메뉴 건너뛰기




Volumn 31, Issue 5, 2014, Pages 465-482

Microbial production of plant specialized metabolites

Author keywords

Alkaloids; Flavonoids; Phenylpropanoids; Synthetic biology; Terpenoids

Indexed keywords


EID: 84923410129     PISSN: 13424580     EISSN: 13476114     Source Type: Journal    
DOI: 10.5511/plantbiotechnology.14.1003a     Document Type: Review
Times cited : (15)

References (141)
  • 1
    • 77953053139 scopus 로고    scopus 로고
    • Structure and function of the chalcone synthase superfamily of plant type III polyketide synthases
    • Abe I, Morita H (2010) Structure and function of the chalcone synthase superfamily of plant type III polyketide synthases. Aat Prod Rep 27: 809-838
    • (2010) Aat Prod Rep , vol.27 , pp. 809-838
    • Abe, I.1    Morita, H.2
  • 2
    • 12044254693 scopus 로고
    • Enzymatic cyclization of squalene and oxidosqualene to sterols and triterpenes
    • Abe I, Rohmer M, Prestwich GD (1993) Enzymatic cyclization of squalene and oxidosqualene to sterols and triterpenes. Chem Rev 93: 2189-2206
    • (1993) Chem Rev , vol.93 , pp. 2189-2206
    • Abe, I.1    Rohmer, M.2    Prestwich, G.D.3
  • 4
    • 0033230703 scopus 로고    scopus 로고
    • Cloning and functional expression of a cytochrome P450 cDNA encoding 2-hydroxyisoflavanone synthase involved in biosynthesis of the isoflavonoid skeleton in licorice
    • Akashi T, Aoki T, Ayabe S (1999) Cloning and functional expression of a cytochrome P450 cDNA encoding 2-hydroxyisoflavanone synthase involved in biosynthesis of the isoflavonoid skeleton in licorice. Plant Physiol 121: 821-828
    • (1999) Plant Physiol , vol.121 , pp. 821-828
    • Akashi, T.1    Aoki, T.2    Ayabe, S.3
  • 6
    • 64749098176 scopus 로고    scopus 로고
    • Search extension transforms Wiki into a relational system: A case for flavonoid metabolite database
    • Arita M, Suwa K (2008) Search extension transforms Wiki into a relational system: a case for flavonoid metabolite database. BioData Min 1: 7
    • (2008) Biodata Min , vol.1 , pp. 7
    • Arita, M.1    Suwa, K.2
  • 7
    • 70449592325 scopus 로고    scopus 로고
    • Enhancing sesquiterpene production in Saccharomyces cerevisiae through in silico driven metabolic engineering
    • Asadollahi MA, Maury J, Patil KR, Schalk M, Clark A, Nielsen J (2009) Enhancing sesquiterpene production in Saccharomyces cerevisiae through in silico driven metabolic engineering. Metab Eng 11: 328-334
    • (2009) Metab Eng , vol.11 , pp. 328-334
    • Asadollahi, M.A.1    Maury, J.2    Patil, K.R.3    Schalk, M.4    Clark, A.5    Nielsen, J.6
  • 10
    • 43549105634 scopus 로고    scopus 로고
    • Terpenoid biomaterials
    • Bohlmann J, Keeling CI (2008) Terpenoid biomaterials. Plant J 54: 656-669
    • (2008) Plant J , vol.54 , pp. 656-669
    • Bohlmann, J.1    Keeling, C.I.2
  • 11
    • 84864148741 scopus 로고    scopus 로고
    • Discovery and functional characterization of two diterpene synthases for sclareol biosynthesis in Salvia sclarea (L.) and their relevance for perfume manufacture
    • Caniard A, Zerbe P, Legrand S, Cohade A, Valot N, Magnard JL, Bohlmann J, Legendre L (2012) Discovery and functional characterization of two diterpene synthases for sclareol biosynthesis in Salvia sclarea (L.) and their relevance for perfume manufacture. BMC Plant Biol 12: 119
    • (2012) BMC Plant Biol , vol.12 , pp. 119
    • Caniard, A.1    Zerbe, P.2    Legrand, S.3    Cohade, A.4    Valot, N.5    Magnard, J.L.6    Bohlmann, J.7    Legendre, L.8
  • 12
    • 0141794487 scopus 로고    scopus 로고
    • Monoterpene biosynthesis pathway construction in Escherichia coli
    • Carter OA, Peters RJ, Croteau R (2003) Monoterpene biosynthesis pathway construction in Escherichia coli. Phytochemistry 64: 425-433
    • (2003) Phytochemistry , vol.64 , pp. 425-433
    • Carter, O.A.1    Peters, R.J.2    Croteau, R.3
  • 13
    • 34247182988 scopus 로고    scopus 로고
    • Engineering Escherichia coli for production of functionalized terpenoids using plant P450s
    • Chang MCY, Eachus RA, Trieu W, Ro DK, Keasling JD (2007). Engineering Escherichia coli for production of functionalized terpenoids using plant P450s. Aat Chem Biol 3: 274-277
    • (2007) Aat Chem Biol , vol.3 , pp. 274-277
    • Chang, M.1    Eachus, R.A.2    Trieu, W.3    Ro, D.K.4    Keasling, J.D.5
  • 14
    • 33751120932 scopus 로고    scopus 로고
    • Production of isoprenoid pharmaceuticals by engineered microbes
    • Chang MCY, Keasling JD (2006) Production of isoprenoid pharmaceuticals by engineered microbes. Aat Chem Biol 2:674-681
    • (2006) Aat Chem Biol , vol.2 , pp. 674-681
    • Chang, M.1    Keasling, J.D.2
  • 15
    • 57649100762 scopus 로고    scopus 로고
    • Metabolic engineering for plant natural product biosynthesis in microbes
    • Chemler JA, Koffas MA (2008) Metabolic engineering for plant natural product biosynthesis in microbes. Curr Opin Biotechnol 19: 597-605
    • (2008) Curr Opin Biotechnol , vol.19 , pp. 597-605
    • Chemler, J.A.1    Koffas, M.A.2
  • 16
    • 84862908469 scopus 로고    scopus 로고
    • Membrane protein complexes catalyze both 4-and 3-hydroxylation of cinnamic acid derivatives in monolignol biosynthesis
    • Chen HC, Li Q, Shuford CM, Liu J, Muddiman DC, Sederoff RR, Chiang VL (2011) Membrane protein complexes catalyze both 4-and 3-hydroxylation of cinnamic acid derivatives in monolignol biosynthesis. Proc Natl Acad Sci USA 108: 21253-21258
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 21253-21258
    • Chen, H.C.1    Li, Q.2    Shuford, C.M.3    Liu, J.4    Muddiman, D.C.5    Sederoff, R.R.6    Chiang, V.L.7
  • 17
    • 81055140628 scopus 로고    scopus 로고
    • Biosynthesis of plant-specific phenylpropanoids by construction of an artificial biosynthetic pathway in Escherichia coli
    • Choi O, Wu CZ, Kang SY, Ahn JS, Uhm TB, Hong YS (2011) Biosynthesis of plant-specific phenylpropanoids by construction of an artificial biosynthetic pathway in Escherichia coli. J Ind Microbiol Biotechnol 38: 1657-1665
    • (2011) J Ind Microbiol Biotechnol , vol.38 , pp. 1657-1665
