-
5
-
-
19244366949
-
Phase I studies of anti-epidermal growth factor receptor chimeric antibody C225 alone and in combination with cisplatin
-
(2000)
Journal of Clinical Oncology
, vol.18
, pp. 904-914
-
-
Baselga, J.1
Pfister, D.2
Cooper, M.R.3
Cohen, R.4
Burtness, B.5
Bos, M.6
D'Andrea, G.7
Seidman, A.8
Norton, L.9
Gunnett, K.10
Anderson, V.11
Waksal, H.12
Mendelsohn, J.13
-
7
-
-
0030697807
-
PD 153035, a tyrosine kinase inhibitor, prevents receptor activation and inhibits growth of cancer cells overexpressing the epidermal growth factor receptor in a dose and receptor number dependent manner
-
(1997)
Clinical Cancer Research
, vol.3
, pp. 2099-2106
-
-
Bos, M.1
Mendelsohn, J.2
Kim, Y.M.3
Albanell, J.4
Fry, D.W.5
Baselga, J.6
-
8
-
-
18844473781
-
Epidermal growth factor receptor blockade with C225 plus gemcitabine results in regression of human pancreatic carcinoma growing orthotopically in nude mice by anti-angiogenic mechanisms
-
(2000)
Clinical Cancer Research
, vol.6
, pp. 1936-1948
-
-
Bruns, C.J.1
Harbison, M.T.2
Davis, D.W.3
Portera, C.A.4
Tsan, R.5
McConkey, D.J.6
Evans, D.B.7
Abbruzzese, J.L.8
Hicklin, D.J.9
Radinsky, R.10
-
9
-
-
0001076235
-
1 arrest and enhancing the antitumor effect of interferon
-
(2000)
Proceedings of the Annual Meeting of the American Association for Cancer Research
, vol.41
-
-
Budillon, A.1
Di Gennaro, E.2
Barbarino, M.3
Bruzzese, F.4
De Lorenzo, S.5
Pepe, S.6
Tagliaferri, P.7
Abbruzzese, A.8
Caragllia, M.9
Caponigro, F.10
-
10
-
-
0034629485
-
Reversible G(1) arrest induced by inhibition of the epidermal growth factor receptor tyrosine kinase requires up-regulation of p27(KIP1) independent of MAPK activity
-
(2000)
Journal of Biological Chemistry
, vol.275
, pp. 6987-6995
-
-
Busse, D.1
Doughty, R.S.2
Ramsey, T.T.3
Russell, W.E.4
Price, J.O.5
Flanagan, W.M.6
Shawver, L.K.7
Arteaga, C.L.8
-
11
-
-
0019829559
-
Purified EGF receptor-kinase interacts specifically with antibodies to Rous sarcoma virus transforming protein
-
(1981)
Nature
, vol.290
, pp. 516-519
-
-
Chinkers, M.1
Cohen, S.2
-
13
-
-
0032904485
-
Antitumor activity of sequential treatment with Topotecan and anti-epidermal growth factor receptor monoclonal antibody C225
-
(1999)
Clinical Cancer Research
, vol.5
, pp. 909-916
-
-
Ciardiello, F.1
Bianco, R.2
Damiano, V.3
De Lorenzo, S.4
Pepe, S.5
De Placido, S.6
Fan, Z.7
Mendelsohn, J.8
Bianco, A.R.9
Tortora, G.10
-
15
-
-
84916265276
-
Isolation of a mouse submaxillary gland protein accelerating incisor eruption and eyelid opening in the new born animal
-
(1962)
Journal of Biological Chemistry
, vol.237
, pp. 1555-1562
-
-
Cohen, S.1
-
18
-
-
0021281324
-
Close similarity of epidermal growth factor receptor and v-erb-B oncogene protein sequences
-
(1984)
Nature
, vol.307
, pp. 521-527
-
-
Downward, J.1
Yarden, Y.2
Mayes, E.3
Scrace, G.4
Totty, N.5
Stockwell, P.6
Ullrich, A.7
Schlessinger, J.8
Waterfield, M.D.9
-
20
-
-
0026642195
-
Induction of apoptosis in fibroblasts by c-myc protein
-
(1992)
Cell
, vol.69
, pp. 119-128
-
-
Evan, G.I.1
Wyllie, A.H.2
Gilbert, C.S.3
Littlewood, T.D.4
Land, H.5
Brooks, M.6
Waters, C.M.7
Penn, L.Z.8
Hancock, D.C.9
-
21
-
-
0002790803
-
Phase I study of anti-epidermal growth factor receptor (EGFR) antibody C225 in combination with irradiation in patients with advanced squamous cell carcinoma of the head and neck (SCCHN)
-
