-
1
-
-
77956639427
-
KuM, Coffman EJ, Truong TT, Vargas SO, Lander ES, Haber DA, Bernstein BE
-
Aiden AP, Rivera MN, Rheinbay E, KuM, Coffman EJ, Truong TT, Vargas SO, Lander ES, Haber DA, Bernstein BE. 2010. Wilms tumor chromatin profiles highlight stem cell properties and a renal developmental network. Cell Stem Cell 6: 591–602.
-
(2010)
Wilms Tumor Chromatin Profiles Highlight Stem Cell Properties and a Renal Developmental Network. Cell Stem Cell
, vol.6
, pp. 591-602
-
-
Aiden, A.P.1
Rivera, M.N.2
Rheinbay, E.3
-
2
-
-
5744245556
-
Differential expression of a novel ankyrin containing E3 ubiquitin-protein ligase, Hace1, in sporadic Wilms’ tumor versus normal kidney
-
Anglesio MS, Evdokimova V, Melnyk N, Zhang L, Fernandez CV, Grundy PE, Leach S, Marra MA, Brooks-Wilson AR, Penninger J, et al. 2004. Differential expression of a novel ankyrin containing E3 ubiquitin-protein ligase, Hace1, in sporadic Wilms’ tumor versus normal kidney. Hum Mol Genet 13: 2061–2074.
-
(2004)
Hum Mol Genet
, vol.13
, pp. 2061-2074
-
-
Anglesio, M.S.1
Evdokimova, V.2
Melnyk, N.3
Zhang, L.4
Fernandez, C.V.5
Grundy, P.E.6
Leach, S.7
Marra, M.A.8
Brooks-Wilson, A.R.9
Penninger, J.10
-
3
-
-
84857644144
-
Germline mutations in DIS3L2 cause the Perlman syndrome of overgrowth and Wilms tumor susceptibility
-
Astuti D, Morris MR, Cooper WN, Staals RH, Wake NC, Fews GA, Gill H, Gentle D, Shuib S, Ricketts CJ, et al. 2012. Germline mutations in DIS3L2 cause the Perlman syndrome of overgrowth and Wilms tumor susceptibility. Nat Genet 44: 277–284.
-
(2012)
Nat Genet
, vol.44
, pp. 277-284
-
-
Astuti, D.1
Morris, M.R.2
Cooper, W.N.3
Staals, R.H.4
Wake, N.C.5
Fews, G.A.6
Gill, H.7
Gentle, D.8
Shuib, S.9
Ricketts, C.J.10
-
4
-
-
78649634206
-
Germline DICER1 mutations and familial cystic nephroma
-
Bahubeshi A, Bal N, Rio Frio T, Hamel N, Pouchet C, Yilmaz A, Bouron-Dal Soglio D, Williams GM, Tischkowitz M, Priest JR, et al. 2010. Germline DICER1 mutations and familial cystic nephroma. J Med Genet 47: 863–866.
-
(2010)
J Med Genet
, vol.47
, pp. 863-866
-
-
Bahubeshi, A.1
Bal, N.2
Rio Frio, T.3
Hamel, N.4
Pouchet, C.5
Yilmaz, A.6
Bouron-Dal Soglio, D.7
Williams, G.M.8
Tischkowitz, M.9
Priest, J.R.10
-
5
-
-
0028168146
-
Anaplastic Wilms’ tumour, a subtype displaying poor prognosis, harbours p53 gene mutations
-
Bardeesy N, Falkoff D, Petruzzi M-J, Nowak N, Zabel B, Adam M, Aguiar MC, Grundy P, Shows T, Pelletier J. 1994. Anaplastic Wilms’ tumour, a subtype displaying poor prognosis, harbours p53 gene mutations. Nat Genet 7: 91–97.
-
(1994)
Nat Genet
, vol.7
, pp. 91-97
-
-
Bardeesy, N.1
Falkoff, D.2
Petruzzi, M.-J.3
Nowak, N.4
Zabel, B.5
Adam, M.6
Aguiar, M.C.7
Grundy, P.8
Shows, T.9
Pelletier, J.10
-
6
-
-
0034660561
-
Role of N-myc in the developing mouse kidney
-
Bates CM, Kharzai S, Erwin T, Rossant J, Parada LF. 2000. Role of N-myc in the developing mouse kidney. Dev Biol 222: 317–325.
-
(2000)
Dev Biol
, vol.222
, pp. 317-325
-
-
Bates, C.M.1
Kharzai, S.2
Erwin, T.3
Rossant, J.4
Parada, L.F.5
-
7
-
-
0025271523
-
Nephrogenic rests, nephroblastomatosis, and the pathogenesis of Wilms’ tumor
-
Beckwith JB, Kiviat NB, Bonadio JF. 1990. Nephrogenic rests, nephroblastomatosis, and the pathogenesis of Wilms’ tumor. Pediatr Pathol 10: 1–36.
-
(1990)
Pediatr Pathol
, vol.10
, pp. 1-36
-
-
Beckwith, J.B.1
Kiviat, N.B.2
Bonadio, J.F.3
-
8
-
-
80051680291
-
A continuum model for tumour suppression
-
Berger AH, Knudson AG, Pandolfi PP. 2011. A continuum model for tumour suppression. Nature 476: 163–169.
-
(2011)
Nature
, vol.476
, pp. 163-169
-
-
Berger, A.H.1
Knudson, A.G.2
Pandolfi, P.P.3
-
9
-
-
0025099787
-
Isolation and characterization of a zinc finger polypeptide gene at the human chromosome 11 Wilms’ tumor locus
-
Call KM, Glaser T, Ito CY, Buckler AJ, Pelletier J, Haber DA, Rose EA, Kral A, Yeger H, Lewis WH, et al. 1990. Isolation and characterization of a zinc finger polypeptide gene at the human chromosome 11 Wilms’ tumor locus. Cell 60: 509–520.
-
(1990)
Cell
, vol.60
, pp. 509-520
-
-
Call, K.M.1
Glaser, T.2
Ito, C.Y.3
Buckler, A.J.4
Pelletier, J.5
Haber, D.A.6
Rose, E.A.7
Kral, A.8
Yeger, H.9
Lewis, W.H.10
-
10
-
-
84877757514
-
A role for the Perlman syndrome exonuclease Dis3l2 in the Lin28– let-7 pathway
-
Chang HM, Triboulet R, Thornton JE, Gregory RI. 2013. A role for the Perlman syndrome exonuclease Dis3l2 in the Lin28– let-7 pathway. Nature 497: 244–248.
-
(2013)
Nature
, vol.497
, pp. 244-248
-
-
Chang, H.M.1
Triboulet, R.2
Thornton, J.E.3
Gregory, R.I.4
-
11
-
-
84924682511
-
Comparative methylome analysis identifies new tumour subtypes and biomarkers for transformation of nephrogenic rests into Wilms tumour
-
Charlton J, Williams RD, Sebire NJ, Popov S, Vujanic G, Chagtai T, Alcaide-German M, Morris T, Butcher LM, Guilhamon P, et al. 2015. Comparative methylome analysis identifies new tumour subtypes and biomarkers for transformation of nephrogenic rests into Wilms tumour. Genome Medicine 7: 11.
-
(2015)
Genome Medicine
, vol.7
-
-
Charlton, J.1
Williams, R.D.2
Sebire, N.J.3
Popov, S.4
Vujanic, G.5
Chagtai, T.6
Alcaide-German, M.7
Morris, T.8
Butcher, L.M.9
Guilhamon, P.10
-
12
-
-
0027080193
-
Embryonic lethality in mice homozygous for a targeted disruption of the N-myc gene
-
Charron J, Malynn BA, Fisher P, Stewart V, Jeannotte L, Goff SP, Robertson EJ, Alt FW. 1992. Embryonic lethality in mice homozygous for a targeted disruption of the N-myc gene. Genes Dev 6: 2248–2257.
-
(1992)
Genes Dev
, vol.6
, pp. 2248-2257
-
-
Charron, J.1
Malynn, B.A.2
Fisher, P.3
Stewart, V.4
Jeannotte, L.5
Goff, S.P.6
Robertson, E.J.7
Alt, F.W.8
-
13
-
-
84855264059
-
Acute multiple organ failure in adult mice deleted for the developmental regulator Wt1
-
e1002404
-
Chau YY, Brownstein D, Mjoseng H, Lee WC, Buza-Vidas N, Nerlov C, Jacobsen SE, Perry P, Berry R, Thornburn A, et al. 2011. Acute multiple organ failure in adult mice deleted for the developmental regulator Wt1. PLoS Genet 7: e1002404.
-
(2011)
Plos Genet
, vol.7
-
-
Chau, Y.Y.1
Brownstein, D.2
Mjoseng, H.3
Lee, W.C.4
Buza-Vidas, N.5
Nerlov, C.6
Jacobsen, S.E.7
Perry, P.8
Berry, R.9
Thornburn, A.10
-
14
-
-
36049007134
-
Hypomethylation and aberrant expression of the glioma pathogenesis-related 1 gene in Wilms tumors
-
Chilukamarri L, Hancock AL, Malik S, Zabkiewicz J, Baker JA, Greenhough A, Dallosso AR, Huang TH, Royer-Pokora B, Brown KW, et al. 2007. Hypomethylation and aberrant expression of the glioma pathogenesis-related 1 gene in Wilms tumors. Neoplasia 9: 970–978.
-
(2007)
Neoplasia
, vol.9
, pp. 970-978
-
-
Chilukamarri, L.1
Hancock, A.L.2
Malik, S.3
Zabkiewicz, J.4
Baker, J.A.5
Greenhough, A.6
Dallosso, A.R.7
Huang, T.H.8
Royer-Pokora, B.9
Brown, K.W.10
-
15
-
-
81255201334
-
B-Catenin and K-RAS synergize to form primitive renal epithelial tumors with features of epithelial Wilms’ tumors
-
Clark PE, Polosukhina D, Love H, Correa H, Coffin C, Perlman EJ, de Caestecker M, Moses HL, Zent R. 2011. b-Catenin and K-RAS synergize to form primitive renal epithelial tumors with features of epithelial Wilms’ tumors. Am J Pathol 179: 3045–3055.
-
(2011)
Am J Pathol
, vol.179
, pp. 3045-3055
-
-
Clark, P.E.1
Polosukhina, D.2
Love, H.3
Correa, H.4
Coffin, C.5
Perlman, E.J.6
De Caestecker, M.7
Moses, H.L.8
Zent, R.9
-
16
-
-
77952946956
-
Patterning a complex organ: Branching morphogenesis and nephron segmentation in kidney development
-
Costantini F, Kopan R. 2010. Patterning a complex organ: branching morphogenesis and nephron segmentation in kidney development. Dev Cell 18: 698–712.
-
(2010)
Dev Cell
, vol.18
, pp. 698-712
-
-
Costantini, F.1
Kopan, R.2
-
17
-
-
84970405887
-
Spontaneous tumours in young animals
-
Cotchin E. 1975. Spontaneous tumours in young animals. Proc R Soc Med 68: 653–655.
-
(1975)
Proc R Soc Med
, vol.68
, pp. 653-655
-
-
Cotchin, E.1
-
18
-
-
0013953358
-
Chromosome constitution of nephroblastomas
-
Cox D. 1966. Chromosome constitution of nephroblastomas. Cancer 19: 1217–1224.
-
(1966)
Cancer
, vol.19
, pp. 1217-1224
-
-
Cox, D.1
-
19
-
-
73649141296
-
Frequent long-range epigenetic silencing of protocadherin gene clusters on chromosome 5q31 in Wilms’ tumor
-
e1000745
-
Dallosso AR, Hancock AL, Szemes M, Moorwood K, Chilukamarri L, Tsai HH, Sarkar A, Barasch J, Vuononvirta R, Jones C, et al. 2009. Frequent long-range epigenetic silencing of protocadherin gene clusters on chromosome 5q31 in Wilms’ tumor. PLoS Genet 5: e1000745.
-
(2009)
Plos Genet
, vol.5
-
-
Dallosso, A.R.1
Hancock, A.L.2
Szemes, M.3
Moorwood, K.4
Chilukamarri, L.5
Tsai, H.H.6
Sarkar, A.7
Barasch, J.8
Vuononvirta, R.9
Jones, C.10
-
20
-
-
84883741356
-
Stromal–epithelial crosstalk regulates kidney progenitor cell differentiation
-
Das A, Tanigawa S, Karner CM, Xin M, Lum L, Chen C, Olson EN, Perantoni AO, Carroll TJ. 2013. Stromal–epithelial crosstalk regulates kidney progenitor cell differentiation. Nat Cell Biol 15: 1035–1044.
