-
1
-
-
84940295801
-
-
About Alzheimer Disease
-
About Alzheimer Disease. Bright Focus Foundation; 2012. www.ahaf.org/alzheimers
-
(2012)
Bright Focus Foundation
-
-
-
2
-
-
2342466734
-
Global prevalence of diabetes: Estimates for the year 2000 and projections for 2030
-
Wild S, Roglic G, Green A, Sicree R, King H. Global prevalence of diabetes: estimates for the year 2000 and projections for 2030. Diabetes Care 2004; 27: 1047-53.
-
(2004)
Diabetes Care
, vol.27
, pp. 1047-1053
-
-
Wild, S.1
Roglic, G.2
Green, A.3
Sicree, R.4
King, H.5
-
3
-
-
0041877634
-
Proteomics as a tool for discovery: Proteins implicated in Alzheimer's disease are highly expressed in normal pancreatic islets
-
Nicolls MRD, Antonio JM, Hutton JC, et al. Proteomics as a tool for discovery: Proteins implicated in Alzheimer's disease are highly expressed in normal pancreatic islets. J Proteome Res 2003; 2: 199-205.
-
(2003)
J Proteome Res
, vol.2
, pp. 199-205
-
-
Nicolls, M.R.D.1
Antonio, J.M.2
Hutton, J.C.3
-
4
-
-
1542752823
-
Does diabetes protect or provoke Alzheimer's disease? Insights into the pathobiology and future treatment of Alzheimer's disease
-
Grossman H. Does diabetes protect or provoke Alzheimer's disease? Insights into the pathobiology and future treatment of Alzheimer's disease. CNS Spectr 2003; 8(11): 815-23.
-
(2003)
CNS Spectr
, vol.8
, Issue.11
, pp. 815-823
-
-
Grossman, H.1
-
5
-
-
67349112388
-
Common features between diabetes mellitus and Alzheimer's disease
-
Götz J, Ittner LM, Lim Y. Common features between diabetes mellitus and Alzheimer's disease. Cell Mol Life Sci 2009; 66(8): 1321-5.
-
(2009)
Cell Mol Life Sci
, vol.66
, Issue.8
, pp. 1321-1325
-
-
Götz, J.1
Ittner, L.M.2
Lim, Y.3
-
6
-
-
0037390039
-
Insulin-degrading enzyme regulates the levels of insulin, amyloid beta-protein, and the beta-amyloid precursor protein intra-cellular domain in vivo
-
Farris W, Mansourian S, Chang Y, et al. Insulin-degrading enzyme regulates the levels of insulin, amyloid beta-protein, and the beta-amyloid precursor protein intra-cellular domain in vivo. Proc Natl Acad Sci USA 2003; 100: 4162-7.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 4162-4167
-
-
Farris, W.1
Mansourian, S.2
Chang, Y.3
-
7
-
-
0037947406
-
Amyloid-beta peptide levels in brain are inversely correlated with insulysin activity levels in vivo
-
Miller BC, Eckman EA, Sambamurti K, et al. Amyloid-beta peptide levels in brain are inversely correlated with insulysin activity levels in vivo. Proc Natl Acad Sci USA 2003; 100: 6221-6.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 6221-6226
-
-
Miller, B.C.1
Eckman, E.A.2
Sambamurti, K.3
-
8
-
-
1642290835
-
Partial loss-of-function mutations in insulin-degrading enzyme that induce diabetes also impair degradation of amyloid beta-protein
-
Farris W, Mansourian S, Leissring MA, et al. Partial loss-of-function mutations in insulin-degrading enzyme that induce diabetes also impair degradation of amyloid beta-protein. Am J Pathol 2004; 164: 1425-34.
-
(2004)
Am J Pathol
, vol.164
, pp. 1425-1434
-
-
Farris, W.1
Mansourian, S.2
Leissring, M.A.3
-
9
-
-
0035411025
-
A is for Amylin and Amyloid in Type 2 Diabetes Mellitus; JOP
-
Hayden MR, Tyagi SC. "A" is for Amylin and Amyloid in Type 2 Diabetes Mellitus; JOP. J Pancreas 2001; 2(4): 124-39.
-
(2001)
J Pancreas
, vol.2
, Issue.4
, pp. 124-139
-
-
Hayden, M.R.1
Tyagi, S.C.2
-
10
-
-
33644591150
-
Insulin and insulin-like growth factor expression and function deteriorate with progression of Alzheimer's disease: Link to brain reductions in acetylcholine
-
Rivera EJ, Goldin A, Fulmer N, et al. Insulin and insulin-like growth factor expression and function deteriorate with progression of Alzheimer's disease: link to brain reductions in acetylcholine. J Alzheimers Dis 2005; 8: 247-68.
-
(2005)
J Alzheimers Dis
, vol.8
, pp. 247-268
-
-
Rivera, E.J.1
Goldin, A.2
Fulmer, N.3
-
11
-
-
15244351255
-
Impaired insulin and insulin-like growth factor expression and signaling mechanisms in Alzheimer's disease -is this type 3 diabetes?
-
Steen E, Terry BM, Rivera EJ, et al. Impaired insulin and insulin-like growth factor expression and signaling mechanisms in Alzheimer's disease -is this type 3 diabetes? J Alzheimers Dis 2005; 7: 63-80.
-
(2005)
J Alzheimers Dis
, vol.7
, pp. 63-80
-
-
Steen, E.1
Terry, B.M.2
Rivera, E.J.3
-
12
-
-
25844491778
-
Plasma visfatin concentrations and fat depot-specific mRNA expression in humans
-
Berndt J, Kloting N, Kralisch S, et al. Plasma visfatin concentrations and fat depot-specific mRNA expression in humans. Diabetes 2005; 54: 2911-6.
-
(2005)
Diabetes
, vol.54
, pp. 2911-2916
-
-
Berndt, J.1
Kloting, N.2
Kralisch, S.3
-
13
-
-
13344295079
-
Serum immunoreactiveleptin concentrations in normal-weight and obese humans
-
Considine RV, Sinha MK, Heiman ML, et al. Serum immunoreactiveleptin concentrations in normal-weight and obese humans. N Eng J Med 1996; 334: 292-5.
-
(1996)
N Eng J Med
, vol.334
, pp. 292-295
-
-
Considine, R.V.1
Sinha, M.K.2
Heiman, M.L.3
-
14
-
-
0034096988
-
Plasma concentrations of a novel, adipose-specific protein, adiponectin, in type 2 diabetic patients
-
Hotta K, Funahashi T, Arita Y, et al. Plasma concentrations of a novel, adipose-specific protein, adiponectin, in type 2 diabetic patients. Arterioscler Thromb Vasc Biol 2000; 20: 1595-9.
-
(2000)
Arterioscler Thromb Vasc Biol
, vol.20
, pp. 1595-1599
-
-
Hotta, K.1
Funahashi, T.2
Arita, Y.3
-
15
-
-
33947725216
-
Plasma resistin levels correlate with determinants of the metabolic syndrome
-
Norata GD.; Ongari M, Garlaschelli K, et al. Plasma resistin levels correlate with determinants of the metabolic syndrome. Eur J Endocrinol 2007; 156: 279-84.
-
(2007)
Eur J Endocrinol
, vol.156
, pp. 279-284
-
-
Norata, G.D.1
Ongari, M.2
Garlaschelli, K.3
-
16
-
-
0035403205
-
Circulating interleukin-6 in relation to adiposity, insulin action, and insulin secretion
-
Vozarova B, Weyer C, Hanson K, et al. Circulating interleukin-6 in relation to adiposity, insulin action, and insulin secretion. Obes Res 2001; 9: 414-7.
-
(2001)
Obes Res
, vol.9
, pp. 414-417
-
-
Vozarova, B.1
Weyer, C.2
Hanson, K.3
-
17
-
-
0043237377
-
Protein disregulation in red blood cell membranes of type 2 diabetic patients
-
Jiang M, Jia L, Jiang W, et al. Protein disregulation in red blood cell membranes of type 2 diabetic patients. Biochem Biophys Res Commun 2003: 309: 196-200.
-
(2003)
Biochem Biophys Res Commun
, vol.309
, pp. 196-200
-
-
Jiang, M.1
Jia, L.2
Jiang, W.3
-
18
-
-
37849187930
-
Arginase-flotillin interaction brings arginase to red blood cell membrane
-
Jiang M, Ding Y, Su Y, et al. Arginase-flotillin interaction brings arginase to red blood cell membrane. FEBS Lett 2006; 580: 6561-4.
-
(2006)
FEBS Lett
, vol.580
, pp. 6561-6564
-
-
Jiang, M.1
Ding, Y.2
Su, Y.3
-
19
-
-
0942276226
-
Mining biomarkers in human sera using proteomic tools
-
Zhang R, Barker L, Pinchev D, et al. Mining biomarkers in human sera using proteomic tools. Proteomics 2004; 4: 244-56.
-
(2004)
Proteomics
, vol.4
, pp. 244-256
-
-
Zhang, R.1
Barker, L.2
Pinchev, D.3
-
20
-
-
27744503664
-
Plasma IL-6 concentration is inversely related to insulin sensitivity, and acute-phase proteins associate with glucose and lipid metabolism in healthy subjects
-
Heliovaara MK, Teppo AM, Karonen SL, et al. Plasma IL-6 concentration is inversely related to insulin sensitivity, and acute-phase proteins associate with glucose and lipid metabolism in healthy subjects. Diabetes Obes Metab 2005; 7: 729-36.
-
(2005)
Diabetes Obes Metab
, vol.7
, pp. 729-736
-
-
Heliovaara, M.K.1
Teppo, A.M.2
Karonen, S.L.3
-
21
-
-
0036230414
-
Elevated levels of acutephase proteins and plasminogen activator inhibitor-1 predict the development of type 2 diabetes: The insulin resistance atherosclerosis study
-
Festa A, D'Agostino Jr R, Tracy RP, Haffner SM. Elevated levels of acutephase proteins and plasminogen activator inhibitor-1 predict the development of type 2 diabetes: the insulin resistance atherosclerosis study. Diabetes 2002; 51: 1131-7.
-
(2002)
Diabetes
, vol.51
, pp. 1131-1137
-
-
Festa, A.1
D'Agostino, R.2
Tracy, R.P.3
Haffner, S.M.4
-
22
-
-
41949110827
-
Plasma proteome changes in type 2 diabetes mellitus subjects with low or high early insulin response
-
Sundsten T, Zethelius B, Berne C, Bergsten P. Plasma proteome changes in type 2 diabetes mellitus subjects with low or high early insulin response. Clin Sci (Lond) 2008a; 114: 499-507.
-
(2008)
Clin Sci (Lond)
, vol.114
, pp. 499-507
-
-
Sundsten, T.1
Zethelius, B.2
Berne, C.3
Bergsten, P.4
-
23
-
-
3042789100
-
Apolipoprotein CIII promotes Ca2+-dependent beta cell death in type 1 diabetes
-
Juntti-Berggren L, Refai E, Appelskog I, et al. Apolipoprotein CIII promotes Ca2+-dependent beta cell death in type 1 diabetes. Proc Natl Acad Sci USA 2004; 101: 10090-4.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 10090-10094
-
-
Juntti-Berggren, L.1
Refai, E.2
Appelskog, I.3
-
24
-
-
0034097892
-
Triglycerides, apo C3 and Lp B: C3 and cardiovascular risk in type II diabetes
-
Gervaise N, Garrigue MA, Lasfargues G, Lecomte P. Triglycerides, apo C3 and Lp B: C3 and cardiovascular risk in type II diabetes. Diabetologia 2000; 43: 703-8.
