-
1
-
-
33745684527
-
Metastasis: A question of life or death
-
Mehlen, P.; Puisieux, A. Metastasis: A question of life or death. Nat. Rev. Cancer 2006, 6, 449–458.
-
(2006)
Nat. Rev. Cancer
, vol.6
, pp. 449-458
-
-
Mehlen, P.1
Puisieux, A.2
-
2
-
-
77950591041
-
Cancer stemness and metastasis: Therapeutic consequences and perspectives
-
Monteiro, J.; Fodde, R. Cancer stemness and metastasis: Therapeutic consequences and perspectives. Eur J. Cancer 2010, 46, 1198–1203.
-
(2010)
Eur J. Cancer
, vol.46
, pp. 1198-1203
-
-
Monteiro, J.1
Fodde, R.2
-
3
-
-
63049090100
-
Metastasis: From dissemination to organ-specific colonization
-
Nguyen, D.X.; Bos, P.D.; Massague, J. Metastasis: From dissemination to organ-specific colonization. Nat. Rev. Cancer 2009, 9, 274–284.
-
(2009)
Nat. Rev. Cancer
, vol.9
, pp. 274-284
-
-
Nguyen, D.X.1
Bos, P.D.2
Massague, J.3
-
4
-
-
84906922339
-
Metastatic cancer stem cells: From the concept to therapeutics
-
Liao, W.T.; Ye, Y.P.; Deng, Y.J.; Bian, X.W.; Ding, Y.Q. Metastatic cancer stem cells: From the concept to therapeutics. Am. J. Stem. Cells 2014, 3, 46–62.
-
(2014)
Am. J. Stem. Cells
, vol.3
, pp. 46-62
-
-
Liao, W.T.1
Ye, Y.P.2
Deng, Y.J.3
Bian, X.W.4
Ding, Y.Q.5
-
5
-
-
84861185907
-
Molecular networks that regulate cancer metastasis
-
Spano, D.; Heck, C.; de Antonellis, P.; Christofori, G.; Zollo, M. Molecular networks that regulate cancer metastasis. Semin. Cancer Biol. 2012, 22, 234–249.
-
(2012)
Semin. Cancer Biol
, vol.22
, pp. 234-249
-
-
Spano, D.1
Heck, C.2
De Antonellis, P.3
Christofori, G.4
Zollo, M.5
-
6
-
-
40549142736
-
Environmental restrictions within tumor ecosystems select for a convergent, hypoxia-resistant phenotype of cancer stem cells
-
Olivotto, M.; Dello Sbarba, P. Environmental restrictions within tumor ecosystems select for a convergent, hypoxia-resistant phenotype of cancer stem cells. Cell Cycle 2008, 7, 176–187.
-
(2008)
Cell Cycle
, vol.7
, pp. 176-187
-
-
Olivotto, M.1
Dello Sbarba, P.2
-
7
-
-
45849089879
-
Exploring the role of cancer stem cells in radioresistance
-
Baumann, M.; Krause, M.; Hill, R. Exploring the role of cancer stem cells in radioresistance. Nat. Rev. Cancer 2008, 8, 545–554.
-
(2008)
Nat. Rev. Cancer
, vol.8
, pp. 545-554
-
-
Baumann, M.1
Krause, M.2
Hill, R.3
-
8
-
-
59049105873
-
Die hard: Are cancer stem cells the bruce willises of tumor biology?
-
Fabian, A.; Barok, M.; Vereb, G.; Szollosi, J. Die hard: Are cancer stem cells the bruce willises of tumor biology? Cytometry A 2009, 75, 67–74.
-
(2009)
Cytometry A
, vol.75
, pp. 67-74
-
-
Fabian, A.1
Barok, M.2
Vereb, G.3
Szollosi, J.4
-
9
-
-
33846239456
-
Beyond tumorigenesis: Cancer stem cells in metastasis
-
Li, F.; Tiede, B.; Massague, J.; Kang, Y. Beyond tumorigenesis: Cancer stem cells in metastasis. Cell Res. 2007, 17, 3–14.
-
(2007)
Cell Res
, vol.17
, pp. 3-14
-
-
Li, F.1
Tiede, B.2
Massague, J.3
Kang, Y.4
-
10
-
-
34748866686
-
Brivanlou, A.H. Signaling pathways in cancer and embryonic stem cells
-
Dreesen, O.; Brivanlou, A.H. Signaling pathways in cancer and embryonic stem cells. Stem. Cell Rev. 2007, 3, 7–17.
-
(2007)
Stem. Cell Rev
, vol.3
, pp. 7-17
-
-
Dreesen, O.1
-
11
-
-
3042697038
-
Hyaluronan: From extracellular glue to pericellular cue
-
Toole, B.P. Hyaluronan: From extracellular glue to pericellular cue. Nat. Rev. Cancer 2004, 4, 528–539.
-
(2004)
Nat. Rev. Cancer
, vol.4
, pp. 528-539
-
-
Toole, B.P.1
-
12
-
-
22844436226
-
Recent advances in tumor-targeting anticancer drug conjugates
-
Jaracz, S.; Chen, J.; Kuznetsova, L.V.; Ojima, I. Recent advances in tumor-targeting anticancer drug conjugates. Bioorg. Med. Chem. 2005, 13, 5043–5054.
-
(2005)
Bioorg. Med. Chem
, vol.13
, pp. 5043-5054
-
-
Jaracz, S.1
Chen, J.2
Kuznetsova, L.V.3
Ojima, I.4
-
13
-
-
33751270222
-
Heparanase, hyaluronan, and CD44 in cancers: A breast carcinoma perspective
-
Gotte, M.; Yip, G.W. Heparanase, hyaluronan, and CD44 in cancers: A breast carcinoma perspective. Cancer Res. 2006, 66, 10233–10237.
-
(2006)
Cancer Res
, vol.66
, pp. 10233-10237
-
-
Gotte, M.1
Yip, G.W.2
-
14
-
-
25844473391
-
The over-expression of HAS2, Hyal-2 and CD44 is implicated in the invasiveness of breast cancer
-
Udabage, L.; Brownlee, G.R.; Nilsson, S.K.; Brown, T.J. The over-expression of HAS2, Hyal-2 and CD44 is implicated in the invasiveness of breast cancer. Exp. Cell Res. 2005, 310, 205–217.
-
(2005)
Exp. Cell Res
, vol.310
, pp. 205-217
-
-
Udabage, L.1
Brownlee, G.R.2
Nilsson, S.K.3
Brown, T.J.4
-
15
-
-
0025688587
-
Extracellular matrix proteins and their receptors in the normal, hyperplastic and neoplastic breast
-
Gould, V.E.; Koukoulis, G.K.; Virtanen, I. Extracellular matrix proteins and their receptors in the normal, hyperplastic and neoplastic breast. Cell Differ. Dev. 1990, 32, 409–416.
-
(1990)
Cell Differ. Dev
, vol.32
, pp. 409-416
-
-
Gould, V.E.1
Koukoulis, G.K.2
Virtanen, I.3
-
16
-
-
84921937568
-
Pigment epithelium-derived factor (PEDF) inhibits breast cancer metastasis by down-regulating fibronectin
-
Hong, H.; Zhou, T.; Fang, S.; Jia, M.; Xu, Z.; Dai, Z.; Li, C.; Li, S.; Li, L.; Zhang, T.; et al. Pigment epithelium-derived factor (PEDF) inhibits breast cancer metastasis by down-regulating fibronectin. Breast Cancer Res. Treat. 2014, 148, 61–72.
-
(2014)
Breast Cancer Res. Treat
, vol.148
, pp. 61-72
-
-
Hong, H.1
Zhou, T.2
Fang, S.3
Jia, M.4
Xu, Z.5
Dai, Z.6
Li, C.7
Li, S.8
Li, L.9
Zhang, T.10
-
17
-
-
84899561595
-
Hsp90 binds directly to fibronectin (FN) and inhibition reduces the extracellular fibronectin matrix in breast cancer cells
-
Hunter, M.C.; O’Hagan, K.L.; Kenyon, A.; Dhanani, K.C.; Prinsloo, E.; Edkins, A.L. Hsp90 binds directly to fibronectin (FN) and inhibition reduces the extracellular fibronectin matrix in breast cancer cells. PLOS ONE 2014, 9, e86842.
-
(2014)
PLOS ONE
, vol.9
-
-
Hunter, M.C.1
O’Hagan, K.L.2
Kenyon, A.3
Dhanani, K.C.4
Prinsloo, E.5
Edkins, A.L.6
-
18
-
-
0036892112
-
Immunohistochemical expression of extracellular matrix components tenascin, fibronectin, collagen type IV and laminin in breast cancer: Their prognostic value and role in tumour invasion and progression
-
Ioachim, E.; Charchanti, A.; Briasoulis, E.; Karavasilis, V.; Tsanou, H.; Arvanitis, D.L.; Agnantis, N.J.; Pavlidis, N. Immunohistochemical expression of extracellular matrix components tenascin, fibronectin, collagen type IV and laminin in breast cancer: Their prognostic value and role in tumour invasion and progression. Eur. J. Cancer 2002, 38, 2362-2370.
-
(2002)
Eur. J. Cancer
, vol.38
, pp. 2362-2370
-
-
Ioachim, E.1
Charchanti, A.2
Briasoulis, E.3
Karavasilis, V.4
Tsanou, H.5
Arvanitis, D.L.6
Agnantis, N.J.7
Pavlidis, N.8
-
19
-
-
28844459379
-
Fibronectin fibrillogenesis, a cell-mediated matrix assembly process
-
Mao, Y.; Schwarzbauer, J.E. Fibronectin fibrillogenesis, a cell-mediated matrix assembly process. Matrix Biol. 2005, 24, 389-399.
-
(2005)
Matrix Biol
, vol.24
, pp. 389-399
-
-
Mao, Y.1
Schwarzbauer, J.E.2
-
20
-
-
1542373992
-
Fibronectin matrix assembly regulates a5p1-mediated cell cohesion
-
Robinson, E.E.; Foty, R.A.; Corbett, S.A. Fibronectin matrix assembly regulates a5p1-mediated cell cohesion. Mol. Biol. Cell 2004, 15, 973-981.
-
(2004)
Mol. Biol. Cell
, vol.15
, pp. 973-981
-
-
Robinson, E.E.1
Foty, R.A.2
Corbett, S.A.3
-
21
-
-
0042887252
-
The ins and outs of fibronectin matrix assembly
-
Wierzbicka-Patynowski, I.; Schwarzbauer, J.E. The ins and outs of fibronectin matrix assembly. J. Cell Sci. 2003, 116, 3269-3276.
-
(2003)
J. Cell Sci
, vol.116
, pp. 3269-3276
-
-
Wierzbicka-Patynowski, I.1
Schwarzbauer, J.E.2
-
22
-
-
84884412852
-
Fibronectin expression in carcinoma cells correlates with tumor aggressiveness and poor clinical outcome in patients with invasive breast cancer
-
Bae, Y.K.; Kim, A.; Kim, M.K.; Choi, J.E.; Kang, S.H.; Lee, S.J. Fibronectin expression in carcinoma cells correlates with tumor aggressiveness and poor clinical outcome in patients with invasive breast cancer. Hum. Pathol. 2013, 44, 2028-2037.
-
(2013)
Hum. Pathol.
, vol.44
, pp. 2028-2037
-
-
Bae, Y.K.1
Kim, A.2
Kim, M.K.3
Choi, J.E.4
Kang, S.H.5
Lee, S.J.6
-
23
-
-
39149084984
-
Rapid expression and activation of MMP-2 and MMP-9 upon exposure of human breast cancer cells (MCF-7) to fibronectin in serum free medium
-
Das, S.; Banerji, A.; Frei, E.; Chatterjee, A. Rapid expression and activation of MMP-2 and MMP-9 upon exposure of human breast cancer cells (MCF-7) to fibronectin in serum free medium. Life Sci. 2008, 82, 467-476.
-
(2008)
Life Sci
, vol.82
, pp. 467-476
-
-
Das, S.1
Banerji, A.2
Frei, E.3
Chatterjee, A.4
-
24
-
-
78751571123
-
Culture of human breast cancer cell line (MDA-MB-231) on fibronectin-coated surface induces pro-matrix metalloproteinase-9 expression and activity
-
Maity, G.; Choudhury, P.R.; Sen, T.; Ganguly, K.K.; Sil, H.; Chatterjee, A. Culture of human breast cancer cell line (MDA-MB-231) on fibronectin-coated surface induces pro-matrix metalloproteinase-9 expression and activity. Tumour Biol. 2011, 32, 129-138.
-
(2011)
Tumour Biol
, vol.32
, pp. 129-138
-
-
Maity, G.1
Choudhury, P.R.2
Sen, T.3
Ganguly, K.K.4
Sil, H.5
Chatterjee, A.6
-
25
-
-
11144227593
-
Small integrin binding ligand n-linked glycoprotein gene family expression in different cancers
-
Fisher, L.W.; Jain, A.; Tayback, M.; Fedarko, N.S. Small integrin binding ligand n-linked glycoprotein gene family expression in different cancers. Clin. Cancer Res. 2004, 10, 8501-8511.
-
(2004)
Clin. Cancer Res
, vol.10
, pp. 8501-8511
-
-
Fisher, L.W.1
Jain, A.2
Tayback, M.3
Fedarko, N.S.4
-
26
-
-
38549097166
-
Osteopontin: Regulation in tumor metastasis
-
Wai, P.Y.; Kuo, P.C. Osteopontin: Regulation in tumor metastasis. Cancer Metastasis Rev. 2008, 27, 103-118.
-
(2008)
Cancer Metastasis Rev
, vol.27
, pp. 103-118
-
-
Wai, P.Y.1
Kuo, P.C.2
-
27
-
-
0028816321
-
Increased expression of osteonectin and osteopontin, two bone matrix proteins, in human breast cancer
-
Bellahcene, A.; Castronovo, V. Increased expression of osteonectin and osteopontin, two bone matrix proteins, in human breast cancer. Am. J. Pathol. 1995, 146, 95-100.
