Recent advances in tumor-targeting anticancer drug conjugates

Bioorganic and Medicinal Chemistry

Volumn 13, Issue 17, 2005, Pages 5043-5054

  Jaracz, Stanislav ^a   Chen, Jin ^a   Kuznetsova, Larisa V ^a   Ojima, Iwao ^a  

^a STONY BROOK UNIVERSITY   (United States)

Author keywords

Chemotherapy; Conjugate; Cytotoxic; Drug delivery; Folic acid; Hyaluronic acid; Liposome; Monoclonal antibody; Polyunsaturated fatty acids; Tumor targeting

Indexed keywords

ANTIBODY CONJUGATE; ANTINEOPLASTIC AGENT; CYTOTOXIC AGENT; DOXORUBICIN; ESSENTIAL FATTY ACID; GEMTUZUMAB OZOGAMICIN; HERMES ANTIGEN; HYALURONIC ACID; LIPOSOME; MITOMYCIN C; MONOCLONAL ANTIBODY; PACLITAXEL; PACLITAXEL DERIVATIVE; POLYUNSATURATED FATTY ACID; TAXOPREXIN;

ACUTE GRANULOCYTIC LEUKEMIA; ANTIGEN BINDING; ANTIGEN EXPRESSION; ANTINEOPLASTIC ACTIVITY; CANCER CELL; CANCER GROWTH; DISULFIDE BOND; DRUG CYTOTOXICITY; DRUG DELIVERY SYSTEM; DRUG TARGETING; ESTERIFICATION; HYBRIDOMA; IC 50; LEUKEMIA CELL; MELANOMA CELL; MOLECULAR WEIGHT; REVIEW; TARGET CELL DESTRUCTION;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTINEOPLASTIC AGENTS; FATTY ACIDS, UNSATURATED; HUMANS; HYALURONIC ACID; IMMUNOCONJUGATES; NEOPLASMS;

EID: 22844436226     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2005.04.084     Document Type: Review

References (126)

