-
1
-
-
58249088751
-
MicroRNAs: Target recognition and regulatory functions
-
Bartel, D.P. MicroRNAs: target recognition and regulatory functions. Cell 136, 215-233 (2009).
-
(2009)
Cell
, vol.136
, pp. 215-233
-
-
Bartel, D.P.1
-
2
-
-
77955644289
-
Mammalian microRNAs predominantly act to decrease target mRNA levels
-
Guo, H., Ingolia, N.T., Weissman, J.S. & Bartel, D.P. Mammalian microRNAs predominantly act to decrease target mRNA levels. Nature 466, 835-840 (2010).
-
(2010)
Nature
, vol.466
, pp. 835-840
-
-
Guo, H.1
Ingolia, N.T.2
Weissman, J.S.3
Bartel, D.P.4
-
3
-
-
56749091922
-
Embryonic stem cell-specific microRNAs regulate the G1-S transition and promote rapid proliferation
-
Wang, Y. et al. Embryonic stem cell-specific microRNAs regulate the G1-S transition and promote rapid proliferation. Nat. Genet. 40, 1478-1483 (2008).
-
(2008)
Nat. Genet.
, vol.40
, pp. 1478-1483
-
-
Wang, Y.1
-
4
-
-
76249119007
-
Opposing microRNA families regulate self-renewal in mouse embryonic stem cells
-
Melton, C., Judson, R.L. & Blelloch, R. Opposing microRNA families regulate self-renewal in mouse embryonic stem cells. Nature 463, 621-626 (2010).
-
(2010)
Nature
, vol.463
, pp. 621-626
-
-
Melton, C.1
Judson, R.L.2
Blelloch, R.3
-
5
-
-
34247589595
-
Control of stress-dependent cardiac growth and gene expression by a microRNA
-
DOI 10.1126/science.1139089
-
van Rooij, E. et al. Control of stress-dependent cardiac growth and gene expression by a microRNA. Science 316, 575-579 (2007). (Pubitemid 46683138)
-
(2007)
Science
, vol.316
, Issue.5824
, pp. 575-579
-
-
Van Rooij, E.1
Sutherland, L.B.2
Qi, X.3
Richardson, J.A.4
Hill, J.5
Olson, E.N.6
-
6
-
-
34147153781
-
Dysregulation of cardiogenesis, cardiac conduction, and cell cycle in mice lacking miRNA-1-2
-
DOI 10.1016/j.cell.2007.03.030, PII S0092867407003984
-
Zhao, Y. et al. Dysregulation of cardiogenesis, cardiac conduction, and cell cycle in mice lacking miRNA-1-2. Cell 129, 303-317 (2007). (Pubitemid 46574975)
-
(2007)
Cell
, vol.129
, Issue.2
, pp. 303-317
-
-
Zhao, Y.1
Ransom, J.F.2
Li, A.3
Vedantham, V.4
Von Drehle, M.5
Muth, A.N.6
Tsuchihashi, T.7
McManus, M.T.8
Schwartz, R.J.9
Srivastava, D.10
-
7
-
-
77952671841
-
MiRNAs in neuronal development, function and dysfunction
-
Saba, R. & Schratt, G.M. MiRNAs in neuronal development, function and dysfunction. Brain Res. 1338, 3-13 (2010).
-
(2010)
Brain Res.
, vol.1338
, pp. 3-13
-
-
Saba, R.1
Schratt, G.M.2
-
8
-
-
75649139134
-
Physiological and pathological roles for microRNAs in the immune system
-
O'Connell, R.M., Rao, D.S., Chaudhuri, A.A. & Baltimore, D. Physiological and pathological roles for microRNAs in the immune system. Nat. Rev. Immunol. 10, 111-122 (2010).
-
(2010)
Nat. Rev. Immunol.
, vol.10
, pp. 111-122
-
-
O'connell, R.M.1
Rao, D.S.2
Chaudhuri, A.A.3
Baltimore, D.4
-
9
-
-
33750370444
-
MicroRNA signatures in human cancers
-
DOI 10.1038/nrc1997, PII NRC1997
-
Calin, G.A. & Croce, C.M. MicroRNA signatures in human cancers. Nat. Rev. Cancer 6, 857-866 (2006). (Pubitemid 44629897)
-
(2006)
Nature Reviews Cancer
, vol.6
, Issue.11
, pp. 857-866
-
-
Calin, G.A.1
Croce, C.M.2
-
10
-
-
37749036293
-
Most Caenorhabditis elegans microRNAs are individually not essential for development or viability
-
Miska, E.A. et al. Most Caenorhabditis elegans microRNAs are individually not essential for development or viability. PLoS Genet. 3, e215 (2007).
