-
1
-
-
0025025442
-
The cysteine switch: A principle of regulation of metalloproteinase activity with potential applicability to the entire matrix metalloproteinase gene family
-
van Wart, H. E.; Birkedal-Hansen, H., The cysteine switch: a principle of regulation of metalloproteinase activity with potential applicability to the entire matrix metalloproteinase gene family. Proc. Natl. Acad. Sci. USA, 1990, 87 (14), 5578-5582.
-
(1990)
Proc. Natl. Acad. Sci. USA
, vol.87
, Issue.14
, pp. 5578-5582
-
-
van Wart, H.E.1
Birkedal-Hansen, H.2
-
2
-
-
0033618337
-
Matrix metalloproteinases
-
Nagase, H.; Woessner, J. F., Jr., Matrix metalloproteinases. J. Biol. Chem., 1999, 274 (31), 21491-21494.
-
(1999)
J. Biol. Chem
, vol.274
, Issue.31
, pp. 21491-21494
-
-
Nagase, H.1
Woessner Jr., J.F.2
-
3
-
-
0037155057
-
Matrix metalloproteinases in vascular remodeling and atherogenesis: The good, the bad, and the ugly
-
Galis, Z. S.; Khatri, J. J., Matrix metalloproteinases in vascular remodeling and atherogenesis: the good, the bad, and the ugly. Circ. Res., 2002, 90 (3), 251-262.
-
(2002)
Circ. Res
, vol.90
, Issue.3
, pp. 251-262
-
-
Galis, Z.S.1
Khatri, J.J.2
-
4
-
-
0030136756
-
Dynamics of matrix turnover during pathologic remodeling of the extracellular matrix
-
Stetler-Stevenson, W. G., Dynamics of matrix turnover during pathologic remodeling of the extracellular matrix. Am. J. Pathol., 1996, 148 (5), 1345-1350.
-
(1996)
Am. J. Pathol
, vol.148
, Issue.5
, pp. 1345-1350
-
-
Stetler-Stevenson, W.G.1
-
5
-
-
0027384917
-
Levels of matrix metalloproteases in bladder cancer correlate with tumor grade and invasion
-
Davies, B.; Waxman, J.; Wasan, H.; Abel, P.; Williams, G.; Krausz, T.; Neal, D.; Thomas, D.; Hanby, A.; Balkwill, F., Levels of matrix metalloproteases in bladder cancer correlate with tumor grade and invasion. Cancer Res., 1993, 53 (22), 5365-5369.
-
(1993)
Cancer Res
, vol.53
, Issue.22
, pp. 5365-5369
-
-
Davies, B.1
Waxman, J.2
Wasan, H.3
Abel, P.4
Williams, G.5
Krausz, T.6
Neal, D.7
Thomas, D.8
Hanby, A.9
Balkwill, F.10
-
6
-
-
78650216761
-
Matrix metalloproteinase-9 and cell division in neuroblastoma cells and bone marrow macrophages
-
Sans-Fons, M. G.; Sole, S.; Sanfeliu, C.; Planas, A. M., Matrix metalloproteinase-9 and cell division in neuroblastoma cells and bone marrow macrophages. Am. J. Pathol., 2010, 177 (6), 2870-2885.
-
(2010)
Am. J. Pathol
, vol.177
, Issue.6
, pp. 2870-2885
-
-
Sans-Fons, M.G.1
Sole, S.2
Sanfeliu, C.3
Planas, A.M.4
-
7
-
-
77956294299
-
Matrix metalloproteinase- 9 is upregulated in nucleophosmin-anaplastic lymphoma kinase-positive anaplastic lymphomas and activated at the cell surface by the chaperone heat shock protein 90 to promote cell invasion
-
Lagarrigue, F.; Dupuis-Coronas, S.; Ramel, D.; Delsol, G.; Tronchere, H.; Payrastre, B.; Gaits-Iacovoni, F., Matrix metalloproteinase- 9 is upregulated in nucleophosmin-anaplastic lymphoma kinase-positive anaplastic lymphomas and activated at the cell surface by the chaperone heat shock protein 90 to promote cell invasion. Cancer Res., 2010, 70 (17), 6978-6987.
-
(2010)
Cancer Res
, vol.70
, Issue.17
, pp. 6978-6987
-
-
Lagarrigue, F.1
Dupuis-Coronas, S.2
Ramel, D.3
Delsol, G.4
Tronchere, H.5
Payrastre, B.6
Gaits-Iacovoni, F.7
-
8
-
-
38549125513
-
The tumor microenvironment: Regulation by MMP-independent effects of tissue inhibitor of metalloproteinases- 2
-
Stetler-Stevenson, W. G., The tumor microenvironment: regulation by MMP-independent effects of tissue inhibitor of metalloproteinases- 2. Cancer Metastasis Rev 2008, 27 (1), 57-66.
-
(2008)
Cancer Metastasis Rev
, vol.27
, Issue.1
, pp. 57-66
-
-
Stetler-Stevenson, W.G.1
-
9
-
-
0028104790
-
Effect of tissue inhibitor of the matrix metalloproteinases-2 expression on the growth and spontaneous metastasis of a human melanoma cell line
-
Montgomery, A. M.; Mueller, B. M.; Reisfeld, R. A.; Taylor, S. M.; DeClerck, Y. A., Effect of tissue inhibitor of the matrix metalloproteinases-2 expression on the growth and spontaneous metastasis of a human melanoma cell line. Cancer Res., 1994, 54 (20), 5467-5473.
-
(1994)
Cancer Res
, vol.54
, Issue.20
, pp. 5467-5473
-
-
Montgomery, A.M.1
Mueller, B.M.2
Reisfeld, R.A.3
Taylor, S.M.4
Declerck, Y.A.5
-
10
-
-
0031042270
-
IgG subclasses in patients with membranoproliferative glomerulonephritis, membranous nephropathy, and lupus nephritis
-
Imai, H.; Hamai, K.; Komatsuda, A.; Ohtani, H.; Miura, A. B.; IgG subclasses in patients with membranoproliferative glomerulonephritis, membranous nephropathy, and lupus nephritis. Kidney Int 1997, 51 (1), 270-276.
-
(1997)
Kidney Int
, vol.51
, Issue.1
, pp. 270-276
-
-
Imai, H.1
Hamai, K.2
Komatsuda, A.3
Ohtani, H.4
Miura, A.B.5
-
11
-
-
0034650486
-
Cell surface-localized matrix metalloproteinase- 9 proteolytically activates TGF-beta and promotes tumor invasion and angiogenesis
-
Yu, Q.; Stamenkovic, I., Cell surface-localized matrix metalloproteinase- 9 proteolytically activates TGF-beta and promotes tumor invasion and angiogenesis. Genes Dev., 2000, 14 (2), 163-176.
-
(2000)
Genes Dev
, vol.14
, Issue.2
, pp. 163-176
-
-
Yu, Q.1
Stamenkovic, I.2
-
12
-
-
0032031861
-
Reduced angiogenesis and tumor progression in gelatinase A-deficient mice
-
Itoh, T.; Tanioka, M.; Yoshida, H.; Yoshioka, T.; Nishimoto, H.; Itohara, S., Reduced angiogenesis and tumor progression in gelatinase A-deficient mice. Cancer Res., 1998, 58 (5), 1048-1051
-
(1998)
Cancer Res
, vol.58
, Issue.5
, pp. 1048-1051
-
-
Itoh, T.1
Tanioka, M.2
Yoshida, H.3
Yoshioka, T.4
Nishimoto, H.5
Itohara, S.6
-
13
-
-
0035989680
-
HSP90 as a new therapeutic target for cancer therapy: The story unfolds
-
Maloney, A.; Workman, P., HSP90 as a new therapeutic target for cancer therapy: the story unfolds. Expert Opin. Biol. Ther., 2002, 2 (1), 3-24.
-
(2002)
Expert Opin. Biol. Ther
, vol.2
, Issue.1
, pp. 3-24
-
-
Maloney, A.1
Workman, P.2
-
14
-
-
0034892432
-
Hsp90: Chaperoning signal transduction
-
Richter, K.; Buchner, J., Hsp90: chaperoning signal transduction. J. Cell Physiol., 2001, 188 (3), 281-290.
-
(2001)
J. Cell Physiol
, vol.188
, Issue.3
, pp. 281-290
-
-
Richter, K.1
Buchner, J.2
-
15
-
-
0034614637
-
The hallmarks of cancer
-
Hanahan, D.; Weinberg, R. A., The hallmarks of cancer. Cell, 2000, 100 (1), 57-70.
-
(2000)
Cell
, vol.100
, Issue.1
, pp. 57-70
-
-
Hanahan, D.1
Weinberg, R.A.2
-
16
-
-
11344280957
-
Extracellular roles for the molecular chaperone, hsp90
-
Eustace, B. K.; Jay, D. G., Extracellular roles for the molecular chaperone, hsp90. Cell Cycle, 2004, 3 (9), 1098-1100.
-
(2004)
Cell Cycle
, vol.3
, Issue.9
, pp. 1098-1100
-
-
Eustace, B.K.1
Jay, D.G.2
-
17
-
-
77955372512
-
Monoclonal antibody 4C5 prevents activation of MMP2 and MMP9 by disrupting their interaction with extracellular HSP90 and inhibits formation of metastatic breast cancer cell deposits
-
Stellas, D.; El Hamidieh, A.; Patsavoudi, E., Monoclonal antibody 4C5 prevents activation of MMP2 and MMP9 by disrupting their interaction with extracellular HSP90 and inhibits formation of metastatic breast cancer cell deposits. BMC Cell Biol., 2010, 11, 51.
-
(2010)
BMC Cell Biol
, vol.11
, pp. 51
-
-
Stellas, D.1
El-Hamidieh, A.2
Patsavoudi, E.3
-
18
-
-
79954994442
-
Extracellular heat shock protein (Hsp)70 and Hsp90alpha assist in matrix metalloproteinase- 2 activation and breast cancer cell migration and invasion
-
Sims, J. D.; McCready, J.; Jay, D. G., Extracellular heat shock protein (Hsp)70 and Hsp90alpha assist in matrix metalloproteinase- 2 activation and breast cancer cell migration and invasion. PLoS, One 2011, 6 (4), e18848.
