메뉴 건너뛰기




Volumn 56, Issue 2, 2015, Pages 149-170

Nanomaterials and neurodegeneration

Author keywords

Nanodevices; Nanomaterials; Nanoparticles; Neurodegenerative diseases; Neurotoxicity; Oxidative stress

Indexed keywords

BETA TUBULIN; CARBON NANOTUBE; COPPER NANOPARTICLE; COPPER OXIDE NANOPARTICLE; F ACTIN; GLUTATHIONE; LACTATE DEHYDROGENASE; MAGNETIC NANOPARTICLE; MALONALDEHYDE; MONOCYTE CHEMOTACTIC PROTEIN 1; MULTI WALLED NANOTUBE; NANOMATERIAL; SILICA NANOPARTICLE; SILVER NANOPARTICLE; SUPEROXIDE DISMUTASE; TITANIUM DIOXIDE; TITANIUM DIOXIDE NANOPARTICLE; TYROSINE 3 MONOOXYGENASE; UNCLASSIFIED DRUG; ZINC OXIDE NANOPARTICLE; METAL NANOPARTICLE; REACTIVE OXYGEN METABOLITE; SILICON DIOXIDE; TITANIUM; ZINC OXIDE;

EID: 84925342593     PISSN: 08936692     EISSN: 10982280     Source Type: Journal    
DOI: 10.1002/em.21931     Document Type: Review
Times cited : (81)

References (163)
  • 2
    • 84872360422 scopus 로고    scopus 로고
    • Silica nanoparticles-induced cytotoxicity, oxidative stress and apoptosis in cultured A431 and A549 cells
    • Ahamed M. 2013. Silica nanoparticles-induced cytotoxicity, oxidative stress and apoptosis in cultured A431 and A549 cells. Hum Exp Toxicol 32:186-195.
    • (2013) Hum Exp Toxicol , vol.32 , pp. 186-195
    • Ahamed, M.1
  • 4
    • 77956414879 scopus 로고    scopus 로고
    • Nanotoxicity of pure silica mediated through oxidant generation rather than glutathione depletion in human lung epithelial cells
    • Akhtar MJ, Ahamed M, Kumar S, Siddiqui H, Patil G, Ashquin M, Ahmad I. 2010. Nanotoxicity of pure silica mediated through oxidant generation rather than glutathione depletion in human lung epithelial cells. Toxicology 276:95-102.
    • (2010) Toxicology , vol.276 , pp. 95-102
    • Akhtar, M.J.1    Ahamed, M.2    Kumar, S.3    Siddiqui, H.4    Patil, G.5    Ashquin, M.6    Ahmad, I.7
  • 5
    • 84888382800 scopus 로고    scopus 로고
    • Alzheimer's disease: Pathophysiology and applications of magnetic nanoparticles as MRI theranostic agents
    • Amiri H, Saeidi K, Borhani P, Manafirad A, Ghavami M, Zerbi V. 2013. Alzheimer's disease: Pathophysiology and applications of magnetic nanoparticles as MRI theranostic agents. ACS Chem Neurosci 4:1417-1429.
    • (2013) ACS Chem Neurosci , vol.4 , pp. 1417-1429
    • Amiri, H.1    Saeidi, K.2    Borhani, P.3    Manafirad, A.4    Ghavami, M.5    Zerbi, V.6
  • 7
    • 84864457874 scopus 로고    scopus 로고
    • Cognitive impairment in rats induced by nano-CuO and its possible mechanisms
    • An L, Liu S, Yang Z, Zhang T. 2012 Cognitive impairment in rats induced by nano-CuO and its possible mechanisms. Toxicol Lett 3;213:220-227.
    • (2012) Toxicol Lett 3 , vol.213 , pp. 220-227
    • An, L.1    Liu, S.2    Yang, Z.3    Zhang, T.4
  • 9
    • 84880510283 scopus 로고    scopus 로고
    • Toward single-walled carbon nanotube-gadolinium complex as advanced MRI contrast agents: Pharmacodynamics and global genomic response in small animals
    • Avti PK, Talukdar Y, Sirotkin MV, Shroyer KR, Sitharaman B. 2013. Toward single-walled carbon nanotube-gadolinium complex as advanced MRI contrast agents: Pharmacodynamics and global genomic response in small animals. J Biomed Mater Res Part B 101B:1039-1049.
    • (2013) J Biomed Mater Res Part B , vol.101 B , pp. 1039-1049
    • Avti, P.K.1    Talukdar, Y.2    Sirotkin, M.V.3    Shroyer, K.R.4    Sitharaman, B.5
  • 12
    • 0035371978 scopus 로고    scopus 로고
    • Poly-nbutyl cyanoacrylate nanoparticles: A mechanistic study of polymerization and particle formation
    • Behan N, Birkinshaw C, Clarke N. 2001. Poly-nbutyl cyanoacrylate nanoparticles: A mechanistic study of polymerization and particle formation. Biomaterials 22:1335-1344.
    • (2001) Biomaterials , vol.22 , pp. 1335-1344
    • Behan, N.1    Birkinshaw, C.2    Clarke, N.3
  • 14
    • 63149175757 scopus 로고    scopus 로고
    • European NanoBioPharmaceutics Research Initiative. Delivery of peptide and protein drugs over the blood-brain barrier
    • Brasnjevic I, Steinbusch HW, Schmitz C, Martinez-Martinez P. 2009. European NanoBioPharmaceutics Research Initiative. Delivery of peptide and protein drugs over the blood-brain barrier. Prog Neurobiol 87:212-251.
    • (2009) Prog Neurobiol , vol.87 , pp. 212-251
    • Brasnjevic, I.1    Steinbusch, H.W.2    Schmitz, C.3    Martinez-Martinez, P.4
  • 15
    • 84887686466 scopus 로고    scopus 로고
    • Inflammation and gene expression in the rat lung after instillation of silica nanoparticles: Effect of size, dispersion medium and particle surface charge
    • Brown DM, Kanase N, Gaiser B, Johnston H, Stone V. 2014. Inflammation and gene expression in the rat lung after instillation of silica nanoparticles: Effect of size, dispersion medium and particle surface charge. Toxicol Lett 224:147-156.
    • (2014) Toxicol Lett , vol.224 , pp. 147-156
    • Brown, D.M.1    Kanase, N.2    Gaiser, B.3    Johnston, H.4    Stone, V.5
  • 16
    • 0034756495 scopus 로고    scopus 로고
    • Effects of metals on the nervous system of humans and animals
    • Carpenter DO. 2001. Effects of metals on the nervous system of humans and animals. Int J Occup Med Environ Health 14:209-218.
    • (2001) Int J Occup Med Environ Health , vol.14 , pp. 209-218
    • Carpenter, D.O.1
  • 17
    • 84921832523 scopus 로고    scopus 로고
    • Liposomal-formulated curcumin [Lipocurc™] targeting HDAC (histone deacetylase) prevents apoptosis and improves motor deficits in Park 7 (DJ-1)-knockout rat model of Parkinson's disease: Implications for epigenetics-based nanotechnology-driven drug platform
    • Chiu S, Terpstra KJ, Bureau Y, Hou J, Raheb H, Cernvosky Z, Badmeav V, Copen J, Husni M, Woodbury-Farina M. 2013. Liposomal-formulated curcumin [Lipocurc™] targeting HDAC (histone deacetylase) prevents apoptosis and improves motor deficits in Park 7 (DJ-1)-knockout rat model of Parkinson's disease: Implications for epigenetics-based nanotechnology-driven drug platform. J Complement Integr Med 10:75-88.
