-
1
-
-
0034829801
-
The molecular bases of Alzheimer's disease and other neurodegenerative disorders
-
Maccioni RB, Munoz JP, Barbeito L (2001) The molecular bases of Alzheimer's disease and other neurodegenerative disorders. Arch Med Res 32, 367-381.
-
(2001)
Arch Med Res
, vol.32
, pp. 367-381
-
-
Maccioni, R.B.1
Munoz, J.P.2
Barbeito, L.3
-
2
-
-
67651180986
-
The amyloid hypothesis for Alzheimer's disease: A critical reappraisal
-
Hardy J (2009) The amyloid hypothesis for Alzheimer's disease: A critical reappraisal. J Neurochem 110, 1129-1134.
-
(2009)
J Neurochem
, vol.110
, pp. 1129-1134
-
-
Hardy, J.1
-
3
-
-
36549083642
-
Neuroinflammation: Implications for the pathogenesis and molecular diagnosis of Alzheimer's disease
-
Rojo LE, Ferńandez JA,Maccioni AA, Jimenez JM, Maccioni RB (2008) Neuroinflammation: Implications for the pathogenesis and molecular diagnosis of Alzheimer's disease. Arch Med Res 39, 1-16.
-
(2008)
Arch Med Res
, vol.39
, pp. 1-16
-
-
Rojo, L.E.1
Ferńandez, J.A.2
Maccioni, A.A.3
Jimenez, J.M.4
Maccioni, R.B.5
-
5
-
-
47849121512
-
The damage signals hypothesis of Alzheimer's disease pathogenesis
-
Ferńandez JA, Rojo L, Kuljis RO, Maccioni RB (2008) The damage signals hypothesis of Alzheimer's disease pathogenesis. J Alzheimers Dis 14, 329-333.
-
(2008)
J Alzheimers Dis
, vol.14
, pp. 329-333
-
-
Ferńandez, J.A.1
Rojo, L.2
Kuljis, R.O.3
Maccioni, R.B.4
-
6
-
-
60349132064
-
The role of neuroimmunomodulation in Alzheimer's disease
-
Maccioni RB, Rojo LE, Ferńandez JA, Kuljis RO (2009) The role of neuroimmunomodulation in Alzheimer's disease. Ann N Y Acad Sci 1153, 240-246.
-
(2009)
Ann N y Acad Sci
, vol.1153
, pp. 240-246
-
-
Maccioni, R.B.1
Rojo, L.E.2
Ferńandez, J.A.3
Kuljis, R.O.4
-
7
-
-
0037336701
-
Interleukin-1 mediates pathological effects of microglia on tau phosphorylation and on synaptophysin synthesis in cortical neurons through a p38-MAPK pathway
-
LiY, Liu L, BargerSW, GriffinWS(2003) Interleukin-1 mediates pathological effects of microglia on tau phosphorylation and on synaptophysin synthesis in cortical neurons through a p38-MAPK pathway. J Neurosci 23, 1605-1611.
-
(2003)
J Neurosci
, vol.23
, pp. 1605-1611
-
-
Li, Y.1
Liu, L.2
Barger, S.W.3
Griffin, W.S.4
-
8
-
-
1642420308
-
Interleukin-6 induces Alzheimer-type phosphorylation of tau protein by deregulating the cdk5/p35 pathway
-
Quintanilla RA, Orellana DI, Gonźalez-Billault C, Maccioni RB (2004) Interleukin-6 induces Alzheimer-type phosphorylation of tau protein by deregulating the cdk5/p35 pathway. Exp Cell Res 295, 245-257.
-
(2004)
Exp Cell Res
, vol.295
, pp. 245-257
-
-
Quintanilla, R.A.1
Orellana, D.I.2
Gonźalez-Billault, C.3
Maccioni, R.B.4
-
9
-
-
4043058045
-
Astrocytic nitric oxide triggers tau hyperphosphorylation in hippocampal neurons
-
Saez TE, Pehar M,Vargas M, Barbeito L, MaccioniRB(2004) Astrocytic nitric oxide triggers tau hyperphosphorylation in hippocampal neurons. In Vivo 18, 275-280.