-
(2011)
PLoS, One
, vol.6
, Issue.4
-
-
Sims, J.D.1
McCready, J.2
Jay, D.G.3
-
19
-
-
0025718981
-
The basigin group of the immunoglobulin superfamily: Complete conservation of a segment in and around transmembrane domains of human and mouse basigin and chicken HT7 antigen
-
Miyauchi, T.; Masuzawa, Y.; Muramatsu, T., The basigin group of the immunoglobulin superfamily: complete conservation of a segment in and around transmembrane domains of human and mouse basigin and chicken HT7 antigen. J. Biochem., 1991, 110 (5), 770-774.
-
(1991)
J. Biochem
, vol.110
, Issue.5
, pp. 770-774
-
-
Miyauchi, T.1
Masuzawa, Y.2
Muramatsu, T.3
-
20
-
-
0025904807
-
Basigin, a new member of the immunoglobulin superfamily: Genes in different mammalian species, glycosylation changes in the molecule from adult organs and possible variation in the Nterminal sequences
-
Kanekura, T.; Miyauchi, T.; Tashiro, M.; Muramatsu, T., Basigin, a new member of the immunoglobulin superfamily: genes in different mammalian species, glycosylation changes in the molecule from adult organs and possible variation in the Nterminal sequences. Cell Struct. Funct., 1991, 16 (1), 23-30.
-
(1991)
Cell Struct. Funct
, vol.16
, Issue.1
, pp. 23-30
-
-
Kanekura, T.1
Miyauchi, T.2
Tashiro, M.3
Muramatsu, T.4
-
21
-
-
0344321892
-
EMMPRIN (extracellular matrix metalloproteinase inducer) is a novel marker of poor outcome in serous ovarian carcinoma
-
Davidson, B.; Goldberg, I.; Berner, A.; Kristensen, G. B.; Reich, R., EMMPRIN (extracellular matrix metalloproteinase inducer) is a novel marker of poor outcome in serous ovarian carcinoma. Clin. Exp. Metastasis, 2003, 20 (2), 161-169.
-
(2003)
Clin. Exp. Metastasis
, vol.20
, Issue.2
, pp. 161-169
-
-
Davidson, B.1
Goldberg, I.2
Berner, A.3
Kristensen, G.B.4
Reich, R.5
-
22
-
-
84860389234
-
Activation of EGFR promotes squamous carcinoma SCC10A cell migration and invasion via inducing EMT-like phenotype change and MMP-9-mediated degradation of E-cadherin
-
Zuo, J. H.; Zhu, W.; Li, M. Y.; Li, X. H.; Yi, H.; Zeng, G. Q.; Wan, X. X.; He, Q. Y.; Li, J. H.; Qu, J. Q.; Chen, Y.; Xiao, Z. Q., Activation of EGFR promotes squamous carcinoma SCC10A cell migration and invasion via inducing EMT-like phenotype change and MMP-9-mediated degradation of E-cadherin. J. Cell Biochem., 2011, 112 (9), 2508-2517.
-
(2011)
J. Cell Biochem
, vol.112
, Issue.9
, pp. 2508-2517
-
-
Zuo, J.H.1
Zhu, W.2
Li, M.Y.3
Li, X.H.4
Yi, H.5
Zeng, G.Q.6
Wan, X.X.7
He, Q.Y.8
Li, J.H.9
Qu, J.Q.10
Chen, Y.11
Xiao, Z.Q.12
-
23
-
-
0033388462
-
MMP inhibitors: Experimental and clinical studies
-
Belotti, D.; Paganoni, P.; Giavazzi, R., MMP inhibitors: experimental and clinical studies. Int. J. Biol. Markers, 1999, 14 (4), 232-238.
-
(1999)
Int. J. Biol. Markers
, vol.14
, Issue.4
, pp. 232-238
-
-
Belotti, D.1
Paganoni, P.2
Giavazzi, R.3
-
24
-
-
0028598887
-
Protease inhibitors: Role and potential therapeutic use in human cancer
-
DeClerck, Y. A.; Imren, S., Protease inhibitors: role and potential therapeutic use in human cancer. Eur. J. Cancer, 1994, 30A (14), 2170-2180.
-
(1994)
Eur. J. Cancer
, vol.30 A
, Issue.14
, pp. 2170-2180
-
-
Declerck, Y.A.1
Imren, S.2
-
25
-
-
79960694567
-
Orally active, antimetastatic, nontoxic diphenyl ether-derived carbamoylphosphonate matrix metalloproteinase inhibitors
-
Frant, J.; Veerendhar, A.; Chernilovsky, T.; Nedvetzki, S.; Vaksman, O.; Hoffman, A.; Breuer, E.; Reich, R., Orally active, antimetastatic, nontoxic diphenyl ether-derived carbamoylphosphonate matrix metalloproteinase inhibitors. Chem. Med. Chem., 2011, 6 (8), 1471-1477.
-
(2011)
Chem. Med. Chem
, vol.6
, Issue.8
, pp. 1471-1477
-
-
Frant, J.1
Veerendhar, A.2
Chernilovsky, T.3
Nedvetzki, S.4
Vaksman, O.5
Hoffman, A.6
Breuer, E.7
Reich, R.8
-
26
-
-
0033999308
-
Matrix metalloproteinases: Biologic activity and clinical implications
-
Nelson, A. R.; Fingleton, B.; Rothenberg, M. L.; Matrisian, L. M., Matrix metalloproteinases: biologic activity and clinical implications. J. Clin. Oncol., 2000, 18 (5), 1135-1149.
-
(2000)
J. Clin. Oncol
, vol.18
, Issue.5
, pp. 1135-1149
-
-
Nelson, A.R.1
Fingleton, B.2
Rothenberg, M.L.3
Matrisian, L.M.4
-
27
-
-
79960414991
-
Smallmolecule anticancer compounds selectively target the hemopexin domain of matrix metalloproteinase-9
-
Dufour, A.; Sampson, N. S.; Li, J.; Kuscu, C.; Rizzo, R. C.; Deleon, J. L.; Zhi, J.; Jaber, N.; Liu, E.; Zucker, S.; Cao, J., Smallmolecule anticancer compounds selectively target the hemopexin domain of matrix metalloproteinase-9. Cancer Res., 2011, 71 (14), 4977-4988.
-
(2011)
Cancer Res
, vol.71
, Issue.14
, pp. 4977-4988
-
-
Dufour, A.1
Sampson, N.S.2
Li, J.3
Kuscu, C.4
Rizzo, R.C.5
Deleon, J.L.6
Zhi, J.7
Jaber, N.8
Liu, E.9
Zucker, S.10
Cao, J.11
-
28
-
-
0030609810
-
1.8-A crystal structure of the catalytic domain of human neutrophil collagenase (matrix metalloproteinase-8) complexed with a peptidomimetic hydroxamate primed-side inhibitor with a distinct selectivity profile
-
Betz, M.; Huxley, P.; Davies, S. J.; Mushtaq, Y.; Pieper, M.; Tschesche, H.; Bode, W.; Gomis-Ruth, F. X., 1.8-A crystal structure of the catalytic domain of human neutrophil collagenase (matrix metalloproteinase-8) complexed with a peptidomimetic hydroxamate primed-side inhibitor with a distinct selectivity profile. Eur. J. Biochem., 1997, 247 (1), 356-363.
-
(1997)
Eur. J. Biochem
, vol.247
, Issue.1
, pp. 356-363
-
-
Betz, M.1
Huxley, P.2
Davies, S.J.3
Mushtaq, Y.4
Pieper, M.5
Tschesche, H.6
Bode, W.7
Gomis-Ruth, F.X.8
-
29
-
-
0033034041
-
Clinical studies with matrix metalloproteinase inhibitors
-
Brown, P. D., Clinical studies with matrix metalloproteinase inhibitors. Apmis, 1999, 107 (1), 174-180.
-
(1999)
Apmis
, vol.107
, Issue.1
, pp. 174-180
-
-
Brown, P.D.1
-
30
-
-
0027251836
-
A synthetic matrix metalloproteinase inhibitor decreases tumor burden and prolongs survival of mice bearing human ovarian carcinoma xenografts
-
Davies, B.; Brown, P. D.; East, N.; Crimmin, M. J.; Balkwill, F. R., A synthetic matrix metalloproteinase inhibitor decreases tumor burden and prolongs survival of mice bearing human ovarian carcinoma xenografts. Cancer Res., 1993, 53 (9), 2087-2091.
-
(1993)
Cancer Res
, vol.53
, Issue.9
, pp. 2087-2091
-
-
Davies, B.1
Brown, P.D.2
East, N.3
Crimmin, M.J.4
Balkwill, F.R.5
-
31
-
-
0032782424
-
The matrix metalloproteinase inhibitor batimastat inhibits angiogenesis in liver metastases of B16F1 melanoma cells
-
Wylie, S.; MacDonald, I. C.; Varghese, H. J.; Schmidt, E. E.; Morris, V. L.; Groom, A. C.; Chambers, A. F., The matrix metalloproteinase inhibitor batimastat inhibits angiogenesis in liver metastases of B16F1 melanoma cells. Clin. Exp. Metastasis, 1999, 17 (2), 111-117.
-
(1999)
Clin. Exp. Metastasis
, vol.17
, Issue.2
, pp. 111-117
-
-
Wylie, S.1
Macdonald, I.C.2
Varghese, H.J.3
Schmidt, E.E.4
Morris, V.L.5
Groom, A.C.6
Chambers, A.F.7
-
32
-
-
0029888124
-
The matrix metalloproteinase inhibitor batimastat (BB-94) retards human breast cancer solid tumor growth but not ascites formation in nude mice
-
Low, J. A.; Johnson, M. D.; Bone, E. A.; Dickson, R. B., The matrix metalloproteinase inhibitor batimastat (BB-94) retards human breast cancer solid tumor growth but not ascites formation in nude mice. Clin. Cancer Res., 1996, 2 (7), 1207-1214.
-
(1996)
Clin. Cancer Res
, vol.2
, Issue.7
, pp. 1207-1214
-
-
Low, J.A.1
Johnson, M.D.2
Bone, E.A.3
Dickson, R.B.4
-
33
-
-
0031669587
-
Effects of matrix metalloproteinase inhibitor BB-94 on liver cancer growth and metastasis in a patient-like orthotopic model LCI-D20
-
Bu, W.; Tang, Z. Y.; Sun, F. X.; Ye, S. L.; Liu, K. D.; Xue, Q.; Chen, J.; Gao, D. M., Effects of matrix metalloproteinase inhibitor BB-94 on liver cancer growth and metastasis in a patient-like orthotopic model LCI-D20. Hepatogastroenterology, 1998, 45 (22), 1056-1061.
