메뉴 건너뛰기




Volumn 106, Issue 11, 2000, Pages 1399-1407

Neutral endopeptidase inhibits prostate cancer cell migration by blocking focal adhesion kinase signaling

Author keywords

[No Author keywords available]

Indexed keywords

ANDROGEN; BOMBESIN; CELL ENZYME; ENDOTHELIN 1; FOCAL ADHESION KINASE; MEMBRANE METALLOENDOPEPTIDASE; NEUROPEPTIDE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN P85; RECOMBINANT ENZYME; TETRACYCLINE; TYROSINE;

EID: 0033653064     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI10536     Document Type: Article
Times cited : (126)

References (41)
  • 4
    • 0025885695 scopus 로고
    • CD10/neutral endopeptidase 24.11 hydrolyzes bombesin-like peptides and regulates the growth of small cell carcinomas of the lung
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 10662-10666
    • Shipp, M.A.1
  • 5
    • 0027244148 scopus 로고
    • Hematopoietic differentiation antigens that are membrane-associated enzymes: Cutting is the key!
    • (1993) Blood , vol.82 , pp. 1052-1070
    • Shipp, M.A.1    Look, A.T.2
  • 6
    • 0031889217 scopus 로고    scopus 로고
    • Neutral endopeptidase 24.11 loss in metastatic human prostate cancer contributes to androgen-independent progression
    • (1998) Nat. Med. , vol.4 , pp. 50-57
    • Papandreou, C.N.1
  • 8
    • 0031908778 scopus 로고    scopus 로고
    • CD10 inhibitors increase f-Met-Leu-Phe-induced neutrophil transmigration
    • (1998) J. Leukoc. Biol. , vol.63 , pp. 312-320
    • Hofman, P.1
  • 10
  • 11
    • 0033229711 scopus 로고    scopus 로고
    • Expression of CD10 by human T cells that undergo apoptosis both in vitro and in vivo
    • (1999) Blood , vol.94 , pp. 3067-3076
    • Cutrona, G.1
  • 12
    • 0028269336 scopus 로고
    • N-Phosphonomethyl dipeptides and their phosphonate prodrugs, a new generation of neutral endopeptidase (NEP, EC 3.4.24.11) inhibitors
    • (1994) J. Med. Chem. , vol.37 , pp. 498-511
    • De Lombaert, S.1
  • 14
    • 0023855428 scopus 로고
    • Expression of neutral endopeptidase (enkephalinase) in hererologous COS-1 cells. Characterization of the recombinant enzyme and evidence for a glutamic acid residue at the active site
    • (1988) J. Biol. Chem. , vol.263 , pp. 4033-4040
    • Devault, A.1
  • 15
    • 0034456723 scopus 로고    scopus 로고
    • Androgen-induced growth inhibition of androgen receptor expressing androgen-independent prostate cancer cells is mediated by increased levels of neutral endopeptidase
    • (2000) Endocrinology , vol.141 , pp. 1699-1704
    • Shen, R.1
  • 18
    • 0026476697 scopus 로고
    • Focal adhesion kinase (p125FAK): A point of convergence in the action of neuropeptides, integrins, and oncogenes
    • (1992) Cell , vol.71 , pp. 891-894
    • Zachary, I.1    Rozengurt, E.2
  • 19
    • 0033214460 scopus 로고    scopus 로고
    • Bombesin and platelet-derived growth Factor induce association of endogenous focal adhesion kinase with Src in intact Swiss 3T3 cells
    • (1999) J. Biol. Chem. , vol.274 , pp. 28371-28378
    • Salazar, E.P.1    Rozengurt, E.2
  • 20
    • 0029795243 scopus 로고    scopus 로고
    • Focal adhesion kinase (pp125FAK) expression, activation and association with paxillin and p50CSK in human metastatic prostate carcinoma
    • (1996) Int. J. Cancer , vol.68 , pp. 164-171
    • Tremblay, L.1
  • 24
    • 0028350859 scopus 로고
    • Autophosphorylation of the focal adhesion kinase, pp125FAK, directs SH2-dependent binding of pp60src
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 1680-1688
    • Schaller, M.D.1
  • 25
    • 0031741856 scopus 로고    scopus 로고
    • Signal transduction pathways in the mitogenic response to G protein-coupled neuropeptide receptor agonists
    • (1998) J. Cell. Physiol. , vol.177 , pp. 507-517
    • Rozengurt, E.1
  • 26
    • 0033617357 scopus 로고    scopus 로고
    • Requirement of phosphatidylinositoi 3-kinase in focal adhesion kinase-promoted cell migration
    • (1999) J. Biol. Chem. , vol.274 , pp. 12361-12366
    • Reiske, H.R.1
  • 27
    • 0034075990 scopus 로고    scopus 로고
    • Methylation of the neutral endopeptidase gene promoter in human prostate cancers
    • (2000) Clin. Cancer Res. , vol.6 , pp. 1664-1670
    • Usmani, B.A.1
  • 29
    • 0031921101 scopus 로고    scopus 로고
    • Multiple Grb2-mediated integtin-stimulated signaling pathways to ERK2/mitogen-activated protein kinase: Summation of both c-Src-and focal adhesion kinaseinitiated tyrosine phosphorylation events
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 2571-2585
    • Schlaepfer, D.D.1    Jones, K.C.2    Hunter, T.3
  • 31
    • 0033566290 scopus 로고    scopus 로고
    • High frequency of adhesion defects in Blineage acute lymphoblastic leukemia
    • (1999) Blood , vol.94 , pp. 754-764
    • Geijtenbeek, T.B.1
  • 32
    • 0028951464 scopus 로고
    • Integrin-dependent translocation of phosphoinositide 3-kinase to the cytoskeleton of thrombin-activated platelets involves specific interactions of p85 alpha with actin filaments and focal adhesion kinase
    • (1995) J. Cell. Biol. , vol.129 , pp. 831-842
    • Guinebault, C.1
  • 36
    • 0032511031 scopus 로고    scopus 로고
    • Phosphoinositide 3-OH kinase activates the beta2 integrin adhesion pathway and induces membrane recruitment of cytohesin-1
    • (1998) J. Biol. Chem. , vol.273 , pp. 14853-14861
    • Nagel, W.1
  • 37
    • 0032586952 scopus 로고    scopus 로고
    • Stimulation of beta1-integrin function by epidermal growth factor and heregulin-beta has distinct requirements for erbB2 but a similar dependence on phosphoinositide 3-OH kinase
    • (1999) Mol. Biol. Cell , vol.10 , pp. 2861-2878
    • Adelsman, M.A.1    McCarthy, J.B.2    Shimizu, Y.3
  • 40
    • 0033599039 scopus 로고    scopus 로고
    • EGF receptor transactivation by G-protein-coupled receptors requires metalloproteinase cleavage of proHB-EGF
    • (1999) Nature , vol.402 , pp. 884-888
    • Prenzel, N.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.