-
(2000)
Diabetologia
, vol.43
, pp. 703-708
-
-
Gervaise, N.1
Garrigue, M.A.2
Lasfargues, G.3
Lecomte, P.4
-
25
-
-
33749612183
-
Effect of fungal polysaccharides on the modulation of plasma proteins in streptozotocin-induced diabetic rats
-
Kim SW, Hwang HJ, Kim HM, et al. Effect of fungal polysaccharides on the modulation of plasma proteins in streptozotocin-induced diabetic rats. Proteomics 2006; 6: 5291-302.
-
(2006)
Proteomics
, vol.6
, pp. 5291-5302
-
-
Kim, S.W.1
Hwang, H.J.2
Kim, H.M.3
-
26
-
-
0026651186
-
Transthyretin (prealbumin) in the pancreas and sera of newly diagnosed type I (insulin-dependent) diabetic patients
-
Itoh N, Hanafusa T, Miyagawa J, et al. Transthyretin (prealbumin) in the pancreas and sera of newly diagnosed type I (insulin-dependent) diabetic patients. J Clin Endocrinol Metab 1992; 74: 1372-7.
-
(1992)
J Clin Endocrinol Metab
, vol.74
, pp. 1372-1377
-
-
Itoh, N.1
Hanafusa, T.2
Miyagawa, J.3
-
27
-
-
33947609131
-
Clinical indications for plasma protein assays: Transthyretin (prealbumin) in inflammation and malnutrition
-
Myron Johnson A, Merlini G, Sheldon J, Ichihara K. Clinical indications for plasma protein assays: transthyretin (prealbumin) in inflammation and malnutrition. Clin Chem Lab Med 2007; 45: 419-26.
-
(2007)
Clin Chem Lab Med
, vol.45
, pp. 419-426
-
-
Myron, J.A.1
Merlini, G.2
Sheldon, J.3
Ichihara, K.4
-
28
-
-
1442275317
-
Inflammation and activated innate immunity in the pathogenesis of type 2 diabetes
-
Pickup JC. Inflammation and activated innate immunity in the pathogenesis of type 2 diabetes. Diabetes Care 2004; 27: 813-23.
-
(2004)
Diabetes Care
, vol.27
, pp. 813-823
-
-
Pickup, J.C.1
-
29
-
-
31544441352
-
Inflammation and the etiology of type 2 diabetes
-
Sjoholm A, Nystrom T. Inflammation and the etiology of type 2 diabetes. Diabetes Metab Res Rev 2006; 22: 4-10.
-
(2006)
Diabetes Metab Res Rev
, vol.22
, pp. 4-10
-
-
Sjoholm, A.1
Nystrom, T.2
-
30
-
-
0033545342
-
Acute-phase proteins and other systemic responses to inflammation
-
Gabay C, Kushner I. Acute-phase proteins and other systemic responses to inflammation. N Engl J Med 1999; 340: 448-54.
-
(1999)
N Engl J Med
, vol.340
, pp. 448-454
-
-
Gabay, C.1
Kushner, I.2
-
31
-
-
0025724030
-
Nucleotide sequence and expression of the human gene encoding apolipoprotein H (beta 2-glycoprotein I)
-
Mehdi H, Nunn M, Steel DM, et al. Nucleotide sequence and expression of the human gene encoding apolipoprotein H (beta 2-glycoprotein I). Gene 1991; 108: 293-8.
-
(1991)
Gene
, vol.108
, pp. 293-298
-
-
Mehdi, H.1
Nunn, M.2
Steel, D.M.3
-
32
-
-
0033922568
-
Protein nutritional status and function are associated with type 2 diabetes in Hispanic elders
-
Castaneda C, Bermudez OI, Tucker KL. Protein nutritional status and function are associated with type 2 diabetes in Hispanic elders. Am J Clin Nutr 2000; 72: 89-95.
-
(2000)
Am J Clin Nutr
, vol.72
, pp. 89-95
-
-
Castaneda, C.1
Bermudez, O.I.2
Tucker, K.L.3
-
33
-
-
33644874405
-
Increased urinary excretions of immunoglobulin g, ceruloplasmin, and transferrin predict development of microalbuminuria in patients with type 2 diabetes
-
Narita T, Hosoba M, Kakei M, Ito S. Increased urinary excretions of immunoglobulin g, ceruloplasmin, and transferrin predict development of microalbuminuria in patients with type 2 diabetes. Diabetes Care 2006; 29: 142-4.
-
(2006)
Diabetes Care
, vol.29
, pp. 142-144
-
-
Narita, T.1
Hosoba, M.2
Kakei, M.3
Ito, S.4
-
34
-
-
33748082985
-
Differential expression of proteins in kidney, eye, aorta, and serum of diabetic and non-diabetic rats
-
Cho WC, Yip TT, Chung WS, et al. Differential expression of proteins in kidney, eye, aorta, and serum of diabetic and non-diabetic rats. J Cell Biochem 2006; 99: 256-68.
-
(2006)
J Cell Biochem
, vol.99
, pp. 256-268
-
-
Cho, W.C.1
Yip, T.T.2
Chung, W.S.3
-
35
-
-
0035908632
-
C-reactive protein, interleukin 6: And risk of developing type 2 diabetes mellitus
-
Pradhan AD, Manson JE, Rifai N, et al. C-reactive protein, interleukin 6: and risk of developing type 2 diabetes mellitus. JAMA 2001; 286: 327-34.
-
(2001)
JAMA
, vol.286
, pp. 327-334
-
-
Pradhan, A.D.1
Manson, J.E.2
Rifai, N.3
-
37
-
-
12944291304
-
Effect of green tea on blood glucose levels and serum proteomic patterns in diabetic (db/db) mice and on glucose metabolism in healthy humans
-
Tsuneki H, Ishizuka M, Terasawa M, et al. Effect of green tea on blood glucose levels and serum proteomic patterns in diabetic (db/db) mice and on glucose metabolism in healthy humans. BMC Pharmacol 2004; 4: 18.
-
(2004)
BMC Pharmacol
, vol.4
, pp. 18
-
-
Tsuneki, H.1
Ishizuka, M.2
Terasawa, M.3
-
38
-
-
21144457088
-
Expression patterns of plasma proteins in spontaneously diabetic rats after oral administration of a Kampo medicine, Hachimi-jio-gan, using SELDI ProteinChip platform
-
Kiga C, Nakagawa T, Koizumi K, et al. Expression patterns of plasma proteins in spontaneously diabetic rats after oral administration of a Kampo medicine, Hachimi-jio-gan, using SELDI ProteinChip platform. Biol Pharm Bull 2005; 28: 1031-7.
-
(2005)
Biol Pharm Bull
, vol.28
, pp. 1031-1037
-
-
Kiga, C.1
Nakagawa, T.2
Koizumi, K.3
-
39
-
-
67650070809
-
Development of a type 2 diabetes risk model from a panel of serum biomarkers from the Inter99cohort
-
Kolberg JA, Jorgensen T, Gerwien RW, et al. Development of a type 2 diabetes risk model from a panel of serum biomarkers from the Inter99cohort. Diabetes Care 2009; 32: 1207-12.
-
(2009)
Diabetes Care
, vol.32
, pp. 1207-1212
-
-
Kolberg, J.A.1
Jorgensen, T.2
Gerwien, R.W.3
-
40
-
-
77956336714
-
Thirty-one novel biomarkers as predictors for clinically incident diabetes
-
Salomaa V, Havulinna A, Saarela O, et al. Thirty-one novel biomarkers as predictors for clinically incident diabetes. PLoS One 2010; 5(4): e10100.
-
(2010)
PLoS One
, vol.5
, Issue.4
-
-
Salomaa, V.1
Havulinna, A.2
Saarela, O.3
-
41
-
-
80053549390
-
Joint analysis of multiple biomarkers for identifying type 2 diabetes in middle-aged and older Chinese: A crosssectional study
-
Wu H, Yu Z, Qi Q, et al. Joint analysis of multiple biomarkers for identifying type 2 diabetes in middle-aged and older Chinese: A crosssectional study. Br Med J 2011; 1: e000191.
-
(2011)
Br Med J
, vol.1
-
-
Wu, H.1
Yu, Z.2
Qi, Q.3
-
42
-
-
2942644152
-
Levels of ceruloplasmin, transferrin, and lipid peroxidation in the serum of patients with Type 2 diabetes mellitus
-
Memisogullari R, Bakan E. Levels of ceruloplasmin, transferrin, and lipid peroxidation in the serum of patients with Type 2 diabetes mellitus. J Diabetes Compl 2004; 18: 193-7.
-
(2004)
J Diabetes Compl
, vol.18
, pp. 193-197
-
-
Memisogullari, R.1
Bakan, E.2
-
43
-
-
33846018940
-
The use of proteomics in identifying differentially expressed serum proteins in humans with type 2 diabetes
-
Sundsten T, Eberhardson M, Goransson M, Bergsten P. The use of proteomics in identifying differentially expressed serum proteins in humans with type 2 diabetes. Proteome Sci 2006; 4: 22.
-
(2006)
Proteome Sci
, vol.4
, pp. 22
-
-
Sundsten, T.1
Eberhardson, M.2
Goransson, M.3
Bergsten, P.4
-
44
-
-
39649099152
-
Serum protein patterns in newly diagnosed type 2 diabetes mellitus -Influence of diabetic environment and family history of diabetes
-
Sundsten T, Ostenson CG, Bergsten P. Serum protein patterns in newly diagnosed type 2 diabetes mellitus -Influence of diabetic environment and family history of diabetes. Diabetes Metab Res Rev 2008a; 24: 148-54.
-
(2008)
Diabetes Metab Res Rev
, vol.24
, pp. 148-154
-
-
Sundsten, T.1
Ostenson, C.G.2
Bergsten, P.3
-
45
-
-
72749088422
-
Proteomic identification of human serum biomarkers in diabetes mellitus type 2
-
Riaz S, Alam SS, Akhtar MW. Proteomic identification of human serum biomarkers in diabetes mellitus type 2. J Pharm Biomed Anal 2010a; 51: 1103-7.
-
(2010)
J Pharm Biomed Anal
, vol.51
, pp. 1103-1107
-
-
Riaz, S.1
Alam, S.S.2
Akhtar, M.W.3
-
46
-
-
52449124453
-
Localized-statistical quantification of human serum proteome associated with type 2 diabetes
-
Li RX, Chen HB, Tu K, et al. Localized-statistical quantification of human serum proteome associated with type 2 diabetes. PLoS One 2008; 3: e3224.
-
(2008)
PLoS One
, vol.3
-
-
Li, R.X.1
Chen, H.B.2
Tu, K.3
-
47
-
-
1542313783
-
Core biological marker candidates of Alzheimer's disease-perspectives for diagnosis, prediction of outcome and reflection of biological activity
-
Hampel H, Mitchell A, Blennow K, et al. Core biological marker candidates of Alzheimer's disease-perspectives for diagnosis, prediction of outcome and reflection of biological activity. J Neural Transm 2004; 111: 247-72.