    • (2013) J Complement Integr Med , vol.10 , pp. 75-88
    • Chiu, S.1    Terpstra, K.J.2    Bureau, Y.3    Hou, J.4    Raheb, H.5    Cernvosky, Z.6    Badmeav, V.7    Copen, J.8    Husni, M.9    Woodbury-Farina, M.10
  • 18
    • 84875296181 scopus 로고    scopus 로고
    • Comparative absorption, distribution, and excretion of titanium dioxide and zinc oxide nanoparticles after repeated oral administration
    • Cho WS, Kang BC, Lee JK, Jeong J, Che JH, Seok SH. 2013. Comparative absorption, distribution, and excretion of titanium dioxide and zinc oxide nanoparticles after repeated oral administration. Part Fibre Toxicol 10:9.
    • (2013) Part Fibre Toxicol , vol.10 , pp. 9
    • Cho, W.S.1    Kang, B.C.2    Lee, J.K.3    Jeong, J.4    Che, J.H.5    Seok, S.H.6
  • 19
    • 54949095756 scopus 로고    scopus 로고
    • Transient pulmonary fibrogenic effect induced by intratracheal instillation of ultrafine amorphous silica in A/J mice
    • Choi M, Cho WS, Han BS, Cho M, Kim SY, Yi JY, Ahn B, Kim SH, Jeong J. 2008. Transient pulmonary fibrogenic effect induced by intratracheal instillation of ultrafine amorphous silica in A/J mice. Toxicol Lett 182:97-101.
    • (2008) Toxicol Lett , vol.182 , pp. 97-101
    • Choi, M.1    Cho, W.S.2    Han, B.S.3    Cho, M.4    Kim, S.Y.5    Yi, J.Y.6    Ahn, B.7    Kim, S.H.8    Jeong, J.9
  • 20
    • 77951710094 scopus 로고    scopus 로고
    • Silica-based nanoparticle uptake and cellular response by primary microglia
    • Choi J, Zheng Q, Katz HE, Guilart, TR. 2010. Silica-based nanoparticle uptake and cellular response by primary microglia. Environ Health Perspect 118:589-595.
    • (2010) Environ Health Perspect , vol.118 , pp. 589-595
    • Choi, J.1    Zheng, Q.2    Katz, H.E.3    Guilart, T.R.4
  • 21
    • 84896323678 scopus 로고    scopus 로고
    • Assessment of cellular responses after short- and long-term exposure to silver nanoparticles in human neuroblastoma (SH-SY5Y) and astrocytoma (D384) cells
    • Coccini T, Manzo L, Bellotti V, De Simone U. 2014. Assessment of cellular responses after short- and long-term exposure to silver nanoparticles in human neuroblastoma (SH-SY5Y) and astrocytoma (D384) cells. Sci World J 2014:259765.
    • (2014) Sci World J , vol.2014 , pp. 259765
    • Coccini, T.1    Manzo, L.2    Bellotti, V.3    De Simone, U.4
  • 22
    • 77950338981 scopus 로고    scopus 로고
    • DNA repair in premature aging disorders and neurodegeneration
    • Coppedè F, Migliore L. 2010. DNA repair in premature aging disorders and neurodegeneration. Curr Aging Sci 3:3-19.
    • (2010) Curr Aging Sci , vol.3 , pp. 3-19
    • Coppedè, F.1    Migliore, L.2
  • 23
    • 84905393725 scopus 로고    scopus 로고
    • Engineered nanoparticles. How brain friendly is this new guest?
    • Cupaioli FA, Zucca FA, Boraschi D, Zecca L. 2014. Engineered nanoparticles. How brain friendly is this new guest?. Prog Neurobiol 119-120:20-38.
    • (2014) Prog Neurobiol , vol.119-120 , pp. 20-38
    • Cupaioli, F.A.1    Zucca, F.A.2    Boraschi, D.3    Zecca, L.4
  • 26
    • 51749108879 scopus 로고    scopus 로고
    • Role of copper in human neurological disorders
    • Desai V, Kaler SG. 2008. Role of copper in human neurological disorders. Am J Clin Nutr 88:855S-858S.
    • (2008) Am J Clin Nutr , vol.88 , pp. 855S-858S
    • Desai, V.1    Kaler, S.G.2
  • 29
    • 70349394917 scopus 로고    scopus 로고
    • Oxidative stress of silica nanoparticles in human bronchial epithelial cell, Beas-2B
    • Eom HJ, Choi J. 2009. Oxidative stress of silica nanoparticles in human bronchial epithelial cell, Beas-2B. Toxicol In Vitro 23:1326-1332.
    • (2009) Toxicol In Vitro , vol.23 , pp. 1326-1332
    • Eom, H.J.1    Choi, J.2
  • 30
    • 84887454340 scopus 로고    scopus 로고
    • Drug development in Parkinson's disease: From emerging molecules to innovative drug delivery systems
    • Garbayo E, Ansorena E, Blanco-Prieto MJ. 2013. Drug development in Parkinson's disease: From emerging molecules to innovative drug delivery systems. Maturitas 76:272-278.
    • (2013) Maturitas , vol.76 , pp. 272-278
    • Garbayo, E.1    Ansorena, E.2    Blanco-Prieto, M.J.3
  • 31
    • 84865578615 scopus 로고    scopus 로고
    • Distribution and systemic effects of intranasally administered 25 nm silver nanoparticles in adult mice
    • Genter MB, Newman NC, Shertzer HG, Ali SF, Bolon B. 2012. Distribution and systemic effects of intranasally administered 25 nm silver nanoparticles in adult mice. Toxicol Pathol 40:1004-1013.
    • (2012) Toxicol Pathol , vol.40 , pp. 1004-1013
    • Genter, M.B.1    Newman, N.C.2    Shertzer, H.G.3    Ali, S.F.4    Bolon, B.5
  • 34
    • 84865452207 scopus 로고    scopus 로고
    • Ferritin up-regulation and transient production in cultured brain astrocytes after loading with iron oxide nanoparticles
    • Geppert M, Hohnholt MC, Nürnberger S, Dringen R. 2012. Ferritin up-regulation and transient production in cultured brain astrocytes after loading with iron oxide nanoparticles. Acta Biomater 8:3832-3839.
    • (2012) Acta Biomater , vol.8 , pp. 3832-3839
    • Geppert, M.1    Hohnholt, M.C.2    Nürnberger, S.3    Dringen, R.4
  • 35
    • 84892163616 scopus 로고    scopus 로고
    • Autophagy as an essential cellular antioxidant pathway in neurodegenerative disease
    • Giordano S, Darley-Usmar V, Zhang J. 2013. Autophagy as an essential cellular antioxidant pathway in neurodegenerative disease. Redox Biol 2:82-90.
    • (2013) Redox Biol , vol.2 , pp. 82-90
    • Giordano, S.1    Darley-Usmar, V.2    Zhang, J.3
  • 36
    • 84877103526 scopus 로고    scopus 로고
    • Thinking laterally about neurodegenerative proteinopathies
    • Golde TE, Borchelt DR, Giasson BI, Lewis J. 2013. Thinking laterally about neurodegenerative proteinopathies. J Clin Invest 123:1847-1855.
    • (2013) J Clin Invest , vol.123 , pp. 1847-1855
    • Golde, T.E.1    Borchelt, D.R.2    Giasson, B.I.3    Lewis, J.4
  • 37
    • 84875697145 scopus 로고    scopus 로고
    • Metal dyshomeostasis and oxidative stress in Alzheimer's disease
    • Greenough MA, Camakaris J, Bush AI. 2013. Metal dyshomeostasis and oxidative stress in Alzheimer's disease. Neurochem Int 62:540-555.
