Cognitive impairment in rats induced by nano-CuO and its possible mechanisms

Toxicology Letters

Volumn 213, Issue 2, 2012, Pages 220-227

  An, Lei ^a   Liu, Shichang ^a   Yang, Zhuo ^a   Zhang, Tao ^a  

^a NANKAI UNIVERSITY   (China)

Author keywords

Apoptosis; Long term potentiation; Nano CuO; Rats; ROS; Spatial cognition

Indexed keywords

4 HYDROXYNONENAL; CASPASE 3; COPPER OXIDE; GLUTATHIONE PEROXIDASE; MALONALDEHYDE; NANOPARTICLE; REACTIVE OXYGEN METABOLITE; SUPEROXIDE DISMUTASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; BLOOD BRAIN BARRIER; BRAIN ELECTROPHYSIOLOGY; BRAIN LEVEL; COGNITIVE DEFECT; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; HIPPOCAMPAL CA1 REGION; HISTOPATHOLOGY; IN VIVO STUDY; LEARNING DISORDER; LONG TERM POTENTIATION; MALE; MAZE TEST; MEMORY DISORDER; NERVE CELL PLASTICITY; NEUROTOXICITY; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT;

ALDEHYDES; ANIMALS; COGNITION; COGNITION DISORDERS; COPPER; GLUTATHIONE PEROXIDASE; HIPPOCAMPUS; HISTOCYTOCHEMISTRY; LONG-TERM POTENTIATION; MALE; MALONDIALDEHYDE; MAZE LEARNING; METAL NANOPARTICLES; OXIDATIVE STRESS; RANDOM ALLOCATION; RATS; RATS, WISTAR; SUPEROXIDE DISMUTASE;

ANIMALIA; RATTUS;

EID: 84864457874     PISSN: 03784274     EISSN: 18793169     Source Type: Journal    
DOI: 10.1016/j.toxlet.2012.07.007     Document Type: Article

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