    • Choi, O.1    Wu, C.Z.2    Kang, S.Y.3    Ahn, J.S.4    Uhm, T.B.5    Hong, Y.S.6
  • 18
    • 84874095104 scopus 로고    scopus 로고
    • Self-assembly of synthetic metabolons through synthetic protein scaffolds: One-step purification, co-immobilization, and substrate channeling
    • Chun Y, Zhang Y-HP (2013) Self-assembly of synthetic metabolons through synthetic protein scaffolds: one-step purification, co-immobilization, and substrate channeling. ACS Synth Biol 2: 102-110
    • (2013) ACS Synth Biol , vol.2 , pp. 102-110
    • Chun, Y.1    Zhang, Y.-H.P.2
  • 20
    • 84900873278 scopus 로고    scopus 로고
    • Optimization of a yeast RNA interference system for controlling gene expression and enabling rapid metabolic engineering
    • Crook NC, Schmitz AC, Alper HS (2014) Optimization of a yeast RNA interference system for controlling gene expression and enabling rapid metabolic engineering. ACS Synth Biol 3: 307-313
    • (2014) ACS Synth Biol , vol.3 , pp. 307-313
    • Crook, N.C.1    Schmitz, A.C.2    Alper, H.S.3
  • 21
    • 84923423858 scopus 로고    scopus 로고
    • Design of synthetic yeast promoters via tuning of nucleosome architecture. Nat Commun 5: 4002 Cushnie TPT, Lamb AJ (2011) Recent advances in understanding the antibacterial properties of flavonoids
    • Curran KA, Crook NC, Karim AS, Gupta A, Wagman AM, Alper HS (2014) Design of synthetic yeast promoters via tuning of nucleosome architecture. Nat Commun 5: 4002 Cushnie TPT, Lamb AJ (2011) Recent advances in understanding the antibacterial properties of flavonoids. Int J Antimicrob Agents 38: 99-107
    • (2014) Int J Antimicrob Agents , vol.38 , pp. 99-107
    • Curran, K.A.1    Crook, N.C.2    Karim, A.S.3    Gupta, A.4    Wagman, A.M.5    Alper, H.S.6
  • 22
    • 34249815814 scopus 로고    scopus 로고
    • A modular approach for facile biosynthesis of labdane-related diterpenes
    • Cyr A, Wilderman PR, Determan M, Peters RJ (2007) A modular approach for facile biosynthesis of labdane-related diterpenes. J Am Chem Soc 129: 6684-6685
    • (2007) J am Chem Soc , vol.129 , pp. 6684-6685
    • Cyr, A.1    Wilderman, P.R.2    Determan, M.3    Peters, R.J.4
  • 24
    • 84866744325 scopus 로고    scopus 로고
    • Production of miltiradiene by metabolically engineered Saccharomyces cerevisiae
    • Dai Z, Liu Y, Huang L, Zhang X (2012) Production of miltiradiene by metabolically engineered Saccharomyces cerevisiae. Biotechnol Bioeng 109: 2845-2853
    • (2012) Biotechnol Bioeng , vol.109 , pp. 2845-2853
    • Dai, Z.1    Liu, Y.2    Huang, L.3    Zhang, X.4
  • 26
    • 77957735770 scopus 로고    scopus 로고
    • Flavonoids and isoflavonoids: From plant biology to agriculture and neuroscience
    • Dixon RA, Pasinetti GM (2010) Flavonoids and isoflavonoids: from plant biology to agriculture and neuroscience. Plant Physiol 154: 453-457
    • (2010) Plant Physiol , vol.154 , pp. 453-457
    • Dixon, R.A.1    Pasinetti, G.M.2
  • 27
    • 80051704380 scopus 로고    scopus 로고
    • Engineering microbial factories for synthesis of value-added products
    • Du J, Shao Z, Zhao H (2011) Engineering microbial factories for synthesis of value-added products. J Ind Microbiol Biotechnol 38: 873-890
    • (2011) J Ind Microbiol Biotechnol , vol.38 , pp. 873-890
    • Du, J.1    Shao, Z.2    Zhao, H.3
  • 28
    • 84865278051 scopus 로고    scopus 로고
    • Customized optimization of metabolic pathways by combinatorial transcriptional engineering
    • Du J, Yuan Y, Si T, Lian J, Zhao H (2012) Customized optimization of metabolic pathways by combinatorial transcriptional engineering. Nucleic Acids Res 40: e142
    • (2012) Nucleic Acids Res , vol.40
    • Du, J.1    Yuan, Y.2    Si, T.3    Lian, J.4    Zhao, H.5
  • 29
    • 44749083814 scopus 로고    scopus 로고
    • Metabolic engineering of taxadiene biosynthesis in yeast as a first step towards taxol (Paclitaxel) production
    • Engels B, Dahm P, Jennewein S (2008) Metabolic engineering of taxadiene biosynthesis in yeast as a first step towards taxol (paclitaxel) production. Metab Eng 10: 201-206
    • (2008) Metab Eng , vol.10 , pp. 201-206
    • Engels, B.1    Dahm, P.2    Jennewein, S.3
  • 33
    • 67650660144 scopus 로고    scopus 로고
    • Increased malonyl coenzyme A biosynthesis by tuning the Escherichia coli metabolic network and its application to flavanone production
    • Fowler ZL, Gikandi WW, Koffas MAG (2009) Increased malonyl coenzyme A biosynthesis by tuning the Escherichia coli metabolic network and its application to flavanone production. Appl Environ Microbiol 75: 5831-5839
    • (2009) Appl Environ Microbiol , vol.75 , pp. 5831-5839
    • Fowler, Z.L.1    Gikandi, W.W.2    Koffas, M.3
  • 34
    • 77952550033 scopus 로고    scopus 로고
    • Cloning and characterization of a novel gene that encodes (S)-//-bisabolene synthase from ginger
    • Fujisawa M, Harada H, Kenmoku H, Mizutani S, Misawa N (2010) Cloning and characterization of a novel gene that encodes (S)-//-bisabolene synthase from ginger, Zingiber officinale. Planta 232: 121-130
    • (2010) Zingiber Officinale. Planta , vol.232 , pp. 121-130
    • Fujisawa, M.1    Harada, H.2    Kenmoku, H.3    Mizutani, S.4    Misawa, N.5
  • 36
    • 70749152711 scopus 로고    scopus 로고
    • A functional genomics approach to tanshinone biosynthesis provides stereochemical insights
    • Gao W, Hillwig ML, Huang L, Cui G, Wang X, Kong J, Yang B, Peters RJ (2009) A functional genomics approach to tanshinone biosynthesis provides stereochemical insights. Org Lett 11: 5170-5173
    • (2009) Org Lett , vol.11 , pp. 5170-5173
    • Gao, W.1    Hillwig, M.L.2    Huang, L.3    Cui, G.4    Wang, X.5    Kong, J.6    Yang, B.7    Peters, R.J.8
  • 37
    • 68349157140 scopus 로고    scopus 로고
    • Identification, functional characterization and developmental regulation of sesquiterpene synthases from sunflower capitate glandular trichomes
    • Gôpfert JC, Macnevin G, Ro DK, Spring O (2009) Identification, functional characterization and developmental regulation of sesquiterpene synthases from sunflower capitate glandular trichomes. BMC Plant Biol 9: 86
