In vivo nanoneurotoxicity screening using oxidative stress and neuroinflammation paradigms

Nanomedicine: Nanotechnology, Biology, and Medicine

Volumn 9, Issue 7, 2013, Pages 1057-1066

  Kim, Youngsoon ^a   Kong, Seong Deok ^b   Chen, Li Han ^b   Pisanic, Thomas R ^c   Jin, Sungho ^b   Shubayev, Veronica I ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c Johns Hopkins University   (United States)

Author keywords

Blood brain barrier; Iron oxide; Magnetic nanoparticles; Nanotoxicity; Theranostic

Indexed keywords

APOPTOTIC SIGNALING; BLOOD-BRAIN BARRIER; IRON OXIDE NANOPARTICLE; IRON OXIDE NANOPARTICLES (IONPS); MAGNETIC NANO-PARTICLES; NANOTOXICITY; PERIPHERAL NERVOUS SYSTEM; THERANOSTIC;

ENDOTHELIAL CELLS; IRON OXIDES; NEUROIMAGING;

METAL NANOPARTICLES;

IRON OXIDE NANOPARTICLE; METAL OXIDE; NANOPARTICLE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CIRCULATION; CONTROLLED STUDY; ENDOTHELIUM CELL; FEMALE; GLIA; IMMUNOCOMPETENT CELL; IN VIVO STUDY; INFLAMMATION; LYMPHOCYTE; MACROPHAGE; MAGNETOMETRY; NANONEUROTOXICITY; NERVOUS SYSTEM INFLAMMATION; NEUROTOXICITY; NONHUMAN; OXIDATIVE STRESS; PERIPHERAL NERVOUS SYSTEM; RAT; SCIATIC NERVE; SCREENING;

RATTUS;

BLOOD-BRAIN BARRIER; IRON OXIDE; MAGNETIC NANOPARTICLES; NANOTOXICITY; THERANOSTIC;

ANIMALS; ANTIOXIDANTS; APOPTOSIS; FEMALE; INFLAMMATION; MAGNETITE NANOPARTICLES; NEUROTOXINS; OXIDATIVE STRESS; PHENOTYPE; PHYSICOCHEMICAL PHENOMENA; POLYETHYLENE GLYCOLS; RATS; RATS, SPRAGUE-DAWLEY; SCIATIC NERVE; SIGNAL TRANSDUCTION; SUCCIMER; SURFACE PROPERTIES;

EID: 84884283916     PISSN: 15499634     EISSN: 15499642     Source Type: Journal    
DOI: 10.1016/j.nano.2013.05.002     Document Type: Article

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