-
(2004)
Vivo
, vol.18
, pp. 275-280
-
-
Saez, T.E.1
Pehar, M.2
Vargas, M.3
Barbeito, L.4
Maccioni, R.B.5
-
10
-
-
68849123079
-
Accumulation of tau induced in neurites by microglial proinflammatory mediators
-
Gorlovoy P, Larionov S, Pham TT, Neumann H (2009) Accumulation of tau induced in neurites by microglial proinflammatory mediators. FASEB J 23, 2502-2513.
-
(2009)
FASEB J
, vol.23
, pp. 2502-2513
-
-
Gorlovoy, P.1
Larionov, S.2
Pham, T.T.3
Neumann, H.4
-
11
-
-
77957321869
-
Regulation of tau pathology by the microglial fractalkine receptor
-
Bhaskar K, Konerth M, Kokiko-Cochran ON, Cardona A, Ransohoff RM, Lamb BT (2010) Regulation of tau pathology by the microglial fractalkine receptor. Neuron 68, 19-31.
-
(2010)
Neuron
, vol.68
, pp. 19-31
-
-
Bhaskar, K.1
Konerth, M.2
Kokiko-Cochran, O.N.3
Cardona, A.4
Ransohoff, R.M.5
Lamb, B.T.6
-
12
-
-
80052714655
-
CX3CR1 modulates microglial activation and protects against plaque-independent cognitive deficits in a mouse model of Alzheimer's disease
-
Cho SH, Sun B, Zhou Y, Kauppinen TM, Halabisky B,Wes P, Ransohoff RM, Gan L (2011) CX3CR1 modulates microglial activation and protects against plaque-independent cognitive deficits in a mouse model of Alzheimer's disease. J Biol Chem 286, 32713-32722.
-
(2011)
J Biol Chem
, vol.286
, pp. 32713-32722
-
-
Cho, S.H.1
Sun, B.2
Zhou, Y.3
Kauppinen, T.M.4
Halabisky, B.5
Wes, P.6
Ransohoff, R.M.7
Gan, L.8
-
13
-
-
80155161291
-
Fulvic acid inhibits aggregation and promotes disassembly of tau fibrils associated with Alzheimer's disease
-
Cornejo A, Jim'enez JM, Caballero L, Melo F, Maccioni RB (2011) Fulvic acid inhibits aggregation and promotes disassembly of tau fibrils associated with Alzheimer's disease. J Alzheimers Dis 27, 143-153.
-
(2011)
J Alzheimers Dis
, vol.27
, pp. 143-153
-
-
Cornejo, A.1
Jim'Enez, J.M.2
Caballero, L.3
Melo, F.4
Maccioni, R.B.5
-
14
-
-
84858146982
-
Molecules of the quinoline family block tau self-aggregation: Implications towards therapeutic approach for Alzheimer's disease
-
Navarrete LP, Guzm'an L, San Mart'in A, Astudillo-Saavedra L, Maccioni RB (2012) Molecules of the quinoline family block tau self-aggregation: Implications towards therapeutic approach for Alzheimer's disease. J Alzheimers Dis 29, 79-88.
-
(2012)
J Alzheimers Dis
, vol.29
, pp. 79-88
-
-
Navarrete, L.P.1
Guzm'An, L.2
San Mart'In, A.3
Astudillo-Saavedra, L.4
Maccioni, R.B.5
-
15
-
-
0034705192
-
In vitro polymerization of tau protein monitored by laser light scattering: Method and application to the study of FTDP-17 mutants
-
Gamblin TC, King ME, Dawson H, Vitek MP, Kuret J, Berry RW, Binder LI (2000) In vitro polymerization of tau protein monitored by laser light scattering: Method and application to the study of FTDP-17 mutants. Biochemistry 39, 6136-6144.
-
(2000)
Biochemistry
, vol.39
, pp. 6136-6144
-
-
Gamblin, T.C.1
King, M.E.2
Dawson, H.3
Vitek, M.P.4
Kuret, J.5
Berry, R.W.6
Binder, L.I.7
-
16
-
-
43249092898
-
Preparation and coculture of neurons and glial cells
-
Unit 2.7
-
Viviani B (2006) Preparation and coculture of neurons and glial cells. Curr Protoc Cell Biol Chapter 2, Unit 2.7.