-
(1995)
Am. J. Pathol.
, vol.146
, pp. 95-100
-
-
Bellahcene, A.1
Castronovo, V.2
-
28
-
-
0027980795
-
Osteopontin expression and distribution in human carcinomas
-
Brown, L.F.; Papadopoulos-Sergiou, A.; Berse, B.; Manseau, E.J.; Tognazzi, K.; Perruzzi, C.A.; Dvorak, H.F.; Senger, D.R. Osteopontin expression and distribution in human carcinomas. Am. J. Pathol. 1994, 145, 610-623.
-
(1994)
Am. J. Pathol
, vol.145
, pp. 610-623
-
-
Brown, L.F.1
Papadopoulos-Sergiou, A.2
Berse, B.3
Manseau, E.J.4
Tognazzi, K.5
Perruzzi, C.A.6
Dvorak, H.F.7
Senger, D.R.8
-
29
-
-
0030843339
-
Ras mutation and expression of the ras-regulated genes osteopontin and cathepsin l in human esophageal cancer
-
Casson, A.G; Wilson, S.M.; McCart, J.A.; O’Malley, F.P.; Ozcelik, H.; Tsao, M.S.; Chambers, A.F. Ras mutation and expression of the ras-regulated genes osteopontin and cathepsin l in human esophageal cancer. Int. J. Cancer 1997, 72, 739-745.
-
(1997)
Int. J. Cancer
, vol.72
, pp. 739-745
-
-
Casson, A.G.1
Wilson, S.M.2
McCart, J.A.3
O’Malley, F.P.4
Ozcelik, H.5
Tsao, M.S.6
Chambers, A.F.7
-
30
-
-
0036229416
-
Overexpression of osteopontin in hepatocellular carcinoma
-
Gotoh, M.; Sakamoto, M.; Kanetaka, K.; Chuuma, M.; Hirohashi, S. Overexpression of osteopontin in hepatocellular carcinoma. Pathol. Int. 2002, 52, 19-24.
-
(2002)
Pathol. Int
, vol.52
, pp. 19-24
-
-
Gotoh, M.1
Sakamoto, M.2
Kanetaka, K.3
Chuuma, M.4
Hirohashi, S.5
-
31
-
-
0028843443
-
Expression of bone matrix protein messenger ribonucleic acids in human breast cancers. Possible involvement of osteopontin in development of calcifying foci
-
Hirota, S.; Ito, A.; Nagoshi, J.; Takeda, M.; Kurata, A.; Takatsuka, Y.; Kohri, K.; Nomura, S.; Kitamura, Y. Expression of bone matrix protein messenger ribonucleic acids in human breast cancers. Possible involvement of osteopontin in development of calcifying foci. Lab. Invest. 1995, 72, 64-69.
-
(1995)
Lab. Invest
, vol.72
, pp. 64-69
-
-
Hirota, S.1
Ito, A.2
Nagoshi, J.3
Takeda, M.4
Kurata, A.5
Takatsuka, Y.6
Kohri, K.7
Nomura, S.8
Kitamura, Y.9
-
32
-
-
0023695494
-
Secreted phosphoproteins associated with neoplastic transformation: Close homology with plasma proteins cleaved during blood coagulation
-
Senger, D.R.; Perruzzi, C.A.; Gracey, C.F.; Papadopoulos, A.; Tenen, D.G. Secreted phosphoproteins associated with neoplastic transformation: Close homology with plasma proteins cleaved during blood coagulation. Cancer Res. 1988, 48, 5770-5774.
-
(1988)
Cancer Res
, vol.48
, pp. 5770-5774
-
-
Senger, D.R.1
Perruzzi, C.A.2
Gracey, C.F.3
Papadopoulos, A.4
Tenen, D.G.5
-
33
-
-
0030988805
-
Harris, J.F. Elevated plasma osteopontin in metastatic breast cancer associated with increased tumor burden and decreased survival
-
Singhal, H.; Bautista, D.S.; Tonkin, K.S.; O’Malley, F.P.; Tuck, A.B.; Chambers, A.F.; Harris, J.F. Elevated plasma osteopontin in metastatic breast cancer associated with increased tumor burden and decreased survival. Clin. Cancer Res. 1997, 3, 605-611.
-
(1997)
Clin. Cancer Res
, vol.3
, pp. 605-611
-
-
Singhal, H.1
Bautista, D.S.2
Tonkin, K.S.3
O’Malley, F.P.4
Tuck, A.B.5
Chambers, A.F.6
-
34
-
-
0031662496
-
Osteopontin expression in a group of lymph node negative breast cancer patients
-
Tuck, A.B.; O’Malley, F.P.; Singhal, H.; Harris, J.F.; Tonkin, K.S.; Kerkvliet, N.; Saad, Z.; Doig, G.S.; Chambers, A.F. Osteopontin expression in a group of lymph node negative breast cancer patients. Int. J. Cancer 1998, 79, 502-508.
-
(1998)
Int. J. Cancer
, vol.79
, pp. 502-508
-
-
Tuck, A.B.1
O’Malley, F.P.2
Singhal, H.3
Harris, J.F.4
Tonkin, K.S.5
Kerkvliet, N.6
Saad, Z.7
Doig, G.S.8
Chambers, A.F.9
-
35
-
-
33745187759
-
Serial plasma osteopontin levels have prognostic value in metastatic breast cancer
-
Bramwell, V.H.; Doig, G.S.; Tuck, A.B.; Wilson, S.M.; Tonkin, K.S.; Tomiak, A.; Perera, F.; Vandenberg, T.A.; Chambers, A.F. Serial plasma osteopontin levels have prognostic value in metastatic breast cancer. Clin. Cancer Res. 2006, 12, 3337-3343.
-
(2006)
Clin. Cancer Res
, vol.12
, pp. 3337-3343
-
-
Bramwell, V.H.1
Doig, G.S.2
Tuck, A.B.3
Wilson, S.M.4
Tonkin, K.S.5
Tomiak, A.6
Perera, F.7
Vandenberg, T.A.8
Chambers, A.F.9
-
36
-
-
34548047714
-
Elevated circulating level of osteopontin is associated with advanced disease state of non-small cell lung cancer
-
Chang, Y.S.; Kim, H.J.; Chang, J.; Ahn, CM.; Kim, S.K. Elevated circulating level of osteopontin is associated with advanced disease state of non-small cell lung cancer. Lung Cancer 2007, 57, 373-380.
-
(2007)
Lung Cancer
, vol.57
, pp. 373-380
-
-
Chang, Y.S.1
Kim, H.J.2
Chang, J.3
Ahn, C.M.4
Kim, S.K.5
-
37
-
-
0036005977
-
Osteopontin modulates prostate carcinoma invasive capacity through rgd-dependent upregulation of plasminogen activators
-
Angelucci, A.; Festuccia, C; D’Andrea, G; Teti, A.; Bologna, M. Osteopontin modulates prostate carcinoma invasive capacity through rgd-dependent upregulation of plasminogen activators. Biol Chem. 2002, 383, 229-234.
-
(2002)
Biol Chem
, vol.383
, pp. 229-234
-
-
Angelucci, A.1
Festuccia, C.2
D’Andrea, G.3
Teti, A.4
Bologna, M.5
-
38
-
-
0141542626
-
Beta(3) integrin expression increases breast carcinoma cell responsiveness to the malignancy-enhancing effects of osteopontin
-
Furger, K.A.; Allan, A.L.; Wilson, S.M.; Hota, C; Vantyghem, S.A.; Postenka, CO.; Al-Katib, W.; Chambers, A.F.; Tuck, A.B. Beta(3) integrin expression increases breast carcinoma cell responsiveness to the malignancy-enhancing effects of osteopontin. Mol. Cancer Res. 2003, 1, 810-819.
-
(2003)
Mol. Cancer Res
, vol.1
, pp. 810-819
-
-
Furger, K.A.1
Allan, A.L.2
Wilson, S.M.3
Hota, C.4
Vantyghem, S.A.5
Postenka, C.O.6
Al-Katib, W.7
Chambers, A.F.8
Tuck, A.B.9
-
39
-
-
0030575895
-
Cell migration promoted by a potent grgds-containing thrombin-cleavage fragment of osteopontin
-
Senger, D.R.; Perruzzi, C.A. Cell migration promoted by a potent grgds-containing thrombin-cleavage fragment of osteopontin. Biochim. Biophys. Acta 1996, 1314, 13-24.
-
(1996)
Biochim. Biophys. Acta
, vol.1314
, pp. 13-24
-
-
Senger, D.R.1
Perruzzi, C.A.2
-
40
-
-
69249235848
-
Osteopontin increases migration and MMP-9 up-regulation via alphavbeta3 integrin, FAK, ERK, and NF-kappaB-dependent pathway in human chondrosarcoma cells
-
Chen, Y.J.; Wei, Y.Y.; Chen, H.T.; Fong, Y.C.; Hsu, C.J.; Tsai, C.H.; Hsu, H.C; Liu, S.H.; Tang, C.H. Osteopontin increases migration and MMP-9 up-regulation via alphavbeta3 integrin, FAK, ERK, and NF-kappaB-dependent pathway in human chondrosarcoma cells. J. Cell Physiol. 2009, 221, 98-108.
-
(2009)
J. Cell Physiol
, vol.221
, pp. 98-108
-
-
Chen, Y.J.1
Wei, Y.Y.2
Chen, H.T.3
Fong, Y.C.4
Hsu, C.J.5
Tsai, C.H.6
Hsu, H.C.7
Liu, S.H.8
Tang, C.H.9
-
41
-
-
0032535999
-
Cancer treatment by targeted drug delivery to tumor vasculature in a mouse model
-
Arap, W.; Pasqualini, R.; Ruoslahti, E. Cancer treatment by targeted drug delivery to tumor vasculature in a mouse model. Science 1998, 279, 377-380.
-
(1998)
Science
, vol.279
, pp. 377-380
-
-
Arap, W.1
Pasqualini, R.2
Ruoslahti, E.3
-
42
-
-
0033847194
-
RGD-dependent vacuolation and lumen formation observed during endothelial cell morphogenesis in three-dimensional fibrin matrices involves the αvβ3 and α5β1 integrins
-
Bayless, K.J.; Salazar, R.; Davis, G.E. RGD-dependent vacuolation and lumen formation observed during endothelial cell morphogenesis in three-dimensional fibrin matrices involves the αvβ3 and α5β1 integrins. Am. J. Pathol. 2000, 156, 1673-1683.
-
(2000)
Am. J. Pathol
, vol.156
, pp. 1673-1683
-
-
Bayless, K.J.1
Salazar, R.2
Davis, G.E.3
-
43
-
-
0028670833
-
Integrin alpha v beta 3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels
-
Brooks, P.C; Montgomery, A.M.; Rosenfeld, M.; Reisfeld, R.A.; Hu, T.; Klier, G; Cheresh, D.A. Integrin alpha v beta 3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels. Cell 1994, 79, 1157-1164.
-
(1994)
Cell
, vol.79
, pp. 1157-1164
-
-
Brooks, P.C.1
Montgomery, A.M.2
Rosenfeld, M.3
Reisfeld, R.A.4
Hu, T.5
Klier, G.6
Cheresh, D.A.7
-
44
-
-
0031596991
-
NF-kappaB mediates αvβ3 integrin-induced endothelial cell survival
-
Scatena, M.; Almeida, M.; Chaisson, M.L.; Fausto, N.; Nicosia, R.F.; Giachelli, CM. NF-kappaB mediates αvβ3 integrin-induced endothelial cell survival. J. Cell Biol. 1998, 141, 1083-1093.
-
(1998)
J. Cell Biol
, vol.141
, pp. 1083-1093
-
-
Scatena, M.1
Almeida, M.2
Chaisson, M.L.3
Fausto, N.4
Nicosia, R.F.5
Giachelli, C.M.6
-
45
-
-
0029999603
-
Stimulation of endothelial cell migration by vascular permeability factor/vascular endothelial growth factor through cooperative mechanisms involving the αvβ3 integrin, osteopontin, and thrombin
-
Senger, D.R; Ledbetter, S.R; Claffey, K.P.; Papadopoulos-Sergiou, A.; Peruzzi, C.A.; Detmar, M. Stimulation of endothelial cell migration by vascular permeability factor/vascular endothelial growth factor through cooperative mechanisms involving the αvβ3 integrin, osteopontin, and thrombin. Am. J. Pathol. 1996, 149, 293-305.
-
(1996)
Am. J. Pathol.
, vol.149
, pp. 293-305
-
-
Senger, D.R.1
Ledbetter, S.R.2
Claffey, K.P.3
Papadopoulos-Sergiou, A.4
Peruzzi, C.A.5
Detmar, M.6
-
46
-
-
18144451249
-
In vivo induction of insulin-like growth factor-I receptor and CD44V6 confers homing and adhesion to murine multiple myeloma cells
-
Asosingh, K.; Gunthert, U.; Bakkus, M.H.; de Raeve, H.; Goes, E.; van Riet, I.; van Camp, B.; Vanderkerken, K. In vivo induction of insulin-like growth factor-I receptor and CD44V6 confers homing and adhesion to murine multiple myeloma cells. Cancer Res. 2000, 60, 3096–3104.
-
(2000)
Cancer Res
, vol.60
, pp. 3096-3104
-
-
Asosingh, K.1
Gunthert, U.2
Bakkus, M.H.3
De Raeve, H.4
Goes, E.5
Van Riet, I.6
Van Camp, B.7
Vanderkerken, K.8
-
47
-
-
0032768970
-
CD44 cell adhesion molecules
-
Goodison, S.; Urquidi, V.; Tarin, D. CD44 cell adhesion molecules. Mol. Pathol. 1999, 52, 189–196.
