-
1
-
-
0028023828
-
Association of Hsp90 with cellular Src-family kinases in a cell-free system correlates with altered kinase structure and function
-
Hartson SD, Matts RL. Association of Hsp90 with cellular Src-family kinases in a cell-free system correlates with altered kinase structure and function. Biochemistry 1994;33:8912-20.
-
(1994)
Biochemistry
, vol.33
, pp. 8912-8920
-
-
Hartson, S.D.1
Matts, R.L.2
-
3
-
-
0028786332
-
Disruption of the Raf-1-Hsp90 molecular complex results in destabilization of Raf-1 and loss of Raf-1-Ras association
-
Schulte TW, Blagosklonny MV, Ingui C, Neckers L. Disruption of the Raf-1-Hsp90 molecular complex results in destabilization of Raf-1 and loss of Raf-1-Ras association. J Biol Chem 1995;270:24585-8.
-
(1995)
J Biol Chem
, vol.270
, pp. 24585-24588
-
-
Schulte, T.W.1
Blagosklonny, M.V.2
Ingui, C.3
Neckers, L.4
-
4
-
-
0033724701
-
Chaperones in cell cycle regulation and mitogenic signal transduction: A review
-
Helmbrecht K, Zeise E, Rensing L. Chaperones in cell cycle regulation and mitogenic signal transduction: a review. Cell Prolif 2000;33:341-65.
-
(2000)
Cell Prolif
, vol.33
, pp. 341-365
-
-
Helmbrecht, K.1
Zeise, E.2
Rensing, L.3
-
5
-
-
0030989277
-
Folding of the glucocorticoid receptor by the reconstituted Hsp90-based chaperone machinery. The initial hsp90.p60.hsp70- dependent step is sufficient for creating the steroid binding conformation
-
Dittmar KD, Pratt WB. Folding of the glucocorticoid receptor by the reconstituted Hsp90-based chaperone machinery. The initial hsp90.p60.hsp70- dependent step is sufficient for creating the steroid binding conformation. J Biol Chem 1997;272:13047-54.
-
(1997)
J Biol Chem
, vol.272
, pp. 13047-13054
-
-
Dittmar, K.D.1
Pratt, W.B.2
-
6
-
-
0024970241
-
r approximately 90,000 heat shock protein: An important modulator of ligand and DNA-binding properties of the glucocorticoid receptor
-
s
-
r approximately 90,000 heat shock protein: an important modulator of ligand and DNA-binding properties of the glucocorticoid receptor. Cancer Res 1989;49:2275-81s.
-
(1989)
Cancer Res
, vol.49
, pp. 2275-2281
-
-
Denis, M.1
Gustafsson, J.A.2
-
7
-
-
20044384168
-
Phase I trial of 17-allylamino-17- demethoxygeldanamycin in patients with advanced cancer
-
Goetz MP, Toft D, Reid J, et al. Phase I trial of 17-allylamino-17- demethoxygeldanamycin in patients with advanced cancer. J Clin Oncol 2005;23:1078-87.
-
(2005)
J Clin Oncol
, vol.23
, pp. 1078-1087
-
-
Goetz, M.P.1
Toft, D.2
Reid, J.3
-
9
-
-
0033502429
-
Geldanamycin as a potential anti-cancer agent: Its molecular target and biochemical activity
-
Neckers L, Schulte TW, Mimnaugh E. Geldanamycin as a potential anti-cancer agent: its molecular target and biochemical activity. Invest New Drugs 1999;17:361-73.
-
(1999)
Invest New Drugs
, vol.17
, pp. 361-373
-
-
Neckers, L.1
Schulte, T.W.2
Mimnaugh, E.3
-
10
-
-
0035989680
-
HSP90 as a new therapeutic target for cancer therapy: The story unfolds
-
Maloney A, Workman P. HSP90 as a new therapeutic target for cancer therapy: the story unfolds. Expert Opin Biol Ther 2002;2:3-24.
-
(2002)
Expert Opin Biol Ther
, vol.2
, pp. 3-24
-
-
Maloney, A.1
Workman, P.2
-
11
-
-
0036919003
-
Pharmacogenomics in cancer drug discovery and development: Inhibitors of the Hsp90 molecular chaperone
-
Workman P. Pharmacogenomics in cancer drug discovery and development: inhibitors of the Hsp90 molecular chaperone. Cancer Detect Prev 2002;26:405-10.
