Neuregulin 1-alpha expression in locally advanced breast cancer

Breast

Volumn 10, Issue 1, 2001, Pages 41-45

  Raj, E H ^a   Skinner, A ^a   Mahji, U ^a   Nirmala, K N ^a   Ravichandran, K ^a   Shanta, V ^a   Hurst, H C ^a   Gullick, W J ^a   Rajkumar, T ^a  

^a UNIVERSITY OF KENT   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIESTROGEN; ANTINEOPLASTIC AGENT; CYCLOPHOSPHAMIDE; FLUOROURACIL; GROWTH FACTOR RECEPTOR; ISOPROTEIN; LIGAND; METHOTREXATE; NEU DIFFERENTIATION FACTOR; NEU DIFFERENTIATION FACTOR 1 ALPHA; POLYCLONAL ANTIBODY; SYNTHETIC PEPTIDE; TAMOXIFEN; TYROSINE KINASE RECEPTOR; UNCLASSIFIED DRUG;

ADULT; ADVANCED CANCER; AGED; ALTERNATIVE RNA SPLICING; ARTICLE; BREAST ADENOCARCINOMA; CANCER ADJUVANT THERAPY; CANCER RADIOTHERAPY; CANCER SURVIVAL; COMPARATIVE STUDY; CONTROLLED STUDY; FEMALE; HUMAN; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; MASTECTOMY; ONCOGENE C ERB; PRIORITY JOURNAL; PROGNOSIS; PROTEIN EXPRESSION;

EID: 0035141107     PISSN: 09609776     EISSN: None     Source Type: Journal    
DOI: 10.1054/brst.2000.0182     Document Type: Article

References (23)

1. Identification of Heregulin, a specific activator of p185erbB2
2. Heregulin induces tyrosine phosphorylation of HER4/p 180erbB4
3. The erbB3 gene product is a receptor for Heregulin
4. NDF Heregulin stimulates the phosphorylation of HER3/erbB3
5. Neural expression and chromosomal mapping of neu differentiation factor to 8p12-p21
6. Glial growth factors are alternatively spliced erbB2 ligands expressed in the nervous system
7. Ligands for Erb-B family receptors encoded by a neuregulin-like gene
8. Neuregulin-2, a new ligand of ErbB3/ErbB4-receptor tyrosine kinases
9. Characterisation of a Neuregulin-related gene, Don-1, that is highly expressed is restricted regions of the cerebellum and hippocampus
10. A novel brain derived member of the epidermal growth factor family that interacts with ErbB3 and ErbB4
11. Neuregulin 3 (NRG3): A novel neural tissue-enriched protein that binds and activates ErbB4
12. Cell-type specific interaction of neu differentiation factor (NDF/Heregulin) with neu/HER2 suggests complex ligand-receptor relationships
13. Structural and functional aspects of the multiplicity of neu differentiation factors
14. Co-expression of erbB2 and erbB3 proteins reconstitutes a high affinity receptor for Heregulin
15. Cancer incidence and mortality in Madras, India Madras Metropolitan Tumour Registry
16. The production of antibodies to growth factor receptors using synthetic peptides as immunogens
17. Expression of the c-erbB3 protein in normal human adult and fetal tissues
18. Transforming growth factor alpha production and epidermal growth factor receptor expression in normal and oncogene transformed human mammary epithelial cells
19. Immunoreactive alpha transforming growth factor activity in effusions from cancer patients as a marker of tumour burden and patient prognosis
20. Regulation of proliferation and differentiation of normal and malignant breast: New factors and neu paradoxes
21. Multiple effects of neu differentiation factor on schwann cell function
22. Brain neurons and glial cells express neu differentiation factor/heregulin: A survival factor for astrocytes
23. Loss of Heregulin expression is associated with malignancy