    • (2009) BMC Plant Biol , vol.9 , pp. 86
    • Gôpfert, J.C.1    Macnevin, G.2    Ro, D.K.3    Spring, O.4
  • 38
    • 84887978889 scopus 로고    scopus 로고
    • Bio-based solvents: An emerging generation of fluids for the design of eco-efficient processes in catalysis and organic chemistry
    • Gu Y, Jérôme F (2013) Bio-based solvents: an emerging generation of fluids for the design of eco-efficient processes in catalysis and organic chemistry. Chem Soc Rev 42: 9550-9570
    • (2013) Chem Soc Rev , vol.42 , pp. 9550-9570
    • Gu, Y.1    Jérôme, F.2
  • 39
    • 84880380223 scopus 로고    scopus 로고
    • CYP76AH1 catalyzes turnover of miltiradiene in tanshinones biosynthesis and enables heterologous production of ferruginol in yeasts
    • Guo J, Zhou YJ, Hillwig ML, Shen Y, Yang L, Wang Y, Zhang X, Liu W, Peters RJ, Chen X, et al. (2013) CYP76AH1 catalyzes turnover of miltiradiene in tanshinones biosynthesis and enables heterologous production of ferruginol in yeasts. Proc Natl Acad Sci USA 110: 12108-12113
    • (2013) Proc Natl Acad Sci USA , vol.110 , pp. 12108-12113
    • Guo, J.1    Zhou, Y.J.2    Hillwig, M.L.3    Shen, Y.4    Yang, L.5    Wang, Y.6    Zhang, X.7    Liu, W.8    Peters, R.J.9    Chen, X.10
  • 40
    • 82855167372 scopus 로고    scopus 로고
    • Evolution of diterpene metabolism: Sitka spruce CYP720B4 catalyzes multiple oxidations in resin acid biosynthesis of conifer defense against insects
    • Hamberger B, Ohnishi T, Hamberger B, Seguin A, Bohlmann J (2011) Evolution of diterpene metabolism: Sitka spruce CYP720B4 catalyzes multiple oxidations in resin acid biosynthesis of conifer defense against insects. Plant Physiol 157: 1677-1695
    • (2011) Plant Physiol , vol.157 , pp. 1677-1695
    • Hamberger, B.1    Ohnishi, T.2    Hamberger, B.3    Seguin, A.4    Bohlmann, J.5
  • 41
    • 49949088247 scopus 로고    scopus 로고
    • Production of benzylisoquinoline alkaloids in Saccharomyces cerevisiae
    • Hawkins KM, Smolke CD (2008) Production of benzylisoquinoline alkaloids in Saccharomyces cerevisiae. Nat Chem Biol 4: 564-573
    • (2008) Nat Chem Biol , vol.4 , pp. 564-573
    • Hawkins, K.M.1    Smolke, C.D.2
  • 42
    • 39849106151 scopus 로고    scopus 로고
    • Engineering the Saccharomyces cerevisiae isoprenoid pathway for de novo production of aromatic monoterpenes in wine
    • Herrero Ó, Ramón D, Orejas M (2008) Engineering the Saccharomyces cerevisiae isoprenoid pathway for de novo production of aromatic monoterpenes in wine. Metab Eng 10: 78-86
    • (2008) Metab Eng , vol.10 , pp. 78-86
    • Herrero, Ó.1    Ramón, D.2    Orejas, M.3
  • 43
    • 0034838359 scopus 로고    scopus 로고
    • Engineering Escherichia coli for the synthesis of taxadiene, a key intermediate in the biosynthesis of taxol
    • Huang Q, Roessner CA, Croteau R, Scott AI (2001) Engineering Escherichia coli for the synthesis of taxadiene, a key intermediate in the biosynthesis of taxol. Bioorg Med Chem 9: 2237-2242
    • (2001) Bioorg Med Chem , vol.9 , pp. 2237-2242
    • Huang, Q.1    Roessner, C.A.2    Croteau, R.3    Scott, A.I.4
  • 44
    • 0033621061 scopus 로고    scopus 로고
    • New routes for lignin biosynthesis defined by biochemical characterization of recombinant ferulate 5-hydroxylase, a multifunctional cytochrome P450-dependent monooxygenase
    • Humphreys JM, Hemm MR, Chapple C (1999) New routes for lignin biosynthesis defined by biochemical characterization of recombinant ferulate 5-hydroxylase, a multifunctional cytochrome P450-dependent monooxygenase. Proc Natl Acad Sci USA 96: 10045-10050
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 10045-10050
    • Humphreys, J.M.1    Hemm, M.R.2    Chapple, C.3
  • 45
    • 0037545559 scopus 로고    scopus 로고
    • Production of plant-specific flavanones by Escherichia coli containing an artificial gene cluster
    • Hwang EI, Kaneko M, Ohnishi Y, Horinouchi S (2003) Production of plant-specific flavanones by Escherichia coli containing an artificial gene cluster. Appl Environ Microbiol 69: 2699-2706
    • (2003) Appl Environ Microbiol , vol.69 , pp. 2699-2706
    • Hwang, E.I.1    Kaneko, M.2    Ohnishi, Y.3    Horinouchi, S.4
  • 46
    • 84899936225 scopus 로고    scopus 로고
    • Three gene expression vector sets for concurrently expressing multiple genes in Saccharomyces cerevisiae
    • Ishii J, Kondo T, Makino H, Ogura A, Matsuda F, Kondo A (2014) Three gene expression vector sets for concurrently expressing multiple genes in Saccharomyces cerevisiae. FEMS Yeast Res 14: 399-411
    • (2014) FEMS Yeast Res , vol.14 , pp. 399-411
    • Ishii, J.1    Kondo, T.2    Makino, H.3    Ogura, A.4    Matsuda, F.5    Kondo, A.6
  • 47
    • 84888844326 scopus 로고    scopus 로고
    • Characterization of five terminator regions that increase the protein yield of a transgene in Saccharomyces cerevisiae
    • Ito Y, Yamanishi M, Ikeuchi A, Imamura C, Tokuhiro K, Kitagawa T, Matsuyama T (2013) Characterization of five terminator regions that increase the protein yield of a transgene in Saccharomyces cerevisiae. J Biotechnol 168: 486-492
    • (2013) J Biotechnol , vol.168 , pp. 486-492
    • Ito, Y.1    Yamanishi, M.2    Ikeuchi, A.3    Imamura, C.4    Tokuhiro, K.5    Kitagawa, T.6    Matsuyama, T.7
  • 48
    • 0041728804 scopus 로고    scopus 로고
    • Metabolic engineering to produce sesquiterpenes in yeast
    • Jackson BE, Hart-Wells EA, Matsuda SPT (2003) Metabolic engineering to produce sesquiterpenes in yeast. Org Lett 5: 1629-1632
    • (2003) Org Lett , vol.5 , pp. 1629-1632
    • Jackson, B.E.1    Hart-Wells, E.A.2    Matsuda, S.3
  • 49
    • 84919385298 scopus 로고    scopus 로고
    • Metabolic engineering for p-coumaryl alcohol production in Escherichia coli by introducing an artificial phenylpropanoid pathway
    • in press
    • Jansen F, Gillessen B, Mueller F, Commandeur U, Fischer R, Kreuzaler F (2014) Metabolic engineering for p-coumaryl alcohol production in Escherichia coli by introducing an artificial phenylpropanoid pathway. Biotechnol Appl Biochem, in press