-
(2002)
Cancer Detect Prev
, vol.26
, pp. 405-410
-
-
Workman, P.1
-
12
-
-
0043288724
-
Heat shock protein 90 as a molecular target for cancer therapeutics
-
Isaacs JS, Xu W, Neckers L. Heat shock protein 90 as a molecular target for cancer therapeutics. Cancer Cell 2003;3:213-7.
-
(2003)
Cancer Cell
, vol.3
, pp. 213-217
-
-
Isaacs, J.S.1
Xu, W.2
Neckers, L.3
-
13
-
-
20144375312
-
Phase I and pharmacologic study of 17-(allylamino)-17-demethoxygeldanamycin in adult patients with solid tumors
-
Grem JL, Morrison G, Guo XD, et al. Phase I and pharmacologic study of 17-(allylamino)-17-demethoxygeldanamycin in adult patients with solid tumors. J Clin Oncol 2005;23:1885-93.
-
(2005)
J Clin Oncol
, vol.23
, pp. 1885-1893
-
-
Grem, J.L.1
Morrison, G.2
Guo, X.D.3
-
14
-
-
23044441106
-
Phase I pharmacokinetic and pharmacodynamic study of 17-allylamino, 17-demethoxygeldanamycin in patients with advanced malignancies
-
Banerji U, O'Donnell A, Scurr M, et al. Phase I pharmacokinetic and pharmacodynamic study of 17-allylamino, 17-demethoxygeldanamycin in patients with advanced malignancies. J Clin Oncol 2005;23:4152-61.
-
(2005)
J Clin Oncol
, vol.23
, pp. 4152-4161
-
-
Banerji, U.1
O'Donnell, A.2
Scurr, M.3
-
15
-
-
0042885973
-
The Hsp90 chaperone complex as a novel target for cancer therapy
-
Goetz MP, Toft DO, Ames MM, Erlichman C. The Hsp90 chaperone complex as a novel target for cancer therapy. Ann Oncol 2003;14:1169-76.
-
(2003)
Ann Oncol
, vol.14
, pp. 1169-1176
-
-
Goetz, M.P.1
Toft, D.O.2
Ames, M.M.3
Erlichman, C.4
-
16
-
-
20944444881
-
Phase I pharmacokinetic- pharmacodynamic study of 17-(allylamino)-17-demethoxygeldanamycin (17AAG, NSC 330507), a novel inhibitor of heat shock protein 90, in patients with refractory advanced cancers
-
Ramanathan RK, Trump DL, Eiseman JL, et al. Phase I pharmacokinetic- pharmacodynamic study of 17-(allylamino)-17-demethoxygeldanamycin (17AAG, NSC 330507), a novel inhibitor of heat shock protein 90, in patients with refractory advanced cancers. Clin Cancer Res 2005;11:3385-91.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 3385-3391
-
-
Ramanathan, R.K.1
Trump, D.L.2
Eiseman, J.L.3
-
17
-
-
0027468061
-
Identification of a novel neuron-specific surface antigen in the developing nervous system, by monoclonal antibody 4C5
-
Thomaidou D, Patsavoudi E. Identification of a novel neuron-specific surface antigen in the developing nervous system, by monoclonal antibody 4C5. Neuroscience 1993;53:813-27.
-
(1993)
Neuroscience
, vol.53
, pp. 813-827
-
-
Thomaidou, D.1
Patsavoudi, E.2
-
18
-
-
8544274533
-
Involvement of cell surface HSP90 in cell migration reveals a novel role in the developing nervous system
-
Sidera K, Samiotaki M, Yfanti E, Panayotou G, Patsavoudi E. Involvement of cell surface HSP90 in cell migration reveals a novel role in the developing nervous system. J Biol Chem 2004;279:45379-88.
-
(2004)
J Biol Chem
, vol.279
, pp. 45379-45388
-
-
Sidera, K.1
Samiotaki, M.2
Yfanti, E.3
Panayotou, G.4
Patsavoudi, E.5
-
19
-
-
0031708735
-
Migration behavior of rodent granule neurons in the presence of antibody to the 4C5 antigen
-
Yfanti E, Nagata I, Patsavoudi E. Migration behavior of rodent granule neurons in the presence of antibody to the 4C5 antigen. J Neurochem 1998;71:1381-9.
-
(1998)
J Neurochem
, vol.71
, pp. 1381-1389
-
-
Yfanti, E.1
Nagata, I.2
Patsavoudi, E.3
-
20
-
-
0346655316
-
The 4C5 antigen is associated with Schwann cell migration during development and regeneration of the rat peripheral nervous system
-
Yfanti E, Sidera K, Margaritis LH, Patsavoudi E. The 4C5 antigen is associated with Schwann cell migration during development and regeneration of the rat peripheral nervous system. Glia 2004;45:39-53.