-
(1999)
Mol. Pathol
, vol.52
, pp. 189-196
-
-
Goodison, S.1
Urquidi, V.2
Tarin, D.3
-
48
-
-
0025825209
-
A new variant of glycoprotein CD44 confers metastatic potential to rat carcinoma cells
-
Gunthert, U.; Hofmann, M.; Rudy, W.; Reber, S.; Zoller, M.; Haussmann, I.; Matzku, S.; Wenzel, A.; Ponta, H.; Herrlich, P. A new variant of glycoprotein CD44 confers metastatic potential to rat carcinoma cells. Cell 1991, 65, 13–24.
-
(1991)
Cell
, vol.65
, pp. 13-24
-
-
Gunthert, U.1
Hofmann, M.2
Rudy, W.3
Reber, S.4
Zoller, M.5
Haussmann, I.6
Matzku, S.7
Wenzel, A.8
Ponta, H.9
Herrlich, P.10
-
49
-
-
0037227965
-
CD44: From adhesion molecules to signalling regulators
-
Ponta, H.; Sherman, L.; Herrlich, P.A. CD44: From adhesion molecules to signalling regulators. Nat. Rev. Mol. Cell Biol. 2003, 4, 33–45.
-
(2003)
Nat. Rev. Mol. Cell Biol
, vol.4
, pp. 33-45
-
-
Ponta, H.1
Sherman, L.2
Herrlich, P.A.3
-
50
-
-
0030690285
-
CD44 and the adhesion of neoplastic cells
-
Rudzki, Z.; Jothy, S. CD44 and the adhesion of neoplastic cells. Mol. Pathol. 1997, 50, 57–71.
-
(1997)
Mol. Pathol
, vol.50
, pp. 57-71
-
-
Rudzki, Z.1
Jothy, S.2
-
51
-
-
0038505595
-
Restoration of CD44S in non-small cell lung cancer cells enhanced their susceptibility to the macrophage cytotoxicity
-
Takahashi, K.; Takahashi, F.; Hirama, M.; Tanabe, K.K.; Fukuchi, Y. Restoration of CD44S in non-small cell lung cancer cells enhanced their susceptibility to the macrophage cytotoxicity. Lung Cancer 2003, 41, 145–153.
-
(2003)
Lung Cancer
, vol.41
, pp. 145-153
-
-
Takahashi, K.1
Takahashi, F.2
Hirama, M.3
Tanabe, K.K.4
Fukuchi, Y.5
-
52
-
-
84907061567
-
Osteopontin shapes immunosuppression in the metastatic niche
-
Sangaletti, S.; Tripodo, C.; Sandri, S.; Torselli, I.; Vitali, C.; Ratti, C.; Botti, L.; Burocchi, A.; Porcasi, R.; Tomirotti, A.; et al. Osteopontin shapes immunosuppression in the metastatic niche. Cancer Res. 2014, 74, 4706–4719.
-
(2014)
Cancer Res
, vol.74
, pp. 4706-4719
-
-
Sangaletti, S.1
Tripodo, C.2
Sandri, S.3
Torselli, I.4
Vitali, C.5
Ratti, C.6
Botti, L.7
Burocchi, A.8
Porcasi, R.9
Tomirotti, A.10
-
53
-
-
34547606042
-
Functional atlas of the integrin adhesome
-
Zaidel-Bar, R.; Itzkovitz, S.; Ma’ayan, A.; Iyengar, R.; Geiger, B. Functional atlas of the integrin adhesome. Nat. Cell Biol. 2007, 9, 858–867.
-
(2007)
Nat. Cell Biol
, vol.9
, pp. 858-867
-
-
Zaidel-Bar, R.1
Itzkovitz, S.2
Ma’Ayan, A.3
Iyengar, R.4
Geiger, B.5
-
54
-
-
0141625303
-
Structure of integrin alpha5beta1 in complex with fibronectin
-
Takagi, J.; Strokovich, K.; Springer, T.A.; Walz, T. Structure of integrin alpha5beta1 in complex with fibronectin. Embo J. 2003, 22, 4607–4615.
-
(2003)
Embo J
, vol.22
, pp. 4607-4615
-
-
Takagi, J.1
Strokovich, K.2
Springer, T.A.3
Walz, T.4
-
57
-
-
11344267803
-
Prostate cancer bone metastases promote both osteolytic and osteoblastic activity
-
Keller, E.T.; Brown, J. Prostate cancer bone metastases promote both osteolytic and osteoblastic activity. J. Cell Biochem. 2004, 91, 718–729.
-
(2004)
J. Cell Biochem
, vol.91
, pp. 718-729
-
-
Keller, E.T.1
Brown, J.2
-
58
-
-
84878783165
-
Integrins and metastasis
-
Ganguly, K.K.; Pal, S.; Moulik, S.; Chatterjee, A. Integrins and metastasis. Cell Adh. Migr. 2013, 7, 251–261.
-
(2013)
Cell Adh. Migr
, vol.7
, pp. 251-261
-
-
Ganguly, K.K.1
Pal, S.2
Moulik, S.3
Chatterjee, A.4
-
59
-
-
18844469913
-
Expression of integrin alphavbeta3 in pancreatic carcinoma: Relation to MMP-2 activation and lymph node metastasis
-
Hosotani, R.; Kawaguchi, M.; Masui, T.; Koshiba, T.; Ida, J.; Fujimoto, K.; Wada, M.; Doi, R.; Imamura, M. Expression of integrin alphavbeta3 in pancreatic carcinoma: Relation to MMP-2 activation and lymph node metastasis. Pancreas 2002, 25, e30–e35.
-
(2002)
Pancreas
, vol.25
, pp. e30-e35
-
-
Hosotani, R.1
Kawaguchi, M.2
Masui, T.3
Koshiba, T.4
Ida, J.5
Fujimoto, K.6
Wada, M.7
Doi, R.8
Imamura, M.9
-
60
-
-
16344380043
-
The relationship between bone metastasis from human breast cancer and integrin alpha(v)beta3 expression
-
Takayama, S.; Ishii, S.; Ikeda, T.; Masamura, S.; Doi, M.; Kitajima, M. The relationship between bone metastasis from human breast cancer and integrin alpha(v)beta3 expression. Anticancer Res. 2005, 25, 79–83.
-
(2005)
Anticancer Res
, vol.25
, pp. 79-83
-
-
Takayama, S.1
Ishii, S.2
Ikeda, T.3
Masamura, S.4
Doi, M.5
Kitajima, M.6
-
61
-
-
60549101931
-
Specific cross-talk between epidermal growth factor receptor and integrin alphavbeta5 promotes carcinoma cell invasion and metastasis
-
Ricono, J.M.; Huang, M.; Barnes, L.A.; Lau, S.K.; Weis, S.M.; Schlaepfer, D.D.; Hanks, S.K.; Cheresh, D.A. Specific cross-talk between epidermal growth factor receptor and integrin alphavbeta5 promotes carcinoma cell invasion and metastasis. Cancer Res. 2009, 69, 1383–1391.
-
(2009)
Cancer Res
, vol.69
, pp. 1383-1391
-
-
Ricono, J.M.1
Huang, M.2
Barnes, L.A.3
Lau, S.K.4
Weis, S.M.5
Schlaepfer, D.D.6
Hanks, S.K.7
Cheresh, D.A.8
-
62
-
-
0037495268
-
Clinicopathological associations of CD44 mrna and protein expression in primary breast carcinomas
-
Berner, H.S.; Suo, Z.; Risberg, B.; Villman, K.; Karlsson, M.G.; Nesland, J.M. Clinicopathological associations of CD44 mrna and protein expression in primary breast carcinomas. Histopathology 2003, 42, 546–554.
-
(2003)
Histopathology
, vol.42
, pp. 546-554
-
-
Berner, H.S.1
Suo, Z.2
Risberg, B.3
Villman, K.4
Karlsson, M.G.5
Nesland, J.M.6
-
63
-
-
18244387224
-
CD44 expression is associated with increased survival in node-negative invasive breast carcinoma
-
Diaz, L.K.; Zhou, X.; Wright, E.T.; Cristofanilli, M.; Smith, T.; Yang, Y.; Sneige, N.; Sahin, A.; Gilcrease, M.Z. CD44 expression is associated with increased survival in node-negative invasive breast carcinoma. Clin. Cancer Res. 2005, 11, 3309–3314.
-
(2005)
Clin. Cancer Res
, vol.11
, pp. 3309-3314
-
-
Diaz, L.K.1
Zhou, X.2
Wright, E.T.3
Cristofanilli, M.4
Smith, T.5
Yang, Y.6
Sneige, N.7
Sahin, A.8
Gilcrease, M.Z.9
-
64
-
-
1242285621
-
The role of CD44V3 expression in female breast carcinomas
-
Rys, J.; Kruczak, A.; Lackowska, B.; Jaszcz-Gruchala, A.; Brandys, A.; Stelmach, A.; Reinfuss, M. The role of CD44V3 expression in female breast carcinomas. Pol. J. Pathol. 2003, 54, 243–247.
-
(2003)
Pol. J. Pathol
, vol.54
, pp. 243-247
-
-
Rys, J.1
Kruczak, A.2
Lackowska, B.3
Jaszcz-Gruchala, A.4
Brandys, A.5
Stelmach, A.6
Reinfuss, M.7
-
65
-
-
84866984809
-
Overexpression of CD44 accompanies acquired tamoxifen resistance in MCF7 cells and augments their sensitivity to the stromal factors, heregulin and hyaluronan
-
Hiscox, S.; Baruha, B.; Smith, C.; Bellerby, R.; Goddard, L.; Jordan, N.; Poghosyan, Z.; Nicholson, R.I.; Barrett-Lee, P.; Gee, J. Overexpression of CD44 accompanies acquired tamoxifen resistance in MCF7 cells and augments their sensitivity to the stromal factors, heregulin and hyaluronan. BMC Cancer 2012, doi:10.1186/1471-2407-1112-1458.
-
(2012)
BMC Cancer
-
-
Hiscox, S.1
Baruha, B.2
Smith, C.3
Bellerby, R.4
Goddard, L.5
Jordan, N.6
Poghosyan, Z.7
Nicholson, R.I.8
Barrett-Lee, P.9
Gee, J.10
-
66
-
-
77954196772
-
Human ovarian cancer stem cells
-
Bapat, S.A. Human ovarian cancer stem cells. Reproduction 2010, 140, 33–41.
-
(2010)
Reproduction
, vol.140
, pp. 33-41
-
-
Bapat, S.A.1
-
67
-
-
58149269566
-
CD44 is of functional importance for colorectal cancer stem cells
-
Du, L.; Wang, H.; He, L.; Zhang, J.; Ni, B.; Wang, X.; Jin, H.; Cahuzac, N.; Mehrpour, M.; Lu, Y.; Chen, Q. CD44 is of functional importance for colorectal cancer stem cells. Clin. Cancer Res. 2008, 14, 6751–6760.
-
(2008)
Clin. Cancer Res
, vol.14
, pp. 6751-6760
-
-
Du, L.1
Wang, H.2
He, L.3
Zhang, J.4
Ni, B.5
Wang, X.6
Jin, H.7
Cahuzac, N.8
Mehrpour, M.9
Lu, Y.10
Chen, Q.11
-
68
-
-
84862286978
-
Significance of CD44 and CD24 as cancer stem cell markers: An enduring ambiguity
-
Jaggupilli, A.; Elkord, E. Significance of CD44 and CD24 as cancer stem cell markers: An enduring ambiguity. Clin. Dev. Immunol. 2012, doi:10.1155/2012/708036.
-
(2012)
Clin. Dev. Immunol
-
-
Jaggupilli, A.1
Elkord, E.2
-
69
-
-
84904868672
-
Comparison of mammosphere formation from breast cancer cell lines and primary breast tumors
-
Wang, R.; Lv, Q.; Meng, W.; Tan, Q.; Zhang, S.; Mo, X.; Yang, X. Comparison of mammosphere formation from breast cancer cell lines and primary breast tumors. J. Thorac. Dis. 2014, 6, 829–837.
-
(2014)
J. Thorac. Dis.
, vol.6
, pp. 829-837
-
-
Wang, R.1
Lv, Q.2
Meng, W.3
Tan, Q.4
Zhang, S.5
Mo, X.6
Yang, X.7
-
70
-
-
33847770211
-
TGF-beta signaling in breast cancer
-
Buck, M.B.; Knabbe, C. TGF-beta signaling in breast cancer. Ann. N. Y. Acad. Sci. 2006, 1089, 119–126.
-
(2006)
Ann. N. Y. Acad. Sci
, vol.1089
, pp. 119-126
-
-
Buck, M.B.1
Knabbe, C.2
-
71
-
-
84859443358
-
Non-smad signaling pathways
-
Mu, Y.; Gudey, S.K.; Landstrom, M. Non-smad signaling pathways. Cell Tissue Res. 2012, 347, 11–20.
-
(2012)
Cell Tissue Res
, vol.347
, pp. 11-20
-
-
Mu, Y.1
Gudey, S.K.2
Landstrom, M.3
-
72
-
-
27844478189
-
TGFbeta-induced downregulation of E-cadherin-based cell-cell adhesion depends on PI3-kinase and pten
-
Vogelmann, R.; Nguyen-Tat, M.D.; Giehl, K.; Adler, G.; Wedlich, D.; Menke, A. TGFbeta-induced downregulation of E-cadherin-based cell-cell adhesion depends on PI3-kinase and pten. J. Cell Sci. 2005, 118, 4901–4912.
-
(2005)
J. Cell Sci
, vol.118
, pp. 4901-4912
-
-
Vogelmann, R.1
Nguyen-Tat, M.D.2
Giehl, K.3
Adler, G.4
Wedlich, D.5
Menke, A.6
-
73
-
-
0031933224
-
Molecular and cell biology of TGF-beta
-
Roberts, A.B. Molecular and cell biology of TGF-beta. Miner. Electrolyte MeTable 1998, 24, 111–119.
-
(1998)
Miner. Electrolyte Metable
, vol.24
, pp. 111-119
-
-
Roberts, A.B.1
-
74
-
-
47549090432
-
TGFbeta in cancer
-
Massague, J. TGFbeta in cancer. Cell 2008, 134, 215–230.