-
(2006)
Curr Protoc Cell Biol Chapter 2
-
-
Viviani, B.1
-
17
-
-
0035298135
-
ACdk5-p35 stable complex is involved in the beta-amyloid-induced deregulation of Cdk5 activity in hippocampal neurons
-
Alvarez A,Munoz JP,MaccioniRB(2001)ACdk5-p35 stable complex is involved in the beta-amyloid-induced deregulation of Cdk5 activity in hippocampal neurons. Exp Cell Res 264, 266-274.
-
(2001)
Exp Cell Res
, vol.264
, pp. 266-274
-
-
Alvarez, A.1
Munoz, J.P.2
Maccioni, R.B.3
-
18
-
-
0035709008
-
A rapid, simple spectrophotometric method for simultaneous detection of nitrate and nitrite
-
Miranda KM, Espey MG, Wink DA (2001) A rapid, simple spectrophotometric method for simultaneous detection of nitrate and nitrite. Nitric Oxide 5, 62-71.
-
(2001)
Nitric Oxide
, vol.5
, pp. 62-71
-
-
Miranda, K.M.1
Espey, M.G.2
Wink, D.A.3
-
19
-
-
22844445324
-
Purification of recombinant tau protein and preparation of Alzheimer-paired helical filaments in vitro
-
Barghorn S, Biernat J, Mandelkow E (2007) Purification of recombinant tau protein and preparation of Alzheimer-paired helical filaments in vitro. Methods Mol Biol 299, 35-51.
-
(2007)
Methods Mol Biol
, vol.299
, pp. 35-51
-
-
Barghorn, S.1
Biernat, J.2
Mandelkow, E.3
-
20
-
-
77953499350
-
The revitalized tau hypothesis on Alzheimer's disease
-
Maccioni RB, Faŕias G, Morales I, Navarrete L (2010) The revitalized tau hypothesis on Alzheimer's disease. Arch Med Res 41, 226-231.
-
(2010)
Arch Med Res
, vol.41
, pp. 226-231
-
-
Maccioni, R.B.1
Faŕias, G.2
Morales, I.3
Navarrete, L.4
-
21
-
-
76949087724
-
Neuroimmunomodulation in the pathogenesis of Alzheimer's disease
-
Morales I, Faŕias G, Maccioni RB (2010) Neuroimmunomodulation in the pathogenesis of Alzheimer's disease. Neuroimmunomodulation 17, 202-204.
-
(2010)
Neuroimmunomodulation
, vol.17
, pp. 202-204
-
-
Morales, I.1
Faŕias, G.2
Maccioni, R.B.3
-
22
-
-
55249086251
-
Hyperphosphorylation of microtubule-associated protein tau: A promising therapeutic target for Alzheimer disease
-
Gong CX, Iqbal K (2008) Hyperphosphorylation of microtubule-associated protein tau: A promising therapeutic target for Alzheimer disease. Curr Med Chem 15, 2321-2328.
-
(2008)
Curr Med Chem
, vol.15
, pp. 2321-2328
-
-
Gong, C.X.1
Iqbal, K.2
-
23
-
-
34548036227
-
Tau-mediated neurodegeneration in Alzheimer's disease and related disorders
-
Ballatore C, Lee VM, Trojanowski JQ (2007) Tau-mediated neurodegeneration in Alzheimer's disease and related disorders. Nat Rev Neurosci 8, 663-672.
-
(2007)
Nat Rev Neurosci
, vol.8
, pp. 663-672
-
-
Ballatore, C.1
Lee, V.M.2
Trojanowski, J.Q.3
-
24
-
-
84855813109
-
Activated microglia proliferate at neurites of mutant huntingtinexpressing neurons
-
Kraft AD, Kaltenbach LS, Lo DC, Harry GJ (2012) Activated microglia proliferate at neurites of mutant huntingtinexpressing neurons. Neurobiol Aging 33, 621.e17-33.