-
(1998)
Hepatogastroenterology
, vol.45
, Issue.22
, pp. 1056-1061
-
-
Bu, W.1
Tang, Z.Y.2
Sun, F.X.3
Ye, S.L.4
Liu, K.D.5
Xue, Q.6
Chen, J.7
Gao, D.M.8
-
34
-
-
0029165411
-
Inhibition of organ invasion by the matrix metalloproteinase inhibitor batimastat (BB-94) in two human colon carcinoma metastasis models
-
Watson, S. A.; Morris, T. M.; Robinson, G.; Crimmin, M. J.; Brown, P. D.; Hardcastle, J. D., Inhibition of organ invasion by the matrix metalloproteinase inhibitor batimastat (BB-94) in two human colon carcinoma metastasis models. Cancer Res., 1995, 55 (16), 3629-3633.
-
(1995)
Cancer Res
, vol.55
, Issue.16
, pp. 3629-3633
-
-
Watson, S.A.1
Morris, T.M.2
Robinson, G.3
Crimmin, M.J.4
Brown, P.D.5
Hardcastle, J.D.6
-
35
-
-
0028129059
-
Inhibition of the metastatic spread and growth of B16-BL6 murine melanoma by a synthetic matrix metalloproteinase inhibitor
-
Chirivi, R. G.; Garofalo, A.; Crimmin, M. J.; Bawden, L. J.; Stoppacciaro, A.; Brown, P. D.; Giavazzi, R., Inhibition of the metastatic spread and growth of B16-BL6 murine melanoma by a synthetic matrix metalloproteinase inhibitor. Int. J. Cancer, 1994, 58 (3), 460-464.
-
(1994)
Int. J. Cancer
, vol.58
, Issue.3
, pp. 460-464
-
-
Chirivi, R.G.1
Garofalo, A.2
Crimmin, M.J.3
Bawden, L.J.4
Stoppacciaro, A.5
Brown, P.D.6
Giavazzi, R.7
-
36
-
-
0028939303
-
Inhibition of angiogenesis and murine hemangioma growth by batimastat, a synthetic inhibitor of matrix metalloproteinases
-
Taraboletti, G.; Garofalo, A.; Belotti, D.; Drudis, T.; Borsotti, P.; Scanziani, E.; Brown, P. D.; Giavazzi, R., Inhibition of angiogenesis and murine hemangioma growth by batimastat, a synthetic inhibitor of matrix metalloproteinases. J. Natl. Cancer Inst., 1995, 87 (4), 293-298.
-
(1995)
J. Natl. Cancer Inst
, vol.87
, Issue.4
, pp. 293-298
-
-
Taraboletti, G.1
Garofalo, A.2
Belotti, D.3
Drudis, T.4
Borsotti, P.5
Scanziani, E.6
Brown, P.D.7
Giavazzi, R.8
-
37
-
-
0031148314
-
Matrix metalloproteinase inhibition attenuates human pancreatic cancer growth in vitro and decreases mortality and tumorigenesis in vivo
-
Zervos, E. E.; Norman, J. G.; Gower, W. R.; Franz, M. G.; Rosemurgy, A. S., Matrix metalloproteinase inhibition attenuates human pancreatic cancer growth in vitro and decreases mortality and tumorigenesis in vivo. J. Surg. Res., 1997, 69 (2), 367-371.
-
(1997)
J. Surg. Res
, vol.69
, Issue.2
, pp. 367-371
-
-
Zervos, E.E.1
Norman, J.G.2
Gower, W.R.3
Franz, M.G.4
Rosemurgy, A.S.5
-
38
-
-
0032952694
-
Inhibition of gelatinase A (MMP-2) by batimastat and captopril reduces tumor growth and lung metastases in mice bearing Lewis lung carcinoma
-
Prontera, C.; Mariani, B.; Rossi, C.; Poggi, A.; Rotilio, D., Inhibition of gelatinase A (MMP-2) by batimastat and captopril reduces tumor growth and lung metastases in mice bearing Lewis lung carcinoma. Int. J. Cancer, 1999, 81 (5), 761-766.
-
(1999)
Int. J. Cancer
, vol.81
, Issue.5
, pp. 761-766
-
-
Prontera, C.1
Mariani, B.2
Rossi, C.3
Poggi, A.4
Rotilio, D.5
-
39
-
-
0029847630
-
Phase I trial of a novel matrix metalloproteinase inhibitor batimastat (BB-94) in patients with advanced cancer. Invest
-
Wojtowicz-Praga, S.; Low, J.; Marshall, J.; Ness, E.; Dickson, R.; Barter, J.; Sale, M.; McCann, P.; Moore, J.; Cole, A.; Hawkins, M. J., Phase I trial of a novel matrix metalloproteinase inhibitor batimastat (BB-94) in patients with advanced cancer. Invest. New Drugs, 1996, 14 (2), 193-202.
-
(1996)
New Drugs
, vol.14
, Issue.2
, pp. 193-202
-
-
Wojtowicz-Praga, S.1
Low, J.2
Marshall, J.3
Ness, E.4
Dickson, R.5
Barter, J.6
Sale, M.7
McCann, P.8
Moore, J.9
Cole, A.10
Hawkins, M.J.11
-
40
-
-
0033032228
-
Phase I study of intrapleural batimastat (BB-94), a matrix metalloproteinase inhibitor, in the treatment of malignant pleural effusions. Clin
-
Macaulay, V. M.; O'Byrne, K. J.; Saunders, M. P.; Braybrooke, J. P.; Long, L.; Gleeson, F.; Mason, C. S.; Harris, A. L.; Brown, P.; Talbot, D. C., Phase I study of intrapleural batimastat (BB-94), a matrix metalloproteinase inhibitor, in the treatment of malignant pleural effusions. Clin. Cancer Res., 1999, 5 (3), 513-520.
-
(1999)
Cancer Res
, vol.5
, Issue.3
, pp. 513-520
-
-
Macaulay, V.M.1
O'Byrne, K.J.2
Saunders, M.P.3
Braybrooke, J.P.4
Long, L.5
Gleeson, F.6
Mason, C.S.7
Harris, A.L.8
Brown, P.9
Talbot, D.C.10
-
41
-
-
0030929371
-
Matrix metalloproteinase inhibitors
-
Wojtowicz-Praga, S. M.; Dickson, R. B.; Hawkins, M. J., Matrix metalloproteinase inhibitors. Invest New Drugs 1997, 15 (1), 61-75.
-
(1997)
Invest New Drugs
, vol.15
, Issue.1
, pp. 61-75
-
-
Wojtowicz-Praga, S.M.1
Dickson, R.B.2
Hawkins, M.J.3
-
42
-
-
0031776982
-
Phase I trial of Marimastat, a novel matrix metalloproteinase inhibitor, administered orally to patients with advanced lung cancer
-
Wojtowicz-Praga, S.; Torri, J.; Johnson, M.; Steen, V.; Marshall, J.; Ness, E.; Dickson, R.; Sale, M.; Rasmussen, H. S.; Chiodo, T. A.; Hawkins, M. J., Phase I trial of Marimastat, a novel matrix metalloproteinase inhibitor, administered orally to patients with advanced lung cancer. J. Clin. Oncol., 1998, 16 (6), 2150-2156.
-
(1998)
J. Clin. Oncol
, vol.16
, Issue.6
, pp. 2150-2156
-
-
Wojtowicz-Praga, S.1
Torri, J.2
Johnson, M.3
Steen, V.4
Marshall, J.5
Ness, E.6
Dickson, R.7
Sale, M.8
Rasmussen, H.S.9
Chiodo, T.A.10
Hawkins, M.J.11
-
43
-
-
0031882946
-
Results of single and repeat dose studies of the oral matrix metalloproteinase inhibitor marimastat in healthy male volunteers
-
Millar, A. W.; Brown, P. D.; Moore, J.; Galloway, W. A.; Cornish, A. G.; Lenehan, T. J.; Lynch, K. P., Results of single and repeat dose studies of the oral matrix metalloproteinase inhibitor marimastat in healthy male volunteers. Br. J. Clin. Pharmacol., 1998, 45 (1), 21-26.
-
(1998)
Br. J. Clin. Pharmacol
, vol.45
, Issue.1
, pp. 21-26
-
-
Millar, A.W.1
Brown, P.D.2
Moore, J.3
Galloway, W.A.4
Cornish, A.G.5
Lenehan, T.J.6
Lynch, K.P.7
-
44
-
-
0033509553
-
Marimastat in patients with advanced pancreatic cancer: A dose-finding study
-
Rosemurgy, A.; Harris, J.; Langleben, A.; Casper, E.; Goode, S.; Rasmussen, H., Marimastat in patients with advanced pancreatic cancer: a dose-finding study. Am J Clin Oncol 1999, 22 (3), 247-252.
-
(1999)
Am J Clin Oncol
, vol.22
, Issue.3
, pp. 247-252
-
-
Rosemurgy, A.1
Harris, J.2
Langleben, A.3
Casper, E.4
Goode, S.5
Rasmussen, H.6
-
45
-
-
18244399611
-
Phase I trial of the matrix metalloproteinase inhibitor marimastat combined with carboplatin and paclitaxel in patients with advanced non-small cell lung cancer
-
Goffin, J. R.; Anderson, I. C.; Supko, J. G.; Eder, J. P., Jr.; Shapiro, G. I.; Lynch, T. J.; Shipp, M.; Johnson, B. E.; Skarin, A. T., Phase I trial of the matrix metalloproteinase inhibitor marimastat combined with carboplatin and paclitaxel in patients with advanced non-small cell lung cancer. Clin. Cancer Res., 2005, 11 (9), 3417-3424.