-
(2008)
Cell
, vol.134
, pp. 215-230
-
-
Massague, J.1
-
75
-
-
74949093198
-
Transforming growth factor-beta signaling in epithelial-mesenchymal transition and progression of Cancer
-
Miyazono, K. Transforming growth factor-beta signaling in epithelial-mesenchymal transition and progression of Cancer. Proc. Jpn. Acad. B Phys. Biol. Sci. 2009, 85, 314–323.
-
(2009)
Proc. Jpn. Acad. B Phys. Biol. Sci
, vol.85
, pp. 314-323
-
-
Miyazono, K.1
-
76
-
-
59449090107
-
TGF-beta-induced epithelial to mesenchymal transition
-
Xu, J.; Lamouille, S.; Derynck, R. TGF-beta-induced epithelial to mesenchymal transition. Cell Res. 2009, 19, 156–172.
-
(2009)
Cellres
, vol.19
, pp. 156-172
-
-
Xu, J.1
Lamouille, S.2
Derynck, R.3
-
77
-
-
41049094560
-
Endoglin in angiogenesis and vascular diseases
-
ten Dijke, P.; Goumans, M.J.; Pardali, E. Endoglin in angiogenesis and vascular diseases. Angiogenesis. 2008, 11, 79–89.
-
(2008)
Angiogenesis
, vol.11
, pp. 79-89
-
-
Ten Dijke, P.1
Goumans, M.J.2
Pardali, E.3
-
78
-
-
79959526395
-
TGF-beta signaling in breast cancer cell invasion and bone metastasis
-
Drabsch, Y.; ten Dijke, P. TGF-beta signaling in breast cancer cell invasion and bone metastasis. J. Mammary Gland Biol. Neoplasia 2011, 16, 97–108.
-
(2011)
J. Mammary Gland Biol. Neoplasia
, vol.16
, pp. 97-108
-
-
Drabsch, Y.1
Ten Dijke, P.2
-
79
-
-
77954951446
-
The polarization of immune cells in the tumour environment by TGFbeta
-
Flavell, R.A.; Sanjabi, S.; Wrzesinski, S.H.; Licona-Limon, P. The polarization of immune cells in the tumour environment by TGFbeta. Nat. Rev. Immunol. 2010, 10, 554–567.
-
(2010)
Nat. Rev. Immunol
, vol.10
, pp. 554-567
-
-
Flavell, R.A.1
Sanjabi, S.2
Wrzesinski, S.H.3
Licona-Limon, P.4
-
80
-
-
79551647444
-
Switching TGFbeta from a tumor suppressor to a tumor promoter
-
Inman, G.J. Switching TGFbeta from a tumor suppressor to a tumor promoter. Curr. Opin. Genet. Dev. 2011, 21, 93–99.
-
(2011)
Curr. Opin. Genet. Dev
, vol.21
, pp. 93-99
-
-
Inman, G.J.1
-
81
-
-
84893867951
-
TGF-beta: Duality of function between tumor prevention and carcinogenesis
-
Principe, D.R.; Doll, J.A.; Bauer, J.; Jung, B.; Munshi, H.G.; Bartholin, L.; Pasche, B.; Lee, C.; Grippo, P.J. TGF-beta: Duality of function between tumor prevention and carcinogenesis. J. Natl. Cancer Inst. 2014, doi:10.1093/jnci/djt1369.
-
(2014)
J. Natl. Cancer Inst
-
-
Principe, D.R.1
Doll, J.A.2
Bauer, J.3
Jung, B.4
Munshi, H.G.5
Bartholin, L.6
Pasche, B.7
Lee, C.8
Grippo, P.J.9
-
82
-
-
84887138387
-
The relevance of the TGF-beta paradox to EMT-MET programs
-
Morrison, CD.; Parvani, J.G.; Schiemann, W.P. The relevance of the TGF-beta paradox to EMT-MET programs. Cancer Lett. 2013, 341, 30-40.
-
(2013)
Cancer Lett
, vol.341
, pp. 30-40
-
-
Morrison, C.D.1
Parvani, J.G.2
Schiemann, W.P.3
-
83
-
-
84904597693
-
Mysteries of TGF-beta paradox in benign and malignant cells
-
Zhang, Q.; Yu, N.; Lee, C. Mysteries of TGF-beta paradox in benign and malignant cells. Front. Oncol. 2014, doi:10.3389/fonc.2014.00094.
-
(2014)
Front. Oncol
-
-
Zhang, Q.1
Yu, N.2
Lee, C.3
-
84
-
-
84921914995
-
Vicious cycle of TGF-beta signaling in tumor progression and metastasis
-
Zhang, Q.; Yu, N.; Lee, C. Vicious cycle of TGF-beta signaling in tumor progression and metastasis. Am. J. Clin. Exp. Urol. 2014, 2, 149-155.
-
(2014)
Am. J. Clin. Exp. Urol.
, vol.2
, pp. 149-155
-
-
Zhang, Q.1
Yu, N.2
Lee, C.3
-
85
-
-
33746078098
-
“To erb-b or not to erb-b…” Neuregulin-1/erbb signaling in heart development and function
-
Garratt, A.N. “To erb-b or not to erb-b…” Neuregulin-1/erbb signaling in heart development and function. J. Mol. Cell Cardiol. 2006, 41, 215-218.
-
(2006)
J. Mol. Cell Cardiol.
, vol.41
, pp. 215-218
-
-
Garratt, A.N.1
-
86
-
-
0030911331
-
Ligands for erbb-family receptors encoded by a neuregulin-like gene
-
Chang, H.; Riese, D.J., 2nd; Gilbert, W.; Stern, D.F.; McMahan, U.J. Ligands for erbb-family receptors encoded by a neuregulin-like gene. Nature 1997, 387, 509-512.
-
(1997)
Nature
, vol.387
, pp. 509-512
-
-
Chang, H.1
Riese, D.J.2
Gilbert, W.3
Stern, D.F.4
McMahan, U.J.5
-
87
-
-
0033614356
-
Neuregulin-4: A novel growth factor that acts through the ErbB-4 receptor tyrosine kinase
-
Harari, D.; Tzahar, E.; Romano, J.; Shelly, M.; Pierce, J.H.; Andrews, G.C.; Yarden, Y. Neuregulin-4: A novel growth factor that acts through the ErbB-4 receptor tyrosine kinase. Oncogene 1999, 18, 2681-2689.
-
(1999)
Oncogene
, vol.18
, pp. 2681-2689
-
-
Harari, D.1
Tzahar, E.2
Romano, J.3
Shelly, M.4
Pierce, J.H.5
Andrews, G.C.6
Yarden, Y.7
-
88
-
-
0026659262
-
Identification of heregulin, a specific activator of p185erbb2
-
Holmes, W.E.; Sliwkowski, M.X.; Akita, R.W.; Henzel, W.J.; Lee, J.; Park, J.W.; Yansura, D.; Abadi, N.; Raab, H.; Lewis, G.D. et al. Identification of heregulin, a specific activator of p185erbb2. Science 1992, 256, 1205-1210.
-
(1992)
Science
, vol.256
, pp. 1205-1210
-
-
Holmes, W.E.1
Sliwkowski, M.X.2
Akita, R.W.3
Henzel, W.J.4
Lee, J.5
Park, J.W.6
Yansura, D.7
Abadi, N.8
Raab, H.9
Lewis, G.D.10
-
89
-
-
12644279865
-
Neuregulin-3 (NRG3): A novel neural tissue-enriched protein that binds and activates ErbB4
-
Zhang, D.; Sliwkowski, M.X.; Mark, M.; Frantz, G; Akita, R.; Sun, Y.; Hillan, K.; Crowley, C; Brush, J.; Godowski, P.J. Neuregulin-3 (NRG3): A novel neural tissue-enriched protein that binds and activates ErbB4. Proc. Natl. Acad. Sci. USA 1997, 94, 9562-9567.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 9562-9567
-
-
Zhang, D.1
Sliwkowski, M.X.2
Mark, M.3
Frantz, G.4
Akita, R.5
Sun, Y.6
Hillan, K.7
Crowley, C.8
Brush, J.9
Godowski, P.J.10
-
90
-
-
0028335209
-
The ErbB3 gene product is a receptor for heregulin
-
Carraway, K.L., 3rd; Sliwkowski, M.X.; Akita, R.; Platko, J.V.; Guy, P.M.; Nuijens, A.; Diamonti, A.J.; Vandlen, R.L.; Cantley, L.C.; Cerione, R.A. The ErbB3 gene product is a receptor for heregulin. J. Biol. Chem. 1994, 269, 14303-14306.
-
(1994)
J. Biol. Chem
, vol.269
, pp. 14303-14306
-
-
Carraway, K.L.1
Sliwkowski, M.X.2
Akita, R.3
Platko, J.V.4
Guy, P.M.5
Nuijens, A.6
Diamonti, A.J.7
Vandlen, R.L.8
Cantley, L.C.9
Cerione, R.A.10
-
91
-
-
19944404432
-
Roles for neuregulins in human Cancer
-
Stove, C; Bracke, M. Roles for neuregulins in human Cancer. Clin. Exp. Metastasis. 2004, 21, 665-684.
-
(2004)
Clin. Exp. Metastasis
, vol.21
, pp. 665-684
-
-
Stove, C.1
Bracke, M.2
-
92
-
-
33745155000
-
Neuregulins: Versatile growth and differentiation factors in nervous system development and human disease
-
Esper, R.M.; Pankonin, M.S.; Loeb, J.A. Neuregulins: Versatile growth and differentiation factors in nervous system development and human disease. Brain Res. Rev. 2006, 51, 161-175.
-
(2006)
Brain Res. Rev
, vol.51
, pp. 161-175
-
-
Esper, R.M.1
Pankonin, M.S.2
Loeb, J.A.3
-
93
-
-
3042668916
-
Neuregulins and the neuromuscular system: 10 years of answers and questions
-
Falls, D.L. Neuregulins and the neuromuscular system: 10 years of answers and questions. J. Neurocytol. 2003, 32, 619-647.
-
(2003)
J. Neurocytol
, vol.32
, pp. 619-647
-
-
Falls, D.L.1
-
94
-
-
0037173740
-
The breast proto-oncogene, hrgalpha regulates epithelial proliferation and lobuloalveolar development in the mouse mammary gland
-
Li, L.; Cleary, S.; Mandarano, M.A.; Long, W.; Birchmeier, C; Jones, F.E. The breast proto-oncogene, hrgalpha regulates epithelial proliferation and lobuloalveolar development in the mouse mammary gland. Oncogene 2002, 21, 4900-4907.
-
(2002)
Oncogene
, vol.21
, pp. 4900-4907
-
-
Li, L.1
Cleary, S.2
Mandarano, M.A.3
Long, W.4
Birchmeier, C.5
Jones, F.E.6
-
95
-
-
33747377549
-
Trastuzumab in combination with heregulin-activated Her-2 (ErbB-2) triggers a receptor-enhanced chemosensitivity effect in the absence of Her-2 overexpression
-
Menendez, J.A.; Mehmi, I.; Lupu, R. Trastuzumab in combination with heregulin-activated Her-2 (ErbB-2) triggers a receptor-enhanced chemosensitivity effect in the absence of Her-2 overexpression. J. Clin. Oncol. 2006, 24, 3735-3746.
-
(2006)
J. Clin. Oncol
, vol.24
, pp. 3735-3746
-
-
Menendez, J.A.1
Mehmi, I.2
Lupu, R.3
-
96
-
-
0035141107
-
Neuregulin 1-alpha expression in locally advanced breast cancer
-
Raj, E.H.; Skinner, A.; Mahji, U.; Nirmala, K.N.; Ravichandran, K.; Shanta, V.; Hurst, H.C.; Gullick, W.J.; Rajkumar, T. Neuregulin 1-alpha expression in locally advanced breast cancer. Breast (Edinburgh, Scotland) 2001, 10, 41-45.
-
(2001)
Breast (Edinburgh, Scotland)
, vol.10
, pp. 41-45
-
-
Raj, E.H.1
Skinner, A.2
Mahji, U.3
Nirmala, K.N.4
Ravichandran, K.5
Shanta, V.6
Hurst, H.C.7
Gullick, W.J.8
Rajkumar, T.9
-
97
-
-
67349184448
-
Heregulin-beta1 promotes metastasis of breast cancer cell line SKBR3 through upregulation of snail and induction of epithelial-mesenchymal transition
-
Cheng, L.; Zha, Z.; Lang, B.; Liu, J.; Yao, X. Heregulin-beta1 promotes metastasis of breast cancer cell line SKBR3 through upregulation of snail and induction of epithelial-mesenchymal transition. Cancer Lett. 2009, 280, 50-60.
-
(2009)
Cancer Lett
, vol.280
, pp. 50-60
-
-
Cheng, L.1
Zha, Z.2
Lang, B.3
Liu, J.4
Yao, X.5
-
98
-
-
84881128429
-
HRG-beta1-driven ErbB3 signaling induces epithelial-mesenchymal transition in breast cancer cells
-
Kim, J.; Jeong, H.; Lee, Y.; Kim, C; Kim, H.; Kim, A. HRG-beta1-driven ErbB3 signaling induces epithelial-mesenchymal transition in breast cancer cells. BMC Cancer 2013, 13, 383.
-
(2013)
BMC Cancer
, vol.13
, pp. 383
-
-
Kim, J.1
Jeong, H.2
Lee, Y.3
Kim, C.4
Kim, H.5
Kim, A.6
-
99
-
-
0032561206
-
Heregulin regulates cytoskeletal reorganization and cell migration through the p21-activated kinase-1 via phosphatidylinositol-3 kinase
-
Adam, L.; Vadlamudi, R.; Kondapaka, S.B.; Chernoff, J.; Mendelsohn, J.; Kumar, R. Heregulin regulates cytoskeletal reorganization and cell migration through the p21-activated kinase-1 via phosphatidylinositol-3 kinase. J. Biol. Chem. 1998, 273, 28238–28246.