(1998)
Proceedings of the Annual Meeting of the American Society for Clinical Oncology
, vol.17
-
-
Ezekiel, M.P.1
Robert, F.2
Meredith, R.F.3
Spencer, S.A.4
Newsome, J.5
Khazaeli, M.B.6
Peters, G.E.7
Saleh, M.8
LoBuglio, A.F.9
Waksal, H.10
-
25
-
-
0002200965
-
Intermittent oral ZD1839 (Iressa), a novel epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI), shows evidence of good tolerability and activity: Final results from a phase I study
-
(2000)
Proceedings of the Annual Meeting of the American Society for Clinical Oncology
, vol.19
-
-
Ferry, D.1
Hammond, L.2
Ranson, M.3
Kris, M.4
Miller, V.5
Murray, P.6
Tullo, A.7
Feyereislova, A.8
Averbuch, S.9
Rowinsky, E.10
-
27
-
-
0028142387
-
A specific inhibitor of the epidermal growth factor receptor tyrosine kinase
-
(1994)
Science
, vol.265
, pp. 1093-1095
-
-
Fry, D.W.1
Kraker, A.J.2
McMichael, A.3
Ambroso, L.A.4
Nelson, J.M.5
Leopold, W.R.6
Connors, R.W.7
Bridges, A.J.8
-
28
-
-
13144266690
-
Specific, irreversible inactivation of the epidermal growth factor receptor and erbB2, by a new class of tyrosine kinase inhibitor
-
(1998)
PNAS
, vol.95
, pp. 12022-12027
-
-
Fry, D.W.1
Bridges, A.J.2
Denny, W.A.3
Doherty, A.4
Greis, K.D.5
Hicks, J.L.6
Hook, K.E.7
Keller, P.R.8
Leopold, W.R.9
Loo, J.A.10
McNamara, D.J.11
Nelson, J.M.12
Sherwood, V.13
Smaill, J.B.14
Trumpp-Kallmeyer, S.15
Dobrusin, E.M.16
-
29
-
-
0021254542
-
Monoclonal anti-epidermal growth factor receptor antibodies which are inhibitors of epidermal growth factor binding and antagonists of epidermal growth factor-stimulated tyrosine protein kinase activity
-
(1984)
Journal of Biological Chemistry
, vol.259
, pp. 7755-7760
-
-
Gill, G.N.1
Kawamoto, T.2
Cochet, C.3
Le, A.4
Sato, J.D.5
Masui, H.6
McLeod, C.7
Mendelsohn, J.8
-
32
-
-
0033561522
-
Epidermal growth factor receptor blockade with C225 modulates proliferation, apoptosis, and radiosensitivity in squamous cell carcinomas of the head and neck
-
(1999)
Cancer Research
, vol.59
, pp. 1935-1940
-
-
Huang, S.M.1
Bock, J.M.2
Harari, P.M.3
-
38
-
-
0021257637
-
Expression cloning of human EGF receptor complementary DNA: Gene amplification and three related messenger RNA products in A431 cells
-
(1984)
Science
, vol.224
, pp. 843-848
-
-
Lin, C.R.1
Chen, W.S.2
Kruiger, W.3
Stolarsky, L.S.4
Weber, W.5
Evans, R.M.6
Verma, I.M.7
Gill, G.N.8
Rosenfeld, M.G.9
-
46
-
-
0001680408
-
A phase I study of chimerized anti-epidermal growth factor receptor (EGFr) monoclonal antibody, C225, in combination with cisplatin (CDDP) in patients (pts) with recurrent head and neck squamous cell carcinoma (SCC)
-
(1999)
Proceedings of the Annual Meeting of the American Society for Clinical Oncology
, vol.18
-
-
Mendelsohn, J.1
Shin, D.M.2
Donato, N.3
Khuri, F.4
Radinsky, R.5
Glisson, B.S.6
Shin, H.J.7
Metz, E.8
Pfister, D.9
Perez-Soler, R.10
Lawhorn, K.11
Matsumoto, T.12
Gunnett, K.13
Falcey, J.14
Waksal, H.15
Hong, W.K.16
-
47
-
-
0033966576
-
In vivo enhancement of tumor radioresponse by C225 antiepidermal growth factor receptor antibody
-
(2000)
Clinical Cancer Research
, vol.6
, pp. 701-706
-
-
Milas, L.1
Mason, K.2
Hunter, N.3
Petersen, S.4
Yamakawa, M.5
Ang, K.6
Mendelsohn, J.7
Fan, Z.8
-
48
-
-
8944263458
-
Phase I trial and tumour localisation of the anti-EGFR monoclonal antibody ICR62 in head and neck or lung cancer
-
(1996)
British Journal of Cancer
, vol.73
