Targeting vascular amyloid in arterioles of alzheimer disease transgenic mice with amyloid β protein antibody-coated nanoparticles

Journal of Neuropathology and Experimental Neurology

Volumn 70, Issue 8, 2011, Pages 653-661

  Poduslo, Joseph F ^a   Hultman, Kristi L ^a   Curran, Geoffry L ^a   Preboske, Gregory M ^a   Chamberlain, Ryan ^b   Marjańska, Małgorzata ^b   Garwood, Michael ^b   Jack Jr , Clifford R ^a   Wengenack, Thomas M ^a  

^a MAYO CLINIC   (United States)

^b UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

Author keywords

Alzheimer disease; Cerebral amyloid angiopathy; Cerebrovascular amyloid; Confocal laser scanning microscopy; Immunotargeted nanoparticles; Magnetic resonance imaging

Indexed keywords

AMYLOID BETA PROTEIN ANTIBODY; AMYLOID BETA PROTEIN[1-42]; IMMUNOGLOBULIN G4; NANOPARTICLE; PHOSPHOLIPID;

ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERIOLE; ARTICLE; BRAIN HOMOGENATE; CAROTID ARTERY; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; ENDOTHELIUM CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; VASCULAR AMYLOIDOSIS;

ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; ANTIGENS, CD31; ARTERIOLES; DISEASE MODELS, ANIMAL; FERRIC COMPOUNDS; HUMANS; IMMUNOGLOBULIN G; MAGNETIC RESONANCE IMAGING; MICE; MICE, TRANSGENIC; MICROSCOPY, ELECTRON, TRANSMISSION; NANOPARTICLES; PEPTIDE FRAGMENTS; PLAQUE, AMYLOID; THIAZOLES;

EID: 79961022470     PISSN: 00223069     EISSN: 15546578     Source Type: Journal    
DOI: 10.1097/NEN.0b013e318225038c     Document Type: Article

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