-
(2005)
Clin. Cancer Res
, vol.11
, Issue.9
, pp. 3417-3424
-
-
Goffin, J.R.1
Anderson, I.C.2
Supko, J.G.3
Eder Jr., J.P.4
Shapiro, G.I.5
Lynch, T.J.6
Shipp, M.7
Johnson, B.E.8
Skarin, A.T.9
-
46
-
-
3042802135
-
Marimastat as maintenance therapy for patients with advanced gastric cancer: A randomised trial
-
Bramhall, S. R.; Hallissey, M. T.; Whiting, J.; Scholefield, J.; Tierney, G.; Stuart, R. C.; Hawkins, R. E.; McCulloch, P.; Maughan, T.; Brown, P. D.; Baillet, M.; Fielding, J. W., Marimastat as maintenance therapy for patients with advanced gastric cancer: a randomised trial. Br. J. Cancer, 2002, 86 (12), 1864-1870.
-
(2002)
Br. J. Cancer
, vol.86
, Issue.12
, pp. 1864-1870
-
-
Bramhall, S.R.1
Hallissey, M.T.2
Whiting, J.3
Scholefield, J.4
Tierney, G.5
Stuart, R.C.6
Hawkins, R.E.7
McCulloch, P.8
Maughan, T.9
Brown, P.D.10
Baillet, M.11
Fielding, J.W.12
-
47
-
-
0036499078
-
Phase II trial of temozolomide plus the matrix metalloproteinase inhibitor, marimastat, in recurrent and progressive glioblastoma multiforme
-
Groves, M. D.; Puduvalli, V. K.; Hess, K. R.; Jaeckle, K. A.; Peterson, P.; Yung, W. K.; Levin, V. A., Phase II trial of temozolomide plus the matrix metalloproteinase inhibitor, marimastat, in recurrent and progressive glioblastoma multiforme. J. Clin. Oncol., 2002, 20 (5), 1383-1388.
-
(2002)
J. Clin. Oncol
, vol.20
, Issue.5
, pp. 1383-1388
-
-
Groves, M.D.1
Puduvalli, V.K.2
Hess, K.R.3
Jaeckle, K.A.4
Peterson, P.5
Yung, W.K.6
Levin, V.A.7
-
48
-
-
33745793404
-
Randomized, double-blind, placebo-controlled trial of marimastat in glioblastoma multiforme patients following surgery and irradiation
-
Levin, V. A.; Phuphanich, S.; Yung, W. K.; Forsyth, P. A.; Maestro, R. D.; Perry, J. R.; Fuller, G. N.; Baillet, M., Randomized, double-blind, placebo-controlled trial of marimastat in glioblastoma multiforme patients following surgery and irradiation. J. Neurooncol., 2006, 78 (3), 295-302.
-
(2006)
J. Neurooncol
, vol.78
, Issue.3
, pp. 295-302
-
-
Levin, V.A.1
Phuphanich, S.2
Yung, W.K.3
Forsyth, P.A.4
Maestro, R.D.5
Perry, J.R.6
Fuller, G.N.7
Baillet, M.8
-
49
-
-
0037207968
-
Randomised double blind placebo control study of adjuvant treatment with the metalloproteinase inhibitor, Marimastat in patients with inoperable colorectal hepatic metastases: Significant survival advantage in patients with musculoskeletal side-effects
-
King, J.; Zhao, J.; Clingan, P.; Morris, D., Randomised double blind placebo control study of adjuvant treatment with the metalloproteinase inhibitor, Marimastat in patients with inoperable colorectal hepatic metastases: significant survival advantage in patients with musculoskeletal side-effects. Anticancer Res., 2003, 23 (1B), 639-645.
-
(2003)
Anticancer Res
, vol.23
, Issue.1 B
, pp. 639-645
-
-
King, J.1
Zhao, J.2
Clingan, P.3
Morris, D.4
-
50
-
-
34250630512
-
A phase II and pharmacological study of the matrix metalloproteinase inhibitor (MMPI) COL-3 in patients with advanced soft tissue sarcomas
-
Chu, Q. S.; Forouzesh, B.; Syed, S.; Mita, M.; Schwartz, G.; Cooper, J.; Curtright, J.; Rowinsky, E. K., A phase II and pharmacological study of the matrix metalloproteinase inhibitor (MMPI) COL-3 in patients with advanced soft tissue sarcomas. Invest. New Drugs, 2007, 25 (4), 359-367.
-
(2007)
Invest. New Drugs
, vol.25
, Issue.4
, pp. 359-367
-
-
Chu, Q.S.1
Forouzesh, B.2
Syed, S.3
Mita, M.4
Schwartz, G.5
Cooper, J.6
Curtright, J.7
Rowinsky, E.K.8
-
51
-
-
0032710567
-
BAY 12-9566, a novel inhibitor of matrix metalloproteinases with antiangiogenic activity
-
Gatto, C.; Rieppi, M.; Borsotti, P.; Innocenti, S.; Ceruti, R.; Drudis, T.; Scanziani, E.; Casazza, A. M.; Taraboletti, G.; Giavazzi, R., BAY 12-9566, a novel inhibitor of matrix metalloproteinases with antiangiogenic activity. Clin. Cancer Res., 1999, 5 (11), 3603-3607.
-
(1999)
Clin. Cancer Res
, vol.5
, Issue.11
, pp. 3603-3607
-
-
Gatto, C.1
Rieppi, M.2
Borsotti, P.3
Innocenti, S.4
Ceruti, R.5
Drudis, T.6
Scanziani, E.7
Casazza, A.M.8
Taraboletti, G.9
Giavazzi, R.10
-
52
-
-
33751108283
-
Novel therapies for the treatment of small-cell lung cancer: A time for cautious optimism?
-
Board, R. E.; Thatcher, N.; Lorigan, P., Novel therapies for the treatment of small-cell lung cancer: a time for cautious optimism? Drugs, 2006, 66 (15), 1919-19131.
-
(2006)
Drugs
, vol.66
, Issue.15
, pp. 1919-19131
-
-
Board, R.E.1
Thatcher, N.2
Lorigan, P.3
-
53
-
-
0141688333
-
Comparison of gemcitabine versus the matrix metalloproteinase inhibitor BAY 12-9566 in patients with advanced or metastatic adenocarcinoma of the pancreas: A phase III trial of the National Cancer Institute of Canada Clinical Trials Group
-
Moore, M. J.; Hamm, J.; Dancey, J.; Eisenberg, P. D.; Dagenais, M.; Fields, A.; Hagan, K.; Greenberg, B.; Colwell, B.; Zee, B.; Tu, D.; Ottaway, J.; Humphrey, R.; Seymour, L., Comparison of gemcitabine versus the matrix metalloproteinase inhibitor BAY 12-9566 in patients with advanced or metastatic adenocarcinoma of the pancreas: a phase III trial of the National Cancer Institute of Canada Clinical Trials Group. J. Clin. Oncol., 2003, 21 (17), 3296-3302.
-
(2003)
J. Clin. Oncol
, vol.21
, Issue.17
, pp. 3296-3302
-
-
Moore, M.J.1
Hamm, J.2
Dancey, J.3
Eisenberg, P.D.4
Dagenais, M.5
Fields, A.6
Hagan, K.7
Greenberg, B.8
Colwell, B.9
Zee, B.10
Tu, D.11
Ottaway, J.12
Humphrey, R.13
Seymour, L.14
-
54
-
-
33745963397
-
A phase III randomized trial of BAY 12-9566 (tanomastat) as maintenance therapy in patients with advanced ovarian cancer responsive to primary surgery and paclitaxel/ platinum containing chemotherapy: A National Cancer Institute of Canada Clinical Trials Group Study
-
Hirte, H.; Vergote, I. B.; Jeffrey, J. R.; Grimshaw, R. N.; Coppieters, S.; Schwartz, B.; Tu, D.; Sadura, A.; Brundage, M.; Seymour, L., A phase III randomized trial of BAY 12-9566 (tanomastat) as maintenance therapy in patients with advanced ovarian cancer responsive to primary surgery and paclitaxel/ platinum containing chemotherapy: a National Cancer Institute of Canada Clinical Trials Group Study. Gynecol. Oncol., 2006, 102 (2), 300-308.
-
(2006)
Gynecol. Oncol
, vol.102
, Issue.2
, pp. 300-308
-
-
Hirte, H.1
Vergote, I.B.2
Jeffrey, J.R.3
Grimshaw, R.N.4
Coppieters, S.5
Schwartz, B.6
Tu, D.7
Sadura, A.8
Brundage, M.9
Seymour, L.10
-
55
-
-
0032837028
-
Broad antitumor and antiangiogenic activities of AG3340, a potent and selective MMP inhibitor undergoing advanced oncology clinical trials
-
Shalinsky, D. R.; Brekken, J.; Zou, H.; McDermott, C. D.; Forsyth, P.; Edwards, D.; Margosiak, S.; Bender, S.; Truitt, G.; Wood, A.; Varki, N. M.; Appelt, K., Broad antitumor and antiangiogenic activities of AG3340, a potent and selective MMP inhibitor undergoing advanced oncology clinical trials. Ann N Y Acad Sci 1999, 878, 236-270.
-
(1999)
Ann N Y Acad Sci
, vol.878
, pp. 236-270
-
-
Shalinsky, D.R.1
Brekken, J.2
Zou, H.3
McDermott, C.D.4
Forsyth, P.5
Edwards, D.6
Margosiak, S.7
Bender, S.8
Truitt, G.9
Wood, A.10
Varki, N.M.11
Appelt, K.12
-
56
-
-
0030816454
-
Rodent pharmacokinetic and anti-tumor efficacy studies with a series of synthetic inhibitors of matrix metalloproteinases
-
Santos, O.; McDermott, C. D.; Daniels, R. G.; Appelt, K., Rodent pharmacokinetic and anti-tumor efficacy studies with a series of synthetic inhibitors of matrix metalloproteinases. Clin. Exp. Metastasis, 1997, 15 (5), 499-508.
-
(1997)
Clin. Exp. Metastasis
, vol.15
, Issue.5
, pp. 499-508
-
-
Santos, O.1
McDermott, C.D.2
Daniels, R.G.3
Appelt, K.4
-
57
-
-
0032449008
-
Antitumor efficacy of AG3340 associated with maintenance of minimum effective plasma concentrations and not total daily dose, exposure or peak plasma concentrations
-
Shalinsky, D. R.; Brekken, J.; Zou, H.; Kolis, S.; Wood, A.; Webber, S.; Appelt, K., Antitumor efficacy of AG3340 associated with maintenance of minimum effective plasma concentrations and not total daily dose, exposure or peak plasma concentrations. Invest. New Drugs, 1998, 16 (4), 303-313.