-
(2007)
PLoS Genet.
, vol.3
-
-
Miska, E.A.1
-
11
-
-
4444262688
-
The knockout mouse project
-
DOI 10.1038/ng0904-921
-
Austin, C.P. et al. The knockout mouse project. Nat. Genet. 36, 921-924 (2004). (Pubitemid 351319639)
-
(2004)
Nature Genetics
, vol.36
, Issue.9
, pp. 921-924
-
-
Austin, C.P.1
Battey, J.F.2
Bradley, A.3
Bucan, M.4
Capecchi, M.5
Collins, F.S.6
Dove, W.F.7
Duyk, G.8
Dymecki, S.9
Eppig, J.T.10
Grieder, F.B.11
Heintz, N.12
Hicks, G.13
Insel, T.R.14
Joyner, A.15
Koller, B.H.16
Lloyd, K.C.K.17
Magnuson, T.18
Moore, M.W.19
Nagy, A.20
Pollock, J.D.21
Roses, A.D.22
Sands, A.T.23
Seed, B.24
Skarnes, W.C.25
Snoddy, J.26
Soriano, P.27
Stewart, D.J.28
Stewart, F.29
Stillman, B.30
Varmus, H.31
Varticovski, L.32
Verma, I.M.33
Vogt, T.F.34
Von Melchner, H.35
Witkowski, J.36
Woychik, R.P.37
Wurst, W.38
Yancopoulos, G.D.39
Young, S.G.40
Zambrowicz, B.41
more..
-
12
-
-
79959210305
-
A conditional knockout resource for the genome-wide study of mouse gene function
-
Skarnes, W.C. et al. A conditional knockout resource for the genome-wide study of mouse gene function. Nature 474, 337-342 (2011).
-
(2011)
Nature
, vol.474
, pp. 337-342
-
-
Skarnes, W.C.1
-
13
-
-
78651284860
-
The IKMC web portal: A central point of entry to data and resources from the International Knockout Mouse Consortium
-
Ringwald, M. et al. The IKMC web portal: a central point of entry to data and resources from the International Knockout Mouse Consortium. Nucleic Acids Res. 39, D849-D855 (2011).
-
(2011)
Nucleic Acids Res.
, vol.39
-
-
Ringwald, M.1
-
14
-
-
13844294261
-
Dicer-deficient mouse embryonic stem cells are defective in differentiation and centromeric silencing
-
DOI 10.1101/gad.1248505
-
Kanellopoulou, C. et al. Dicer-deficient mouse embryonic stem cells are defective in differentiation and centromeric silencing. Genes Dev. 19, 489-501 (2005). (Pubitemid 40256280)
-
(2005)
Genes and Development
, vol.19
, Issue.4
, pp. 489-501
-
-
Kanellopoulou, C.1
Muljo, S.A.2
Kung, A.L.3
Ganesan, S.4
Drapkin, R.5
Jenuwein, T.6
Livingston, D.M.7
Rajewsky, K.8
-
15
-
-
23344439006
-
The RNaseIII enzyme Dicer is required for morphogenesis but not patterning of the vertebrate limb
-
DOI 10.1073/pnas.0504834102
-
Harfe, B.D., McManus, M.T., Mansfield, J.H., Hornstein, E. & Tabin, C.J. The RNase III enzyme Dicer is required for morphogenesis but not patterning of the vertebrate limb. Proc. Natl. Acad. Sci. USA 102, 10898-10903 (2005). (Pubitemid 41105964)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.31
, pp. 10898-10903
-
-
Harfe, B.D.1
McManus, M.T.2
Mansfield, J.H.3
Hornstein, E.4
Tabin, C.J.5
-
16
-
-
20844432885
-
T cell lineage choice and differentiation in the absence of the RNase III enzyme Dicer
-
DOI 10.1084/jem.20050572
-
Cobb, B.S. et al. T cell lineage choice and differentiation in the absence of the RNase III enzyme Dicer. J. Exp. Med. 201, 1367-1373 (2005). (Pubitemid 40664081)
-
(2005)
Journal of Experimental Medicine
, vol.201
, Issue.9
, pp. 1367-1373
-
-
Cobb, B.S.1
Nesterova, T.B.2
Thompson, E.3
Hertweck, A.4
O'Connor, E.5
Godwin, J.6
Wilson, C.B.7
Brockdorff, N.8
Fisher, A.G.9
Smale, S.T.10
Merkenschlager, M.11
-
17
-
-
34247584465
-
Requirement of bic/microRNA-155 for normal immune function
