메뉴 건너뛰기




Volumn 387, Issue 10, 2014, Pages 921-933

Quercetin mitigates Adriamycin-induced anxiety- and depression-like behaviors, immune dysfunction, and brain oxidative stress in rats

Author keywords

Adriamycin; Behavior; Immunity; Oxidative stress; Quercetin

Indexed keywords

ANTINEOPLASTIC ANTIBIOTIC; ANTIOXIDANT; DOXORUBICIN; QUERCETIN;

EID: 84930901430     PISSN: 00281298     EISSN: 14321912     Source Type: Journal    
DOI: 10.1007/s00210-014-1008-y     Document Type: Article
Times cited : (87)

References (82)
  • 1
    • 33847195328 scopus 로고    scopus 로고
    • Candidate mechanisms for chemotherapy-induced cognitive changes
    • 17318212 1:CAS:528:DC%2BD2sXitVGrsbw%3D 3329763 10.1038/nrc2073 PMID: 17318212
    • Ahles TA, Saykin AJ (2007) Candidate mechanisms for chemotherapy-induced cognitive changes. Nat Rev Cancer 7:192-201, PMID: 17318212
    • (2007) Nat Rev Cancer , vol.7 , pp. 192-201
    • Ahles, T.A.1    Saykin, A.J.2
  • 2
    • 0037276434 scopus 로고    scopus 로고
    • In vitro immunomodulatory activity of flavonoid glycosides from Urtica dioica L
    • 12557244 1:CAS:528:DC%2BD3sXhs12htro%3D 10.1002/ptr.1068 PMID: 12557244
    • Akbay P, Basaran AA, Undeger U, Basaran N (2003) In vitro immunomodulatory activity of flavonoid glycosides from Urtica dioica L. Phytother Res 17:34-37, PMID: 12557244
    • (2003) Phytother Res , vol.17 , pp. 34-37
    • Akbay, P.1    Basaran, A.A.2    Undeger, U.3    Basaran, N.4
  • 3
    • 1642494640 scopus 로고    scopus 로고
    • Antidepressant activity of quercetin, a bioflavonoid, in streptozotocin-induced diabetic mice
    • 14977450 1:CAS:528:DC%2BD2cXmvVCksQ%3D%3D 10.1089/109662003772519976 PMID: 14977450
    • Anjaneyulu M, Chopra K, Kaur I (2003) Antidepressant activity of quercetin, a bioflavonoid, in streptozotocin-induced diabetic mice. J Med Food 6(4):391-395, PMID: 14977450
    • (2003) J Med Food , vol.6 , Issue.4 , pp. 391-395
    • Anjaneyulu, M.1    Chopra, K.2    Kaur, I.3
  • 5
    • 0031418498 scopus 로고    scopus 로고
    • Neurodegenerative disorders in humans: The role of glutathione in oxidative stress-mediated neuronal death
    • 9495562 1:CAS:528:DyaK2sXnvFKjs7c%3D 10.1016/S0165-0173(97)00045-3 PMID: 9495562
    • Bains JS, Shaw CA (1997) Neurodegenerative disorders in humans: the role of glutathione in oxidative stress-mediated neuronal death. Brain Res Rev 25:335-358, PMID: 9495562
    • (1997) Brain Res Rev , vol.25 , pp. 335-358
    • Bains, J.S.1    Shaw, C.A.2
  • 6
    • 70449529633 scopus 로고    scopus 로고
    • The blood-brain barrier and immune function and dysfunction
    • 19664708 1:CAS:528:DC%2BD1MXhsVGms7vK 10.1016/j.nbd.2009.07.031 PMID: 19664708
    • Banks WA, Erickson MA (2010) The blood-brain barrier and immune function and dysfunction. Neurobiol Dis 37:26-32, PMID: 19664708
    • (2010) Neurobiol Dis , vol.37 , pp. 26-32
    • Banks, W.A.1    Erickson, M.A.2
  • 7
    • 31444441701 scopus 로고    scopus 로고
    • New approaches to antidepressant drug discovery: Beyond monoamines
    • 16429123 1:CAS:528:DC%2BD28XlvV2qug%3D%3D 10.1038/nrn1846 PMID: 16429123
    • Berton O, Nestler EJ (2006) New approaches to antidepressant drug discovery: beyond monoamines. Nat Rev Neurosci 7:137-151, PMID: 16429123
    • (2006) Nat Rev Neurosci , vol.7 , pp. 137-151
    • Berton, O.1    Nestler, E.J.2
  • 8
    • 77955056458 scopus 로고    scopus 로고
    • Reversal by quercetin of corticotrophin releasing factor induced anxiety- and depression-like effect in mice
    • 20447436 1:CAS:528:DC%2BC3cXpt1Krtrk%3D 10.1016/j.pnpbp.2010.04.025 PMID: 20447436
    • Bhutada P, Mundhada Y, Bansod K, Ubgade A, Quazi M, Umathe S, Mundhada D (2010) Reversal by quercetin of corticotrophin releasing factor induced anxiety- and depression-like effect in mice. Prog Neuropsychopharmacol Biol Psychiatry 34(6):955-960, PMID: 20447436
    • (2010) Prog Neuropsychopharmacol Biol Psychiatry , vol.34 , Issue.6 , pp. 955-960
    • Bhutada, P.1    Mundhada, Y.2    Bansod, K.3    Ubgade, A.4    Quazi, M.5    Umathe, S.6    Mundhada, D.7
  • 9
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • 942051 1:CAS:528:DyaE28XksVehtrY%3D 10.1016/0003-2697(76)90527-3 PMID: 942051
    • Bradford MM (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72:248-254, PMID: 942051
    • (1976) Anal Biochem , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 10
    • 33947606762 scopus 로고    scopus 로고
    • Interaction of flavonoids with red blood cell membrane lipids and proteins: Antioxidant and antihemolytic effects
    • 17239435 1:CAS:528:DC%2BD2sXjslehtr0%3D 10.1016/j.ijbiomac.2006.12.003 PMID: 17239435
    • Chaudhuri S, Banerjee A, Basu K, Sengupta B, Sengupta PK (2007) Interaction of flavonoids with red blood cell membrane lipids and proteins: antioxidant and antihemolytic effects. Int J Biol Macromol 41:42-48, PMID: 17239435
    • (2007) Int J Biol Macromol , vol.41 , pp. 42-48
    • Chaudhuri, S.1    Banerjee, A.2    Basu, K.3    Sengupta, B.4    Sengupta, P.K.5
  • 11
    • 34548486746 scopus 로고    scopus 로고
    • Immunomodulatory activities of common vegetables and spices of Umbelliferae and its related coumarins and flavonoids
    • 10.1016/j.foodchem.2007.07.005 1:CAS:528:DC%2BD2sXhtVerurvK 10.1016/j.foodchem.2007.07.005
    • Cherng JM, Chiang W, Chiang LC (2008) Immunomodulatory activities of common vegetables and spices of Umbelliferae and its related coumarins and flavonoids. Food Chem 106:944-950. doi: 10.1016/j.foodchem.2007.07.005