-
(1998)
Invest. New Drugs
, vol.16
, Issue.4
, pp. 303-313
-
-
Shalinsky, D.R.1
Brekken, J.2
Zou, H.3
Kolis, S.4
Wood, A.5
Webber, S.6
Appelt, K.7
-
58
-
-
0032791421
-
Marked antiangiogenic and antitumor efficacy of AG3340 in chemoresistant human nonsmall cell lung cancer tumors: Single agent and combination chemotherapy studies
-
Shalinsky, D. R.; Brekken, J.; Zou, H.; Bloom, L. A.; McDermott, C. D.; Zook, S.; Varki, N. M.; Appelt, K., Marked antiangiogenic and antitumor efficacy of AG3340 in chemoresistant human nonsmall cell lung cancer tumors: single agent and combination chemotherapy studies. Clin. Cancer Res., 1999, 5 (7), 1905-1917.
-
(1999)
Clin. Cancer Res
, vol.5
, Issue.7
, pp. 1905-1917
-
-
Shalinsky, D.R.1
Brekken, J.2
Zou, H.3
Bloom, L.A.4
McDermott, C.D.5
Zook, S.6
Varki, N.M.7
Appelt, K.8
-
59
-
-
0032905581
-
Marked inhibition of tumor growth in a malignant glioma tumor model by a novel synthetic matrix metalloproteinase inhibitor AG3340
-
Price, A.; Shi, Q.; Morris, D.; Wilcox, M. E.; Brasher, P. M.; Rewcastle, N. B.; Shalinsky, D.; Zou, H.; Appelt, K.; Johnston, R. N.; Yong, V. W.; Edwards, D.; Forsyth, P., Marked inhibition of tumor growth in a malignant glioma tumor model by a novel synthetic matrix metalloproteinase inhibitor AG3340. Clin. Cancer Res., 1999, 5 (4), 845-854.
-
(1999)
Clin. Cancer Res
, vol.5
, Issue.4
, pp. 845-854
-
-
Price, A.1
Shi, Q.2
Morris, D.3
Wilcox, M.E.4
Brasher, P.M.5
Rewcastle, N.B.6
Shalinsky, D.7
Zou, H.8
Appelt, K.9
Johnston, R.N.10
Yong, V.W.11
Edwards, D.12
Forsyth, P.13
-
60
-
-
0036118399
-
Matrix metalloproteinases and matrix metalloproteinase inhibitors in lung cancer
-
Bonomi, P., Matrix metalloproteinases and matrix metalloproteinase inhibitors in lung cancer. Semin Oncol., 2002, 29 (1 Suppl 4), 78-86.
-
(2002)
Semin Oncol
, vol.29
, Issue.1 SUPPL. 4
, pp. 78-86
-
-
Bonomi, P.1
-
61
-
-
20044388325
-
Phase III study of matrix metalloproteinase inhibitor prinomastat in non-small-cell lung cancer
-
Bissett, D.; O'Byrne, K. J.; von Pawel, J.; Gatzemeier, U.; Price, A.; Nicolson, M.; Mercier, R.; Mazabel, E.; Penning, C.; Zhang, M. H.; Collier, M. A.; Shepherd, F. A., Phase III study of matrix metalloproteinase inhibitor prinomastat in non-small-cell lung cancer. J. Clin. Oncol., 2005, 23 (4), 842-849.
-
(2005)
J. Clin. Oncol
, vol.23
, Issue.4
, pp. 842-849
-
-
Bissett, D.1
O'Byrne, K.J.2
von Pawel, J.3
Gatzemeier, U.4
Price, A.5
Nicolson, M.6
Mercier, R.7
Mazabel, E.8
Penning, C.9
Zhang, M.H.10
Collier, M.A.11
Shepherd, F.A.12
-
62
-
-
0142029001
-
Venous thromboembolism among patients with advanced lung cancer randomized to prinomastat or placebo, plus chemotherapy
-
Behrendt, C. E.; Ruiz, R. B., Venous thromboembolism among patients with advanced lung cancer randomized to prinomastat or placebo, plus chemotherapy. Thromb. Haemost., 2003, 90 (4), 734-737.
-
(2003)
Thromb. Haemost
, vol.90
, Issue.4
, pp. 734-737
-
-
Behrendt, C.E.1
Ruiz, R.B.2
-
63
-
-
0033025398
-
Promising new developments in cancer chemotherapy
-
Ferrante, K.; Winograd, B.; Canetta, R., Promising new developments in cancer chemotherapy. Cancer Chemother. Pharmacol., 1999, 43 Suppl, S61-S68.
-
(1999)
Cancer Chemother. Pharmacol
, vol.43
, Issue.SUPPL.
-
-
Ferrante, K.1
Winograd, B.2
Canetta, R.3
-
64
-
-
0037314611
-
Reduction of wound angiogenesis in patients treated with BMS-275291, a broad spectrum matrix metalloproteinase inhibitor
-
Lockhart, A. C.; Braun, R. D.; Yu, D.; Ross, J. R.; Dewhirst, M. W.; Humphrey, J. S.; Thompson, S.; Williams, K. M.; Klitzman, B.; Yuan, F.; Grichnik, J. M.; Proia, A. D.; Conway, D. A.; Hurwitz, H. I., Reduction of wound angiogenesis in patients treated with BMS-275291, a broad spectrum matrix metalloproteinase inhibitor. Clin. Cancer Res., 2003, 9 (2), 586-593.
-
(2003)
Clin. Cancer Res
, vol.9
, Issue.2
, pp. 586-593
-
-
Lockhart, A.C.1
Braun, R.D.2
Yu, D.3
Ross, J.R.4
Dewhirst, M.W.5
Humphrey, J.S.6
Thompson, S.7
Williams, K.M.8
Klitzman, B.9
Yuan, F.10
Grichnik, J.M.11
Proia, A.D.12
Conway, D.A.13
Hurwitz, H.I.14
-
65
-
-
12144287866
-
A randomized phase II feasibility trial of BMS-275291 in patients with early stage breast cancer
-
Miller, K. D.; Saphner, T. J.; Waterhouse, D. M.; Chen, T. T.; Rush-Taylor, A.; Sparano, J. A.; Wolff, A. C.; Cobleigh, M. A.; Galbraith, S.; Sledge, G. W., A randomized phase II feasibility trial of BMS-275291 in patients with early stage breast cancer. Clin. Cancer Res., 2004, 10 (6), 1971-1975.
-
(2004)
Clin. Cancer Res
, vol.10
, Issue.6
, pp. 1971-1975
-
-
Miller, K.D.1
Saphner, T.J.2
Waterhouse, D.M.3
Chen, T.T.4
Rush-Taylor, A.5
Sparano, J.A.6
Wolff, A.C.7
Cobleigh, M.A.8
Galbraith, S.9
Sledge, G.W.10
-
66
-
-
0036229815
-
BMS-275291. Bristol-Myers Squibb
-
Poulaki, V., BMS-275291. Bristol-Myers Squibb. Curr. Opin. Investig. Drugs, 2002, 3 (3), 500-504.
-
(2002)
Curr. Opin. Investig. Drugs
, vol.3
, Issue.3
, pp. 500-504
-
-
Poulaki, V.1
-
67
-
-
12144286743
-
A phase I study of oral BMS-275291, a novel nonhydroxamate sheddase-sparing matrix metalloproteinase inhibitor, in patients with advanced or metastatic cancer
-
Rizvi, N. A.; Humphrey, J. S.; Ness, E. A.; Johnson, M. D.; Gupta, E.; Williams, K.; Daly, D. J.; Sonnichsen, D.; Conway, D.; Marshall, J.; Hurwitz, H., A phase I study of oral BMS-275291, a novel nonhydroxamate sheddase-sparing matrix metalloproteinase inhibitor, in patients with advanced or metastatic cancer. Clin. Cancer Res., 2004, 10 (6), 1963-1970.
-
(2004)
Clin. Cancer Res
, vol.10
, Issue.6
, pp. 1963-1970
-
-
Rizvi, N.A.1
Humphrey, J.S.2
Ness, E.A.3
Johnson, M.D.4
Gupta, E.5
Williams, K.6
Daly, D.J.7
Sonnichsen, D.8
Conway, D.9
Marshall, J.10
Hurwitz, H.11
-
68
-
-
8444248227
-
Randomized phase II feasibility study of combining the matrix metalloproteinase inhibitor BMS-275291 with paclitaxel plus carboplatin in advanced non-small cell lung cancer
-
Douillard, J. Y.; Peschel, C.; Shepherd, F.; Paz-Ares, L.; Arnold, A.; Davis, M.; Tonato, M.; Smylie, M.; Tu, D.; Voi, M.; Humphrey, J.; Ottaway, J.; Young, K.; Vreckem, A. V.; Seymour, L., Randomized phase II feasibility study of combining the matrix metalloproteinase inhibitor BMS-275291 with paclitaxel plus carboplatin in advanced non-small cell lung cancer. Lung Cancer 2004, 46 (3), 361-368.
-
(2004)
Lung Cancer
, vol.46
, Issue.3
, pp. 361-368
-
-
Douillard, J.Y.1
Peschel, C.2
Shepherd, F.3
Paz-Ares, L.4
Arnold, A.5
Davis, M.6
Tonato, M.7
Smylie, M.8
Tu, D.9
Voi, M.10
Humphrey, J.11
Ottaway, J.12
Young, K.13
Vreckem, A.V.14
Seymour, L.15
-
69
-
-
21044453902
-
Randomized phase III study of matrix metalloproteinase inhibitor BMS-275291 in combination with paclitaxel and carboplatin in advanced non-small-cell lung cancer: National Cancer Institute of Canada-Clinical Trials Group Study BR.18
-
Leighl, N. B.; Paz-Ares, L.; Douillard, J. Y.; Peschel, C.; Arnold, A.; Depierre, A.; Santoro, A.; Betticher, D. C.; Gatzemeier, U.; Jassem, J.; Crawford, J.; Tu, D.; Bezjak, A.; Humphrey, J. S.; Voi, M.; Galbraith, S.; Hann, K.; Seymour, L.; Shepherd, F. A., Randomized phase III study of matrix metalloproteinase inhibitor BMS-275291 in combination with paclitaxel and carboplatin in advanced non-small-cell lung cancer: National Cancer Institute of Canada-Clinical Trials Group Study BR.18. J. Clin. Oncol., 2005, 23 (12), 2831-2839.