-
(2004)
Glia
, vol.45
, pp. 39-53
-
-
Yfanti, E.1
Sidera, K.2
Margaritis, L.H.3
Patsavoudi, E.4
-
21
-
-
0028961891
-
Developmental expression and functional characterization of the 4C5 antigen in the postnatal cerebellar cortex
-
Thomaidou D, Dori I, Patsavoudi E. Developmental expression and functional characterization of the 4C5 antigen in the postnatal cerebellar cortex. J Neurochem 1995;64:1937-44.
-
(1995)
J Neurochem
, vol.64
, pp. 1937-1944
-
-
Thomaidou, D.1
Dori, I.2
Patsavoudi, E.3
-
22
-
-
0842329639
-
Induction of Hsp90 protein expression in malignant melanomas and melanoma metastases
-
Becker B, Multhoff G, Farkas B, et al. Induction of Hsp90 protein expression in malignant melanomas and melanoma metastases. Exp Dermatol 2004;13:27-32.
-
(2004)
Exp Dermatol
, vol.13
, pp. 27-32
-
-
Becker, B.1
Multhoff, G.2
Farkas, B.3
-
23
-
-
0022458323
-
Monoclonal antibodies specific for melanocytic tumors distinguish subpopulations of melanocytes
-
Gown AM, Vogel AM, Hoak D, Gough F, McNutt MA. Monoclonal antibodies specific for melanocytic tumors distinguish subpopulations of melanocytes. Am J Pathol 1986;123:195-203.
-
(1986)
Am J Pathol
, vol.123
, pp. 195-203
-
-
Gown, A.M.1
Vogel, A.M.2
Hoak, D.3
Gough, F.4
McNutt, M.A.5
-
24
-
-
0025810812
-
Substrate dependent pH optima of gp63 purified from seven strains of Leishmania
-
Tzinia A, Soteriadou KP. Substrate dependent pH optima of gp63 purified from seven strains of Leishmania. Mol Biochem Parasitol 1991;47:83-9.
-
(1991)
Mol Biochem Parasitol
, vol.47
, pp. 83-89
-
-
Tzinia, A.1
Soteriadou, K.P.2
-
25
-
-
2942716692
-
Functional proteomic screens reveal an essential extracellular role for hsp90α in cancer cell invasiveness
-
Eustace BK, Sakurai T, Stewart JK, et al. Functional proteomic screens reveal an essential extracellular role for hsp90α in cancer cell invasiveness. Nat Cell Biol 2004;6:507-14.
-
(2004)
Nat Cell Biol
, vol.6
, pp. 507-514
-
-
Eustace, B.K.1
Sakurai, T.2
Stewart, J.K.3
-
26
-
-
21144432950
-
The heat shock protein 90 inhibitor, 17-allylamino-17-demethoxygeldanamycin, enhances osteoclast formation and potentiates bone metastasis of a human breast cancer cell line
-
Price JT, Quinn JMW, Sims NA, et al. The heat shock protein 90 inhibitor, 17-allylamino-17-demethoxygeldanamycin, enhances osteoclast formation and potentiates bone metastasis of a human breast cancer cell line. Cancer Res 2005;65:4929-38.
-
(2005)
Cancer Res
, vol.65
, pp. 4929-4938
-
-
Price, J.T.1
Quinn, J.M.W.2
Sims, N.A.3
-
27
-
-
18844396087
-
Potent activity of a novel dimeric heat shock protein 90 inhibitor against head and neck squamous cell carcinoma in vitro and in vivo
-
Yin X, Zhang H, Burrows F, Zhang L, Shores CG. Potent activity of a novel dimeric heat shock protein 90 inhibitor against head and neck squamous cell carcinoma in vitro and in vivo. Clin Cancer Res 2005;11:3889-96.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 3889-3896
-
-
Yin, X.1
Zhang, H.2
Burrows, F.3
Zhang, L.4
Shores, C.G.5
-
28
-
-
33645470397
-
Benzoquinone ansamycin heat shock protein 90 inhibitors modulate multiple functions required for tumor angiogenesis
-
Sanderson S, Valenti M, Gowan S, et al. Benzoquinone ansamycin heat shock protein 90 inhibitors modulate multiple functions required for tumor angiogenesis. Mol Cancer Ther 2006;5:522-32.
-
(2006)
Mol Cancer Ther
, vol.5
, pp. 522-532
-
-
Sanderson, S.1
Valenti, M.2
Gowan, S.3
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