    • (2008) Food Chem , vol.106 , pp. 944-950
    • Cherng, J.M.1    Chiang, W.2    Chiang, L.C.3
  • 12
    • 33746533375 scopus 로고    scopus 로고
    • Protective effect of quercetin, a natural flavonoid against neuronal damage after transient global cerebral ischemia
    • 10.1016/j.neulet.2006.06.010 16806698 1:CAS:528:DC%2BD28Xns12ksLc%3D 10.1016/j.neulet.2006.06.010
    • Cho JY, Kim IS, Jang YH, Kim AR, Lee SY (2006) Protective effect of quercetin, a natural flavonoid against neuronal damage after transient global cerebral ischemia. Neurosci Lett 404:330-335. doi: 10.1016/j.neulet.2006.06.010
    • (2006) Neurosci Lett , vol.404 , pp. 330-335
    • Cho, J.Y.1    Kim, I.S.2    Jang, Y.H.3    Kim, A.R.4    Lee, S.Y.5
  • 13
    • 0037281331 scopus 로고    scopus 로고
    • Quercetin suppresses proinflammatory cytokines production through MAP kinases and NF-κB pathway in lipopolysaccharide-stimulated macrophage
    • 12619901 1:CAS:528:DC%2BD38XpsFyjtLg%3D 10.1023/A:1021624520740 PMID:12619901
    • Cho SY, Park SJ, Kwon MJ, Jeong TS, Bok SH, Choi WY, Jeong WI, Ryu SY, Do SH, Lee CS, Song JC, Jeong KS (2003) Quercetin suppresses proinflammatory cytokines production through MAP kinases and NF-κB pathway in lipopolysaccharide-stimulated macrophage. Mol Cell Biochem 243:153-160, PMID:12619901
    • (2003) Mol Cell Biochem , vol.243 , pp. 153-160
    • Cho, S.Y.1    Park, S.J.2    Kwon, M.J.3    Jeong, T.S.4    Bok, S.H.5    Choi, W.Y.6    Jeong, W.I.7    Ryu, S.Y.8    Do, S.H.9    Lee, C.S.10    Song, J.C.11    Jeong, K.S.12
  • 14
    • 84855658175 scopus 로고    scopus 로고
    • Effect of quercetin on learning and memory performance in ICR mice under neurotoxic trimethyltin exposure
    • 10.1016/j.foodchem.2011.11.089 1:CAS:528:DC%2BC3MXhs1KrurvJ 10.1016/j.foodchem.2011.11.089
    • Choi GN, Kima JH, Kwak JH, Jeong CH, Jeong HR, Lee U, Heo HJ (2012) Effect of quercetin on learning and memory performance in ICR mice under neurotoxic trimethyltin exposure. Food Chem 132:1019-1024. doi: 10.1016/j.foodchem.2011.11.089
    • (2012) Food Chem , vol.132 , pp. 1019-1024
    • Choi, G.N.1    Kima, J.H.2    Kwak, J.H.3    Jeong, C.H.4    Jeong, H.R.5    Lee, U.6    Heo, H.J.7
  • 15
    • 0034903806 scopus 로고    scopus 로고
    • Behavioral and biochemical effects of glutathione depletion in the rat brain
    • 11489339 1:CAS:528:DC%2BD3MXls1eiurY%3D 10.1016/S0361-9230(01)00484-1 PMID:11489339
    • Cruz-Aguado R, Almaguer-Melian W, Díaz CM, Lorigados L, Bergado J (2001) Behavioral and biochemical effects of glutathione depletion in the rat brain. Brain Res Bull 55(3):327-333, PMID:11489339
    • (2001) Brain Res Bull , vol.55 , Issue.3 , pp. 327-333
    • Cruz-Aguado, R.1    Almaguer-Melian, W.2    Díaz, C.M.3    Lorigados, L.4    Bergado, J.5
  • 16
    • 0036570222 scopus 로고    scopus 로고
    • Assessing antidepressant activity in rodents: Recent developments and future needs
    • 12008002 1:CAS:528:DC%2BD38XjsVWjsbo%3D 10.1016/S0165-6147(02)02017-5 PMID:12008002
    • Cryan JF, Markou A, Lucki I (2002) Assessing antidepressant activity in rodents: recent developments and future needs. Trends Pharmacol Sci 23:238-345, PMID:12008002
    • (2002) Trends Pharmacol Sci , vol.23 , pp. 238-345
    • Cryan, J.F.1    Markou, A.2    Lucki, I.3
  • 17
    • 2142797481 scopus 로고    scopus 로고
    • Sequence specificity of adriamycin-DNA adducts in human tumor cells
    • 12883039 1:CAS:528:DC%2BD3sXmsFGktrw%3D PMID:12883039
    • Cutts SM, Swift LP, Rephaeli A, Nudelman A, Phillips DR (2003) Sequence specificity of adriamycin-DNA adducts in human tumor cells. Mol Cancer Ther 2:661-670, PMID:12883039
    • (2003) Mol Cancer Ther , vol.2 , pp. 661-670
    • Cutts, S.M.1    Swift, L.P.2    Rephaeli, A.3    Nudelman, A.4    Phillips, D.R.5
  • 18
    • 23944478990 scopus 로고    scopus 로고
    • A review of recent studies on malondialdehyde as toxic molecule and biological marker of oxidative stress
    • 16054557 10.1016/j.numecd.2005.05.003 PMID:16054557
    • Del Rio D, Stewart AJ, Pellegrini N (2005) A review of recent studies on malondialdehyde as toxic molecule and biological marker of oxidative stress. Nutr Metab Cardiovasc Dis 15:316-328, PMID:16054557
    • (2005) Nutr Metab Cardiovasc Dis , vol.15 , pp. 316-328
    • Del Rio, D.1    Stewart, A.J.2    Pellegrini, N.3
  • 19
    • 12244283706 scopus 로고    scopus 로고
    • Neuroprotective effects of antioxidative flavonoids, quercetin, (+)-dihydroquercetin and quercetin 3-methyl ether, isolated from Opuntia ficus-indica var. Saboten
    • 12591129 1:CAS:528:DC%2BD3sXht1Kms74%3D 10.1016/S0006-8993(02)04150-1 PMID:12591129
    • Dok-Go H, Lee KH, Kim HJ, Lee EH, Lee J, Song YS (2003) Neuroprotective effects of antioxidative flavonoids, quercetin, (+)-dihydroquercetin and quercetin 3-methyl ether, isolated from Opuntia ficus-indica var. saboten. Brain Res 965:130-136, PMID:12591129
    • (2003) Brain Res , vol.965 , pp. 130-136
    • Dok-Go, H.1    Lee, K.H.2    Kim, H.J.3    Lee, E.H.4    Lee, J.5    Song, Y.S.6
  • 20
    • 0025142672 scopus 로고
    • Malondialdehyde determination as index of lipid peroxidation
    • 2233309 1:CAS:528:DyaK3MXksVGhtLo%3D 10.1016/0076-6879(90)86135-I PMID:2233309
    • Draper HH, Hadley M (1990) Malondialdehyde determination as index of lipid peroxidation. Meth Enzymol 186:421-431, PMID:2233309