-
(2005)
J. Clin. Oncol
, vol.23
, Issue.12
, pp. 2831-2839
-
-
Leighl, N.B.1
Paz-Ares, L.2
Douillard, J.Y.3
Peschel, C.4
Arnold, A.5
Depierre, A.6
Santoro, A.7
Betticher, D.C.8
Gatzemeier, U.9
Jassem, J.10
Crawford, J.11
Tu, D.12
Bezjak, A.13
Humphrey, J.S.14
Voi, M.15
Galbraith, S.16
Hann, K.17
Seymour, L.18
Shepherd, F.A.19
-
70
-
-
0029688549
-
Matrix metalloproteinases and their inhibition in periodontal treatment
-
Ryan, M. E.; Ramamurthy, S.; Golub, L. M., Matrix metalloproteinases and their inhibition in periodontal treatment. Curr Opin Periodontol 1996, 3, 85-96.
-
(1996)
Curr Opin Periodontol
, vol.3
, pp. 85-96
-
-
Ryan, M.E.1
Ramamurthy, S.2
Golub, L.M.3
-
71
-
-
0032200444
-
Tetracyclines inhibit connective tissue breakdown by multiple non-antimicrobial mechanisms
-
Golub, L. M.; Lee, H. M.; Ryan, M. E.; Giannobile, W. V.; Payne, J.; Sorsa, T., Tetracyclines inhibit connective tissue breakdown by multiple non-antimicrobial mechanisms. Adv. Dent. Res., 1998, 12 (2), 12-26.
-
(1998)
Adv. Dent. Res
, vol.12
, Issue.2
, pp. 12-26
-
-
Golub, L.M.1
Lee, H.M.2
Ryan, M.E.3
Giannobile, W.V.4
Payne, J.5
Sorsa, T.6
-
72
-
-
0032864675
-
MMP inhibition in prostate cancer
-
Lokeshwar, B. L., MMP inhibition in prostate cancer. Ann. NY Acad. Sci., 1999, 878, 271-289.
-
(1999)
Ann. NY Acad. Sci
, vol.878
, pp. 271-289
-
-
Lokeshwar, B.L.1
-
73
-
-
0031281806
-
Inhibition of proliferation and induction of apoptosis by doxycycline in cultured human osteosarcoma cells
-
Fife, R. S.; Rougraff, B. T.; Proctor, C.; Sledge, G. W., Jr., Inhibition of proliferation and induction of apoptosis by doxycycline in cultured human osteosarcoma cells. J Lab Clin Med 1997, 130 (5), 530-534.
-
(1997)
J Lab Clin Med
, vol.130
, Issue.5
, pp. 530-534
-
-
Fife, R.S.1
Rougraff, B.T.2
Proctor, C.3
Sledge Jr., G.W.4
-
74
-
-
0031920784
-
Chemically modified tetracyclines inhibit human melanoma cell invasion and metastasis
-
Seftor, R. E.; Seftor, E. A.; De Larco, J. E.; Kleiner, D. E.; Leferson, J.; Stetler-Stevenson, W. G.; McNamara, T. F.; Golub, L. M.; Hendrix, M. J., Chemically modified tetracyclines inhibit human melanoma cell invasion and metastasis. Clin. Exp. Metastasis, 1998, 16 (3), 217-225.
-
(1998)
Clin. Exp. Metastasis
, vol.16
, Issue.3
, pp. 217-225
-
-
Seftor, R.E.1
Seftor, E.A.2
de Larco, J.E.3
Kleiner, D.E.4
Leferson, J.5
Stetler-Stevenson, W.G.6
McNamara, T.F.7
Golub, L.M.8
Hendrix, M.J.9
-
75
-
-
0031973365
-
In vitro sensitivity of the three mammalian collagenases to tetracycline inhibition: Relationship to bone and cartilage degradation
-
Greenwald, R. A.; Golub, L. M.; Ramamurthy, N. S.; Chowdhury, M.; Moak, S. A.; Sorsa, T., In vitro sensitivity of the three mammalian collagenases to tetracycline inhibition: relationship to bone and cartilage degradation. Bone, 1998, 22 (1), 33-38.
-
(1998)
Bone
, vol.22
, Issue.1
, pp. 33-38
-
-
Greenwald, R.A.1
Golub, L.M.2
Ramamurthy, N.S.3
Chowdhury, M.4
Moak, S.A.5
Sorsa, T.6
-
76
-
-
0029146734
-
The tetracycline analogs minocycline and doxycycline inhibit angiogenesis in vitro by a nonmetalloproteinase-dependent mechanism
-
Gilbertson-Beadling, S.; Powers, E. A.; Stamp-Cole, M.; Scott, P. S.; Wallace, T. L.; Copeland, J.; Petzold, G.; Mitchell, M.; Ledbetter, S.; Poorman, R., The tetracycline analogs minocycline and doxycycline inhibit angiogenesis in vitro by a nonmetalloproteinase- dependent mechanism. Cancer Chemother. Pharmacol., 1995, 36 (5), 418-424.
-
(1995)
Cancer Chemother. Pharmacol
, vol.36
, Issue.5
, pp. 418-424
-
-
Gilbertson-Beadling, S.1
Powers, E.A.2
Stamp-Cole, M.3
Scott, P.S.4
Wallace, T.L.5
Copeland, J.6
Petzold, G.7
Mitchell, M.8
Ledbetter, S.9
Poorman, R.10
-
77
-
-
0344483895
-
Specificity of inhibition of matrix metalloproteinase activity by doxycycline: Relationship to structure of the enzyme
-
Smith, G. N., Jr.; Mickler, E. A.; Hasty, K. A.; Brandt, K. D., Specificity of inhibition of matrix metalloproteinase activity by doxycycline: relationship to structure of the enzyme. Arthritis Rheum., 1999, 42 (6), 1140-1146.
-
(1999)
Arthritis Rheum
, vol.42
, Issue.6
, pp. 1140-1146
-
-
Smith Jr., G.N.1
Mickler, E.A.2
Hasty, K.A.3
Brandt, K.D.4
-
78
-
-
0029257434
-
Effects of doxycycline on in vitro growth, migration, and gelatinase activity of breast carcinoma cells
-
Fife, R. S.; Sledge, G. W., Jr., Effects of doxycycline on in vitro growth, migration, and gelatinase activity of breast carcinoma cells. J. Lab. Clin. Med., 1995, 125 (3), 407-411.
-
(1995)
J. Lab. Clin. Med
, vol.125
, Issue.3
, pp. 407-411
-
-
Fife, R.S.1
Sledge Jr., G.W.2
-
79
-
-
0032983385
-
Transforming growth factor beta1 acts as an inducer of matrix metalloproteinase expression and activity in human bone-metastasizing cancer cells
-
Duivenvoorden, W. C.; Hirte, H. W.; Singh, G., Transforming growth factor beta1 acts as an inducer of matrix metalloproteinase expression and activity in human bone-metastasizing cancer cells. Clin Exp Metastasis 1999, 17 (1), 27-34.
-
(1999)
Clin Exp Metastasis
, vol.17
, Issue.1
, pp. 27-34
-
-
Duivenvoorden, W.C.1
Hirte, H.W.2
Singh, G.3
-
80
-
-
0032523857
-
Effects of doxycycline on human prostate cancer cells in vitro
-
Fife, R. S.; Sledge, G. W., Jr.; Roth, B. J.; Proctor, C., Effects of doxycycline on human prostate cancer cells in vitro. Cancer Lett., 1998, 127 (1/2), 37-41.
-
(1998)
Cancer Lett
, vol.127
, Issue.1-2
, pp. 37-41
-
-
Fife, R.S.1
Sledge Jr., G.W.2
Roth, B.J.3
Proctor, C.4
-
81
-
-
0031545846
-
Use of tetracycline as an inhibitor of matrix metalloproteinase activity secreted by human bone-metastasizing cancer cells
-
Duivenvoorden, W. C.; Hirte, H. W.; Singh, G., Use of tetracycline as an inhibitor of matrix metalloproteinase activity secreted by human bone-metastasizing cancer cells. Invasion Metastasis, 1997, 17 (6), 312-322.
-
(1997)
Invasion Metastasis
, vol.17
, Issue.6
, pp. 312-322
-
-
Duivenvoorden, W.C.1
Hirte, H.W.2
Singh, G.3
-
82
-
-
0028889359
-
Effect of matrix metalloproteinase inhibitor batimastat on breast cancer regrowth and metastasis in athymic mice
-
Sledge, G. W., Jr.; Qulali, M.; Goulet, R.; Bone, E. A.; Fife, R., Effect of matrix metalloproteinase inhibitor batimastat on breast cancer regrowth and metastasis in athymic mice. J. Natl. Cancer Inst., 1995, 87 (20), 1546-1550.
-
(1995)
J. Natl. Cancer Inst
, vol.87
, Issue.20
, pp. 1546-1550
-
-
Sledge Jr., G.W.1
Qulali, M.2
Goulet, R.3
Bone, E.A.4
Fife, R.5
-
84
-
-
0035036501
-
CMT-3, a non-antimicrobial tetracycline (TC), inhibits MT1-MMP activity: Relevance to cancer
-
Lee, H. M.; Golub, L. M.; Cao, J.; Teronen, O.; Laitinen, M.; Salo, T.; Zucker, S.; Sorsa, T., CMT-3, a non-antimicrobial tetracycline (TC), inhibits MT1-MMP activity: relevance to cancer. Curr. Med. Chem., 2001, 8 (3), 257-260.
-
(2001)
Curr. Med. Chem
, vol.8
, Issue.3
, pp. 257-260
-
-
Lee, H.M.1
Golub, L.M.2
Cao, J.3
Teronen, O.4
Laitinen, M.5
Salo, T.6
Zucker, S.7
Sorsa, T.8
-
85
-
-
0032837305
-
CMT-3, a chemically modified tetracycline, inhibits bony metastases and delays the development of paraplegia in a rat model of prostate cancer
-
Selzer, M. G.; Zhu, B.; Block, N. L.; Lokeshwar, B. L., CMT-3, a chemically modified tetracycline, inhibits bony metastases and delays the development of paraplegia in a rat model of prostate cancer. Ann. NY Acad. Sci., 1999, 878, 678-682.
