메뉴 건너뛰기




Volumn 61, Issue 2, 2009, Pages 69-80

Plasma biomarkers for mild cognitive impairment and Alzheimer's disease

Author keywords

Alzheimer's disease; Amyloid beta; Biomarker; Mild cognitive impairment; Plasma; Proteomics

Indexed keywords

ALPHA 1 ANTITRYPSIN; ALPHA 2 MACROGLOBULIN; AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN[1-40]; AMYLOID BETA PROTEIN[1-42]; APOLIPOPROTEIN A1; APOLIPOPROTEIN B100; APOLIPOPROTEIN E; APOLIPOPROTEIN E4; CHOLESTEROL; CLUSTERIN; COMPLEMENT COMPONENT C3; COMPLEMENT COMPONENT C4; COMPLEMENT FACTOR H; DESMOPLAKIN; GALECTIN 7; HEMOGLOBIN ALPHA CHAIN; HEMOPEXIN; HISTONE H2B; HOMOCYSTEINE; INTERLEUKIN 1; MALONALDEHYDE; OROSOMUCOID; PLACEBO; PREALBUMIN; ROSIGLITAZONE; TRANSFERRIN; UNINDEXED DRUG; VALPROATE SEMISODIUM; VITAMIN D BINDING PROTEIN;

EID: 70349499185     PISSN: 01650173     EISSN: 18726321     Source Type: Journal    
DOI: 10.1016/j.brainresrev.2009.05.003     Document Type: Review
Times cited : (152)

References (107)
  • 4
    • 34247362877 scopus 로고    scopus 로고
    • Longitudinal change in cognitive performance among individuals with mild cognitive impairment
    • Albert M., Blacker D., Moss M.B., Tanzi R., and McArdle J.J. Longitudinal change in cognitive performance among individuals with mild cognitive impairment. Neuropsychology 21 (2007) 158-169
    • (2007) Neuropsychology , vol.21 , pp. 158-169
    • Albert, M.1    Blacker, D.2    Moss, M.B.3    Tanzi, R.4    McArdle, J.J.5
  • 9
    • 36048982129 scopus 로고    scopus 로고
    • Conversion from cognitive health to mild cognitive impairment and Alzheimer's disease: prediction by plasma amyloid beta 42, medial temporal lobe atrophy and homocysteine
    • Blasko I., Jellinger K., Kemmler G., Krampla W., Jungwirth S., Wichart I., Tragl K.H., and Fischer P. Conversion from cognitive health to mild cognitive impairment and Alzheimer's disease: prediction by plasma amyloid beta 42, medial temporal lobe atrophy and homocysteine. Neurobiol. Aging 29 (2008) 1-11
    • (2008) Neurobiol. Aging , vol.29 , pp. 1-11
    • Blasko, I.1    Jellinger, K.2    Kemmler, G.3    Krampla, W.4    Jungwirth, S.5    Wichart, I.6    Tragl, K.H.7    Fischer, P.8
  • 10
    • 33747075424 scopus 로고    scopus 로고
    • Mild cognitive impairment: risk of Alzheimer disease and rate of cognitive decline
    • Boyle P.A., Wilson R.S., Aggarwal N.T., Tang Y., and Bennett D.A. Mild cognitive impairment: risk of Alzheimer disease and rate of cognitive decline. Neurology 67 (2006) 441-445
    • (2006) Neurology , vol.67 , pp. 441-445
    • Boyle, P.A.1    Wilson, R.S.2    Aggarwal, N.T.3    Tang, Y.4    Bennett, D.A.5
  • 15
    • 31544471805 scopus 로고    scopus 로고
    • Proteome studies of CSF in AD patients
    • Davidsson P., and Sjogren M. Proteome studies of CSF in AD patients. Mech. Ageing Dev. 127 (2006) 133-137
    • (2006) Mech. Ageing Dev. , vol.127 , pp. 133-137
    • Davidsson, P.1    Sjogren, M.2
  • 20
    • 0037411512 scopus 로고    scopus 로고
    • Biological markers for therapeutic trials in Alzheimer's disease. Proceedings of the biological markers working group; NIA initiative on neuroimaging in Alzheimer's disease