-
(2004)
J Neural Transm
, vol.111
, pp. 247-272
-
-
Hampel, H.1
Mitchell, A.2
Blennow, K.3
-
48
-
-
0026776587
-
Abnormal expression of actin in lymphocytes of Alzheimer's disease and Down's syndrome patients
-
Jabbour W, Pouplard-Barthelaix A, Houlgatte R, et al. Abnormal expression of actin in lymphocytes of Alzheimer's disease and Down's syndrome patients. J Neuroimmunol 1992; 38: 199-208.
-
(1992)
J Neuroimmunol
, vol.38
, pp. 199-208
-
-
Jabbour, W.1
Pouplard-Barthelaix, A.2
Houlgatte, R.3
-
49
-
-
0029175962
-
Two-dimensional analysis of qualitative and quantitative changes in blood cell proteins in Alzheimer's disease: Search for extraneuronal markers
-
Mattila KM, Frey H. Two-dimensional analysis of qualitative and quantitative changes in blood cell proteins in Alzheimer's disease: search for extraneuronal markers. Appl Theor Electrophor 1995; 4: 189-96.
-
(1995)
Appl Theor Electrophor
, vol.4
, pp. 189-196
-
-
Mattila, K.M.1
Frey, H.2
-
50
-
-
0022462178
-
Isoelectric focusing and two-dimensional gel electrophoresis in plasma and cerebrospinal fluid from patients with dementia
-
Alafuzoff I, Adolfsson R, Bucht G, et al. Isoelectric focusing and two-dimensional gel electrophoresis in plasma and cerebrospinal fluid from patients with dementia. Eur Neurol 1986; 25: 285-9.
-
(1986)
Eur Neurol
, vol.25
, pp. 285-289
-
-
Alafuzoff, I.1
Adolfsson, R.2
Bucht, G.3
-
52
-
-
0034120636
-
Analysis of blood plasma proteins in patients with Alzheimer's disease by two-dimensional electrophoresis, sequence homology and immunodetection
-
Ueno I, Sakai T, Yamaoka M, et al. Analysis of blood plasma proteins in patients with Alzheimer's disease by two-dimensional electrophoresis, sequence homology and immunodetection. Electrophoresis 2000; 21: 1832-45.
-
(2000)
Electrophoresis
, vol.21
, pp. 1832-1845
-
-
Ueno, I.1
Sakai, T.2
Yamaoka, M.3
-
53
-
-
0942276226
-
Mining biomarkers in human sera using proteomic tools
-
Zhang R, Barker L, Pinchev D, et al. Mining biomarkers in human sera using proteomic tools. Proteomics 2004; 4: 244-56.
-
(2004)
Proteomics
, vol.4
, pp. 244-256
-
-
Zhang, R.1
Barker, L.2
Pinchev, D.3
-
54
-
-
17244367596
-
Proteome analysis in the clinical chemistry laboratory: Myth or reality?
-
Righetti PG, Castagna A, Antonucci F, et al. Proteome analysis in the clinical chemistry laboratory: myth or reality? Clin Chim Acta 2005; 357: 123-39.
-
(2005)
Clin Chim Acta
, vol.357
, pp. 123-139
-
-
Righetti, P.G.1
Castagna, A.2
Antonucci, F.3
-
55
-
-
43449137299
-
Protein biomarkers for amyotrophic lateral sclerosis
-
Ryberg H, Bowser R. Protein biomarkers for amyotrophic lateral sclerosis. Expert Rev Proteomics 2008; 5: 249-62.
-
(2008)
Expert Rev Proteomics
, vol.5
, pp. 249-262
-
-
Ryberg, H.1
Bowser, R.2
-
56
-
-
39649110895
-
Blood-based proteomics for personalized medicine: Examples from neurodegenerative disease
-
Goldknopf IL. Blood-based proteomics for personalized medicine: examples from neurodegenerative disease. Expert Rev Proteomics 2008; 5: 1-8.
-
(2008)
Expert Rev Proteomics
, vol.5
, pp. 1-8
-
-
Goldknopf, I.L.1
-
57
-
-
33750596715
-
Proteome-based plasma biomarkers for Alzheimer's disease
-
Hye A, Lynham S, Thambisetty M, et al. Proteome-based plasma biomarkers for Alzheimer's disease. Brain 2006; 129: 3042-50.
-
(2006)
Brain
, vol.129
, pp. 3042-3050
-
-
Hye, A.1
Lynham, S.2
Thambisetty, M.3
-
58
-
-
58549087156
-
Proteome-based identification of plasma proteins associated with hippocampal metabolism in early Alzheimer's disease
-
Thambisetty M, Hye A, Foy C, et al. Proteome-based identification of plasma proteins associated with hippocampal metabolism in early Alzheimer's disease. J Neurol 2008; 255: 1712-20.
-
(2008)
J Neurol
, vol.255
, pp. 1712-1720
-
-
Thambisetty, M.1
Hye, A.2
Foy, C.3
-
59
-
-
32044446447
-
Proteomic identification of lower apolipoprotein A-I in Alzheimer's disease
-
Liu HC, Hu CJ, Chang JG, et al. Proteomic identification of lower apolipoprotein A-I in Alzheimer's disease. Dement Geriatr Cogn Disord 2006; 21: 155-61.
-
(2006)
Dement Geriatr Cogn Disord
, vol.21
, pp. 155-161
-
-
Liu, H.C.1
Hu, C.J.2
Chang, J.G.3
-
60
-
-
70449348828
-
Proteomics-derived cerebrospinal fluid markers of autopsy-confirmed Alzheimer's disease
-
Roher AE, Maarouf CL, Sue LI, et al. Proteomics-derived cerebrospinal fluid markers of autopsy-confirmed Alzheimer's disease. Biomarkers 2009; 14(7): 493-501.
-
(2009)
Biomarkers
, vol.14
, Issue.7
, pp. 493-501
-
-
Roher, A.E.1
Maarouf, C.L.2
Sue, L.I.3
-
61
-
-
70349499185
-
Plasma biomarkers for mild cognitive impairment and Alzheimer's disease
-
Song F, Poljak A, Smythe GA, et al. Plasma biomarkers for mild cognitive impairment and Alzheimer's disease. Brain Res Rev 2009; 61: 69-80.
-
(2009)
Brain Res Rev
, vol.61
, pp. 69-80
-
-
Song, F.1
Poljak, A.2
Smythe, G.A.3
-
62
-
-
0041829098
-
Expression of melanotransferrin isoforms in human serum: Relevance to Alzheimer's disease
-
Desrosiers RR, Bertrand Y, Nguyen QT, et al. Expression of melanotransferrin isoforms in human serum: relevance to Alzheimer's disease. Biochem J 2003; 374: 463-71.
-
(2003)
Biochem J
, vol.374
, pp. 463-471
-
-
Desrosiers, R.R.1
Bertrand, Y.2
Nguyen, Q.T.3
-
63
-
-
0242440004
-
Aberrant profiles of native and oxidized glycoproteins in Alzheimer plasma
-
Yu HL, Chertkow HM, Bergman H, et al. Aberrant profiles of native and oxidized glycoproteins in Alzheimer plasma. Proteomics 2003; 3: 2240-8.
-
(2003)
Proteomics
, vol.3
, pp. 2240-2248
-
-
Yu, H.L.1
Chertkow, H.M.2
Bergman, H.3
-
64
-
-
0036079419
-
Identification of oxidized plasma proteins in Alzheimer's disease
-
Choi J, Malakowsky CA, Talent JM, et al. Identification of oxidized plasma proteins in Alzheimer's disease. Biochem Biophys Res Commun 2002; 293: 1566-70.
-
(2002)
Biochem Biophys Res Commun
, vol.293
, pp. 1566-1570
-
-
Choi, J.1
Malakowsky, C.A.2
Talent, J.M.3
-
65
-
-
51449086260
-
Proteomic analysis of peripheral leukocytes in Alzheimer's disease patients treated with divalproex sodium
-
Mhyre TR, Loy R, Tariot PN, et al. Proteomic analysis of peripheral leukocytes in Alzheimer's disease patients treated with divalproex sodium. Neurobiol Aging 2008; 29: 1631-43.
-
(2008)
Neurobiol Aging
, vol.29
, pp. 1631-1643
-
-
Mhyre, T.R.1
Loy, R.2
Tariot, P.N.3
-
66
-
-
33748463935
-
Causes and diagnosis of Alzheimer's disease: A proteomics approach
-
Poljak A, Sachdev P, Smythe GA. Causes and diagnosis of Alzheimer's disease: a proteomics approach. Proteomics 2006; 81-112.
-
(2006)
Proteomics
, pp. 81-112
-
-
Poljak, A.1
Sachdev, P.2
Smythe, G.A.3
-
67
-
-
36048982129
-
Conversion from cognitive health to mild cognitive impairment and Alzheimer's disease: Prediction by plasma amyloid beta 42: Medial temporal lobe atrophy and homocysteine
-
Blasko I, Jellinger K, Kemmler G, et al. Conversion from cognitive health to mild cognitive impairment and Alzheimer's disease: prediction by plasma amyloid beta 42: medial temporal lobe atrophy and homocysteine. Neurobiol Aging 2008; 29: 1-11.
-
(2008)
Neurobiol Aging
, vol.29
, pp. 1-11
-
-
Blasko, I.1
Jellinger, K.2
Kemmler, G.3
-
68
-
-
33947282076
-
Association of low plasma Abeta42/Abeta40 ratios with increased imminent risk for mild cognitive impairment and Alzheimer disease
-
Graff-Radford NR, Crook JE, Lucas J, et al. Association of low plasma Abeta42/Abeta40 ratios with increased imminent risk for mild cognitive impairment and Alzheimer disease. Arch Neurol 2007; 64: 354-62.
-
(2007)
Arch Neurol
, vol.64
, pp. 354-362
-
-
Graff-Radford, N.R.1
Crook, J.E.2
Lucas, J.3
-
69
-
-
34247384609
-
Prediction of Alzheimer's disease using the CSF Abeta42/Abeta40 ratio in patients with mild cognitive impairment
-
Hansson O, Zetterberg H, Buchhave P, et al. Prediction of Alzheimer's disease using the CSF Abeta42/Abeta40 ratio in patients with mild cognitive impairment. Dement Geriatr Cogn Disord 2007; 23: 316-20.
-
(2007)
Dement Geriatr Cogn Disord
, vol.23
, pp. 316-320
-
-
Hansson, O.1
Zetterberg, H.2
Buchhave, P.3
-
70
-
-
45149096784
-
Plasma amyloid beta-protein and C-reactive protein in relation to the rate of progression of Alzheimer disease
-
Locascio JJ, Fukumoto H, Yap L, et al. Plasma amyloid beta-protein and C-reactive protein in relation to the rate of progression of Alzheimer disease. Arc Neurol 2008; 65: 776-85.
-
(2008)
Arc Neurol
, vol.65
, pp. 776-785
-
-
Locascio, J.J.1
Fukumoto, H.2
Yap, L.3
-
71
-
-
0242412140
-
Plasma A+AFs-beta+AF0-40 and A+AFs-beta+AF0-42 and Alzheimer's disease: Relation to age, mortality, and risk
-
Mayeux R, Honig LS, Tang MX, et al. Plasma A+AFs-beta+AF0-40 and A+AFs-beta+AF0-42 and Alzheimer's disease: relation to age, mortality, and risk. Neurology 2003; 61: 1185-90.
