Inflammation and gene expression in the rat lung after instillation of silica nanoparticles: Effect of size, dispersion medium and particle surface charge

Toxicology Letters

Volumn 224, Issue 1, 2014, Pages 147-156

  Brown, David M ^a   Kanase, Nilesh ^a   Gaiser, Birgit ^a   Johnston, Helinor ^a   Stone, Vicki ^a  

^a HERIOT WATT UNIVERSITY   (United Kingdom)

Author keywords

Gene expression; In vivo; Inflammation; Silica nanoparticles

Indexed keywords

ALBUMIN; BOVINE SERUM ALBUMIN; NANOPARTICLE; SILICON DIOXIDE; SODIUM CHLORIDE; TRANSCRIPTION FACTOR NRF2;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; DISPERSION; GENE EXPRESSION; IMMUNOHISTOCHEMISTRY; INFLAMMATION; LUNG; LUNG LAVAGE; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; RAT; SURFACE CHARGE;

ANIMALS; CELL MOVEMENT; GENE EXPRESSION; INFLAMMATION; LUNG; MALE; NANOPARTICLES; NEUTROPHILS; NF-E2-RELATED FACTOR 2; PHAGOCYTOSIS; RATS; RATS, SPRAGUE-DAWLEY; SILICON DIOXIDE; SURFACE PROPERTIES;

EID: 84887686466     PISSN: 03784274     EISSN: 18793169     Source Type: Journal    
DOI: 10.1016/j.toxlet.2013.10.019     Document Type: Article

References (35)

