Potential neuroprotective flavonoid-based inhibitors of CDK5/p25 from Rhus parviflora

Bioorganic and Medicinal Chemistry Letters

Volumn 23, Issue 18, 2013, Pages 5150-5154

  Shrestha, Sabina ^a   Natarajan, Sathishkumar ^a   Park, Ji Hae ^a   Lee, Dae Young ^b   Cho, Jin Gyeong ^a   Kim, Geum Soog ^b   Jeon, Yong Jin ^c   Yeon, Seung Woo ^c   Yang, Deok Chun ^a   Baek, Nam In ^a  

^a Kyung Hee University   (South Korea)

^b Rural Development Administration   (South Korea)

^c ILDONG Pharmaceutical Co   (South Korea)

Author keywords

Alzheimer's disease; Aureusidin; CDK5 p25; Molecular docking; Rhus parviflora

Indexed keywords

ALSTERPAULLONE; BIFLAVONOID; FLAVONOID; FLAVONOID GLYCOSIDE; GLUCOPYRANOSIDE; NEUROPROTECTIVE AGENT; PROTEIN SERINE THREONINE KINASE INHIBITOR; ROSCOVITINE; STAUROSPORINE;

ARTICLE; BINDING AFFINITY; CRYSTAL STRUCTURE; DRUG CONFORMATION; GENETIC ALGORITHM; HYDROGEN BOND; IC 50; IN VITRO STUDY; MOLECULAR DOCKING; NEUROPROTECTION; NONHUMAN; POISON IVY; RHUS PARVIFLORA;

ANACARDIACEAE; RHUS PARVIFLORA;

ALZHEIMER'S DISEASE; AMJCTDBATIKENQ-NXIFTRESSA-N; AUREUSIDIN; CDK5/P25; KJIWCKSQHHNTTL-RDBLRTHZSA-N; LADPNODMUXOPRG-UHFFFAOYSA-N; MOLECULAR DOCKING; OVSQVDMCBVZWGM-BOYSSXRUSA-N; RGNXWPVNPFAADO-NSIKDUERSA-N; RHUS PARVIFLORA; WBEFUVAYFSOUEA-PQMHYQBVSA-N;

CYCLIN-DEPENDENT KINASE 5; FLAVONOIDS; HUMANS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; NERVE TISSUE PROTEINS; NEUROPROTECTIVE AGENTS; RHUS;

EID: 84882615679     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2013.07.020     Document Type: Article

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