-
(2003)
Neurology
, vol.61
, pp. 1185-1190
-
-
Mayeux, R.1
Honig, L.S.2
Tang, M.X.3
-
72
-
-
33644877175
-
Selective reductions in plasma A beta 1-42 in healthy elderly subjects during longitudinal follow-up: A preliminary report
-
Pomara N, Willoughby LM, Sidtis JJ, Mehta PD. Selective reductions in plasma A beta 1-42 in healthy elderly subjects during longitudinal follow-up: a preliminary report. Am J Geriatr Psychiatry 2005; 13: 914-7.
-
(2005)
Am J Geriatr Psychiatry
, vol.13
, pp. 914-917
-
-
Pomara, N.1
Willoughby, L.M.2
Sidtis, J.J.3
Mehta, P.D.4
-
73
-
-
33745959062
-
Plasma Abeta(1-40) and Abeta(1-42) and the risk of dementia: A prospective case-cohort study
-
Van Oijen M, Hofman A, Soares HD, Koudstaal PJ, Breteler MM. Plasma Abeta(1-40) and Abeta(1-42) and the risk of dementia: a prospective case-cohort study. Lancet Neurol 2006; 5: 655-60.
-
(2006)
Lancet Neurol
, vol.5
, pp. 655-660
-
-
van Oijen, M.1
Hofman, A.2
Soares, H.D.3
Koudstaal, P.J.4
Breteler, M.M.5
-
74
-
-
0037155581
-
Brain to plasma amyloid-beta efflux: A measure of brain amyloid burden in a mouse model of Alzheimer's disease
-
DeMattos RB, Bales KR, Cummins DJ, Paul SM, Holtzman DM. Brain to plasma amyloid-beta efflux: a measure of brain amyloid burden in a mouse model of Alzheimer's disease. Science 2002; 295: 2264-7.
-
(2002)
Science
, vol.295
, pp. 2264-2267
-
-
Demattos, R.B.1
Bales, K.R.2
Cummins, D.J.3
Paul, S.M.4
Holtzman, D.M.5
-
75
-
-
0033536163
-
Immunization with amyloid β attenuates Alzheimer-disease-like pathology in the PDAPP mouse
-
Schenk D, Barbour R, Dunn W, et al. Immunization with amyloid β attenuates Alzheimer-disease-like pathology in the PDAPP mouse. Nature 1999; 400: 173-7.
-
(1999)
Nature
, vol.400
, pp. 173-177
-
-
Schenk, D.1
Barbour, R.2
Dunn, W.3
-
76
-
-
0033835996
-
Peripherally administered antibodies against amyloid beta peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease
-
Bard F, Cannon C, Barbour R, et al. Peripherally administered antibodies against amyloid beta peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease. Nat Med 2000; 6: 916-9.
-
(2000)
Nat Med
, vol.6
, pp. 916-919
-
-
Bard, F.1
Cannon, C.2
Barbour, R.3
-
77
-
-
0037393454
-
Neuropathology of human Alzheimer disease after immunization with amyloid-β peptide: A case report
-
Nicoll JA, Wilkinson D, Holmesm C, et al. Neuropathology of human Alzheimer disease after immunization with amyloid-β peptide: a case report. Nat Med 2003; 9: 448-52.
-
(2003)
Nat Med
, vol.9
, pp. 448-452
-
-
Nicoll, J.A.1
Wilkinson, D.2
Holmesm, C.3
-
78
-
-
0036853548
-
Generation of antibodies specific for β amyloid by vaccination of patients with Alzheimer disease
-
Hock C, Konietzko U, Papassotiropoulos A, et al. Generation of antibodies specific for β amyloid by vaccination of patients with Alzheimer disease. Nat Med 2002; 8: 1270-5.
-
(2002)
Nat Med
, vol.8
, pp. 1270-1275
-
-
Hock, C.1
Konietzko, U.2
Papassotiropoulos, A.3
-
79
-
-
0038100154
-
Antibodies against β amyloid slow cognitive decline in Alzheimer's disease
-
Hock C, Konietzko U, Streffer JR, et al. Antibodies against β amyloid slow cognitive decline in Alzheimer's disease. Neuron 2003; 38: 547-54.
-
(2003)
Neuron
, vol.38
, pp. 547-554
-
-
Hock, C.1
Konietzko, U.2
Streffer, J.R.3
-
80
-
-
10744230547
-
Subacute meningoencephalitis in a subset of patients with AD after Aβ42 immunization
-
Orgogozo JM, Gilman S, Dartigues JF, et al. Subacute meningoencephalitis in a subset of patients with AD after Aβ42 immunization. Neurology 2003; 61: 46-54.
-
(2003)
Neurology
, vol.61
, pp. 46-54
-
-
Orgogozo, J.M.1
Gilman, S.2
Dartigues, J.F.3
-
81
-
-
31044443590
-
Circulating biomarkers of cognitive decline and dementia
-
Solfrizzi V, D'Introno A, Colacicco AM, et al. Circulating biomarkers of cognitive decline and dementia. Clin Chim Acta 2006; 364: 91-112.
-
(2006)
Clin Chim Acta
, vol.364
, pp. 91-112
-
-
Solfrizzi, V.1
D'Introno, A.2
Colacicco, A.M.3
-
82
-
-
13644249114
-
Peripheral biomarkers of oxidative damage in Alzheimer's disease: The road ahead
-
Pratico D. Peripheral biomarkers of oxidative damage in Alzheimer's disease: the road ahead. Neurobiol Aging 2005; 26: 581-3.
-
(2005)
Neurobiol Aging
, vol.26
, pp. 581-583
-
-
Pratico, D.1
-
83
-
-
0034302893
-
Isoprostanes, novel markers of oxidative injury, help understanding the pathogenesis of neurodegenerative diseases
-
Greco A, Minghetti L, Levi G. Isoprostanes, novel markers of oxidative injury, help understanding the pathogenesis of neurodegenerative diseases. Neurochem Res 2000; 25: 1357-64.
-
(2000)
Neurochem Res
, vol.25
, pp. 1357-1364
-
-
Greco, A.1
Minghetti, L.2
Levi, G.3
-
84
-
-
0032238783
-
Increased F2-isoprostanes in Alzheimer's disease: Evidence for enhanced lipid peroxidation in vivo
-
Pratico D, Lee VMY, Trojanowski JQ, Rokach J, Fitzgerald GA. Increased F2-isoprostanes in Alzheimer's disease: evidence for enhanced lipid peroxidation in vivo. FASEB J 1998; 12: 1777-83.
-
(1998)
FASEB J
, vol.12
, pp. 1777-1783
-
-
Pratico, D.1
Lee, V.M.Y.2
Trojanowski, J.Q.3
Rokach, J.4
Fitzgerald, G.A.5
-
85
-
-
0032588611
-
Increased CSF F2-isoprostane concentration in probable AD
-
Montine TJ, Beal MF, Cudkowicz ME, et al. Increased CSF F2-isoprostane concentration in probable AD. Neurology; 1999: 52: 562-5.
-
(1999)
Neurology
, vol.52
, pp. 562-565
-
-
Montine, T.J.1
Beal, M.F.2
Cudkowicz, M.E.3
-
86
-
-
0033762711
-
Increased 8: 12-iso-iPF2alpha-VI in Alzheimer's disease: Correlation of a noninvasive index of lipid peroxidation with disease severity
-
Pratico D, Clark CM, Lee VM, et al. Increased 8: 12-iso-iPF2alpha-VI in Alzheimer's disease: correlation of a noninvasive index of lipid peroxidation with disease severity. Ann Neurol 2000; 48: 809-12.
-
(2000)
Ann Neurol
, vol.48
, pp. 809-812
-
-
Pratico, D.1
Clark, C.M.2
Lee, V.M.3
-
87
-
-
0036284936
-
Increase of brain oxidative stress in mild cognitive impairment: A possible predictor of Alzheimer disease
-
Pratico D, Clark CM, Liun F, et al. Increase of brain oxidative stress in mild cognitive impairment: a possible predictor of Alzheimer disease. Arch Neurol 2002; 59: 972-6.
-
(2002)
Arch Neurol
, vol.59
, pp. 972-976
-
-
Pratico, D.1
Clark, C.M.2
Liun, F.3
-
88
-
-
0035984342
-
Peripheral F2-isoprostanes and F4-neuroprostanes are not increased in Alzheimer's disease
-
Montine TJ, Quinn JF, Milatovic D, et al. Peripheral F2-isoprostanes and F4-neuroprostanes are not increased in Alzheimer's disease. Ann Neurol 2002; 52: 175-9.
-
(2002)
Ann Neurol
, vol.52
, pp. 175-179
-
-
Montine, T.J.1
Quinn, J.F.2
Milatovic, D.3
-
89
-
-
0037180823
-
Inflammation and therapeutic vaccination in CNS diseases
-
Weiner HL, Selkoe DJ. Inflammation and therapeutic vaccination in CNS diseases. Nature 2002; 420: 879-84.
-
(2002)
Nature
, vol.420
, pp. 879-884
-
-
Weiner, H.L.1
Selkoe, D.J.2
-
90
-
-
0036250622
-
Biochemical markers related to Alzheimer's dementia in serum and cerebrospinal fluid
-
Teunissen CE, de Vente J, Steinbusch HW, De Bruijn C. Biochemical markers related to Alzheimer's dementia in serum and cerebrospinal fluid. Neurobiol Aging 2002; 23: 485-508.
-
(2002)
Neurobiol Aging
, vol.23
, pp. 485-508
-
-
Teunissen, C.E.1
de Vente, J.2
Steinbusch, H.W.3
de Bruijn, C.4
-
91
-
-
0033966340
-
Increased plasma levels of interleukin-1: Interleukin-6 and α -1-antichymotrypsin in patients with Alzheimer's disease: Peripheral inflammation or signals from the brain?
-
Licastro F, Pedrini S, Caputo L, et al. Increased plasma levels of interleukin-1: interleukin-6 and α -1-antichymotrypsin in patients with Alzheimer's disease: peripheral inflammation or signals from the brain? J Neuroimmunol 2000; 103: 97-102.
-
(2000)
J Neuroimmunol
, vol.103
, pp. 97-102
-
-
Licastro, F.1
Pedrini, S.2
Caputo, L.3
-
92
-
-
0030775197
-
Circulating cytokines in Alzheimer's disease
-
Singh VK, Guthikonda P. Circulating cytokines in Alzheimer's disease. J Psychiatr Res 1997; 31: 657-60.
-
(1997)
J Psychiatr Res
, vol.31
, pp. 657-660
-
-
Singh, V.K.1
Guthikonda, P.2
-
93
-
-
0032868874
-
Intracerebral production of tumor necrosis factor-α a local neuroprotective agent, in Alzheimer disease and vascular dementia
-
Tarkowski E, Blennow K, Wallin A, Tarkowski A. Intracerebral production of tumor necrosis factor-α a local neuroprotective agent, in Alzheimer disease and vascular dementia. J Clin Immunol 1999; 19: 223-30.
-
(1999)
J Clin Immunol
, vol.19
, pp. 223-230
-
-
Tarkowski, E.1
Blennow, K.2
Wallin, A.3
Tarkowski, A.4
-
94
-
-
0032774318
-
Inflammatory markers in younger vs elderly normal volunteers and in patients with Alzheimer's disease
-
Maes M, DeVos N, Wauters A, et al. Inflammatory markers in younger vs elderly normal volunteers and in patients with Alzheimer's disease. J Psychiatr Res 1999; 33: 397-405.