-
(2013)
Nat Cell Biol
, vol.15
, pp. 1035-1044
-
-
Das, A.1
Tanigawa, S.2
Karner, C.M.3
Xin, M.4
Lum, L.5
Chen, C.6
Olson, E.N.7
Perantoni, A.O.8
Carroll, T.J.9
-
21
-
-
1642514813
-
Development of an siRNA-based method for repressing specific genes in renal organ culture and its use to show that the Wt1 tumour suppressor is required for nephron differentiation
-
Davies JA, Ladomery M, Hohenstein P, Michael L, Shafe A, Spraggon L, Hastie N. 2004. Development of an siRNA-based method for repressing specific genes in renal organ culture and its use to show that the Wt1 tumour suppressor is required for nephron differentiation. Hum Mol Genet 13: 235–246.
-
(2004)
Hum Mol Genet
, vol.13
, pp. 235-246
-
-
Davies, J.A.1
Ladomery, M.2
Hohenstein, P.3
Michael, L.4
Shafe, A.5
Spraggon, L.6
Hastie, N.7
-
22
-
-
33745728174
-
Multiple imprinted and stemness genes provide a link between normal and tumor progenitor cells of the developing human kidney
-
Dekel B, Metsuyanim S, Schmidt-Ott KM, Fridman E, Jacob- Hirsch J, Simon A, Pinthus J, Mor Y, Barasch J, Amariglio N, et al. 2006. Multiple imprinted and stemness genes provide a link between normal and tumor progenitor cells of the developing human kidney. Cancer Res 66: 6040–6049.
-
(2006)
Cancer Res
, vol.66
, pp. 6040-6049
-
-
Dekel, B.1
Metsuyanim, S.2
Schmidt-Ott, K.M.3
Fridman, E.4
Jacob-Hirsch, J.5
Simon, A.6
Pinthus, J.7
Mor, Y.8
Barasch, J.9
Amariglio, N.10
-
23
-
-
65349123354
-
A genome-scale RNAi screen for Oct4 modulators defines a role of the Paf1 complex for embryonic stem cell identity
-
Ding L, Paszkowski-Rogacz M, Nitzsche A, Slabicki MM, Heninger AK, de Vries I, Kittler R, Junqueira M, Shevchenko A, Schulz H, et al. 2009. A genome-scale RNAi screen for Oct4 modulators defines a role of the Paf1 complex for embryonic stem cell identity. Cell Stem Cell 4: 403–415.
-
(2009)
Cell Stem Cell
, vol.4
, pp. 403-415
-
-
Ding, L.1
Paszkowski-Rogacz, M.2
Nitzsche, A.3
Slabicki, M.M.4
Heninger, A.K.5
De Vries, I.6
Kittler, R.7
Junqueira, M.8
Shevchenko, A.9
Schulz, H.10
-
24
-
-
70349673602
-
Loss of heterozygosity at 2q37 in sporadic Wilms’ tumor: Putative role for miR-562
-
Drake KM, Ruteshouser EC, Natrajan R, Harbor P, Wegert J, Gessler M, Pritchard-Jones K, Grundy P, Dome J, Huff V, et al. 2009. Loss of heterozygosity at 2q37 in sporadic Wilms’ tumor: putative role for miR-562. Clin Cancer Res 15: 5985–5992.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 5985-5992
-
-
Drake, K.M.1
Ruteshouser, E.C.2
Natrajan, R.3
Harbor, P.4
Wegert, J.5
Gessler, M.6
Pritchard-Jones, K.7
Grundy, P.8
Dome, J.9
Huff, V.10
-
25
-
-
0037371987
-
Satellite DNA hypomethylation in karyotyped Wilms tumors
-
Ehrlich M, Hopkins NE, Jiang G, Dome JS, Yu MC, Woods CB, Tomlinson GE, Chintagumpala M, Champagne M, Dillerg L, et al. 2003. Satellite DNA hypomethylation in karyotyped Wilms tumors. Cancer Genet Cytogenet 141: 97–105.
-
(2003)
Cancer Genet Cytogenet
, vol.141
, pp. 97-105
-
-
Ehrlich, M.1
Hopkins, N.E.2
Jiang, G.3
Dome, J.S.4
Yu, M.C.5
Woods, C.B.6
Tomlinson, G.E.7
Chintagumpala, M.8
Champagne, M.9
Dillerg, L.10
-
26
-
-
77949771437
-
Nuclear accumulation of b-catenin protein indicates activation of wnt signaling in chemically induced rat nephroblastomas
-
Ehrlich D, Bruder E, Thome MA, Gutt CN, von Knebel Doeberitz M, Niggli F, Perantoni AO, Koesters R. 2010. Nuclear accumulation of b-catenin protein indicates activation of wnt signaling in chemically induced rat nephroblastomas. Pediatr Dev Pathol 13: 1–8.
-
(2010)
Pediatr Dev Pathol
, vol.13
, pp. 1-8
-
-
Ehrlich, D.1
Bruder, E.2
Thome, M.A.3
Gutt, C.N.4
Von Knebel Doeberitz, M.5
Niggli, F.6
Perantoni, A.O.7
Koesters, R.8
-
28
-
-
80052720433
-
A Wt1-controlled chromatin switching mechanism underpins tissue-specific Wnt4 activation and repression
-
Essafi A, Webb A, Berry RL, Slight J, Burn SF, Spraggon L, Velecela V, Martinez-Estrada OM, Wiltshire JH, Roberts SG, et al. 2011. A Wt1-controlled chromatin switching mechanism underpins tissue-specific Wnt4 activation and repression. Dev Cell 21: 559–574.
-
(2011)
Dev Cell
, vol.21
, pp. 559-574
-
-
Essafi, A.1
Webb, A.2
Berry, R.L.3
Slight, J.4
Burn, S.F.5
Spraggon, L.6
Velecela, V.7
Martinez-Estrada, O.M.8
Wiltshire, J.H.9
Roberts, S.G.10
-
29
-
-
84880426860
-
The new pig on the block: Modelling cancer in pigs
-
Flisikowska T, Kind A, Schnieke A. 2013. The new pig on the block: modelling cancer in pigs. Transgenic Res 22: 673–680.
-
(2013)
Transgenic Res
, vol.22
, pp. 673-680
-
-
Flisikowska, T.1
Kind, A.2
Schnieke, A.3
-
30
-
-
81255136937
-
Extending the phenotypes associated with DICER1 mutations
-
Foulkes WD, Bahubeshi A, Hamel N, Pasini B, Asioli S, Baynam G, Choong CS, Charles A, Frieder RP, Dishop MK, et al. 2011. Extending the phenotypes associated with DICER1 mutations. Hum Mutat 32: 1381–1384.
-
(2011)
Hum Mutat
, vol.32
, pp. 1381-1384
-
-
Foulkes, W.D.1
Bahubeshi, A.2
Hamel, N.3
Pasini, B.4
Asioli, S.5
Baynam, G.6
Choong, C.S.7
Charles, A.8
Frieder, R.P.9
Dishop, M.K.10
-
32
-
-
34548217651
-
Maximizing mouse cancer models
-
Frese KK, Tuveson DA. 2007. Maximizing mouse cancer models. Nat Rev Cancer 7: 645–658.
-
(2007)
Nat Rev Cancer
, vol.7
, pp. 645-658
-
-
Frese, K.K.1
Tuveson, D.A.2
-
33
-
-
34548831074
-
Sequential WT1 and CTNNB1 mutations and alterations of b-catenin localisation in intralobar nephrogenic rests and associated Wilms tumours: Two case studies
-
Fukuzawa R, Heathcott RW, More HE, Reeve AE. 2007. Sequential WT1 and CTNNB1 mutations and alterations of b-catenin localisation in intralobar nephrogenic rests and associated Wilms tumours: two case studies. J Clin Pathol 60: 1013–1016.
-
(2007)
J Clin Pathol
, vol.60
, pp. 1013-1016
-
-
Fukuzawa, R.1
Heathcott, R.W.2
More, H.E.3
Reeve, A.E.4
-
34
-
-
78149340959
-
WTX mutations can occur both early and late in the pathogenesis of Wilms tumour
-
Fukuzawa R, Holman SK, Chow CW, Savarirayan R, Reeve AE, Robertson SP. 2010. WTX mutations can occur both early and late in the pathogenesis of Wilms tumour. J Med Genet 47: 791–794.
-
(2010)
J Med Genet
, vol.47
, pp. 791-794
-
-
Fukuzawa, R.1
Holman, S.K.2
Chow, C.W.3
Savarirayan, R.4
Reeve, A.E.5
Robertson, S.P.6
-
35
-
-
84865245097
-
Clinically relevant subsets identified by gene expression patterns support a revised ontogenic model of Wilms tumor: A children’s oncology group study
-
Gadd S, Huff V, Huang CC, Ruteshouser EC, Dome JS, Grundy PE, Breslow N, Jennings L, Green DM, Beckwith JB, et al. 2012. Clinically relevant subsets identified by gene expression patterns support a revised ontogenic model of Wilms tumor: a children’s oncology group study. Neoplasia 14: 742–756.
-
(2012)
Neoplasia
, vol.14
, pp. 742-756
-
-
Gadd, S.1
Huff, V.2
Huang, C.C.3
Ruteshouser, E.C.4
Dome, J.S.5
Grundy, P.E.6
Breslow, N.7
Jennings, L.8
Green, D.M.9
Beckwith, J.B.10
-
36
-
-
7644239147
-
The Wt1+/R394W mouse displays glomerulosclerosis and early-onset renal failure characteristic of human Denys-Drash syndrome
-
Gao F, Maiti S, Sun G, Ordonez NG, Udtha M, Deng JM, Behringer RR, Huff V. 2004. The Wt1+/R394W mouse displays glomerulosclerosis and early-onset renal failure characteristic of human Denys-Drash syndrome. Mol Cell Biol 24: 9899–9910.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 9899-9910
-
-
Gao, F.1
Maiti, S.2
Sun, G.3
Ordonez, N.G.4
Udtha, M.5
Deng, J.M.6
Behringer, R.R.7
Huff, V.8
-
37
-
-
84878425125
-
Focal segmental glomerulosclerosis is induced by microRNA-193a and its downregulation of WT1
-
Gebeshuber CA, Kornauth C, Dong L, Sierig R, Seibler J, Reiss M, Tauber S, Bilban M, Wang S, Kain R, et al. 2013. Focal segmental glomerulosclerosis is induced by microRNA-193a and its downregulation of WT1. Nat Med 19: 481–487.
-
(2013)
Nat Med
, vol.19
, pp. 481-487
-
-
Gebeshuber, C.A.1
Kornauth, C.2
Dong, L.3
Sierig, R.4
Seibler, J.5
Reiss, M.6
Tauber, S.7
Bilban, M.8
Wang, S.9
Kain, R.10
-
38
-
-
0025098654
-
Homozygous deletion in Wilms tumours of a zinc-finger gene identified by chromosome jumping
-
Gessler M, Poustka A, Cavenee W, Neve RL, Orkin SH, Bruns GA. 1990. Homozygous deletion in Wilms tumours of a zinc-finger gene identified by chromosome jumping. Nature 343: 774–778.
-
(1990)
Nature
, vol.343
, pp. 774-778
-
-
Gessler, M.1
Poustka, A.2
Cavenee, W.3
Neve, R.L.4
Orkin, S.H.5
Bruns, G.A.6
-
39
-
-
84858219643
-
Activation of b-catenin is a late event in the pathogenesis of nephroblastomas and rarely correlated with genetic changes of the APC gene
-
Grill C, Sunitsch S, Hatz M, Hauser-Kronberger C, Leuschner I, Hoefler G, Guertl B. 2011. Activation of b-catenin is a late event in the pathogenesis of nephroblastomas and rarely correlated with genetic changes of the APC gene. Pathology 43: 702–706.
-
(2011)
Pathology
, vol.43
, pp. 702-706
-
-
Grill, C.1
Sunitsch, S.2
Hatz, M.3
Hauser-Kronberger, C.4
Leuschner, I.5
Hoefler, G.6
Guertl, B.7
-
41
-
-
77955686669
-
Is predisposition for nephroblastoma linked to polymorphisms of the WTX gene?
-
Guertl B, Leuschner I, Guelly C, Ebner B, Kronberger C, Hoefler G. 2010. Is predisposition for nephroblastoma linked to polymorphisms of the WTX gene?. Pathol Oncol Res 16: 189–191.