1. Bakshi M.S., Zhao L., Smith R., Possmayer F., Petersen N.O. Metal nanoparticle pollutants interfere with pulmonary surfactant function in vitro. Biophys. J. 2008, 94:855-868.
2. Balbus J.M., Maynard A.D., Colvin V.L., Castranove V., Daston G.P., Denison R.A., et al. Meeting report: hazard assessment for NPs - report from an interdisciplinary workshop. Environ. Health Perspect. 2007, 115(11):1654-1659.
3. Bartlett J.A., Albertolle M.E., Wohlford-Lenane C., Pezzulo A.A., Zabner J., Richard K., Niles R.K., Fisher S.J., McCray P.B., Williams K.E. Protein composition of bronchoalveolar lavage fluid and airway surface liquid from newborn pigs. Am. J. Physiol.: Lung Cell. Mol. Physiol. 2013, 10:1152.
4. Baughman R.P., Mangels D.J., Strohofer S., Corser B.C. Enhancement of macrophage and monocyte cytotoxicity by the surface active material of lung lining fluid. J. Lab. Clin. Med. 1987, 109(6):692-697.
5. Bihari P., Vippola M., Schultes S., Praetner M., Khandoga A.G., Reichel C.A., et al. Optimized dispersion of nanoparticles for biological in vitro and in vivo studies. Part. Fibre Toxicol. 2008, 5:14.
6. Borm P.J., Robbins D., Haubold S., Kuhlbusch T., Fissan H., Donaldson K., et al. The potential risks of nanomaterials: a review carried out for ECETOC. Part. Fibre Toxicol. 2006, 3:11.
7. Brown D.M., Stone V., Findlay P., MacNee W., Donaldson K. Increased inflammation and intracellular calcium caused by ultrafine carbon black is independent of transition metals or other soluble components. Occup. Environ. Med. 2000, 57(10):685-691.
8. Brown D.M., Wilson M.R., MacNee W., Stone V., Donaldson K. Size-dependent proinflammatory effects of ultrafine polystyrene particles: a role for surface area and oxidative stress in the enhanced activity of ultrafines. Toxicol. Appl. Pharmacol. 2001, 175(3):191-199.
9. Brown D.M., Kinloch I.A., Bangert U., Windle A.H., Walter D.M., Walker G.S., Scotchford C.A., Donaldson K., Stone V. An in vitro study of the potential of carbon nanotubes and nanofibres to induce inflammatory mediators and frustrated phagocytosis. Carbon 2007, 45:1743-1756.
10. Brown D.M., Dickson C., Duncan P., Al-Attili F., Stone V. Interaction between NPs and cytokine proteins: impact on protein and particle functionality. Nanotechnology 2010, 21:215104.
11. Chung T.H., Wu S.H., Yao M., Lu C.W., Lin Y.S., Hung Y., et al. The effect of surface charge on the uptake and biological function of mesoporous silica nanoparticles in 3T3-L1 cells and human mesenchymal stem cells. Biomaterials 2007, 28:2959-2966.
12. Donaldson K., Stone V., Gilmour P.S., Brown D.M., MacNee W. Ultrafine particles: mechanisms of lung injury. Philos. Trans. R. Soc. Lond. A 2000, 358:2741-2748.
13. Duffin R., Tran L., Brown D., Stone V., Donaldson K. Proinflammogenic effects of low-toxicity and metal nanoparticles in vivo and in vitro: highlighting the role of particle surface area and surface reactivity. Inhal. Toxicol. 2007, 19(10):849-856.
14. Gao X., Cui Y., Levenson R.M., Chung L.W.K., Nie S. In vivo cancer targeting and imaging with semiconductor quantum dots. Nat. Biotechnol. 2004, 22:969-976.
15. He X., Zhang H., Ma Y., Bai W., Zhang Z., Lu K., Ding Y., Zhao Y., Chai Z. Lung deposition and extrapulmonary translocation of nano-ceria after intratracheal instillation. Nanotechnology 2010, 21:285103.
16. Ishii H., Hayashi S., Hogg J.C., Fujii T., Goto Y., Sakamoto N., et al. Alveolar macrophage-epithelial cell interaction following exposure to atmospheric particles induces the release of mediators involved in monocyte mobilization and recruitment. Respir. Res. 2005, 6:87.
17. Iyer R., Hamilton R.F., Li L., Holian A. Silica-induced apoptosis mediated via scavenger receptor in human alveolar macrophages. Toxicol. Appl. Pharmacol. 1996, 141(1):84-92.
18. Jani P.U., Halbert G.W., Langridge J., Florence A.T. Nanoparticle uptake by the rat gastrointestinal mucosa: quantitation and particle size dependency. J. Pharm. Pharmacol. 1990, 42:821.
19. Kaspar J.W., Niture S.K., Jaiswal A.K. Nrf2:INrf2 (Keap1) signaling in oxidative stress. Free Radic. Biol. Med. 2009, 47(9):1304-1309.
20. Kaewamatawong T., Shimada A., Okajima M., Inoue H., Morita T., Inoue K., Takano H. Acute and subacute pulmonary toxicity of low dose of ultrafine colloidal silica particles in mice after intratracheal instillation. Toxicol. Pathol. 2006, 34:958-965.
21. Kermanizadeh A., Gaiser B.K., Hutchison G.R., Stone V. An in vitro liver model - assessing oxidative stress and genotoxicity following exposure of hepatocytes to a panel of engineered nanoparticles. Part. Fibre Toxicol. 2012, 9:28.
22. Kipnis E., Hansen K., Sawa T., Moriyama K., Zurawei A., Ishizaka A., Wiener-Kronish J. Proteomic analysis of undiluted lung epithelial lining fluid. Chest 2008, 134(2):338-345.
23. Ku T., Gill S., Lobenberg R., Azarmi S., Roa W., Prenner E.J. Size dependent interactions of nanoparticles with lung surfactant model systems and the significant impact on surface potential. J. Nanosci. Nanotechnol. 2008, 8:2971-2978.
24. Lipka J., Semmler-Behnke M., Sperling R.A., Wenk A., Takenaka S., Schleh C., et al. Biodistribution of PEG-modified gold nanoparticles following intratracheal instillation and intravenous injection. Biomaterials 2010, 31:6574.
25. Lundqvist M., Stigler J., Elia G., Lynch I., Cedervall T., Dawson K.A. Nanoparticle size and surface properties determine the protein corona with possible implications for biological impacts. Proc. Natl. Acad. Sci. U. S. A. 2008, 105:14265-14270.
26. Monopoli M.P., Walczyk D., Campbell A., Elia G., Lynch I., Badelli Bombelli F., et al. Physical-chemical aspects of protein corona: relevance to in vitro and in vivo biological impacts of nanoparticles. J. Am. Chem. Soc. 2011, 133(8):2525-2534.
27. Nel A.E., Madler L., Velegol D., Xia T., Hoek E.M., Somasundaran P., et al. Understanding biophysicochemical interactions at the nano-bio interface. Nat. Mater. 2009, 8:543-557.
28. Oberdorster G., Ferin J., Lehnert B.E. Correlation between particle size, in vivo particle persistence, and lung injury. Environ. Health Perspect. 1994, 102(Suppl 5):173-179.
29. Oberdorster G., Sharp Z., Atudorei V., Elder A., Gelein R., Lunts A., et al. Extrapulmonary translocation of ultrafine carbon particles following whole-body inhalation exposure of rats. J. Toxicol. Environ. Health 2002, 65:1531-1543.
30. Sadauskas E., Jacobsen N.R., Danscher G., Stoltenberg M., Vogel U., Larsen A., Kreyling W., Wallin H. Biodistribution of gold nanoparticles in mouse lung following intratracheal instillation. Chem. Cent. J. 2009, 3:16.
31. Schleh C., Semmler-Behnke M., Lipka J., Wenk A., Hirn S., Schäffler M., et al. Size and surface charge of gold nanoparticles determine absorption across intestinal barriers and accumulation in secondary target organs after oral administration. Nanotoxicology 2012, 6:36-46.
32. Schleh C., Kreyling W.G., Lehr C.M. Pulmonary surfactant is indispensable in order to simulate the in vivo situation. Part. Fibre Toxicol. 2013, 10:6.
33. Stayton I., Winiarz J., Shannon K. Study of uptake and loss of silica nanoparticles in living human lung epithelial cells at single cell level. Anal. Bioanal. Chem. 2009, 394:1595-1608.
34. Wang W., Li Y., Liu X., Jin M., Du H., Liu Y., Huang P., Zhou X., Yuan L., Sun Z. Multinucleation and cell dysfunction induced by amorphous silica nanoparticles in an L-02 human hepatic cell line. Int. J. Nanomed. 2013, 8(1):3533-3541.
35. 2 particle formulations: impact of surface treatments on particle toxicity. Toxicol. Sci. 2005, 88:514-524.