Rapid expression and activation of MMP-2 and MMP-9 upon exposure of human breast cancer cells (MCF-7) to fibronectin in serum free medium

Life Sciences

Volumn 82, Issue 9-10, 2008, Pages 467-476

  Das, Shamik ^a   Banerji, Aniruddha ^a   Frei, Eva ^b   Chatterjee, Amitava ^a  

^a CHITTARANJAN NATIONAL CANCER INSTITUTE   (India)

^b GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

Author keywords

ERK; Fibronectin; MMP 2; MMP 9; MT1 MMP; NF B; PI 3K

Indexed keywords

FIBRONECTIN; GELATINASE A; GELATINASE B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MONOCLONAL ANTIBODY; PHOSPHATIDYLINOSITOL 3 KINASE; VERY LATE ACTIVATION ANTIGEN 5;

AMINO ACID SEQUENCE; ARTICLE; BREAST CANCER; CELL ADHESION; CELL STRAIN MCF 7; CONTROLLED STUDY; EXTRACELLULAR MATRIX; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOCYTOCHEMISTRY; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; ZYMOGRAPHY;

1-PHOSPHATIDYLINOSITOL 3-KINASE; BREAST NEOPLASMS; CELL ADHESION; CELL LINE, TUMOR; CELL MOVEMENT; CHROMONES; CULTURE MEDIA, SERUM-FREE; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; ENZYME INHIBITORS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FIBRONECTINS; FLAVONOIDS; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; MATRIX METALLOPROTEINASE 14; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; MORPHOLINES; NF-KAPPA B; PEPTIDE FRAGMENTS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TIME FACTORS;

EID: 39149084984     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lfs.2007.12.013     Document Type: Article

References (45)

