Aβ and human amylin share a common toxicity pathway via mitochondrial dysfunction

Proteomics

Volumn 10, Issue 8, 2010, Pages 1621-1633

  Lim, Yun An ^a   Rhein, Virginie ^b   Baysang, Ginette ^b   Meier, Fides ^b   Poljak, Anne ^c   Raftery, Mark J ^c   Guilhaus, Michael ^c   Ittner, Lars M ^a   Eckert, Anne ^b   Götz, Jürgen ^a  

^a UNIVERSITY OF SYDNEY   (Australia)

^b UNIVERSITY OF BASEL   (Switzerland)

^c UNIVERSITY OF NEW SOUTH WALES   (Australia)

Author keywords

Alzheimer's disease; Amyloidosis; Mitochondrial complex proteins; Respiration; Type 2 diabetes mellitus

Indexed keywords

AMYLIN; AMYLOID BETA PROTEIN; CYTOCHROME C OXIDASE; INSULIN; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); AMYLOID;

ALZHEIMER DISEASE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; HUMAN; HUMAN CELL; INSULIN RELEASE; MITOCHONDRIAL RESPIRATION; MITOCHONDRIAL TOXICITY; MORBIDITY; MORTALITY; NON INSULIN DEPENDENT DIABETES MELLITUS; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEOMICS; QUANTITATIVE ANALYSIS; TARGET ORGAN; VALIDATION PROCESS; METABOLISM; MITOCHONDRION; OXYGEN CONSUMPTION; TUMOR CELL LINE;

RATTUS;

AMYLOID; AMYLOID BETA-PROTEIN; CELL LINE, TUMOR; HUMANS; MITOCHONDRIA; OXYGEN CONSUMPTION; REACTIVE OXYGEN SPECIES;

EID: 77951044468     PISSN: 16159853     EISSN: 16159861     Source Type: Journal    
DOI: 10.1002/pmic.200900651     Document Type: Article

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