridization of human malignant gliomas reveals multiple amplification sites and nonrandom chromosomal gains and losses. Am. J. Pathol., 144: 1203-1218, 1994.
25. Nishizaki, T., Ozaki, S., Harada, K., Ito, H., Arai, H., Beppe, T., and Sasaki, K. Investigation of genetic alterations associated with the grade of astrocytic tumor by comparative genomic hybridization. Genes Chromosomes Cancer. 21: 340-346, 1998.
26. Weber, R. G., Sommer, C., Albert, F. K., Kiessling, M., and Cremer, T. Clinically distinct subgroups of glioblastoma multiforme studied by comparative genomic hybridization. Lab. Investig., 74: 108-119, 1996.
27. Liu, L. Ichimura, K., Pettersson, E. H., and Collins, V. P. Chromosome 7 rearrangements in glioblastomas: Loci adjacent to EGFR are independently amplified. J. Neuropathol. Exp. Neurol., 57: 1138-1145, 1998.
28. Collins, V. P. Progression as exemplified by human astrocytic tumors. Semin. Cancer Biol., 9: 267-276, 1999.
29. Balesaria, S., Brock, C., Bower, M., Clark, J., Nicholson, S. K., Lewis, P., de Sanctis, S., Evans, H., Peterson, D., Mendoza, N., Glaser, M. G., Newlands, E. S., and Fisher, R. A. Loss of chromosome 10 is an independent prognostic factor in high-grade gliomas. Br. J. Cancer, 81: 1371-1377, 1999.
30. Noviello, C., Courjal, F., and Theillet, C. Loss of heterozygosity on the long arm of chromosome 6 in breast cancer: Possibly four regions of deletion. Clin. Cancer Res., 2: 1601-1606, 1996.
31. Healy, E., Belgaid, C., Takata, M., Harrison, D., Zhu, N. W., Burd, D. A., Rigby, H.S., Mathews, J. N., and Rees, J. L. Prognostic significance of allelic losses in primary melanoma. Oncogene. 16: 2213-2218, 1998.
32. Walker, G. J., Palmer, J. M., Walters, M. K., and Hayward, N. K. A genetic model of melanoma tumorigenesis based on allelic losses. Genes Chromosomes Cancer, 12: 134-141, 1995.
33. Chuaqui, R., Silva, M., and Emmert-Buck, M. Allelic deletion mapping on chromosome 6q and X chromosome inactivation clonality patterns in cervical intraepithelial neoplasia and invasive carcinoma. Gynecol. Oncol., 80: 364-37, 2001.
34. Allen, D. G., White, D. J., Hutchins, A. M., Scurry, J. P., Tabrizi, S. N., Garland, S. M., and Armes, J. E. Progressive genetic aberrations detected by comparative genomic hybridization in squamous cell cervical cancer. Br. J. Cancer, 83: 1659-1663, 2000.
35. Kersemackers. A, M., van de Vijver, M. J., Kenter, G. G., and Fleuren, G. J. Genetic alterations during the progression of squamous cell carcinomas of the uterine cervix. Genes Chromosomes Cancer. 26: 346-354. 1999.
36. Wooten, E. C., Fults, D., Duggirala, R., Williams, K., Kyritsis, A. P., Bondy, M. L., Levin, V. A., and O'Connell, P. A. A study of loss of heterozygosity at 70 loci in anaplastic astrocytoma and glioblastoma multiforme with implications for tumor evolution. Neuro-Oncology, 1: 169-176, 1999.
37. Miyakawa, A., Ichimura, K., Schmidt, E. E., Varmeh-Ziaie, S., and Collins, V. P. Multiple deleted regions on the long arm of chromosome 6 in astrocytic tumours. Br. J. Cancer, 82: 543-549, 2000.
38. Debiec-Rychter, M., Alwasiak, J., Liberski, P. P., Nedoszytko, B., Babinska, M., Mrozek, K., Imielinski, B., Borowska-Lehman, J., and Limon, J. Accumulation of chromosomal changes in human glioma progression. A cytogenetic study of 50 cases. Cancer Genet. Cytogenet., 85: 61-67, 1995.
39. Liang, B. C., Ross, D. A., Greenberg, H. S., Meltzer, P. S., and Trent, J. M. Evidence of allelic imbalance of chromosome 6 in human astrocytomas. Neurology, 44: 533-536, 1994.
40. Jenkins, R. B., Kimmel, D. W., Moertel, C. A., Schultz, C. G., Scheithauer, B. W., Kelly, P. J., and Dewald, G. W. A cytogenetic study of 53 human gliomas. Cancer Genet. Cytogenet., 39: 253-279, 1989.
41. Rey, J. A., Bello, M. J., de Campos, J. M., Kusak, M. E., Ramos, C., and Benitez, J. Chromosomal patterns in human malignant astrocytomas. Cancer Genet. Cytogenet., 29: 201-221, 1987.
42. Kunwar, S., Mohapatra, G., Bollen, A., Lamborn, K. R., Prados, M., and Feuerstein, B. G. Genetic subgroups of anaplastic astrocytomas correlate with patient age and survival. Cancer Res., 61: 7683-7688, 2001.
43. Huhn, S. L., Mohapatra, G., Bollen, A., Lamborn, K., Prados, M. D., and Feuerstein, B. G. Chromosomal abnormalities in glioblastoma multiforme by comparative genomic hybridization: correlation with radiation treatment outcome. Clin. Cancer Res., 5: 1435-1443, 1999.
44. Weber, R. G., Sabel, M., Reifenberger, J., Sommer, C., Oberstrass, J., Reifenberger, G., Kiessling, M., and Cremer, T. Characterization of genomic alterations associated with glioma progression by comparative genomic hybridization. Oncogene. 13: 983-994, 1996.
45. Iwabuchi, H., Sakamoto, M., Sakunaga, H., Ma, Y. Y., Carcangiu, M. L., Pinkel, D., Yang-Feng, T. L., and Gray, J. W. Genetic analysis of benign, low-grade, and high-grade ovarian tumors. Cancer Res., 55: 6172-6180, 1995.
46. Kallioniemi, A., Kallionieme, O. P., Piper, J., Tanner, M., Stokke, T., Chen, L., Smith, H. S., Pinkel, D., Gray, J. W., and Waldman, F. M. Detection and mapping of amplified DNA sequences in breast cancer by comparative genomic hybridization. Proc. Natl. Acad. Sci. USA, 91: 2156-2160. 1994.
47. Ino, Y., Zlatescu, M. C., Sasaki, H., Macdonald, D. R., Stemmer-Rachamimov, A. O., Jhung, S., et al. Long survival and therapeutic responses in patients with histologically disparate high-grade gliomas demonstrating chromosome 1p loss. J. Neurosurg., 92: 983-990, 2000.
48. Sasaki, H., Zlatescu, M. C., Betensky, R. A., Ino, Y., Cairncross, J. G., and Louis, D. N. PTEN is a target of chromosome 10q loss in anaplastic oligodendrogliomas and PTEN alterations are associated with poor prognosis. Am. J. Pathol., 159: 359-367, 2001.
49. Fujisawa, H., Kurrer, M., Reis, R. M., Yonekawa, Y., Kleihues, P., and Ohgaki, H. Acquisition of the glioblastoma phenotype during astrocytoma progression is associated with loss of heterozygosity on 10q25-qter. Am. J. Pathol., 155: 387-394, 1999.