    • Frank R.A., Galasko D., Hampel H., Hardy J., de Leon M.J., Mehta P.D., Rogers J., Siemers E., and Trojanowski J.Q. Biological markers for therapeutic trials in Alzheimer's disease. Proceedings of the biological markers working group; NIA initiative on neuroimaging in Alzheimer's disease. Neurobiol. Aging 24 (2003) 521-536
    • (2003) Neurobiol. Aging , vol.24 , pp. 521-536
    • Frank, R.A.1    Galasko, D.2    Hampel, H.3    Hardy, J.4    de Leon, M.J.5    Mehta, P.D.6    Rogers, J.7    Siemers, E.8    Trojanowski, J.Q.9
  • 23
    • 3242716703 scopus 로고    scopus 로고
    • Mild cognitive impairment, amnestic type: an epidemiologic study
    • Ganguli M., Dodge H.H., Shen C., and DeKosky S.T. Mild cognitive impairment, amnestic type: an epidemiologic study. Neurology 63 (2004) 115-121
    • (2004) Neurology , vol.63 , pp. 115-121
    • Ganguli, M.1    Dodge, H.H.2    Shen, C.3    DeKosky, S.T.4
  • 24
    • 0033921540 scopus 로고    scopus 로고
    • Complement components of the innate immune system in health and disease in the CNS
    • Gasque P., Dean Y.D., McGreal E.P., VanBeek J., and Morgan B.P. Complement components of the innate immune system in health and disease in the CNS. Immunopharmacology 49 (2000) 171-186
    • (2000) Immunopharmacology , vol.49 , pp. 171-186
    • Gasque, P.1    Dean, Y.D.2    McGreal, E.P.3    VanBeek, J.4    Morgan, B.P.5
  • 28
    • 0026601404 scopus 로고
    • Alpha 1-antitrypsin and alpha 1-antichymotrypsin are in the lesions of Alzheimer's disease
    • Gollin P.A., Kalaria R.N., Eikelenboom P., Rozemuller A., and Perry G. Alpha 1-antitrypsin and alpha 1-antichymotrypsin are in the lesions of Alzheimer's disease. Neuroreport 3 (1992) 201-203
    • (1992) Neuroreport , vol.3 , pp. 201-203
    • Gollin, P.A.1    Kalaria, R.N.2    Eikelenboom, P.3    Rozemuller, A.4    Perry, G.5
  • 32
    • 74149089257 scopus 로고    scopus 로고
    • Evaluation of plasma Abeta(40) and Abeta(42) as predictors of conversion to Alzheimer's disease in patients with mild cognitive impairment
    • doi:10.1016/j.neurobiolaging.2008.03.027
    • Hansson O., Zetterberg H., Vanmechelen E., Vanderstichele H., Andreasson U., Londos E., Wallin A., Minthon L., and Blennow K. Evaluation of plasma Abeta(40) and Abeta(42) as predictors of conversion to Alzheimer's disease in patients with mild cognitive impairment. Neurobiol. Aging (2008) doi:10.1016/j.neurobiolaging.2008.03.027
    • (2008) Neurobiol. Aging
    • Hansson, O.1    Zetterberg, H.2    Vanmechelen, E.3    Vanderstichele, H.4    Andreasson, U.5    Londos, E.6    Wallin, A.7    Minthon, L.8    Blennow, K.9
  • 35
    • 41749092079 scopus 로고    scopus 로고
    • Plasma biomarkers of Alzheimer's disease
    • Kawarabayashi T., and Shoji M. Plasma biomarkers of Alzheimer's disease. Curr. Opin. Psychiatry 21 (2008) 260-267
    • (2008) Curr. Opin. Psychiatry , vol.21 , pp. 260-267
    • Kawarabayashi, T.1    Shoji, M.2
  • 36
    • 34447303785 scopus 로고    scopus 로고
    • Alzheimer's disease and mild cognitive impairment
    • v
    • Kelley, B.J., Petersen, R.C., 2007. Alzheimer's disease and mild cognitive impairment. Neurol Clin. 25, 577-609, v.