    • (2014) Biotechnol Appl Biochem
    • Jansen, F.1    Gillessen, B.2    Mueller, F.3    Commandeur, U.4    Fischer, R.5    Kreuzaler, F.6
  • 50
    • 84862277234 scopus 로고    scopus 로고
    • Metabolic engineering of yeast and plants for the production of the biologically active hydroxystilbene, resveratrol
    • Jeandet P, Delaunois B, Aziz A, Donnez D, Vasserot Y, Cordelier S, Courot E (2012) Metabolic engineering of yeast and plants for the production of the biologically active hydroxystilbene, resveratrol. J Biomed Biotechnol 2012: 579-589
    • (2012) J Biomed Biotechnol , vol.2012 , pp. 579-589
    • Jeandet, P.1    Delaunois, B.2    Aziz, A.3    Donnez, D.4    Vasserot, Y.5    Cordelier, S.6    Courot, E.7
  • 51
    • 20444422841 scopus 로고    scopus 로고
    • Metabolic engineering of the phenylpropanoid pathway in Saccharomyces cerevisiae
    • Jiang H, Wood KV, Morgan JA (2005) Metabolic engineering of the phenylpropanoid pathway in Saccharomyces cerevisiae. Appl Environ Microbiol 71: 2962-2969
    • (2005) Appl Environ Microbiol , vol.71 , pp. 2962-2969
    • Jiang, H.1    Wood, K.V.2    Morgan, J.A.3
  • 53
    • 84870293949 scopus 로고    scopus 로고
    • Artificial biosynthesis of phenylpropanoic acids in a tyrosine overproducing Escherichia coli strain
    • Kang SY, Choi O, Lee JK, Hwang BY, Uhm TB, Hong YS (2012) Artificial biosynthesis of phenylpropanoic acids in a tyrosine overproducing Escherichia coli strain. Microb Cell Fact 11: 153
    • (2012) Microb Cell Fact , vol.11 , pp. 153
    • Kang, S.Y.1    Choi, O.2    Lee, J.K.3    Hwang, B.Y.4    Uhm, T.B.5    Hong, Y.S.6
  • 54
    • 35748972666 scopus 로고    scopus 로고
    • Precursor-directed biosynthesis of stilbene methyl ethers in Escherichia coli
    • Katsuyama Y, Funa N, Horinouchi S (2007a) Precursor-directed biosynthesis of stilbene methyl ethers in Escherichia coli. Biotechnol J 2: 1286-1293
    • (2007) Biotechnol J , vol.2 , pp. 1286-1293
    • Katsuyama, Y.1    Funa, N.2    Horinouchi, S.3
  • 55
    • 34250304606 scopus 로고    scopus 로고
    • Synthesis of unnatural flavonoids and stilbenes by exploiting the plant biosynthetic pathway in Escherichia coli
    • Katsuyama Y, Funa N, Miyahisa I, Horinouchi S (2007b) Synthesis of unnatural flavonoids and stilbenes by exploiting the plant biosynthetic pathway in Escherichia coli. Chem Biol 14: 613-621
    • (2007) Chem Biol , vol.14 , pp. 613-621
    • Katsuyama, Y.1    Funa, N.2    Miyahisa, I.3    Horinouchi, S.4
  • 56
    • 33845793496 scopus 로고    scopus 로고
    • One-pot synthesis of genistein from tyrosine by coincubation of genetically engineered Escherichia coli and Saccharomyces cerevisiae cells
    • Katsuyama Y, Miyahisa I, Funa N, Horinouchi S (2007c) One-pot synthesis of genistein from tyrosine by coincubation of genetically engineered Escherichia coli and Saccharomyces cerevisiae cells. Appl Microbiol Biotechnol 73: 1143-1149
    • (2007) Appl Microbiol Biotechnol , vol.73 , pp. 1143-1149
    • Katsuyama, Y.1    Miyahisa, I.2    Funa, N.3    Horinouchi, S.4
  • 57
    • 53449086128 scopus 로고    scopus 로고
    • Production of curcuminoids by Escherichia coli carrying an artificial biosynthesis pathway
    • Katsuyama Y, Matsuzawa M, Funa N, Horinouchi S (2008) Production of curcuminoids by Escherichia coli carrying an artificial biosynthesis pathway. Microbiology 154: 2620-2628
    • (2008) Microbiology , vol.154 , pp. 2620-2628
    • Katsuyama, Y.1    Matsuzawa, M.2    Funa, N.3    Horinouchi, S.4
  • 58
    • 38749148516 scopus 로고    scopus 로고
    • Synthetic biology for synthetic chemistry
    • Keasling JD (2008) Synthetic biology for synthetic chemistry. ACS Chem Biol 3: 64-76
    • (2008) ACS Chem Biol , vol.3 , pp. 64-76
    • Keasling, J.D.1
  • 59
    • 84859772410 scopus 로고    scopus 로고
    • Synthetic biology and the development of tools for metabolic engineering
    • Keasling JD (2012) Synthetic biology and the development of tools for metabolic engineering. Metab Eng 14: 189-195
    • (2012) Metab Eng , vol.14 , pp. 189-195
    • Keasling, J.D.1
  • 60
    • 80051782754 scopus 로고    scopus 로고
    • Characterization of raspberry ketone/zingerone synthase, catalyzing the alpha, beta-hydrogenation of phenylbutenones in raspberry fruits
    • Koeduka T, Watanabe B, Suzuki S, Hiratake J, Mano J, Yazaki K (2011) Characterization of raspberry ketone/zingerone synthase, catalyzing the alpha, beta-hydrogenation of phenylbutenones in raspberry fruits. Biochem Biophys Res Commun 412: 104-108
    • (2011) Biochem Biophys Res Commun , vol.412 , pp. 104-108
    • Koeduka, T.1    Watanabe, B.2    Suzuki, S.3    Hiratake, J.4    Mano, J.5    Yazaki, K.6
  • 63
    • 58149190072 scopus 로고    scopus 로고
    • Metabolic engineering of microorganisms: General strategies and drug production
    • Lee SY, Kim HU, Park JH, Park JM, Kim TY (2009) Metabolic engineering of microorganisms: general strategies and drug production. Drug Discov Today 14: 78-88
    • (2009) Drug Discov Today , vol.14 , pp. 78-88
    • Lee, S.Y.1    Kim, H.U.2    Park, J.H.3    Park, J.M.4    Kim, T.Y.5
  • 64
    • 56249130054 scopus 로고    scopus 로고
    • Developing an industrial artemisinic acid fermentation process to support the cost-effective production of antimalarial artemisinin-based combination therapies
    • Lenihan JR, Tsuruta H, Diola D, Renninger NS, Regentin R (2008) Developing an industrial artemisinic acid fermentation process to support the cost-effective production of antimalarial artemisinin-based combination therapies. Biotechnol Prog 24: 1026-1032
    • (2008) Biotechnol Prog , vol.24 , pp. 1026-1032
    • Lenihan, J.R.1    Tsuruta, H.2    Diola, D.3    Renninger, N.S.4    Regentin, R.5
  • 65
    • 36649037393 scopus 로고    scopus 로고
    • Engineering of artificial plant cytochrome P450 enzymes for synthesis of isoflavones by Escherichia coli
    • Leonard E, Koffas MAG (2007) Engineering of artificial plant cytochrome P450 enzymes for synthesis of isoflavones by Escherichia coli. Appl Environ Microbiol 73: 7246-7251