    • (2013) Neurochem Int , vol.62 , pp. 540-555
    • Greenough, M.A.1    Camakaris, J.2    Bush, A.I.3
  • 39
    • 0021351203 scopus 로고
    • Oxygen toxicity, oxygen radicals,transition metals and diseases
    • Halliwell B, Gutteridge JM. 1984. Oxygen toxicity, oxygen radicals, transition metals and diseases. Biochem J 219:1-14.
    • (1984) Biochem J , vol.219 , pp. 1-14
    • Halliwell, B.1    Gutteridge, J.M.2
  • 40
    • 84899131663 scopus 로고    scopus 로고
    • The effect of size on Ag nanosphere toxicity in macrophage cell models and lung epithelial cell lines is dependent on particle dissolution
    • Hamilton RF, Buckingham S, Holian A. 2014. The effect of size on Ag nanosphere toxicity in macrophage cell models and lung epithelial cell lines is dependent on particle dissolution. Int J Mol Sci 15:6815-6830.
    • (2014) Int J Mol Sci , vol.15 , pp. 6815-6830
    • Hamilton, R.F.1    Buckingham, S.2    Holian, A.3
  • 41
    • 0037135111 scopus 로고    scopus 로고
    • The amyloid hypothesis of Alzheimer's disease: Progress and problems on the road to therapeutics
    • Hardy J, Selkoe DJ. 2002. The amyloid hypothesis of Alzheimer's disease: Progress and problems on the road to therapeutics. Science 297:353-356.
    • (2002) Science , vol.297 , pp. 353-356
    • Hardy, J.1    Selkoe, D.J.2
  • 43
    • 77952356102 scopus 로고    scopus 로고
    • The cytosolic redox state of astrocytes: Maintenance, regulation and functional implications for metabolite trafficking
    • Hirrlinger J, Dringen R. 2010. The cytosolic redox state of astrocytes: Maintenance, regulation and functional implications for metabolite trafficking. Brain Res Rev 63:177-188.
    • (2010) Brain Res Rev , vol.63 , pp. 177-188
    • Hirrlinger, J.1    Dringen, R.2
  • 44
    • 77955560497 scopus 로고    scopus 로고
    • Effects of iron chelators, iron salts, and iron oxide nanoparticles on the proliferation and the iron content of oligodendroglial OLN-93 cells
    • Hohnholt M, Geppert M, Dringen R. 2010. Effects of iron chelators, iron salts, and iron oxide nanoparticles on the proliferation and the iron content of oligodendroglial OLN-93 cells. Neurochem Res 35:1259-1268.
    • (2010) Neurochem Res , vol.35 , pp. 1259-1268
    • Hohnholt, M.1    Geppert, M.2    Dringen, R.3
  • 46
    • 79960167888 scopus 로고    scopus 로고
    • Lactoferrin conjugated PEG-PLGA nanoparticles for brain delivery: Preparation, characterization and efficacy in Parkinson's disease
    • Hu K, Shi Y, Jiang W, Han J, Huang S, Jiang X. 2011. Lactoferrin conjugated PEG-PLGA nanoparticles for brain delivery: Preparation, characterization and efficacy in Parkinson's disease. Int J Pharm 415:273-283.
    • (2011) Int J Pharm , vol.415 , pp. 273-283
    • Hu, K.1    Shi, Y.2    Jiang, W.3    Han, J.4    Huang, S.5    Jiang, X.6
  • 47
    • 70349501374 scopus 로고    scopus 로고
    • Neuroprotection in a 6-hydroxydopamine-lesioned Parkinson model using lactoferrin-modified nanoparticles
    • Huang R, Han L, Li J, Ren F, Ke W, Jiang C, Pei Y. 2009. Neuroprotection in a 6-hydroxydopamine-lesioned Parkinson model using lactoferrin-modified nanoparticles. J Gene Med 11:754-763.
    • (2009) J Gene Med , vol.11 , pp. 754-763
    • Huang, R.1    Han, L.2    Li, J.3    Ren, F.4    Ke, W.5    Jiang, C.6    Pei, Y.7
  • 48
    • 84888129490 scopus 로고    scopus 로고
    • The genotype-dependent influence of functionalized multiwalled carbon nanotubes on fetal development
    • Huang X, Zhang F, Sun X, Choi KY, Niu G, Zhang G, Guo J, Lee S, Chen X. 2014. The genotype-dependent influence of functionalized multiwalled carbon nanotubes on fetal development. Biomaterials 35:856-865.
    • (2014) Biomaterials , vol.35 , pp. 856-865
    • Huang, X.1    Zhang, F.2    Sun, X.3    Choi, K.Y.4    Niu, G.5    Zhang, G.6    Guo, J.7    Lee, S.8    Chen, X.9
  • 51
    • 84873053242 scopus 로고    scopus 로고
    • Potential therapeutic effect of nanobased formulation of rivastigmine on rat model of Alzheimer's disease
    • Ismail MF, Elmeshad AN, Salem NA. 2013. Potential therapeutic effect of nanobased formulation of rivastigmine on rat model of Alzheimer's disease. Int J Nanomed 8:393-406.
    • (2013) Int J Nanomed , vol.8 , pp. 393-406
    • Ismail, M.F.1    Elmeshad, A.N.2    Salem, N.A.3
  • 52
    • 27644542061 scopus 로고    scopus 로고
    • Medical application of functionalized magnetic nanoparticles
    • Ito A, Shinkai M, Honda H, Kobayashi T. 2005. Medical application of functionalized magnetic nanoparticles. J Biosci Bioeng 100:1-11.
    • (2005) J Biosci Bioeng , vol.100 , pp. 1-11
    • Ito, A.1    Shinkai, M.2    Honda, H.3    Kobayashi, T.4
  • 54
    • 44449157087 scopus 로고    scopus 로고
    • Effect of complexing agents on properties of electroless Ni-P deposits
    • Ji SL, Ye CH. 2008. Effect of complexing agents on properties of electroless Ni-P deposits. J Mater Sci Technol 24:457-460.
    • (2008) J Mater Sci Technol , vol.24 , pp. 457-460
    • Ji, S.L.1    Ye, C.H.2
  • 55
    • 84886718997 scopus 로고    scopus 로고
    • The emerging role of astrocytes in the metal homeostasis in brain
    • Jones CE. 2012 The emerging role of astrocytes in the metal homeostasis in brain. Global J Inorg Chem 3:4.
    • (2012) Global J Inorg Chem , vol.3 , pp. 4
    • Jones, C.E.1
  • 56
    • 84868210145 scopus 로고    scopus 로고
    • Demonstration of an olfactory bulb-brain translocation pathway for ZnO nanoparticles in rodent cells in vitro and in vivo
    • Kao YY, Cheng TJ, Yang DM, Wang CT, Chiung YM, Liu PS. 2012. Demonstration of an olfactory bulb-brain translocation pathway for ZnO nanoparticles in rodent cells in vitro and in vivo. J Mol Neurosci 48:464-471.
    • (2012) J Mol Neurosci , vol.48 , pp. 464-471
    • Kao, Y.Y.1    Cheng, T.J.2    Yang, D.M.3    Wang, C.T.4    Chiung, Y.M.5    Liu, P.S.6
  • 58
    • 84884283916 scopus 로고    scopus 로고
    • In vivo nanoneurotoxicity screening using oxidative stress and neuroinflammation paradigms
    • Kim Y, Kong SD, Chen LH, Pisanic TR 2nd, Jin S, Shubayev VI. 2013. In vivo nanoneurotoxicity screening using oxidative stress and neuroinflammation paradigms. Nanomedicine 9:1057-1066.