-
(1999)
J Psychiatr Res
, vol.33
, pp. 397-405
-
-
Maes, M.1
Devos, N.2
Wauters, A.3
-
95
-
-
0030855888
-
Serum interleukin-6 levels correlate with the severity of dementia in Down syndrome and in Alzheimer's disease
-
Kalman J, Juhasz A, Laird G, et al. Serum interleukin-6 levels correlate with the severity of dementia in Down syndrome and in Alzheimer's disease. Acta Neurol Scand 1997; 96: 236-40.
-
(1997)
Acta Neurol Scand
, vol.96
, pp. 236-240
-
-
Kalman, J.1
Juhasz, A.2
Laird, G.3
-
96
-
-
13144258727
-
Serotonin-immune interactions in elderly volunteers and in patients with Alzheimer's disease (DAT): Lower plasma tryptophan availability to the brain in the elderly and increased serum interleukin-6 in DAT
-
Bonaccorso S, Lin A, Song C, et al. Serotonin-immune interactions in elderly volunteers and in patients with Alzheimer's disease (DAT): lower plasma tryptophan availability to the brain in the elderly and increased serum interleukin-6 in DAT. Aging 1998; 10: 316-23.
-
(1998)
Aging
, vol.10
, pp. 316-323
-
-
Bonaccorso, S.1
Lin, A.2
Song, C.3
-
97
-
-
0029417080
-
Interleukin-1β and interleukin-6 are elevated in the cerebrospinal fluid of Alzheimer's and de novo Parkinson's disease patients
-
Blum-Degen D, Muller T, Kuhn W, et al. Interleukin-1β and interleukin-6 are elevated in the cerebrospinal fluid of Alzheimer's and de novo Parkinson's disease patients. Neurosci Lett 1995; 202: 17-20.
-
(1995)
Neurosci Lett
, vol.202
, pp. 17-20
-
-
Blum-Degen, D.1
Muller, T.2
Kuhn, W.3
-
98
-
-
0032513251
-
Serum interleukin-6 and interleukin-6 soluble receptor in Alzheimer's disease
-
Angelis P, Scharf S, Mander A, Vajda F, Christophidis N. Serum interleukin-6 and interleukin-6 soluble receptor in Alzheimer's disease. Neurosci Lett 1998; 244: 106-8.
-
(1998)
Neurosci Lett
, vol.244
, pp. 106-108
-
-
Angelis, P.1
Scharf, S.2
Mander, A.3
Vajda, F.4
Christophidis, N.5
-
99
-
-
0028465427
-
Serum cytokine levels in patients with Alzheimer's disease
-
Chao CC, Ala TA, Hu S, et al. Serum cytokine levels in patients with Alzheimer's disease. Clin Diagn Lab Immunol 1994; 1: 433-6.
-
(1994)
Clin Diagn Lab Immunol
, vol.1
, pp. 433-436
-
-
Chao, C.C.1
Ala, T.A.2
Hu, S.3
-
100
-
-
0025129231
-
Serum levels of interleukin-6 are not elevated in patients with Alzheimer's disease
-
Van Duijn CM, Hofman A, Nagelkerken L. Serum levels of interleukin-6 are not elevated in patients with Alzheimer's disease. Neurosci Lett 1990; 108: 350-4.
-
(1990)
Neurosci Lett
, vol.108
, pp. 350-354
-
-
van Duijn, C.M.1
Hofman, A.2
Nagelkerken, L.3
-
101
-
-
17644379605
-
Serum inflammatory proteins and cognitive decline in older persons
-
Dik MG, Jonker C, Hack CE, et al. Serum inflammatory proteins and cognitive decline in older persons. Neurology 2005; 64: 1371-7.
-
(2005)
Neurology
, vol.64
, pp. 1371-1377
-
-
Dik, M.G.1
Jonker, C.2
Hack, C.E.3
-
102
-
-
0036321773
-
Early inflammation and dementia: A 25-year follow-up of the Honolulu-Asia Aging Study
-
Schmidt R, Schmidt H, Curb JD, et al. Early inflammation and dementia: a 25-year follow-up of the Honolulu-Asia Aging Study. Ann Neurol 2002; 52: 168-74.
-
(2002)
Ann Neurol
, vol.52
, pp. 168-174
-
-
Schmidt, R.1
Schmidt, H.2
Curb, J.D.3
-
103
-
-
10744223280
-
Inflammatory markers and cognition in well-functioning African-American and white elders
-
Yaffe K, Lindquist K, Penninx BW, et al. Inflammatory markers and cognition in well-functioning African-American and white elders. Neurology 2003; 61: 76-80.
-
(2003)
Neurology
, vol.61
, pp. 76-80
-
-
Yaffe, K.1
Lindquist, K.2
Penninx, B.W.3
-
104
-
-
2442533101
-
Inflammatory proteins in plasma and the risk of dementia: The rotterdam study
-
Engelhart MJ, Geerlings MI, Meijer J, et al. Inflammatory proteins in plasma and the risk of dementia: the rotterdam study. Arch Neurol 2004; 61: 668-72.
-
(2004)
Arch Neurol
, vol.61
, pp. 668-672
-
-
Engelhart, M.J.1
Geerlings, M.I.2
Meijer, J.3
-
105
-
-
0035931293
-
Blood pressure, cognitive functions, and prevention of dementias in older patients with hypertension
-
Birkenhager WH, Forette F, et al. Blood pressure, cognitive functions, and prevention of dementias in older patients with hypertension. Arch Intern Med 2001; 161: 152-6.
-
(2001)
Arch Intern Med
, vol.161
, pp. 152-156
-
-
Birkenhager, W.H.1
Forette, F.2
-
106
-
-
0031976318
-
Serum total cholesterol, apolipoprotein E epsilon 4 allele, and Alzheimer's disease
-
Notkola IL, Sulkava R, Pekkanen J, et al. Serum total cholesterol, apolipoprotein E epsilon 4 allele, and Alzheimer's disease. Neuroepidemiology 1998; 17: 14-20.
-
(1998)
Neuroepidemiology
, vol.17
, pp. 14-20
-
-
Notkola, I.L.1
Sulkava, R.2
Pekkanen, J.3
-
107
-
-
0031026879
-
Atherosclerosis, apolipoprotein E, and prevalence of dementia and Alzheimer's disease in the Rotterdam Study
-
Hofman A, Ott A, Breteler MM, et al. Atherosclerosis, apolipoprotein E, and prevalence of dementia and Alzheimer's disease in the Rotterdam Study. Lancet 1997; 349: 151-4.
-
(1997)
Lancet
, vol.349
, pp. 151-154
-
-
Hofman, A.1
Ott, A.2
Breteler, M.M.3
-
108
-
-
0035897938
-
Midlife vascular risk factors and Alzheimer's disease in later life: Longitudinal, population-based study
-
Kivipelto M, Helkala EL, Laakso MP, et al. Midlife vascular risk factors and Alzheimer's disease in later life: longitudinal, population-based study. Br Med J 2001; 322: 1447-51.
-
(2001)
Br Med J
, vol.322
, pp. 1447-1451
-
-
Kivipelto, M.1
Helkala, E.L.2
Laakso, M.P.3
-
109
-
-
0033958076
-
Serum cholesterol, APOE genotype, and the risk of Alzheimer's disease: A population-based study of African Americans
-
Evans RM, Emsley CL, Gao S, et al. Serum cholesterol, APOE genotype, and the risk of Alzheimer's disease: a population-based study of African Americans. Neurology 2000; 54: 240-2.
-
(2000)
Neurology
, vol.54
, pp. 240-242
-
-
Evans, R.M.1
Emsley, C.L.2
Gao, S.3
-
110
-
-
0036186663
-
Serum lipoprotein levels, statin use, and cognitive function in older women
-
Yaffe K, Barrett-Connor E, Lin F, Grady D. Serum lipoprotein levels, statin use, and cognitive function in older women. Arch Neurol 2002; 59: 378-84.
-
(2002)
Arch Neurol
, vol.59
, pp. 378-384
-
-
Yaffe, K.1
Barrett-Connor, E.2
Lin, F.3
Grady, D.4
-
111
-
-
0029072551
-
Interactions of apolipoprotein E genotype, total cholesterol level, age, and sex in prediction of Alzheimer's disease: A case-control study
-
Jarvik GP, Wijsman EM, Kukull WA, et al. Interactions of apolipoprotein E genotype, total cholesterol level, age, and sex in prediction of Alzheimer's disease: a case-control study. Neurology 1999; 45: 1092-6.
-
(1999)
Neurology
, vol.45
, pp. 1092-1096
-
-
Jarvik, G.P.1
Wijsman, E.M.2
Kukull, W.A.3
-
113
-
-
0029066299
-
Quantitative assessment of plasma homocysteine as a risk factor for vascular disease; Probable benefits of increasing folic acid intakes
-
Boushey CJ, Beresford SA, Omenn GS, Motulsky AGA. Quantitative assessment of plasma homocysteine as a risk factor for vascular disease; Probable benefits of increasing folic acid intakes. JAMA 1995; 274: 1049-57.
-
(1995)
JAMA
, vol.274
, pp. 1049-1057
-
-
Boushey, C.J.1
Beresford, S.A.2
Omenn, G.S.3
Motulsky, A.G.A.4
-
114
-
-
0037075257
-
Plasma homocysteine as a risk factor for dementia and Alzheimer's disease
-
Seshadri S, Beiser A, Selhub J, et al. Plasma homocysteine as a risk factor for dementia and Alzheimer's disease. N Engl J Med 2002; 346: 476-83.
-
(2002)
N Engl J Med
, vol.346
, pp. 476-483
-
-
Seshadri, S.1
Beiser, A.2
Selhub, J.3
-
116
-
-
0036138648
-
24S-hydroxycholesterol in cerebrospinal fluid is elevated in early stages of dementia
-
Papassotiropoulos A, Lutjohann D, Bagli M, et al. 24S-hydroxycholesterol in cerebrospinal fluid is elevated in early stages of dementia. J Psychiatr Res 2002; 36: 27-32.
-
(2002)
J Psychiatr Res
, vol.36
, pp. 27-32
-
-
Papassotiropoulos, A.1
Lutjohann, D.2
Bagli, M.3
-
117
-
-
0037052771
-
Cerebrospinal fluid 24S-hydroxycholesterol is increased in patients with Alzheimer's disease compared to healthy controls
-
Schonknecht P, Lutjohann D, Pantel J, et al. Cerebrospinal fluid 24S-hydroxycholesterol is increased in patients with Alzheimer's disease compared to healthy controls. Neurosci Lett 2002; 324: 83-5.
-
(2002)
Neurosci Lett
, vol.324
, pp. 83-85
-
-
Schonknecht, P.1
Lutjohann, D.2
Pantel, J.3
-
118
-
-
0343775806
-
Plasma 24S-hydroxycholesterol (cerebrosterol) is increased in Alzheimer and vascular demented patients
-
Lutjohann D, Papassotiropoulos A, Bjorkhem I, et al. Plasma 24S-hydroxycholesterol (cerebrosterol) is increased in Alzheimer and vascular demented patients. J Lipid Res 2000; 41: 195-8.
-
(2000)
J Lipid Res
, vol.41
, pp. 195-198
-
-
Lutjohann, D.1
Papassotiropoulos, A.2
Bjorkhem, I.3
-
119
-
-
0027327267
-
Association of apolipoprotein E allele&4 with late-onset familial and sporadic Alzheimer's disease
-
Saunders A, Strittmater W, Schmechel D, et al. Association of apolipoprotein E allele&4 with late-onset familial and sporadic Alzheimer's disease. Neurology 1993; 43: 1467-72.