    • (2007) Appl Environ Microbiol , vol.73 , pp. 7246-7251
    • Leonard, E.1    Koffas, M.2
  • 66
    • 34250849659 scopus 로고    scopus 로고
    • Engineering central metabolic pathways for high-level flavonoid production in Escherichia coli
    • Leonard E, Lim KH, Saw PN, Koffas MAG (2007) Engineering central metabolic pathways for high-level flavonoid production in Escherichia coli. Appl Environ Microbiol 73: 3877-3886
    • (2007) Appl Environ Microbiol , vol.73 , pp. 3877-3886
    • Leonard, E.1    Lim, K.H.2    Saw, P.N.3    Koffas, M.4
  • 67
    • 42549160614 scopus 로고    scopus 로고
    • Strain improvement of recombinant Escherichia coli for efficient production of plant flavonoids
    • Leonard E, Yan Y, Fowler ZL, Li Z, Lim CG, Lim KH, Koffas MAG (2008) Strain improvement of recombinant Escherichia coli for efficient production of plant flavonoids. Mol Pharm 5: 257-265
    • (2008) Mol Pharm , vol.5 , pp. 257-265
    • Leonard, E.1    Yan, Y.2    Fowler, Z.L.3    Li, Z.4    Lim, C.G.5    Lim, K.H.6    Koffas, M.7
  • 68
    • 41549098111 scopus 로고    scopus 로고
    • Production of phenylpropanoid compounds by recombinant microorganisms expressing plant-specific biosynthesis genes
    • Limem I, Guedon E, Hehn A, Bourgaud F, Ghedira LC, Engasser JM, Ghoul M (2008) Production of phenylpropanoid compounds by recombinant microorganisms expressing plant-specific biosynthesis genes. Process Biochem 43: 463-479
    • (2008) Process Biochem , vol.43 , pp. 463-479
    • Limem, I.1    Guedon, E.2    Hehn, A.3    Bourgaud, F.4    Ghedira, L.C.5    Engasser, J.M.6    Ghoul, M.7
  • 69
    • 33644828190 scopus 로고    scopus 로고
    • Cloning and functional analysis of caffeic acid 3-O-methyltransferase from rice (Oryza sativa)
    • Lin F, Yamano G, Hasegawa M, Anzai H, Kawasaki S, Kodama O (2006) Cloning and functional analysis of caffeic acid 3-O-methyltransferase from rice (Oryza sativa). JPestic Sci 31: 47-53
    • (2006) Jpestic Sci , vol.31 , pp. 47-53
    • Lin, F.1    Yamano, G.2    Hasegawa, M.3    Anzai, H.4    Kawasaki, S.5    Kodama, O.6
  • 70
    • 84887242219 scopus 로고    scopus 로고
    • Microbial production of antioxidant food ingredients via metabolic engineering
    • Lin Y, Jain R, Yan Y (2014) Microbial production of antioxidant food ingredients via metabolic engineering. Curr Opin Biotechnol 26: 71-78
    • (2014) Curr Opin Biotechnol , vol.26 , pp. 71-78
    • Lin, Y.1    Jain, R.2    Yan, Y.3
  • 71
    • 84938746622 scopus 로고    scopus 로고
    • Biosynthesis of caffeic acid in Escherichia coli using its endogenous hydroxylase complex
    • Lin Y, Yan Y (2012) Biosynthesis of caffeic acid in Escherichia coli using its endogenous hydroxylase complex. Microb Cell Fact 11: 42
    • (2012) Microb Cell Fact , vol.11 , pp. 42
    • Lin, Y.1    Yan, Y.2
  • 72
    • 42249097714 scopus 로고    scopus 로고
    • Evolutionary and cellular webs in benzylisoquinoline alkaloid biosynthesis
    • Liscombe DK, Facchini PJ (2008) Evolutionary and cellular webs in benzylisoquinoline alkaloid biosynthesis. Curr Opin Biotechnol 19: 173-180
    • (2008) Curr Opin Biotechnol , vol.19 , pp. 173-180
    • Liscombe, D.K.1    Facchini, P.J.2
  • 73
    • 84862940870 scopus 로고    scopus 로고
    • Production of 7-O-methyl aromadendrin, a medicinally valuable flavonoid, in Escherichia coli
    • Malla S, Koffas MAG, Kazlauskas RJ, Kim BG (2012) Production of 7-O-methyl aromadendrin, a medicinally valuable flavonoid, in Escherichia coli. Appl Environ Microbiol 78: 684-694
    • (2012) Appl Environ Microbiol , vol.78 , pp. 684-694
    • Malla, S.1    Koffas, M.2    Kazlauskas, R.J.3    Kim, B.G.4
  • 74
    • 84872172091 scopus 로고    scopus 로고
    • Metabolic engineering of microorganisms for the synthesis of plant natural products
    • Marienhagen J, Bott M (2013) Metabolic engineering of microorganisms for the synthesis of plant natural products. J Biotechnol 163: 166-178
    • (2013) J Biotechnol , vol.163 , pp. 166-178
    • Marienhagen, J.1    Bott, M.2
  • 75
    • 0038391517 scopus 로고    scopus 로고
    • Engineering a mevalonate pathway in Escherichia coli for production of terpenoids
    • Martin VJJ, Pitera DJ, Withers ST, Newman JD, Keasling JD (2003) Engineering a mevalonate pathway in Escherichia coli for production of terpenoids. Nat Biotechnol 21: 796-802
    • (2003) Nat Biotechnol , vol.21 , pp. 796-802
    • Martin, V.1    Pitera, D.J.2    Withers, S.T.3    Newman, J.D.4    Keasling, J.D.5
  • 76
    • 0035814339 scopus 로고    scopus 로고
    • The in vivo synthesis of plant sesquiterpenes by Escherichia coli
    • Martin VJJ, Yoshikuni Y, Keasling JD (2001) The in vivo synthesis of plant sesquiterpenes by Escherichia coli. Biotechnol Bioeng 75: 497-503
    • (2001) Biotechnol Bioeng , vol.75 , pp. 497-503
    • Martin, V.1    Yoshikuni, Y.2    Keasling, J.D.3
  • 78
    • 84861182389 scopus 로고    scopus 로고
    • Efficient conversion of pure and mixed terpene feedstocks to high density fuels
    • Meylemans HA, Quintana RL, Harvey BG (2012) Efficient conversion of pure and mixed terpene feedstocks to high density fuels. Fuel 97: 560-568
    • (2012) Fuel , vol.97 , pp. 560-568
    • Meylemans, H.A.1    Quintana, R.L.2    Harvey, B.G.3
  • 80
    • 79957636478 scopus 로고    scopus 로고
    • Pathway engineering for functional isoprenoids
    • Misawa N (2011) Pathway engineering for functional isoprenoids. Curr Opin Biotechnol 22: 627-633
    • (2011) Curr Opin Biotechnol , vol.22 , pp. 627-633
    • Misawa, N.1
  • 83
    • 77950920131 scopus 로고    scopus 로고
    • Production of novel antioxidative phenolic amides through heterologous expression of the plant's chlorogenic acid biosynthesis genes in yeast
    • Moglia A, Comino C, Lanteri S, de Vos R, de Waard P, van Beek TA, Goitre L, Retta S, Beekwilder J (2010) Production of novel antioxidative phenolic amides through heterologous expression of the plant's chlorogenic acid biosynthesis genes in yeast. Metab Eng 12: 223-232
    • (2010) Metab Eng , vol.12 , pp. 223-232