    • (2013) Nanomedicine , vol.9 , pp. 1057-1066
    • Kim, Y.1    Kong, S.D.2    Chen, L.H.3    Pisanic, T.R.4    Jin, S.5    Shubayev, V.I.6
  • 59
    • 42649143562 scopus 로고    scopus 로고
    • Twenty-eight-day oral toxicity, genotoxicity, and gender-related tissue distribution of silver nanoparticles in Sprague-Dawley rats
    • Kim YS, Kim JS, Cho HS, Rha DS, Kim JM, Park JD, Choi BS, Lim R, Chang HK, Chung YH, et al. 2008. Twenty-eight-day oral toxicity, genotoxicity, and gender-related tissue distribution of silver nanoparticles in Sprague-Dawley rats. Inhal Toxicol 20:575-583.
    • (2008) Inhal Toxicol , vol.20 , pp. 575-583
    • Kim, Y.S.1    Kim, J.S.2    Cho, H.S.3    Rha, D.S.4    Kim, J.M.5    Park, J.D.6    Choi, B.S.7    Lim, R.8    Chang, H.K.9    Chung, Y.H.10
  • 61
    • 79251648024 scopus 로고    scopus 로고
    • Pathology, clinical features and treatments of congenital copper metabolic disorders-focus on neurologic aspects
    • Kodama H, Fujisawa C, Bhadhprasit W. 2011. Pathology, clinical features and treatments of congenital copper metabolic disorders-focus on neurologic aspects. Brain Dev 33:243-251.
    • (2011) Brain Dev , vol.33 , pp. 243-251
    • Kodama, H.1    Fujisawa, C.2    Bhadhprasit, W.3
  • 62
    • 6344294066 scopus 로고    scopus 로고
    • Influence of the surface properties on nanoparticle-mediated transport of drugs to the brain
    • Kreuter J. 2004. Influence of the surface properties on nanoparticle-mediated transport of drugs to the brain. J Nanosci Nanotechnol 4:484-488.
    • (2004) J Nanosci Nanotechnol , vol.4 , pp. 484-488
    • Kreuter, J.1
  • 65
    • 69249190460 scopus 로고    scopus 로고
    • Exposure to titanium dioxide and other metallic oxide nanoparticles induces cytotoxicity on human neural cells and fibroblasts
    • Lai JC, Lai MB, Jandhyam S, Dukhande VV, Bhushan A, Daniels CK, Leung SW. 2008. Exposure to titanium dioxide and other metallic oxide nanoparticles induces cytotoxicity on human neural cells and fibroblasts. Int J Nanomed 3:533-545.
    • (2008) Int J Nanomed , vol.3 , pp. 533-545
    • Lai, J.C.1    Lai, M.B.2    Jandhyam, S.3    Dukhande, V.V.4    Bhushan, A.5    Daniels, C.K.6    Leung, S.W.7
  • 66
    • 84655162221 scopus 로고    scopus 로고
    • Magnetic field-induced acceleration of the accumulation of magnetic iron oxide nanoparticles by cultured brain astrocytes
    • Lamkowsky MC, Geppert M, Schmidt MM, Dringen R. 2012. Magnetic field-induced acceleration of the accumulation of magnetic iron oxide nanoparticles by cultured brain astrocytes. J Biomed Mater Res A 100A:323-334.
    • (2012) J Biomed Mater Res A , vol.100 A , pp. 323-334
    • Lamkowsky, M.C.1    Geppert, M.2    Schmidt, M.M.3    Dringen, R.4
  • 68
    • 80053578495 scopus 로고    scopus 로고
    • The comparative effects of mesoporous silica nanoparticles and colloidal silica on inflammation and apoptosis
    • Lee S, Yun HS, Kim SH. The comparative effects of mesoporous silica nanoparticles and colloidal silica on inflammation and apoptosis. Biomaterials 32:9434-9443.
    • Biomaterials , vol.32 , pp. 9434-9443
    • Lee, S.1    Yun, H.S.2    Kim, S.H.3
  • 69
    • 84893007058 scopus 로고    scopus 로고
    • SiO2 nanoparticles change colour preference and cause Parkinson's-like behaviour in zebrafish
    • Li X, Liu B, Li XL, Li YX, Sun MZ, Chen DY, Zhao X, Feng XZ. 2014. SiO2 nanoparticles change colour preference and cause Parkinson's-like behaviour in zebrafish. Sci Rep 4:3810.
    • (2014) Sci Rep , vol.4 , pp. 3810
    • Li, X.1    Liu, B.2    Li, X.L.3    Li, Y.X.4    Sun, M.Z.5    Chen, D.Y.6    Zhao, X.7    Feng, X.Z.8
  • 70
    • 77956161513 scopus 로고    scopus 로고
    • Endothelial cells dysfunction induced by silica nanoparticles through oxidative stress via JNK/P53 and NF-kB pathways
    • Liu X, Sun J. 2010. Endothelial cells dysfunction induced by silica nanoparticles through oxidative stress via JNK/P53 and NF-kB pathways. Biomaterials 31:8198-8209.
    • (2010) Biomaterials , vol.31 , pp. 8198-8209
    • Liu, X.1    Sun, J.2
  • 71
    • 84894182486 scopus 로고    scopus 로고
    • In vitro and in vivo studies on the transport of PEGylated silica nanoparticles across the blood-brain barrier
    • Liu D, Lin B, Shao W, Zhu Z, Ji T, Yang C. 2014. In vitro and in vivo studies on the transport of PEGylated silica nanoparticles across the blood-brain barrier. ACS Appl Mater Interf 6:2131-2136.
    • (2014) ACS Appl Mater Interf , vol.6 , pp. 2131-2136
    • Liu, D.1    Lin, B.2    Shao, W.3    Zhu, Z.4    Ji, T.5    Yang, C.6
  • 72
    • 84855726392 scopus 로고    scopus 로고
    • Pathological mechanisms of liver injury caused by continuous intraperitoneal injection of silica nanoparticles
    • Liu T, Li L, Fu C, Liu H, Chen D, Tang F. 2012. Pathological mechanisms of liver injury caused by continuous intraperitoneal injection of silica nanoparticles. Biomaterials 33:2399-2407.
    • (2012) Biomaterials , vol.33 , pp. 2399-2407
    • Liu, T.1    Li, L.2    Fu, C.3    Liu, H.4    Chen, D.5    Tang, F.6
  • 74
    • 33746255334 scopus 로고    scopus 로고
    • Titanium dioxide (P25) produces reactive oxygen species in immortalized brain microglia (BV2): Implications for nanoparticle neurotoxicity
    • Long TC, Saleh N, Tilton RD, Lowry GV, Veronesi B. 2006. Titanium dioxide (P25) produces reactive oxygen species in immortalized brain microglia (BV2): Implications for nanoparticle neurotoxicity. Environ Sci Technol 40:4346-4352.
    • (2006) Environ Sci Technol , vol.40 , pp. 4346-4352
    • Long, T.C.1    Saleh, N.2    Tilton, R.D.3    Lowry, G.V.4    Veronesi, B.5
  • 75
    • 77949903006 scopus 로고    scopus 로고
    • Neurologic Wilson's disease
    • Lorincz MT. 2010. Neurologic Wilson's disease. Ann N Y Acad Sci 1184:173-187.
