Correlation of germ-line mutations and two-hit inactivation of the WT1 gene with Wilms tumors of stromal-predominant histology

Proceedings of the National Academy of Sciences of the United States of America

Volumn 94, Issue 8, 1997, Pages 3972-3977

  Schumacher, V ^a,f   Schneider, S ^a   Figge, A ^a   Wildhardt, G ^b   Harms, D ^c   Schmidt, D ^d   Weirich, A ^e   Ludwig, R ^e   Royer Pokora, B ^a,f  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b JOHANNES GUTENBERG UNIVERSITY   (Germany)

^c UNIVERSITY HOSPITAL SCHLESWIG HOLSTEIN   (Germany)

^d Institute of Pathology   (Germany)

^e UNIVERSITY HOSPITAL HEIDELBERG   (Germany)

^f MAX PLANCK INSTITUTE FOR MOLECULAR GENETICS   (Germany)

Author keywords

histopathology; nephroblastoma; SSCP analysis; truncation mutations; tumor suppressor gene

Indexed keywords

ALTERNATIVE RNA SPLICING; AMINO TERMINAL SEQUENCE; ANTIGEN EXPRESSION; ARTICLE; CHROMOSOME 16Q; CYTOARCHITECTURE; GENE ACTIVATION; GENE LOCATION; GENE MUTATION; GENITAL TRACT INFECTION; GERM LINE; HISTOPATHOLOGY; HUMAN; HUMAN CELL; NEPHROBLASTOMA; NONSENSE MUTATION; PRIORITY JOURNAL; TRANSCRIPTION REGULATION; TUMOR SUPPRESSOR GENE;

DNA-BINDING PROTEINS; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, TUMOR SUPPRESSOR; GENES, WILMS TUMOR; GERM-LINE MUTATION; HUMANS; TRANSCRIPTION FACTORS; WILMS TUMOR; WT1 PROTEINS;

EID: 0030889197     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.94.8.3972     Document Type: Article

References (46)

