Balancing a heterologous mevalonate pathway for improved isoprenoid production in Escherichia coli

Metabolic Engineering

Volumn 9, Issue 2, 2007, Pages 193-207

  Pitera, Douglas J ^a   Paddon, Chris J ^b   Newman, Jack D ^b   Keasling, Jay D ^a,c,d  

^a University of California   (United States)

^b Amyris Biotechnologies   (United States)

^c University of California at Berkeley   (United States)

^d LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

Author keywords

E. coli; Isoprenoids; Mevalonate pathway; Pathway engineering; Toxicity

Indexed keywords

CELL CULTURE; DRUG PRODUCTS; ENZYMES; ESCHERICHIA COLI; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; METABOLITES; TOXICITY;

CARBON FLUX; ISOPRENOIDS; MEVALONATE PATHWAY; PATHWAY ENGINEERING;

BIOSYNTHESIS;

HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE; ISOPRENOID; MEVALONIC ACID;

ARTICLE; BIOSYNTHESIS; CONTROLLED STUDY; DRUG SYNTHESIS; ENZYME ACTIVITY; ESCHERICHIA COLI; GROWTH INHIBITION; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL;

ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; GENETIC ENHANCEMENT; MEVALONIC ACID; PROTEIN ENGINEERING; RECOMBINANT PROTEINS; SIGNAL TRANSDUCTION; TERPENES;

ESCHERICHIA COLI;

EID: 33847309176     PISSN: 10967176     EISSN: 10967184     Source Type: Journal    
DOI: 10.1016/j.ymben.2006.11.002     Document Type: Article

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