    • (2010) Ann N Y Acad Sci , vol.1184 , pp. 173-187
    • Lorincz, M.T.1
  • 80
    • 84885725586 scopus 로고    scopus 로고
    • Inhibitory effects of multiwall carbon nanotubes with high iron impurity on viability and neuronal differentiation in cultured PC12 cells
    • Meng L, Jiang A, Chen R, Li CZ, Wang L, Qu Y, Wang P, Zhao Y, Chen C. 2013. Inhibitory effects of multiwall carbon nanotubes with high iron impurity on viability and neuronal differentiation in cultured PC12 cells. Toxicology 313:49-58.
    • (2013) Toxicology , vol.313 , pp. 49-58
    • Meng, L.1    Jiang, A.2    Chen, R.3    Li, C.Z.4    Wang, L.5    Qu, Y.6    Wang, P.7    Zhao, Y.8    Chen, C.9
  • 82
    • 67649185049 scopus 로고    scopus 로고
    • Genetics, environmental factors and the emerging role of epigenetics in neurodegenerative diseases
    • Migliore L, Coppedè F. 2009. Genetics, environmental factors and the emerging role of epigenetics in neurodegenerative diseases. Mutat Res 667:82-97.
    • (2009) Mutat Res , vol.667 , pp. 82-97
    • Migliore, L.1    Coppedè, F.2
  • 83
    • 79952994380 scopus 로고    scopus 로고
    • Development and evaluation of polymer nanoparticles for oral delivery of estradiol to rat brain in a model of Alzheimer's pathology
    • Mittal G, Carswell H, Brett R, Currie S, Kumar MN. 2011. Development and evaluation of polymer nanoparticles for oral delivery of estradiol to rat brain in a model of Alzheimer's pathology. J Control Release 150:220-228.
    • (2011) J Control Release , vol.150 , pp. 220-228
    • Mittal, G.1    Carswell, H.2    Brett, R.3    Currie, S.4    Kumar, M.N.5
  • 85
    • 77949884839 scopus 로고    scopus 로고
    • Advances in the treatment of neurodegenerative disorders employing nanotechnology
    • Modi G, Pillay V, Choonara YE. 2010. Advances in the treatment of neurodegenerative disorders employing nanotechnology. Ann N Y Acad Sci 1184:154-172.
    • (2010) Ann N Y Acad Sci , vol.1184 , pp. 154-172
    • Modi, G.1    Pillay, V.2    Choonara, Y.E.3
  • 88
    • 84864582026 scopus 로고    scopus 로고
    • Signal enhancement in antibody microarrays using quantum dots nanocrystals: Application to potential Alzheimer's disease biomarker screening
    • Morales-Narváez E, Montón H, Fomicheva A, Merkoçi A. 2012. Signal enhancement in antibody microarrays using quantum dots nanocrystals: Application to potential Alzheimer's disease biomarker screening. Anal Chem 84:6821-6827.
    • (2012) Anal Chem , vol.84 , pp. 6821-6827
    • Morales-Narváez, E.1    Montón, H.2    Fomicheva, A.3    Merkoçi, A.4
  • 93
    • 84866979311 scopus 로고    scopus 로고
    • Size dependent aqueous dispersibility of carboxylated multiwall carbon nanotubes
    • Ntim SA, Sae-Khow O, Desai C, Witzmann FA, Mitra S. 2012. Size dependent aqueous dispersibility of carboxylated multiwall carbon nanotubes. J Environ Monit 14:2772-2779.
    • (2012) J Environ Monit , vol.14 , pp. 2772-2779
    • Ntim, S.A.1    Sae-Khow, O.2    Desai, C.3    Witzmann, F.A.4    Mitra, S.5
  • 95
    • 84893742806 scopus 로고    scopus 로고
    • Nanocarrier-based approaches for treatment and detection of Alzheimer's disease
    • Oesterling BM, Gulati A, Joshi MD. 2014. Nanocarrier-based approaches for treatment and detection of Alzheimer's disease. J Nanosci Nanotechnol 14:137-156.
    • (2014) J Nanosci Nanotechnol , vol.14 , pp. 137-156
    • Oesterling, B.M.1    Gulati, A.2    Joshi, M.D.3
  • 97
    • 84876059352 scopus 로고    scopus 로고
    • Screening of different metal oxide nanoparticles reveals selective toxicity and inflammatory potential of silica nanoparticles in lung epithelial cells and macrophages
    • Panas A, Marquardt C, Nalcaci O, Bockhorn H, Baumann W, Paur HR, Mülhopt S, Diabaté S, Weiss C. 2013. Screening of different metal oxide nanoparticles reveals selective toxicity and inflammatory potential of silica nanoparticles in lung epithelial cells and macrophages. Nanotoxicology 7:259-273.
    • (2013) Nanotoxicology , vol.7 , pp. 259-273
    • Panas, A.1    Marquardt, C.2    Nalcaci, O.3    Bockhorn, H.4    Baumann, W.5    Paur, H.R.6    Mülhopt, S.7    Diabaté, S.8    Weiss, C.9
  • 98
    • 56549119606 scopus 로고    scopus 로고
    • Silver or silver nanoparticles: A hazardous threat to the environment and human health?
    • Panyala NR, Peña-Méndez EM, Havel J. 2008. Silver or silver nanoparticles: A hazardous threat to the environment and human health?. J Appl Biomed 6:117-129.
    • (2008) J Appl Biomed , vol.6 , pp. 117-129
    • Panyala, N.R.1    Peña-Méndez, E.M.2    Havel, J.3
  • 99
    • 57649243749 scopus 로고    scopus 로고
    • Oxidative stress and pro-inflammatory responses induced by silica nanoparticles in vivo and in vitro
    • Park EJ, Park K. 2009. Oxidative stress and pro-inflammatory responses induced by silica nanoparticles in vivo and in vitro. Toxicol Lett 184:18-25.
    • (2009) Toxicol Lett , vol.184 , pp. 18-25
    • Park, E.J.1    Park, K.2
  • 101
    • 84964240602 scopus 로고    scopus 로고
    • Uptake and metabolism of iron oxide nanoparticles in brain cells
    • Petters C, Irrsack E, Koch M, Dringen R. 2014. Uptake and metabolism of iron oxide nanoparticles in brain cells. Neurochem Res 39:1648-1660.
    • (2014) Neurochem Res , vol.39 , pp. 1648-1660
    • Petters, C.1    Irrsack, E.2    Koch, M.3    Dringen, R.4
  • 104
    • 84860390586 scopus 로고    scopus 로고
    • Influence of liberated silver from silver nanoparticles on nitrification inhibition of Nitrosomonas europaea
    • Radniecki TS, Stankus DP, Neigh A, Nason JA, Semprini L. 2011. Influence of liberated silver from silver nanoparticles on nitrification inhibition of Nitrosomonas europaea. Chemosphere 85:43-49.
    • (2011) Chemosphere , vol.85 , pp. 43-49
    • Radniecki, T.S.1    Stankus, D.P.2    Neigh, A.3    Nason, J.A.4    Semprini, L.5
  • 106
    • 84980053612 scopus 로고    scopus 로고
    • Pathways to neurodegeneration: Mechanistic insights from GWAS in Alzheimer's disease, Parkinson's disease, and related disorders
    • Ramanan VK, Saykin AJ. 2013. Pathways to neurodegeneration: Mechanistic insights from GWAS in Alzheimer's disease, Parkinson's disease, and related disorders. Am J Neurodegener Dis 2:145-175.