-
(1998)
J. Biol. Chem
, vol.273
, pp. 28238-28246
-
-
Adam, L.1
Vadlamudi, R.2
Kondapaka, S.B.3
Chernoff, J.4
Mendelsohn, J.5
Kumar, R.6
-
100
-
-
0034650658
-
Heregulin regulation of autocrine motility factor expression in human tumor cells
-
Talukder, A.H.; Adam, L.; Raz, A.; Kumar, R. Heregulin regulation of autocrine motility factor expression in human tumor cells. Cancer Res. 2000, 60, 474–480.
-
(2000)
Cancer Res
, vol.60
, pp. 474-480
-
-
Talukder, A.H.1
Adam, L.2
Raz, A.3
Kumar, R.4
-
101
-
-
0034045040
-
Histone deacetylases, transcriptional control, and cancer
-
Cress, W.D.; Seto, E. Histone deacetylases, transcriptional control, and cancer J. Cell Physiol. 2000, 184, 1–16.
-
(2000)
J. Cell Physiol
, vol.184
, pp. 1-16
-
-
Cress, W.D.1
Seto, E.2
-
102
-
-
0029003375
-
Aria can be released from extracellular matrix through cleavage of a heparin-binding domain
-
Loeb, J.A.; Fischbach, G.D. Aria can be released from extracellular matrix through cleavage of a heparin-binding domain. J. Cell Biol. 1995, 130, 127–135.
-
(1995)
J. Cell Biol
, vol.130
, pp. 127-135
-
-
Loeb, J.A.1
Fischbach, G.D.2
-
103
-
-
0037291769
-
EGF activates its receptor by removing interactions that autoinhibit ectodomain dimerization
-
Ferguson, K.M.; Berger, M.B.; Mendrola, J.M.; Cho, H.S.; Leahy, D.J.; Lemmon, M.A. EGF activates its receptor by removing interactions that autoinhibit ectodomain dimerization. Mol. Cell 2003, 11, 507–517.
-
(2003)
Mol. Cell
, vol.11
, pp. 507-517
-
-
Ferguson, K.M.1
Berger, M.B.2
Mendrola, J.M.3
Cho, H.S.4
Leahy, D.J.5
Lemmon, M.A.6
-
105
-
-
0030974096
-
Neuregulin-2, a new ligand of ErbB3/ErbB4-receptor tyrosine kinases
-
Carraway, K.L., 3rd; Weber, J.L.; Unger, M.J.; Ledesma, J.; Yu, N.; Gassmann, M.; Lai, C. Neuregulin-2, a new ligand of ErbB3/ErbB4-receptor tyrosine kinases. Nature 1997, 387, 512–516.
-
(1997)
Nature
, vol.387
, pp. 512-516
-
-
Carraway, K.L.1
Weber, J.L.2
Unger, M.J.3
Ledesma, J.4
Yu, N.5
Gassmann, M.6
Lai, C.7
-
106
-
-
18344390418
-
ErbB receptors and cancer: The complexity of targeted inhibitors
-
Hynes, N.E.; Lane, H.A. ErbB receptors and cancer: The complexity of targeted inhibitors. Nat. Rev. Cancer 2005, 5, 341–354.
-
(2005)
Nat. Rev. Cancer
, vol.5
, pp. 341-354
-
-
Hynes, N.E.1
Lane, H.A.2
-
107
-
-
1842591231
-
Role of protein ubiquitylation in regulating endocytosis of receptor tyrosine kinases
-
Marmor, M.D.; Yarden, Y. Role of protein ubiquitylation in regulating endocytosis of receptor tyrosine kinases. Oncogene 2004, 23, 2057–2070.
-
(2004)
Oncogene
, vol.23
, pp. 2057-2070
-
-
Marmor, M.D.1
Yarden, Y.2
-
108
-
-
0036518996
-
Phosphotyrosine-binding domains in signal transduction
-
Yaffe, M.B. Phosphotyrosine-binding domains in signal transduction. Nat. Rev. Mol. Cell Biol. 2002, 3, 177–186.
-
(2002)
Nat. Rev. Mol. Cell Biol
, vol.3
, pp. 177-186
-
-
Yaffe, M.B.1
-
109
-
-
0037429722
-
ErbB-4: Mechanism of action and biology
-
Carpenter, G. ErbB-4: Mechanism of action and biology. Exp. Cell Res. 2003, 284, 66–77.
-
(2003)
Exp. Cell Res
, vol.284
, pp. 66-77
-
-
Carpenter, G.1
-
110
-
-
0037429779
-
The deaf and the dumb: The biology of ErbB-2 and ErbB-3
-
Citri, A.; Skaria, K.B.; Yarden, Y. The deaf and the dumb: The biology of ErbB-2 and ErbB-3. Exp. Cell Res. 2003, 284, 54–65.
-
(2003)
Exp. Cell Res
, vol.284
, pp. 54-65
-
-
Citri, A.1
Skaria, K.B.2
Yarden, Y.3
-
111
-
-
0037429737
-
Epidermal growth factor receptor: Mechanisms of activation and signalling
-
Jorissen, R.N.; Walker, F.; Pouliot, N.; Garrett, T.P.; Ward, C.W.; Burgess, A.W. Epidermal growth factor receptor: Mechanisms of activation and signalling. Exp. Cell Res. 2003, 284, 31–53.
-
(2003)
Exp. Cell Res
, vol.284
, pp. 31-53
-
-
Jorissen, R.N.1
Walker, F.2
Pouliot, N.3
Garrett, T.P.4
Ward, C.W.5
Burgess, A.W.6
-
112
-
-
0034722889
-
The EGF receptor family as targets for cancer therapy
-
Mendelsohn, J.; Baselga, J. The EGF receptor family as targets for cancer therapy. Oncogene 2000, 19, 6550–6565.
-
(2000)
Oncogene
, vol.19
, pp. 6550-6565
-
-
Mendelsohn, J.1
Baselga, J.2
-
113
-
-
0026548240
-
Structural alterations of the epidermal growth factor receptor gene in human gliomas
-
Wong, A.J.; Ruppert, J.M.; Bigner, S.H.; Grzeschik, C.H.; Humphrey, P.A.; Bigner, D.S.; Vogelstein, B. Structural alterations of the epidermal growth factor receptor gene in human gliomas. Proc. Natl. Acad. Sci. USA 1992, 89, 2965–2969.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 2965-2969
-
-
Wong, A.J.1
Ruppert, J.M.2
Bigner, S.H.3
Grzeschik, C.H.4
Humphrey, P.A.5
Bigner, D.S.6
Vogelstein, B.7
-
114
-
-
74549114727
-
Epidermal growth factor receptor in relation to tumor development
-
Mitsudomi, T.; Yatabe, Y. Epidermal growth factor receptor in relation to tumor development: EGFR gene and cancer. FEBS J. 2010, 277, 301–308.
-
(2010)
EGFR Gene and Cancer. FEBS J.
, vol.277
, pp. 301-308
-
-
Mitsudomi, T.1
Yatabe, Y.2
-
115
-
-
0031708626
-
Clinical relevance of transforming growth factor alpha, epidermal growth factor receptor, p53, and ki67 in colorectal liver metastases and corresponding primary tumors
-
De Jong, K.P.; Stellema, R.; Karrenbeld, A.; Koudstaal, J.; Gouw, A.S.; Sluiter, W.J.; Peeters, P.M.; Slooff, M.J.; de Vries, E.G. Clinical relevance of transforming growth factor alpha, epidermal growth factor receptor, p53, and ki67 in colorectal liver metastases and corresponding primary tumors. Hepatology 1998, 28, 971–979.
-
(1998)
Hepatology
, vol.28
, pp. 971-979
-
-
De Jong, K.P.1
Stellema, R.2
Karrenbeld, A.3
Koudstaal, J.4
Gouw, A.S.5
Sluiter, W.J.6
Peeters, P.M.7
Slooff, M.J.8
De Vries, E.G.9
-
116
-
-
0032988428
-
Activation of map kinases in growth responsive pancreatic cancer cells
-
Douziech, N.; Calvo, E.; Laine, J.; Morisset, J. Activation of map kinases in growth responsive pancreatic cancer cells. Cell Signal. 1999, 11, 591–602.
-
(1999)
Cell Signal
, vol.11
, pp. 591-602
-
-
Douziech, N.1
Calvo, E.2
Laine, J.3
Morisset, J.4
-
117
-
-
0034988184
-
The epidermal growth factor receptor as a target for cancer therapy. Endocr. Relat
-
Mendelsohn, J. The epidermal growth factor receptor as a target for cancer therapy. Endocr. Relat. Cancer 2001, 8, 3–9.
-
(2001)
Cancer
, vol.8
, pp. 3-9
-
-
Mendelsohn, J.1
-
118
-
-
84883155020
-
The role of epidermal growth factor receptor in cancer metastasis and microenvironment
-
Sasaki, T.; Hiroki, K.; Yamashita, Y. The role of epidermal growth factor receptor in cancer metastasis and microenvironment. Biomed. Res. Int. 2013, doi:10.1155/2013/546318.
-
(2013)
Biomed. Res. Int
-
-
Sasaki, T.1
Hiroki, K.2
Yamashita, Y.3
-
119
-
-
0029814271
-
A hierarchical network of interreceptor interactions determines signal transduction by Neu differentiation factor/neuregulin and epidermal growth factor
-
Tzahar, E.; Waterman, H.; Chen, X.; Levkowitz, G.; Karunagaran, D.; Lavi, S.; Ratzkin, B.J.; Yarden, Y. A hierarchical network of interreceptor interactions determines signal transduction by Neu differentiation factor/neuregulin and epidermal growth factor. Mol. Cell Biol. 1996, 16, 5276–5287.
-
(1996)
Mol. Cell Biol
, vol.16
, pp. 5276-5287
-
-
Tzahar, E.1
Waterman, H.2
Chen, X.3
Levkowitz, G.4
Karunagaran, D.5
Lavi, S.6
Ratzkin, B.J.7
Yarden, Y.8
-
120
-
-
0028354305
-
C-ErbB-2 expression and response to adjuvant therapy in women with node-positive early breast Cancer
-
Muss, H.B.; Thor, A.D.; Berry, D.A.; Kute, T.; Liu, E.T.; Koerner, F.; Cirrincione, C.T.; Budman, D.R.; Wood, W.C.; Barcos, M. et al. C-ErbB-2 expression and response to adjuvant therapy in women with node-positive early breast Cancer. N. Engl. J. Med. 1994, 330, 1260–1266.
-
(1994)
N. Engl. J. Med.
, vol.330
, pp. 1260-1266
-
-
Muss, H.B.1
Thor, A.D.2
Berry, D.A.3
Kute, T.4
Liu, E.T.5
Koerner, F.6
Cirrincione, C.T.7
Budman, D.R.8
Wood, W.C.9
Barcos, M.10
-
121
-
-
0024337144
-
Studies of the Her-2/NEU proto-oncogene in human breast and ovarian Cancer
-
Slamon, D.J.; Godolphin, W.; Jones, L.A.; Holt, J.A.; Wong, S.G.; Keith, D.E.; Levin, W.J.; Stuart, S.G.; Udove, J.; Ullrich, A. et al. Studies of the Her-2/NEU proto-oncogene in human breast and ovarian Cancer. Science 1989, 244, 707–712.
-
(1989)
Science
, vol.244
, pp. 707-712
-
-
Slamon, D.J.1
Godolphin, W.2
Jones, L.A.3
Holt, J.A.4
Wong, S.G.5
Keith, D.E.6
Levin, W.J.7
Stuart, S.G.8
Udove, J.9
Ullrich, A.10
-
122
-
-
0029812759
-
Polyubiquitination and proteasomal degradation of the p185c-ErbB-2 receptor protein-tyrosine kinase induced by geldanamycin
-
Mimnaugh, E.G.; Chavany, C.; Neckers, L. Polyubiquitination and proteasomal degradation of the p185c-ErbB-2 receptor protein-tyrosine kinase induced by geldanamycin. J. Biol. Chem. 1996, 271, 22796–22801.
-
(1996)
J. Biol. Chem
, vol.271
, pp. 22796-22801
-
-
Mimnaugh, E.G.1
Chavany, C.2
Neckers, L.3
-
123
-
-
0035793546
-
Sensitivityof mature ErbB2 to geldanamycin is conferred by its kinase domain and is mediated by the chaperone protein hsp90
-
Xu, W.; Mimnaugh, E.; Rosser, M.F.; Nicchitta, C.; Marcu, M.; Yarden, Y.; Neckers, L. Sensitivity of mature ErbB2 to geldanamycin is conferred by its kinase domain and is mediated by the chaperone protein hsp90. J. Biol. Chem. 2001, 276, 3702–3708.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 3702-3708
-
-
Xu, W.1
Mimnaugh, E.2
Rosser, M.F.3
Nicchitta, C.4
Marcu, M.5
Yarden, Y.6
Neckers, L.7
-
124
-
-
1942431966
-
The achilles heel of ErbB-2/Her2: Regulation by the hsp90 chaperone machine and potential for pharmacological intervention
-
Citri, A.; Kochupurakkal, B.S.; Yarden, Y. The achilles heel of ErbB-2/Her2: Regulation by the hsp90 chaperone machine and potential for pharmacological intervention. Cell Cycle 2004, 3, 51–60.
-
(2004)
Cell Cycle
, vol.3
, pp. 51-60
-
-
Citri, A.1
Kochupurakkal, B.S.2
Yarden, Y.3
-
125
-
-
38349132541
-
A critical role for hsp90 in cancer cell invasion involves interaction with the extracellular domain of Her-2
-
Sidera, K.; Gaitanou, M.; Stellas, D.; Matsas, R.; Patsavoudi, E. A critical role for hsp90 in cancer cell invasion involves interaction with the extracellular domain of Her-2. J. Biol. Chem. 2008, 283, 2031–2041.
