Signaling by IL-1β+IFN-γ and ER stress converge on DP5/Hrk activation: A novel mechanism for pancreatic β-cell apoptosis

Cell Death and Differentiation

Volumn 16, Issue 11, 2009, Pages 1539-1550

  Gurzov, E N ^a   Ortis, F ^a   Cunha, D A ^a   Gosset, G ^a   Li, M ^b   Cardozo, A K ^a   Eizirik, D L ^a  

^a UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

^b SUN YAT SEN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BH3 PROTEIN; CYTOCHROME C; DEATH PROTEIN 5; HARAKIRI PROTEIN; INTERLEUKIN 1BETA; NITRIC OXIDE; PROTEIN C JUN; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR JUNB; UNCLASSIFIED DRUG; APOPTOSIS REGULATORY PROTEIN; BID3 PROTEIN, RAT; GAMMA INTERFERON; NEUROPEPTIDE; SMALL INTERFERING RNA;

ANIMAL CELL; APOPTOSIS; ARTICLE; CONTROLLED STUDY; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVATION; MITOCHONDRION; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION; UPREGULATION; ANIMAL; CYTOLOGY; ENDOPLASMIC RETICULUM; METABOLISM; WISTAR RAT;

ANIMALS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; CYTOCHROMES C; ENDOPLASMIC RETICULUM; INSULIN-SECRETING CELLS; INTERFERON-GAMMA; INTERLEUKIN-1BETA; JNK MITOGEN-ACTIVATED PROTEIN KINASES; NEUROPEPTIDES; RATS; RATS, WISTAR; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; UP-REGULATION;

EID: 70350028224     PISSN: 13509047     EISSN: 14765403     Source Type: Journal    
DOI: 10.1038/cdd.2009.99     Document Type: Article

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