    • (2013) Am J Neurodegener Dis , vol.2 , pp. 145-175
    • Ramanan, V.K.1    Saykin, A.J.2
  • 107
    • 80051728609 scopus 로고    scopus 로고
    • Molecular biology of the blood-brain and the blood-cerebrospinal fluid barriers: Similarities and differences
    • Redzic Z. 2011. Molecular biology of the blood-brain and the blood-cerebrospinal fluid barriers: Similarities and differences. Fluids Barriers CNS 8:3.
    • (2011) Fluids Barriers CNS , vol.8 , pp. 3
    • Redzic, Z.1
  • 109
    • 79953141030 scopus 로고    scopus 로고
    • Are commercially available nanoparticles safe when applied to the skin?
    • Robertson TA, Sanchez WY, Roberts MS. 2010. Are commercially available nanoparticles safe when applied to the skin? J Biomed Nanotechnol 6:452-468.
    • (2010) J Biomed Nanotechnol , vol.6 , pp. 452-468
    • Robertson, T.A.1    Sanchez, W.Y.2    Roberts, M.S.3
  • 110
    • 84887922844 scopus 로고    scopus 로고
    • Targeted drug delivery across the blood brain barrier in Alzheimer's disease
    • Rocha S. 2013. Targeted drug delivery across the blood brain barrier in Alzheimer's disease. Curr Pharm Des 19:6635-6646.
    • (2013) Curr Pharm Des , vol.19 , pp. 6635-6646
    • Rocha, S.1
  • 113
    • 84859617027 scopus 로고    scopus 로고
    • Manufactured and airborne nanoparticle cardiopulmonary interactions: A review of mechanisms and the possible contribution of mast cells
    • Shannahan JH, Kodavanti UP, Brown JM. 2012. Manufactured and airborne nanoparticle cardiopulmonary interactions: A review of mechanisms and the possible contribution of mast cells. Inhal Toxicol 24:320-339.
    • (2012) Inhal Toxicol , vol.24 , pp. 320-339
    • Shannahan, J.H.1    Kodavanti, U.P.2    Brown, J.M.3
  • 114
    • 34447628891 scopus 로고    scopus 로고
    • Nanoparticles aggravate heat stress induced cognitive deficits, blood-brain barrier disruption, edema formation and brain pathology
    • Sharma HS, Sharma A. 2007. Nanoparticles aggravate heat stress induced cognitive deficits, blood-brain barrier disruption, edema formation and brain pathology. Prog Brain Res 162:245-273.
    • (2007) Prog Brain Res , vol.162 , pp. 245-273
    • Sharma, H.S.1    Sharma, A.2
  • 115
    • 68249161469 scopus 로고    scopus 로고
    • Influence of engineered nanoparticles from metals on the blood-brain barrier permeability, cerebral blood flow, brain edema and neurotoxicity. An experimental study in the rat and mice using biochemical and morphological approaches
    • Sharma HS, Ali SF, Hussain SM, Schlager JJ, Sharma A. 2009. Influence of engineered nanoparticles from metals on the blood-brain barrier permeability, cerebral blood flow, brain edema and neurotoxicity. An experimental study in the rat and mice using biochemical and morphological approaches. J Nanosci Nanotechnol 9:5055-5072.
    • (2009) J Nanosci Nanotechnol , vol.9 , pp. 5055-5072
    • Sharma, H.S.1    Ali, S.F.2    Hussain, S.M.3    Schlager, J.J.4    Sharma, A.5
  • 116
    • 78649361273 scopus 로고    scopus 로고
    • Influence of nanoparticles on blood-brain barrier permeability and brain edema formation in rats
    • Sharma HS, Hussain S, Schlager J, Ali SF, Sharma A. 2010. Influence of nanoparticles on blood-brain barrier permeability and brain edema formation in rats. Acta Neurochir Suppl 106:359-364.
    • (2010) Acta Neurochir Suppl , vol.106 , pp. 359-364
    • Sharma, H.S.1    Hussain, S.2    Schlager, J.3    Ali, S.F.4    Sharma, A.5
  • 117
    • 84885200313 scopus 로고    scopus 로고
    • Exacerbation of brain pathology after partial restraint in hypertensive rats following SiO2 nanoparticles exposure at high ambient temperature
    • Sharma HS, Muresanu DF, Patnaik R, Sharma A. 2013a. Exacerbation of brain pathology after partial restraint in hypertensive rats following SiO2 nanoparticles exposure at high ambient temperature. Mol Neurobiol 48:368-379.
    • (2013) Mol Neurobiol , vol.48 , pp. 368-379
    • Sharma, H.S.1    Muresanu, D.F.2    Patnaik, R.3    Sharma, A.4
  • 118
    • 84885233952 scopus 로고    scopus 로고
    • Size- and age-dependent neurotoxicity of engineered metal nanoparticles in rats
    • Sharma A, Muresanu DF, Patnaik R, Sharma HS. 2013b. Size- and age-dependent neurotoxicity of engineered metal nanoparticles in rats. Mol Neurobiol 48:386-396.
    • (2013) Mol Neurobiol , vol.48 , pp. 386-396
    • Sharma, A.1    Muresanu, D.F.2    Patnaik, R.3    Sharma, H.S.4
  • 119
    • 84901939016 scopus 로고    scopus 로고
    • Effects of sub-acute exposure to TiO2, ZnO and Al2O3 nanoparticles on oxidative stress and histological changes in mouse liver and brain
    • Shrivastava R, Raza S, Yadav A, Kushwaha P, Flora SJ. 2014. Effects of sub-acute exposure to TiO2, ZnO and Al2O3 nanoparticles on oxidative stress and histological changes in mouse liver and brain. Drug Chem Toxicol 37:336-347.
    • (2014) Drug Chem Toxicol , vol.37 , pp. 336-347
    • Shrivastava, R.1    Raza, S.2    Yadav, A.3    Kushwaha, P.4    Flora, S.J.5
  • 120
    • 84864435661 scopus 로고    scopus 로고
    • Cellular uptake, intracellular trafficking and cytotoxicity of silver nanoparticles
    • Singh RP, Ramarao P. 2010. Cellular uptake, intracellular trafficking and cytotoxicity of silver nanoparticles. Toxicol Lett 213:249-259.
    • (2010) Toxicol Lett , vol.213 , pp. 249-259
    • Singh, R.P.1    Ramarao, P.2
  • 126
    • 79955695259 scopus 로고    scopus 로고
    • Molecular insights into Parkinson's disease
    • Thomas B, Beal MF. 2011. Molecular insights into Parkinson's disease. F1000 Med Rep 3:7.
    • (2011) F1000 Med Rep , vol.3 , pp. 7
    • Thomas, B.1    Beal, M.F.2
  • 127
    • 0035211681 scopus 로고    scopus 로고
    • Astroglia as metal depots: Molecular mechanisms for metal accumulation, storage and release
    • Tiffany-Castiglioni E, Qian Y. 2001. Astroglia as metal depots: Molecular mechanisms for metal accumulation, storage and release. Neurotoxicology 22:577-592.
    • (2001) Neurotoxicology , vol.22 , pp. 577-592
    • Tiffany-Castiglioni, E.1    Qian, Y.2
  • 134
    • 84866045532 scopus 로고    scopus 로고
    • A review of mammalian toxicity of ZnO nanoparticles
    • Vandebriel RJ, De Jong WH. 2012. A review of mammalian toxicity of ZnO nanoparticles. Nanotechnol Sci Appl 5:61-71.