    • (2007) Neurol Clin , vol.25 , pp. 577-609
    • Kelley, B.J.1    Petersen, R.C.2
  • 37
    • 47549105901 scopus 로고    scopus 로고
    • Alzheimer's disease, amnestic mild cognitive impairment, and age-associated memory impairment: current understanding and progress toward integrative prevention
    • Kidd P.M. Alzheimer's disease, amnestic mild cognitive impairment, and age-associated memory impairment: current understanding and progress toward integrative prevention. Altern. Med. Rev. 13 (2008) 85-115
    • (2008) Altern. Med. Rev. , vol.13 , pp. 85-115
    • Kidd, P.M.1
  • 38
    • 0035957222 scopus 로고    scopus 로고
    • Apolipoprotein A-I directly interacts with amyloid precursor protein and inhibits A beta aggregation and toxicity
    • Koldamova R.P., Letterou I.M., Lefterova M.I., and Lazo J.S. Apolipoprotein A-I directly interacts with amyloid precursor protein and inhibits A beta aggregation and toxicity. Biochemistry 40 (2001) 3553-3560
    • (2001) Biochemistry , vol.40 , pp. 3553-3560
    • Koldamova, R.P.1    Letterou, I.M.2    Lefterova, M.I.3    Lazo, J.S.4
  • 39
    • 58149102031 scopus 로고    scopus 로고
    • Cerebrospinal fluid, serum and plasma protein oxidation in Alzheimer's disease
    • Korolainen M.A., and Pirttila T. Cerebrospinal fluid, serum and plasma protein oxidation in Alzheimer's disease. Acta Neurol. Scand. 119 (2009) 32-38
    • (2009) Acta Neurol. Scand. , vol.119 , pp. 32-38
    • Korolainen, M.A.1    Pirttila, T.2
  • 43
    • 38449091610 scopus 로고    scopus 로고
    • Proteomics analysis of plasma for potential biomarkers in the diagnosis of Alzheimer's disease
    • Liao P.-c., Yu L., Kuo C.-C., Lin C., and Kuo Y.-M. Proteomics analysis of plasma for potential biomarkers in the diagnosis of Alzheimer's disease. Proteomics - Clinical Applications 1 (2007) 506-512
    • (2007) Proteomics - Clinical Applications , vol.1 , pp. 506-512
    • Liao, P.-c.1    Yu, L.2    Kuo, C.-C.3    Lin, C.4    Kuo, Y.-M.5
  • 45
    • 45149096784 scopus 로고    scopus 로고
    • Plasma amyloid beta-protein and C-reactive protein in relation to the rate of progression of Alzheimer disease
    • Locascio J.J., Fukumoto H., Yap L., Bottiglieri T., Growdon J.H., Hyman B.T., and Irizarry M.C. Plasma amyloid beta-protein and C-reactive protein in relation to the rate of progression of Alzheimer disease. Arch. Neurol. 65 (2008) 776-785
    • (2008) Arch. Neurol. , vol.65 , pp. 776-785
    • Locascio, J.J.1    Fukumoto, H.2    Yap, L.3    Bottiglieri, T.4    Growdon, J.H.5    Hyman, B.T.6    Irizarry, M.C.7
  • 48
    • 34648859471 scopus 로고    scopus 로고
    • Oxidative damage in mild cognitive impairment and early Alzheimer's disease
    • Lovell M.A., and Markesbery W.R. Oxidative damage in mild cognitive impairment and early Alzheimer's disease. J. Neurosci. Res. 85 (2007) 3036-3040
    • (2007) J. Neurosci. Res. , vol.85 , pp. 3036-3040
    • Lovell, M.A.1    Markesbery, W.R.2
  • 50
    • 0242412140 scopus 로고    scopus 로고
    • Plasma A[beta]40 and A[beta]42 and Alzheimer's disease: relation to age, mortality, and risk
