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Volumn 389, Issue 6653, 1997, Pages 809-815

Transactivation of Igf2 in a mouse model of Beckwith-Wiedemann syndrome

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EID: 0030735169     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/39797     Document Type: Article
Times cited : (280)

References (44)
  • 1
    • 0025320906 scopus 로고
    • A growth-deficiency phenotype in heterozygous mice carrying an insulin-like growth factor-II gene disrupted by targeting
    • De Chiara, T. M., Efstratiadis, A. & Robertson, E. J. A growth-deficiency phenotype in heterozygous mice carrying an insulin-like growth factor-II gene disrupted by targeting. Nature 345, 78-80 (1990).
    • (1990) Nature , vol.345 , pp. 78-80
    • De Chiara, T.M.1    Efstratiadis, A.2    Robertson, E.J.3
  • 2
    • 0025967857 scopus 로고
    • Parental imprinting of the mouse insulin-like growth factor-II gene
    • DeChiara, T. M., Robertson, E. J. & Efstratiadis, A. Parental imprinting of the mouse insulin-like growth factor-II gene. Cell 64, 849-859 (1991).
    • (1991) Cell , vol.64 , pp. 849-859
    • DeChiara, T.M.1    Robertson, E.J.2    Efstratiadis, A.3
  • 3
    • 0030856668 scopus 로고    scopus 로고
    • Imprinting in clusters: Lessons from Beckwith-Wiedemann syndrome
    • Reik, W. & Maher, E. R. Imprinting in clusters: lessons from Beckwith-Wiedemann syndrome. Trends Genet. 13, 330-334 (1997).
    • (1997) Trends Genet. , vol.13 , pp. 330-334
    • Reik, W.1    Maher, E.R.2
  • 6
    • 0030993133 scopus 로고    scopus 로고
    • Deletion of the H19 transcription unit reveals the existence of a putative imprinting control element
    • Ripoche, M. A., Kress, C., Pirier, F. & Dandolo, L. Deletion of the H19 transcription unit reveals the existence of a putative imprinting control element. Genes. Dev. 11, 1596-1604 (1997).
    • (1997) Genes. Dev. , vol.11 , pp. 1596-1604
    • Ripoche, M.A.1    Kress, C.2    Pirier, F.3    Dandolo, L.4
  • 7
    • 0026781474 scopus 로고
    • Parental imprinting-potentially active chromatin of the repressed maternal allele of the mouse insulin-like growth factor-II (IGF2) gene
    • Sasaki, H. et al. Parental imprinting-potentially active chromatin of the repressed maternal allele of the mouse insulin-like growth factor-II (IGF2) gene. Genes Dev. 6, 1843-1856 (1992).
    • (1992) Genes Dev. , vol.6 , pp. 1843-1856
    • Sasaki, H.1
  • 8
    • 0027937839 scopus 로고
    • Development control of allelic methylation in the imprinted mouse IGF2 and H19 genes
    • Feil, R., Walter, J., Allen, N. D. & Reik, W. Development control of allelic methylation in the imprinted mouse IGF2 and H19 genes. Development 120, 2933-2943 (1994).
    • (1994) Development , vol.120 , pp. 2933-2943
    • Feil, R.1    Walter, J.2    Allen, N.D.3    Reik, W.4
  • 9
    • 0001443162 scopus 로고    scopus 로고
    • eds Russo, V. E. A., Martienssen, R. A. & Riggs, A. D. (Cold Spring Harbor Laboratory Press, NY)
    • Walter, J. et al. in Epigenetic Mechanisms of Gene Regulation (eds Russo, V. E. A., Martienssen, R. A. & Riggs, A. D.) 195-213 (Cold Spring Harbor Laboratory Press, NY, 1996).
    • (1996) Epigenetic Mechanisms of Gene Regulation , pp. 195-213
    • Walter, J.1
  • 10
    • 0031061679 scopus 로고    scopus 로고
    • Genomic regions regulating imprinting and insulin-like growth factor-II promoter 3 activity in transgenics: Novel enhancer and silencer elements
    • Ward, A. et al. Genomic regions regulating imprinting and insulin-like growth factor-II promoter 3 activity in transgenics: novel enhancer and silencer elements. Genes Funct. 1, 25-36 (1997).
    • (1997) Genes Funct. , vol.1 , pp. 25-36
    • Ward, A.1
  • 11
    • 0027287437 scopus 로고
    • Genomic imprinting and gene activation in cancer
    • Feinberg, A. P. Genomic imprinting and gene activation in cancer Nature Genet 4, 110-113 (1993).