1. Call, K. M., Glaser, T., Ito, C. Y., Buckler, A. J., Pelletier, J., Haber, D. A., Rose, E. A., Kral, A., Yeger, H., Lewis, W. H., Jones, C. & Housman, D. E. (1990) Cell 60, 509-520.
2. Gessler, M., Poustka, A., Cavenee, W., Neve, R. L., Orkin, S. H. & Bruns, G. A. P. (1990) Nature (London) 343, 774-778.
3. Grundy, P., Koufos, A., Morgan. K., Li, F. P., Meadows, A. T. & Cavenee, W. K. (1988) Nature (London) 336, 374-376.
4. Huff, V., Compton, D. A., Chao, L. Y., Strong, L. C., Geiser, C. F. & Saunders, G. F. (1988) Nature (London) 336, 377-378.
5. Huff, V., Reeve, A. E., Leppert, M., Strong, L. C., Douglass, E. C., Geiser, C. F., Li, F. P., Meadows, A., Callen, D. F., Lenoir, G. & Saunders, G. F. (1992) Cancer Res. 52, 6117-6120.
6. Haber, D. A., Sohn, R. L., Buckler, A. J., Pelletier, J., Call, K. M. & Housman, D. E. (1991) Proc. Natl. Acad. Sci. USA 88, 9618-9622.
7. Brenner, B., Wildhardt, G., Schneider, S. & Royer-Pokora, B. (1992) Oncogene 7, 1431-1433.
8. Rauscher, F. J., Morris, J. F., Tournay, O. E., Cook, D. M. & Curran, T. (1990) Science 250, 1259-1262.
9. Wang, Z. Y., Qiu, O. Q., Huang, J., Gurrieri, M. & Deuel, T. F. (1995) Oncogene 10, 415-422.
10. Wang, Z. Y., Qiu, Q. Q., Enger, K. T. & Deuel. T. F. (1993) Proc. Natl. Acad. Sci. USA 90, 8896-8900.
11. Wang, Z. Y., Qiu, Q. Q. & Deuel, T. F. (1993) J. Biol. Chem. 268, 9172-9175.
12. Hastie, N. D. (1994) Annu. Rev. Genet. 28, 523-558.
13. Pritchard-Jones, K., Fleming, S., Davidson, D., Bickmore, W., Porteous, D., Gosden, C., Bard, J., Buckler, A., Pelletier, J., Husman, D., van Heyningen, V. & Hastie, N. (1990) Nature (London) 346, 194-197.
14. Pelletier, J., Bruening, W., Li, F. P., Haber, D. A., Glaser, T. & Housman, D. E. (1991) Nature (London) 353, 431-434.
15. Pritchard-Jones, K. & Fleming, S. (1991) Oncogene 6, 2211-2220.
16. Mundlos, S., Pelletier, J., Darveau, A., Bachmann, M., Winterpracht, A. & Zabel, B. (1993) Development (Cambridge, U.K.) 119, 1329-1341.
17. Huang, A., Campbell, C. E., Bonetta, L., McAndrews-Hill, M. S., Chilton-McNeill, S., Coppes, M. J., Law, D. J., Feinberg, A. P., Yeger, H. & Williams, B. R. G. (1990) Science 250, 991-994.
18. Gerald, W. L., Gramling, T. S., Sens, D. A. & Garvin A. J. (1992) Am. J. Pathol. 140, 1031-1037.
19. Miwa, H., Tomlinson, G. E., Timmons, C. F., Huff, V., Cohn, S. L., Strong, L. C. & Saunders, G. F. (1992) J. Natl. Cancer Inst. 84, 181-187.
20. Yeger, H., Culliane, C., Flenniken, A., Chilton-MacNeill, S., Campbell, C., Huang, A., Bonetta, L., Coppes, M. J., Thorner, P. & Williams, B. R. G. (1992) Cell Growth Differ. 3, 855-864.
21. Beckwith, J. B., Kiviat, N. B. & Bonadio, J. F. (1990) Pediatr. Pathol. 10, 1-36.
22. Mierau, G. W., Beckwith, J. B. & Weeks, D. A. (1987) Ultrastruct. Pathol. 11, 313-333.
23. Ludwig, R., Weirich, A., Pötter, R., Harms, D., Bürger, D., Michaelis, J., Erttmann, R., Weinel, P., Haas, R. J., Ritter, J. M. & Jacobi, H. (1992) Klin. Pädiatr. 204, 204-213.
24. Weirich, A., Schmidt, D., Harms, D. & Ludwig, R. (1994) Med. Pediatr. Oncol. 23, 217 (abstr.).
25. Royer-Pokora, B. & Schneider, S. (1992) Genes Chromosomes Cancer 5, 132-140.
26. Kunkel, L. M., Smith, K. D., Boyer, S. H., Borgaonkar, D. S., Wachtel, S. S., Miller, O. J., Breg, W. R., Jones, H. W., Jr., & Rary, J. M. (1977) Proc. Natl. Acad. Sci. USA 74, 1245-1249.
27. Pelletier, J., Bruening, W., Kashtan, C. E., Mauer, S. M., Manivel, J. C., Striegel, J. E., Houghton, D. C., Junien, C., Habib, R., Fouser, L., Fine, R. N., Silverman, B. L., Haber, D. A. & Housman, D. (1991) Cell 67, 437-447.
28. Bruening, W., Bardeesy, N., Silverman, B. L., Cohn, R. A., Machin, G. A., Aronson, A. J., Housman, D. & Pelletier, J. (1992) Nat. Genet. 1, 144-148.
29. Bruening, W., Gros, P., Sato, T., Stanimir, J., Nakamura, Y., Housman, D. & Pelletier, J. (1993) Cancer Invest. 11, 393-399.
30. Schneider, S., Wildhardt, G., Ludwig, R. & Royer-Pokora, B. (1993) Hum. Genet. 91, 599-604.
31. Groves, N., Baird, P. N., Hogg, A. & Cowell, J. K. (1992) Hum. Genet. 90, 440-442.
32. Haber, D. A., Buckler, A. J., Glaser, T., Call, K. M., Pelletier, J., Sohn, R. L., Douglass, E. C. & Housman, D. E. (1990) Cell 61, 1257-1266.
33. Royer-Pokora, B., Ragg, S., Heckl-Östreicher, B., Held, M., Loos, U., Call, K., Glaser, T., Housman, D., Saunders, G., Zabel, B., Williams, B. & Poustka, A. (1991) Genes Chromosomes Cancer 3, 89-100.
34. Drechsler, M., Meijers-Heijboer, E. J., Schneider, S., Schurich, B., Grond-Ginsbach, C., Tariverdian, G., Kantner, G., Blankenagel, A., Kaps, D., Schroeder-Kurth, T. & Royer-Pokora, B. (1994) Hum. Genet. 94, 331-338.
35. Orita, M., Suzuki, Y., Sekiya, T. & Hayashi, K. (1989) Genomics 5, 874-879.
36. Varanasi, R., Bardeesy, N., Ghahremani, M., Petruzzi, M. J., Nowak, N., Adam, M. A., Grundy, P., Shows, T. B. & Pelletier, J. (1994) Proc. Natl. Acad. Sci. USA 91, 3554-3558.
37. Gessler, M., König, A., Arden, K., Grundy, P., Orkin, S., Sallan, S., Peters, C., Ruyle, S., Mandell, J., Li, F., Cavenee, W. & Bruns, G. (1994) Hum. Mutat. 3, 212-222.
38. Moffett, P., Bruening, W., Nakagama, H., Bardeesy, N., Housman, D. E. & Pelletier, J. (1995) Proc. Natl. Acad. Sci. USA 92, 11105-11109.
39. Spirio, L., Olschwang, S., Groden, J., Roberston, M., Samowitz, W., Joslyn, G., Gelbert, L., Thiliveris, A., Carlson, M., Otterud, B., Lynch, H., Watson, P., Lynch, P., Laureut-Puig, P., Burt, R., Hughes, J. P., Thomas, G., Leppert, M. & White, R. (1993) Cell 75, 951-957.
40. Huff, V., Jaffe, N., Saunders, G. F., Strong, L. C., Villalba, F. & Ruteshouser, E. C. (1995) Am. J. Hum. Genet. 56, 84-90.
41. Krawczak, M. & Cooper, D. N. (1991) Hum. Genet. 86, 425-441.
42. Little, M. H., Prosser, J., Condie, A., Smith, P. J., Van Heyningen, V. & Hastie, N. D. (1992) Proc. Natl. Acad. Sci. USA 89, 4791-4795.
43. Quek, H. H., Chow, V. T. & Tock, E. (1993) Anticancer Res. 13, 1575-1580.
44. Caron de Fromentel, C. & Soussi, T. (1992) Genes Chromosomes Cancer 4, 1-15.
45. Knudson, A. G. & Strong, L. C. (1972) J. Natl. Cancer Inst. 48, 313-324.
46. Ludwig, R., Weind, A., Bürger, D., Graf, N., Harms, D., Kaatsch, P., Pötter, R., Rieden, K., Tröger, J. & Zimmermann, H. (1997) Monatsschr. Kinderheilkd. 145, 128-135.