    • (1990) Meth Enzymol , vol.186 , pp. 421-431
    • Draper, H.H.1    Hadley, M.2
  • 21
    • 77956302299 scopus 로고    scopus 로고
    • Neurobehavioral manifestations of developmental impairment of the brain
    • 21217874 2984125 10.2478/v10102-010-0012-4 PMID:21217874
    • Dubovický M (2010) Neurobehavioral manifestations of developmental impairment of the brain. Interdiscip Toxicol 3(2):59-67, PMID:21217874
    • (2010) Interdiscip Toxicol , vol.3 , Issue.2 , pp. 59-67
    • Dubovický, M.1
  • 22
    • 3042934967 scopus 로고
    • Tissue sulfhydryl groups
    • 13650640 1:CAS:528:DyaG1MXotl2ksA%3D%3D 10.1016/0003-9861(59)90090-6 PMID:13650640
    • Ellman GL (1959) Tissue sulfhydryl groups. Arch Biochem Biophys 82(486):70-77, PMID:13650640
    • (1959) Arch Biochem Biophys , vol.82 , Issue.486 , pp. 70-77
    • Ellman, G.L.1
  • 23
    • 22244467104 scopus 로고    scopus 로고
    • Prenatal stress produces more behavioral alterations than maternal separation in the elevated plus-maze and in the elevated T-maze
    • 15941599 10.1016/j.bbr.2005.04.003 PMID:15941599
    • Estanislau C, Morato S (2005) Prenatal stress produces more behavioral alterations than maternal separation in the elevated plus-maze and in the elevated T-maze. Behav Brain Res 163:70-77, PMID:15941599
    • (2005) Behav Brain Res , vol.163 , pp. 70-77
    • Estanislau, C.1    Morato, S.2
  • 24
    • 71549141319 scopus 로고    scopus 로고
    • UVA and UVB radiation-induced oxidation products of quercetin
    • 1:CAS:528:DC%2BD1MXhtlyrtbjJ
    • Fahlman BM, Krol ES (2009) UVA and UVB radiation-induced oxidation products of quercetin. Photochem Photobiol B 97:123-131, PMID:19782575
    • (2009) Photochem Photobiol B , vol.97 , pp. 123-131
    • Fahlman, B.M.1    Krol, E.S.2
  • 25
    • 0021797854 scopus 로고
    • Hematological toxicity: Experience with anthracyclines and anthracenes
    • 3857185 1:CAS:528:DyaL2MXlsFentrg%3D PMID:3857185
    • Falkson G, Klein B, Falkson H (1985) Hematological toxicity: experience with anthracyclines and anthracenes. Exp Hematol 13(Suppl 16):64-71, PMID:3857185
    • (1985) Exp Hematol , vol.13 , pp. 64-71
    • Falkson, G.1    Klein, B.2    Falkson, H.3
  • 26
    • 45749089003 scopus 로고    scopus 로고
    • Quercetin: Further investigation of its antinociceptive properties and mechanisms of action
    • 10.1007/s12272-001-1217-2 18563352 10.1007/s12272-001-1217-2
    • Filho AW, Filho VC, Olinger L, de Souza MM (2008) Quercetin: further investigation of its antinociceptive properties and mechanisms of action. Arch Pharm Res 31(6):713-721. doi: 10.1007/s12272-001-1217-2
    • (2008) Arch Pharm Res , vol.31 , Issue.6 , pp. 713-721
    • Filho, A.W.1    Filho, V.C.2    Olinger, L.3    De Souza, M.M.4
  • 27
    • 0013633948 scopus 로고
    • Immunologic effects of cancer chemotherapy
    • G. Powis M. Hacker (eds) Pergamon Press New York
    • Grant LD, Kaesberg PR, Ershler WB (1991) Immunologic effects of cancer chemotherapy. In: Powis G, Hacker MP (eds) The toxicity of anticancer drugs. Pergamon Press, New York, pp 167-197
    • (1991) The Toxicity of Anticancer Drugs , pp. 167-197
    • Grant, L.D.1    Kaesberg, P.R.2    Ershler, W.B.3
  • 28
    • 0016811010 scopus 로고
    • Disposition of quercetin in man after single oral and intravenous doses
    • 1233267 1:CAS:528:DyaE28XhtFGlsrs%3D 10.1007/BF00614022 PMID: 1233267
    • Gugler R, Loschik M, Dengler MJ (1975) Disposition of quercetin in man after single oral and intravenous doses. Eur J Clin Pharmacol 9:229-235, PMID: 1233267
    • (1975) Eur J Clin Pharmacol , vol.9 , pp. 229-235
    • Gugler, R.1    Loschik, M.2    Dengler, M.J.3
  • 29
    • 0016275313 scopus 로고
    • Glutathione S-transferase, the first enzymatic step in mercapturic acid formation
    • 4436300 1:CAS:528:DyaE2MXltlahtg%3D%3D PMID:4436300
    • Habig WH, Pabst MJ, Jakoby WB (1974) Glutathione S-transferase, the first enzymatic step in mercapturic acid formation. J Biol Chem 249:7130-7139, PMID:4436300
    • (1974) J Biol Chem , vol.249 , pp. 7130-7139
    • Habig, W.H.1    Pabst, M.J.2    Jakoby, W.B.3
  • 30
    • 70349483998 scopus 로고    scopus 로고
    • Flavonoid quercetin protects against swimming stress-induced changes in oxidative biomarkers in the hypothalamus of rats
    • 19744476 1:CAS:528:DC%2BD1MXht1Wrtr3F 10.1016/j.ejphar.2009.08.030 PMID:19744476
    • Haleagrahara N, Radhakrishnan A, Lee N, Kumar P (2009) Flavonoid quercetin protects against swimming stress-induced changes in oxidative biomarkers in the hypothalamus of rats. Eur J Pharmacol 621:46-52, PMID:19744476
    • (2009) Eur J Pharmacol , vol.621 , pp. 46-52
    • Haleagrahara, N.1    Radhakrishnan, A.2    Lee, N.3    Kumar, P.4
  • 31
    • 79960461573 scopus 로고    scopus 로고
    • Neuroprotective effect of bioflavonoid quercetin in 6-hydroxydopamine-induced oxidative stress biomarkers in the rat striatum
    • 21704673 1:CAS:528:DC%2BC3MXpt1ygs74%3D 10.1016/j.neulet.2011.06.021 PMID:21704673
    • Haleagrahara N, Siew CJ, Mitra NK, Kumari M (2011) Neuroprotective effect of bioflavonoid quercetin in 6-hydroxydopamine-induced oxidative stress biomarkers in the rat striatum. Neurosci Lett 500:139-143, PMID:21704673
    • (2011) Neurosci Lett , vol.500 , pp. 139-143
    • Haleagrahara, N.1    Siew, C.J.2    Mitra, N.K.3    Kumari, M.4
  • 32
    • 0034596146 scopus 로고    scopus 로고