1. H. Maeda, J. Fang, T. Inutsuka, and Y. Kitamoto Int. Immunopharmacol. 3 2003 319
2. H. Maeda, Y. Matsumura, T. Oda, and K. Sasamoto R.E. Feeny J.R. Whitaker Protein Tailoring for Food and Medical Uses 1986 Marcel Dekker New York 353 382
3. J.R. Griffiths Br. J. Cancer 64 1991 425
4. P.A. Schornack, and R.J. Gillies Neoplasia 5 2003 135
5. C.N. Liu, B.M. Tadayoni, L.A. Bourret, K.M. Mattocks, S.M. Derr, W.C. Widdison, N.L. Kedersha, P.D. Ariniello, V.S. Goldmacher, J.M. Lambert, W.A. Blattler, and R.V.J. Chari Proc. Natl. Acad. Sci. U.S.A. 93 1996 8618
6. R.V.J. Chari Adv. Drug Deliv. Rev. 31 1998 89
7. R.V.J. Chari, K.A. Jackel, L.A. Bourret, S.M. Derr, B.M. Tadayoni, K.M. Mattocks, S.A. Shah, C.N. Liu, W.A. Blattler, and V.S. Goldmacher Cancer Res. 55 1995 4079
8. P. Ehrlich F. Himmelweit M. Marquardt H. Dale Immunology and Cancer Research Vol. 2 1956 Pergamon London 442 447
9. D. Papachristou, A.F. Zaki, and J.G. Fortner Transplant. Proc. 9 1977 1059
10. G. Kohler, and C. Milstein Nature 256 1975 495
11. P.R. Hamann, L.M. Hinman, I. Hollander, C.F. Beyer, D. Lindh, R. Holcomb, W. Hallett, H.R. Tsou, J. Upeslacis, D. Shochat, A. Mountain, D.A. Flowers, and I. Bernstein Bioconjugate Chem. 13 2002 47
12. L. Lam, C. Lam, W.H. Li, and Y. Cao Drug Future 28 2003 905
13. M.N. Saleh, A.F. LoBuglio, and P.A. Trail Basic Clin. Oncol. 15 1998 397
14. S.Y. Chan, A.N. Gordon, R.E. Coleman, J.B. Hall, M.S. Berger, M.L. Sherman, C.B. Eten, and N.J. Finkler Cancer Immunol. Immunother. 52 2003 243
15. A.M. Gillespie, T.J. Broadhead, S.Y. Chan, J. Owen, A.P. Farnsworth, M. Sopwith, and R.E. Coleman Ann. Oncol. 11 2000 735
16. P. Carter Nat. Rev. Cancer 1 2001 118
17. M.A. Roguska, J.T. Pedersen, A.H. Henry, S.M.J. Searle, C.M. Roja, B. Avery, M. Hoffee, S. Cook, J.M. Lambert, W.A. Blattler, A.R. Rees, and B.C. Guild Protein Eng. 9 1996 895
18. Y. Hansson, S. Paulie, H. Benaissa, U. Rudberg, A. Karlsson, and P. Perlmann Anticancer Res. 8 1988 435
19. E. Otsuji, T. Yamaguchi, H. Tsuruta, Y. Yata, H. Nishi, K. Okamoto, K. Taniguchi, M. Kato, T. Kotani, K. Kitamura, and T. Takahashi Br. J. Cancer 73 1996 1178
20. K.J. Hamblett, P.D. Senter, D.F. Chace, M.M.C. Sun, J. Lenox, C.G. Cerveny, K.M. Kissler, S.X. Bernhardt, A.K. Kopcha, R.F. Zabinski, D.L. Meyer, and J.A. Francisco Clin. Cancer Res. 10 2004 7063
21. Y. Manabe, T. Tsubota, Y. Haruta, K. Kataoka, M. Okazaki, S. Haisa, K. Nakamura, and I. Kimura Biochem. Pharmacol. 34 1985 289
22. N. Endo, Y. Takeda, K. Kishida, Y. Kato, M. Saito, N. Umemoto, and T. Hara Cancer Immunol. Immunother. 25 1987 1
23. M.E. Spearman, R.M. Goodwin, L.D. Apelgren, and T.F. Bumol J. Pharmacol. Exp. Ther. 241 1987 695
24. L.D. Apelgren, D.L. Zimmerman, S.L. Briggs, and T.F. Bumol Cancer Res. 50 1990 3540
25. S.O. Doronina, B.E. Toki, M.Y. Torgov, B.A. Mendelsohn, C.G. Cerveny, D.F. Chace, R.L. DeBlanc, R.P. Gearing, T.D. Bovee, C.B. Siegall, J.A. Francisco, A.F. Wahl, D.L. Meyer, and P.D. Senter Nat. Biotechnol. 21 2003 778
26. I. Ojima, X.D. Geng, X.Y. Wu, C.X. Qu, C.P. Borella, H.S. Xie, S.D. Wilhelm, B.A. Leece, L.M. Bartle, V.S. Goldmacher, and R.V.J. Chari J. Med. Chem. 45 2002 5620
27. A.E. Frankel, D.R. Fleming, B.L. Powell, and R. Gartenhaus Expert Opin. Biol. Ther. 3 2003 179
28. J.G. Ramage, D.A. Vallera, J.H. Black, P.D. Aplan, U.R. Kees, and A.E. Frankel Leuk. Res. 27 2003 79
