Rab40b regulates trafficking of MMP2 and MMP9 during invadopodia formation and invasion of breast cancer cells

Journal of Cell Science

Volumn 126, Issue 20, 2013, Pages 4647-4658

  Jacob, Abitha ^a   Jing, Jian ^a   Lee, James ^b   Schedin, Pepper ^a   Gilbert, Simon M ^c   Peden, Andrew A ^d   Junutula, Jagath R ^b   Prekeris, Rytis ^a  

^a UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^b GENENTECH INC   (United States)

^c UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^d UNIVERSITY OF SHEFFIELD   (United Kingdom)

Author keywords

Invadopodia; Invasion; MMP2; MMP9; Rab40b; Secretion

Indexed keywords

CELL MEMBRANE PROTEIN; GELATINASE A; GELATINASE B; GUANOSINE TRIPHOSPHATASE; MEMBRANE PROTEIN; RAB PROTEIN; RAB40B PROTEIN; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; VAMP4 PROTEIN;

ARTICLE; BASEMENT MEMBRANE; BREAST CANCER; BREAST METASTASIS; CANCER CELL; CELL INVASION; CONTROLLED STUDY; DEGRADATION KINETICS; HUMAN; HUMAN CELL; INVADOPODIA; MEMBRANE STRUCTURE; MEMBRANE TRANSPORT; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN SECRETION; PROTEIN TARGETING; PROTEIN TRANSPORT; REGULATORY MECHANISM; SECRETORY VESICLE; TUMOR GROWTH;

INVADOPODIA; INVASION; MMP2; MMP9; RAB40B; SECRETION;

BREAST NEOPLASMS; CELL LINE, TUMOR; FEMALE; HUMANS; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; NEOPLASM INVASIVENESS; PSEUDOPODIA; RAB GTP-BINDING PROTEINS; RNA, SMALL INTERFERING; TRANSFECTION;

EID: 84885449964     PISSN: 00219533     EISSN: 14779137     Source Type: Journal    
DOI: 10.1242/jcs.126573     Document Type: Article

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