-
(2012)
Neurobiol Aging
, vol.33
-
-
Kraft, A.D.1
Kaltenbach, L.S.2
Lo, D.C.3
Harry, G.J.4
-
25
-
-
79951948479
-
Alpha-synuclein release by neurons activates the inflammatory response in a microglial cell line
-
Alvarez-Erviti L, Couch Y, Richardson J, Cooper JM, Wood MJ (2011) Alpha-synuclein release by neurons activates the inflammatory response in a microglial cell line. Neurosci Res 69, 337-342.
-
(2011)
Neurosci Res
, vol.69
, pp. 337-342
-
-
Alvarez-Erviti, L.1
Couch, Y.2
Richardson, J.3
Cooper, J.M.4
Wood, M.J.5
-
26
-
-
84864389497
-
Amyloid- oligomers stimulate microglia through a tyrosine kinase dependent mechanism
-
Dhawan G, Floden AM, Combs CK (2012) Amyloid- oligomers stimulate microglia through a tyrosine kinase dependent mechanism. Neurobiol Aging 33, 2247-2261.
-
(2012)
Neurobiol Aging
, vol.33
, pp. 2247-2261
-
-
Dhawan, G.1
Floden, A.M.2
Combs, C.K.3
-
27
-
-
78649503285
-
Preparation and characterization of neurotoxic tau oligomers
-
Lasagna-Reeves CA, Castillo-Carranza DL, Guerrero-Munoz MJ, Jackson GR, Kayed R (2010) Preparation and characterization of neurotoxic tau oligomers. Biochemistry 49, 10039-10041.
-
(2010)
Biochemistry
, vol.49
, pp. 10039-10041
-
-
Lasagna-Reeves, C.A.1
Castillo-Carranza, D.L.2
Guerrero-Munoz, M.J.3
Jackson, G.R.4
Kayed, R.5
-
28
-
-
80051517143
-
Tau oligomers as potential targets for immunotherapy for Alzheimer's disease and tauopathies
-
Lasagna-Reeves CA, Castillo-Carranza DL, Jackson GR, Kayed R (2011) Tau oligomers as potential targets for immunotherapy for Alzheimer's disease and tauopathies. Curr Alzheimer Res 8, 659-665.
-
(2011)
Curr Alzheimer Res
, vol.8
, pp. 659-665
-
-
Lasagna-Reeves, C.A.1
Castillo-Carranza, D.L.2
Jackson, G.R.3
Kayed, R.4
-
29
-
-
79957913270
-
Tau oligomers impair memory and induce synaptic and mitochondrial dysfunction in wild-type mice
-
Kayed R (2011) Tau oligomers impair memory and induce synaptic and mitochondrial dysfunction in wild-type mice. Mol Neurodegener 6, 39.
-
(2011)
Mol Neurodegener
, vol.6
, pp. 39
-
-
Kayed, R.1
-
30
-
-
84858965241
-
Identification of oligomers at early stages of tau aggregation in Alzheimer's disease
-
Lasagna-Reeves CA, Castillo-Carranza DL, Sengupta U, Sarmiento J, Troncoso J, Jackson GR, Kayed R (2012) Identification of oligomers at early stages of tau aggregation in Alzheimer's disease. FASEB J 26, 1946-1959.
-
(2012)
FASEB J
, vol.26
, pp. 1946-1959
-
-
Lasagna-Reeves, C.A.1
Castillo-Carranza, D.L.2
Sengupta, U.3
Sarmiento, J.4
Troncoso, J.5
Jackson, G.R.6
Kayed, R.7
-
31
-
-
84860215480
-
Correlation of Alzheimer disease neuropathologic changes with cognitive status: A review of the literature
-
Nelson PT, Alafuzoff I, Bigio EH, Bouras C, Braak H, Cairns NJ, Castellani RJ, Crain BJ, Davies P, Del Tredici K, Duyckaerts C, Frosch MP, Haroutunian V, Hof PR, Hulette CM, Hyman BT, Iwatsubo T, Jellinger KA, Jicha GA, Kovari E, Kukull WA, Leverenz JB, Love S, Mackenzie IR, Mann DM, Masliah E, McKee AC, Montine TJ, Morris JC, Schneider JA, Sonnen JA, Thal DR, Trojanowski JQ, Troncoso JC, Wisniewski T, Woltjer RL, Beach TG (2012) Correlation of Alzheimer disease neuropathologic changes with cognitive status: A review of the literature. J Neuropathol Exp Neurol 71, 362-381.