29. J. Romer, B.S. Nielsen, and M. Ploug Curr. Pharm. Design 10 2004 2359
30. Q. Li, C.F. Verschraegen, J. Mendoza, and R. Hassan Anticancer Res. 24 2004 1327
31. M. Onda, Q.C. Wang, H.F. Guo, N.K.V. Cheung, and I. Pastan Cancer Res. 64 2004 1419
32. D. Bruell, M. Stocker, M. Huhn, N. Redding, M. Kupper, P. Schumacher, A. Paetz, C.J. Bruns, H.J. Haisma, R. Fischer, R. Finnern, and S. Barth Int. J. Oncol. 23 2003 1179
33. X.M. Huang, M. Bennett, and P.E. Thorpe Prostate 61 2004 1
34. A.F. Wahl, K.L. Donaldson, B.J. Mixan, P.A. Trail, and C.B. Siegall Int. J. Cancer 93 2001 590
35. B. Říhová, J. Strohalm, J. Prausová, K. Kubáčková, M. Jelínková, L. Rozprimová, M. Šírová, D. Plocová, T. Etrych, V. Šubr, T. Mrkvan, M. Kovář, and K. Ulbrich J. Controlled Release 91 2003 1
36. P.R. Hamann, L.M. Hinman, C.F. Beyer, D. Lindh, J. Upeslacis, D.A. Flowers, and I. Bernstein Bioconjugate Chem. 13 2002 40
37. T. Kaneko, D. Willner, I. Monkovic, J.O. Knipe, G.R. Braslawsky, R.S. Greenfield, and D.M. Vyas Bioconjugate Chem. 2 1991 133
38. P. Rejmanova, J. Kopecek, R. Duncan, and J.B. Lloyd Biomaterials 6 1985 45
39. G.M. Dubowchik, R.A. Firestone, L. Padilla, D. Willner, S.J. Hofstead, K. Mosure, J.O. Knipe, S.J. Lasch, and P.A. Trail Bioconjugate Chem. 13 2002 855
40. A.A. Sinha, M.P. Jamuar, M.J. Wilson, J. Rozhin, and B.F. Sloane Prostate 49 2001 172
41. J. Kigawa, Y. Minagawa, Y. Kanamori, H. Itamochi, X.S. Cheng, M. Okada, T. Oishi, and N. Terakawa Cancer 82 1998 697
42. A.W. Tolcher, L. Ochoa, L.A. Hammond, A. Patnaik, T. Edwards, C. Takimoto, L. Smith, J. de Bono, G. Schwartz, T. Mays, Z.L. Jonak, R. Johnson, M. DeWitte, H. Martino, C. Audette, K. Maes, R.V.J. Chari, J.M. Lambert, and E.K. Rowinsky J. Clin. Oncol. 21 2003 211
43. A. Tolcher, B. Forouzesh, H. McCreery, R. Zinner, Y. Clinch, R. Barrington, J. Lambert, M. Howard, E. Rowinsky, and F. Fossella Eur. J. Cancer 38 2002 S152
44. M. Ranson, and M.X. Sliwkowski Oncology 63 2002 17
45. H. Tapiero, G.N. Ba, P. Couvreur, and K.D. Tew Biomed. Pharmacother. 56 2002 215
46. W.E. Hardman J. Nutr. 132 2002 3508S
47. S.J. Wigmore, J.A. Ross, J.S. Falconer, C.E. Plester, M.J. Tisdale, D.C. Carter, and K.C.H. Fearon Nutrition 12 1996 S27
48. R.A. Hawkins, K. Sangster, and M.J. Arends J. Pathol. 185 1998 61
49. L.A. Sauer, and R.T. Dauchy Br. J. Cancer 66 1992 297
50. L.A. Sauer, W.O. Nagel, R.T. Dauchy, L.A. Miceli, and J.E. Austin Cancer Res. 46 1986 3469
51. M. Takahashi, M. Przetakiewicz, A. Ong, C. Borek, and J.M. Lowenstein Cancer Res. 52 1992 154
52. S.I. Grammatikos, P.V. Subbaiah, T.A. Victor, and W.M. Miller Br. J. Cancer 70 1994 219
53. L. Diomede, F. Colotta, B. Piovani, F. Re, E.J. Modest, and M. Salmona Int. J. Cancer 53 1993 124
54. T. Sasaki, Y. Tsukada, H.F. Deutsch, and H. Hirai Cancer Chemother. Pharmacol. 13 1984 75
55. Y.J. You, Y. Kim, N.H. Nam, and B.Z. Ahn Bioorg. Med. Chem. Lett. 13 2003 2629
56. M.O. Bradley, N.L. Webb, F.H. Anthony, P. Devanesan, P.A. Witman, S. Hemamalini, M.C. Chander, S.D. Baker, L.F. He, S.B. Horwitz, and C.S. Swindell Clin. Cancer Res. 7 2001 3229
57. Ernstoff, M. S. Norris Cotton Cancer Center 2003, http://www.cancer. dartmouth.edu/clinicaltrials/trials/F0239.shtml