, pp. 228-235
-
-
Modjtahedi, H.1
Hickish, T.2
Nicolson, M.3
Moore, J.4
Styles, J.5
Eccles, S.6
Jackson, E.7
Salter, J.8
Sloane, J.9
Spencer, L.10
Priest, K.11
Smith, I.12
Dean, C.13
Gore, M.14
-
49
-
-
0030774045
-
Induction of apoptosis and cell cycle arrest by CP-358,774, an inhibitor of epidermal growth factor receptor tyrosine kinase
-
(1997)
Cancer Research
, vol.57
, pp. 4838-4848
-
-
Moyer, J.D.1
Barbacci, E.G.2
Iwata, K.K.3
Arnold, L.4
Boman, B.5
Cunningham, A.6
DiOrio, C.7
Doty, J.8
Morin, M.J.9
Moyer, M.P.10
Neveu, M.11
Pollack, V.A.12
Pustilnik, L.R.13
Reynolds, M.M.14
Sloan, D.15
Theleman, A.16
Miller, P.17
-
53
-
-
0028208423
-
Tumor epidermal growth factor receptor studies in patients with non-small cell lung cancer or head and neck cancer treated with monoclonal antibody RG 83852
-
(1994)
Journal of Clinical Oncology
, vol.12
, pp. 730-739
-
-
Perez-Soler, R.1
Donato, N.J.2
Shin, D.M.3
Rosenblum, M.G.4
Zhang, H.-Z.5
Tornos, C.6
Brewer, H.7
Chan, J.C.8
Lee, J.S.9
Hong, W.K.10
Murray, J.L.11
-
54
-
-
0001659382
-
Tumor studies in patients with head and neck cancer treated with humanized anti-epidermal growth factor (EGFR) monoclonal antibody C225 in combination with cisplatin
-
(1998)
Proceedings of the Annual Meeting of the American Society for Clinical Oncology
, vol.17
-
-
Perez-Soler, R.1
Shin, D.M.2
Donato, N.3
Radinsky, R.4
Khuri, F.5
Glisson, B.S.6
Shin, H.7
Matsumoto, T.8
Lawhorn, K.9
Waksal, H.10
Hong, W.K.11
Mendelsohn, J.12
-
55
-
-
0032972944
-
Anti-epidermal growth factor receptor antibody C225 inhibits angiogenesis in human transitional cell carcinoma growing orthotopically in nude mice
-
(1999)
Clinical Cancer Research
, vol.5
, pp. 257-265
-
-
Perrotte, P.1
Matsumoto, T.2
Inoue, K.3
Kuniyasu, H.4
Eve, B.Y.5
Hicklin, D.J.6
Radinsky, R.7
Dinney, C.P.8
-
60
-
-
0033587022
-
Tyrosine kinase inhibitors. 15. 4-(phenylamino)quinazoline and 4-(phenylamino)pyrido[d]pyrimidine acrylamides as irreversible inhibitors of the ATP binding site of the epidermal growth factor receptor
-
(1999)
Journal of Medicinal Chemistry
, vol.42
, pp. 1803-1815
-
-
Smaill, J.B.1
Palmer, B.D.2
Rewcastle, G.W.3
Denny, W.A.4
McNamara, D.J.5
Dobrusin, E.M.6
Bridges, A.J.7
Zhou, H.8
Showalter, H.D.9
Winters, R.T.10
Leopold, W.R.11
Fry, D.W.12
Nelson, J.M.13
Slintak, V.14
Elliot, W.L.15
Roberts, B.J.16
Vincent, P.W.17
Patmore, S.J.18
-
62
-
-
0032951396
-
Cooperative inhibitory effect of novel mixed backbone oligonucleotide targeting protein kinase A in combination with docetaxel and anti-epidermal growth factor-receptor antibody on human breast cancer cell growth
-
(1999)
Clinical Cancer Research
, vol.5
, pp. 875-881
-
-
Tortora, G.1
Caputo, R.2
Pomatico, G.3
Pepe, S.4
Bianco, A.R.5
Agrawal, S.6
Mendelsohn, J.7
Ciardiello, F.8
-
63
-
-
0021273420
-
Human epidermal growth factor receptor cRNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells
-
(1984)
Nature
, vol.309
, pp. 418-425
-
-
Ullrich, A.1
Coussens, L.2
Hayflick, J.S.3
Dull, T.J.4
Gray, A.5
Tam, A.W.6
Lee, J.7
Yarden, Y.8
Libermann, T.A.9
Schlessinger, J.10
-
66
-
-
0021154199
-
Human epidermal growth factor receptor cDNA is homologous to a variety of RNAs overproduced in A431 carcinoma cells
-
(1984)
Nature
, vol.309
, pp. 806-810
-
-
Xu, Y.H.1
Ishii, S.2
Clark, A.J.3
Sullivan, M.4
Wilson, R.K.5
Ma, D.P.6
Roe, B.A.7
Merlino, G.T.8
Pastan, I.9
|