-
(1999)
Ann. NY Acad. Sci
, vol.878
, pp. 678-682
-
-
Selzer, M.G.1
Zhu, B.2
Block, N.L.3
Lokeshwar, B.L.4
-
86
-
-
79251636716
-
Chemically modified non-antimicrobial tetracyclines are multifunctional drugs against advanced cancers
-
Lokeshwar, B. L., Chemically modified non-antimicrobial tetracyclines are multifunctional drugs against advanced cancers. Pharmacol. Res., 2011, 63 (2), 146-150.
-
(2011)
Pharmacol. Res
, vol.63
, Issue.2
, pp. 146-150
-
-
Lokeshwar, B.L.1
-
87
-
-
80054096571
-
Chemically modified tetracycline-3 (CMT-3): A novel inhibitor of the serine proteinase, elastase
-
Gu, Y.; Lee, H. M.; Simon, S. R.; Golub, L. M., Chemically modified tetracycline-3 (CMT-3): A novel inhibitor of the serine proteinase, elastase. Pharmacol. Res., 2011.
-
(2011)
Pharmacol. Res
-
-
Gu, Y.1
Lee, H.M.2
Simon, S.R.3
Golub, L.M.4
-
88
-
-
5444229881
-
A phase I and pharmacokinetic study of Col-3 (Metastat), an oral tetracycline derivative with potent matrix metalloproteinase and antitumor properties
-
Syed, S.; Takimoto, C.; Hidalgo, M.; Rizzo, J.; Kuhn, J. G.; Hammond, L. A.; Schwartz, G.; Tolcher, A.; Patnaik, A.; Eckhardt, S. G.; Rowinsky, E. K., A phase I and pharmacokinetic study of Col-3 (Metastat), an oral tetracycline derivative with potent matrix metalloproteinase and antitumor properties. Clin. Cancer Res., 2004, 10 (19), 6512-6521.
-
(2004)
Clin. Cancer Res
, vol.10
, Issue.19
, pp. 6512-6521
-
-
Syed, S.1
Takimoto, C.2
Hidalgo, M.3
Rizzo, J.4
Kuhn, J.G.5
Hammond, L.A.6
Schwartz, G.7
Tolcher, A.8
Patnaik, A.9
Eckhardt, S.G.10
Rowinsky, E.K.11
-
89
-
-
0035863463
-
Phase I clinical trial of oral COL-3, a matrix metalloproteinase inhibitor, in patients with refractory metastatic cancer
-
Rudek, M. A.; Figg, W. D.; Dyer, V.; Dahut, W.; Turner, M. L.; Steinberg, S. M.; Liewehr, D. J.; Kohler, D. R.; Pluda, J. M.; Reed, E., Phase I clinical trial of oral COL-3, a matrix metalloproteinase inhibitor, in patients with refractory metastatic cancer. J Clin Oncol 2001, 19 (2), 584-592.
-
(2001)
J Clin Oncol
, vol.19
, Issue.2
, pp. 584-592
-
-
Rudek, M.A.1
Figg, W.D.2
Dyer, V.3
Dahut, W.4
Turner, M.L.5
Steinberg, S.M.6
Liewehr, D.J.7
Kohler, D.R.8
Pluda, J.M.9
Reed, E.10
-
90
-
-
0036137547
-
Matrix metalloproteinase inhibitor COL-3 in the treatment of AIDS-related Kaposi's sarcoma: A phase I AIDS malignancy consortium study
-
Cianfrocca, M.; Cooley, T. P.; Lee, J. Y.; Rudek, M. A.; Scadden, D. T.; Ratner, L.; Pluda, J. M.; Figg, W. D.; Krown, S. E.; Dezube, B. J., Matrix metalloproteinase inhibitor COL-3 in the treatment of AIDS-related Kaposi's sarcoma: a phase I AIDS malignancy consortium study. J. Clin. Oncol., 2002, 20 (1), 153-159.
-
(2002)
J. Clin. Oncol
, vol.20
, Issue.1
, pp. 153-159
-
-
Cianfrocca, M.1
Cooley, T.P.2
Lee, J.Y.3
Rudek, M.A.4
Scadden, D.T.5
Ratner, L.6
Pluda, J.M.7
Figg, W.D.8
Krown, S.E.9
Dezube, B.J.10
-
91
-
-
34250630512
-
A phase II and pharmacological study of the matrix metalloproteinase inhibitor (MMPI) COL-3 in patients with advanced soft tissue sarcomas
-
Chu, S. C.; Forouzesh, B.; Syed, S.; Mita, M.; Schwartz, G.; Copper, J.; Curtright, J.; Rowinsky, E.K. A phase II and pharmacological study of the matrix metalloproteinase inhibitor (MMPI) COL-3 in patients with advanced soft tissue sarcomas. Invest. New Drugs, 2007, 25, 359-367.
-
(2007)
Invest. New Drugs
, vol.25
, pp. 359-367
-
-
Chu, S.C.1
Forouzesh, B.2
Syed, S.3
Mita, M.4
Schwartz, G.5
Copper, J.6
Curtright, J.7
Rowinsky, E.K.8
-
92
-
-
33750733277
-
Molecular mechanisms of action of bisphosphonates: Current status
-
Roelofs, A. J.; Thompson, K.; Gordon, S.; Rogers, M. J., Molecular mechanisms of action of bisphosphonates: current status. Clin. Cancer Res., 2006, 12 (20 Pt 2), 6222s-6230s.
-
(2006)
Clin. Cancer Res
, vol.12
, Issue.20 PT 2
-
-
Roelofs, A.J.1
Thompson, K.2
Gordon, S.3
Rogers, M.J.4
-
93
-
-
43049142648
-
Matrix metalloproteinase inhibitors as anticancer agents
-
Konstantinopoulos, P. A.; Karamouzis, M. V.; Papatsoris, A. G.; Papavassiliou, A. G., Matrix metalloproteinase inhibitors as anticancer agents. Int. J.Biochem. Cell Biol., 2008, 40 (6-7),1156-1168.
-
(2008)
Int. J.Biochem. Cell Biol
, vol.40
, Issue.6-7
, pp. 1156-1168
-
-
Konstantinopoulos, P.A.1
Karamouzis, M.V.2
Papatsoris, A.G.3
Papavassiliou, A.G.4
-
94
-
-
0032428103
-
Alendronate blocks metalloproteinase secretion and bone collagen I release by PC-3 ML cells in SCID mice
-
Stearns, M. E.; Wang, M., Alendronate blocks metalloproteinase secretion and bone collagen I release by PC-3 ML cells in SCID mice. Clin Exp Metastasis 1998, 16 (8), 693-702.
-
(1998)
Clin Exp Metastasis
, vol.16
, Issue.8
, pp. 693-702
-
-
Stearns, M.E.1
Wang, M.2
-
95
-
-
0031803029
-
Alendronate blocks TGF-beta1 stimulated collagen 1 degradation by human prostate PC-3 ML cells
-
Stearns, M. E., Alendronate blocks TGF-beta1 stimulated collagen 1 degradation by human prostate PC-3 ML cells. Clin. Exp. Metastasis, 1998, 16 (4), 332-339.
-
(1998)
Clin. Exp. Metastasis
, vol.16
, Issue.4
, pp. 332-339
-
-
Stearns, M.E.1
-
96
-
-
0032863323
-
MMP inhibition and downregulation by bisphosphonates
-
Teronen, O.; Heikkila, P.; Konttinen, Y. T.; Laitinen, M.; Salo, T.; Hanemaaijer, R.; Teronen, A.; Maisi, P.; Sorsa, T., MMP inhibition and downregulation by bisphosphonates. Ann. NY Acad. Sci., 1999, 878, 453-465.
-
(1999)
Ann. NY Acad. Sci
, vol.878
, pp. 453-465
-
-
Teronen, O.1
Heikkila, P.2
Konttinen, Y.T.3
Laitinen, M.4
Salo, T.5
Hanemaaijer, R.6
Teronen, A.7
Maisi, P.8
Sorsa, T.9
-
97
-
-
2442713986
-
Carbamoylphosphonates, a new class of in vivo active matrix metalloproteinase inhibitors. 1. Alkyl- and cycloalkylcarbamoylphosphonic acids
-
Breuer, E.; Salomon, C. J.; Katz, Y.; Chen, W.; Lu, S.; Roschenthaler, G. V.; Hadar, R.; Reich, R., Carbamoylphosphonates, a new class of in vivo active matrix metalloproteinase inhibitors. 1. Alkyl- and cycloalkylcarbamoylphosphonic acids. J. Med. Chem., 2004, 47 (11), 2826-2832.
-
(2004)
J. Med. Chem
, vol.47
, Issue.11
, pp. 2826-2832
-
-
Breuer, E.1
Salomon, C.J.2
Katz, Y.3
Chen, W.4
Lu, S.5
Roschenthaler, G.V.6
Hadar, R.7
Reich, R.8
-
98
-
-
2342624494
-
Carbamoylphosphonate-based matrix metalloproteinase inhibitor metal complexes: Solution studies and stability constants. Towards a zinc-selective binding group
-
Farkas, E.; Katz, Y.; Bhusare, S.; Reich, R.; Roschenthaler, G. V.; Konigsmann, M.; Breuer, E., Carbamoylphosphonate-based matrix metalloproteinase inhibitor metal complexes: solution studies and stability constants. Towards a zinc-selective binding group. J. Biol. Inorg. Chem., 2004, 9 (3), 307-315.
-
(2004)
J. Biol. Inorg. Chem
, vol.9
, Issue.3
, pp. 307-315
-
-
Farkas, E.1
Katz, Y.2
Bhusare, S.3
Reich, R.4
Roschenthaler, G.V.5
Konigsmann, M.6
Breuer, E.7
-
99
-
-
18844424018
-
Carbamoylphosphonate matrix metalloproteinase inhibitors 3: In vivo evaluation of cyclopentylcarbamoylphosphonic acid in experimental metastasis and angiogenesis
-
Reich, R.; Katz, Y.; Hadar, R.; Breuer, E., Carbamoylphosphonate matrix metalloproteinase inhibitors 3: in vivo evaluation of cyclopentylcarbamoylphosphonic acid in experimental metastasis and angiogenesis. Clin. Cancer Res., 2005, 11 (10), 3925-3929.