-
(2008)
J. Biol. Chem
, vol.283
, pp. 2031-2041
-
-
Sidera, K.1
Gaitanou, M.2
Stellas, D.3
Matsas, R.4
Patsavoudi, E.5
-
126
-
-
0037291226
-
The crystal structure of a truncated ErbB2 ectodomain reveals an active conformation, poised to interact with other erbb receptors
-
Garrett, T.P.; McKern, N.M.; Lou, M.; Elleman, T.C.; Adams, T.E.; Lovrecz, G.O.; Kofler, M.; Jorissen, R.N.; Nice, E.C.; Burgess, A.W. et al. The crystal structure of a truncated ErbB2 ectodomain reveals an active conformation, poised to interact with other erbb receptors. Mol. Cell 2003, 11, 495–505.
-
(2003)
Mol. Cell
, vol.11
, pp. 495-505
-
-
Garrett, T.P.1
McKern, N.M.2
Lou, M.3
Elleman, T.C.4
Adams, T.E.5
Lovrecz, G.O.6
Kofler, M.7
Jorissen, R.N.8
Nice, E.C.9
Burgess, A.W.10
-
127
-
-
2442701289
-
The ErbB/Her receptor protein-tyrosine kinases and cancer
-
Roskoski, R., Jr. The ErbB/Her receptor protein-tyrosine kinases and cancer. Biochem. Biophys. Res. Commun. 2004, 319, 1–11.
-
(2004)
Biochem. Biophys. Res. Commun
, vol.319
, pp. 1-11
-
-
Roskoski, R.1
-
128
-
-
57149139395
-
Regulation of breast cancer metastasis by IGF signaling
-
Sachdev, D. Regulation of breast cancer metastasis by IGF signaling. J. Mammary Gland Biol. Neoplasia 2008, 13, 431–441.
-
(2008)
J. Mammary Gland Biol. Neoplasia
, vol.13
, pp. 431-441
-
-
Sachdev, D.1
-
129
-
-
56749110996
-
The type 1 insulin-like growth factor receptor pathway
-
Chitnis, M.M.; Yuen, J.S.; Protheroe, A.S.; Pollak, M.; Macaulay, V.M. The type 1 insulin-like growth factor receptor pathway. Clin. Cancer Res. 2008, 14, 6364–6370.
-
(2008)
Clin. Cancer Res
, vol.14
, pp. 6364-6370
-
-
Chitnis, M.M.1
Yuen, J.S.2
Protheroe, A.S.3
Pollak, M.4
Macaulay, V.M.5
-
130
-
-
0036559535
-
Elevated levels of IGF-1 receptor convey invasive and metastatic capability in a mouse model of pancreatic islet tumorigenesis
-
Lopez, T.; Hanahan, D. Elevated levels of IGF-1 receptor convey invasive and metastatic capability in a mouse model of pancreatic islet tumorigenesis. Cancer Cell 2002, 1, 339–353.
-
(2002)
Cancer Cell
, vol.1
, pp. 339-353
-
-
Lopez, T.1
Hanahan, D.2
-
131
-
-
74449085460
-
The type I insulin-like growth factor receptor regulates cancer metastasis independently of primary tumor growth by promoting invasion and survival
-
Sachdev, D.; Zhang, X.; Matise, I.; Gaillard-Kelly, M.; Yee, D. The type I insulin-like growth factor receptor regulates cancer metastasis independently of primary tumor growth by promoting invasion and survival. Oncogene 2010, 29, 251–262.
-
(2010)
Oncogene
, vol.29
, pp. 251-262
-
-
Sachdev, D.1
Zhang, X.2
Matise, I.3
Gaillard-Kelly, M.4
Yee, D.5
-
132
-
-
0035504405
-
Regulation of breast cancer cell motility by insulin receptor substrate-2 (IRS-2) in metastatic variants of human breast cancer cell lines
-
Jackson, J.G.; Zhang, X.; Yoneda, T.; Yee, D. Regulation of breast cancer cell motility by insulin receptor substrate-2 (IRS-2) in metastatic variants of human breast cancer cell lines. Oncogene 2001, 20, 7318–7325.
-
(2001)
Oncogene
, vol.20
, pp. 7318-7325
-
-
Jackson, J.G.1
Zhang, X.2
Yoneda, T.3
Yee, D.4
-
133
-
-
0027955344
-
Essential role of tyrosine residues 1131, 1135, and 1136 of the insulin-like growth factor-I (IGF-I) receptor in IGF-I action
-
Kato, H.; Faria, T.N.; Stannard, B.; Roberts, C.T., Jr.; LeRoith, D. Essential role of tyrosine residues 1131, 1135, and 1136 of the insulin-like growth factor-I (IGF-I) receptor in IGF-I action. Mol. Endocrinol. 1994, 8, 40-50.
-
(1994)
Mol. Endocrinol.
, vol.8
, pp. 40-50
-
-
Kato, H.1
Faria, T.N.2
Stannard, B.3
Roberts, C.T.4
Leroith, D.5
-
134
-
-
0034912833
-
A bone-seeking clone exhibits different biological properties from the MDA-MB-231 parental human breast cancer cells and a brain-seeking clone in vivo and in vitro
-
Yoneda, T.; Williams, P.J.; Hiraga, T.; Niewolna, M.; Nishimura, R. A bone-seeking clone exhibits different biological properties from the MDA-MB-231 parental human breast cancer cells and a brain-seeking clone in vivo and in vitro. J. Bone Miner. Res. 2001, 16, 1486-1495.
-
(2001)
J. Bone Miner. Res
, vol.16
, pp. 1486-1495
-
-
Yoneda, T.1
Williams, P.J.2
Hiraga, T.3
Niewolna, M.4
Nishimura, R.5
-
135
-
-
84865116604
-
Bone-derived IGF mediates crosstalk between bone and breast cancer cells in bony metastases
-
Hiraga, T.; Myoui, A.; Hashimoto, N.; Sasaki, A.; Hata, K.; Morita, Y.; Yoshikawa, H.; Rosen, C.J.; Mundy, G.R.; Yoneda, T. Bone-derived IGF mediates crosstalk between bone and breast cancer cells in bony metastases. Cancer Res. 2012, 72, 4238-4249.
-
(2012)
Cancer Res
, vol.72
, pp. 4238-4249
-
-
Hiraga, T.1
Myoui, A.2
Hashimoto, N.3
Sasaki, A.4
Hata, K.5
Morita, Y.6
Yoshikawa, H.7
Rosen, C.J.8
Mundy, G.R.9
Yoneda, T.10
-
136
-
-
84883549802
-
Inhibition of type I insulin-like growth factor receptor signaling attenuates the development of breast cancer brain metastasis
-
Saldana, S.M.; Lee, H.H.; Lowery, F.J.; Khotskaya, Y.B.; Xia, W.; Zhang, C; Chang, S.S.; Chou, C.K.; Steeg, P.S.; Yu, D. et al. Inhibition of type I insulin-like growth factor receptor signaling attenuates the development of breast cancer brain metastasis. PLOS ONE 2013, 8, e73406.
-
(2013)
PLOS ONE
, vol.8
-
-
Saldana, S.M.1
Lee, H.H.2
Lowery, F.J.3
Khotskaya, Y.B.4
Xia, W.5
Zhang, C.6
Chang, S.S.7
Chou, C.K.8
Steeg, P.S.9
Yu, D.10
-
137
-
-
84921912941
-
Expression patterns of stromal MMP-2 and tumoural MMP-2 and -9 are significant prognostic factors in invasive ductal carcinoma of the breast
-
Min, K.W.; Kim, D.H.; Do, S.I.; Kim, K.; Lee, H.J.; Chae, S.W.; Sohn, J.H.; Pyo, J.S.; Oh, Y.H.; Kim, W.S. et al. Expression patterns of stromal MMP-2 and tumoural MMP-2 and -9 are significant prognostic factors in invasive ductal carcinoma of the breast. Apmis 2014, 122, 1196-1206.
-
(2014)
Apmis
, vol.122
, pp. 1196-1206
-
-
Min, K.W.1
Kim, D.H.2
Do, S.I.3
Kim, K.4
Lee, H.J.5
Chae, S.W.6
Sohn, J.H.7
Pyo, J.S.8
Oh, Y.H.9
Kim, W.S.10
-
138
-
-
84866428075
-
Inhibiting matrix metalloproteinases, an old story with new potentials for cancer treatment
-
Stellas, D.; Patsavoudi, E. Inhibiting matrix metalloproteinases, an old story with new potentials for cancer treatment. Anticancer Agents Med. Chem. 2012, 12, 707–717.
-
(2012)
Anticancer Agents Med. Chem
, vol.12
, pp. 70
-
-
Stellas, D.1
Patsavoudi, E.2
-
139
-
-
0037155057
-
Matrix metalloproteinases in vascular remodeling and atherogenesis: The good, the bad, and the ugly
-
Galis, Z.S.; Khatri, J.J. Matrix metalloproteinases in vascular remodeling and atherogenesis: The good, the bad, and the ugly. Circ. Res. 2002, 90, 251-262.
-
(2002)
Circ. Res.
, vol.90
, pp. 251-262
-
-
Galis, Z.S.1
Khatri, J.J.2
-
140
-
-
84860389234
-
Activation of EGFR promotes squamous carcinoma SCC10A cell migration and invasion via inducing emt-like phenotype change and MMP-9-mediated degradation of E-cadherin
-
Zuo, J.H.; Zhu, W.; Li, MY.; Li, X.H.; Yi, H.; Zeng, G.Q.; Wan, X.X.; He, Q.Y.; Li, J.H.; Qu, J.Q. et al. Activation of EGFR promotes squamous carcinoma SCC10A cell migration and invasion via inducing emt-like phenotype change and MMP-9-mediated degradation of E-cadherin. J. Cell Biochem. 2011, 112, 2508-2517.
-
(2011)
J. Cell Biochem
, vol.112
, pp. 2508-2517
-
-
Zuo, J.H.1
Zhu, W.2
Li, M.Y.3
Li, X.H.4
Yi, H.5
Zeng, G.Q.6
Wan, X.X.7
He, Q.Y.8
Li, J.H.9
Qu, J.Q.10
-
141
-
-
11344280957
-
Extracellular roles for the molecular chaperone, hsp90
-
Eustace, B.K.; Jay, D.G. Extracellular roles for the molecular chaperone, hsp90. Cell Cycle 2004, 3, 1098-1100.
-
(2004)
Cell Cycle
, vol.3
, pp. 1098-1100
-
-
Eustace, B.K.1
Jay, D.G.2
-
142
-
-
77955372512
-
Monoclonal antibody 4C5 prevents activation of MMP2 and MMP9 by disrupting their interaction with extracellular HSP90 and inhibits formation of metastatic breast cancer cell deposits
-
Stellas, D.; El Hamidieh, A.; Patsavoudi, E. Monoclonal antibody 4C5 prevents activation of MMP2 and MMP9 by disrupting their interaction with extracellular HSP90 and inhibits formation of metastatic breast cancer cell deposits. BMC Cell Biol. 2010, doi: 10.1186/1471-2121-1111-1151.
-
(2010)
BMC Cell Biol
-
-
Stellas, D.1
El Hamidieh, A.2
Patsavoudi, E.3
-
143
-
-
3042703295
-
Three small integrin binding ligand n-linked glycoproteins (siblings) bind and activate specific matrix metalloproteinases
-
Fedarko, N.S.; Jain, A.; Karadag, A.; Fisher, L.W. Three small integrin binding ligand n-linked glycoproteins (siblings) bind and activate specific matrix metalloproteinases. FASEB. J. 2004, 18, 734-736.
-
(2004)
FASEB. J
, vol.18
, pp. 734-736
-
-
Fedarko, N.S.1
Jain, A.2
Karadag, A.3
Fisher, L.W.4
-
144
-
-
79959541003
-
The “ins” and “outs” of podosomes and invadopodia: Characteristics, formation and function
-
Murphy, D.A.; Courtneidge, S.A. The “ins” and “outs” of podosomes and invadopodia: Characteristics, formation and function. Nat. Rev. Mol. Cell Biol. 2011, 12, 413-426.
-
(2011)
Nat. Rev. Mol. Cell Biol
, vol.12
, pp. 413-426
-
-
Murphy, D.A.1
Courtneidge, S.A.2
-
145
-
-
84885449964
-
Rab40b regulates trafficking of MMP2 and MMP9 during invadopodia formation and invasion of breast cancer cells
-
Jacob, A.; Jing, J.; Lee, J.; Schedin, P.; Gilbert, S.M.; Peden, A.A.; Junutula, J.R.; Prekeris, R. Rab40b regulates trafficking of MMP2 and MMP9 during invadopodia formation and invasion of breast cancer cells. J. Cell Sci. 2013, 126, 4647-4658.
-
(2013)
J. Cell Sci
, vol.126
, pp. 4647-4658
-
-
Jacob, A.1
Jing, J.2
Lee, J.3
Schedin, P.4
Gilbert, S.M.5
Peden, A.A.6
Junutula, J.R.7
Prekeris, R.8
-
146
-
-
0035575616
-
Rab gtpases: Specifying and deciphering organelle identity and function
-
Pfeffer, S.R. Rab gtpases: Specifying and deciphering organelle identity and function. Trends Cell Biol. 2001, 11, 487-491.
-
(2001)
Trends Cell Biol
, vol.11
, pp. 487-491
-
-
Pfeffer, S.R.1
-
147
-
-
0036512208
-
New functions for the matrix metalloproteinases in cancer progression
-
Egeblad, M.; Werb, Z. New functions for the matrix metalloproteinases in cancer progression. Nat. Rev. Cancer 2002, 2, 161-174.
-
(2002)
Nat. Rev. Cancer
, vol.2
, pp. 161-174
-
-
Egeblad, M.1
Werb, Z.2
-
148
-
-
84896779371
-
The roles of mesenchymal stem cells in tumor inflammatory microenvironment
-
Sun, Z.; Wang, S.; Zhao, R.C. The roles of mesenchymal stem cells in tumor inflammatory microenvironment. J. Hematol. Oncol. 2014, doi: 10.1186/1756-8722-1187-1114.