    • Mayeux R., Honig L.S., Tang M.X., Manly J., Stern Y., Schupf N., and Mehta P.D. Plasma A[beta]40 and A[beta]42 and Alzheimer's disease: relation to age, mortality, and risk. Neurology 61 (2003) 1185-1190
    • (2003) Neurology , vol.61 , pp. 1185-1190
    • Mayeux, R.1    Honig, L.S.2    Tang, M.X.3    Manly, J.4    Stern, Y.5    Schupf, N.6    Mehta, P.D.7
  • 51
    • 0033975837 scopus 로고    scopus 로고
    • Plasma and cerebrospinal fluid levels of amyloid beta proteins 1-40 and 1-42 in Alzheimer disease
    • Mehta P.D., Pirttila T., Mehta S.P., Sersen E.A., Aisen P.S., and Wisniewski H.M. Plasma and cerebrospinal fluid levels of amyloid beta proteins 1-40 and 1-42 in Alzheimer disease. Arch. Neurol. 57 (2000) 100-105
    • (2000) Arch. Neurol. , vol.57 , pp. 100-105
    • Mehta, P.D.1    Pirttila, T.2    Mehta, S.P.3    Sersen, E.A.4    Aisen, P.S.5    Wisniewski, H.M.6
  • 54
    • 35348817935 scopus 로고    scopus 로고
    • F(2)-isoprostanes as biomarkers of late-onset Alzheimer's disease
    • Montine T.J., Quinn J., Kaye J., and Morrow J.D. F(2)-isoprostanes as biomarkers of late-onset Alzheimer's disease. J. Mol. Neurosci. 33 (2007) 114-119
    • (2007) J. Mol. Neurosci. , vol.33 , pp. 114-119
    • Montine, T.J.1    Quinn, J.2    Kaye, J.3    Morrow, J.D.4
  • 56
    • 40949105521 scopus 로고    scopus 로고
    • Diagnosis and treatment of dementia: 1. Risk assessment and primary prevention of Alzheimer disease
    • Patterson C., Feightner J.W., Garcia A., Hsiung G.Y., MacKnight C., and Sadovnick A.D. Diagnosis and treatment of dementia: 1. Risk assessment and primary prevention of Alzheimer disease. CMAJ 178 (2008) 548-556
    • (2008) CMAJ , vol.178 , pp. 548-556
    • Patterson, C.1    Feightner, J.W.2    Garcia, A.3    Hsiung, G.Y.4    MacKnight, C.5    Sadovnick, A.D.6
  • 57
    • 0001521232 scopus 로고
    • Ubiquitin is detected in neurofibrillary tangles and senile plaque neurites of Alzheimer disease brains
    • Perry G., Friedman R., Shaw G., and Chau V. Ubiquitin is detected in neurofibrillary tangles and senile plaque neurites of Alzheimer disease brains. Proc. Natl. Acad. Sci. U. S. A. 84 (1987) 3033-3036
    • (1987) Proc. Natl. Acad. Sci. U. S. A. , vol.84 , pp. 3033-3036
    • Perry, G.1    Friedman, R.2    Shaw, G.3    Chau, V.4
  • 60
    • 33748463935 scopus 로고    scopus 로고
    • Causes and diagnosis of Alzheimer's disease: a proteomics approach
    • Poljak A., Sachdev P., and Smythe G.A. Causes and diagnosis of Alzheimer's disease: a proteomics approach. Current Proteomics (2006) 81-112
    • (2006) Current Proteomics , pp. 81-112
    • Poljak, A.1    Sachdev, P.2    Smythe, G.A.3
  • 61
    • 33644877175 scopus 로고    scopus 로고
    • Selective reductions in plasma Abeta 1-42 in healthy elderly subjects during longitudinal follow-up: a preliminary report
    • Pomara N., Willoughby L.M., Sidtis J.J., and Mehta P.D. Selective reductions in plasma Abeta 1-42 in healthy elderly subjects during longitudinal follow-up: a preliminary report. Am. J. Geriatr. Psychiatry 13 (2005) 914-917