58. M.R. Vredenburg, I. Ojima, J. Veith, P. Pera, K. Kee, F. Cabral, A. Sharma, P. Kanter, W.R. Greco, and R.J. Bernacki J. Nat. Cancer Inst. 93 2001 1234
59. I. Ojima, S.N. Lin, and T. Wang Curr. Med. Chem. 6 1999 927
60. I. Ojima, T. Wang, M.L. Miller, S.N. Lin, C.P. Borella, X.D. Geng, P. Pera, and R. Bernacki J. Bioorg. Med. Chem. Lett. 9 1999 3423
61. S.N. Lin, X.D. Geng, C.X. Qu, R. Tynebor, D.J. Gallagher, E. Pollina, J. Rutter, and I. Ojima Chirality 12 2000 431
62. R. Geney, J. Chen, and I. Ojima Med. Chem. 1 2005 125
63. R.G.W. Anderson, B.A. Kamen, K.G. Rothberg, and S.W. Lacey Science 255 1992 410
64. H. Elnakat, and M. Ratnam Adv. Drug Deliv. Rev. 56 2004 1067
65. S.D. Weitman, R.H. Lark, L.R. Coney, D.W. Fort, V. Frasca, V.R. Zurawski, and B.A. Kamen Cancer Res. 52 1992 3396
66. C. Leuchtenberger, R. Lewisohn, D. Laszlo, and R. Leuchtenberger Proc. Soc. Exp. Biol. Med. 55 1944 204
67. S. Farber, E.C. Cutler, J.W. Hawkins, J.H. Harrison, E.C. Peirce, and G.G. Lenz Science 106 1947 619
68. L. Delmonte, and T.H. Jukes Pharmacol. Rev. 14 1962 91
69. Y.J. Lu, and P.S. Low Adv. Drug Deliv. Rev. 54 2002 675
70. K. Kataoka, A. Harada, and Y. Nagasaki Adv. Drug Deliv. Rev. 47 2001 113
71. A. Gabizon, H. Shmeeda, A.T. Horowitz, and S. Zalipsky Adv. Drug Deliv. Rev. 56 2004 1177
72. B. Rihova Adv. Drug Deliv. Rev. 29 1998 273
73. Y. Hattori, and Y. Maitani J. Controlled Release 97 2004 173
74. J.W. Lee, J.Y. Lu, P.S. Low, and P.L. Fuchs Bioorg. Med. Chem. 10 2002 2397
75. C.A. Ladino, R.V.J. Chari, L.A. Bourret, N.L. Kedersha, and V.S. Goldmacher Int. J. Cancer 73 1997 859
76. C.P. Leamon, and J.A. Reddy Adv. Drug Deliv. Rev. 56 2004 1127
77. D. Goren, A.T. Horowitz, D. Tzemach, M. Tarshish, S. Zalipsky, and A. Gabizon Clin. Cancer Res. 6 2000 1949
78. J. Vaage, E. Mayhew, D. Lasic, and F. Martin Int. J. Cancer 51 1992 942
79. P.J. Stevens, and R.J. Lee Anticancer Res. 23 2003 4927
80. B. Toole E. Hay Cell Biology of the Extracellular Matrix 1982 Plenum Press New York 259 294
81. L. Huang, N. Grammatikakis, M. Yoneda, S.D. Banerjee, and B.P. Toole J. Biol. Chem. 275 2000 29829
82. H. Ponta, L. Sherman, and P.A. Herrlich Nat. Rev. Mol. Cell Biol. 4 2003 33
83. B.P. Toole, T.N. Wight, and M.I. Tammi J. Biol. Chem. 277 2002 4593
84. B. Yang, L. Zhang, and E.A. Turley J. Biol. Chem. 268 1993 8617
85. W.H. McBride, and J.B. Bard J. Exp. Med. 149 1979 507
86. A.J. Day, and G.D. Prestwich J. Biol. Chem. 277 2002 4585
87. E.A. Turley, A.J. Belch, S. Poppema, and L.M. Pilarski Blood 81 1993 446
88. Q. Hua, C.B. Knudson, and W. Knudson J. Cell Sci. 106 1993 365
89. S.J. Green, G. Tarone, and C.B. Underhill Exp. Cell Res. 178 1988 224
90. L. Thomas, H.R. Byers, J. Vink, and I. Stamenkovic J. Cell Biol. 118 1992 971
91. C.B. Knudson J. Cell Biol. 120 1993 825
92. R. Arch, K. Wirth, M. Hofmann, H. Ponta, S. Matzku, P. Herrlich, and M. Zoller Science 257 1992 682
93. R. Kosaki, K. Watanabe, and Y. Yamaguchi Cancer Res. 59 1999 1141
94. N. Liu, F. Gao, Z. Han, X. Xu, C.B. Underhill, and L. Zhang Cancer Res. 61 2001 5207
95. J. Sleeman, S. Arming, J.F. Moll, A. Hekele, W. Rudy, L.S. Sherman, G. Kreil, H. Ponta, and P. Herrlich Cancer Res. 56 1996 3134
96. C. Zeng, B.P. Toole, S.D. Kinney, J. Kuo, and I. Stamenkovic Int. J. Cancer 77 1998 396
97. J. Lesley, V.C. Hascall, M. Tammi, and R. Hyman J. Biol. Chem. 275 2000 26967