    • Pituitary-adrenal and autonomic responses to stress in women after sexual and physical abuse in childhood
    • 1:STN:280:DC%2BD3czpslKqsQ%3D%3D
    • Heim C, Newport DJ, Heit S, Graham YP, Wilcox M, Bonsall R, Miller AH, Nemeroff CB (2000) Pituitary-adrenal and autonomic responses to stress in women after sexual and physical abuse in childhood. J Am Med Assoc 284:592-597, PMID:10918705
    • (2000) J Am Med Assoc , vol.284 , pp. 592-597
    • Heim, C.1    Newport, D.J.2    Heit, S.3    Graham, Y.P.4    Wilcox, M.5    Bonsall, R.6    Miller, A.H.7    Nemeroff, C.B.8
  • 33
    • 10644277049 scopus 로고    scopus 로고
    • Protective effects of quercetin and vitamin C against oxidative stress-induced neurodegeneration
    • 15675797 1:CAS:528:DC%2BD2cXpsV2kurc%3D 10.1021/jf049243r PMID:15675797
    • Heo HJ, Lee CY (2004) Protective effects of quercetin and vitamin C against oxidative stress-induced neurodegeneration. J Agric Food Chem 52(25):7514-7517, PMID:15675797
    • (2004) J Agric Food Chem , vol.52 , Issue.25 , pp. 7514-7517
    • Heo, H.J.1    Lee, C.Y.2
  • 34
    • 0032819772 scopus 로고    scopus 로고
    • Dietary flavonoids: Intake, health effects and bioavailability
    • 10541448 1:CAS:528:DyaK1MXnsFSku7s%3D 10.1016/S0278-6915(99)00079-4 PMID:10541448
    • Hollman PC, Kata MB (1999) Dietary flavonoids: intake, health effects and bioavailability. Food Chem Toxicol 37(9-10):937-942, PMID:10541448
    • (1999) Food Chem Toxicol , vol.37 , Issue.9-10 , pp. 937-942
    • Hollman, P.C.1    Kata, M.B.2
  • 35
    • 58049115911 scopus 로고    scopus 로고
    • Preliminary results of a longitudinal study of changes in cognitive function in breast cancer patients undergoing chemotherapy with doxorubicin and cyclophosphamide
    • 10.1002/pon.1342 PMID:18506671
    • Jansen CE, Dodd MJ, Miaskowski CA, Dowling GA, Kramer J (2008) Preliminary results of a longitudinal study of changes in cognitive function in breast cancer patients undergoing chemotherapy with doxorubicin and cyclophosphamide. Psycho-Oncol 17:1189-1195, PMID:18506671
    • (2008) Psycho-Oncol , vol.17 , pp. 1189-1195
    • Jansen, C.E.1    Dodd, M.J.2    Miaskowski, C.A.3    Dowling, G.A.4    Kramer, J.5
  • 36
    • 77249104887 scopus 로고    scopus 로고
    • Butterfield da (2010) Alterations in brain antioxidant enzymes and redox proteomic identification of oxidized brain proteins induced by the anti-cancer drug adriamycin: Implications for oxidative stress-mediated chemobrain
    • 20096337 1:CAS:528:DC%2BC3cXis1ensbg%3D 2852883 10.1016/j.neuroscience.2010.01.021 PMID:20096337
    • Joshi G, Aluise CD, Cole MP, Sultana R, Pierce WM, Vore M, St Clair DK (2010) Butterfield DA (2010) Alterations in brain antioxidant enzymes and redox proteomic identification of oxidized brain proteins induced by the anti-cancer drug adriamycin: implications for oxidative stress-mediated chemobrain. Neuroscience 166(3):796-807, PMID:20096337
    • (2010) Neuroscience , vol.166 , Issue.3 , pp. 796-807
    • Joshi, G.1    Aluise, C.D.2    Cole, M.P.3    Sultana, R.4    Pierce, W.M.5    Vore, M.6    St Clair, D.K.7
  • 37
    • 33847307470 scopus 로고    scopus 로고
    • Glutathione elevation by gamma-glutamyl cysteine ethyl ester as a potential therapeutic strategy for preventing oxidative stress in brain mediated by in vivo administration of adriamycin: Implication for chemobrain
    • 17171703 1:CAS:528:DC%2BD2sXjtFOlurs%3D 10.1002/jnr.21158 PMID:17171703
    • Joshi G, Hardas S, Sultana R, St Clair DK, Vore M, Butterfield DA (2007) Glutathione elevation by gamma-glutamyl cysteine ethyl ester as a potential therapeutic strategy for preventing oxidative stress in brain mediated by in vivo administration of adriamycin: implication for chemobrain. J Neurosci Res 85:497-503, PMID:17171703
    • (2007) J Neurosci Res , vol.85 , pp. 497-503
    • Joshi, G.1    Hardas, S.2    Sultana, R.3    St Clair, D.K.4    Vore, M.5    Butterfield, D.A.6
  • 38
    • 27744462197 scopus 로고    scopus 로고
    • Free radical mediated oxidative stress and toxic side effects in brain induced by the anti cancer drug adriamycin: Insight into chemobrain
    • 16298740 1:CAS:528:DC%2BD2MXht1agtrnL 10.1080/10715760500143478 PMID:16298740
    • Joshi G, Sultana R, Tangpong J, Cole MP, St Clair DK, Vore M, Estus S, Butterfield DA (2005) Free radical mediated oxidative stress and toxic side effects in brain induced by the anti cancer drug adriamycin: insight into chemobrain. Free Radic Res 39:1147-1154, PMID:16298740
    • (2005) Free Radic Res , vol.39 , pp. 1147-1154
    • Joshi, G.1    Sultana, R.2    Tangpong, J.3    Cole, M.P.4    St Clair, D.K.5    Vore, M.6    Estus, S.7    Butterfield, D.A.8
  • 39
    • 77951499001 scopus 로고    scopus 로고
    • Suppressive effect of quercetin on acute stress-induced hypothalamic-pituitary-adrenal axis response in Wistar rats
    • 19423323 1:CAS:528:DC%2BC3cXks1Wqsbg%3D 10.1016/j.jnutbio.2009.01.008 PMID:19423323
    • Kawabata K, Kawai Y, Terao J (2010) Suppressive effect of quercetin on acute stress-induced hypothalamic-pituitary-adrenal axis response in Wistar rats. J Nutr Biochem 21:374-380, PMID:19423323
    • (2010) J Nutr Biochem , vol.21 , pp. 374-380
    • Kawabata, K.1    Kawai, Y.2    Terao, J.3
  • 40
    • 52049111222 scopus 로고    scopus 로고
    • Immunity and cognition: What do age-related dementia, HIV-dementia and 'chemo-brain' have in common?
