Involvement of JNK and P53 activation in G2/M cell cycle arrest and apoptosis induced by titanium dioxide nanoparticles in neuron cells

Toxicology Letters

Volumn 199, Issue 3, 2010, Pages 269-276

  Wu, Jie ^a   Sun, Jiao ^a   Xue, Yang ^a  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

Apoptosis; Cell cycle; Neurons; Oxidative stress; P53; Titanium dioxide nanoparticles

Indexed keywords

LACTATE DEHYDROGENASE; NANOPARTICLE; PROTEIN P53; REACTIVE OXYGEN METABOLITE; STRESS ACTIVATED PROTEIN KINASE; TITANIUM DIOXIDE;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL CYCLE ARREST; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL STRAIN; CELL VIABILITY; CONTROLLED STUDY; CRYSTAL STRUCTURE; CYTOTOXICITY; DOPAMINERGIC NERVE CELL; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; NEUROTOXICITY; NONHUMAN; OXIDATIVE STRESS; PARTICLE SIZE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

ANIMALS; APOPTOSIS; CELL DIVISION; DOSE-RESPONSE RELATIONSHIP, DRUG; G2 PHASE; JNK MITOGEN-ACTIVATED PROTEIN KINASES; NANOPARTICLES; NEURONS; OXIDATIVE STRESS; PARTICLE SIZE; PC12 CELLS; RATS; REACTIVE OXYGEN SPECIES; TITANIUM; TUMOR SUPPRESSOR PROTEIN P53;

EID: 78650516786     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxlet.2010.09.009     Document Type: Article

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