-
(1993)
Neurology
, vol.43
, pp. 1467-1472
-
-
Saunders, A.1
Strittmater, W.2
Schmechel, D.3
-
120
-
-
0030050286
-
Clinical and pathological correlates of apolipoprotein E & 4 in Alzheimer's disease
-
Gomez-Isla T, West HL, Rebeck GW, et al. Clinical and pathological correlates of apolipoprotein E & 4 in Alzheimer's disease. Ann Neurol 1996; 39: 62-70.
-
(1996)
Ann Neurol
, vol.39
, pp. 62-70
-
-
Gomez-Isla, T.1
West, H.L.2
Rebeck, G.W.3
-
121
-
-
0343247789
-
Preferential deposition of amyloid beta protein (Aβ) in the form Aβ40 in Alzheimer's disease is associated with a gene dosage effect of the apolipoprotein E &4 allele
-
Mann DM, Iwatsubo T, Pickering-Brown SM, et al. Preferential deposition of amyloid beta protein (Aβ) in the form Aβ40 in Alzheimer's disease is associated with a gene dosage effect of the apolipoprotein E &4 allele. Neurosci Lett 1997; 221: 81-4.
-
(1997)
Neurosci Lett
, vol.221
, pp. 81-84
-
-
Mann, D.M.1
Iwatsubo, T.2
Pickering-Brown, S.M.3
-
122
-
-
0028305380
-
Protective effect of apolipoprotein E type 2 allele for late onset Alzheimer disease
-
Corder EH, Saunders AM, Risch NJ, et al. Protective effect of apolipoprotein E type 2 allele for late onset Alzheimer disease. Nat Genet 1994; 7: 180-4.
-
(1994)
Nat Genet
, vol.7
, pp. 180-184
-
-
Corder, E.H.1
Saunders, A.M.2
Risch, N.J.3
-
123
-
-
34547813002
-
Serum biomarkers for Alzheimer's disease: Proteomic discovery
-
German DC, Gurnani P, Nandi A, et al. Serum biomarkers for Alzheimer's disease: proteomic discovery. Biomed Pharmacother 2007; 61: 383-9.
-
(2007)
Biomed Pharmacother
, vol.61
, pp. 383-389
-
-
German, D.C.1
Gurnani, P.2
Nandi, A.3
-
124
-
-
3242716703
-
Mild cognitive impairment, amnestic type: An epidemiologic study
-
Ganguli M, Dodge HH, Shen C, DeKosky ST. Mild cognitive impairment, amnestic type: an epidemiologic study. Neurology 2004; 63: 115-21.
-
(2004)
Neurology
, vol.63
, pp. 115-121
-
-
Ganguli, M.1
Dodge, H.H.2
Shen, C.3
Dekosky, S.T.4
-
126
-
-
29144508843
-
Global prevalence of dementia: A Delphi consensus study
-
Ferri CP, Prince M, Brayne C, et al. Global prevalence of dementia: a Delphi consensus study. Lancet 2005; 366: 2112-7.
-
(2005)
Lancet
, vol.366
, pp. 2112-2117
-
-
Ferri, C.P.1
Prince, M.2
Brayne, C.3
-
127
-
-
8844273984
-
Impact of APOE in mild cognitive impairment
-
Farlow MR, He Y, Tekin S, et al. Impact of APOE in mild cognitive impairment. Neurology 2004; 63: 1898-901.
-
(2004)
Neurology
, vol.63
, pp. 1898-1901
-
-
Farlow, M.R.1
He, Y.2
Tekin, S.3
-
128
-
-
0842309993
-
Increased risk of type 2 diabetes in Alzheimer disease
-
Janson J, Laedtke T, Parisi JE, et al. Increased risk of type 2 diabetes in Alzheimer disease. Diabetes 2004; 53: 474-81.
-
(2004)
Diabetes
, vol.53
, pp. 474-481
-
-
Janson, J.1
Laedtke, T.2
Parisi, J.E.3
-
129
-
-
0019791484
-
Pseudocholinesterase in obesity: Hypercaloric diet induced changes in experimental obese mice
-
Kutty KM, Huang SN, Kean KT. Pseudocholinesterase in obesity: hypercaloric diet induced changes in experimental obese mice. Experimentia 1981; 37: 1141-2.
-
(1981)
Experimentia
, vol.37
, pp. 1141-1142
-
-
Kutty, K.M.1
Huang, S.N.2
Kean, K.T.3
-
130
-
-
0028238432
-
Serum pseudocholinesterase and verylow density lipoprotein metabolism
-
Kutty KM, Payne RH. Serum pseudocholinesterase and verylow density lipoprotein metabolism. J Clin Lab Anal 1994; 8; 247-50.
-
(1994)
J Clin Lab Anal
, vol.8
, pp. 247-250
-
-
Kutty, K.M.1
Payne, R.H.2
-
131
-
-
28044437122
-
Selective butyrylcholinesterase inhibition elevated brain acetylcholine, augments learning and lowers Alzheimer beta-amyloid peptide in rodent
-
Greig NH, Utsuki T, Ingram DK, et al. Selective butyrylcholinesterase inhibition elevated brain acetylcholine, augments learning and lowers Alzheimer beta-amyloid peptide in rodent. Proc Natl Acad Sci USA 2005; 102: 17213-8.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 17213-17218
-
-
Greig, N.H.1
Utsuki, T.2
Ingram, D.K.3
-
132
-
-
0030731562
-
Synergy between the genes for butyrylcholinesterase K variant and apolipoprotein E4 in late-onset confirmed Alzheimer's disease
-
Lehmann DJ, Johnston C, Smith AD. Synergy between the genes for butyrylcholinesterase K variant and apolipoprotein E4 in late-onset confirmed Alzheimer's disease. Hum Molec Genet 1997; 6: 1933-6.
-
(1997)
Hum Molec Genet
, vol.6
, pp. 1933-1936
-
-
Lehmann, D.J.1
Johnston, C.2
Smith, A.D.3
-
133
-
-
26244447905
-
Serum butyrylcholinesterase in type 2 diabetes mellitus: A biochemical and bioinformatics approach
-
Sridhar GR, Nirmala G, Allam AR, et al. Serum butyrylcholinesterase in type 2 diabetes mellitus: a biochemical and bioinformatics approach. Lipid Health Dis 2005; 4: 18.
-
(2005)
Lipid Health Dis
, vol.4
, pp. 18
-
-
Sridhar, G.R.1
Nirmala, G.2
Allam, A.R.3
-
134
-
-
0033791856
-
Dipeptidyl carboxypeptidase 1 (Dcp1) and butyrylcholinesterase (BCHE) gene interactions with the apolipoprotein E epsison4 allele as risk factors in Alzheimer's disease and in Parkinson's disease with coexisting Alzheimer pathology
-
Mattila KM, Rinne Jom Roytta M, Laippala P, et al. Dipeptidyl carboxypeptidase 1 (Dcp1) and butyrylcholinesterase (BCHE) gene interactions with the apolipoprotein E epsison4 allele as risk factors in Alzheimer's disease and in Parkinson's disease with coexisting Alzheimer pathology. J Med Genet 2000; 37: 766-70.
-
(2000)
J Med Genet
, vol.37
, pp. 766-770
-
-
Mattila, K.M.1
Rinne, J.R.M.2
Laippala, P.3
-
135
-
-
7444260921
-
Analysis of association between butyrylcholinesterase K variant and apolipoprotein E genotypes in Alzheimer's disease
-
Raygani AV, Zahrai M, Soltanzadeh A, et al. Analysis of association between butyrylcholinesterase K variant and apolipoprotein E genotypes in Alzheimer's disease. Neurosci Lett 2004; 371: 142-6.
-
(2004)
Neurosci Lett
, vol.371
, pp. 142-146
-
-
Raygani, A.V.1
Zahrai, M.2
Soltanzadeh, A.3
-
136
-
-
85039557358
-
-
In Lipid disorders Edited by: Tripathy BB, Das S. Assocsiation of Physicians of India, API College of Physicians
-
Sridhar GR, Nirmala G. Inborn errors in lipid metabolism. In Lipid disorders Edited by: Tripathy BB, Das S. Assocsiation of Physicians of India, API College of Physicians; 2002; pp. 59-80.
-
Inborn errors in lipid metabolism
, vol.2002
, pp. 59-80
-
-
Sridhar, G.R.1
Nirmala, G.2
-
137
-
-
33745143582
-
A computational study of deacylation mechanism of human butyrylcholinesterase
-
Suarez D, Diaz N, Camps JF, Field MJ. A computational study of deacylation mechanism of human butyrylcholinesterase. Biochemistry 2006; 45: 7529-43.
-
(2006)
Biochemistry
, vol.45
, pp. 7529-7543
-
-
Suarez, D.1
Diaz, N.2
Camps, J.F.3
Field, M.J.4
-
138
-
-
0034942187
-
Is pseudocholinesterase activity related to markers of triacylglycerol synthesis in type II diabetes mellitus?
-
Rustemeijer C, Schouten JA, Voerman HJ, et al. Is pseudocholinesterase activity related to markers of triacylglycerol synthesis in type II diabetes mellitus? Clin Sci 2001; 101: 29-35.
-
(2001)
Clin Sci
, vol.101
, pp. 29-35
-
-
Rustemeijer, C.1
Schouten, J.A.2
Voerman, H.J.3
-
139
-
-
33750297576
-
Effect of butyrylcholinesterase genotype on the response to rivastigmine or donepezil in younger patients with Alzheimer's disease
-
Blesa R, Bullock R, He Y, et al. Effect of butyrylcholinesterase genotype on the response to rivastigmine or donepezil in younger patients with Alzheimer's disease. Pharmacogenet Genom 2006; 16: 771-4.
-
(2006)
Pharmacogenet Genom
, vol.16
, pp. 771-774
-
-
Blesa, R.1
Bullock, R.2
He, Y.3
-
140
-
-
42749100518
-
Cholinesterase inhibitors for Alzheimer's disease
-
Birks J. Cholinesterase inhibitors for Alzheimer's disease. Cochrane Data Syst Rev 2006; CD005593.
-
(2006)
Cochrane Data Syst Rev
-
-
Birks, J.1
-
141
-
-
33745015720
-
Butyrylcholinesterase attenuates amyloid fibril formation in vitro
-
Diamant S, Podoly E, Friedler A, et al. Butyrylcholinesterase attenuates amyloid fibril formation in vitro. Proc Natl Acad Sci USA 2006; 103: 8628-33.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 8628-8633
-
-
Diamant, S.1
Podoly, E.2
Friedler, A.3
-
142
-
-
4544290582
-
Large-scale studies of the functional K variant of the butyrylcholinesterase gene in relation to Type 2 diabetes and insulin secretion
-
Johansen AEM, Nielsen D, Andersen G, et al. Large-scale studies of the functional K variant of the butyrylcholinesterase gene in relation to Type 2 diabetes and insulin secretion. Diabetologia 2004; 47: 1437-41.