-
(2014)
J. Hematol. Oncol
-
-
Sun, Z.1
Wang, S.2
Zhao, R.C.3
-
149
-
-
77955352820
-
Extracellular matrix proteins and tumor angiogenesis
-
Campbell, N.E.; Kellenberger, L.; Greenaway, J.; Moorehead, R.A.; Linnerth-Petrik, N.M.; Petrik, J. Extracellular matrix proteins and tumor angiogenesis. J. Oncol. 2010, doi:10.1155/2010/586905.
-
(2010)
J. Oncol
-
-
Campbell, N.E.1
Kellenberger, L.2
Greenaway, J.3
Moorehead, R.A.4
Linnerth-Petrik, N.M.5
Petrik, J.6
-
150
-
-
49549089512
-
VEGF release by MMP-9 mediated heparan sulphate cleavage induces colorectal cancer angiogenesis
-
Hawinkels, L.J.; Zuidwijk, K.; Verspaget, H.W.; de Jonge-Muller, E.S.; van Duijn, W.; Ferreira, V.; Fontijn, R.D.; David, G.; Hommes, D.W.; Lamers, C.B. et al. VEGF release by MMP-9 mediated heparan sulphate cleavage induces colorectal cancer angiogenesis. Eur. J. Cancer 2008, 44, 1904–1913.
-
(2008)
Eur. J. Cancer
, vol.44
, pp. 1904-1913
-
-
Hawinkels, L.J.1
Zuidwijk, K.2
Verspaget, H.W.3
De Jonge-Muller, E.S.4
Van Duijn, W.5
Ferreira, V.6
Fontijn, R.D.7
David, G.8
Hommes, D.W.9
Lamers, C.B.10
-
151
-
-
35148897176
-
Positive feedback regulation between MMP-9 and VEGF in human RPE cells
-
Hollborn, M.; Stathopoulos, C.; Steffen, A.; Wiedemann, P.; Kohen, L.; Bringmann, A. Positive feedback regulation between MMP-9 and VEGF in human RPE cells. Invest. Ophthalmol. Vis. Sci. 2007, 48, 4360–4367.
-
(2007)
Invest. Ophthalmol. Vis. Sci
, vol.48
, pp. 4360-4367
-
-
Hollborn, M.1
Stathopoulos, C.2
Steffen, A.3
Wiedemann, P.4
Kohen, L.5
Bringmann, A.6
-
152
-
-
22344437713
-
Processing of VEGF-A by matrix metalloproteinases regulates bioavailability and vascular patterning in tumors
-
Lee, S.; Jilani, S.M.; Nikolova, G.V.; Carpizo, D.; Iruela-Arispe, M.L. Processing of VEGF-A by matrix metalloproteinases regulates bioavailability and vascular patterning in tumors. J. Cell Biol. 2005, 169, 681–691.
-
(2005)
J. Cell Biol
, vol.169
, pp. 681-691
-
-
Lee, S.1
Jilani, S.M.2
Nikolova, G.V.3
Carpizo, D.4
Iruela-Arispe, M.L.5
-
153
-
-
0023868637
-
Molecular cloning and amino acid sequence of human enkephalinase (neutral endopeptidase)
-
Malfroy, B.; Kuang, W.J.; Seeburg, P.H.; Mason, A.J.; Schofield, P.R. Molecular cloning and amino acid sequence of human enkephalinase (neutral endopeptidase). FEBS Lett. 1988, 229, 206–210.
-
(1988)
FEBS Lett
, vol.229
, pp. 206-210
-
-
Malfroy, B.1
Kuang, W.J.2
Seeburg, P.H.3
Mason, A.J.4
Schofield, P.R.5
-
154
-
-
0030905306
-
The type 2 CD10/neutral endopeptidase 24.11 promoter: Functional characterization and tissue-specific regulation by CBF/NF-Y isoforms
-
Ishimaru, F.; Mari, B.; Shipp, M.A. The type 2 CD10/neutral endopeptidase 24.11 promoter: Functional characterization and tissue-specific regulation by CBF/NF-Y isoforms. Blood 1997, 89, 4136–4145.
-
(1997)
Blood
, vol.89
, pp. 4136-4145
-
-
Ishimaru, F.1
Mari, B.2
Shipp, M.A.3
-
155
-
-
0033653064
-
Neutral endopeptidase inhibits prostate cancer cell migration by blocking focal adhesion kinase signaling
-
Sumitomo, M.; Shen, R.; Walburg, M.; Dai, J.; Geng, Y.; Navarro, D.; Boileau, G.; Papandreou, C.N.; Giancotti, F.G.; Knudsen, B. et al. Neutral endopeptidase inhibits prostate cancer cell migration by blocking focal adhesion kinase signaling. J. Clin. Invest. 2000, 106, 1399–1407.
-
(2000)
J. Clin. Invest.
, vol.106
, pp. 1399-1407
-
-
Sumitomo, M.1
Shen, R.2
Walburg, M.3
Dai, J.4
Geng, Y.5
Navarro, D.6
Boileau, G.7
Papandreou, C.N.8
Giancotti, F.G.9
Knudsen, B.10
-
156
-
-
0025986666
-
CD10 (CALLA)/neutral endopeptidase 24.11 modulates inflammatory peptide-induced changes in neutrophil morphology, migration, and adhesion proteins and is itself regulated by neutrophil activation
-
Shipp, M.A.; Stefano, G.B.; Switzer, S.N.; Griffin, J.D.; Reinherz, E.L. CD10 (CALLA)/neutral endopeptidase 24.11 modulates inflammatory peptide-induced changes in neutrophil morphology, migration, and adhesion proteins and is itself regulated by neutrophil activation. Blood 1991, 78, 1834–1841.
-
(1991)
Blood
, vol.78
, pp. 1834-1841
-
-
Shipp, M.A.1
Stefano, G.B.2
Switzer, S.N.3
Griffin, J.D.4
Reinherz, E.L.5
-
157
-
-
77956641571
-
The CD10 enzyme is a key player to identify and regulate human mammary stem cells
-
Bachelard-Cascales, E.; Chapellier, M.; Delay, E.; Pochon, G.; Voeltzel, T.; Puisieux, A.; Caron de Fromentel, C.; Maguer-Satta, V. The CD10 enzyme is a key player to identify and regulate human mammary stem cells. Stem Cells 2010, 28, 1081–1088.
-
(2010)
Stem Cells
, vol.28
, pp. 1081-1088
-
-
Bachelard-Cascales, E.1
Chapellier, M.2
Delay, E.3
Pochon, G.4
Voeltzel, T.5
Puisieux, A.6
De Caron Fromentel, C.7
Maguer-Satta, V.8
-
158
-
-
19444377832
-
Epithelial progenitors in the normal human mammary gland
-
Stingl, J.; Raouf, A.; Emerman, J.T.; Eaves, C.J. Epithelial progenitors in the normal human mammary gland. J. Mammary Gland Biol. Neoplasia 2005, 10, 49–59.
-
(2005)
J. Mammary Gland Biol. Neoplasia
, vol.10
, pp. 49-59
-
-
Stingl, J.1
Raouf, A.2
Emerman, J.T.3
Eaves, C.J.4
-
159
-
-
0027102389
-
CD10/neutral endopeptidase 24.11 in developing human fetal lung. Patterns of expression and modulation of peptide-mediatedproliferation
-
Sunday, M.E.; Hua, J.; Torday, J.S.; Reyes, B.; Shipp, M.A. CD10/neutral endopeptidase 24.11 in developing human fetal lung. Patterns of expression and modulation of peptide-mediated proliferation. J. Clin. Invest. 1992, 90, 2517–2525.
-
(1992)
J. Clin. Invest
, vol.90
, pp. 2517-2525
-
-
Sunday, M.E.1
Hua, J.2
Torday, J.S.3
Reyes, B.4
Shipp, M.A.5
-
160
-
-
34548386234
-
Novel markers for the prospective isolation of human msc
-
Buhring, H.J.; Battula, V.L.; Treml, S.; Schewe, B.; Kanz, L.; Vogel, W. Novel markers for the prospective isolation of human msc. Ann. N. Y. Acad. Sci. 2007, 1106, 262–271.
-
(2007)
Ann. N. Y. Acad. Sci
, vol.1106
, pp. 262-271
-
-
Buhring, H.J.1
Battula, V.L.2
Treml, S.3
Schewe, B.4
Kanz, L.5
Vogel, W.6
-
161
-
-
23944462375
-
Anti-progressive effect of neutral endopeptidase 24.11 (NEP/CD10) on cervical carcinoma in vitro and in vivo
-
Terauchi, M.; Kajiyama, H.; Shibata, K.; Ino, K.; Mizutani, S.; Kikkawa, F. Anti-progressive effect of neutral endopeptidase 24.11 (NEP/CD10) on cervical carcinoma in vitro and in vivo. Oncology 2005, 69, 52–62.
-
(2005)
Oncology
, vol.69
, pp. 52-62
-
-
Terauchi, M.1
Kajiyama, H.2
Shibata, K.3
Ino, K.4
Mizutani, S.5
Kikkawa, F.6
-
162
-
-
0035434869
-
Neutral endopeptidase/CD10 and aminopeptidase N/CD13 gene expression as a prognostic factor in non-small cell lung Cancer
-
Tokuhara, T.; Adachi, M.; Hashida, H.; Ishida, H.; Taki, T.; Higashiyama, M.; Kodama, K.; Tachibana, S.; Sasaki, S.; Miyake, M. Neutral endopeptidase/CD10 and aminopeptidase N/CD13 gene expression as a prognostic factor in non-small cell lung Cancer. Jpn. J. Thorac. Cardiovasc. Surg. 2001, 49, 489–496.
-
(2001)
Jpn. J. Thorac. Cardiovasc. Surg
, vol.49
, pp. 489-496
-
-
Tokuhara, T.1
Adachi, M.2
Hashida, H.3
Ishida, H.4
Taki, T.5
Higashiyama, M.6
Kodama, K.7
Tachibana, S.8
Sasaki, S.9
Miyake, M.10
-
163
-
-
77956133518
-
CD10+ pancreatic stellate cells enhance the progression of pancreatic cancer
-
Ikenaga, N.; Ohuchida, K.; Mizumoto, K.; Cui, L.; Kayashima, T.; Morimatsu, K.; Moriyama, T.; Nakata, K.; Fujita, H.; Tanaka, M. CD10+ pancreatic stellate cells enhance the progression of pancreatic cancer. Gastroenterology 2010, 139, 1041–1051.
-
(2010)
Gastroenterology
, vol.139
, pp. 1041-1051
-
-
Ikenaga, N.1
Ohuchida, K.2
Mizumoto, K.3
Cui, L.4
Kayashima, T.5
Morimatsu, K.6
Moriyama, T.7
Nakata, K.8
Fujita, H.9
Tanaka, M.10
-
164
-
-
79953012136
-
Concise review: Neutral endopeptidase (CD10): A multifaceted environment actor in stem cells, physiological mechanisms, and cancer
-
Maguer-Satta, V.; Besancon, R.; Bachelard-Cascales, E. Concise review: Neutral endopeptidase (CD10): A multifaceted environment actor in stem cells, physiological mechanisms, and cancer. Stem Cells 2011, 29, 389–396.
-
(2011)
Stem Cells
, vol.29
, pp. 389-396
-
-
Maguer-Satta, V.1
Besancon, R.2
Bachelard-Cascales, E.3
-
165
-
-
84872164542
-
CD10 and E-cad expression in urinary bladder urothelial and squamous cell carcinoma
-
Omran, O.M. CD10 and E-cad expression in urinary bladder urothelial and squamous cell carcinoma. J. Environ. Pathol. Toxicol. Oncol. 2012, 31, 203–212.
-
(2012)
J. Environ. Pathol. Toxicol. Oncol
, vol.31
, pp. 203-212
-
-
Omran, O.M.1
-
166
-
-
77951718259
-
Stromal CD10 expression and relationship to the E-cadherin/beta-catenin complex in breast carcinoma
-
Kim, H.S.; Kim, G.Y.; Kim, Y.W.; Park, Y.K.; Song, J.Y.; Lim, S.J. Stromal CD10 expression and relationship to the E-cadherin/beta-catenin complex in breast carcinoma. Histopathology 2010, 56, 708–719.
-
(2010)
Histopathology
, vol.56
, pp. 708-719
-
-
Kim, H.S.1
Kim, G.Y.2
Kim, Y.W.3
Park, Y.K.4
Song, J.Y.5
Lim, S.J.6
-
167
-
-
33845699283
-
Stromal CD10
-
Makretsov, N.A.; Hayes, M.; Carter, B.A.; Dabiri, S.; Gilks, C.B.; Huntsman, D.G. Stromal CD10 expression in invasive breast carcinoma correlates with poor prognosis, estrogen receptor negativity, and high grade. Mod. Pathol. 2007, 20, 84–89.
-
(2007)
Mod. Pathol
, vol.20
, pp. 84-89
-
-
Makretsov, N.A.1
Hayes, M.2
Carter, B.A.3
Dabiri, S.4
Gilks, C.B.5
Huntsman, D.G.6
-
168
-
-
84856681391
-
Twist1 is an independent prognostic factor of esophageal squamous cell carcinoma and associated with itsepithelial-mesenchymal transition
-
Lee, K.W.; Kim, J.H.; Han, S.; Sung, C.O.; Do, I.G.; Ko, Y.H.; Um, S.H.; Kim, S.H. Twist1 is an independent prognostic factor of esophageal squamous cell carcinoma and associated with its epithelial-mesenchymal transition. Ann. Surg. Oncol. 2012, 19, 326–335.