    • (1993) Nature Genet , vol.4 , pp. 110-113
    • Feinberg, A.P.1
  • 12
    • 0028880017 scopus 로고
    • Mammary-cancer in transgenic mice expressing insulin-like growth-factor II (IGFII)
    • Bates, P. et al. Mammary-cancer in transgenic mice expressing insulin-like growth-factor II (IGFII). Brit. J. Cancer 72, 1189-1193 (1995).
    • (1995) Brit. J. Cancer , vol.72 , pp. 1189-1193
    • Bates, P.1
  • 13
    • 0028356419 scopus 로고
    • A second signal supplied by insulin-like growth factor II in oncogene-induced tumorigenesis
    • Christofori, G., Naik, P. & Hanahan, D. A. A second signal supplied by insulin-like growth factor II in oncogene-induced tumorigenesis. Nature 369, 414-418 (1994).
    • (1994) Nature , vol.369 , pp. 414-418
    • Christofori, G.1    Naik, P.2    Hanahan, D.A.3
  • 14
    • 0028318189 scopus 로고
    • Altered body composition and increased frequency of diverse malignancies in insulin-like growth factor II transgenic mice
    • Rogler, C. E. et al. Altered body composition and increased frequency of diverse malignancies in insulin-like growth factor II transgenic mice. J. Biol. Chem. 269, 13779-13784 (1994).
    • (1994) J. Biol. Chem. , vol.269 , pp. 13779-13784
    • Rogler, C.E.1
  • 15
    • 0028470672 scopus 로고
    • Beckwith-Wiedemann syndrome
    • Elliott, M. & Maher, E. R. Beckwith-Wiedemann syndrome. J. Med. Genet. 31, 560-564 (1994).
    • (1994) J. Med. Genet. , vol.31 , pp. 560-564
    • Elliott, M.1    Maher, E.R.2
  • 16
    • 0027420362 scopus 로고
    • Disruption of insulin-like growth factor-II imprinting in Beckwith-Weidemann syndrome
    • Weksberg, R., Shen, D. R., Fei, Y. L., Song, Q. L. & Squire, J. Disruption of insulin-like growth factor-II imprinting in Beckwith-Weidemann syndrome. Nature Genet. 5, 143-150 (1994).
    • (1994) Nature Genet. , vol.5 , pp. 143-150
    • Weksberg, R.1    Shen, D.R.2    Fei, Y.L.3    Song, Q.L.4    Squire, J.5
  • 17
    • 0030827119 scopus 로고    scopus 로고
    • Imprinting of Igf2 and H19: Lack of reciprocity in sporadic Beckwith-Wiedemann syndrome
    • Joyce, J. A. et al. Imprinting of Igf2 and H19: Lack of reciprocity in sporadic Beckwith-Wiedemann syndrome. Hum. Mol. Genet. 6, 1543-1548 (1997).
    • (1997) Hum. Mol. Genet. , vol.6 , pp. 1543-1548
    • Joyce, J.A.1
  • 18
    • 0028862472 scopus 로고
    • Imprinting mutations in the Beckwith-Wiedemann syndrome suggested by an altered imprinting pattern in the IGF2-H19 domain
    • Reik, W. et al. Imprinting mutations in the Beckwith-Wiedemann syndrome suggested by an altered imprinting pattern in the IGF2-H19 domain. Hum. Mol. Genet. 4, 2379-2385 (1995).
    • (1995) Hum. Mol. Genet. , vol.4 , pp. 2379-2385
    • Reik, W.1
  • 19
    • 0029806141 scopus 로고    scopus 로고
    • Imprinting mutation in the Beckwith-Wiedemann syndrome leads to biallelic IGF2 expression through an H19-independent pathway
    • Brown, K. W. et al. Imprinting mutation in the Beckwith-Wiedemann syndrome leads to biallelic IGF2 expression through an H19-independent pathway. Hum. Mol. Genet. 5, 2027-2032 (1996).
    • (1996) Hum. Mol. Genet. , vol.5 , pp. 2027-2032
    • Brown, K.W.1
  • 20
    • 0031046285 scopus 로고    scopus 로고
    • Human KvLQT1 gene shows tissue-specific imprinting and encompasses Beckwith-Wiedemann syndrome chromosomal rearrangements
    • Lee, M. P., Hu, R. J., Johnson, L. A. & Feinberg, A. P. Human KvLQT1 gene shows tissue-specific imprinting and encompasses Beckwith-Wiedemann syndrome chromosomal rearrangements. Nature Genet. 15, 181-185 (1997).
    • (1997) Nature Genet. , vol.15 , pp. 181-185
    • Lee, M.P.1    Hu, R.J.2    Johnson, L.A.3    Feinberg, A.P.4
  • 21
    • 16044364516 scopus 로고    scopus 로고
    • Kip2 is mutated in Beckwith-Wiedemann syndrome
    • Kip2 is mutated in Beckwith-Wiedemann syndrome. Nature Genet. 14, 171-173 (1996).