-
(2004)
Diabetologia
, vol.47
, pp. 1437-1441
-
-
Johansen, A.E.M.1
Nielsen, D.2
Andersen, G.3
-
143
-
-
0033652271
-
Genomewise search for type 2 diabetes susceptibility genes in French Whites: Evidence for a novel susceptibility locus for early-onset diabetes on chromosome 3q27-qter and independent replication of a type 2 diabetes locus on chromosome 1q21-q24
-
Vionnet N, Hani EH, Dupont S, et al. Genomewise search for type 2 diabetes susceptibility genes in French Whites: evidence for a novel susceptibility locus for early-onset diabetes on chromosome 3q27-qter and independent replication of a type 2 diabetes locus on chromosome 1q21-q24. Am J Hum Genet 2000; 67: 1470-80.
-
(2000)
Am J Hum Genet
, vol.67
, pp. 1470-1480
-
-
Vionnet, N.1
Hani, E.H.2
Dupont, S.3
-
144
-
-
33747104566
-
Links between Alzheimer's disease and diabetes
-
Sun MK, Alkon DL. Links between Alzheimer's disease and diabetes. Drugs Today 2006; 42: 481-9.
-
(2006)
Drugs Today
, vol.42
, pp. 481-489
-
-
Sun, M.K.1
Alkon, D.L.2
-
145
-
-
1542752823
-
Does diabetes protect or provoke Alzheimer's disease? Insights into the pathobiology and future treatment of Alzheimer's disease
-
Grossman H. Does diabetes protect or provoke Alzheimer's disease? Insights into the pathobiology and future treatment of Alzheimer's disease. CNS Spectr 2003; 8: 815-23.
-
(2003)
CNS Spectr
, vol.8
, pp. 815-823
-
-
Grossman, H.1
-
146
-
-
23244450772
-
Relationship between serum butyrylcholinesterase and the metabolic syndrome
-
Randell EW, Mathews MS, Zhang H, Seraj JS, Sun G. Relationship between serum butyrylcholinesterase and the metabolic syndrome. Clin Biochem 2005; 38: 799-805.
-
(2005)
Clin Biochem
, vol.38
, pp. 799-805
-
-
Randell, E.W.1
Mathews, M.S.2
Zhang, H.3
Seraj, J.S.4
Sun, G.5
-
147
-
-
75149178824
-
Insulin resistance in Alzheimer's disease - a novel therapeutic target. Alzheimer's disease and related disorders Annual 5
-
London
-
Craft S, Reger MA, Baker LD. Insulin resistance in Alzheimer's disease - a novel therapeutic target. Alzheimer's disease and related disorders Annual 5. Taylor and Francis, London 2006; pp. 111-33.
-
(2006)
Taylor and Francis
, pp. 111-133
-
-
Craft, S.1
Reger, M.A.2
Baker, L.D.3
-
148
-
-
84860520259
-
GSK3: A key target for the development of novel treatments for type 2 diabetes mellitus and Alzheimer disease
-
Gao C, Holscher C, Liu Y, Li L. GSK3: a key target for the development of novel treatments for type 2 diabetes mellitus and Alzheimer disease. Rev Neurosci 2011; 23(1): 1-11.
-
(2011)
Rev Neurosci
, vol.23
, Issue.1
, pp. 1-11
-
-
Gao, C.1
Holscher, C.2
Liu, Y.3
Li, L.4
-
149
-
-
0036090823
-
Glycogen synthase kinase 3: An emerging therapeutic target
-
Eldar-Finkelman H. Glycogen synthase kinase 3: an emerging therapeutic target. Trends Mol Med 2002; 8(3): 126-32.
-
(2002)
Trends Mol Med
, vol.8
, Issue.3
, pp. 126-132
-
-
Eldar-Finkelman, H.1
-
150
-
-
0442276554
-
The glamour and gloom of glycogen synthase kinase-3
-
Jope RS, Johnson GV. The glamour and gloom of glycogen synthase kinase-3. Trends Biochem Sci 2004; 29(2): 95-102.
-
(2004)
Trends Biochem Sci
, vol.29
, Issue.2
, pp. 95-102
-
-
Jope, R.S.1
Johnson, G.V.2
-
151
-
-
33947597084
-
Glycogen synthase kinase-3 (GSK3): Inflammation, diseases, and therapeutics
-
Jope RS, Yuskaitis CJ, Beurel E. Glycogen synthase kinase-3 (GSK3): inflammation, diseases, and therapeutics. Neurochem Res 2007; 32(4-5): 577-95.
-
(2007)
Neurochem Res
, vol.32
, Issue.4-5
, pp. 577-595
-
-
Jope, R.S.1
Yuskaitis, C.J.2
Beurel, E.3
-
152
-
-
84861023806
-
Small-Molecule Inhibitors of GSK-3: Structural Insights and Their Application to Alzheimer's Disease Models
-
Kramer T, Schmidt B, Lo Monte F. Small-Molecule Inhibitors of GSK-3: Structural Insights and Their Application to Alzheimer's Disease Models. Int J Alzheimers Dis 2012; 2012: 381029.
-
(2012)
Int J Alzheimers Dis
, vol.2012
, pp. 381029
-
-
Kramer, T.1
Schmidt, B.2
Lo Monte, F.3
-
153
-
-
58149479354
-
GSK3 inhibitors show benefits in an Alzheimer's disease (AD) model of neurodegeneration but adverse effects in control animals
-
Hu S, Begum AN, Jones MR, et al. GSK3 inhibitors show benefits in an Alzheimer's disease (AD) model of neurodegeneration but adverse effects in control animals. Neurobiol Dis 2009; 33(2): 193-206.
-
(2009)
Neurobiol Dis
, vol.33
, Issue.2
, pp. 193-206
-
-
Hu, S.1
Begum, A.N.2
Jones, M.R.3
-
154
-
-
67650569513
-
Glycogen synthase kinase 3: More than a namesake
-
Rayasam GV, Tulasi VK, Sodhi R, Davis JA, Ray A. Glycogen synthase kinase 3: more than a namesake. Br J Pharmacol 2009; 156(6): 885-98.
-
(2009)
Br J Pharmacol
, vol.156
, Issue.6
, pp. 885-898
-
-
Rayasam, G.V.1
Tulasi, V.K.2
Sodhi, R.3
Davis, J.A.4
Ray, A.5
-
155
-
-
80052737323
-
Glucagon-Like Peptide-1: Diabetes, and Cognitive Decline: Possible Pathophysiological Links and Therapeutic Opportunitie
-
Mossello E, Ballini E, Boncinelli M, et al. Glucagon-Like Peptide-1: Diabetes, and Cognitive Decline: Possible Pathophysiological Links and Therapeutic Opportunitie. Exp Dia Res 2011; 2011: 281674.
-
(2011)
Exp Dia Res
, vol.2011
, pp. 281674
-
-
Mossello, E.1
Ballini, E.2
Boncinelli, M.3
-
156
-
-
0022617246
-
Reduced incretin effect in Type 2 (non-insulin-dependent) diabetes
-
Nauck M, Stockmann F, Ebert R, Creutzfeldt W. Reduced incretin effect in Type 2 (non-insulin-dependent) diabetes. Diabetologia 1986; 29(1): 46-52.
-
(1986)
Diabetologia
, vol.29
, Issue.1
, pp. 46-52
-
-
Nauck, M.1
Stockmann, F.2
Ebert, R.3
Creutzfeldt, W.4
-
157
-
-
0033739493
-
Glucagon-like peptide (GLP)-1 and leptin concentrations in obese patients with Type 2 diabetes mellitus
-
Mannucci E, Ognibene A, Cremasco F, et al. Glucagon-like peptide (GLP)-1 and leptin concentrations in obese patients with Type 2 diabetes mellitus. Diabetic Med 2000; 17(10): 713-9.
-
(2000)
Diabetic Med
, vol.17
, Issue.10
, pp. 713-719
-
-
Mannucci, E.1
Ognibene, A.2
Cremasco, F.3
-
158
-
-
0001095690
-
Reduced postprandial concentrations of intact biologically active glucagon-like peptide 1 in type 2 diabetic patients
-
Vilsbøll T, Krarup T Deacon CF, Madsbad S, Holst JJ. Reduced postprandial concentrations of intact biologically active glucagon-like peptide 1 in type 2 diabetic patients. Diabetes 2001; 50(3): 609-13.
-
(2001)
Diabetes
, vol.50
, Issue.3
, pp. 609-613
-
-
Vilsbøll, T.1
Krarup, T.D.C.F.2
Madsbad, S.3
Holst, J.J.4
-
159
-
-
0035462466
-
Impaired incretin response after a mixed meal is associated with insulin resistance in nondiabetic men
-
Rask E, Olsson T, Söderberg S, et al. Impaired incretin response after a mixed meal is associated with insulin resistance in nondiabetic men. Diab Care 2001; 24(9): 1640-5.
-
(2001)
Diab Care
, vol.24
, Issue.9
, pp. 1640-1645
-
-
Rask, E.1
Olsson, T.2
Söderberg, S.3
-
160
-
-
2342642148
-
Insulin secretion and incretin hormones after oral glucose in non-obese subjects with impaired glucose tolerance
-
Rask E, Olsson T, Söderberg S, et al. Insulin secretion and incretin hormones after oral glucose in non-obese subjects with impaired glucose tolerance. Metabolism 2004; 53(5): 624-31.
-
(2004)
Metabolism
, vol.53
, Issue.5
, pp. 624-631
-
-
Rask, E.1
Olsson, T.2
Söderberg, S.3
-
161
-
-
77950352189
-
GLP-1 receptor stimulation reduces amyloid-β peptide accumulation and cytotoxicity in cellular and animal models of Alzheimer's disease
-
Li Y, Duffy KB, Ottinger MA, et al. GLP-1 receptor stimulation reduces amyloid-β peptide accumulation and cytotoxicity in cellular and animal models of Alzheimer's disease. J Alzheimers Dis 2010; 19(4): 1205-19.
-
(2010)
J Alzheimers Dis
, vol.19
, Issue.4
, pp. 1205-1219
-
-
Li, Y.1
Duffy, K.B.2
Ottinger, M.A.3
-
162
-
-
77649187436
-
Glucagon-like peptide-1 analogues enhance synaptic plasticity in the brain: A link between diabetes and Alzheimer's disease
-
McClean PL, Gault VA, Harriott P, Hölscher C. Glucagon-like peptide-1 analogues enhance synaptic plasticity in the brain: a link between diabetes and Alzheimer's disease. Eur J Pharmacol 2010; 630(1-3): 158-62.
-
(2010)
Eur J Pharmacol
, vol.630
, Issue.1-3
, pp. 158-162
-
-
McClean, P.L.1
Gault, V.A.2
Harriott, P.3
Hölscher, C.4
-
163
-
-
79751479118
-
Novel GLP-1 mimetics developed to treat type 2 diabetes promote progenitor cell proliferation in the brain
-
Hamilton A, Patterson S, Porter D, Gault VA, Hölscher C. Novel GLP-1 mimetics developed to treat type 2 diabetes promote progenitor cell proliferation in the brain. J Neuro Res 2011; 89(4): 481-9.
-
(2011)
J Neuro Res
, vol.89
, Issue.4
, pp. 481-489
-
-
Hamilton, A.1
Patterson, S.2
Porter, D.3
Gault, V.A.4
Hölscher, C.5
-
164
-
-
33846019607
-
Beta-amyloid treatment of two complementary P301L tau-expressing Alzheimer's disease models reveals similar deregulated cellular processes
-
David DC, Ittner LM, Gehrig P, et al. Beta-amyloid treatment of two complementary P301L tau-expressing Alzheimer's disease models reveals similar deregulated cellular processes. Proteomics 2006; 6: 6566-77.