-
(2010)
Pathol Oncol Res
, vol.16
, pp. 189-191
-
-
Guertl, B.1
Leuschner, I.2
Guelly, C.3
Ebner, B.4
Kronberger, C.5
Hoefler, G.6
-
42
-
-
0037087593
-
WT1 is a key regulator of podocyte function: Reduced expression levels cause crescentic glomerulonephritis and mesangial sclerosis
-
Guo JK, Menke AL, Gubler MC, Clarke AR, Harrison D, Hammes A, Hastie ND, Schedl A. 2002. WT1 is a key regulator of podocyte function: reduced expression levels cause crescentic glomerulonephritis and mesangial sclerosis. Hum Mol Genet 11: 651–659.
-
(2002)
Hum Mol Genet
, vol.11
, pp. 651-659
-
-
Guo, J.K.1
Menke, A.L.2
Gubler, M.C.3
Clarke, A.R.4
Harrison, D.5
Hammes, A.6
Hastie, N.D.7
Schedl, A.8
-
43
-
-
0035839099
-
Two splice variants of the Wilms’ tumor 1 gene have distinct functions during sex determination and nephron formation
-
Hammes A, Guo JK, Lutsch G, Leheste JR, Landrock D, Ziegler U, Gubler MC, Schedl A. 2001. Two splice variants of the Wilms’ tumor 1 gene have distinct functions during sex determination and nephron formation. Cell 106: 319–329.
-
(2001)
Cell
, vol.106
, pp. 319-329
-
-
Hammes, A.1
Guo, J.K.2
Lutsch, G.3
Leheste, J.R.4
Landrock, D.5
Ziegler, U.6
Gubler, M.C.7
Schedl, A.8
-
44
-
-
84907342992
-
Germline mutations in the PAF1 complex gene CTR9 predispose to Wilms tumour
-
Hanks S, Perdeaux ER, Seal S, Ruark E, Mahamdallie SS, Murray A, Ramsay E, Del Vecchio Duarte S, Zachariou A, de Souza B, et al. 2014. Germline mutations in the PAF1 complex gene CTR9 predispose to Wilms tumour. Nat Commun 5: 4398.
-
(2014)
Nat Commun
, vol.5
-
-
Hanks, S.1
Perdeaux, E.R.2
Seal, S.3
Ruark, E.4
Mahamdallie, S.S.5
Murray, A.6
Ramsay, E.7
Del Vecchio Duarte, S.8
Zachariou, A.9
De Souza, B.10
-
45
-
-
0037108859
-
Deregulation of Caspase 8 and 10 expression in pediatric tumors and cell lines
-
Harada K, Toyooka S, Shivapurkar N, Maitra A, Reddy JL, Matta H, Miyajima K, Timmons CF, Tomlinson GE, Mastrangelo D, et al. 2002. Deregulation of Caspase 8 and 10 expression in pediatric tumors and cell lines. Cancer Res 62: 5897–5901.
-
(2002)
Cancer Res
, vol.62
, pp. 5897-5901
-
-
Harada, K.1
Toyooka, S.2
Shivapurkar, N.3
Maitra, A.4
Reddy, J.L.5
Matta, H.6
Miyajima, K.7
Timmons, C.F.8
Tomlinson, G.E.9
Mastrangelo, D.10
-
46
-
-
84884938538
-
Identification of human nephron progenitors capable of generation of kidney structures and functional repair of chronic renal disease
-
Harari-Steinberg O, Metsuyanim S, Omer D, Gnatek Y, Gershon R, Pri-Chen S, Ozdemir DD, Lerenthal Y, Noiman T, Ben-Hur H, et al. 2013. Identification of human nephron progenitors capable of generation of kidney structures and functional repair of chronic renal disease. EMBO Mol Med 5: 1556–1568.
-
(2013)
EMBO Mol Med
, vol.5
, pp. 1556-1568
-
-
Harari-Steinberg, O.1
Metsuyanim, S.2
Omer, D.3
Gnatek, Y.4
Gershon, R.5
Pri-Chen, S.6
Ozdemir, D.D.7
Lerenthal, Y.8
Noiman, T.9
Ben-Hur, H.10
-
47
-
-
0022218968
-
Differential renal tumor response to N-ethylnitrosourea and dimethylnitrosamine in the Nb rat: Basis for a new rodent model of nephroblastoma
-
Hard GC. 1985. Differential renal tumor response to N-ethylnitrosourea and dimethylnitrosamine in the Nb rat: basis for a new rodent model of nephroblastoma. Carcinogenesis 6: 1551–1558.
-
(1985)
Carcinogenesis
, vol.6
, pp. 1551-1558
-
-
Hard, G.C.1
-
48
-
-
50249095737
-
Combined BubR1 protein down-regulation and RASSF1A hypermethylation in Wilms tumors with diverse cytogenetic changes
-
Haruta M, Matsumoto Y, Izumi H, Watanabe N, Fukuzawa M, Matsuura S, Kaneko Y. 2008. Combined BubR1 protein down-regulation and RASSF1A hypermethylation in Wilms tumors with diverse cytogenetic changes. Mol Carcinog 47: 660–666.
-
(2008)
Mol Carcinog
, vol.47
, pp. 660-666
-
-
Haruta, M.1
Matsumoto, Y.2
Izumi, H.3
Watanabe, N.4
Fukuzawa, M.5
Matsuura, S.6
Kaneko, Y.7
-
49
-
-
68749102148
-
TUT4 in concert with Lin28 suppresses microRNA biogenesis through pre-microRNA uridylation
-
Heo I, Joo C, Kim YK, Ha M, Yoon MJ, Cho J, Yeom KH, Han J, Kim VN. 2009. TUT4 in concert with Lin28 suppresses microRNA biogenesis through pre-microRNA uridylation. Cell 138: 696–708.
-
(2009)
Cell
, vol.138
, pp. 696-708
-
-
Heo, I.1
Joo, C.2
Kim, Y.K.3
Ha, M.4
Yoon, M.J.5
Cho, J.6
Yeom, K.H.7
Han, J.8
Kim, V.N.9
-
50
-
-
26644444345
-
Global loss of imprinting leads to widespread tumorigenesis in adult mice
-
Holm TM, Jackson-Grusby L, Brambrink T, Yamada Y, Rideout WM 3rd, Jaenisch R. 2005. Global loss of imprinting leads to widespread tumorigenesis in adult mice. Cancer Cell 8: 275–285.
-
(2005)
Cancer Cell
, vol.8
, pp. 275-285
-
-
Holm, T.M.1
Jackson-Grusby, L.2
Brambrink, T.3
Yamada, Y.4
Rideout, W.M.5
Jaenisch, R.6
-
51
-
-
84922225818
-
Single-step generation of rabbits carrying a targeted allele of the tyrosinase gene using CRISPR/Cas9
-
Honda A, Hirose M, Sankai T, Yasmin L, Yuzawa K, Honsho K, Izu H, Iguchi A, Ikawa M, Ogura A 2014. Single-step generation of rabbits carrying a targeted allele of the tyrosinase gene using CRISPR/Cas9. Exp Anim doi: 1538/expanim.14-0034.
-
(2014)
Exp Anim
-
-
Honda, A.1
Hirose, M.2
Sankai, T.3
Yasmin, L.4
Yuzawa, K.5
Honsho, K.6
Izu, H.7
Iguchi, A.8
Ikawa, M.9
Ogura, A.10
-
52
-
-
78650943634
-
Wt1 ablation and Igf2 upregulation in mice result in Wilms tumors with elevated ERK1/2 phosphorylation
-
Hu Q, Gao F, Tian W, Ruteshouser EC, Wang Y, Lazar A, Stewart J, Strong LC, Behringer RR, Huff V. 2011. Wt1 ablation and Igf2 upregulation in mice result in Wilms tumors with elevated ERK1/2 phosphorylation. J Clin Invest 121: 174–183.
-
(2011)
J Clin Invest
, vol.121
, pp. 174-183
-
-
Hu, Q.1
Gao, F.2
Tian, W.3
Ruteshouser, E.C.4
Wang, Y.5
Lazar, A.6
Stewart, J.7
Strong, L.C.8
Behringer, R.R.9
Huff, V.10
-
53
-
-
79551575384
-
Altered expression of imprinted genes in Wilms tumors
-
Hubertus J, Lacher M, Rottenkolber M, Muller-Hocker J, Berger M, Stehr M, von Schweinitz D, Kappler R. 2011. Altered expression of imprinted genes in Wilms tumors. Oncol Rep 25: 817–823.
-
(2011)
Oncol Rep
, vol.25
, pp. 817-823
-
-
Hubertus, J.1
Lacher, M.2
Rottenkolber, M.3
Muller-Hocker, J.4
Berger, M.5
Stehr, M.6
Von Schweinitz, D.7
Kappler, R.8
-
54
-
-
84879354172
-
Selective methylation of CpGs at regulatory binding sites controls NNAT expression in Wilms tumors
-
Hubertus J, Zitzmann F, Trippel F, Muller-Hocker J, Stehr M, von Schweinitz D, Kappler R. 2013. Selective methylation of CpGs at regulatory binding sites controls NNAT expression in Wilms tumors. PLoS ONE 8: e67605.
-
(2013)
Plos ONE
, vol.8
-
-
Hubertus, J.1
Zitzmann, F.2
Trippel, F.3
Muller-Hocker, J.4
Stehr, M.5
Von Schweinitz, D.6
Kappler, R.7
-
55
-
-
79151472081
-
Wilms’ tumours: About tumour suppressor genes, an oncogene and a chameleon gene
-
Huff V. 2011. Wilms’ tumours: about tumour suppressor genes, an oncogene and a chameleon gene. Nat Rev Cancer 11: 111–121.
-
(2011)
Nat Rev Cancer
, vol.11
, pp. 111-121
-
-
Huff, V.1
-
56
-
-
77956342464
-
MicroRNA-185 suppresses tumor growth and progression by targeting the Six1 oncogene in human cancers
-
Imam JS, Buddavarapu K, Lee-Chang JS, Ganapathy S, Camosy C, Chen Y, Rao MK. 2010. MicroRNA-185 suppresses tumor growth and progression by targeting the Six1 oncogene in human cancers. Oncogene 29: 4971–4979.
-
(2010)
Oncogene
, vol.29
, pp. 4971-4979
-
-
Imam, J.S.1
Buddavarapu, K.2
Lee-Chang, J.S.3
Ganapathy, S.4
Camosy, C.5
Chen, Y.6
Rao, M.K.7
-
57
-
-
77953277032
-
The Paf1 complex: Platform or player in RNA polymerase II transcription?
-
Jaehning JA. 2010. The Paf1 complex: platform or player in RNA polymerase II transcription?. Biochim Biophys Acta 1799: 379–388.
-
(2010)
Biochim Biophys Acta
, vol.1799
, pp. 379-388
-
-
Jaehning, J.A.1
-
58
-
-
58149157778
-
Germline mutations in WTX cause a sclerosing skeletal dysplasia but do not predispose to tumorigenesis
-
Jenkins ZA, van Kogelenberg M, Morgan T, Jeffs A, Fukuzawa R, Pearl E, Thaller C, Hing AV, Porteous ME, Garcia-Minaur S, et al. 2009. Germline mutations in WTX cause a sclerosing skeletal dysplasia but do not predispose to tumorigenesis. Nat Genet 41: 95–100.
-
(2009)
Nat Genet
, vol.41
, pp. 95-100
-
-
Jenkins, Z.A.1
Van Kogelenberg, M.2
Morgan, T.3
Jeffs, A.4
Fukuzawa, R.5
Pearl, E.6
Thaller, C.7
Hing, A.V.8
Porteous, M.E.9
Garcia-Minaur, S.10
-
59
-
-
0019638461
-
Interstitial deletion of short arm of chromosome 11 limited to Wilms’ tumor cells in a patient without aniridia
-
Kaneko Y, Egues MC, Rowley JD. 1981. Interstitial deletion of short arm of chromosome 11 limited to Wilms’ tumor cells in a patient without aniridia. Cancer Res 41: 4577–4578.
-
(1981)
Cancer Res
, vol.41
, pp. 4577-4578
-
-
Kaneko, Y.1
Egues, M.C.2
Rowley, J.D.3
-
60
-
-
79955155333
-
Canonical Wnt9b signaling balances progenitor cell expansion and differentiation during kidney development
-
Karner CM, Das A, Ma Z, Self M, Chen C, Lum L, Oliver G, Carroll TJ. 2011. Canonical Wnt9b signaling balances progenitor cell expansion and differentiation during kidney development. Development 138: 1247–1257.