-
(2012)
J Neuropathol Exp Neurol
, vol.71
, pp. 362-381
-
-
Nelson, P.T.1
Alafuzoff, I.2
Bigio, E.H.3
Bouras, C.4
Braak, H.5
Cairns, N.J.6
Castellani, R.J.7
Crain, B.J.8
Davies, P.9
Del Tredici, K.10
Duyckaerts, C.11
Frosch, M.P.12
Haroutunian, V.13
Hof, P.R.14
Hulette, C.M.15
Hyman, B.T.16
Iwatsubo, T.17
Jellinger, K.A.18
Jicha, G.A.19
Kovari, E.20
Kukull, W.A.21
Leverenz, J.B.22
Love, S.23
Mackenzie, I.R.24
Mann, D.M.25
Masliah, E.26
McKee, A.C.27
Montine, T.J.28
Morris, J.C.29
Schneider, J.A.30
Sonnen, J.A.31
Thal, D.R.32
Trojanowski, J.Q.33
Troncoso, J.C.34
Wisniewski, T.35
Woltjer, R.L.36
Beach, T.G.37
more..
-
32
-
-
64549107543
-
Human misfolded truncated tau protein promotes activation of microglia and leukocyte infiltration in the transgenic rat model of tauopathy
-
Zilka N, Stozicka Z, Kovac A, Pilipcinec E, Bugos O, Novak M (2009) Human misfolded truncated tau protein promotes activation of microglia and leukocyte infiltration in the transgenic rat model of tauopathy. J Neuroimmunol 209, 16-25.
-
(2009)
J Neuroimmunol
, vol.209
, pp. 16-25
-
-
Zilka, N.1
Stozicka, Z.2
Kovac, A.3
Pilipcinec, E.4
Bugos, O.5
Novak, M.6
-
33
-
-
80052686057
-
Misfolded truncated protein induces innate immune response via MAPK pathway
-
Kovac A, Zilka N, Kazmerova Z, Cente M, Zilkova M, NovakM(2011) Misfolded truncated protein induces innate immune response via MAPK pathway. J Immunol 187, 2732- 2739.
-
(2011)
J Immunol
, vol.187
, pp. 2732-2739
-
-
Kovac, A.1
Zilka, N.2
Kazmerova, Z.3
Cente, M.4
Zilkova, M.5
Novak, M.6
-
34
-
-
84855857748
-
Immunopathogenesis of neurodegenerative diseases: Current therapeutic models of neuroprotection with special reference to natural products
-
Magrone T, Marzulli G, Jirillo E (2012) Immunopathogenesis of neurodegenerative diseases: Current therapeutic models of neuroprotection with special reference to natural products. Curr Pharm Des 18, 34-42.
-
(2012)
Curr Pharm des
, vol.18
, pp. 34-42
-
-
Magrone, T.1
Marzulli, G.2
Jirillo, E.3
-
35
-
-
79959676154
-
Microglial phagocytosis induced by fibrillar beta-amyloid is attenuated by oligomeric beta amyloid: Implications for Alzheimer's disease
-
Pan XD, Zhu YG, Lin N, Zhang J, Ye QY, Huang HP, Chen XC (2011) Microglial phagocytosis induced by fibrillar beta-amyloid is attenuated by oligomeric beta amyloid: Implications for Alzheimer's disease. Mol Neurodegener 6, 45.
-
(2011)
Mol Neurodegener
, vol.6
, pp. 45
-
-
Pan, X.D.1
Zhu, Y.G.2
Lin, N.3
Zhang, J.4
Ye, Q.Y.5
Huang, H.P.6
Chen, X.C.7
|