Upregulation of PTEN by peroxynitrite contributes to cytokine-induced apoptosis in pancreatic β-cells

Apoptosis

Volumn 15, Issue 8, 2010, Pages 877-886

  Hou, Rongrong ^a,b   Zhang, Jing ^a   Yin, Tao ^a   Cao, Hongwei ^a   Zhang, Nanyan ^a   Li, Xiaomiao ^a   Wang, Li ^a   Xing, Ying ^a   Li, Deqiang ^a   Ji, Qiuhe ^a  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^b BETHUNE INTERNATIONAL PEACE HOSPITAL   (China)

Author keywords

Apoptosis; Cytokine; Pancreatic cell; Peroxynitrite; PTEN

Indexed keywords

3 NITROTYROSINE; CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 1BETA; N(G) METHYLARGININE; PEROXYNITRITE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B; SMALL INTERFERING RNA; STREPTOZOCIN; TUMOR NECROSIS FACTOR ALPHA; PEROXYNITROUS ACID; PHOSPHATIDYLINOSITOL 3 KINASE; PTEN PROTEIN, MOUSE;

ANIMAL CELL; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DIABETES MELLITUS; ENZYME ACTIVATION; ENZYME INHIBITION; GENETIC TRANSFECTION; MOUSE; NONHUMAN; OXIDATIVE STRESS; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN FUNCTION; UPREGULATION; ANIMAL; CELL LINE; CYTOLOGY; DRUG EFFECTS; GENETICS; METABOLISM; PHYSIOLOGY; SIGNAL TRANSDUCTION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; APOPTOSIS; CELL LINE; CYTOKINES; INSULIN-SECRETING CELLS; INTERFERON-GAMMA; INTERLEUKIN-1BETA; MICE; PEROXYNITROUS ACID; PROTO-ONCOGENE PROTEINS C-AKT; PTEN PHOSPHOHYDROLASE; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TUMOR NECROSIS FACTOR-ALPHA; UP-REGULATION; PHOSPHATIDYLINOSITOL 3-KINASES;

EID: 77956935917     PISSN: 13608185     EISSN: 1573675X     Source Type: Journal    
DOI: 10.1007/s10495-010-0510-z     Document Type: Article

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