Oxidative mechanisms contribute to nanosize silican dioxide-induced developmental neurotoxicity in PC12 cells

Toxicology in Vitro

Volumn 25, Issue 8, 2011, Pages 1548-1556

  Wang, Fen ^a   Jiao, Changping ^a   Liu, Jianwen ^b   Yuan, Huihui ^a   Lan, Minbo ^a   Gao, Feng ^a  

^a EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

Apoptosis; Neurotoxicity; Oxidative stress; PC12 cells; Silica nanoparticles

Indexed keywords

FREE RADICAL; GLUTATHIONE; NANOPARTICLE; NERVE GROWTH FACTOR; REACTIVE OXYGEN METABOLITE; SILICAN DIOXIDE; THIOBARBITURIC ACID REACTIVE SUBSTANCE; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL CYCLE G1 PHASE; CELL DAMAGE; CELL DEATH; CELL MEMBRANE; CELL NUCLEUS; CELL POPULATION; CELL SHRINKAGE; CELL STRAIN; CELL STRESS; CELL VIABILITY; CELLULAR PARAMETERS; CONTROLLED STUDY; DEVELOPMENTAL DISORDER; DOSE TIME EFFECT RELATION; GROWTH INHIBITION; LIPID PEROXIDATION; NERVE FIBER GROWTH; NEUROTOXICITY; NONHUMAN; OXIDATIVE STRESS; PROTEIN DEPLETION; RAT;

ANIMALS; APOPTOSIS; CELL SURVIVAL; GLUTATHIONE; LIPID PEROXIDATION; MICROSCOPY, ELECTRON, TRANSMISSION; NANOPARTICLES; NERVE GROWTH FACTOR; NEURITES; OXIDATIVE STRESS; PC12 CELLS; RATS; REACTIVE OXYGEN SPECIES; SILICON DIOXIDE; THIOBARBITURIC ACID REACTIVE SUBSTANCES;

EID: 82655182015     PISSN: 08872333     EISSN: 18793177     Source Type: Journal    
DOI: 10.1016/j.tiv.2011.05.019     Document Type: Article

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