1. Akiyama S.K., Olden K., and Yamada K.M. Fibronectin and integrins in invasion and metastasis. Cancer and Metastasis Reviews 14 3 (1995) 173-189
2. Andela V.B., Schwarz E.M., Puzas J.E., O'Keefe R.J., and Rosier R.N. Tumour metastasis and the reciprocal regulation of prometastatic and antimetastatic factors by nuclear factor kappa B. Cancer Research 60 23 (2000) 6557-6562
3. Bodary S.C., and Mclean J.W. The integrin beta 1 subunit associates with the vitronectin receptor alpha v subunit to form a novel vitronectin receptor in a human embryonic kidney cell line. The Journal of Biological Chemistry 265 11 (1990) 5938-5941
4. Brown P.D., Kleiner D.E., Unsworth E.J., and Stetler-Stevenson W.G. Cellular activation of the 72 kDa type IV procollagenase/TIMP-2 complex. Kidney International 43 1 (1993) 163-170
5. Chase A.J., Bond M., Crook M.F., and Newby A.C. Role of nuclear factor-κB activation in metalloproteinase-1, -3, and -9 secretion by human macrophages in vitro and rabbit foam cells produced in vivo. Arteriosclerosis, Thrombosis, and Vascular Biology 22 5 (2002) 765-771
6. Chen H.C., Appeddu P.A., Isada H., and Guan J.L. Phosphorylation of tyrosine 397 in focal adhesion kinase is required for binding phosphatidylinositol 3-kinase. The Journal of Biological Chemistry 271 42 (1996) 26329-26334
7. Deryugina E.I., and Quigly J.P. Matrix metalloproteinases and tumour metastasis. Cancer and Metastasis Reviews 25 1 (2006) 9-34
8. Dudley D.T., Pang L., Decker S.J., Bridges A.J., and Saltiel A.R. A synthetic inhibitor of the mitogen-activated protein kinase cascade. Proceedings of the National Academy of Sciences of the United States of America 92 17 (1995) 7686-7689
9. Esparza J., Vilardell C., Calvo J., Juan M., Vives J., Urbano-Marquez A., Yague J., and Cid M.C. Fibronectin upregulates gelatinase B (MMP-9) and induces coordinated expression of gelatinase A (MMP-2) and its activator MT1-MMP (MMP-14) by human T lymphocyte cell lines. A process repressed through RAS/MAP kinase signaling pathways. Blood 94 8 (1999) 2754-2766
10. Gong J., Wang D., Sun L., Zborowska E., Wilson J.K.V., and Brattain M.G. Role of alpha5 beta1 integrin in determining malignant properties of colon carcinoma cells. Cell Growth and Differentiation 8 1 (1997) 83-90
11. Hofmann U.B., Westphal J.R., van Kraats A.A., Ruiter D.J., and van Muijen G.N.P. Expression of integrin alpha(v)beta(3) correlates with activation of membrane-type matrix metalloproteinase-1 (MT1-MMP) and matrix metalloproteinase-2 (MMP-2) in human melanoma cells in vitro and in vivo. International Journal of Cancer; 87 1 (2000) 12-19
12. Jia Y., Zeng Z.Z., Markwart S.M., Rockwood K.F., Ignatoshi K.M.W., Ethier S.P., and Livant D.L. Integrin fibronectin receptors in matrix metalloproteinase-1-dependent invasion by breast cancer and mammary epithelial cells. Cancer Research 64 23 (2004) 8674-8681
13. Juliano R.L. Signal transduction by cell adhesion receptors and the cytoskeleton: Functions of integrins, cadherins, selectins, and immunoglobulin-superfamily members. Annual Review of Pharmacology and Toxicology 42 (2002) 283-323
14. Kaspar M., Zardi L., and Neri D. Fibronectin as target for tumour therapy. International Journal of Cancer 118 6 (2006) 1331-1339
15. Kazes I., Elalamy I., Sraer J.D., Hatmi M., and Nguyen G. Platelet release of trimolecular complex components MT1-MMP/TIMP2/MMP2: involvement in MMP2 activation and platelet aggregation. Blood 96 9 (2000) 3064-3069
16. Khwaja A., Rodriguez-Viciano P., Weinstrom S., Warne P.H., and Downward J. Matrix adhesion and Ras transformation both activate a phosphoinositide 3-OH kinase and protein kinase B/Akt cellular survival pathway. The EMBO Journal 16 10 (1997) 2783-2793
17. Koshikawa N., Minegishi T., Sharabi A., Quaranta V., and Seiki M. Membrane-type matrix metalloproteinase-1 (MT1-MMP) is a processing enzyme for human laminin gamma 2 chain. The Journal of Biological Chemistry 280 1 (2005) 88-93
18. Kurschat P., Zigrino P., Nischt R., Breitkopf K., Steurer P., Klein C.E., Krieg T., and Mauch C. Tissue inhibitor of matrix metalloproteinase-2 regulates matrix metalloproteinase-2 activation by modulation of membrane-type 1 matrix metalloproteinase activity in high and low invasive melanoma cell lines. The Journal of Biological Chemistry 274 30 (1999) 21056-21062
19. Laemmli U.K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227 5259 (1970) 680-685
20. Lenormand P., Sardet C., Pages G., L'Allemain G., Brunet A., and Pouyssegur J. Growth factors induce nuclear translocation of MAP kinases (p42mapk and p44mapk) but not of their activator MAP kinase kinase (p45mapkk) in fibroblasts. The Journal of Cell Biology 122 5 (1993) 1079-1088
21. Lehti K., Lohi J., Valtanen H., and Keshi-oja J. Proteolytic processing of membrane-type-1 matrix metalloproteinase is associated with gelatinase A activation at the cell surface. The Biochemical Journal 334 2 (1998) 345-353
22. Mitra A., Chakrabarti J., Banerji A., and Chatterjee A. Binding of alpha2 monoclonal antibody to human cervical tumor cell (SiHa) surface alpha2 beta1 integrin modulates MMP-2 activity. Gynecologic Oncology 94 1 (2004) 33-39
23. Mitra A., Chakrabarti J., and Chatterjee A. Binding of alpha5 monoclonal antibody to cell surface alpha5 beta1 integrin modulates MMP-2 and MMP-7 activity in B16F10 melanoma cells. Journal of Environmental Pathology Toxicology and Oncology 22 3 (2003) 167-178