    • (2012) Nanotechnol Sci Appl , vol.5 , pp. 61-71
    • Vandebriel, R.J.1    De Jong, W.H.2
  • 136
    • 84887043259 scopus 로고    scopus 로고
    • Role of stress granules and RNA-binding proteins in neurodegeneration: A mini-review
    • Vanderweyde T, Youmans K, Liu-Yesucevitz L, Wolozin B. 2013. Role of stress granules and RNA-binding proteins in neurodegeneration: A mini-review. Gerontology 59:524-533.
    • (2013) Gerontology , vol.59 , pp. 524-533
    • Vanderweyde, T.1    Youmans, K.2    Liu-Yesucevitz, L.3    Wolozin, B.4
  • 138
  • 139
    • 56049102066 scopus 로고    scopus 로고
    • Time-dependent translocation and potential impairment on central nervous system by intranasally instilled TiO(2) nanoparticles
    • Wang J, Liu Y, Jiao F, Lao F, Li W, Gu Y, Li Y, Ge C, Zhou G, Li B, et al. 2008. Time-dependent translocation and potential impairment on central nervous system by intranasally instilled TiO(2) nanoparticles. Toxicology 254:82-90.
    • (2008) Toxicology , vol.254 , pp. 82-90
    • Wang, J.1    Liu, Y.2    Jiao, F.3    Lao, F.4    Li, W.5    Gu, Y.6    Li, Y.7    Ge, C.8    Zhou, G.9    Li, B.10
  • 141
    • 82655182015 scopus 로고    scopus 로고
    • Oxidative mechanisms contribute to nanosize silican dioxide-induced developmental neurotoxicity in PC12 cells
    • Wang F, Jiao C, Liu J, Yuan H, Lan M, Gao F. 2011a. Oxidative mechanisms contribute to nanosize silican dioxide-induced developmental neurotoxicity in PC12 cells. Toxicol In Vitro 25:1548-1556.
    • (2011) Toxicol In Vitro , vol.25 , pp. 1548-1556
    • Wang, F.1    Jiao, C.2    Liu, J.3    Yuan, H.4    Lan, M.5    Gao, F.6
  • 142
    • 78650517980 scopus 로고    scopus 로고
    • Cytotoxicity of single-walled carbon nanotubes on PC12 cells
    • Wang J, Sun P, Bao Y, Liu J, An L. 2011b. Cytotoxicity of single-walled carbon nanotubes on PC12 cells. Toxicol In Vitro 25:242-250.
    • (2011) Toxicol In Vitro , vol.25 , pp. 242-250
    • Wang, J.1    Sun, P.2    Bao, Y.3    Liu, J.4    An, L.5
  • 143
    • 84855359265 scopus 로고    scopus 로고
    • Vitamin E renders protection to PC12 cells against oxidative damage and apoptosis induced by single-walled carbon nanotubes
    • Wang J, Sun P, Bao Y, Dou B, Song D, Li Y. 2012. Vitamin E renders protection to PC12 cells against oxidative damage and apoptosis induced by single-walled carbon nanotubes. Toxicol In Vitro 26:32-41.
    • (2012) Toxicol In Vitro , vol.26 , pp. 32-41
    • Wang, J.1    Sun, P.2    Bao, Y.3    Dou, B.4    Song, D.5    Li, Y.6
  • 144
    • 40849097322 scopus 로고    scopus 로고
    • Poly (n-butylcyanoacrylate) nanoparticles coated with polysorbate 80 for the targeted delivery of rivastigmine into the brain to treat Alzheimer's disease
    • Wilson B, Samanta MK, Santhi K, Kumar KP, Paramakrishnan N, Suresh B. 2008. Poly (n-butylcyanoacrylate) nanoparticles coated with polysorbate 80 for the targeted delivery of rivastigmine into the brain to treat Alzheimer's disease. Brain Res 1200:159-168.
    • (2008) Brain Res , vol.1200 , pp. 159-168
    • Wilson, B.1    Samanta, M.K.2    Santhi, K.3    Kumar, K.P.4    Paramakrishnan, N.5    Suresh, B.6
  • 145
    • 0036627211 scopus 로고    scopus 로고
    • Tight junctions of the blood-brain barrier: Development, composition and regulation
    • Wolburg H, Lippoldt A. 2002. Tight junctions of the blood-brain barrier: Development, composition and regulation. Vascul Pharmacol 38:323-337.
    • (2002) Vascul Pharmacol , vol.38 , pp. 323-337
    • Wolburg, H.1    Lippoldt, A.2
  • 146
    • 78650516786 scopus 로고    scopus 로고
    • Involvement of JNK and P53 activation in G2/M cell cycle arrest and apoptosis induced by titanium dioxide nanoparticles in neuron cells
    • Wu J, Sun J, Xue Y. 2010. Involvement of JNK and P53 activation in G2/M cell cycle arrest and apoptosis induced by titanium dioxide nanoparticles in neuron cells. Toxicol Lett 199:269-276.
    • (2010) Toxicol Lett , vol.199 , pp. 269-276
    • Wu, J.1    Sun, J.2    Xue, Y.3
  • 147
    • 79959790434 scopus 로고    scopus 로고
    • Neurotoxicity of silica nanoparticles: Brain localization and dopaminergic neurons damage pathways
    • Wu J, Wang C, Sun J, Xue Y. 2011. Neurotoxicity of silica nanoparticles: Brain localization and dopaminergic neurons damage pathways. ACS Nano 5:4476-4489.
    • (2011) ACS Nano , vol.5 , pp. 4476-4489
    • Wu, J.1    Wang, C.2    Sun, J.3    Xue, Y.4
  • 148
    • 84872675495 scopus 로고    scopus 로고
    • Neurotoxic potential of iron oxide nanoparticles in the rat brain striatum and hippocampus
    • Wu J, Ding T, Sun J. 2013. Neurotoxic potential of iron oxide nanoparticles in the rat brain striatum and hippocampus. Neurotoxicology 34:243-253.
    • (2013) Neurotoxicology , vol.34 , pp. 243-253
    • Wu, J.1    Ding, T.2    Sun, J.3
  • 149
    • 84856474977 scopus 로고    scopus 로고
    • Effects of nanoparticle zinc oxide on spatial cognition and synaptic plasticity in mice with depressive-like behaviors
    • Xie Y, Wang Y, Zhang T, Ren G, Yang Z. 2012. Effects of nanoparticle zinc oxide on spatial cognition and synaptic plasticity in mice with depressive-like behaviors. J Biomed Sci 19:14.
    • (2012) J Biomed Sci , vol.19 , pp. 14
    • Xie, Y.1    Wang, Y.2    Zhang, T.3    Ren, G.4    Yang, Z.5
  • 150
    • 84879034634 scopus 로고    scopus 로고
    • Silver nanoparticles (AgNPs) cause degeneration of cytoskeleton and disrupt synaptic machinery of cultured cortical neurons
    • Xu F, Piett C, Farkas S, Qazzaz M, Syed NI. 2013. Silver nanoparticles (AgNPs) cause degeneration of cytoskeleton and disrupt synaptic machinery of cultured cortical neurons. Mol Brain 6:29.
    • (2013) Mol Brain , vol.6 , pp. 29
    • Xu, F.1    Piett, C.2    Farkas, S.3    Qazzaz, M.4    Syed, N.I.5
  • 151
    • 84866292862 scopus 로고    scopus 로고
    • Four types of inorganic nanoparticles stimulate the inflammatory reaction in brain microglia and damage neurons in vitro
    • Xue Y, Wu J, Sun J. 2012. Four types of inorganic nanoparticles stimulate the inflammatory reaction in brain microglia and damage neurons in vitro. Toxicol Lett 214:91-98.