    • (1996) Nature Genet. , vol.14 , pp. 171-173
    • Hatada, I.1
  • 22
    • 1842335753 scopus 로고    scopus 로고
    • Kip2 indicates a role in Beckwith-Wiedemann syndrome
    • Kip2 indicates a role in Beckwith-Wiedemann syndrome. Nature 387, 151-158 (1997).
    • (1997) Nature , vol.387 , pp. 151-158
    • Zhang, P.1
  • 23
    • 0030955563 scopus 로고    scopus 로고
    • Kip2 results in increased apoptosis and delayed differentiation during mouse development
    • Kip2 results in increased apoptosis and delayed differentiation during mouse development. Genes Dev. 11, 973-983 (1997).
    • (1997) Genes Dev. , vol.11 , pp. 973-983
    • Yan, Y.1    Frisén, J.2    Lee, M.H.3    Massagué, J.4    Barbacid, M.5
  • 24
    • 0028575985 scopus 로고
    • Loss of the imprinted IGF2/cation-independent mannose 6-phosphate receptor results in fetal overgrowth and perinatal lethality
    • Lau, M. M. H. et al. Loss of the imprinted IGF2/cation-independent mannose 6-phosphate receptor results in fetal overgrowth and perinatal lethality. Genes Dev. 8, 2953-2963 (1994).
    • (1994) Genes Dev. , vol.8 , pp. 2953-2963
    • Lau, M.M.H.1
  • 25
    • 0027999284 scopus 로고
    • Regulation of embryonic growth and lysosomal targeting by the imprinted IGF2/MPR gene
    • Wang, Z. Q., Fun, M. R., Barlow, D. P. & Wagner, E. F. Regulation of embryonic growth and lysosomal targeting by the imprinted IGF2/MPR gene. Nature 372, 464-467 (1994).
    • (1994) Nature , vol.372 , pp. 464-467
    • Wang, Z.Q.1    Fun, M.R.2    Barlow, D.P.3    Wagner, E.F.4
  • 26
    • 0030221121 scopus 로고    scopus 로고
    • Mouse mutants lacking the type-2 IGF receptor (IGF2R) are rescued from perinatal lethality in IGF2 and IGF1R null backgrounds
    • Ludwig, T. et al. Mouse mutants lacking the type-2 IGF receptor (IGF2R) are rescued from perinatal lethality in IGF2 and IGF1R null backgrounds. Dev. Biol. 177, 517-535 (1996).
    • (1996) Dev. Biol. , vol.177 , pp. 517-535
    • Ludwig, T.1
  • 27
    • 0026428611 scopus 로고
    • Embryological and molecular investigations of parental imprinting on mouse chromosome 7
    • Ferguson-Smith, A. C., Cattanach, B. M., Barton, S. C., Beechey, C. V. & Surani, M. A. Embryological and molecular investigations of parental imprinting on mouse chromosome 7. Nature 351, 667-670 (1991).
    • (1991) Nature , vol.351 , pp. 667-670
    • Ferguson-Smith, A.C.1    Cattanach, B.M.2    Barton, S.C.3    Beechey, C.V.4    Surani, M.A.5
  • 29
    • 0028046891 scopus 로고
    • The cell-type specific IGF2 expression during early human development correlates to the pattern of overgrowth and neoplasia in the Beckwith-Wiedemann syndrome
    • Hedborg, F., Holmgren, L., Sandstedt, B. & Ohlsson, R. The cell-type specific IGF2 expression during early human development correlates to the pattern of overgrowth and neoplasia in the Beckwith-Wiedemann syndrome. Am. J. Pathol. 145, 802-817 (1994).
    • (1994) Am. J. Pathol. , vol.145 , pp. 802-817
    • Hedborg, F.1    Holmgren, L.2    Sandstedt, B.3    Ohlsson, R.4
  • 30
    • 0027231511 scopus 로고
    • Parental allele-specific methylation of the human insulin-like growth factor II gene and Beckwith-Wiedemann syndrome
    • Schneid, H. et al. Parental allele-specific methylation of the human insulin-like growth factor II gene and Beckwith-Wiedemann syndrome. J. Med. Genet. 30, 353-362 (1993).
    • (1993) J. Med. Genet. , vol.30 , pp. 353-362
    • Schneid, H.1
  • 31
    • 0027999665 scopus 로고
    • Mosaic uniparental disomy in Beckwith-Wiedemann syndrome
    • Slatter, R. E. et al. Mosaic uniparental disomy in Beckwith-Wiedemann syndrome. J. Med. Genet. 31, 749-753 (1994).