-
DOI 10.1126/science.1139253
-
Rodriguez, A. et al. Requirement of bic/microRNA-155 for normal immune function. Science 316, 608-611 (2007). (Pubitemid 46683148)
-
(2007)
Science
, vol.316
, Issue.5824
, pp. 608-611
-
-
Rodriguez, A.1
Vigorito, E.2
Clare, S.3
Warren, M.V.4
Couttet, P.5
Soond, D.R.6
Van Dongen, S.7
Grocock, R.J.8
Das, P.P.9
Miska, E.A.10
Vetrie, D.11
Okkenhaug, K.12
Enright, A.J.13
Dougan, G.14
Turner, M.15
Bradley, A.16
-
18
-
-
34247594818
-
Regulation of the germinal center response by microRNA-155
-
Thai, T.H. et al. Regulation of the germinal center response by microRNA-155. Science 316, 604-608 (2007).
-
(2007)
Science
, vol.316
, pp. 604-608
-
-
Thai, T.H.1
-
19
-
-
77956632634
-
Function of miR-146a in controlling Treg cell-mediated regulation of Th1 responses
-
Lu, L.F. et al. Function of miR-146a in controlling Treg cell-mediated regulation of Th1 responses. Cell 142, 914-929 (2010).
-
(2010)
Cell
, vol.142
, pp. 914-929
-
-
Lu, L.F.1
-
20
-
-
33644750115
-
MiRBase: MicroRNA sequences, targets and gene nomenclature
-
Griffiths-Jones, S., Grocock, R.J., van Dongen, S., Bateman, A. & Enright, A.J. miRBase: microRNA sequences, targets and gene nomenclature. Nucleic Acids Res. 34, D140-D144 (2006).
-
(2006)
Nucleic Acids Res.
, vol.34
-
-
Griffiths-Jones, S.1
Grocock, R.J.2
Van Dongen, S.3
Bateman, A.4
Enright, A.J.5
-
21
-
-
9344235449
-
Human microRNAs are processed from capped, polyadenylated transcripts that can also function as mRNAs
-
DOI 10.1261/rna.7135204
-
Cai, X., Hagedorn, C.H. & Cullen, B.R. Human microRNAs are processed from capped, polyadenylated transcripts that can also function as mRNAs. RNA 10, 1957-1966 (2004). (Pubitemid 39557833)
-
(2004)
RNA
, vol.10
, Issue.12
, pp. 1957-1966
-
-
Cai, X.1
Hagedorn, C.H.2
Cullen, B.R.3
-
22
-
-
48449084118
-
Connecting microRNA genes to the core transcriptional regulatory circuitry of embryonic stem cells
-
Marson, A. et al. Connecting microRNA genes to the core transcriptional regulatory circuitry of embryonic stem cells. Cell 134, 521-533 (2008).
-
(2008)
Cell
, vol.134
, pp. 521-533
-
-
Marson, A.1
-
23
-
-
8144225486
-
MicroRNA genes are transcribed by RNA polymerase II
-
DOI 10.1038/sj.emboj.7600385
-
Lee, Y. et al. MicroRNA genes are transcribed by RNA polymerase II. EMBO J. 23, 4051-4060 (2004). (Pubitemid 39472426)
-
(2004)
EMBO Journal
, vol.23
, Issue.20
, pp. 4051-4060
-
-
Lee, Y.1
Kim, M.2
Han, J.3
Yeom, K.-H.4
Lee, S.5
Baek, S.H.6
Kim, V.N.7
-
24
-
-
6344281172
-
Identification of mammalian microRNA host genes and transcription units
-
DOI 10.1101/gr.2722704
-
Rodriguez, A., Griffiths-Jones, S., Ashurst, J.L. & Bradley, A. Identification of mammalian microRNA host genes and transcription units. Genome Res. 14, 1902-1910 (2004). (Pubitemid 39386503)
-
(2004)
Genome Research
, vol.14
, Issue.10 A
, pp. 1902-1910
-
-
Rodriguez, A.1
Griffiths-Jones, S.2
Ashurst, J.L.3
Bradley, A.4
-
25
-
-
34250315750
-
A recombineering based approach for high-throughput conditional knockout targeting vector construction
-
Chan, W. et al. A recombineering based approach for high-throughput conditional knockout targeting vector construction. Nucleic Acids Res. 35, e64 (2007).