-
(2005)
Clin. Cancer Res
, vol.11
, Issue.10
, pp. 3925-3929
-
-
Reich, R.1
Katz, Y.2
Hadar, R.3
Breuer, E.4
-
100
-
-
41349106390
-
Carbamoylphosphonate matrix metalloproteinase inhibitors 6: Cis-2-aminocyclohexylcarbamoylphosphonic acid, a novel orally active antimetastatic matrix metalloproteinase-2 selective inhibitor--synthesis and pharmacodynamic and pharmacokinetic analysis
-
Hoffman, A.; Qadri, B.; Frant, J.; Katz, Y.; Bhusare, S. R.; Breuer, E.; Hadar, R.; Reich, R., Carbamoylphosphonate matrix metalloproteinase inhibitors 6: cis-2-aminocyclohexylcarbamoylphosphonic acid, a novel orally active antimetastatic matrix metalloproteinase-2 selective inhibitor--synthesis and pharmacodynamic and pharmacokinetic analysis. J. Med. Chem., 2008, 51 (5), 1406-1414.
-
(2008)
J. Med. Chem
, vol.51
, Issue.5
, pp. 1406-1414
-
-
Hoffman, A.1
Qadri, B.2
Frant, J.3
Katz, Y.4
Bhusare, S.R.5
Breuer, E.6
Hadar, R.7
Reich, R.8
-
101
-
-
77149131528
-
To bind zinc or not to bind zinc: An examination of innovative approaches to improved metalloproteinase inhibition
-
Jacobsen, J. A.; Major Jourden, J. L.; Miller, M. T.; Cohen, S. M., To bind zinc or not to bind zinc: an examination of innovative approaches to improved metalloproteinase inhibition. Biochim. Biophys. Acta, 2010, 1803 (1), 72-94.
-
(2010)
Biochim. Biophys. Acta
, vol.1803
, Issue.1
, pp. 72-94
-
-
Jacobsen, J.A.1
Major Jourden, J.L.2
Miller, M.T.3
Cohen, S.M.4
-
102
-
-
77749319354
-
Lost in migration
-
Mack, G. S.; Marshall, A., Lost in migration. Nat. Biotechnol., 2010, 28 (3), 214-229.
-
(2010)
Nat. Biotechnol
, vol.28
, Issue.3
, pp. 214-229
-
-
Mack, G.S.1
Marshall, A.2
-
103
-
-
79551688936
-
A peptidomimetic inhibitor of matrix metalloproteinases containing a tetherable linker group
-
Cao, Y.; Croll, T. I.; Rizzi, S. C.; Shooter, G. K.; Edwards, H.; Finlayson, K.; Upton, Z.; Dargaville, T. R., A peptidomimetic inhibitor of matrix metalloproteinases containing a tetherable linker group. J. Biomed. Mater. Res. A, 2011, 96 (4), 663-672.
-
(2011)
J. Biomed. Mater. Res. A
, vol.96
, Issue.4
, pp. 663-672
-
-
Cao, Y.1
Croll, T.I.2
Rizzi, S.C.3
Shooter, G.K.4
Edwards, H.5
Finlayson, K.6
Upton, Z.7
Dargaville, T.R.8
-
104
-
-
36849073658
-
MMPs as therapeutic targets--still a viable option?
-
Fingleton, B., MMPs as therapeutic targets--still a viable option? Semin. Cell Dev. Biol., 2008, 19 (1), 61-68.
-
(2008)
Semin. Cell Dev. Biol
, vol.19
, Issue.1
, pp. 61-68
-
-
Fingleton, B.1
-
105
-
-
0036512208
-
New functions for the matrix metalloproteinases in cancer progression
-
Egeblad, M.; Werb, Z., New functions for the matrix metalloproteinases in cancer progression. Nat. Rev. Cancer, 2002, 2 (3), 161-174.
-
(2002)
Nat. Rev. Cancer
, vol.2
, Issue.3
, pp. 161-174
-
-
Egeblad, M.1
Werb, Z.2
-
106
-
-
60649108677
-
Selective inhibition of matrix metalloproteinase-14 blocks tumor growth, invasion, and angiogenesis
-
Devy, L.; Huang, L.; Naa, L.; Yanamandra, N.; Pieters, H.; Frans, N.; Chang, E.; Tao, Q.; Vanhove, M.; Lejeune, A.; van Gool, R.; Sexton, D. J.; Kuang, G.; Rank, D.; Hogan, S.; Pazmany, C.; Ma, Y. L.; Schoonbroodt, S.; Nixon, A. E.; Ladner, R. C.; Hoet, R.; Henderikx, P.; Tenhoor, C.; Rabbani, S. A.; Valentino, M. L.; Wood, C. R.; Dransfield, D. T., Selective inhibition of matrix metalloproteinase-14 blocks tumor growth, invasion, and angiogenesis. Cancer Res., 2009, 69 (4), 1517-1526.
-
(2009)
Cancer Res
, vol.69
, Issue.4
, pp. 1517-1526
-
-
Devy, L.1
Huang, L.2
Naa, L.3
Yanamandra, N.4
Pieters, H.5
Frans, N.6
Chang, E.7
Tao, Q.8
Vanhove, M.9
Lejeune, A.10
van Gool, R.11
Sexton, D.J.12
Kuang, G.13
Rank, D.14
Hogan, S.15
Pazmany, C.16
Ma, Y.L.17
Schoonbroodt, S.18
Nixon, A.E.19
Ladner, R.C.20
Hoet, R.21
Henderikx, P.22
Tenhoor, C.23
Rabbani, S.A.24
Valentino, M.L.25
Wood, C.R.26
Dransfield, D.T.27
more..
-
107
-
-
34250849091
-
Matrix metalloproteinases: New routes to the use of MT1-MMP as a therapeutic target in angiogenesis-related disease
-
Arroyo, A. G.; Genis, L.; Gonzalo, P.; Matias-Roman, S.; Pollan, A.; Galvez, B. G., Matrix metalloproteinases: new routes to the use of MT1-MMP as a therapeutic target in angiogenesis-related disease. Curr. Pharm. Des., 2007, 13 (17), 1787-1802.
-
(2007)
Curr. Pharm. Des
, vol.13
, Issue.17
, pp. 1787-1802
-
-
Arroyo, A.G.1
Genis, L.2
Gonzalo, P.3
Matias-Roman, S.4
Pollan, A.5
Galvez, B.G.6
-
108
-
-
34250307200
-
MT1- MMP controls tumor-induced angiogenesis through the release of semaphorin 4D
-
Basile, J. R.; Holmbeck, K.; Bugge, T. H.; Gutkind, J. S., MT1- MMP controls tumor-induced angiogenesis through the release of semaphorin 4D. J. Biol. Chem., 2007, 282 (9), 6899-6905.
-
(2007)
J. Biol. Chem
, vol.282
, Issue.9
, pp. 6899-6905
-
-
Basile, J.R.1
Holmbeck, K.2
Bugge, T.H.3
Gutkind, J.S.4
-
109
-
-
77954897099
-
Metalloproteinase binding proteins: WO2009097397
-
Itoh, Y., Metalloproteinase binding proteins: WO2009097397. Expert. Opin. Ther. Pat., 2010, 20 (8), 1091-1095.
-
(2010)
Expert. Opin. Ther. Pat
, vol.20
, Issue.8
, pp. 1091-1095
-
-
Itoh, Y.1
-
110
-
-
76749106583
-
Isolation and characterization of human monoclonal antibodies specific to MMP- 1A, MMP-2 and MMP-3
-
Pfaffen, S.; Hemmerle, T.; Weber, M.; Neri, D., Isolation and characterization of human monoclonal antibodies specific to MMP- 1A, MMP-2 and MMP-3. Exp. Cell Res., 2010, 316 (5), 836-847.
-
(2010)
Exp. Cell Res
, vol.316
, Issue.5
, pp. 836-847
-
-
Pfaffen, S.1
Hemmerle, T.2
Weber, M.3
Neri, D.4
-
111
-
-
77956154773
-
Tumourtargeting properties of antibodies specific to MMP-1A, MMP-2 and MMP-3
-
Pfaffen, S.; Frey, K.; Stutz, I.; Roesli, C.; Neri, D., Tumourtargeting properties of antibodies specific to MMP-1A, MMP-2 and MMP-3. Eur. J. Nucl. Med. Mol. Imaging, 2010, 37 (8), 1559-1565.
-
(2010)
Eur. J. Nucl. Med. Mol. Imaging
, vol.37
, Issue.8
, pp. 1559-1565
-
-
Pfaffen, S.1
Frey, K.2
Stutz, I.3
Roesli, C.4
Neri, D.5
-
112
-
-
0034722889
-
The EGF receptor family as targets for cancer therapy
-
Mendelsohn, J.; Baselga, J., The EGF receptor family as targets for cancer therapy. Oncogene, 2000, 19 (56), 6550-6565.
-
(2000)
Oncogene
, vol.19
, Issue.56
, pp. 6550-6565
-
-
Mendelsohn, J.1
Baselga, J.2
-
113
-
-
34250172746
-
Monoclonal antibody 4C5 immunostains human melanomas and inhibits melanoma cell invasion and metastasis
-
Stellas, D.; Karameris, A.; Patsavoudi, E., Monoclonal antibody 4C5 immunostains human melanomas and inhibits melanoma cell invasion and metastasis. Clin. Cancer Res., 2007, 13 (6), 1831-1838.
-
(2007)
Clin. Cancer Res
, vol.13
, Issue.6
, pp. 1831-1838
-
-
Stellas, D.1
Karameris, A.2
Patsavoudi, E.3
-
114
-
-
38349132541
-
A critical role for HSP90 in cancer cell invasion involves interaction with the extracellular domain of HER-2
-
Sidera, K.; Gaitanou, M.; Stellas, D.; Matsas, R.; Patsavoudi, E., A critical role for HSP90 in cancer cell invasion involves interaction with the extracellular domain of HER-2. J. Biol. Chem., 2008, 283 (4), 2031-2041.
-
(2008)
J. Biol. Chem
, vol.283
, Issue.4
, pp. 2031-2041
-
-
Sidera, K.1
Gaitanou, M.2
Stellas, D.3
Matsas, R.4
Patsavoudi, E.5
|