    • Moglia, A.1    Comino, C.2    Lanteri, S.3    De Vos, R.4    De Waard, P.5    Van Beek, T.A.6    Goitre, L.7    Retta, S.8    Beekwilder, J.9
  • 88
    • 84899051891 scopus 로고    scopus 로고
    • Semi-synthetic artemisinin: A model for the use of synthetic biology in pharmaceutical development
    • Paddon CJ, Keasling JD (2014) Semi-synthetic artemisinin: a model for the use of synthetic biology in pharmaceutical development. Nat Rev Microbiol 12: 355-367
    • (2014) Nat Rev Microbiol , vol.12 , pp. 355-367
    • Paddon, C.J.1    Keasling, J.D.2
  • 90
    • 0034687757 scopus 로고    scopus 로고
    • Abietadiene synthase from grand fir (Abies grandis): Characterization and mechanism of action of the "pseudomature" recombinant enzyme
    • Peters RJ, Flory JE, Jetter R, Ravn MM, Lee HJ, Coates RM, Croteau RB (2000) Abietadiene synthase from grand fir (Abies grandis): Characterization and mechanism of action of the "pseudomature" recombinant enzyme. Biochemistry 39: 15592-15602
    • (2000) Biochemistry , vol.39 , pp. 15592-15602
    • Peters, R.J.1    Flory, J.E.2    Jetter, R.3    Ravn, M.M.4    Lee, H.J.5    Coates, R.M.6    Croteau, R.B.7
  • 91
    • 79955574643 scopus 로고    scopus 로고
    • Convergent evolution in plant specialized metabolism
    • Pichersky E, Lewinsohn E (2011) Convergent evolution in plant specialized metabolism. Annu Rev Plant Biol 62: 549-566
    • (2011) Annu Rev Plant Biol , vol.62 , pp. 549-566
    • Pichersky, E.1    Lewinsohn, E.2
  • 92
    • 33747078696 scopus 로고    scopus 로고
    • Combinatorial engineering of intergenic regions in operons tunes expression of multiple genes
    • Pfleger BF, Pitera DJ, Smolke CD, Keasling JD (2006) Combinatorial engineering of intergenic regions in operons tunes expression of multiple genes. Nat Biotechnol 24: 1027-1032
    • (2006) Nat Biotechnol , vol.24 , pp. 1027-1032
    • Pfleger, B.F.1    Pitera, D.J.2    Smolke, C.D.3    Keasling, J.D.4
  • 93
    • 33847309176 scopus 로고    scopus 로고
    • Balancing a heterologous mevalonate pathway for improved isoprenoid production in Escherichia coli
    • Pitera DJ, Paddon CJ, Newman JD, Keasling JD (2007) Balancing a heterologous mevalonate pathway for improved isoprenoid production in Escherichia coli. Metab Eng 9: 193-207
    • (2007) Metab Eng , vol.9 , pp. 193-207
    • Pitera, D.J.1    Paddon, C.J.2    Newman, J.D.3    Keasling, J.D.4
  • 94
    • 84886249106 scopus 로고    scopus 로고
    • Engineered Escherichia coli as new source of flavonoids and terpenoids
    • Putignani L, Massa O, Alisi A (2013) Engineered Escherichia coli as new source of flavonoids and terpenoids. Food Res Int 54: 1084-1095
    • (2013) Food Res Int , vol.54 , pp. 1084-1095
    • Putignani, L.1    Massa, O.2    Alisi, A.3
  • 95
    • 20444488867 scopus 로고    scopus 로고
    • Partial reconstruction of flavonoid and isoflavonoid biosynthesis in yeast using soybean type I and type II chalcone isomerases
    • Ralston L, Subramanian S, Matsuno M, Yu O (2005) Partial reconstruction of flavonoid and isoflavonoid biosynthesis in yeast using soybean type I and type II chalcone isomerases. Plant Physiol 137: 1375-1388
    • (2005) Plant Physiol , vol.137 , pp. 1375-1388
    • Ralston, L.1    Subramanian, S.2    Matsuno, M.3    Yu, O.4
  • 96
    • 1642576078 scopus 로고    scopus 로고
    • Reconstitution of the entry point of plant phenylpropanoid metabolism in yeast (Saccharomyces cerevisiae): Implications for control of metabolic flux into the phenylpropanoid pathway
    • Ro D-K, Douglas CJ (2004) Reconstitution of the entry point of plant phenylpropanoid metabolism in yeast (Saccharomyces cerevisiae): Implications for control of metabolic flux into the phenylpropanoid pathway. J Biol Chem 279: 2600-2607
    • (2004) J Biol Chem , vol.279 , pp. 2600-2607
    • Ro, D.-K.1    Douglas, C.J.2
  • 97
    • 57049089897 scopus 로고    scopus 로고
    • Induction of multiple pleiotropic drug resistance genes in yeast engineered to produce an increased level of anti-malarial drug precursor, artemisinic acid
    • Ro D-K, Ouellet M, Paradise EM, Burd H, Eng D, Paddon CJ, Newman JD, Keasling JD (2008) Induction of multiple pleiotropic drug resistance genes in yeast engineered to produce an increased level of anti-malarial drug precursor, artemisinic acid. BMC Biotechnol 8: 83
    • (2008) BMC Biotechnol , vol.8 , pp. 83
    • Ro, D.-K.1    Ouellet, M.2    Paradise, E.M.3    Burd, H.4    Eng, D.5    Paddon, C.J.6    Newman, J.D.7    Keasling, J.D.8
  • 100
    • 79958715193 scopus 로고    scopus 로고
    • Optimization of a heterologous pathway for the production of flavonoids from glucose
    • Santos CNS, Koffas M, Stephanopoulos G (2011) Optimization of a heterologous pathway for the production of flavonoids from glucose. Metab Eng 13: 392-400
    • (2011) Metab Eng , vol.13 , pp. 392-400
    • Santos, C.1    Koffas, M.2    Stephanopoulos, G.3
  • 102
    • 65349148463 scopus 로고    scopus 로고
    • Prenylation of flavonoids by biotransformation of yeast expressing plant membrane-boundprenyltransferase SfN8DT-1
    • Sasaki K, Tsurumaru Y, Yazaki K (2009) Prenylation of flavonoids by biotransformation of yeast expressing plant membrane-boundprenyltransferase SfN8DT-1. Biosci Biotechnol Biochem 73: 759-761
    • (2009) Biosci Biotechnol Biochem , vol.73 , pp. 759-761
    • Sasaki, K.1    Tsurumaru, Y.2    Yazaki, K.3
  • 103
    • 84878377588 scopus 로고    scopus 로고
    • Microbial production of isoquinoline alkaloids as plant secondary metabolites based on metabolic engineering research
    • Sato F, Kumagai H (2013) Microbial production of isoquinoline alkaloids as plant secondary metabolites based on metabolic engineering research. Proc Jpn Acad, Ser B, Phys Biol Sci 89: 165-182
    • (2013) Proc Jpn Acad, Ser B, Phys Biol Sci , vol.89 , pp. 165-182
    • Sato, F.1    Kumagai, H.2
  • 104
    • 84892719565 scopus 로고    scopus 로고
    • Triterpenoid biosynthesis and engineering in plants
    • Sawai S, Saito K (2011) Triterpenoid biosynthesis and engineering in plants. Front Plant Sci 2: 25