-
(2006)
Proteomics
, vol.6
, pp. 6566-6577
-
-
David, D.C.1
Ittner, L.M.2
Gehrig, P.3
-
165
-
-
0034640372
-
Alzheimer's-amyloid, human islet amylin and prion protein fragment evoke intracellular free calcium elevations by a common mechanism in a hypothalamic GnRH neuronal cell line
-
Kawahara M, Kuroda Y, Arispe N, Rojas E. Alzheimer's-amyloid, human islet amylin and prion protein fragment evoke intracellular free calcium elevations by a common mechanism in a hypothalamic GnRH neuronal cell line. J Biol Chem 2000; 274: 14077-83.
-
(2000)
J Biol Chem
, vol.274
, pp. 14077-14083
-
-
Kawahara, M.1
Kuroda, Y.2
Arispe, N.3
Rojas, E.4
-
166
-
-
0036381074
-
Ion channel formation and membrane-linked pathologies of misfolded hydrophobic proteins: The role of dangerous unchaperoned molecules
-
Kourie JI, Henry CL. Ion channel formation and membrane-linked pathologies of misfolded hydrophobic proteins: the role of dangerous unchaperoned molecules. Clin Exp Pharmacol Physiol 2002; 29: 741-53.
-
(2002)
Clin Exp Pharmacol Physiol
, vol.29
, pp. 741-753
-
-
Kourie, J.I.1
Henry, C.L.2
-
167
-
-
44749083630
-
Human but not rat amylin shares neurotoxic propertieswith Abeta42 in long-term hippocampal and cortical cultures
-
Lim YA, Ittner LM, Lim YL, Gotz J. Human but not rat amylin shares neurotoxic propertieswith Abeta42 in long-term hippocampal and cortical cultures. FEBS Lett 2008; 582: 2188-94.
-
(2008)
FEBS Lett
, vol.582
, pp. 2188-2194
-
-
Lim, Y.A.1
Ittner, L.M.2
Lim, Y.L.3
Gotz, J.4
-
168
-
-
0028303844
-
Pancreatic islet cell toxicity of amylin associated with type-2 diabetes mellitus
-
Lorenzo A, Razzaboni B, Weir GC, Yankner BA. Pancreatic islet cell toxicity of amylin associated with type-2 diabetes mellitus. Nature 1994; 368(6473): 756-60.
-
(1994)
Nature
, vol.368
, Issue.6473
, pp. 756-760
-
-
Lorenzo, A.1
Razzaboni, B.2
Weir, G.C.3
Yankner, B.A.4
-
169
-
-
77951044468
-
Abeta and human amylin share a common toxicity pathway via mitochondrial dysfunction
-
Lim YA, Rhein V, Baysang G, et al. Abeta and human amylin share a common toxicity pathway via mitochondrial dysfunction. Proteomics 2010; 10(8): 1621-33.
-
(2010)
Proteomics
, vol.10
, Issue.8
, pp. 1621-1633
-
-
Lim, Y.A.1
Rhein, V.2
Baysang, G.3
-
170
-
-
1542407369
-
Brain metabolic decreases related to the dose of the ApoE e4 allele in Alzheimer's disease
-
Mosconi L, Nacmias B, Sorbi S, et al. Brain metabolic decreases related to the dose of the ApoE e4 allele in Alzheimer's disease. J Neurol Neurosurg Psychiatry 2004; 75: 370-6.
-
(2004)
J Neurol Neurosurg Psychiatry
, vol.75
, pp. 370-376
-
-
Mosconi, L.1
Nacmias, B.2
Sorbi, S.3
-
171
-
-
10944240913
-
Metabolic interaction between ApoE genotype and onset age in Alzheimer's disease: Implications for brain reserve
-
Mosconi L, Herholz K, Prohovnik I, et al. Metabolic interaction between ApoE genotype and onset age in Alzheimer's disease: implications for brain reserve. J Neurol Neurosurg Psychiatry 2005; 76: 15-23.
-
(2005)
J Neurol Neurosurg Psychiatry
, vol.76
, pp. 15-23
-
-
Mosconi, L.1
Herholz, K.2
Prohovnik, I.3
-
172
-
-
38349059065
-
Enhanced risk for Alzheimer disease in persons with type 2 diabetes and APOE epsilon4: The Cardiovascular Health Study Cognition Study
-
Irie F, Fitzpatrick AL, Lopez OL, et al. Enhanced risk for Alzheimer disease in persons with type 2 diabetes and APOE epsilon4: the Cardiovascular Health Study Cognition Study. Arch Neurol 2008; 65: 89-93.
-
(2008)
Arch Neurol
, vol.65
, pp. 89-93
-
-
Irie, F.1
Fitzpatrick, A.L.2
Lopez, O.L.3
-
173
-
-
0346101885
-
Enhanced proteolysis of beta-amyloid in APP transgenic mice prevents plaque formation, secondary pathology, and premature death
-
Leissring MA, Farris W, Chang AY, et al. Enhanced proteolysis of beta-amyloid in APP transgenic mice prevents plaque formation, secondary pathology, and premature death. Neuron 2003; 40: 1087-93.
-
(2003)
Neuron
, vol.40
, pp. 1087-1093
-
-
Leissring, M.A.1
Farris, W.2
Chang, A.Y.3
-
174
-
-
29844432266
-
Insulin, insulin-degrading enzyme and amyloid-beta peptide in Alzheimer's disease: Review and hypothesis
-
Qiu WQ, Folstein MF. Insulin, insulin-degrading enzyme and amyloid-beta peptide in Alzheimer's disease: review and hypothesis. Neurobiol Aging 2006; 27: 190-8.
-
(2006)
Neurobiol Aging
, vol.27
, pp. 190-198
-
-
Qiu, W.Q.1
Folstein, M.F.2
-
175
-
-
80155167222
-
Rosiglitazone and pioglitazone for the treatment of Alzheimer's disease
-
Miller BW, Willett KC, Desilets AR. Rosiglitazone and pioglitazone for the treatment of Alzheimer's disease. Ann Pharmacother 2011; 45(11): 1416-24.
-
(2011)
Ann Pharmacother
, vol.45
, Issue.11
, pp. 1416-1424
-
-
Miller, B.W.1
Willett, K.C.2
Desilets, A.R.3
-
176
-
-
0033608169
-
Increased expression of cyclooxygenases and peroxisome proliferator-activated receptor-gamma in Alzheimer's disease brains
-
Kitamura Y, Shimohama S, Koike H, et al. Increased expression of cyclooxygenases and peroxisome proliferator-activated receptor-gamma in Alzheimer's disease brains. Biochem Biophys Res Commun 1999; 254: 582-6.
-
(1999)
Biochem Biophys Res Commun
, vol.254
, pp. 582-586
-
-
Kitamura, Y.1
Shimohama, S.2
Koike, H.3
-
177
-
-
0036183630
-
The mechanisms of action of PPARs
-
Berger J, Moller DE. The mechanisms of action of PPARs. Annu Rev Med 2002; 53: 409-35.
-
(2002)
Annu Rev Med
, vol.53
, pp. 409-435
-
-
Berger, J.1
Moller, D.E.2
-
178
-
-
78651322583
-
A Randomized Pilot Clinical Trial of the Safety of Pioglitazone in Treatment of Patients with Alzheimer Disease
-
Geldmacher DS, Fritsch T, McClendon MJ, Landreth G. A Randomized Pilot Clinical Trial of the Safety of Pioglitazone in Treatment of Patients with Alzheimer Disease. Arch Neurol 2011; 68(1): 45-50.
-
(2011)
Arch Neurol
, vol.68
, Issue.1
, pp. 45-50
-
-
Geldmacher, D.S.1
Fritsch, T.2
McClendon, M.J.3
Landreth, G.4
-
179
-
-
79959479102
-
Efficacy of PPAR-γ agonist pioglitazone in mild Alzheimer disease
-
Sato T, Hanyu H, Hirao K, et al. Efficacy of PPAR-γ agonist pioglitazone in mild Alzheimer disease. Neurobiol Aging 2011; 32(9): 1626-33.
-
(2011)
Neurobiol Aging
, vol.32
, Issue.9
, pp. 1626-1633
-
-
Sato, T.1
Hanyu, H.2
Hirao, K.3
-
180
-
-
79251623365
-
Diabetes mellitus and Alzheimer's disease: Shared pathology and treatment?
-
Akter K, Lanza EA, Martin SA, et al. Diabetes mellitus and Alzheimer's disease: shared pathology and treatment? Br J Clin Pharmacol 2011; 71(3): 365-76.
-
(2011)
Br J Clin Pharmacol
, vol.71
, Issue.3
, pp. 365-376
-
-
Akter, K.1
Lanza, E.A.2
Martin, S.A.3
-
181
-
-
84940266311
-
-
Columbia University, Institute for the Study of Aging, National Institute on Aging, Available at, (last verified and updated 12 April, last accessed 14 January 2013
-
Columbia University, Institute for the Study of Aging, National Institute on Aging. Metformin in amnestic mild cognitive impairment (MCI). Available at http://clinicaltrialsgov/ct2/show/NCT00620191; (last verified and updated 12 April 2011; last accessed 14 January 2013).
-
(2011)
Metformin In Amnestic Mild Cognitive Impairment (MCI)
-
-
-
182
-
-
84940246935
-
Effect of Insulin Sensitizer Metformin on Alzheimer's Disease Biomarkers
-
Clarksburg, MD, USA, Available from
-
Arnold SE. Effect of Insulin Sensitizer Metformin on Alzheimer's Disease Biomarkers. Bright focus foundation; Clarksburg, MD, USA 2012. Available from: http://www.brightfocus.org/research/grants/migrated/effect-of-insulin-sensitizer.html
-
(2012)
Bright Focus Foundation
-
-
Arnold, S.E.1
-
183
-
-
31844434789
-
Effects of intranasal insulin on cognition in memory-impaired older adults: Modulation by APOE genotype
-
Reger MA, Watson GS, Frey WH 2nd, et al. Effects of intranasal insulin on cognition in memory-impaired older adults: modulation by APOE genotype. Neurobiol Aging 2006; 27: 451-8.
-
(2006)
Neurobiol Aging
, vol.27
, pp. 451-458
-
-
Reger, M.A.1
Watson, G.S.2
Frey II, W.H.3
-
184
-
-
40349091597
-
Intranasal insulin improves cognition and modulates beta-amyloid in early AD
-
Reger MA, Watson GS, Green PS, et al. Intranasal insulin improves cognition and modulates beta-amyloid in early AD. Neurology 2008; 70: 440-8.
-
(2008)
Neurology
, vol.70
, pp. 440-448
-
-
Reger, M.A.1
Watson, G.S.2
Green, P.S.3
-
185
-
-
4744370969
-
Amyloid-induced neurofibrillary tangle formation in Alzheimer's disease: Insight from transgenic mouse and tissue-culture models
-
Gotz J, Schild A, Hoerndli F, Pennanen L. Amyloid-induced neurofibrillary tangle formation in Alzheimer's disease: Insight from transgenic mouse and tissue-culture models. Int J Dev Neurosci 2004; 22: 453-65.
-
(2004)
Int J Dev Neurosci
, vol.22
, pp. 453-465
-
-
Gotz, J.1
Schild, A.2
Hoerndli, F.3
Pennanen, L.4
|