-
(2007)
Nucleic Acids Res.
, vol.35
-
-
Chan, W.1
-
26
-
-
0033762448
-
A new positive/negative selectable marker, puDeltatk, for use in embryonic stem cells
-
Chen, Y.T. & Bradley, A. A new positive/negative selectable marker, puDeltatk, for use in embryonic stem cells. Genesis 28, 31-35 (2000).
-
(2000)
Genesis
, vol.28
, pp. 31-35
-
-
Chen, Y.T.1
Bradley, A.2
-
27
-
-
0028109636
-
Use of mutated FLP recognition target (FRT) sites for the exchange of expression cassettes at defined chromosomal loci
-
DOI 10.1021/bi00209a003
-
Schlake, T. & Bode, J. Use of mutated FLP recognition target (FRT) sites for the exchange of expression cassettes at defined chromosomal loci. Biochemistry 33, 12746-12751 (1994). (Pubitemid 24352862)
-
(1994)
Biochemistry
, vol.33
, Issue.43
, pp. 12746-12751
-
-
Schlake, T.1
Bode, J.2
-
28
-
-
67649574240
-
Agouti C57BL/6N embryonic stem cells for mouse genetic resources
-
Pettitt, S.J. et al. Agouti C57BL/6N embryonic stem cells for mouse genetic resources. Nat. Methods 6, 493-495 (2009).
-
(2009)
Nat. Methods
, vol.6
, pp. 493-495
-
-
Pettitt, S.J.1
-
29
-
-
33947647023
-
High-efficiency FLP and PhiC31 site-specific recombination in mammalian cells
-
Raymond, C.S. & Soriano, P. High-efficiency FLP and PhiC31 site-specific recombination in mammalian cells. PLoS ONE 2, e162 (2007).
-
(2007)
PLoS ONE
, vol.2
-
-
Raymond, C.S.1
Soriano, P.2
-
30
-
-
11344273450
-
DNA recombination with a heterospecific Cre homolog identified from comparison of the pac-c1 regions of P1-related phages
-
DOI 10.1093/nar/gkh941
-
Sauer, B. & McDermott, J. DNA recombination with a heterospecific Cre homolog identified from comparison of the pac-c1 regions of P1-related phages. Nucleic Acids Res. 32, 6086-6095 (2004). (Pubitemid 40074003)
-
(2004)
Nucleic Acids Research
, vol.32
, Issue.20
, pp. 6086-6095
-
-
Sauer, B.1
McDermott, J.2
-
31
-
-
70450200653
-
Dre recombinase, like Cre, is a highly efficient site-specific recombinase in E. coli, mammalian cells and mice
-
Anastassiadis, K. et al. Dre recombinase, like Cre, is a highly efficient site-specific recombinase in E. coli, mammalian cells and mice. Dis. Model. Mech. 2, 508-515 (2009).
-
(2009)
Dis. Model. Mech.
, vol.2
, pp. 508-515
-
-
Anastassiadis, K.1
-
32
-
-
0042442335
-
Embryonic stem cell-specific microRNAs
-
DOI 10.1016/S1534-5807(03)00227-2, PII S1534580703002272
-
Houbaviy, H.B., Murray, M.F. & Sharp, P.A. Embryonic stem cell-specific MicroRNAs. Dev. Cell 5, 351-358 (2003). (Pubitemid 37006477)
-
(2003)
Developmental Cell
, vol.5
, Issue.2
, pp. 351-358
-
-
Houbaviy, H.B.1
Murray, M.F.2
Sharp, P.A.3
-
33
-
-
77952368550
-
Mammalian microRNAs: Experimental evaluation of novel and previously annotated genes
-
Chiang, H.R. et al. Mammalian microRNAs: experimental evaluation of novel and previously annotated genes. Genes Dev. 24, 992-1009 (2010).