-
(2011)
Development
, vol.138
, pp. 1247-1257
-
-
Karner, C.M.1
Das, A.2
Ma, Z.3
Self, M.4
Chen, C.5
Lum, L.6
Oliver, G.7
Carroll, T.J.8
-
61
-
-
77951986098
-
A novel Wilms tumor 1 (WT1) target gene negatively regulates the WNT signaling pathway
-
Kim MS, Yoon SK, Bollig F, Kitagaki J, Hur W, Whye NJ, Wu YP, Rivera MN, Park JY, Kim HS, et al. 2010. A novel Wilms tumor 1 (WT1) target gene negatively regulates the WNT signaling pathway. J Biol Chem 285: 14585–14593.
-
(2010)
J Biol Chem
, vol.285
, pp. 14585-14593
-
-
Kim, M.S.1
Yoon, S.K.2
Bollig, F.3
Kitagaki, J.4
Hur, W.5
Whye, N.J.6
Wu, Y.P.7
Rivera, M.N.8
Park, J.Y.9
Kim, H.S.10
-
62
-
-
84858047563
-
The WTX tumor suppressor enhances p53 acetylation by CBP/p300
-
Kim WJ, Rivera MN, Coffman EJ, Haber DA. 2012. The WTX tumor suppressor enhances p53 acetylation by CBP/p300. Mol Cell 45: 587–597.
-
(2012)
Mol Cell
, vol.45
, pp. 587-597
-
-
Kim, W.J.1
Rivera, M.N.2
Coffman, E.J.3
Haber, D.A.4
-
63
-
-
0031766557
-
Wnt-4 is a mesenchymal signal for epithelial transformation of metanephric mesenchyme in the developing kidney
-
Kispert A, Vainio S, McMahon AP. 1998. Wnt-4 is a mesenchymal signal for epithelial transformation of metanephric mesenchyme in the developing kidney. Development 125: 4225–4234.
-
(1998)
Development
, vol.125
, pp. 4225-4234
-
-
Kispert, A.1
Vainio, S.2
McMahon, A.P.3
-
64
-
-
0015295131
-
Mutation and cancer: A model for Wilms’ tumor of the kidney
-
Knudson AG Jr, Strong LC. 1972. Mutation and cancer: a model for Wilms’ tumor of the kidney. J Natl Cancer Inst 48: 313–324.
-
(1972)
J Natl Cancer Inst
, vol.48
, pp. 313-324
-
-
Knudson, A.G.1
Strong, L.C.2
-
65
-
-
48149095359
-
Six2 defines and regulates a multipotent self-renewing nephron progenitor population throughout mammalian kidney development
-
Kobayashi A, Valerius MT, Mugford JW, Carroll TJ, Self M, Oliver G, McMahon AP. 2008. Six2 defines and regulates a multipotent self-renewing nephron progenitor population throughout mammalian kidney development. Cell Stem Cell 3: 169–181.
-
(2008)
Cell Stem Cell
, vol.3
, pp. 169-181
-
-
Kobayashi, A.1
Valerius, M.T.2
Mugford, J.W.3
Carroll, T.J.4
Self, M.5
Oliver, G.6
McMahon, A.P.7
-
66
-
-
0033566764
-
Mutational activation of the b-catenin proto-oncogene is a common event in the development of Wilms’ tumors
-
Koesters R, Ridder R, Kopp-Schneider A, Betts D, Adams V, Niggli F, Briner J, von Knebel Doeberitz M. 1999. Mutational activation of the b-catenin proto-oncogene is a common event in the development of Wilms’ tumors. Cancer Res 59: 3880–3882.
-
(1999)
Cancer Res
, vol.59
, pp. 3880-3882
-
-
Koesters, R.1
Ridder, R.2
Kopp-Schneider, A.3
Betts, D.4
Adams, V.5
Niggli, F.6
Briner, J.7
Von Knebel Doeberitz, M.8
-
68
-
-
84879274130
-
Identification of the transcription factor HOXB4 as a novel target of miR-23a
-
Koller K, Das S, Leuschner I, Korbelius M, Hoefler G, Guertl B. 2013. Identification of the transcription factor HOXB4 as a novel target of miR-23a. Genes Chromosomes Cancer 52: 709–715.
-
(2013)
Genes Chromosomes Cancer
, vol.52
, pp. 709-715
-
-
Koller, K.1
Das, S.2
Leuschner, I.3
Korbelius, M.4
Hoefler, G.5
Guertl, B.6
-
69
-
-
49249108314
-
The E2F3–Oncomir-1 axis is activated in Wilms’ tumor
-
Kort EJ, Farber L, Tretiakova M, Petillo D, Furge KA, Yang XJ, Cornelius A, Teh BT. 2008. The E2F3–Oncomir-1 axis is activated in Wilms’ tumor. Cancer Res 68: 4034–4038.
-
(2008)
Cancer Res
, vol.68
, pp. 4034-4038
-
-
Kort, E.J.1
Farber, L.2
Tretiakova, M.3
Petillo, D.4
Furge, K.A.5
Yang, X.J.6
Cornelius, A.7
Teh, B.T.8
-
70
-
-
0024517062
-
Familial Wiedemann- Beckwith syndrome and a second Wilms tumor locus both map to 11p15.5
-
Koufos A, Grundy P, Morgan K, Aleck KA, Hadro T, Lampkin BC, Kalbakji A, Cavenee WK. 1989. Familial Wiedemann- Beckwith syndrome and a second Wilms tumor locus both map to 11p15.5. Am J Hum Genet 44: 711–719.
-
(1989)
Am J Hum Genet
, vol.44
, pp. 711-719
-
-
Koufos, A.1
Grundy, P.2
Morgan, K.3
Aleck, K.A.4
Hadro, T.5
Lampkin, B.C.6
Kalbakji, A.7
Cavenee, W.K.8
-
71
-
-
0027182741
-
WT-1 is required for early kidney development
-
Kreidberg JA, Sariola H, Loring JM, Maeda M, Pelletier J, Housman D, Jaenisch R. 1993. WT-1 is required for early kidney development. Cell 74: 679–691.
-
(1993)
Cell
, vol.74
, pp. 679-691
-
-
Kreidberg, J.A.1
Sariola, H.2
Loring, J.M.3
Maeda, M.4
Pelletier, J.5
Housman, D.6
Jaenisch, R.7
-
72
-
-
0036781630
-
Codon 45 of the b-catenin gene, a specific mutational target site of Wilms’ tumor
-
Kusafuka T, Miao J, Kuroda S, Udatsu Y, Yoneda A. 2002. Codon 45 of the b-catenin gene, a specific mutational target site of Wilms’ tumor. Int J Mol Med 10: 395–399.
-
(2002)
Int J Mol Med
, vol.10
, pp. 395-399
-
-
Kusafuka, T.1
Miao, J.2
Kuroda, S.3
Udatsu, Y.4
Yoneda, A.5
-
74
-
-
0029024277
-
Disruption of imprinting caused by deletion of the H19 gene region in mice
-
Leighton PA, Ingram RS, Eggenschwiler J, Efstratiadis A, Tilghman SM. 1995. Disruption of imprinting caused by deletion of the H19 gene region in mice. Nature 375: 34–39.
-
(1995)
Nature
, vol.375
, pp. 34-39
-
-
Leighton, P.A.1
Ingram, R.S.2
Eggenschwiler, J.3
Efstratiadis, A.4
Tilghman, S.M.5
-
75
-
-
0026457082
-
Aberrant expression of the tumour suppressor gene p53 is very frequent in Wilms’ tumours
-
Lemoine NR, Hughes CM, Cowell JK. 1992. Aberrant expression of the tumour suppressor gene p53 is very frequent in Wilms’ tumours. J Pathol 168: 237–242.
-
(1992)
J Pathol
, vol.168
, pp. 237-242
-
-
Lemoine, N.R.1
Hughes, C.M.2
Cowell, J.K.3
-
76
-
-
84883819602
-
Heritable gene targeting in themouse and rat using a CRISPR–Cas system
-
Li D, Qiu Z, Shao Y, Chen Y, Guan Y, Liu M, Li Y, Gao N, Wang L, Lu X, et al. 2013a. Heritable gene targeting in themouse and rat using a CRISPR–Cas system. Nat Biotechnol 31: 681–683.
-
(2013)
Nat Biotechnol
, vol.31
, pp. 681-683
-
-
Li, D.1
Qiu, Z.2
Shao, Y.3
Chen, Y.4
Guan, Y.5
Liu, M.6
Li, Y.7
Gao, N.8
Wang, L.9
Lu, X.10
-
77
-
-
84883779087
-
Simultaneous generation and germline transmission of multiple gene mutations in rat using CRISPR–Cas systems
-
Li W, Teng F, Li T, Zhou Q. 2013b. Simultaneous generation and germline transmission of multiple gene mutations in rat using CRISPR–Cas systems. Nat Biotechnol 31: 684–686.
-
(2013)
Nat Biotechnol
, vol.31
, pp. 684-686
-
-
Li, W.1
Teng, F.2
Li, T.3
Zhou, Q.4
-
78
-
-
84902827660
-
Efficient genetic manipulation of the NOD–Rag1_/_IL2RgCnull mouse by combining in vitro fertilization and CRISPR/Cas9 technology
-
Li F, Cowley DO, Banner D, Holle E, Zhang L, Su L. 2014a. Efficient genetic manipulation of the NOD–Rag1_/_IL2RgCnull mouse by combining in vitro fertilization and CRISPR/Cas9 technology. Sci Rep 4: 5290.
-
(2014)
Sci Rep
, vol.4
-
-
Li, F.1
Cowley, D.O.2
Banner, D.3
Holle, E.4
Zhang, L.5
Su, L.6
-
79
-
-
84902540456
-
Developmental origins and functions of stromal cells in the normal and diseased mammalian kidney
-
Li W, Hartwig S, Rosenblum ND. 2014b. Developmental origins and functions of stromal cells in the normal and diseased mammalian kidney. Dev Dyn 243: 853–863.
-
(2014)
Dev Dyn
, vol.243
, pp. 853-863
-
-
Li, W.1
Hartwig, S.2
Rosenblum, N.D.3
-
80
-
-
84892942429
-
Live pigs produced from genome edited zygotes
-
Lillico SG, Proudfoot C, Carlson DF, Stverakova D, Neil C, Blain C, King TJ, Ritchie WA, Tan W, Mileham AJ, et al. 2013. Live pigs produced from genome edited zygotes. Sci Rep 3: 2847.
-
(2013)
Sci Rep
, vol.3
-
-
Lillico, S.G.1
Proudfoot, C.2
Carlson, D.F.3
Stverakova, D.4
Neil, C.5
Blain, C.6
King, T.J.7
Ritchie, W.A.8
Tan, W.9
Mileham, A.J.10
-
81
-
-
84871060325
-
Global demethylation in loss of imprinting subtype of Wilms tumor
-
Ludgate JL, Le Mee G, Fukuzawa R, Rodger EJ, Weeks RJ, Reeve AE, Morison IM. 2013. Global demethylation in loss of imprinting subtype of Wilms tumor. Genes Chromosomes Cancer 52: 174–184.
-
(2013)
Genes Chromosomes Cancer
, vol.52
, pp. 174-184
-
-
Ludgate, J.L.1
Le Mee, G.2
Fukuzawa, R.3
Rodger, E.J.4
Weeks, R.J.5
Reeve, A.E.6
Morison, I.M.7
-
82
-
-
0033677022
-
Frequent association of b-catenin and WT1 mutations in Wilms tumors
-
Maiti S, Alam R, Amos CI, Huff V. 2000. Frequent association of b-catenin and WT1 mutations in Wilms tumors. Cancer Res 60: 6288–6292.
-
(2000)
Cancer Res
, vol.60
, pp. 6288-6292
-
-
Maiti, S.1
Alam, R.2
Amos, C.I.3
Huff, V.4
-
83
-
-
34249061491
-
Wilms tumor suppressor WTX negatively regulates WNT/b-catenin signaling
-
Major MB, Camp ND, Berndt JD, Yi X, Goldenberg SJ, Hubbert C, Biechele TL, Gingras AC, Zheng N, Maccoss MJ, et al. 2007. Wilms tumor suppressor WTX negatively regulates WNT/b-catenin signaling. Science 316: 1043–1046.