    • (2012) Toxicol Lett , vol.214 , pp. 91-98
    • Xue, Y.1    Wu, J.2    Sun, J.3
  • 152
    • 77952678343 scopus 로고    scopus 로고
    • Pharmacological and toxicological target organelles and safe use of single-walled carbon nanotubes as drug carriers in treating Alzheimer disease
    • Yang Z, Zhang Y, Yang Y, Sun L, Han D, Li H, Wang C. 2010. Pharmacological and toxicological target organelles and safe use of single-walled carbon nanotubes as drug carriers in treating Alzheimer disease. Nanomedicine 6:427-441.
    • (2010) Nanomedicine , vol.6 , pp. 427-441
    • Yang, Z.1    Zhang, Y.2    Yang, Y.3    Sun, L.4    Han, D.5    Li, H.6    Wang, C.7
  • 153
    • 79952670561 scopus 로고    scopus 로고
    • Detection of amyloid plaques targeted by USPIO-Aβ1-42 in Alzheimer's disease transgenic mice using magnetic resonance microimaging
    • Yang J, Wadghiri YZ, Hoang DM, Tsui W, Sun Y, Chung E, Li Y, Wang A, de Leon M, Wisniewski T. 2011. Detection of amyloid plaques targeted by USPIO-Aβ1-42 in Alzheimer's disease transgenic mice using magnetic resonance microimaging. Neuroimage 55:1600-1609.
    • (2011) Neuroimage , vol.55 , pp. 1600-1609
    • Yang, J.1    Wadghiri, Y.Z.2    Hoang, D.M.3    Tsui, W.4    Sun, Y.5    Chung, E.6    Li, Y.7    Wang, A.8    de Leon, M.9    Wisniewski, T.10
  • 154
    • 84862908624 scopus 로고    scopus 로고
    • Mechanism of silver nanoparticle toxicity is dependent on dissolved silver and surface coating in Caenorhabditis elegans
    • Yang X, Gondikas AP, Marinakos SM, Auffan M, Liu J, Hsu-Kim H, Meyer JN. 2012. Mechanism of silver nanoparticle toxicity is dependent on dissolved silver and surface coating in Caenorhabditis elegans. Environ Sci Technol 46:1119-1127.
    • (2012) Environ Sci Technol , vol.46 , pp. 1119-1127
    • Yang, X.1    Gondikas, A.P.2    Marinakos, S.M.3    Auffan, M.4    Liu, J.5    Hsu-Kim, H.6    Meyer, J.N.7
  • 155
    • 84903694976 scopus 로고    scopus 로고
    • Uptake of silica nanoparticles: Neurotoxicity and Alzheimer-like pathology in human SK-N-SH and mouse neuro2a neuroblastoma cells
    • Yang X, He C, Li J, Chen H, Ma Q, Sui X, Tian S, Ying M, Zhang Q, Luo Y, et al. 2014. Uptake of silica nanoparticles: Neurotoxicity and Alzheimer-like pathology in human SK-N-SH and mouse neuro2a neuroblastoma cells. Toxicol Lett 229:240-249.
    • (2014) Toxicol Lett , vol.229 , pp. 240-249
    • Yang, X.1    He, C.2    Li, J.3    Chen, H.4    Ma, Q.5    Sui, X.6    Tian, S.7    Ying, M.8    Zhang, Q.9    Luo, Y.10
  • 156
    • 84866063329 scopus 로고    scopus 로고
    • Cytotoxic effects of ZnO hierarchical architectures on RSC96 Schwann cells
    • Yin Y, Lin Q, Sun H, Chen D, Wu Q, Chen X, Li S. 2012. Cytotoxic effects of ZnO hierarchical architectures on RSC96 Schwann cells. Nanoscale Res Lett 7:439.
    • (2012) Nanoscale Res Lett , vol.7 , pp. 439
    • Yin, Y.1    Lin, Q.2    Sun, H.3    Chen, D.4    Wu, Q.5    Chen, X.6    Li, S.7
  • 157
    • 84862650655 scopus 로고    scopus 로고
    • Fe3O4-PEI-RITC magnetic nanoparticles with imaging and gene transfer capability: Development of a tool for neural cell transplantation therapies
    • Yiu HH, Pickard MR, Olariu CI, Williams SR, Chari DM, Rosseinsky MJ. 2012. Fe3O4-PEI-RITC magnetic nanoparticles with imaging and gene transfer capability: Development of a tool for neural cell transplantation therapies. Pharm Res 29:1328-1343.
    • (2012) Pharm Res , vol.29 , pp. 1328-1343
    • Yiu, H.H.1    Pickard, M.R.2    Olariu, C.I.3    Williams, S.R.4    Chari, D.M.5    Rosseinsky, M.J.6
  • 160
    • 84863298377 scopus 로고    scopus 로고
    • ZnO, TiO(2), SiO(2,) and Al(2)O(3) nanoparticles-induced toxic effects on human fetal lung fibroblasts
    • Zhang XQ, Yin LH, Tang M, Pu YP. 2011c. ZnO, TiO(2), SiO(2, ) and Al(2)O(3) nanoparticles-induced toxic effects on human fetal lung fibroblasts. Biomed Environ Sci 24:661-669.
    • (2011) Biomed Environ Sci , vol.24 , pp. 661-669
    • Zhang, X.Q.1    Yin, L.H.2    Tang, M.3    Pu, Y.P.4
  • 161
    • 84902507769 scopus 로고    scopus 로고
    • Photosensitive fluorescent dye contributes to phototoxicity and inflammatory responses of dye-doped silica NPs in cells and mice
    • Zhao Y, Ye Y, Zhou X, Chen J, Jin Y, Hanson A, Zhao JX, Wu M. 2014. Photosensitive fluorescent dye contributes to phototoxicity and inflammatory responses of dye-doped silica NPs in cells and mice. Theranostics 4:445-459.
    • (2014) Theranostics , vol.4 , pp. 445-459
    • Zhao, Y.1    Ye, Y.2    Zhou, X.3    Chen, J.4    Jin, Y.5    Hanson, A.6    Zhao, J.X.7    Wu, M.8
  • 162
    • 84893228084 scopus 로고    scopus 로고
    • Synthesis of superparamagnetic iron oxide nanoparticles coated with a DDNP-carboxyl derivative for in vitro magnetic resonance imaging of Alzheimer's disease
    • Zhou J, Fa H, Yin W, Zhang J, Hou C, Huo D, Zhang D, Zhang H. 2014. Synthesis of superparamagnetic iron oxide nanoparticles coated with a DDNP-carboxyl derivative for in vitro magnetic resonance imaging of Alzheimer's disease. Mater Sci Eng C Mater Biol Appl 37:348-355.
    • (2014) Mater Sci Eng C Mater Biol Appl , vol.37 , pp. 348-355
    • Zhou, J.1    Fa, H.2    Yin, W.3    Zhang, J.4    Hou, C.5    Huo, D.6    Zhang, D.7    Zhang, H.8
  • 163
    • 84890283664 scopus 로고    scopus 로고
    • The role of the glutamatergic NMDA receptor in nanosilver-evoked neurotoxicity in primary cultures of cerebellar granule cells
    • Ziemińska E, Stafiej A, Struzyńska L. 2014. The role of the glutamatergic NMDA receptor in nanosilver-evoked neurotoxicity in primary cultures of cerebellar granule cells. Toxicology 315:38-48.
    • (2014) Toxicology , vol.315 , pp. 38-48
    • Ziemińska, E.1    Stafiej, A.2    Struzyńska, L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.