Targeted gene knockout in chickens mediated by TALENs

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 35, 2014, Pages 12716-12721

  Park, Tae Sub ^a,b   Lee, Hong Jo ^a   Kim, Ki Hyun ^a   Kim, Jin Soo ^b   Han, Jae Yong ^a  

^a Seoul National University   (South Korea)

^b Seoul National University   (South Korea)

Author keywords

Egg protein; Genetic modification; Germ line chimera; Poultry; Programmable genome editing

Indexed keywords

DNA; OVALBUMIN; TRANSCRIPTION ACTIVATOR LIKE EFFECTOR NUCLEASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL PROLIFERATION; CHICKEN; CHICKEN MODEL; CONTROLLED STUDY; DNA SEQUENCE; DOUBLE STRANDED DNA BREAK; EMBRYO; FEMALE; GENE INACTIVATION; GENE TARGETING; INDUCED MUTATION; MALE; NONHUMAN; PRIMORDIAL GERM CELL; PRIORITY JOURNAL; PROGENY; SEXUAL MATURATION; TRANSGENIC ANIMAL; TRANSGENIC CHICKEN; TRANSIENT TRANSFECTION; TRANSLATION INITIATION;

EGG PROTEIN; GENETIC MODIFICATION; GERM-LINE CHIMERA; POULTRY; PROGRAMMABLE GENOME EDITING;

ANIMALS; BASE SEQUENCE; CELL LINE; CHICKENS; CHIMERA; EGG PROTEINS; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENE KNOCKDOWN TECHNIQUES; GENETIC ENGINEERING; GENOMICS; GERM CELLS; GERM-LINE MUTATION; LUMINESCENT PROTEINS; MALE; MOLECULAR SEQUENCE DATA; OVALBUMIN; POULTRY; TRANSCRIPTION, GENETIC; TRANSGENES;

EID: 84907228025     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1410555111     Document Type: Article

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