-
(2007)
Science
, vol.316
, pp. 1043-1046
-
-
Major, M.B.1
Camp, N.D.2
Berndt, J.D.3
Yi, X.4
Goldenberg, S.J.5
Hubbert, C.6
Biechele, T.L.7
Gingras, A.C.8
Zheng, N.9
Maccoss, M.J.10
-
84
-
-
84907963100
-
TP53 mutational status is a potential marker for risk stratification in Wilms tumour with diffuse anaplasia
-
e109924
-
Maschietto M, Williams RD, Chagtai T, Popov SD, Sebire NJ, Vujanic G, Perlman E, Anderson JR, Grundy P, Dome JS, et al. 2014. TP53 mutational status is a potential marker for risk stratification in Wilms tumour with diffuse anaplasia. PLoS ONE 9: e109924.
-
(2014)
Plos ONE
, vol.9
-
-
Maschietto, M.1
Williams, R.D.2
Chagtai, T.3
Popov, S.D.4
Sebire, N.J.5
Vujanic, G.6
Perlman, E.7
Erson, J.R.8
Grundy, P.9
Dome, J.S.10
-
85
-
-
0042524183
-
The wt1-heterozygous mouse; a model to study the development of glomerular sclerosis
-
Menke AL, IJpenberg A, Fleming S, Ross A, Medine CN, Patek CE, Spraggon L, Hughes J, Clarke AR, Hastie ND. 2003. The wt1-heterozygous mouse; a model to study the development of glomerular sclerosis. J Pathol 200: 667–674.
-
(2003)
J Pathol
, vol.200
, pp. 667-674
-
-
Menke, A.L.1
Ijpenberg, A.2
Fleming, S.3
Ross, A.4
Medine, C.N.5
Patek, C.E.6
Spraggon, L.7
Hughes, J.8
Clarke, A.R.9
Hastie, N.D.10
-
86
-
-
53649093784
-
Accumulation of malignant renal stem cells is associated with epigenetic changes in normal renal progenitor genes
-
Metsuyanim S, Pode-Shakked N, Schmidt-Ott KM, Keshet G, Rechavi G, Blumental D, Dekel B. 2008. Accumulation of malignant renal stem cells is associated with epigenetic changes in normal renal progenitor genes. Stem Cells 26: 1808–1817.
-
(2008)
Stem Cells
, vol.26
, pp. 1808-1817
-
-
Metsuyanim, S.1
Pode-Shakked, N.2
Schmidt-Ott, K.M.3
Keshet, G.4
Rechavi, G.5
Blumental, D.6
Dekel, B.7
-
87
-
-
69249219272
-
Expression of stem cell markers in the human fetal kidney
-
e6709
-
Metsuyanim S, Harari-Steinberg O, Buzhor E, Omer D, Pode-Shakked N, Ben-Hur H, Halperin R, Schneider D, Dekel B. 2009. Expression of stem cell markers in the human fetal kidney. PLoS ONE 4: e6709.
-
(2009)
Plos ONE
, vol.4
-
-
Metsuyanim, S.1
Harari-Steinberg, O.2
Buzhor, E.3
Omer, D.4
Pode-Shakked, N.5
Ben-Hur, H.6
Halperin, R.7
Schneider, D.8
Dekel, B.9
-
88
-
-
82755163767
-
WT1 in disease: Shifting the epithelial–mesenchymal balance
-
Miller-Hodges E, Hohenstein P. 2012. WT1 in disease: shifting the epithelial–mesenchymal balance. J Pathol 226: 229–240.
-
(2012)
J Pathol
, vol.226
, pp. 229-240
-
-
Miller-Hodges, E.1
Hohenstein, P.2
-
89
-
-
0031611708
-
Loss of WT1 function leads to ectopic myogenesis in Wilms’ tumour
-
Miyagawa K, Kent J, Moore A, Charlieu JP, Little MH, Williamson KA, Kelsey A, Brown KW, Hassam S, Briner J, et al. 1998. Loss of WT1 function leads to ectopic myogenesis in Wilms’ tumour. Nat Genet 18: 15–17.
-
(1998)
Nat Genet
, vol.18
, pp. 15-17
-
-
Miyagawa, K.1
Kent, J.2
Moore, A.3
Charlieu, J.P.4
Little, M.H.5
Williamson, K.A.6
Kelsey, A.7
Brown, K.W.8
Hassam, S.9
Briner, J.10
-
90
-
-
79955908615
-
The WTX tumor suppressor regulates mesenchymal progenitor cell fate specification
-
Moisan A, Rivera MN, Lotinun S, Akhavanfard S, Coffman EJ, Cook EB, Stoykova S, Mukherjee S, Schoonmaker JA, Burger A, et al. 2011. The WTX tumor suppressor regulates mesenchymal progenitor cell fate specification. Dev Cell 20: 583–596.
-
(2011)
Dev Cell
, vol.20
, pp. 583-596
-
-
Moisan, A.1
Rivera, M.N.2
Lotinun, S.3
Akhavanfard, S.4
Coffman, E.J.5
Cook, E.B.6
Stoykova, S.7
Mukherjee, S.8
Schoonmaker, J.A.9
Burger, A.10
-
91
-
-
0242437939
-
Multigene methylation analysis of Wilms’ tumour and adult renal cell carcinoma
-
Morris MR, Hesson LB, Wagner KJ, Morgan NV, Astuti D, Lees RD, Cooper WN, Lee J, Gentle D, Macdonald F, et al. 2003. Multigene methylation analysis of Wilms’ tumour and adult renal cell carcinoma. Oncogene 22: 6794–6801.
-
(2003)
Oncogene
, vol.22
, pp. 6794-6801
-
-
Morris, M.R.1
Hesson, L.B.2
Wagner, K.J.3
Morgan, N.V.4
Astuti, D.5
Lees, R.D.6
Cooper, W.N.7
Lee, J.8
Gentle, D.9
Macdonald, F.10
-
92
-
-
0024095742
-
N-myc proto-oncogene expression during organogenesis in the developing mouse as revealed by in situ hybridization
-
Mugrauer G, Alt FW, Ekblom P. 1988. N-myc proto-oncogene expression during organogenesis in the developing mouse as revealed by in situ hybridization. J Cell Biol 107: 1325–1335.
-
(1988)
J Cell Biol
, vol.107
, pp. 1325-1335
-
-
Mugrauer, G.1
Alt, F.W.2
Ekblom, P.3
-
93
-
-
84890863499
-
Aberrant activation, nuclear localization, and phosphorylation of Yes-associated protein-1 in the embryonic kidney and Wilms tumor
-
Murphy AJ, Pierce J, de Caestecker C, Libes J, Neblett D, de Caestecker M, Perantoni AO, Tanigawa S, Anderson JR, Dome JS, et al. 2014. Aberrant activation, nuclear localization, and phosphorylation of Yes-associated protein-1 in the embryonic kidney and Wilms tumor. Pediatr Blood Cancer 61: 198–205.
-
(2014)
Pediatr Blood Cancer
, vol.61
, pp. 198-205
-
-
Murphy, A.J.1
Pierce, J.2
De Caestecker, C.3
Libes, J.4
Neblett, D.5
De Caestecker, M.6
Perantoni, A.O.7
Tanigawa, S.8
Erson, J.R.9
Dome, J.S.10
-
94
-
-
78651387406
-
Dicer regulates the development of nephrogenic and ureteric compartments in the mammalian kidney
-
Nagalakshmi VK, Ren Q, Pugh MM, Valerius MT, McMahon AP, Yu J. 2011. Dicer regulates the development of nephrogenic and ureteric compartments in the mammalian kidney. Kidney Int 79: 317–330.
-
(2011)
Kidney Int
, vol.79
, pp. 317-330
-
-
Nagalakshmi, V.K.1
Ren, Q.2
Pugh, M.M.3
Valerius, M.T.4
McMahon, A.P.5
Yu, J.6
-
95
-
-
0022848633
-
Enhanced expression of the N-myc gene in Wilms’ tumors
-
Nisen PD, Zimmerman KA, Cotter SV, Gilbert F, Alt FW. 1986. Enhanced expression of the N-myc gene in Wilms’ tumors. Cancer Res 46: 6217–6222.
-
(1986)
Cancer Res
, vol.46
, pp. 6217-6222
-
-
Nisen, P.D.1
Zimmerman, K.A.2
Cotter, S.V.3
Gilbert, F.4
Alt, F.W.5
-
96
-
-
28844450700
-
Both hypomethylation and hypermethylation in a 0.2-kb region of a DNA repeat in cancer
-
Nishiyama R, Qi L, Lacey M, Ehrlich M. 2005. Both hypomethylation and hypermethylation in a 0.2-kb region of a DNA repeat in cancer. Mol Cancer Res 3: 617–626.
-
(2005)
Mol Cancer Res
, vol.3
, pp. 617-626
-
-
Nishiyama, R.1
Qi, L.2
Lacey, M.3
Ehrlich, M.4
-
98
-
-
0027285258
-
Relaxation of insulin-like growth factor II gene imprinting implicated in Wilms’ tumour
-
Ogawa O, Eccles MR, Szeto J, McNoe LA, Yun K, Maw MA, Smith PJ, Reeve AE. 1993. Relaxation of insulin-like growth factor II gene imprinting implicated in Wilms’ tumour. Nature 362: 749–751.
-
(1993)
Nature
, vol.362
, pp. 749-751
-
-
Ogawa, O.1
Eccles, M.R.2
Szeto, J.3
McNoe, L.A.4
Yun, K.5
Maw, M.A.6
Smith, P.J.7
Reeve, A.E.8
-
99
-
-
0033566704
-
Mosaic allelic insulin-like growth factor 2 expression patterns reveal a link between Wilms’ tumorigenesis and epigenetic heterogeneity
-
Ohlsson R, Cui H, He L, Pfeifer S, Malmikumpu H, Jiang S, Feinberg AP, Hedborg F. 1999. Mosaic allelic insulin-like growth factor 2 expression patterns reveal a link between Wilms’ tumorigenesis and epigenetic heterogeneity. Cancer Res 59: 3889–3892.
-
(1999)
Cancer Res
, vol.59
, pp. 3889-3892
-
-
Ohlsson, R.1
Cui, H.2
He, L.3
Pfeifer, S.4
Malmikumpu, H.5
Jiang, S.6
Feinberg, A.P.7
Hedborg, F.8
-
100
-
-
84894109473
-
Premature termination of reprogramming in vivo leads to cancer development through altered epigenetic regulation
-
Ohnishi K, Semi K, Yamamoto T, Shimizu M, Tanaka A, Mitsunaga K, Okita K, Osafune K, Arioka Y, Maeda T, et al. 2014. Premature termination of reprogramming in vivo leads to cancer development through altered epigenetic regulation. Cell 156: 663–677.
-
(2014)
Cell
, vol.156
, pp. 663-677
-
-
Ohnishi, K.1
Semi, K.2
Yamamoto, T.3
Shimizu, M.4
Tanaka, A.5
Mitsunaga, K.6
Okita, K.7
Osafune, K.8
Arioka, Y.9
Maeda, T.10
-
101
-
-
84863860170
-
Methylation of the RASSF1A promoter is predictive of poor outcome among patients with Wilms tumor
-
Ohshima J, Haruta M, Fujiwara Y, Watanabe N, Arai Y, Ariga T, Okita H, Koshinaga T, Oue T, Hinotsu S, et al. 2012. Methylation of the RASSF1A promoter is predictive of poor outcome among patients with Wilms tumor. Pediatr Blood Cancer 59: 499–505.
-
(2012)
Pediatr Blood Cancer
, vol.59
, pp. 499-505
-
-
Ohshima, J.1
Haruta, M.2
Fujiwara, Y.3
Watanabe, N.4
Arai, Y.5
Ariga, T.6
Okita, H.7
Koshinaga, T.8
Oue, T.9
Hinotsu, S.10
-
102
-
-
18744418115
-
Expression and imprinting status of human PEG8/IGF2AS, a paternally expressed antisense transcript from the IGF2 locus, in Wilms’ tumors
-
Okutsu T, Kuroiwa Y, Kagitani F, Kai M, Aisaka K, Tsutsumi O, Kaneko Y, Yokomori K, Surani MA, Kohda T, et al. 2000. Expression and imprinting status of human PEG8/IGF2AS, a paternally expressed antisense transcript from the IGF2 locus, in Wilms’ tumors. J Biochem 127: 475–483.
-
(2000)
J Biochem
, vol.127
, pp. 475-483
-
-
Okutsu, T.1
Kuroiwa, Y.2
Kagitani, F.3
Kai, M.4
Aisaka, K.5
Tsutsumi, O.6
Kaneko, Y.7
Yokomori, K.8
Surani, M.A.9
Kohda, T.10
-
103
-
-
84896708412
-
Wt1 in the kidney—a tale in mouse models
-
Ozdemir DD, Hohenstein P. 2014. Wt1 in the kidney—a tale in mouse models. Pediatr Nephrol 29: 687–693.