    • 18789764 1:CAS:528:DC%2BD1cXhtFCksL%2FI 10.1016/j.it.2008.07.007 PMID:18789764
    • Kipnis J, Derecki NC, Yang C, Scrable H (2008) Immunity and cognition: what do age-related dementia, HIV-dementia and 'chemo-brain' have in common? Trends Immunol 29(10):455-463, PMID:18789764
    • (2008) Trends Immunol , vol.29 , Issue.10 , pp. 455-463
    • Kipnis, J.1    Derecki, N.C.2    Yang, C.3    Scrable, H.4
  • 41
    • 50049126606 scopus 로고    scopus 로고
    • Cognitive dysfunction induced by chronic administration of common cancer chemotherapeutics in rats
    • 18690526 1:CAS:528:DC%2BD1cXhtVSrsr3K 10.1007/s11011-008-9100-y PMID:18690526
    • Konat GW, Kraszpulski M, James I, Zhang HT, Abraham J (2008) Cognitive dysfunction induced by chronic administration of common cancer chemotherapeutics in rats. Metab Brain Dis 23:325-333, PMID:18690526
    • (2008) Metab Brain Dis , vol.23 , pp. 325-333
    • Konat, G.W.1    Kraszpulski, M.2    James, I.3    Zhang, H.T.4    Abraham, J.5
  • 42
    • 72049120388 scopus 로고    scopus 로고
    • Systemic administration of doxorubicin impairs aversively motivated memory in rats
    • 19747935 1:CAS:528:DC%2BD1MXht1yjtbvM 10.1016/j.pbb.2009.09.001 PMID:19747935
    • Liedke PE, Reolon GK, Kilpp B, Brunetto AL, Roesler R, Schwartsmann G (2009) Systemic administration of doxorubicin impairs aversively motivated memory in rats. Pharmacol Biochem Behav 94(2):239-243, PMID:19747935
    • (2009) Pharmacol Biochem Behav , vol.94 , Issue.2 , pp. 239-243
    • Liedke, P.E.1    Reolon, G.K.2    Kilpp, B.3    Brunetto, A.L.4    Roesler, R.5    Schwartsmann, G.6
  • 43
    • 33745377482 scopus 로고    scopus 로고
    • Quercetin reverses D-galactose induced neurotoxicity in mouse brain
    • 16707173 1:CAS:528:DC%2BD28Xms1Gls7g%3D 10.1016/j.bbr.2006.03.043 PMID:16707173
    • Lu J, Zheng YL, Luo L, Wu DM, Sun DX, Feng YJ (2006) Quercetin reverses D-galactose induced neurotoxicity in mouse brain. Behav Brain Res 171:251-260, PMID:16707173
    • (2006) Behav Brain Res , vol.171 , pp. 251-260
    • Lu, J.1    Zheng, Y.L.2    Luo, L.3    Wu, D.M.4    Sun, D.X.5    Feng, Y.J.6
  • 44
    • 0033969247 scopus 로고    scopus 로고
    • T-cell immunodeficiency following cytotoxic antineoplastic therapy: A review
    • 10661568 1:CAS:528:DC%2BD3cXhtVWgs7c%3D 10.1634/stemcells.18-1-10 PMID:10661568
    • Mackall CL (2000) T-cell immunodeficiency following cytotoxic antineoplastic therapy: a review. Stem Cells 18:10-18, PMID:10661568
    • (2000) Stem Cells , vol.18 , pp. 10-18
    • Mackall, C.L.1
  • 45
    • 2442430353 scopus 로고    scopus 로고
    • Polyphenols: Food sources and bioavailability
    • 15113710 1:CAS:528:DC%2BD2cXjs1ygsL4%3D PMID: 15113710
    • Manach C, Scalbert A, Morand C, Rémésy C, Jiménez L (2004) Polyphenols: food sources and bioavailability. Am J Clin Nutr 79:727-747, PMID: 15113710
    • (2004) Am J Clin Nutr , vol.79 , pp. 727-747
    • Manach, C.1    Scalbert, A.2    Morand, C.3    Rémésy, C.4    Jiménez, L.5
  • 46
    • 79959795613 scopus 로고    scopus 로고
    • Adriamycin-related anxiety-like behavior, brain oxidative stress and myelotoxicity in male Wistar rats
    • 21703296 1:CAS:528:DC%2BC3MXhtVWqtbfJ 10.1016/j.pbb.2011.06.015 PMID:21703296
    • Merzoug S, Toumi ML, Boukhris N, Baudin B, Tahraoui A (2011) Adriamycin-related anxiety-like behavior, brain oxidative stress and myelotoxicity in male Wistar rats. Pharmacol Biochem Behav 99:639-647, PMID:21703296
    • (2011) Pharmacol Biochem Behav , vol.99 , pp. 639-647
    • Merzoug, S.1    Toumi, M.L.2    Boukhris, N.3    Baudin, B.4    Tahraoui, A.5
  • 47
    • 34250816264 scopus 로고    scopus 로고
    • Quercetin inhibits expression of inflammatory cytokines through attenuation of NF-κB and p38 MAPK in HMC-1 human mast cell line
    • 17588137 1:CAS:528:DC%2BD2sXlvFKrs7s%3D 10.1007/s00011-007-6172-9 PMID:17588137
    • Min YD, Choi CH, Bark H, Son HY, Park HH, Lee S, Park JW, Park EK, Shin HI, Kim SH (2007) Quercetin inhibits expression of inflammatory cytokines through attenuation of NF-κB and p38 MAPK in HMC-1 human mast cell line. Inflamm Res 56:210-215, PMID:17588137
    • (2007) Inflamm Res , vol.56 , pp. 210-215
    • Min, Y.D.1    Choi, C.H.2    Bark, H.3    Son, H.Y.4    Park, H.H.5    Lee, S.6    Park, J.W.7    Park, E.K.8    Shin, H.I.9    Kim, S.H.10
  • 48
    • 9944219620 scopus 로고    scopus 로고
    • Synergistic interaction between ketoconazole and several antidepressant drugs with allopregnanolone treatments in ovariectomized Wistar rats forced to swim
    • 15588761 10.1016/j.pnpbp.2004.08.006 PMID:15588761
    • Molina-Hernández M, Tellez-Alcántara NP, Garcí JP, Lopez JIO, Jaramillo MT (2004) Synergistic interaction between ketoconazole and several antidepressant drugs with allopregnanolone treatments in ovariectomized Wistar rats forced to swim. Prog Neuropsychopharmacol Biol Psychiatry 28(8):1337-1345, PMID:15588761
    • (2004) Prog Neuropsychopharmacol Biol Psychiatry , vol.28 , Issue.8 , pp. 1337-1345
    • Molina-Hernández, M.1    Tellez-Alcántara, N.P.2    Garcí, J.P.3    Lopez, J.I.O.4    Jaramillo, M.T.5
  • 49
    • 0030945880 scopus 로고    scopus 로고
    • Disruptions of the hypothalamo-pituitary-adrenal axis increase anticancer drug lethality in the rat
    • 9217242 1:CAS:528:DyaK2sXktF2gu74%3D 10.1016/S0378-4274(97)00025-8 PMID:9217242
    • Navarra P, Preziosi P (1997) Disruptions of the hypothalamo-pituitary-adrenal axis increase anticancer drug lethality in the rat. Toxicol Lett 91:219-227, PMID:9217242
    • (1997) Toxicol Lett , vol.91 , pp. 219-227
    • Navarra, P.1    Preziosi, P.2
  • 50
    • 25444450345 scopus 로고    scopus 로고
    • Water-soluble derivative of propolis and its polyphenolic compounds enhance tumoricidal activity of macrophages
    • 16054317 10.1016/j.jep.2005.05.036 PMID:16054317
    • Oršolić N, Bašić I (2005) Water-soluble derivative of propolis and its polyphenolic compounds enhance tumoricidal activity of macrophages. J Ethnopharmacol 102:37-45, PMID:16054317