-
(2012)
Ann. Surg. Oncol
, vol.19
, pp. 326-335
-
-
Lee, K.W.1
Kim, J.H.2
Han, S.3
Sung, C.O.4
Do, I.G.5
Ko, Y.H.6
Um, S.H.7
Kim, S.H.8
-
169
-
-
84921907685
-
CD10 expression is enhanced by twist1 and associated with poor prognosis in esophageal squamous cell carcinoma with facilitating tumorigenicity in vitro and in vivo
-
Lee, K.W.; Sung, C.O.; Kim, J.H.; Kang, M.; Yoo, H.Y.; Kim, H.H.; Um, S.H.; Kim, S.H. CD10 expression is enhanced by twist1 and associated with poor prognosis in esophageal squamous cell carcinoma with facilitating tumorigenicity in vitro and in vivo. Int. J. Cancer 2015, 136, 310–321.
-
(2015)
Int. J. Cancer
, vol.136
, pp. 310-321
-
-
Lee, K.W.1
Sung, C.O.2
Kim, J.H.3
Kang, M.4
Yoo, H.Y.5
Kim, H.H.6
Um, S.H.7
Kim, S.H.8
-
170
-
-
8544274533
-
Involvement of cell surface hsp90 in cell migration reveals a novel role in the developing nervous system
-
Sidera, K.; Samiotaki, M.; Yfanti, E.; Panayotou, G.; Patsavoudi, E. Involvement of cell surface hsp90 in cell migration reveals a novel role in the developing nervous system. J. Biol. Chem. 2004, 279, 45379–45388.
-
(2004)
J. Biol. Chem
, vol.279
, pp. 45379-45388
-
-
Sidera, K.1
Samiotaki, M.2
Yfanti, E.3
Panayotou, G.4
Patsavoudi, E.5
-
171
-
-
0842329639
-
Induction of
-
Becker, B.; Multhoff, G.; Farkas, B.; Wild, P.J.; Landthaler, M.; Stolz, W.; Vogt, T. Induction of hsp90 protein expression in malignant melanomas and melanoma metastases. Exp. Dermatol. 2004, 13, 27–32.
-
(2004)
Exp. Dermatol
, vol.13
, pp. 27-32
-
-
Becker, B.1
Multhoff, G.2
Farkas, B.3
Wild, P.J.4
Landthaler, M.5
Stolz, W.6
Vogt, T.7
-
172
-
-
34250172746
-
Monoclonal antibody 4C5 immunostains human melanomas and inhibits melanoma cell invasion and metastasis
-
Stellas, D.; Karameris, A.; Patsavoudi, E. Monoclonal antibody 4C5 immunostains human melanomas and inhibits melanoma cell invasion and metastasis. Clin. Cancer Res. 2007, 13, 1831–1838.
-
(2007)
Clin. Cancer Res
, vol.13
, pp. 1831-1838
-
-
Stellas, D.1
Karameris, A.2
Patsavoudi, E.3
-
173
-
-
69849107530
-
Impact of heat-shock protein 90 on cancer metastasis
-
Tsutsumi, S.; Beebe, K.; Neckers, L. Impact of heat-shock protein 90 on cancer metastasis. Future Oncol. 2009, 5, 679–688.
-
(2009)
Futureoncol
, vol.5
, pp. 679-688
-
-
Tsutsumi, S.1
Beebe, K.2
Neckers, L.3
-
174
-
-
49649108912
-
Role of acetylation and extracellular location of heat shock protein 90alpha in tumor cell invasion
-
Yang, Y.; Rao, R.; Shen, J.; Tang, Y.; Fiskus, W.; Nechtman, J.; Atadja, P.; Bhalla, K. Role of acetylation and extracellular location of heat shock protein 90alpha in tumor cell invasion. Cancer Res. 2008, 68, 4833–4842.
-
(2008)
Cancer Res
, vol.68
, pp. 4833-4842
-
-
Yang, Y.1
Rao, R.2
Shen, J.3
Tang, Y.4
Fiskus, W.5
Nechtman, J.6
Atadja, P.7
Bhalla, K.8
-
175
-
-
84857038878
-
Secreted heat shock protein-90 (hsp90) in wound healing and Cancer
-
Li, W.; Sahu, D.; Tsen, F. Secreted heat shock protein-90 (hsp90) in wound healing and Cancer. Biochim. Biophys. Acta 2012, 1823, 730–741.
-
(2012)
Biochim. Biophys. Acta
, vol.1823
, pp. 730-741
-
-
Li, W.1
Sahu, D.2
Tsen, F.3
-
176
-
-
84921913131
-
-
Greece, Personal observations
-
Stivarou, T.; Vartzi, G.; Thomaidou, D.; Patsavoudi, E. Hellenic Pasteur Institute, Athens, Greece, 2015, Personal observations.
-
(2015)
Hellenic Pasteur Institute, Athens
-
-
Stivarou, T.1
Vartzi, G.2
Thomaidou, D.3
Patsavoudi, E.4
-
177
-
-
12344291243
-
Hsp90 and cdc37—A chaperone cancer conspiracy
-
Pearl, L.H. Hsp90 and cdc37—A chaperone cancer conspiracy. Curr. Opin. Genet. Dev. 2005, 15, 55–61.
-
(2005)
Curr. Opin. Genet. Dev
, vol.15
, pp. 55-61
-
-
Pearl, L.H.1
-
178
-
-
59449107850
-
Targeting cdc37: An alternative, kinase-directed strategy for disruption of oncogenic chaperoning
-
Smith, J.R.; Workman, P. Targeting cdc37: An alternative, kinase-directed strategy for disruption of oncogenic chaperoning. Cell Cycle 2009, 8, 362–372.
-
(2009)
Cell Cycle
, vol.8
, pp. 362-372
-
-
Smith, J.R.1
Workman, P.2
-
179
-
-
0032493624
-
P50(cdc37) binds directly to the catalytic domain of raf as well as to a site on hsp90 that is topologically adjacent to the tetratricopeptide repeat binding site
-
Silverstein, A.M.; Grammatikakis, N.; Cochran, B.H.; Chinkers, M.; Pratt, W.B. P50(cdc37) binds directly to the catalytic domain of raf as well as to a site on hsp90 that is topologically adjacent to the tetratricopeptide repeat binding site. J. Biol. Chem. 1998, 273, 20090–20095.
-
(1998)
J. Biol. Chem
, vol.273
, pp. 20090-20095
-
-
Silverstein, A.M.1
Grammatikakis, N.2
Cochran, B.H.3
Chinkers, M.4
Pratt, W.B.5
-
180
-
-
0030745769
-
Cdc37 is a molecular chaperone with specific functions in signal transduction
-
Kimura, Y.; Rutherford, S.L.; Miyata, Y.; Yahara, I.; Freeman, B.C.; Yue, L.; Morimoto, R.I.; Lindquist, S. Cdc37 is a molecular chaperone with specific functions in signal transduction. Genes Dev. 1997, 11, 1775–1785.
-
(1997)
Genes Dev
, vol.11
, pp. 1775-1785
-
-
Kimura, Y.1
Rutherford, S.L.2
Miyata, Y.3
Yahara, I.4
Freeman, B.C.5
Yue, L.6
Morimoto, R.I.7
Lindquist, S.8
-
181
-
-
0034720777
-
P50(cdc37) is a nonexclusive hsp90 cohort which participates intimately in hsp90-mediated folding of immature kinase molecules
-
Hartson, S.D.; Irwin, A.D.; Shao, J.; Scroggins, B.T.; Volk, L.; Huang, W.; Matts, R.L. P50(cdc37) is a nonexclusive hsp90 cohort which participates intimately in hsp90-mediated folding of immature kinase molecules. Biochemistry 2000, 39, 7631–7644.
-
(2000)
Biochemistry
, vol.39
, pp. 7631-7644
-
-
Hartson, S.D.1
Irwin, A.D.2
Shao, J.3
Scroggins, B.T.4
Volk, L.5
Huang, W.6
Matts, R.L.7
-
182
-
-
84865104330
-
Cell surface cdc37 participates in extracellular hsp90 mediated cancer cell invasion
-
El Hamidieh, A.; Grammatikakis, N.; Patsavoudi, E. Cell surface cdc37 participates in extracellular hsp90 mediated cancer cell invasion. PLOS ONE 2012, 7, e42722.
-
(2012)
PLOS ONE
, vol.7
-
-
El Hamidieh, A.1
Grammatikakis, N.2
Patsavoudi, E.3
-
183
-
-
67651007506
-
The serine protease inhibitor protease nexin-1 controls mammary cancer metastasis through LRP-1-mediated MMP-9 expression
-
Fayard, B.; Bianchi, F.; Dey, J.; Moreno, E.; Djaffer, S.; Hynes, N.E.; Monard, D. The serine protease inhibitor protease nexin-1 controls mammary cancer metastasis through LRP-1-mediated MMP-9 expression. Cancer Res. 2009, 69, 5690–5698.
-
(2009)
Cancer Res
, vol.69
, pp. 5690-5698
-
-
Fayard, B.1
Bianchi, F.2
Dey, J.3
Moreno, E.4
Djaffer, S.5
Hynes, N.E.6
Monard, D.7
-
184
-
-
59149098234
-
Low-density lipoprotein receptor-related protein 1 promotes cancer cell migration and invasion by inducing the expression of matrix metalloproteinases 2 and 9
-
Song, H.; Li, Y.; Lee, J.; Schwartz, A.L.; Bu, G. Low-density lipoprotein receptor-related protein 1 promotes cancer cell migration and invasion by inducing the expression of matrix metalloproteinases 2 and 9. Cancer Res. 2009, 69, 879–886.
-
(2009)
Cancer Res
, vol.69
, pp. 879-886
-
-
Song, H.1
Li, Y.2
Lee, J.3
Schwartz, A.L.4
Bu, G.5
-
185
-
-
84880054952
-
Myeloid cell receptor LRP1/CD91 regulates monocyte recruitment and angiogenesis in tumors
-
Staudt, N.D.; Jo, M.; Hu, J.; Bristow, J.M.; Pizzo, D.P.; Gaultier, A.; VandenBerg, S.R.; Gonias, S.L. Myeloid cell receptor LRP1/CD91 regulates monocyte recruitment and angiogenesis in tumors. Cancer Res. 2013, 73, 3902–3912.
-
(2013)
Cancer Res
, vol.73
, pp. 3902-3912
-
-
Staudt, N.D.1
Jo, M.2
Hu, J.3
Bristow, J.M.4
Pizzo, D.P.5
Gaultier, A.6
Vandenberg, S.R.7
Gonias, S.L.8
-
186
-
-
84893100525
-
Extracellular heat shock protein 90 signals through subdomain II and the npvy motif of LRP-1 receptor to AKT1 and AKT2: A circuit essential for promoting skin cell migration in vitro and wound healing in vivo
-
Tsen, F.; Bhatia, A.; O’Brien, K.; Cheng, C.F.; Chen, M.; Hay, N.; Stiles, B.; Woodley, D.T.; Li, W. Extracellular heat shock protein 90 signals through subdomain II and the npvy motif of LRP-1 receptor to AKT1 and AKT2: A circuit essential for promoting skin cell migration in vitro and wound healing in vivo. Mol. Cell Biol. 2013, 33, 4947–4959.
-
(2013)
Mol. Cell Biol
, vol.33
, pp. 4947-4959
-
-
Tsen, F.1
Bhatia, A.2
O’Brien, K.3
Cheng, C.F.4
Chen, M.5
Hay, N.6
Stiles, B.7
Woodley, D.T.8
Li, W.9
-
187
-
-
35448935962
-
The low-density lipoprotein receptor-related protein regulates cancer cell survival and metastasis development
-
Montel, V.; Gaultier, A.; Lester, R.D.; Campana, W.M.; Gonias, S.L. The low-density lipoprotein receptor-related protein regulates cancer cell survival and metastasis development. Cancer Res. 2007, 67, 9817–9824.
-
(2007)
Cancer Res
, vol.67
, pp. 9817-9824
-
-
Montel, V.1
Gaultier, A.2
Lester, R.D.3
Campana, W.M.4
Gonias, S.L.5
-
188
-
-
79952433556
-
A novel extracellular hsp90 mediated co-receptor function for LRP1 regulates EphA2 dependent glioblastoma cell invasion
-
Gopal, U.; Bohonowych, J.E.; Lema-Tome, C.; Liu, A.; Garrett-Mayer, E.; Wang, B.; Isaacs, J.S. A novel extracellular hsp90 mediated co-receptor function for LRP1 regulates EphA2 dependent glioblastoma cell invasion. PLOS ONE 2011, 6, e17649.
-
(2011)
PLOS ONE
, vol.6
-
-
Gopal, U.1
Bohonowych, J.E.2
Lema-Tome, C.3
Liu, A.4
Garrett-Mayer, E.5
Wang, B.6
Isaacs, J.S.7
-
189
-
-
57749121465
-
The EphA2 receptor and ephrina1 ligand in solid tumors: Function and therapeutic targeting
-
Wykosky, J.; Debinski, W. The EphA2 receptor and ephrina1 ligand in solid tumors: Function and therapeutic targeting. Mol. Cancer Res. 2008, 6, 1795–1806.
-
(2008)
Mol. Cancer Res
, vol.6
, pp. 1795-1806
-
-
Wykosky, J.1
Debinski, W.2
-
190
-
-
42349102043
-
LRP-1 silencing prevents malignant cell invasion despite increased pericellular proteolytic activities
-
Dedieu, S.; Langlois, B.; Devy, J.; Sid, B.; Henriet, P.; Sartelet, H.; Bellon, G.; Emonard, H.; Martiny, L. LRP-1 silencing prevents malignant cell invasion despite increased pericellular proteolytic activities. Mol. Cell Biol. 2008, 28, 2980–2995.
-
(2008)
Mol. Cell Biol
, vol.28
, pp. 2980-2995
-
-
Dedieu, S.1
Langlois, B.2
Devy, J.3
Sid, B.4
Henriet, P.5
Sartelet, H.6
Bellon, G.7
Emonard, H.8
Martiny, L.9
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