Silver nanoparticles (AgNPs) cause degeneration of cytoskeleton and disrupt synaptic machinery of cultured cortical neurons

Molecular Brain

Volumn 6, Issue 1, 2013, Pages

  Xu, Fenglian ^a   Piett, Cortt ^b   Farkas, Svetlana ^a   Qazzaz, Munir ^a,c   Syed, Naweed I ^a  

^a UNIVERSITY OF CALGARY   (Canada)

^b MOUNT ROYAL UNIVERSITY   (Canada)

^c BIRZEIT UNIVERSITY   (Palestine)

Author keywords

Cytoskeleton; Mitochondria; Rat cortical culture; Silver nanoparticles; Synaptic machinery; Toxicity

Indexed keywords

BETA TUBULIN; F ACTIN; POSTSYNAPTIC RECEPTOR DENSITY PROTEIN 95; SILVER NANOPARTICLE; SYNAPSE RECEPTOR; SYNAPTOPHYSIN; UNCLASSIFIED DRUG; ACTIN; CYTOSKELETON PROTEIN; GLIAL FIBRILLARY ACIDIC PROTEIN; METAL NANOPARTICLE; SILVER; TUBULIN;

ANIMAL CELL; ARTICLE; BRAIN CORTEX; CELL DEATH; CELL DEGENERATION; CELL FUNCTION; CELL STRUCTURE; CELL VIABILITY; CONFOCAL MICROSCOPY; CONTROLLED STUDY; FRONTAL CORTEX; GLIA CELL; IMMUNOCYTOCHEMISTRY; NERVE CELL CULTURE; NERVE CELL DIFFERENTIATION; NERVE FIBER GROWTH; NEUROTOXICITY; NONHUMAN; PARTICLE SIZE; PERIKARYON; PRIORITY JOURNAL; SYNAPSE; ANIMAL; CELL CULTURE; CELL SURVIVAL; CYTOSKELETON; DRUG EFFECTS; FLUORESCENCE; METABOLISM; MITOCHONDRION; NERVE CELL; NEURITE; PATHOLOGY; SPRAGUE DAWLEY RAT; SYNAPSE VESICLE; TOXICITY;

ANIMALIA; RATTUS;

ACTINS; ANIMALS; CELL SURVIVAL; CELLS, CULTURED; CEREBRAL CORTEX; CYTOSKELETAL PROTEINS; CYTOSKELETON; FLUORESCENCE; GLIAL FIBRILLARY ACIDIC PROTEIN; METAL NANOPARTICLES; MITOCHONDRIA; NEURITES; NEURONS; RATS, SPRAGUE-DAWLEY; SILVER; SYNAPSES; SYNAPTIC VESICLES; TUBULIN;

EID: 84879034634     PISSN: None     EISSN: 17566606     Source Type: Journal    
DOI: 10.1186/1756-6606-6-29     Document Type: Article

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