Lactoferrin conjugated PEG-PLGA nanoparticles for brain delivery: Preparation, characterization and efficacy in Parkinsons disease

International Journal of Pharmaceutics

Volumn 415, Issue 1-2, 2011, Pages 273-283

  Hu, Kaili ^a,b   Shi, Yanbin ^c   Jiang, Wenming ^d   Han, Jiaying ^a   Huang, Shixian ^a   Jiang, Xinguo ^a  

^a FUDAN UNIVERSITY   (China)

^b SHANGHAI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

^c LANZHOU UNIVERSITY   (China)

^d SHANGHAI INSTITUTE FOR FOOD AND DRUG CONTROL   (China)

Author keywords

Blood brain barrier (BBB); Lactoferrin; Parkinson's disease; PLGA nanoparticles; Urocortin

Indexed keywords

CD68 ANTIGEN; CLATHRIN; COUMARIN; FLUORESCENT DYE; LACTOFERRIN; MACROGOL; MALEIMIDE; NANOPARTICLE; OXIDOPAMINE; POLYGLYCOLIDE; UROCORTIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL VIABILITY; DRUG DELIVERY SYSTEM; DRUG DISTRIBUTION; DRUG EFFICACY; DRUG UPTAKE; ENDOCYTOSIS; ENZYME LINKED IMMUNOSORBENT ASSAY; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; NONHUMAN; PARKINSON DISEASE; PRIORITY JOURNAL; RAT; TISSUE DISTRIBUTION;

ANIMALS; ANTIPARKINSON AGENTS; BEHAVIOR, ANIMAL; BRAIN; CELL LINE; CELL SURVIVAL; DRUG CARRIERS; DRUG COMPOUNDING; LACTOFERRIN; MICE; MICE, INBRED BALB C; MICROSCOPY, ELECTRON, TRANSMISSION; NANOPARTICLES; PARKINSON DISEASE; PARTICLE SIZE; POLYETHYLENE GLYCOLS; POLYGLACTIN 910; RATS; RATS, SPRAGUE-DAWLEY; SURFACE PROPERTIES; TISSUE DISTRIBUTION; UROCORTINS;

EID: 79960167888     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2011.05.062     Document Type: Article

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