98. L. Sherman, J. Sleeman, P. Herrlich, and H. Ponta Curr. Opin. Cell Biol. 6 1994 726
99. M. Takeda, H. Terasawa, M. Sakakura, Y. Yamaguchi, M. Kajiwara, H. Kawashima, M. Miyasaka, and I. Shimada J. Biol. Chem. 278 2003 43550
100. D. Coradini, C. Pellizzaro, G. Miglierini, M.G. Daidone, and A. Perbellini Int. J. Cancer 81 1999 411
101. Y. Luo, and G.D. Prestwich Bioconjugate Chem. 10 1999 755
102. Y. Luo, M.R. Ziebell, and G.D. Prestwich Biomacromolecules 1 2000 208
103. Y. Luo, N.J. Bernshaw, Z.-R. Lu, J. Kopecek, and G.D. Prestwich Pharm. Res. 19 2002 396
104. R.E. Eliaz, and F.C. Szoka Jr. Cancer Res. 61 2001 2592
105. M.N. Pollak, and A.V. Schally Proc. Soc. Exp. Biol. Med. 217 1998 143
106. A.V. Schally Cancer Res. 48 1988 6977
107. C. Orlando, C.C. Raggi, S. Bianchi, V. Distante, L. Simi, V. Vezzosi, S. Gelmini, P. Pinzani, M. Cameron Smith, A. Buonamano, E. Lazzeri, M. Pazzagli, L. Cataliotti, M. Maggi, and M. Serio Endocr. Relat. Cancer 11 2004 323
108. G. Weckbecker, F. Raulf, B. Stolz, and C. Bruns Pharmacol. Ther. 60 1993 245
109. W. Bauer, U. Briner, W. Doepfner, R. Haller, R. Huguenin, P. Marbach, T.J. Petcher, and J. Pless Life Sci. 31 1982 1133
110. L. Buscail, J.P. Esteve, N. Saintlaurent, V. Bertrand, T. Reisine, A.M. Ocarroll, G.I. Bell, A.V. Schally, N. Vaysse, and C. Susini Proc. Natl. Acad. Sci. U.S.A. 92 1995 1580
111. A. Nagy, A.V. Schally, G. Halmos, P. Armatis, R.-Z. Cai, V. Csernus, M. Kovacs, M. Koppan, K. Szepeshazi, and Z. Kahan Proc. Natl. Acad. Sci. U.S.A. 95 1998 1794
112. A. Nagy, A.V. Schally, P. Armatis, K. Szepeshazi, G. Halmos, M. Kovacs, M. Zarandi, K. Groot, M. Miyazaki, A. Jungwirth, and J. Horvath Proc. Natl. Acad. Sci. U.S.A. 93 1996 7269
113. A.V. Schally, A.M. Comaru-Schally, A. Nagy, M. Kovacs, K. Szepeshazi, A. Plonowski, J.L. Varga, and G. Halmos Front. Neuroendocrinol. 22 2001 248
114. F. Cuttitta, D.N. Carney, J. Mulshine, T.W. Moody, J. Fedorko, A. Fischler, and J.D. Minna Nature 316 1985 823
115. Spindel, E. R.; Giladi, E.; Segerson, T. P.; Nagalla, S. In Recent Progress in Hormone Research, 1993; Vol. 48, pp 365-391
116. Q.M.J. Wang, J.A. Knezetic, A.V. Schally, P.M. Pour, and T.E. Adrian Int. J. Cancer 68 1996 528
117. Y.F. Qin, T. Ertl, R.Z. Cai, G. Halmos, and A.V. Schally Cancer Res. 54 1994 1035
118. Y.F. Qin, T. Ertl, R.Z. Cai, J.E. Horvath, K. Groot, and A.V. Schally Int. J. Cancer 63 1995 257
119. J. Pinski, A.V. Schally, G. Halmos, K. Szepeshazi, K. Groot, K. Obyrne, and R.Z. Cai Br. J. Cancer 70 1994 886
120. Y.F. Qin, G. Halmos, R.Z. Cai, B. Szoke, T. Ertl, and A.V. Schally J. Cancer Res. Clin. Oncol. 120 1994 519
121. J. Pinski, G. Halmos, T. Yano, K. Szepeshazi, Y.F. Qin, T. Ertl, and A.V. Schally Int. J. Cancer 57 1994 574
122. M. Miyazaki, N. Lamharzi, A.V. Schally, G. Halmos, K. Szepeshazi, K. Groot, and R.Z. Cai Eur. J. Cancer 34 1998 710
123. A. Jungwirth, J. Pinski, G. Galvan, G. Halmos, K. Szepeshazi, R.Z. Cai, K. Groot, M. VadilloBuenfil, and A.V. Schally Eur. J. Cancer 33 1997 1141
124. A.V. Schally, K. Szepeshazi, A. Nagy, A.M. Comaru-Schally, and G. Halmos Cell. Mol. Life Sci. 61 2004 1042
125. A. Nagy, P. Armatis, R.Z. Cai, K. Szepeshazi, G. Halmos, and A.V. Schally Proc. Natl. Acad. Sci. U.S.A. 94 1997 652
126. A. Safavy, K.P. Raisch, M.B. Khazaeli, D.J. Buchsbaum, and J.A. Bonner J. Med. Chem. 42 1999 4919