24. Mitra A., Chakrabarti J., Banerji A., Das S., and Chatterjee A. Culture of human cervical cancer cells in presence of fibronectin activates MMP-2. Journal of Cancer Research and Clinical Oncology 132 8 (2006) 505-513
25. Munshi H.G., and Starck M.S. Reciprocal interaction between adhesion receptor signalling and MMP regulation. Cancer and Metastasis Reviews 25 1 (2006) 45-56
26. Munshi H.G., Wu Y.I., Mukhopadhyay S., Ottaviano A.J., Sassano A., Koblinski J.E., Plantanias L.C., and Stack M.S. Differential regulation of membrane type 1-matrix metalloproteinase activity by ERK 1/2- and p38 MAPK-modulated tissue inhibitor of metalloproteinases 2 expression controls transforming growth factor-beta1-induced pericellular collagenolysis. The Journal of Biological Chemistry 279 37 (2004) 39042-39050
27. Ratnikov B.I., Rozanov D.V., Postnova T.I., Baciu P.G., Zhang H., DiScipio R.G., Chestukhina G.G., Smith J.W., Deryugina E.I., and Strongin A.Y. An alternative processing of integrin αv subunit in tumor cells by membrane type-1 matrix metalloproteinase. The Journal of Biological Chemistry 277 9 (2002) 7377-7385
28. Rolli M., Fransvea E., Jan P., Saven A., and Felding-Habermenn B. Activated integrin alphav beta3 cooperates with metalloproteinase MMP-9 in regulating migration of metastatic breast cancer cells. Proceedings of the National Academy of Sciences of the United States of America 100 16 (2003) 9482-9487
29. Samuels Y., and Erickson K. Oncogenic PI3K and its role in cancer. Current Opinions in Oncology 18 1 (2006) 77-82
30. Sato H., Takino T., Okada Y., Cao J., Shinagawa A., Yamamoto E., and Seiki M. Matrix metalloproteinase expressed on the surface of invasive tumour cells. Nature 370 6484 (1994) 61-65
31. Seftor R.E., Seftor E.A., Stetler-Stevenson W.G., and Hendrix M.J. The 72 kDa type IV collagenase is modulated via differential expression of alpha v beta 3 and alpha 5 beta 1 integrins during human melanoma cell invasion. Cancer Research 53 14 (1993) 3411-3415
32. Seftor R.E., Seftor E.A., Gehlsen K.R., Stetler-Stevenson W.G., Brown P.D., Rouslahti E., and Hendrix M.J. Role of the alpha v beta 3 integrin in human melanoma cell invasion. Proceedings of the National Academy of Sciences of the United States of America 89 5 (1992) 1557-1561
33. Stanton H., Gavrilovic J., Atkinson S.J., d'Ortho M.P., Yamada K.M., Zardi L., and Murphy G. The activation of proMMP-2 (gelatinase A) by HT-1080 fibrosarcoma cells is promoted by culture on a fibronectin substrate and is concomitant with an increase in processing of MT1-MMP (MMP-14) to a 45 kDa form. Journal of Cell Science 111 18 (1998) 2789-2798
34. Stygar D., Wang H., Vladic Y.S., Ekman G., Eriksson H., and Shalin L. Increased level of matrix metalloproteinases 2 and 9 in the ripening process of the human cervix. Biology of Reproduction 67 3 (2002) 889-894
35. Thant A.A., Nawa A., Kikkawa F., Ichigotani Y., Zhang Y., Sein T.T., Amin A.R., and Hamaguchi M. Fibronectin activates matrix metalloproteinase-9 secretion via the MEK1-MAPK and the PI-3K-Akt pathways in ovarian cancer cells. Clinical & Experimental Metastasis; 18 5 (2000) 423-428
36. Tokuraku M., Sato H., Murrakami S., Okada Y., Watanabe Y., and Seiki M. Activation of the precursor of gelatinase A/72 kDa type IV collagenase/MMP-2 in lung carcinomas correlates with the expression of membrane-type matrix metalloproteinase (MT-MMP) and with lymph node metastasis. International Journal of Cancer 64 5 (1995) 355-359
37. Toth M., and Fridman R. Assessment of gelatinases (MMP-2 and MMP-9) by gelatin zymography. In: Brooks S.A., and Schumacher U. (Eds). Metastasis Research Protocols vol. 1 (2001), Humana Press, Totawa, New Jersey 163-178
38. Ueno H., Nakamura H., Inoue M., Imai K., Naguchi M., Sato H., Seiki M., and Okoda Y. Expression and tissue localization of membrane-types 1, 2, and 3 matrix metalloproteinases in human invasive breast carcinomas. Cancer Research 57 10 (1997) 2055-2060
39. Unemori E.N., and Werb Z. Reorganization of polymerized actin: a possible trigger for induction of procollagenase in fibroblasts cultured in and on collagen gels. The Journal of Cell Biology 103 3 (1986) 1021-1031
40. Van den Steen P.E., Dubois B., Nelissen I., Rudd P.M., Dwek R.A., and Opdenakker G. Biochemistry and molecular biology of gelatinase B or matrix metalloproteinase-9 (MMP-9). Critical Reviews in Biochemistry and Molecular Biology 37 6 (2002) 375-536
41. Vlahos C.J., Matter W.F., Hui K.Y., and Brown R.F. A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002). The Journal of Biological Chemistry 269 7 (1994) 5241-5248
42. Visse R., and Nagase H. Matrix metalloproteinases and tissue inhibitors of metalloproteinases: structure, function, and biochemistry. Circulation Research 92 8 (2003) 827-839
43. Wong H., Muzik H., Groft L.L., Lafleur M.A., Matouk C., Forsyth P.A., Schultz G.A., Wall S.J., and Edwards D.R. Monitoring MMP and TIMP mRNA expression by RT-PCR. In: Clark I.M. (Ed). Matrix Metalloproteinase Protocols (2001), Humana Press, Totowa, New Jersey 305-320
44. Zhang J., Zhi H., Zhou C., Ding F., Luo A., Zhang X., Sun Y., Whang X., Wu M., and Liu Z. Up-regulation of fibronectin in oesophageal squamous cell carcinoma is associated with activation of the Erk pathway. The Journal of Pathology 207 4 (2005) 402-409
45. Zucker S., Hymowitz M., Conner C., DeClerk Y., and Cao J. TIMP-2 is released as an intact molecule following binding to MT1-MMP on the cell surface. Experimental Cell Research 293 1 (2004) 164-174