    • (2005) Am. J. Geriatr. Psychiatry , vol.13 , pp. 914-917
    • Pomara, N.1    Willoughby, L.M.2    Sidtis, J.J.3    Mehta, P.D.4
  • 63
    • 0028206262 scopus 로고
    • The serpin superfamily of proteinase inhibitors: structure, function, and regulation
    • Potempa J., Korzus E., and Travis J. The serpin superfamily of proteinase inhibitors: structure, function, and regulation. J. Biol. Chem. 269 (1994) 15957-15960
    • (1994) J. Biol. Chem. , vol.269 , pp. 15957-15960
    • Potempa, J.1    Korzus, E.2    Travis, J.3
  • 64
    • 13644249114 scopus 로고    scopus 로고
    • Peripheral biomarkers of oxidative damage in Alzheimer's disease: the road ahead
    • Pratico D. Peripheral biomarkers of oxidative damage in Alzheimer's disease: the road ahead. Neurobiol. Aging 26 (2005) 581-583
    • (2005) Neurobiol. Aging , vol.26 , pp. 581-583
    • Pratico, D.1
  • 65
    • 0033762711 scopus 로고    scopus 로고
    • Increased 8,12-iso-iPF2alpha-VI in Alzheimer's disease: correlation of a noninvasive index of lipid peroxidation with disease severity
    • Pratico D., Clark C.M., Lee V.M., Trojanowski J.Q., Rokach J., and FitzGerald G.A. Increased 8,12-iso-iPF2alpha-VI in Alzheimer's disease: correlation of a noninvasive index of lipid peroxidation with disease severity. Ann. Neurol. 48 (2000) 809-812
    • (2000) Ann. Neurol. , vol.48 , pp. 809-812
    • Pratico, D.1    Clark, C.M.2    Lee, V.M.3    Trojanowski, J.Q.4    Rokach, J.5    FitzGerald, G.A.6
  • 66
    • 0036284936 scopus 로고    scopus 로고
    • Increase of brain oxidative stress in mild cognitive impairment: a possible predictor of Alzheimer disease
    • Pratico D., Clark C.M., Liun F., Rokach J., Lee V.Y., and Trojanowski J.Q. Increase of brain oxidative stress in mild cognitive impairment: a possible predictor of Alzheimer disease. Arch. Neurol. 59 (2002) 972-976
    • (2002) Arch. Neurol. , vol.59 , pp. 972-976
    • Pratico, D.1    Clark, C.M.2    Liun, F.3    Rokach, J.4    Lee, V.Y.5    Trojanowski, J.Q.6
  • 71
    • 36448953140 scopus 로고    scopus 로고
    • Importance of subtle amnestic and nonamnestic deficits in mild cognitive impairment: prognosis and conversion to dementia
    • Rountree S.D., Waring S.C., Chan W.C., Lupo P.J., Darby E.J., and Doody R.S. Importance of subtle amnestic and nonamnestic deficits in mild cognitive impairment: prognosis and conversion to dementia. Dement. Geriatr. Cogn. Disord. 24 (2007) 476-482
    • (2007) Dement. Geriatr. Cogn. Disord. , vol.24 , pp. 476-482
    • Rountree, S.D.1    Waring, S.C.2    Chan, W.C.3    Lupo, P.J.4    Darby, E.J.5    Doody, R.S.6
  • 75
    • 0036321773 scopus 로고    scopus 로고
    • Early inflammation and dementia: a 25-year follow-up of the Honolulu-Asia Aging Study
    • Schmidt R., Schmidt H., Curb J.D., Masaki K., White L.R., and Launer L.J. Early inflammation and dementia: a 25-year follow-up of the Honolulu-Asia Aging Study. Ann. Neurol. 52 (2002) 168-174
    • (2002) Ann. Neurol. , vol.52 , pp. 168-174
    • Schmidt, R.1    Schmidt, H.2    Curb, J.D.3    Masaki, K.4    White, L.R.5    Launer, L.J.6