-
(2010)
Genes Dev.
, vol.24
, pp. 992-1009
-
-
Chiang, H.R.1
-
35
-
-
0037352031
-
A highly efficient recombineering-based method for generating conditional knockout mutations
-
DOI 10.1101/gr.749203
-
Liu, P., Jenkins, N.A. & Copeland, N.G. A highly efficient recombineering-based method for generating conditional knockout mutations. Genome Res. 13, 476-484 (2003). (Pubitemid 36395405)
-
(2003)
Genome Research
, vol.13
, Issue.3
, pp. 476-484
-
-
Liu, P.1
Jenkins, N.A.2
Copeland, N.G.3
-
36
-
-
0025188130
-
The Wnt-1 (int-1) proto-oncogene is required for development of a large region of the mouse brain
-
McMahon, A.P. & Bradley, A. The Wnt-1 (int-1) proto-oncogene is required for development of a large region of the mouse brain. Cell 62, 1073-1085 (1990).
-
(1990)
Cell
, vol.62
, pp. 1073-1085
-
-
McMahon, A.P.1
Bradley, A.2
-
37
-
-
0036134448
-
Embryonic stem cells as a model to study cardiac, skeletal muscle, and vascular smooth muscle cell differentiation
-
Wobus, A.M., Guan, K., Yang, H.T. & Boheler, K.R. Embryonic stem cells as a model to study cardiac, skeletal muscle, and vascular smooth muscle cell differentiation. Methods Mol. Biol. 185, 127-156 (2002).
-
(2002)
Methods Mol. Biol.
, vol.185
, pp. 127-156
-
-
Wobus, A.M.1
Guan, K.2
Yang, H.T.3
Boheler, K.R.4
-
38
-
-
0024509412
-
Cre-stimulated recombination at loxP-containing DNA sequences placed into the mammalian genome
-
Sauer, B. & Henderson, N. Cre-stimulated recombination at loxP-containing DNA sequences placed into the mammalian genome. Nucleic Acids Res. 17, 147-161 (1989). (Pubitemid 19030024)
-
(1989)
Nucleic Acids Research
, vol.17
, Issue.1
, pp. 147-161
-
-
Sauer, B.1
Henderson, N.2
-
39
-
-
0028928854
-
Site-specific recombination of a transgene in fertilized eggs by transient expression of Cre recombinase
-
Araki, K., Araki, M., Miyazaki, J. & Vassalli, P. Site-specific recombination of a transgene in fertilized eggs by transient expression of Cre recombinase. Proc. Natl. Acad. Sci. USA 92, 160-164 (1995).
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 160-164
-
-
Araki, K.1
Araki, M.2
Miyazaki, J.3
Vassalli, P.4
-
40
-
-
0344333424
-
DNA cassette exchange in ES cells mediated by FLF recombinase: An efficient strategy for repeated modification of tagged loci by marker-free constructs
-
DOI 10.1021/bi980288t
-
Seibler, J., Schubeler, D., Fiering, S., Groudine, M. & Bode, J. DNA cassette exchange in ES cells mediated by Flp recombinase: an efficient strategy for repeated modification of tagged loci by marker-free constructs. Biochemistry 37, 6229-6234 (1998). (Pubitemid 28213639)
-
(1998)
Biochemistry
, vol.37
, Issue.18
, pp. 6229-6234
-
-
Seibler, J.1
Schubeler, D.2
Fiering, S.3
Groudine, M.4
Bode, J.5
-
41
-
-
0031874849
-
Improved properties of FLP recombinase evolved by cycling mutagenesis
-
DOI 10.1038/nbt0798-657
-
Buchholz, F., Angrand, P.O. & Stewart, A.F. Improved properties of FLP recombinase evolved by cycling mutagenesis. Nat. Biotechnol. 16, 657-662 (1998). (Pubitemid 28334324)
-
(1998)
Nature Biotechnology
, vol.16
, Issue.7
, pp. 657-662
-
-
Buchholz, F.1
Angrand, P.-O.2
Stewart, A.F.3
|