Zingiber zerumbet CYP71BA1 catalyzes the conversion of α-humulene to 8-hydroxy-α-humulene in zerumbone biosynthesis

Cellular and Molecular Life Sciences

Volumn 68, Issue 6, 2011, Pages 1033-1040

  Yu, Fengnian ^a   Okamoto, Sho ^a   Harada, Hisashi ^b   Yamasaki, Kazuhisa ^a   Misawa, Norihiko ^b   Utsumi, Ryutaro ^a  

^a KINKI UNIVERSITY   (Japan)

^b KIRIN HOLDINGS CO LTD   (Japan)

Author keywords

8 hydroxy humulene; CYP71BA1; Metabolic engineering; Mevalonate pathway; P450; Zingiber zerumbet Smith

Indexed keywords

8 HYDROXY ALPHA HUMULENE; CELL PROTEIN; CYTOCHROME P450; CYTOCHROME P450 71BA1; HUMULENE; MEVALONIC ACID; PROTEIN ZSS1; SESQUITERPENE DERIVATIVE; UNCLASSIFIED DRUG; ZERUMBONE;

ARTICLE; BIOSYNTHESIS; CLONE; ESCHERICHIA COLI; GENE CLUSTER; GENE EXPRESSION; GINGER; NONHUMAN; NUCLEOTIDE SEQUENCE; PLANT DEVELOPMENT; RHIZOME; YEAST; ZINGIBER ZERUMBET;

BIOENGINEERING; CLONING, MOLECULAR; CLUSTER ANALYSIS; CYTOCHROME P-450 ENZYME SYSTEM; DNA PRIMERS; DNA, COMPLEMENTARY; ESCHERICHIA COLI; GINGER; MEVALONIC ACID; MOLECULAR STRUCTURE; PHYLOGENY; RHIZOME; SESQUITERPENES; SYNTHETIC BIOLOGY; YEASTS;

ESCHERICHIA COLI; ZINGIBER ZERUMBET;

EID: 79953698422     PISSN: 1420682X     EISSN: 14209071     Source Type: Journal    
DOI: 10.1007/s00018-010-0506-4     Document Type: Article

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