    • (2005) J Ethnopharmacol , vol.102 , pp. 37-45
    • Oršolić, N.1    Bašić, I.2
  • 51
    • 70350572330 scopus 로고    scopus 로고
    • Doxorubicin enhances CD4+ T-cell immune responses by inducing expression of CD40 ligand and 4-1BB
    • 19778641 1:CAS:528:DC%2BD1MXhtlygs77F 10.1016/j.intimp.2009.09.008 PMID:19778641
    • Park JY, Jang MJ, Chung YH, Kim KY, Kim SS, Lee WB, You S, Choi YS, Hur DY, Kim D (2009) Doxorubicin enhances CD4+ T-cell immune responses by inducing expression of CD40 ligand and 4-1BB. Int Immunopharmacol 9:1530-1539, PMID:19778641
    • (2009) Int Immunopharmacol , vol.9 , pp. 1530-1539
    • Park, J.Y.1    Jang, M.J.2    Chung, Y.H.3    Kim, K.Y.4    Kim, S.S.5    Lee, W.B.6    You, S.7    Choi, Y.S.8    Hur, D.Y.9    Kim, D.10
  • 52
    • 28544442541 scopus 로고    scopus 로고
    • Effects of prenatal stress on anxiety and social interactions in adult rats
    • 1:CAS:528:DC%2BD2MXht1Olsr3I
    • Patin V, Lordi B, Vincent A, Caston J (2005) Effects of prenatal stress on anxiety and social interactions in adult rats. Dev Brain Res 160:265-274, PMID:16290208
    • (2005) Dev Brain Res , vol.160 , pp. 265-274
    • Patin, V.1    Lordi, B.2    Vincent, A.3    Caston, J.4
  • 53
    • 32244448638 scopus 로고    scopus 로고
    • Determination of St. John's wort flavonoid-metabolites in rat brain through high performance liquid chromatography coupled with fluorescence detection
    • 1:CAS:528:DC%2BD28Xhtlarsbs%3D
    • Paulke A, Schubert-Zsilavecz M, Wurglics M (2006) Determination of St. John's wort flavonoid-metabolites in rat brain through high performance liquid chromatography coupled with fluorescence detection. J Chromatogr B Anal Technol Biomed Life Sci 832:109-113, PMID:16434241
    • (2006) J Chromatogr B Anal Technol Biomed Life Sci , vol.832 , pp. 109-113
    • Paulke, A.1    Schubert-Zsilavecz, M.2    Wurglics, M.3
  • 54
    • 0017618768 scopus 로고
    • Depression: A new animal model sensitive to antidepressant treatments
    • 559941 1:CAS:528:DyaE2sXkvFGhur4%3D 10.1038/266730a0 PMID:559941
    • Porsolt RD, Le Pichon M, Jalfre M (1977) Depression: a new animal model sensitive to antidepressant treatments. Nature 266:730-732, PMID:559941
    • (1977) Nature , vol.266 , pp. 730-732
    • Porsolt, R.D.1    Le Pichon, M.2    Jalfre, M.3
  • 55
    • 0029052184 scopus 로고
    • Lymphotoxicity and myelotoxicity of doxorubicin and SDZ PSC 833 combined chemotherapies for normal mice
    • 7610467 1:CAS:528:DyaK2MXlvFKqur8%3D 10.1016/0300-483X(95)03056-L PMID:7610467
    • Pourtier-Manzanedo A, Didier A, Froidevaux S, Loor F (1995) Lymphotoxicity and myelotoxicity of doxorubicin and SDZ PSC 833 combined chemotherapies for normal mice. Toxicology 99:207-217, PMID:7610467
    • (1995) Toxicology , vol.99 , pp. 207-217
    • Pourtier-Manzanedo, A.1    Didier, A.2    Froidevaux, S.3    Loor, F.4
  • 56
    • 40049098309 scopus 로고    scopus 로고
    • Anxiety and cognitive effects of quercetin liposomes in rats
    • 18249157 1:CAS:528:DC%2BC3cXmtVensQ%3D%3D 10.1016/j.nano.2007.12.001 PMID:18249157
    • Priprem A, Watanatorn J, Sutthiparinyanont S, Phachonpai W, Muchimapura S (2008) Anxiety and cognitive effects of quercetin liposomes in rats. Nanomedicine 4:70-78, PMID:18249157
    • (2008) Nanomedicine , vol.4 , pp. 70-78
    • Priprem, A.1    Watanatorn, J.2    Sutthiparinyanont, S.3    Phachonpai, W.4    Muchimapura, S.5
  • 57
    • 34548471990 scopus 로고    scopus 로고
    • Neuroprotective effects of quercetin and rutin on spatial memory impairment in an 8-arm radial maze task and neuronal death induced by repeated cerebral ischemia in rats
    • 17666865 1:CAS:528:DC%2BD2sXhtVaks7bP 10.1254/jphs.FP0070247 PMID:17666865
    • Pu F, Mishima K, Irie K, Motohashi K, Tanaka Y, Orito K, Egawa T, Kitamura Y, Egashira N, Iwasaki K, Fujiwara M (2007) Neuroprotective effects of quercetin and rutin on spatial memory impairment in an 8-arm radial maze task and neuronal death induced by repeated cerebral ischemia in rats. J Pharmacol Sci 104:329-334, PMID:17666865
    • (2007) J Pharmacol Sci , vol.104 , pp. 329-334
    • Pu, F.1    Mishima, K.2    Irie, K.3    Motohashi, K.4    Tanaka, Y.5    Orito, K.6    Egawa, T.7    Kitamura, Y.8    Egashira, N.9    Iwasaki, K.10    Fujiwara, M.11
  • 58
    • 80052934115 scopus 로고    scopus 로고
    • Antidepressant-like effect of a Ginkgo biloba extract (EGb761) in the mouse forced swimming test: Role of oxidative stress
    • 21672588 1:CAS:528:DC%2BC3MXhtFynsrfM 10.1016/j.neuint.2011.05.007 PMID:21672588
    • Rojas P, Serrano-García N, Medina-Campos ON, Pedraza-Chaverri J, Ögren SO, Rojas C (2011) Antidepressant-like effect of a Ginkgo biloba extract (EGb761) in the mouse forced swimming test: role of oxidative stress. Neurochem Int 59:628-636, PMID:21672588
    • (2011) Neurochem Int , vol.59 , pp. 628-636
    • Rojas, P.1    Serrano-García, N.2    Medina-Campos, O.N.3    Pedraza-Chaverri, J.4    Ögren, S.O.5    Rojas, C.6
  • 59
    • 81855164783 scopus 로고    scopus 로고
    • The flavonoid quercetin in disease prevention and therapy: Facts and fancies
    • 10.1016/j.bcp.2011.08.010 21856292 1:CAS:528:DC%2BC3MXhsFeisLfE 10.1016/j.bcp.2011.08.010
    • Russo M, Spagnuolo C, Tedesco I, Bilotto S, Russo GL (2012) The flavonoid quercetin in disease prevention and therapy: facts and fancies. Biochem Pharmacol 83:6-15. doi: 10.1016/j.bcp.2011.08.010
    • (2012) Biochem Pharmacol , vol.83 , pp. 6-15
    • Russo, M.1    Spagnuolo, C.2    Tedesco, I.3    Bilotto, S.4    Russo, G.L.5
  • 60
    • 33244467253 scopus 로고    scopus 로고
    • Factor analysis of forced swimming test, sucrose preference test and open field test on enriched, social and isolated reared rats
    • 10.1016/j.bbr.2005.12.001 PMID:16414129
    • Sáenz JCB, Villagra OR, Trías JF (2006) Factor analysis of forced swimming test, sucrose preference test and open field test on enriched, social and isolated reared rats. Behav Brain Res 169:57-65, PMID:16414129