-
(2014)
Pediatr Nephrol
, vol.29
, pp. 687-693
-
-
Ozdemir, D.D.1
Hohenstein, P.2
-
104
-
-
0027379032
-
Inactivation of WT1 in nephrogenic rests, genetic precursors to Wilms’ tumour
-
Park S, Bernard A, Bove KE, Sens DA, Hazen-Martin DJ, Garvin AJ, Haber DA. 1993. Inactivation of WT1 in nephrogenic rests, genetic precursors to Wilms’ tumour. Nat Genet 5: 363–367.
-
(1993)
Nat Genet
, vol.5
, pp. 363-367
-
-
Park, S.1
Bernard, A.2
Bove, K.E.3
Sens, D.A.4
Hazen-Martin, D.J.5
Garvin, A.J.6
Haber, D.A.7
-
105
-
-
84866013368
-
Six2 and Wnt regulate self-renewal and commitment of nephron progenitors through shared gene regulatory networks
-
Park JS, Ma W, O’Brien LL, Chung E, Guo JJ, Cheng JG, Valerius MT, McMahon JA, Wong WH, McMahon AP. 2012. Six2 and Wnt regulate self-renewal and commitment of nephron progenitors through shared gene regulatory networks. Dev Cell 23: 637–651.
-
(2012)
Dev Cell
, vol.23
, pp. 637-651
-
-
Park, J.S.1
Ma, W.2
O’Brien, L.L.3
Chung, E.4
Guo, J.J.5
Cheng, J.G.6
Valerius, M.T.7
McMahon, J.A.8
Wong, W.H.9
McMahon, A.P.10
-
106
-
-
84907228025
-
Targeted gene knockout in chickens mediated by TALENs
-
Park TS, Lee HJ, Kim KH, Kim JS, Han JY. 2014. Targeted gene knockout in chickens mediated by TALENs. Proc Natl Acad Sci 111: 12716–12721.
-
(2014)
Proc Natl Acad Sci
, vol.111
, pp. 12716-12721
-
-
Park, T.S.1
Lee, H.J.2
Kim, K.H.3
Kim, J.S.4
Han, J.Y.5
-
107
-
-
0026094584
-
Germline mutations in the Wilms’ tumor suppressor gene are associated with abnormal urogenital development in Denys-Drash syndrome
-
Pelletier J, Bruening W, Kashtan CE, Mauer SM, Manivel JC, Striegel JE, Houghton DC, Junien C, Habib R, Fouser L, et al. 1991. Germline mutations in the Wilms’ tumor suppressor gene are associated with abnormal urogenital development in Denys-Drash syndrome. Cell 67: 437–447.
-
(1991)
Cell
, vol.67
, pp. 437-447
-
-
Pelletier, J.1
Bruening, W.2
Kashtan, C.E.3
Mauer, S.M.4
Manivel, J.C.5
Striegel, J.E.6
Houghton, D.C.7
Junien, C.8
Habib, R.9
Fouser, L.10
-
108
-
-
84890518697
-
Is Wilms tumor a candidate neoplasia for treatment with WNT/b-catenin pathway modulators?—A report from the renal tumors biology-driven drug development workshop
-
Perotti D, Hohenstein P, Bongarzone I, Maschietto M, Weeks M, Radice P, Pritchard-Jones K. 2013. Is Wilms tumor a candidate neoplasia for treatment with WNT/b-catenin pathway modulators?—A report from the renal tumors biology-driven drug development workshop. Mol Cancer Ther 12: 2619–2627.
-
(2013)
Mol Cancer Ther
, vol.12
, pp. 2619-2627
-
-
Perotti, D.1
Hohenstein, P.2
Bongarzone, I.3
Maschietto, M.4
Weeks, M.5
Radice, P.6
Pritchard-Jones, K.7
-
109
-
-
80052301382
-
Wilms tumor–a renal stem cell malignancy?
-
Pode-Shakked N, Dekel B. 2011. Wilms tumor–a renal stem cell malignancy? Pediatr Nephrol 26: 1535–1543.
-
(2011)
Pediatr Nephrol
, vol.26
, pp. 1535-1543
-
-
Pode-Shakked, N.1
Dekel, B.2
-
110
-
-
84871940855
-
The isolation and characterization of renal cancer initiating cells from human Wilms’ tumour xenografts unveils new therapeutic targets
-
Pode-Shakked N, Shukrun R, Mark-Danieli M, Tsvetkov P, Bahar S, Pri-Chen S, Goldstein RS, Rom-Gross E, Mor Y, Fridman E, et al. 2013. The isolation and characterization of renal cancer initiating cells from human Wilms’ tumour xenografts unveils new therapeutic targets. EMBOMolMed 5: 18–37.
-
(2013)
Embomolmed
, vol.5
, pp. 18-37
-
-
Pode-Shakked, N.1
Shukrun, R.2
Mark-Danieli, M.3
Tsvetkov, P.4
Bahar, S.5
Pri-Chen, S.6
Goldstein, R.S.7
Rom-Gross, E.8
Mor, Y.9
Fridman, E.10
-
111
-
-
69549122361
-
Interplay between activin and Hox genes determines the formation of the kidney morphogenetic field
-
Preger-Ben Noon E, Barak H, Guttmann-Raviv N, Reshef R. 2009. Interplay between activin and Hox genes determines the formation of the kidney morphogenetic field. Development 136: 1995–2004.
-
(2009)
Development
, vol.136
, pp. 1995-2004
-
-
Preger-Ben Noon, E.1
Barak, H.2
Guttmann-Raviv, N.3
Reshef, R.4
-
112
-
-
0025291908
-
The candidate Wilms’ tumour gene is involved in genitourinary development
-
Pritchard-Jones K, Fleming S, Davidson D, Bickmore W, Porteous D, Gosden C, Bard J, Buckler A, Pelletier J, Housman D, et al. 1990. The candidate Wilms’ tumour gene is involved in genitourinary development. Nature 346: 194–197.
-
(1990)
Nature
, vol.346
, pp. 194-197
-
-
Pritchard-Jones, K.1
Fleming, S.2
Davidson, D.3
Bickmore, W.4
Porteous, D.5
Gosden, C.6
Bard, J.7
Buckler, A.8
Pelletier, J.9
Housman, D.10
-
113
-
-
80052758645
-
A resource of vectors and ES cells for targeted deletion of microRNAs in mice
-
Prosser HM, Koike-Yusa H, Cooper JD, Law FC, Bradley A. 2011. A resource of vectors and ES cells for targeted deletion of microRNAs in mice. Nat Biotechnol 29: 840–845.
-
(2011)
Nat Biotechnol
, vol.29
, pp. 840-845
-
-
Prosser, H.M.1
Koike-Yusa, H.2
Cooper, J.D.3
Law, F.C.4
Bradley, A.5
-
114
-
-
84922792031
-
Somatic mutations in DROSHA and DICER1 impair micro- RNA biogenesis through distinct mechanisms in Wilms tumours
-
Rakheja D, Chen KS, Liu Y, Shukla AA, Schmid V, Chang TC, Khokhar S, Wickiser JE, Karandikar NJ, Malter JS, et al. 2014. Somatic mutations in DROSHA and DICER1 impair micro- RNA biogenesis through distinct mechanisms in Wilms tumours. Nat Commun 2: 4802.
-
(2014)
Nat Commun
, vol.2
-
-
Rakheja, D.1
Chen, K.S.2
Liu, Y.3
Shukla, A.A.4
Schmid, V.5
Chang, T.C.6
Khokhar, S.7
Wickiser, J.E.8
Karandikar, N.J.9
Malter, J.S.10
-
115
-
-
0030993133
-
Deletion of the H19 transcription unit reveals the existence of a putative imprinting control element
-
Ripoche MA, Kress C, Poirier F, Dandolo L. 1997. Deletion of the H19 transcription unit reveals the existence of a putative imprinting control element. Genes Dev 11: 1596–1604.
-
(1997)
Genes Dev
, vol.11
, pp. 1596-1604
-
-
Ripoche, M.A.1
Kress, C.2
Poirier, F.3
Dandolo, L.4
-
116
-
-
33846846526
-
An X chromosome gene, WTX, is commonly inactivated in Wilms tumor
-
Rivera MN, Kim WJ, Wells J, Driscoll DR, Brannigan BW, Han M, Kim JC, Feinberg AP, Gerald WL, Vargas SO, et al. 2007. An X chromosome gene, WTX, is commonly inactivated in Wilms tumor. Science 315: 642–645.
-
(2007)
Science
, vol.315
, pp. 642-645
-
-
Rivera, M.N.1
Kim, W.J.2
Wells, J.3
Driscoll, D.R.4
Brannigan, B.W.5
Han, M.6
Kim, J.C.7
Feinberg, A.P.8
Gerald, W.L.9
Vargas, S.O.10
-
117
-
-
66249117651
-
The tumor suppressor WTX shuttles to the nucleus and modulates WT1 activity
-
Rivera MN, Kim WJ, Wells J, Stone A, Burger A, Coffman EJ, Zhang J, Haber DA. 2009. The tumor suppressor WTX shuttles to the nucleus and modulates WT1 activity. Proc Natl Acad Sci 106: 8338–8343.
-
(2009)
Proc Natl Acad Sci
, vol.106
, pp. 8338-8343
-
-
Rivera, M.N.1
Kim, W.J.2
Wells, J.3
Stone, A.4
Burger, A.5
Coffman, E.J.6
Zhang, J.7
Haber, D.A.8
-
118
-
-
43049157909
-
Wilms tumor genetics: Mutations in WT1, WTX, and CTNNB1 account for only about one-third of tumors
-
Ruteshouser EC, Robinson SM, Huff V. 2008. Wilms tumor genetics: mutations in WT1, WTX, and CTNNB1 account for only about one-third of tumors. Genes Chromosomes Cancer 47: 461–470.
-
(2008)
Genes Chromosomes Cancer
, vol.47
, pp. 461-470
-
-
Ruteshouser, E.C.1
Robinson, S.M.2
Huff, V.3
-
119
-
-
72049101514
-
El-Dahr SS. 2009. p53 regulates metanephric development
-
Saifudeen Z, Dipp S, Stefkova J, Yao X, Lookabaugh S, El-Dahr SS. 2009. p53 regulates metanephric development. J Am Soc Nephrol 20: 2328–2337.
-
J am Soc Nephrol
, vol.20
, pp. 2328-2337
-
-
Saifudeen, Z.1
Dipp, S.2
Stefkova, J.3
Yao, X.4
Lookabaugh, S.5
-
120
-
-
85027953823
-
Glomerular development—shaping the multi-cellular filtration unit
-
Schell C, Wanner N, Huber TB. 2014. Glomerular development—shaping the multi-cellular filtration unit. Semin Cell Dev Biol 36: 39–49.
-
(2014)
Semin Cell Dev Biol
, vol.36
, pp. 39-49
-
-
Schell, C.1
Wanner, N.2
Huber, T.B.3
-
121
-
-
0026363005
-
Loss of heterozygosity in non-tumoral tissue in two children with Beckwith-Wiedemann syndrome
-
Schneid H, Vazquez MP, Seurin D, le Bouc Y. 1991. Loss of heterozygosity in non-tumoral tissue in two children with Beckwith-Wiedemann syndrome. Growth Regul 1: 168–170.
-
(1991)
Growth Regul
, vol.1
, pp. 168-170
-
-
Schneid, H.1
Vazquez, M.P.2
Seurin, D.3
Le Bouc, Y.4
-
122
-
-
0023256838
-
Nonrandom loss of maternal chromosome 11 alleles in Wilms tumors
-
Schroeder WT, Chao LY, Dao DD, Strong LC, Pathak S, Riccardi V, Lewis WH, Saunders GF. 1987. Nonrandom loss of maternal chromosome 11 alleles in Wilms tumors. Am J Hum Genet 40: 413–420.
-
(1987)
Am J Hum Genet
, vol.40
, pp. 413-420
-
-
Schroeder, W.T.1
Chao, L.Y.2
Dao, D.D.3
Strong, L.C.4
Pathak, S.5
Riccardi, V.6
Lewis, W.H.7
Saunders, G.F.8
-
123
-
-
0030889197
-
Correlation of germ-line mutations and two-hit inactivation of the WT1 gene with Wilms tumors of stromal-predominant histology
-
Schumacher V, Schneider S, Figge A, Wildhardt G, Harms D, Schmidt D, Weirich A, Ludwig R, Royer-Pokora B. 1997. Correlation of germ-line mutations and two-hit inactivation of the WT1 gene with Wilms tumors of stromal-predominant histology. Proc Natl Acad Sci 94: 3972–3977.
