Uptake of silica nanoparticles: Neurotoxicity and Alzheimer-like pathology in human SK-N-SH and mouse neuro2a neuroblastoma cells

Toxicology Letters

Volumn 229, Issue 1, 2014, Pages 240-249

  Yang, Xifei ^a   He, Chun'e ^a   Li, Jie ^a,d   Chen, Hongbin ^a   Ma, Quan ^a   Sui, Xiaojing ^a   Tian, Shengli ^b   Ying, Ming ^b   Zhang, Qian ^a   Luo, Yougen ^c   Zhuang, Zhixiong ^a   Liu, Jianjun ^a  

^a SHENZHEN CENTER FOR DISEASE CONTROL AND PREVENTION   (China)

^b SHENZHEN UNIVERSITY   (China)

^c JINGGANGSHAN UNIVERSITY   (China)

^d SOUTHERN MEDICAL UNIVERSITY   (China)

Author keywords

Alzheimer's disease (AD); Neurotoxicity; Silica nanoparticles (SiNPs); Tau; amyloid (A )

Indexed keywords

AMYLOID BETA PROTEIN[1-42]; AMYLOID PRECURSOR PROTEIN; GLYCOGEN SYNTHASE KINASE 3BETA; MEMBRANE METALLOENDOPEPTIDASE; NANOPARTICLE; REACTIVE OXYGEN METABOLITE; SERINE; SILICON DIOXIDE; TAU PROTEIN;

ALZHEIMER DISEASE; ANIMAL CELL; APOPTOSIS; ARTICLE; CELL DENSITY; CELL STRUCTURE; CELL VIABILITY; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOPLASM; DENDRITE; DOWN REGULATION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; NEUROBLASTOMA CELL; NEUROTOXICITY; NONHUMAN; PHOSPHORYLATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; TRANSMISSION ELECTRON MICROSCOPY; UPREGULATION;

ALZHEIMER'S DISEASE (AD); NEUROTOXICITY; SILICA NANOPARTICLES (SINPS); TAU; Β AMYLOID (AΒ);

ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; ANIMALS; APOPTOSIS; BLOTTING, WESTERN; CELL LINE; CELL LINE, TUMOR; CELL SURVIVAL; FLUORESCENT ANTIBODY TECHNIQUE; GLYCOGEN SYNTHASE KINASE 3; HUMANS; MICE; MICROSCOPY, ELECTRON, TRANSMISSION; NANOPARTICLES; NEUROTOXICITY SYNDROMES; PHOSPHORYLATION; REACTIVE OXYGEN SPECIES; SILICON DIOXIDE; TAU PROTEINS;

EID: 84903694976     PISSN: 03784274     EISSN: 18793169     Source Type: Journal    
DOI: 10.1016/j.toxlet.2014.05.009     Document Type: Article

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