    • (1994) J. Med. Genet. , vol.31 , pp. 749-753
    • Slatter, R.E.1
  • 32
    • 0029939816 scopus 로고    scopus 로고
    • Somatic overgrowth associated with overexpression of insulin-like growth factor II
    • Morison, I. M., Becroft, D. M., Taniguchi, T., Woods, C. G. & Reeve, A. E. Somatic overgrowth associated with overexpression of insulin-like growth factor II. Nature Med. 2, 311-316 (1996).
    • (1996) Nature Med. , vol.2 , pp. 311-316
    • Morison, I.M.1    Becroft, D.M.2    Taniguchi, T.3    Woods, C.G.4    Reeve, A.E.5
  • 33
    • 13344261391 scopus 로고    scopus 로고
    • Mutations in GPC3, a glypican gene, cause the Simpson-Golabi-Behmel overgrowth syndrome
    • Pilia, G. et al. Mutations in GPC3, a glypican gene, cause the Simpson-Golabi-Behmel overgrowth syndrome. Nature Genet. 12, 241-247 (1996).
    • (1996) Nature Genet. , vol.12 , pp. 241-247
    • Pilia, G.1
  • 34
    • 0030032278 scopus 로고    scopus 로고
    • Mouse embryos with paternal duplication of an imprinted chromosome 7 region die at midgestation and lack placental spongiotrophoblast
    • McLaughlin, K. J., Szabo, P., Haegel, H. & Mann, J. R. Mouse embryos with paternal duplication of an imprinted chromosome 7 region die at midgestation and lack placental spongiotrophoblast. Development 122, 265-270 (1996).
    • (1996) Development , vol.122 , pp. 265-270
    • McLaughlin, K.J.1    Szabo, P.2    Haegel, H.3    Mann, J.R.4
  • 35
    • 0030015418 scopus 로고    scopus 로고
    • Dynamic methylation adjustment and counting as part of imprinting mechanisms
    • Shemer, R. et al. Dynamic methylation adjustment and counting as part of imprinting mechanisms. Proc. Natl Acad. Sci. USA 93, 6371-6376 (1996).
    • (1996) Proc. Natl Acad. Sci. USA , vol.93 , pp. 6371-6376
    • Shemer, R.1
  • 36
    • 0030903760 scopus 로고    scopus 로고
    • Aberrant methylation of an imprinted gene U2af1-rs1 caused by its own transgene
    • Hatada, I. et al. Aberrant methylation of an imprinted gene U2af1-rs1 caused by its own transgene. J. Biol. Chem. 272, 9120-9122 (1997).
    • (1997) J. Biol. Chem. , vol.272 , pp. 9120-9122
    • Hatada, I.1
  • 37
    • 0030895047 scopus 로고    scopus 로고
    • Long-range cis effects of ectopic X-inactivation centres on a mouse autosome
    • Lee, J. T. & Jaenisch, R. Long-range cis effects of ectopic X-inactivation centres on a mouse autosome. Nature 386, 272-275 (1997).
    • (1997) Nature , vol.386 , pp. 272-275
    • Lee, J.T.1    Jaenisch, R.2
  • 38
    • 0031001346 scopus 로고    scopus 로고
    • Xist has properties of the X-chromosome inactivation centre
    • Herzing, L. B. K., Romer, J. T., Horn, J. M. & Ashworth, A. Xist has properties of the X-chromosome inactivation centre. Nature 386, 272-275 (1997).
    • (1997) Nature , vol.386 , pp. 272-275
    • Herzing, L.B.K.1    Romer, J.T.2    Horn, J.M.3    Ashworth, A.4
  • 39
    • 0030608276 scopus 로고    scopus 로고
    • Nucleotide sequence of a 28 kb mouse genomic region comprising the imprinted Igf2 gene
    • Sasaki, H. et al. Nucleotide sequence of a 28 kb mouse genomic region comprising the imprinted Igf2 gene. DNA Res. 3, 331-335 (1996).
    • (1996) DNA Res. , vol.3 , pp. 331-335
    • Sasaki, H.1
  • 40
    • 0025600899 scopus 로고
    • Evolution of insulin-like growth factor II: Characterisation of the mouse Igf2 gene and identification of two pseudo-exons
    • Rotwein, P. & Hall, L. J. Evolution of insulin-like growth factor II: characterisation of the mouse Igf2 gene and identification of two pseudo-exons. DNA Cell Biol. 9, 725-735 (1990).
    • (1990) DNA Cell Biol. , vol.9 , pp. 725-735
    • Rotwein, P.1    Hall, L.J.2
  • 43
    • 0021770917 scopus 로고
    • Efficient in vitro synthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter
    • Melton, D. A. et al. Efficient in vitro synthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter. Nucleic Acids Res. 12, 7035-7056 (1984).
    • (1984) Nucleic Acids Res. , vol.12 , pp. 7035-7056
    • Melton, D.A.1


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