-
(1997)
Proc Natl Acad Sci
, vol.94
, pp. 3972-3977
-
-
Schumacher, V.1
Schneider, S.2
Figge, A.3
Wildhardt, G.4
Harms, D.5
Schmidt, D.6
Weirich, A.7
Ludwig, R.8
Royer-Pokora, B.9
-
124
-
-
0037501301
-
Two molecular subgroups of Wilms’ tumors with or without WT1 mutations
-
Schumacher V, Schuhen S, Sonner S, Weirich A, Leuschner I, Harms D, Licht J, Roberts S, Royer-Pokora B. 2003. Two molecular subgroups of Wilms’ tumors with or without WT1 mutations. Clin Cancer Res 9: 2005–2014.
-
(2003)
Clin Cancer Res
, vol.9
, pp. 2005-2014
-
-
Schumacher, V.1
Schuhen, S.2
Sonner, S.3
Weirich, A.4
Leuschner, I.5
Harms, D.6
Licht, J.7
Roberts, S.8
Royer-Pokora, B.9
-
125
-
-
0022414038
-
Insulin-like growth factor-II gene expression in Wilms’ tumour and embryonic tissues
-
Scott J, Cowell J, Robertson ME, Priestley LM, Wadey R, Hopkins B, Pritchard J, Bell GI, Rall LB, Graham CF, et al. 1985. Insulin-like growth factor-II gene expression in Wilms’ tumour and embryonic tissues. Nature 317: 260–262.
-
(1985)
Nature
, vol.317
, pp. 260-262
-
-
Scott, J.1
Cowell, J.2
Robertson, M.E.3
Priestley, L.M.4
Wadey, R.5
Hopkins, B.6
Pritchard, J.7
Bell, G.I.8
Rall, L.B.9
Graham, C.F.10
-
126
-
-
33750455113
-
Six2 is required for suppression of nephrogenesis and progenitor renewal in the developing kidney
-
Self M, Lagutin OV, Bowling B, Hendrix J, Cai Y, Dressler GR, Oliver G. 2006. Six2 is required for suppression of nephrogenesis and progenitor renewal in the developing kidney. EMBO J 25: 5214–5228.
-
(2006)
EMBO J
, vol.25
, pp. 5214-5228
-
-
Self, M.1
Lagutin, O.V.2
Bowling, B.3
Hendrix, J.4
Cai, Y.5
Dressler, G.R.6
Oliver, G.7
-
127
-
-
84860488299
-
Guertl B. 2012. miR-192, miR-194, miR-215, miR-200c and miR-141 are downregulated and their common target ACVR2B is strongly expressed in renal childhood neoplasms
-
Senanayake U, Das S, Vesely P, Alzoughbi W, Frohlich LF, Chowdhury P, Leuschner I, Hoefler G, Guertl B. 2012. miR-192, miR-194, miR-215, miR-200c and miR-141 are downregulated and their common target ACVR2B is strongly expressed in renal childhood neoplasms. Carcinogenesis 33: 1014–1021.
-
Carcinogenesis
, vol.33
, pp. 1014-1021
-
-
Senanayake, U.1
Das, S.2
Vesely, P.3
Alzoughbi, W.4
Frohlich, L.F.5
Chowdhury, P.6
Leuschner, I.7
Hoefler, G.8
-
128
-
-
0028114299
-
A rodent model for Wilms tumors: Embryonal kidney neoplasms induced by N-nitroso-N9-methylurea
-
Sharma PM, Bowman M, Yu BF, Sukumar S. 1994. A rodent model for Wilms tumors: embryonal kidney neoplasms induced by N-nitroso-N9-methylurea. Proc Natl Acad Sci 91: 9931–9935.
-
(1994)
Proc Natl Acad Sci
, vol.91
, pp. 9931-9935
-
-
Sharma, P.M.1
Bowman, M.2
Yu, B.F.3
Sukumar, S.4
-
129
-
-
19944415836
-
Aberrant methylation of HIN-1 (High in normal-1) is a frequent event in many human malignancies
-
Shigematsu H, Suzuki M, Takahashi T, Miyajima K, Toyooka S, Shivapurkar N, Tomlinson GE, Mastrangelo D, Pass HI, Brambilla E, et al. 2005. Aberrant methylation of HIN-1 (high in normal-1) is a frequent event in many human malignancies. Int J Cancer 113: 600–604.
-
(2005)
Int J Cancer
, vol.113
, pp. 600-604
-
-
Shigematsu, H.1
Suzuki, M.2
Takahashi, T.3
Miyajima, K.4
Toyooka, S.5
Shivapurkar, N.6
Tomlinson, G.E.7
Mastrangelo, D.8
Pass, H.I.9
Brambilla, E.10
-
130
-
-
84904263575
-
Wilms’ tumor blastemal stem cells dedifferentiate to propagate the tumor bulk
-
Shukrun R, Pode-Shakked N, Pleniceanu O, Omer D, Vax E, Peer E, Pri-Chen S, Jacob J, Hu Q, Harari-Steinberg O, et al. 2014. Wilms’ tumor blastemal stem cells dedifferentiate to propagate the tumor bulk. Stem Cell Reports 3: 24–33.
-
(2014)
Stem Cell Reports
, vol.3
, pp. 24-33
-
-
Shukrun, R.1
Pode-Shakked, N.2
Pleniceanu, O.3
Omer, D.4
Vax, E.5
Peer, E.6
Pri-Chen, S.7
Jacob, J.8
Hu, Q.9
Harari-Steinberg, O.10
-
131
-
-
79953699619
-
DICER1 syndrome: Clarifying the diagnosis, clinical features and management implications of a pleiotropic tumour predisposition syndrome
-
Slade I, Bacchelli C, Davies H, Murray A, Abbaszadeh F, Hanks S, Barfoot R, Burke A, Chisholm J, Hewitt M, et al. 2011. DICER1 syndrome: clarifying the diagnosis, clinical features and management implications of a pleiotropic tumour predisposition syndrome. J Med Genet 48: 273–278.
-
(2011)
J Med Genet
, vol.48
, pp. 273-278
-
-
Slade, I.1
Bacchelli, C.2
Davies, H.3
Murray, A.4
Abbaszadeh, F.5
Hanks, S.6
Barfoot, R.7
Burke, A.8
Chisholm, J.9
Hewitt, M.10
-
133
-
-
0028588919
-
Epithelial transformation of metanephric mesenchyme in the developing kidney regulated by Wnt-4
-
Stark K, Vainio S, Vassileva G, McMahon AP. 1994. Epithelial transformation of metanephric mesenchyme in the developing kidney regulated by Wnt-4. Nature 372: 679–683.
-
(1994)
Nature
, vol.372
, pp. 679-683
-
-
Stark, K.1
Vainio, S.2
Vassileva, G.3
McMahon, A.P.4
-
134
-
-
84875340771
-
Widespread resetting of DNA methylation in glioblastoma- initiating cells suppresses malignant cellular behavior in a lineage-dependent manner
-
Stricker SH, Feber A, Engstrom PG, Caren H, Kurian KM, Takashima Y, Watts C, Way M, Dirks P, Bertone P, et al. 2013. Widespread resetting of DNA methylation in glioblastoma- initiating cells suppresses malignant cellular behavior in a lineage-dependent manner. Genes Dev 27: 654–669.
-
(2013)
Genes Dev
, vol.27
, pp. 654-669
-
-
Stricker, S.H.1
Feber, A.2
Engstrom, P.G.3
Caren, H.4
Kurian, K.M.5
Takashima, Y.6
Watts, C.7
Way, M.8
Dirks, P.9
Bertone, P.10
-
135
-
-
0030735169
-
Transactivation of Igf2 in a mouse model of Beckwith-Wiedemann syndrome
-
Sun FL, Dean WL, Kelsey G, Allen ND, Reik W. 1997. Transactivation of Igf2 in a mouse model of Beckwith-Wiedemann syndrome. Nature 389: 809–815.
-
(1997)
Nature
, vol.389
, pp. 809-815
-
-
Sun, F.L.1
Dean, W.L.2
Kelsey, G.3
Allen, N.D.4
Reik, W.5
-
136
-
-
84871257372
-
Control of epigenetic states by WT1 via regulation of de novo DNA methyltransferase 3A
-
Szemes M, Dallosso AR, Melegh Z, Curry T, Li Y, Rivers C, Uney J, Magdefrau AS, Schwiderski K, Park JH, et al. 2013. Control of epigenetic states by WT1 via regulation of de novo DNA methyltransferase 3A. Hum Mol Genet 22: 74–83.
-
(2013)
Hum Mol Genet
, vol.22
, pp. 74-83
-
-
Szemes, M.1
Dallosso, A.R.2
Melegh, Z.3
Curry, T.4
Li, Y.5
Rivers, C.6
Uney, J.7
Magdefrau, A.S.8
Schwiderski, K.9
Park, J.H.10
-
137
-
-
84866597456
-
Lin28-mediated control of let-7 microRNA expression by alternative TUTases Zcchc11 (TUT4) and Zcchc6 (TUT7)
-
Thornton JE, Chang HM, Piskounova E, Gregory RI. 2012. Lin28-mediated control of let-7 microRNA expression by alternative TUTases Zcchc11 (TUT4) and Zcchc6 (TUT7). RNA 18: 1875–1885.
-
(2012)
RNA
, vol.18
, pp. 1875-1885
-
-
Thornton, J.E.1
Chang, H.M.2
Piskounova, E.3
Gregory, R.I.4
-
138
-
-
84881086323
-
Cancer as a dysregulated epigenome allowing cellular growth advantage at the expense of the host
-
Timp W, Feinberg AP. 2013. Cancer as a dysregulated epigenome allowing cellular growth advantage at the expense of the host. Nat Rev Cancer 13: 497–510.
-
(2013)
Nat Rev Cancer
, vol.13
, pp. 497-510
-
-
Timp, W.1
Feinberg, A.P.2
-
139
-
-
84902289852
-
Recurrent somatic mutation in DROSHA induces microRNA profile changes in Wilms tumour
-
Torrezan GT, Ferreira EN, Nakahata AM, Barros BD, Castro MT, Correa BR, Krepischi AC, Olivieri EH, Cunha IW, Tabori U, et al. 2014. Recurrent somatic mutation in DROSHA induces microRNA profile changes in Wilms tumour. Nat Commun 5: 4039.
-
(2014)
Nat Commun
, vol.5
, pp. 4039
-
-
Torrezan, G.T.1
Ferreira, E.N.2
Nakahata, A.M.3
Barros, B.D.4
Castro, M.T.5
Correa, B.R.6
Krepischi, A.C.7
Olivieri, E.H.8
Cunha, I.W.9
Tabori, U.10
-
140
-
-
0038209414
-
Upregulation of c-MYC in WT1-mutant tumors: Assessment of WT1 putative transcriptional targets using cDNA microarray expression profiling of genetically defined Wilms’ tumors
-
Udtha M, Lee SJ, Alam R, Coombes K, Huff V. 2003. Upregulation of c-MYC in WT1-mutant tumors: assessment of WT1 putative transcriptional targets using cDNA microarray expression profiling of genetically defined Wilms’ tumors. Oncogene 22: 3821–3826.
-
(2003)
Oncogene
, vol.22
, pp. 3821-3826
-
-
Udtha, M.1
Lee, S.J.2
Alam, R.3
Coombes, K.4
Huff, V.5
-
141
-
-
84899740983
-
Lin28 sustains early renal progenitors and induces Wilms tumor
-
Urbach A, Yermalovich A, Zhang J, Spina CS, Zhu H, Perez- Atayde AR, Shukrun R, Charlton J, Sebire N, Mifsud W, et al. 2014. Lin28 sustains early renal progenitors and induces Wilms tumor. Genes Dev 28: 971–982.
-
(2014)
Genes Dev
, vol.28
, pp. 971-982
-
-
Urbach, A.1
Yermalovich, A.2
Zhang, J.3
Spina, C.S.4
Zhu, H.5
Perez-Atayde, A.R.6
Shukrun, R.7
Charlton, J.8
Sebire, N.9
Mifsud, W.10
-
142
-
-
0017744273
-
Prenatal multicarcinogenesis by ethylnitrosourea in mice
-
Vesselinovitch SD, Koka M, Rao KV, Mihailovich N, Rice JM. 1977. Prenatal multicarcinogenesis by ethylnitrosourea in mice. Cancer Res 37: 1822–1828.
