The flavonoid quercetin ameliorates Alzheimer's disease pathology and protects cognitive and emotional function in aged triple transgenic Alzheimer's disease model mice

Neuropharmacology

Volumn 93, Issue , 2015, Pages 134-145

  Sabogal Guáqueta, Angélica Maria ^a   Muñoz Manco, Juan Ignacio ^a   Ramírez Pineda, Jose R ^a   Lamprea Rodriguez, Marisol ^b   Osorio, Edison ^a   Cardona Gómez, Gloria Patricia ^a  

^a UNIVERSIDAD DE ANTIOQUIA   (Colombia)

^b UNIVERSIDAD NACIONAL DE COLOMBIA   (Colombia)

Author keywords

Alzheimer's disease; Cognitive function; Neuroprotection; Quercetin; Tauopathy; amyloidosis

Indexed keywords

AMYLOID BETA PROTEIN[1-40]; AMYLOID BETA PROTEIN[1-42]; AMYLOID PRECURSOR PROTEIN; BETA SECRETASE 1; QUERCETIN; AMYLOID BETA PROTEIN; ANTIOXIDANT; NERVE PROTEIN; PRESENILIN 1; TAU PROTEIN;

ALZHEIMER DISEASE; AMYGDALOID NUCLEUS; AMYLOIDOSIS; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASTROCYTOSIS; BRAIN REGION; CONTROLLED STUDY; DRUG EFFICACY; DRUG PROTEIN BINDING; DRUG RESPONSE; DRUG TARGETING; ELEVATED PLUS MAZE TEST; EMOTION; GLIOSIS; HIPPOCAMPUS; IN VIVO STUDY; LEARNING; MEMORY; MOUSE; MOUSE MODEL; NEUROPROTECTION; NONHUMAN; PROTEIN CLEAVAGE; PROTEIN DEGRADATION; PROTEIN PROTEIN INTERACTION; TASK PERFORMANCE; TAUOPATHY; TRANSGENIC MOUSE; AGING; ANIMAL; BRAIN; COGNITION DISORDERS; COMPLICATION; DISEASE MODEL; DRUG ADMINISTRATION; DRUG EFFECTS; GENETICS; GLIA; MAZE TEST; METABOLISM; MOOD DISORDERS; PATHOLOGY; REACTION TIME;

AGING; ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; ANTIOXIDANTS; BRAIN; COGNITION DISORDERS; DISEASE MODELS, ANIMAL; DRUG ADMINISTRATION SCHEDULE; GLIOSIS; MAZE LEARNING; MICE; MICE, TRANSGENIC; MOOD DISORDERS; NERVE TISSUE PROTEINS; NEUROGLIA; PRESENILIN-1; QUERCETIN; REACTION TIME; TAU PROTEINS;

EID: 84923115998     PISSN: 00283908     EISSN: 18737064     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2015.01.027     Document Type: Article

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