    • (2006) Behav Brain Res , vol.169 , pp. 57-65
    • Sáenz, J.C.B.1    Villagra, O.R.2    Trías, J.F.3
  • 61
    • 0035368550 scopus 로고    scopus 로고
    • Characterization of cytosolic glutathione S-transferase in cultured astrocytes
    • 11384612 1:CAS:528:DC%2BD3MXjvV2qs70%3D 10.1016/S0006-8993(01)02384-8 PMID:11384612
    • Sagara J, Sugita Y (2001) Characterization of cytosolic glutathione S-transferase in cultured astrocytes. Brain Res 902:190-197, PMID:11384612
    • (2001) Brain Res , vol.902 , pp. 190-197
    • Sagara, J.1    Sugita, Y.2
  • 62
    • 38549146292 scopus 로고    scopus 로고
    • Antidepressant-like effect of onion (Allium cepa L.) powder in a rat behavioral model of depression
    • 18175926 1:CAS:528:DC%2BD1cXhvF2ksrk%3D 10.1271/bbb.70454 PMID:18175926
    • Sakakibara H, Yoshino S, Kawai Y, Terao J (2008) Antidepressant-like effect of onion (Allium cepa L.) powder in a rat behavioral model of depression. Biosci Biotechnol Biochem 72:94-100, PMID:18175926
    • (2008) Biosci Biotechnol Biochem , vol.72 , pp. 94-100
    • Sakakibara, H.1    Yoshino, S.2    Kawai, Y.3    Terao, J.4
  • 63
    • 0030867845 scopus 로고    scopus 로고
    • Quercetin, a bioflavonoid, inhibits the induction of interleukin 8 and monocyte chemoattractant protein-1 expression by tumor necrosis factor-α in cultured human synovial cells
    • 9292787 1:CAS:528:DyaK2sXmtlCrtbY%3D PMID:9292787
    • Sato M, Miyazaki T, Kambe F, Maeda K, Seo H (1997) Quercetin, a bioflavonoid, inhibits the induction of interleukin 8 and monocyte chemoattractant protein-1 expression by tumor necrosis factor-α in cultured human synovial cells. J Rheumatol 24:1680-1684, PMID:9292787
    • (1997) J Rheumatol , vol.24 , pp. 1680-1684
    • Sato, M.1    Miyazaki, T.2    Kambe, F.3    Maeda, K.4    Seo, H.5
  • 64
    • 0028299741 scopus 로고
    • Thigmotaxis as an index of anxiety in mice. Influence of dopaminergic transmissions
    • 7913324 1:CAS:528:DyaK2cXlt1Gkur0%3D 10.1016/0166-4328(94)90008-6 PMID:7913324
    • Simon P, Dupuis R, Costentin J (1994) Thigmotaxis as an index of anxiety in mice. Influence of dopaminergic transmissions. Behav Brain Res 61(1):59-64, PMID:7913324
    • (1994) Behav Brain Res , vol.61 , Issue.1 , pp. 59-64
    • Simon, P.1    Dupuis, R.2    Costentin, J.3
  • 65
    • 0142180034 scopus 로고    scopus 로고
    • Reversal of aging and chronic ethanol-induced cognitive dysfunction by quercetin a bioflavonoid
    • 14703737 1:CAS:528:DC%2BD3sXoslelsLg%3D 10.1080/10715760310001616014 PMID:14703737
    • Singh A, Naidu PS, Kulkarni SK (2003) Reversal of aging and chronic ethanol-induced cognitive dysfunction by quercetin a bioflavonoid. Free Radic Res 37(11):1245-1252, PMID:14703737
    • (2003) Free Radic Res , vol.37 , Issue.11 , pp. 1245-1252
    • Singh, A.1    Naidu, P.S.2    Kulkarni, S.K.3
  • 66
    • 0028151186 scopus 로고
    • The effect of stressful behavioral exposure on endocrine and immune parameters in the rat
    • 10.1002/smi.2460100406 10.1002/smi.2460100406
    • Song C, Kelly JP, Leonard BE (1994) The effect of stressful behavioral exposure on endocrine and immune parameters in the rat. Stress Med 10:239-245. doi: 10.1002/smi.2460100406
    • (1994) Stress Med , vol.10 , pp. 239-245
    • Song, C.1    Kelly, J.P.2    Leonard, B.E.3
  • 67
    • 0037013196 scopus 로고    scopus 로고
    • Flavonoid inhibition of sodium-dependent vitamin C transporter 1 (SVCT1) and glucose transporter isoform 2 (GLUT2), intestinal transporters for vitamin C and glucose
    • 10.1074/jbc.M110496200 11834736 1:CAS:528:DC%2BD38Xjs1SqtL0%3D 10.1074/jbc.M110496200
    • Song J, Kwon O, Chen S, Daruwala R, Eck P, Park JB, Levine M (2002) Flavonoid inhibition of sodium-dependent vitamin C transporter 1 (SVCT1) and glucose transporter isoform 2 (GLUT2), intestinal transporters for vitamin C and glucose. J Biol Chem 277(18):15252-15260. doi: 10.1074/jbc.M110496200
    • (2002) J Biol Chem , vol.277 , Issue.18 , pp. 15252-15260
    • Song, J.1    Kwon, O.2    Chen, S.3    Daruwala, R.4    Eck, P.5    Park, J.B.6    Levine, M.7
  • 68
    • 38349008651 scopus 로고    scopus 로고
    • The interactions of flavonoids within neuronal signalling pathways
    • 18850181 1:CAS:528:DC%2BD1MXhtF2is7zI 2474943 10.1007/s12263-007-0056-z PMID:18850181
    • Spencer JP (2007) The interactions of flavonoids within neuronal signalling pathways. Genes Nutr 2:257-273, PMID:18850181
    • (2007) Genes Nutr , vol.2 , pp. 257-273
    • Spencer, J.P.1
  • 69
    • 0036168728 scopus 로고    scopus 로고
    • Chemotherapy-induced immunosuppression and reconstitution of immune function
    • 11839388 1:CAS:528:DC%2BD38XhtFyktLw%3D 10.1016/S0145-2126(01)00138-2 PMID:11839388
    • Steele TA (2002) Chemotherapy-induced immunosuppression and reconstitution of immune function. Leuk Res 26:411-414, PMID:11839388
    • (2002) Leuk Res , vol.26 , pp. 411-414
    • Steele, T.A.1
  • 70
    • 33947644871 scopus 로고    scopus 로고
    • Protein oxidation and lipid peroxidation in brain of subjects with Alzheimer's disease: Insights into mechanism of neurodegeneration from redox proteomics
    • 17034347 1:CAS:528:DC%2BD28XhtVKntb%2FO 10.1089/ars.2006.8.2021 PMID:17034347
    • Sultana R, Perluigi M, Butterfield DA (2006) Protein oxidation and lipid peroxidation in brain of subjects with Alzheimer's disease: insights into mechanism of neurodegeneration from redox proteomics. Antioxid Redox Signal 8:2021-2037, PMID:17034347
    • (2006) Antioxid Redox Signal , vol.8 , pp. 2021-2037
    • Sultana, R.1    Perluigi, M.2    Butterfield, D.A.3
  • 71
    • 33947154868 scopus 로고    scopus 로고
    • Quercetin attenuates spontaneous behavior and spatial memory impairment in D-galactose-treated mice by increasing brain antioxidant capacity
    • 10.1016/j.nutres.2007.01.010 1:CAS:528:DC%2BD2sXjsVWnt7c%3D 10.1016/j.nutres.2007.01.010
    • Sun SW, Yu HQ, Zhang H, Zheng YL, Wang JJ, Luo L (2007) Quercetin attenuates spontaneous behavior and spatial memory impairment in D-galactose-treated mice by increasing brain antioxidant capacity. Nutr Res 27:169-175. doi: 10.1016/j.nutres.2007.01.010