-
(1977)
Cancer Res
, vol.37
, pp. 1822-1828
-
-
Vesselinovitch, S.D.1
Koka, M.2
Rao, K.V.3
Mihailovich, N.4
Rice, J.M.5
-
143
-
-
78751676408
-
Cells of origin in cancer
-
Visvader JE. 2011. Cells of origin in cancer. Nature 469: 314–322.
-
(2011)
Nature
, vol.469
, pp. 314-322
-
-
Visvader, J.E.1
-
144
-
-
18644383745
-
Frequent RASSF1A tumour suppressor gene promoter methylation in Wilms’ tumour and colorectal cancer
-
Wagner KJ, Cooper WN, Grundy RG, Caldwell G, Jones C, Wadey RB, Morton D, Schofield PN, Reik W, Latif F, et al. 2002. Frequent RASSF1A tumour suppressor gene promoter methylation in Wilms’ tumour and colorectal cancer. Oncogene 21: 7277–7282.
-
(2002)
Oncogene
, vol.21
, pp. 7277-7282
-
-
Wagner, K.J.1
Cooper, W.N.2
Grundy, R.G.3
Caldwell, G.4
Jones, C.5
Wadey, R.B.6
Morton, D.7
Schofield, P.N.8
Reik, W.9
Latif, F.10
-
145
-
-
84922778081
-
Recurrent DGCR8, DROSHA, and SIX homeodomainmutations in favorable histology Wilms tumors
-
Walz AL, Ooms A, Gadd S, Gerhard DS, Smith MA, Guidry Auvil JM, Meerzaman D, Chen Q-R, Hsu CH, Yan C, et al. 2015. Recurrent DGCR8, DROSHA, and SIX homeodomainmutations in favorable histology Wilms tumors. Cancer Cell 27: 286–297.
-
(2015)
Cancer Cell
, vol.27
, pp. 286-297
-
-
Walz, A.L.1
Ooms, A.2
Gadd, S.3
Gerhard, D.S.4
Smith, M.A.5
Guidry Auvil, J.M.6
Meerzaman, D.7
Chen, Q.-R.8
Hsu, C.H.9
Yan, C.10
-
146
-
-
84872128352
-
O’Sullivan M. 2013. miRNA profiles as a predictor of chemoresponsiveness in Wilms’ tumor blastema
-
Watson JA, Bryan K, Williams R, Popov S, Vujanic G, Coulomb A, Boccon-Gibod L, Graf N, Pritchard-Jones K, O’Sullivan M. 2013. miRNA profiles as a predictor of chemoresponsiveness in Wilms’ tumor blastema. PLoS ONE 8: e53417.
-
Plos ONE
, vol.8
-
-
Watson, J.A.1
Bryan, K.2
Williams, R.3
Popov, S.4
Vujanic, G.5
Coulomb, A.6
Boccon-Gibod, L.7
Graf, N.8
Pritchard-Jones, K.9
-
147
-
-
70350236512
-
WTX inactivation is a frequent, but late event in Wilms tumors without apparent clinical impact
-
Wegert J, Wittmann S, Leuschner I, Geissinger E, Graf N, Gessler M. 2009. WTX inactivation is a frequent, but late event in Wilms tumors without apparent clinical impact. Genes Chromosomes Cancer 48: 1102–1111.
-
(2009)
Genes Chromosomes Cancer
, vol.48
, pp. 1102-1111
-
-
Wegert, J.1
Wittmann, S.2
Leuschner, I.3
Geissinger, E.4
Graf, N.5
Gessler, M.6
-
148
-
-
84922769850
-
Mutations in the SIX1/2 pathway and the DROSHA/DGCR8miRNA microprocessor complex underlie high-risk blastemal type Wilms tumors
-
Wegert J, Ishaque N, Vardapour R, Georg C, Gu Z, Bieg M, Ziegler B, Bausenwein S, Nourkami N, Ludwig N, et al. 2015. Mutations in the SIX1/2 pathway and the DROSHA/DGCR8miRNA microprocessor complex underlie high-risk blastemal type Wilms tumors. Cancer Cell 27: 298–311.
-
(2015)
Cancer Cell
, vol.27
, pp. 298-311
-
-
Wegert, J.1
Ishaque, N.2
Vardapour, R.3
Georg, C.4
Gu, Z.5
Bieg, M.6
Ziegler, B.7
Bausenwein, S.8
Nourkami, N.9
Ludwig, N.10
-
149
-
-
0023831210
-
Genomic imprinting and carcinogenesis
-
Wilkins RJ. 1988. Genomic imprinting and carcinogenesis. Lancet 1: 329–331.
-
(1988)
Lancet
, vol.1
, pp. 329-331
-
-
Wilkins, R.J.1
-
150
-
-
77950641105
-
Subtype-specific FBXW7 mutation and MYCN copy number gain in Wilms’ tumor
-
Williams RD, Al-Saadi R, Chagtai T, Popov S, Messahel B, Sebire N, Gessler M, Wegert J, Graf N, Leuschner I, et al. 2010. Subtype-specific FBXW7 mutation and MYCN copy number gain in Wilms’ tumor. Clin Cancer Res 16: 2036–2045.
-
(2010)
Clin Cancer Res
, vol.16
, pp. 2036-2045
-
-
Williams, R.D.1
Al-Saadi, R.2
Chagtai, T.3
Popov, S.4
Messahel, B.5
Sebire, N.6
Gessler, M.7
Wegert, J.8
Graf, N.9
Leuschner, I.10
-
151
-
-
84924682507
-
Multiple mechanisms of MYCN dysregulation in Wilms tumour
-
(in press)
-
Williams RD, Chagtai T, Alcaide-German M, Apps J, Wegert J, Popov S, Vujanic G, Van Tinteren H, van den Heuvel-Eibrink MM, Kool M, et al. 2015. Multiple mechanisms of MYCN dysregulation in Wilms tumour. Oncotarget (in press).
-
(2015)
Oncotarget
-
-
Williams, R.D.1
Chagtai, T.2
Alcaide-German, M.3
Apps, J.4
Wegert, J.5
Popov, S.6
Vujanic, G.7
Van Tinteren, H.8
Van Den Heuvel-Eibrink, M.M.9
Kool, M.10
-
152
-
-
0037344296
-
Overexpression of human Dickkopf-1, an antagonist of wingless/WNT signaling, in human hepatoblastomas and Wilms’ tumors
-
Wirths O, Waha A, Weggen S, Schirmacher P, Kuhne T, Goodyer CG, Albrecht S, Von Schweinitz D, Pietsch T. 2003. Overexpression of human Dickkopf-1, an antagonist of wingless/WNT signaling, in human hepatoblastomas and Wilms’ tumors. Lab Invest 83: 429–434.
-
(2003)
Lab Invest
, vol.83
, pp. 429-434
-
-
Wirths, O.1
Waha, A.2
Weggen, S.3
Schirmacher, P.4
Kuhne, T.5
Goodyer, C.G.6
Albrecht, S.7
Von Schweinitz, D.8
Pietsch, T.9
-
153
-
-
84877731972
-
Biallelic DICER1 mutations occur in Wilms tumours
-
Wu MK, Sabbaghian N, Xu B, Addidou-Kalucki S, Bernard C, Zou D, Reeve AE, Eccles MR, Cole C, Choong CS, et al. 2013. Biallelic DICER1 mutations occur in Wilms tumours. J Pathol 230: 154–164.
-
(2013)
J Pathol
, vol.230
, pp. 154-164
-
-
Wu, M.K.1
Sabbaghian, N.2
Xu, B.3
Addidou-Kalucki, S.4
Bernard, C.5
Zou, D.6
Reeve, A.E.7
Eccles, M.R.8
Cole, C.9
Choong, C.S.10
-
154
-
-
0033672104
-
A novel imprinted gene, KCNQ1DN, within the WT2 critical region of human chromosome 11p15.5 and its reduced expression in Wilms’ tumors
-
Xin Z, Soejima H, Higashimoto K, Yatsuki H, Zhu X, Satoh Y, Masaki Z, Kaneko Y, Jinno Y, Fukuzawa R, et al. 2000. A novel imprinted gene, KCNQ1DN, within the WT2 critical region of human chromosome 11p15.5 and its reduced expression in Wilms’ tumors. J Biochem 128: 847–853.
-
(2000)
J Biochem
, vol.128
, pp. 847-853
-
-
Xin, Z.1
Soejima, H.2
Higashimoto, K.3
Yatsuki, H.4
Zhu, X.5
Satoh, Y.6
Masaki, Z.7
Kaneko, Y.8
Jinno, Y.9
Fukuzawa, R.10
-
155
-
-
84880573784
-
The EYA–SO/SIX complex in development and disease
-
Xu PX. 2013. The EYA–SO/SIX complex in development and disease. Pediatr Nephrol 28: 843–854.
-
(2013)
Pediatr Nephrol
, vol.28
, pp. 843-854
-
-
Xu, P.X.1
-
156
-
-
0041853845
-
Six1 is required for the early organogenesis of mammalian kidney
-
Xu PX, Zheng WM, Huang L, Maire P, Laclef C, Silvius D. 2003. Six1 is required for the early organogenesis of mammalian kidney. Development 130: 3085–3094.
-
(2003)
Development
, vol.130
, pp. 3085-3094
-
-
Xu, P.X.1
Zheng, W.M.2
Huang, L.3
Maire, P.4
Laclef, C.5
Silvius, D.6
-
157
-
-
79954600463
-
Tumor suppressor menin represses paired box gene 2 expression via Wilms tumor suppressor protein-polycomb group complex
-
Xu B, Zeng D-q, Wu Y, Zheng R, Gu L, Lin X, Hua X, Jin G-H. 2011. Tumor suppressor menin represses paired box gene 2 expression via Wilms tumor suppressor protein-polycomb group complex. J Biol Chem 286: 13937–13944.
-
(2011)
J Biol Chem
, vol.286
, pp. 13937-13944
-
-
Xu, B.1
D-Q, Z.2
Wu, Y.3
Zheng, R.4
Gu, L.5
Lin, X.6
Hua, X.7
Jin, G.-H.8
-
158
-
-
84921318905
-
Eya1 interacts with Six2 and Myc to regulate expansion of the nephron progenitor pool during nephrogenesis
-
Xu J, Wong EM, Cheng C, Li J, Sharkar MTK, Xu CY, Chen B, Sun J, Jing D, Xu PX. 2014. Eya1 interacts with Six2 and Myc to regulate expansion of the nephron progenitor pool during nephrogenesis. Dev Cell 31: 434–447.
-
(2014)
Dev Cell
, vol.31
, pp. 434-447
-
-
Xu, J.1
Wong, E.M.2
Cheng, C.3
Li, J.4
Sharkar, M.5
Xu, C.Y.6
Chen, B.7
Sun, J.8
Jing, D.9
Xu, P.X.10
-
159
-
-
84896861273
-
Effective gene targeting in rabbits using RNA-guided Cas9 nucleases
-
Yang D, Xu J, Zhu T, Fan J, Lai L, Zhang J, Chen YE. 2014. Effective gene targeting in rabbits using RNA-guided Cas9 nucleases. J Mol Cell Biol 6: 97–99.
-
(2014)
J Mol Cell Biol
, vol.6
, pp. 97-99
-
-
Yang, D.1
Xu, J.2
Zhu, T.3
Fan, J.4
Lai, L.5
Zhang, J.6
Chen, Y.E.7
-
160
-
-
0032781651
-
Proto-oncogene N-myc promoter is down regulated by the Wilms’ tumor suppressor gene WT1
-
Zhang X, Xing G, Saunders GF. 1999. Proto-oncogene N-myc promoter is down regulated by the Wilms’ tumor suppressor gene WT1. Anticancer Res 19: 1641–1648.
-
(1999)
Anticancer Res
, vol.19
, pp. 1641-1648
-
-
Zhang, X.1
Xing, G.2
Saunders, G.F.3
-
161
-
-
84907967475
-
Frequent hypermethylation of a CTCF binding site influences Wilms tumor 1 expression in Wilms tumors
-
Zitzmann F, Mayr D, Berger M, Stehr M, von Schweinitz D, Kappler R, Hubertus J. 2014. Frequent hypermethylation of a CTCF binding site influences Wilms tumor 1 expression in Wilms tumors. Oncol Rep 31: 1871–1876.
-
(2014)
Oncol Rep
, vol.31
, pp. 1871-1876
-
-
Zitzmann, F.1
Mayr, D.2
Berger, M.3
Stehr, M.4
Von Schweinitz, D.5
Kappler, R.6
Hubertus, J.7
|