    • (2011) Front Plant Sci , vol.2 , pp. 25
    • Sawai, S.1    Saito, K.2
  • 107
    • 84880802287 scopus 로고    scopus 로고
    • New insights into the transport mechanisms in plant vacuoles
    • Shitan N, Yazaki K (2013) New insights into the transport mechanisms in plant vacuoles. Int Rev Cell Mol Biol 305: 383-433
    • (2013) Int Rev Cell Mol Biol , vol.305 , pp. 383-433
    • Shitan, N.1    Yazaki, K.2
  • 108
    • 84886389647 scopus 로고    scopus 로고
    • Functional analysis ofjasmonic acid-responsive secondary metabolite transporters
    • Shitan N, Sugiyama A, Yazaki K (2013) Functional analysis ofjasmonic acid-responsive secondary metabolite transporters. Methods Mol Biol 1011: 241-250
    • (2013) Methods Mol Biol , vol.1011 , pp. 241-250
    • Shitan, N.1    Sugiyama, A.2    Yazaki, K.3
  • 109
    • 84857048835 scopus 로고    scopus 로고
    • Advancing secondary metabolite biosynthesis in yeast with synthetic biology tools
    • Siddiqui MS, Thodey K, Trenchard I, Smolke CD (2012) Advancing secondary metabolite biosynthesis in yeast with synthetic biology tools. FEMS Yeast Res 12: 144-170
    • (2012) FEMS Yeast Res , vol.12 , pp. 144-170
    • Siddiqui, M.S.1    Thodey, K.2    Trenchard, I.3    Smolke, C.D.4
  • 110
    • 84897044640 scopus 로고    scopus 로고
    • Recent advances in forest tree biotechnology
    • Suzuki S, Suzuki H (2014) Recent advances in forest tree biotechnology. Plant Biotechnol 31: 1-9
    • (2014) Plant Biotechnol , vol.31 , pp. 1-9
    • Suzuki, S.1    Suzuki, H.2
  • 112
    • 84922067763 scopus 로고    scopus 로고
    • A microbial biomanufacturing platform for natural and semisynthetic opioids
    • Thodey K, Galanie S, Smolke CD (2014) A microbial biomanufacturing platform for natural and semisynthetic opioids. Nat Chem Biol 10: 837-844
    • (2014) Nat Chem Biol , vol.10 , pp. 837-844
    • Thodey, K.1    Galanie, S.2    Smolke, C.D.3
  • 113
    • 70449533072 scopus 로고    scopus 로고
    • Metabolic engineering of the complete pathway leading to heterologous biosynthesis of various flavonoids and stilbenoids in Saccharomyces cerevisiae
    • Trantas E, Panopoulos N, Ververidis F (2009) Metabolic engineering of the complete pathway leading to heterologous biosynthesis of various flavonoids and stilbenoids in Saccharomyces cerevisiae. Metab Eng 11: 355-366
    • (2009) Metab Eng , vol.11 , pp. 355-366
    • Trantas, E.1    Panopoulos, N.2    Ververidis, F.3
  • 115
    • 77949916538 scopus 로고    scopus 로고
    • The cinnamate/monolignol pathway
    • Umezawa T (2010) The cinnamate/monolignol pathway. Phytochem Rev 9: 1-17
    • (2010) Phytochem Rev , vol.9 , pp. 1-17
    • Umezawa, T.1
  • 116
    • 0036898871 scopus 로고    scopus 로고
    • Bioflavours and fragrances via fermentation and biocatalysis
    • Vandamme EJ, Soetaert W (2002) Bioflavours and fragrances via fermentation and biocatalysis. J Chem Technol Biotechnol 77:1323-1332
    • (2002) J Chem Technol Biotechnol , vol.77 , pp. 1323-1332
    • Vandamme, E.J.1    Soetaert, W.2
  • 119
    • 84899150986 scopus 로고    scopus 로고
    • Complete proteomic-based enzyme reaction and inhibition kinetics reveal how monolignol biosynthetic enzyme families affect metabolic flux and lignin in Populus trichocarpa
    • Wang JP, Naik PP, Chen H-C, Shi R, Lin C-Y, Liu J, Shuford CM, Li Q, Sun Y-H, Tunlaya-Anukit S, et al. (2014) Complete proteomic-based enzyme reaction and inhibition kinetics reveal how monolignol biosynthetic enzyme families affect metabolic flux and lignin in Populus trichocarpa. Plant Cell 26: 894-914
    • (2014) Plant Cell , vol.26 , pp. 894-914
    • Wang, J.P.1    Naik, P.P.2    Chen, H.-C.3    Shi, R.4    Lin, C.-Y.5    Liu, J.6    Shuford, C.M.7    Li, Q.8    Sun, Y.-H.9    Tunlaya-Anukit, S.10
  • 120
    • 84863278793 scopus 로고    scopus 로고
    • CYP701A8: A rice ent-kaurene oxidase paralog diverted to more specialized diterpenoid metabolism
    • Wang Q, Hillwig ML, Wu Y, Peters RJ (2012) CYP701A8: A rice ent-kaurene oxidase paralog diverted to more specialized diterpenoid metabolism. Plant Physiol 158: 1418-1425
    • (2012) Plant Physiol , vol.158 , pp. 1418-1425
    • Wang, Q.1    Hillwig, M.L.2    Wu, Y.3    Peters, R.J.4
  • 121
    • 80052644333 scopus 로고    scopus 로고
    • Metabolic engineering of flavonoids in plants and microorganisms
    • Wang Y, Chen S, Yu O (2011a) Metabolic engineering of flavonoids in plants and microorganisms. Appl Microbiol Biotechnol 91: 949-956
    • (2011) Appl Microbiol Biotechnol , vol.91 , pp. 949-956
    • Wang, Y.1    Chen, S.2    Yu, O.3
  • 122
    • 80052033347 scopus 로고    scopus 로고
    • Stepwise increase of resveratrol biosynthesis in yeast Saccharomyces cerevisiae by metabolic engineering
    • Wang Y, Halls C, Zhang J, Matsuno M, Zhang Y, Yu O (2011b) Stepwise increase of resveratrol biosynthesis in yeast Saccharomyces cerevisiae by metabolic engineering. Metab Eng 13: 455-463
    • (2011) Metab Eng , vol.13 , pp. 455-463
    • Wang, Y.1    Halls, C.2    Zhang, J.3    Matsuno, M.4    Zhang, Y.5    Yu, O.6
  • 123
    • 84855229099 scopus 로고    scopus 로고
    • Synthetic scaffolds increased resveratrol biosynthesis in engineered yeast cells
    • Wang Y, Yu O (2012) Synthetic scaffolds increased resveratrol biosynthesis in engineered yeast cells. J Biotechnol 157: 258-260
    • (2012) J Biotechnol , vol.157 , pp. 258-260
    • Wang, Y.1    Yu, O.2
  • 124
    • 3242737570 scopus 로고    scopus 로고
    • Exploring recombinant flavonoid biosynthesis in metabolically engineered Escherichia coli
    • Watts KT, Lee PC, Schmidt-Dannert C (2004) Exploring recombinant flavonoid biosynthesis in metabolically engineered Escherichia coli. ChemBioChem 5: 500-507
    • (2004) Chembiochem , vol.5 , pp. 500-507
    • Watts, K.T.1    Lee, P.C.2    Schmidt-Dannert, C.3
  • 125
    • 33645779318 scopus 로고    scopus 로고
    • Biosynthesis of plant-specific stilbene polyketides in metabolically engineered Escherichia coli
    • Watts KT, Lee PC, Schmidt-Dannert C (2006) Biosynthesis of plant-specific stilbene polyketides in metabolically engineered Escherichia coli. BMC Biotechnol 6: 22