  • 77
    • 0027382008 scopus 로고
    • Vitamin status and intake as primary determinants of homocysteinemia in an elderly population
    • Selhub J., Jacques P.F., Wilson P.W., Rush D., and Rosenberg I.H. Vitamin status and intake as primary determinants of homocysteinemia in an elderly population. JAMA 270 (1993) 2693-2698
    • (1993) JAMA , vol.270 , pp. 2693-2698
    • Selhub, J.1    Jacques, P.F.2    Wilson, P.W.3    Rush, D.4    Rosenberg, I.H.5
  • 78
    • 0028267440 scopus 로고
    • Normal and abnormal biology of the beta-amyloid precursor protein
    • Selkoe D.J. Normal and abnormal biology of the beta-amyloid precursor protein. Annu. Rev. Neurosci. 17 (1994) 489-517
    • (1994) Annu. Rev. Neurosci. , vol.17 , pp. 489-517
    • Selkoe, D.J.1
  • 79
    • 0028123071 scopus 로고
    • Alzheimer's disease: a central role for amyloid
    • Selkoe D.J. Alzheimer's disease: a central role for amyloid. J. Neuropathol. Exp. Neurol. 53 (1994) 438-447
    • (1994) J. Neuropathol. Exp. Neurol. , vol.53 , pp. 438-447
    • Selkoe, D.J.1
  • 80
    • 33747391975 scopus 로고    scopus 로고
    • Elevated plasma homocysteine levels: risk factor or risk marker for the development of dementia and Alzheimer's disease?
    • Seshadri S. Elevated plasma homocysteine levels: risk factor or risk marker for the development of dementia and Alzheimer's disease?. J. Alzheimers Dis. 9 (2006) 393-398
    • (2006) J. Alzheimers Dis. , vol.9 , pp. 393-398
    • Seshadri, S.1
  • 82
    • 44549087658 scopus 로고    scopus 로고
    • Structural and quantitative comparison of cerebrospinal fluid glycoproteins in Alzheimer's disease patients and healthy individuals
    • Sihlbom C., Davidsson P., Sjogren M., Wahlund L.O., and Nilsson C.L. Structural and quantitative comparison of cerebrospinal fluid glycoproteins in Alzheimer's disease patients and healthy individuals. Neurochem. Res. 33 (2008) 1332-1340
    • (2008) Neurochem. Res. , vol.33 , pp. 1332-1340
    • Sihlbom, C.1    Davidsson, P.2    Sjogren, M.3    Wahlund, L.O.4    Nilsson, C.L.5
  • 83
    • 33947287762 scopus 로고    scopus 로고
    • Novel panel of cerebrospinal fluid biomarkers for the prediction of progression to Alzheimer dementia in patients with mild cognitive impairment
    • Simonsen A.H., McGuire J., Hansson O., Zetterberg H., Podust V.N., Davies H.A., Waldemar G., Minthon L., and Blennow K. Novel panel of cerebrospinal fluid biomarkers for the prediction of progression to Alzheimer dementia in patients with mild cognitive impairment. Arch. Neurol. 64 (2007) 366-370
    • (2007) Arch. Neurol. , vol.64 , pp. 366-370
    • Simonsen, A.H.1    McGuire, J.2    Hansson, O.3    Zetterberg, H.4    Podust, V.N.5    Davies, H.A.6    Waldemar, G.7    Minthon, L.8    Blennow, K.9
  • 84
    • 0036085791 scopus 로고    scopus 로고
    • Sodium valproate in the treatment of aggressive behavior in patients with dementia-a randomized placebo controlled clinical trial