    • (2007) Nutr Res , vol.27 , pp. 169-175
    • Sun, S.W.1    Yu, H.Q.2    Zhang, H.3    Zheng, Y.L.4    Wang, J.J.5    Luo, L.6
  • 72
    • 33846203801 scopus 로고    scopus 로고
    • Adriamycin-mediated nitration of manganese superoxide dismutase in the central nervous system: Insight into the mechanism of chemobrain
    • 17227439 1:CAS:528:DC%2BD2sXptl2jtQ%3D%3D 10.1111/j.1471-4159.2006.04179.x PMID:17227439
    • Tangpong J, Cole MP, Sultana R, Estus S, Vore M, St Clair W, Ratanachaiyavong S, St Clair DK, Butterfield DA (2007) Adriamycin-mediated nitration of manganese superoxide dismutase in the central nervous system: insight into the mechanism of chemobrain. J Neurochem 100:191-201, PMID:17227439
    • (2007) J Neurochem , vol.100 , pp. 191-201
    • Tangpong, J.1    Cole, M.P.2    Sultana, R.3    Estus, S.4    Vore, M.5    St Clair, W.6    Ratanachaiyavong, S.7    St Clair, D.K.8    Butterfield, D.A.9
  • 74
    • 84877072932 scopus 로고    scopus 로고
    • Quercetin alleviates predator stress-induced anxiety-like and brain oxidative signs in pregnant rats and immune count disturbance in their offspring
    • 23541492 1:CAS:528:DC%2BC3sXnsFWis7k%3D 10.1016/j.pbb.2013.03.009 PMID:23541492
    • Toumi ML, Merzoug S, Baudin B, Tahraoui A (2013) Quercetin alleviates predator stress-induced anxiety-like and brain oxidative signs in pregnant rats and immune count disturbance in their offspring. Pharmacol Biochem Behav 107:1-10, PMID:23541492
    • (2013) Pharmacol Biochem Behav , vol.107 , pp. 1-10
    • Toumi, M.L.1    Merzoug, S.2    Baudin, B.3    Tahraoui, A.4
  • 75
    • 36148985744 scopus 로고    scopus 로고
    • Chemotherapy-induced immunosuppression is restored by a fermented soybean extract: A proof of concept clinical trial
    • 10.1016/j.nutres.2007.09.001 1:CAS:528:DC%2BD2sXhtlagsrrM 10.1016/j.nutres.2007.09.001
    • Tsang YW, Chi KH, Hu CJ, Tseng CL, Tseng FW, Wang YS (2007) Chemotherapy-induced immunosuppression is restored by a fermented soybean extract: a proof of concept clinical trial. Nutr Res 27:679-684. doi: 10.1016/j.nutres.2007.09.001
    • (2007) Nutr Res , vol.27 , pp. 679-684
    • Tsang, Y.W.1    Chi, K.H.2    Hu, C.J.3    Tseng, C.L.4    Tseng, F.W.5    Wang, Y.S.6
  • 76
    • 67651115644 scopus 로고    scopus 로고
    • Vinblastine and doxorubicin administration to pregnant mice affects brain development and behaviour in the offspring
    • 19422850 10.1016/j.neuro.2009.04.009 PMID:19422850
    • Van Calsteren K, Hartmann D, Van Aerschot L, Verbesselt R, Van Bree R, D'Hooge R, Amant F (2009) Vinblastine and doxorubicin administration to pregnant mice affects brain development and behaviour in the offspring. Neurotoxicology 30:647-657, PMID:19422850
    • (2009) Neurotoxicology , vol.30 , pp. 647-657
    • Van Calsteren, K.1    Hartmann, D.2    Van Aerschot, L.3    Verbesselt, R.4    Van Bree, R.5    D'Hooge, R.6    Amant, F.7
  • 77
    • 8844236064 scopus 로고    scopus 로고
    • Identification of 14 quercetin phase II mono- and mixed conjugates and their formation by rat and human phase II in vitro model systems
    • 15540950 10.1021/tx049826v PMID:15540950
    • van der Woude H, Boersma MG, Vervoort J, Rietjens IM (2004) Identification of 14 quercetin phase II mono- and mixed conjugates and their formation by rat and human phase II in vitro model systems. Chem Res Toxicol 17(11):1520-1530, PMID:15540950
    • (2004) Chem Res Toxicol , vol.17 , Issue.11 , pp. 1520-1530
    • Van Der Woude, H.1    Boersma, M.G.2    Vervoort, J.3    Rietjens, I.M.4
  • 78
    • 73849114860 scopus 로고    scopus 로고
    • Intranasal administration of quercetin liposome decreases anxiety-like behavior and increases spatial memory
    • 10.3844/ajabssp.2007.31.35 10.3844/ajabssp.2007.31.35
    • Wattanathorn J, Phachonpai W, Priprem A, Suthiparinyanont S (2007) Intranasal administration of quercetin liposome decreases anxiety-like behavior and increases spatial memory. Am J Agric Biol Sci 2(1):31-35. doi: 10.3844/ajabssp.2007.31.35
    • (2007) Am J Agric Biol Sci , vol.2 , Issue.1 , pp. 31-35
    • Wattanathorn, J.1    Phachonpai, W.2    Priprem, A.3    Suthiparinyanont, S.4
  • 79
    • 0036197846 scopus 로고    scopus 로고
    • Treatment of multiple sclerosis with cyclophosphamide: Critical review of clinical and immunologic effects
    • 11990872 1:CAS:528:DC%2BD38Xjt1Chs7c%3D 10.1191/1352458502ms790oa PMID:11990872
    • Weiner HL, Cohen JA (2002) Treatment of multiple sclerosis with cyclophosphamide: critical review of clinical and immunologic effects. Mult Scler 8:142-154, PMID:11990872
    • (2002) Mult Scler , vol.8 , pp. 142-154
    • Weiner, H.L.1    Cohen, J.A.2
  • 80
    • 1642617750 scopus 로고    scopus 로고
    • Catecholamine-induced interleukin-10 release: A key mechanism in systemic immunodepression after brain injury
    • 10.1186/cc375 137244 10.1186/cc375
    • Woiciechowsky C, Schoning B, Lanksch WR, Volk HD, Docke WD (1999) Catecholamine-induced interleukin-10 release: a key mechanism in systemic immunodepression after brain injury. Crit Care 3:R107-R111. doi: 10.1186/cc375
    • (1999) Crit Care , vol.3 , pp. 107-R111
    • Woiciechowsky, C.1    Schoning, B.2    Lanksch, W.R.3    Volk, H.D.4    Docke, W.D.5
  • 81
    • 7444253369 scopus 로고    scopus 로고
    • Flavonoids and the brain: Interactions at the blood-brain barrier and their physiological effects on the central nervous system
    • 15528027 1:CAS:528:DC%2BD2cXpsFWku7g%3D 10.1016/j.freeradbiomed.2004.08.002 PMID:15528027
    • Youdim KA, Shukitt-Hale B, Joseph JA (2004) Flavonoids and the brain: interactions at the blood-brain barrier and their physiological effects on the central nervous system. Free Radic Biol Med 37:1683-1693, PMID:15528027
    • (2004) Free Radic Biol Med , vol.37 , pp. 1683-1693
    • Youdim, K.A.1    Shukitt-Hale, B.2    Joseph, J.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.