    • (2006) BMC Biotechnol , vol.6 , pp. 22
    • Watts, K.T.1    Lee, P.C.2    Schmidt-Dannert, C.3
  • 127
    • 84883232076 scopus 로고    scopus 로고
    • Multivariate modular metabolic engineering of Escherichia coli to produce resveratrol from L-tyrosine
    • Wu J, Liu P, Fan Y, Bao H, Du G, Zhou J, Chen J (2013) Multivariate modular metabolic engineering of Escherichia coli to produce resveratrol from L-tyrosine. J Biotechnol 167: 404-411
    • (2013) J Biotechnol , vol.167 , pp. 404-411
    • Wu, J.1    Liu, P.2    Fan, Y.3    Bao, H.4    Du, G.5    Zhou, J.6    Chen, J.7
  • 128
  • 129
    • 22144478327 scopus 로고    scopus 로고
    • Metabolic engineering of anthocyanin biosynthesis in Escherichia coli
    • Yan Y, Chemler J, Huang L, Martens S, Koffas MAG (2005a) Metabolic engineering of anthocyanin biosynthesis in Escherichia coli. Appl Environ Microbiol 71: 3617-3623
    • (2005) Appl Environ Microbiol , vol.71 , pp. 3617-3623
    • Yan, Y.1    Chemler, J.2    Huang, L.3    Martens, S.4    Koffas, M.5
  • 130
    • 35748974224 scopus 로고    scopus 로고
    • Biosynthesis of 5-deoxyflavanones in microorganisms
    • Yan Y, Huang L, Koffas MAG (2007) Biosynthesis of 5-deoxyflavanones in microorganisms. Biotechnol J 2: 1250-1262
    • (2007) Biotechnol J , vol.2 , pp. 1250-1262
    • Yan, Y.1    Huang, L.2    Koffas, M.3
  • 131
    • 25144431998 scopus 로고    scopus 로고
    • Biosynthesis of natural flavanones in Saccharomyces cerevisiae
    • Yan Y, Kohli A, Koffas MAG (2005b) Biosynthesis of natural flavanones in Saccharomyces cerevisiae. Appl Environ Microbiol 71: 5610-5613
    • (2005) Appl Environ Microbiol , vol.71 , pp. 5610-5613
    • Yan, Y.1    Kohli, A.2    Koffas, M.3
  • 132
    • 42549160385 scopus 로고    scopus 로고
    • High-yield anthocyanin biosynthesis in engineered Escherichia coli
    • Yan Y, Li Z, Koffas MAG (2008) High-yield anthocyanin biosynthesis in engineered Escherichia coli. Biotechnol Bioeng 100: 126-140
    • (2008) Biotechnol Bioeng , vol.100 , pp. 126-140
    • Yan, Y.1    Li, Z.2    Koffas, M.3
  • 133
    • 31844438350 scopus 로고    scopus 로고
    • ABC transporters involved in the transport of plant secondary metabolites
    • Yazaki K (2006) ABC transporters involved in the transport of plant secondary metabolites. FEBS Lett 580: 1183-1191
    • (2006) FEBS Lett , vol.580 , pp. 1183-1191
    • Yazaki, K.1
  • 134
    • 84859083398 scopus 로고    scopus 로고
    • Type III polyketide synthases in natural product biosynthesis
    • Yu D, Xu F, Zeng J, Zhan J (2012) Type III polyketide synthases in natural product biosynthesis. IUBMB Life 64: 285-295
    • (2012) IUBMB Life , vol.64 , pp. 285-295
    • Yu, D.1    Xu, F.2    Zeng, J.3    Zhan, J.4
  • 135
    • 39749180988 scopus 로고    scopus 로고
    • Isolation and functional characterization of a/-eudesmol synthase, a new sesquiterpene synthase from Zingiber zerumbet Smith
    • Yu F, Harada H, Yamasaki K, Okamoto S, Hirase S, Tanaka Y, Misawa N, Utsumi R (2008a) Isolation and functional characterization of a/-eudesmol synthase, a new sesquiterpene synthase from Zingiber zerumbet Smith. FEBS Lett 582: 565-572
    • (2008) FEBS Lett , vol.582 , pp. 565-572
    • Yu, F.1    Harada, H.2    Yamasaki, K.3    Okamoto, S.4    Hirase, S.5    Tanaka, Y.6    Misawa, N.7    Utsumi, R.8
  • 136
    • 79953698422 scopus 로고    scopus 로고
    • Zingiber zerumbet CYP71BA1 catalyzes the conversion of a-humulene to 8-hydroxy-a-humulene in zerumbone biosynthesis
    • Yu F, Okamoto S, Harada H, Yamasaki K, Misawa N, Utsumi R (2011) Zingiber zerumbet CYP71BA1 catalyzes the conversion of a-humulene to 8-hydroxy-a-humulene in zerumbone biosynthesis. Cell Mol Life Sci 68: 1033-1040
    • (2011) Cell Mol Life Sci , vol.68 , pp. 1033-1040
    • Yu, F.1    Okamoto, S.2    Harada, H.3    Yamasaki, K.4    Misawa, N.5    Utsumi, R.6
  • 137
    • 42149123319 scopus 로고    scopus 로고
    • Molecular cloning and functional characterization of a-humulene synthase, a possible key enzyme of zerumbone biosynthesis in shampoo ginger (Zingiber zerumbet Smith)
    • Yu F, Okamoto S, Nakasone K, Adachi K, Matsuda S, Harada H, Misawa N, Utsumi R (2008b) Molecular cloning and functional characterization of a-humulene synthase, a possible key enzyme of zerumbone biosynthesis in shampoo ginger (Zingiber zerumbet Smith). Planta 227: 1291-1299
    • (2008) Planta , vol.227 , pp. 1291-1299
    • Yu, F.1    Okamoto, S.2    Nakasone, K.3    Adachi, K.4    Matsuda, S.5    Harada, H.6    Misawa, N.7    Utsumi, R.8
  • 138
    • 29544444196 scopus 로고    scopus 로고
    • Chromosomal promoter replacement of the isoprenoid pathway for enhancing carotenoid production in
    • Yuan LZ, Rouvière PE, LaRossa RA, Suh W (2006) Chromosomal promoter replacement of the isoprenoid pathway for enhancing carotenoid production in E. coli. Metab Eng 8: 79-90
    • (2006) E. Coli. Metab Eng , vol.8 , pp. 79-90
    • Yuan, L.Z.1    Rouvière, P.E.2    Larossa, R.A.3    Suh, W.4
  • 139
    • 84876676603 scopus 로고    scopus 로고
    • Engineering E. Coli for caffeic acid biosynthesis from renewable sugars
    • Zhang H, Stephanopoulos G (2013) Engineering E. coli for caffeic acid biosynthesis from renewable sugars. Appl Microbiol Biotechnol 97: 3333-3341
    • (2013) Appl Microbiol Biotechnol , vol.97 , pp. 3333-3341
    • Zhang, H.1    Stephanopoulos, G.2
  • 141
    • 84863116515 scopus 로고    scopus 로고
    • Modular pathway engineering of diterpenoid synthases and the mevalonic acid pathway for miltiradiene production
    • Zhou YJ, Gao W, Rong Q, Jin G, Chu H, Liu W, Yang W, Zhu Z, Li G, Zhu G, et al. (2012) Modular pathway engineering of diterpenoid synthases and the mevalonic acid pathway for miltiradiene production. J Am Chem Soc 134: 3234-3241
    • (2012) J am Chem Soc , vol.134 , pp. 3234-3241
    • Zhou, Y.J.1    Gao, W.2    Rong, Q.3    Jin, G.4    Chu, H.5    Liu, W.6    Yang, W.7    Zhu, Z.8    Li, G.9    Zhu, G.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.