    • Sival R.C., Haffmans P.M., Jansen P.A., Duursma S.A., and Eikelenboom P. Sodium valproate in the treatment of aggressive behavior in patients with dementia-a randomized placebo controlled clinical trial. Int. J. Geriatr. Psychiatry 17 (2002) 579-585
    • (2002) Int. J. Geriatr. Psychiatry , vol.17 , pp. 579-585
    • Sival, R.C.1    Haffmans, P.M.2    Jansen, P.A.3    Duursma, S.A.4    Eikelenboom, P.5
  • 87
    • 0030066467 scopus 로고    scopus 로고
    • Linguistic ability in early life and cognitive function and Alzheimer's disease in late life. Findings from the Nun Study
    • Snowdon D.A., Kemper S.J., Mortimer J.A., Greiner L.H., Wekstein D.R., and Markesbery W.R. Linguistic ability in early life and cognitive function and Alzheimer's disease in late life. Findings from the Nun Study. JAMA 275 (1996) 528-532
    • (1996) JAMA , vol.275 , pp. 528-532
    • Snowdon, D.A.1    Kemper, S.J.2    Mortimer, J.A.3    Greiner, L.H.4    Wekstein, D.R.5    Markesbery, W.R.6
  • 90
    • 33644664451 scopus 로고    scopus 로고
    • The effect of the APOE polymorphism on HDL-C concentrations depends on the cholesterol ester transfer protein gene variation in a Southern European population
    • Sorli J.V., Corella D., Frances F., Ramirez J.B., Gonzalez J.I., Guillen M., and Portoles O. The effect of the APOE polymorphism on HDL-C concentrations depends on the cholesterol ester transfer protein gene variation in a Southern European population. Clin. Chim. Acta 366 (2006) 196-203
    • (2006) Clin. Chim. Acta , vol.366 , pp. 196-203
    • Sorli, J.V.1    Corella, D.2    Frances, F.3    Ramirez, J.B.4    Gonzalez, J.I.5    Guillen, M.6    Portoles, O.7
  • 91
    • 0034734786 scopus 로고    scopus 로고
    • Detection of complement alternative pathway mRNA and proteins in the Alzheimer's disease brain
    • Strohmeyer R., Shen Y., and Rogers J. Detection of complement alternative pathway mRNA and proteins in the Alzheimer's disease brain. Brain Res. Mol. Brain Res. 81 (2000) 7-18
    • (2000) Brain Res. Mol. Brain Res. , vol.81 , pp. 7-18
    • Strohmeyer, R.1    Shen, Y.2    Rogers, J.3
  • 94
    • 45249102463 scopus 로고    scopus 로고
    • Biomarkers of mild cognitive impairment and Alzheimer's disease
    • Tang B.L., and Kumar R. Biomarkers of mild cognitive impairment and Alzheimer's disease. Ann. Acad. Med. Singapore 37 (2008) 406-410
    • (2008) Ann. Acad. Med. Singapore , vol.37 , pp. 406-410
    • Tang, B.L.1    Kumar, R.2
  • 96
    • 58549087156 scopus 로고    scopus 로고
    • Proteome-based identification of plasma proteins associated with hippocampal metabolism in early Alzheimer's disease
    • Thambisetty M., Hye A., Foy C., Daly E., Glover A., Cooper A., Simmons A., Murphy D., and Lovestone S. Proteome-based identification of plasma proteins associated with hippocampal metabolism in early Alzheimer's disease. J. Neurol. 255 (2008) 1712-1720
    • (2008) J. Neurol. , vol.255 , pp. 1712-1720
    • Thambisetty, M.1    Hye, A.2    Foy, C.3    Daly, E.4    Glover, A.5    Cooper, A.6    Simmons, A.7    Murphy, D.8    Lovestone, S.9
  • 97
    • 27244455440 scopus 로고    scopus 로고
    • High homocysteine and low B vitamins predict cognitive decline in aging men: the Veterans Affairs Normative Aging Study
    • Tucker K.L., Qiao N., Scott T., Rosenberg I., and Spiro III A. High homocysteine and low B vitamins predict cognitive decline in aging men: the Veterans Affairs Normative Aging Study. Am. J. Clin. Nutr. 82 (2005) 627-635
    • (2005) Am. J. Clin. Nutr. , vol.82 , pp. 627-635
    • Tucker, K.L.1    Qiao, N.2    Scott, T.3    Rosenberg, I.4    Spiro III, A.5
  • 99
    • 33745959062 scopus 로고    scopus 로고
    • Plasma Abeta(1-40) and Abeta(1-42) and the risk of dementia: a prospective case-cohort study
    • van Oijen M., Hofman A., Soares H.D., Koudstaal P.J., and Breteler M.M. Plasma Abeta(1-40) and Abeta(1-42) and the risk of dementia: a prospective case-cohort study. Lancet Neurol. 5 (2006) 655-660
    • (2006) Lancet Neurol. , vol.5 , pp. 655-660
    • van Oijen, M.1    Hofman, A.2    Soares, H.D.3    Koudstaal, P.J.4    Breteler, M.M.5
  • 100
    • 0038417096 scopus 로고    scopus 로고
    • Amyloid beta plaque-associated proteins C1q and SAP enhance the Abeta1-42 peptide-induced cytokine secretion by adult human microglia in vitro
    • Veerhuis R., Van Breemen M.J., Hoozemans J.M., Morbin M., Ouladhadj J., Tagliavini F., and Eikelenboom P. Amyloid beta plaque-associated proteins C1q and SAP enhance the Abeta1-42 peptide-induced cytokine secretion by adult human microglia in vitro. Acta Neuropathol. 105 (2003) 135-144
    • (2003) Acta Neuropathol. , vol.105 , pp. 135-144
    • Veerhuis, R.1    Van Breemen, M.J.2    Hoozemans, J.M.3    Morbin, M.4    Ouladhadj, J.5    Tagliavini, F.6    Eikelenboom, P.7
  • 103
    • 0034704261 scopus 로고    scopus 로고
    • Human neurons generate C-reactive protein and amyloid P: upregulation in Alzheimer's disease
    • Yasojima K., Schwab C., McGeer E.G., and McGeer P.L. Human neurons generate C-reactive protein and amyloid P: upregulation in Alzheimer's disease. Brain Res. 887 (2000) 80-89
    • (2000) Brain Res. , vol.887 , pp. 80-89
    • Yasojima, K.1    Schwab, C.2    McGeer, E.G.3    McGeer, P.L.4
  • 104
    • 0028945660 scopus 로고
    • Evidence that A beta 42 is the real culprit in Alzheimer's disease
    • Younkin S.G. Evidence that A beta 42 is the real culprit in Alzheimer's disease. Ann. Neurol. 37 (1995) 287-288
    • (1995) Ann. Neurol. , vol.37 , pp. 287-288
    • Younkin, S.G.1
  • 105
    • 0242440004 scopus 로고    scopus 로고
    • Aberrant profiles of native and oxidized glycoproteins in Alzheimer plasma
    • Yu H.L., Chertkow H.M., Bergman H., and Schipper H.M. Aberrant profiles of native and oxidized glycoproteins in Alzheimer plasma. Proteomics 3 (2003) 2240-2248
    • (2003) Proteomics , vol.3 , pp. 2240-2248
    • Yu, H.L.1    Chertkow, H.M.2    Bergman, H.3    Schipper, H.M.4
  • 107
    • 2542475986 scopus 로고    scopus 로고
    • Clearing amyloid through the blood-brain barrier
    • Zlokovic B.V. Clearing amyloid through the blood-brain barrier. J. Neurochem. 89 (2004) 807-811
    • (2004) J. Neurochem. , vol.89 , pp. 807-811
    • Zlokovic, B.V.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.