-
1
-
-
40849139208
-
Epigenetics in cancer
-
Esteller M. Epigenetics in cancer. N Engl J Med 2008; 358:1148-1159.
-
(2008)
N Engl J Med
, vol.358
, pp. 1148-1159
-
-
Esteller, M.1
-
2
-
-
18344390653
-
DNMT1 and DNMT3b cooperate to silence genes in human cancer cells
-
Rhee I, Bachman KE, Park BH, et al. DNMT1 and DNMT3b cooperate to silence genes in human cancer cells. Nature 2002; 416:552-556.
-
(2002)
Nature
, vol.416
, pp. 552-556
-
-
Rhee, I.1
Bachman, K.E.2
Park, B.H.3
-
3
-
-
36549053542
-
Urothelial carcinomas arising in arsenic-contaminated areas are associated with hypermethylation of the gene promoter of the death-associated protein kinase
-
Chen WT, Hung WC, Kang WY, Huang YC, Chai CY. Urothelial carcinomas arising in arsenic-contaminated areas are associated with hypermethylation of the gene promoter of the death-associated protein kinase. Histopathology 2007; 51:785-792.
-
(2007)
Histopathology
, vol.51
, pp. 785-792
-
-
Chen, W.T.1
Hung, W.C.2
Kang, W.Y.3
Huang, Y.C.4
Chai, C.Y.5
-
4
-
-
33748470485
-
Genetic and epigenetic biomarkers in cancer diagnosis and identifying high risk populations
-
Verma M, Manne U. Genetic and epigenetic biomarkers in cancer diagnosis and identifying high risk populations. Crit Rev Oncol Hematol 2006; 60:9-18.
-
(2006)
Crit Rev Oncol Hematol
, vol.60
, pp. 9-18
-
-
Verma, M.1
Manne, U.2
-
6
-
-
0036900330
-
Epigenetics in cancer: implications for early detection and prevention
-
Verma M, Srivastava S. Epigenetics in cancer: implications for early detection and prevention. Lancet Oncol 2002; 3:755-763.
-
(2002)
Lancet Oncol
, vol.3
, pp. 755-763
-
-
Verma, M.1
Srivastava, S.2
-
7
-
-
33947315736
-
Cancer epigenomics: DNA methylomes and histone-modification maps
-
Esteller M. Cancer epigenomics: DNA methylomes and histone-modification maps. Nat Rev Genet 2007; 8:286-298.
-
(2007)
Nat Rev Genet
, vol.8
, pp. 286-298
-
-
Esteller, M.1
-
8
-
-
1042278765
-
The history of cancer epigenetics
-
Feinberg AP, Tycko B. The history of cancer epigenetics. Nat Rev Cancer 2004; 4:143-153.
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 143-153
-
-
Feinberg, A.P.1
Tycko, B.2
-
9
-
-
0035870280
-
Epigenetic patterns in the progression of esophageal adenocarcinoma
-
Eads CA, Lord RV, Wickramasinghe K, et al. Epigenetic patterns in the progression of esophageal adenocarcinoma. Cancer Res 2001; 61:3410-3418.
-
(2001)
Cancer Res
, vol.61
, pp. 3410-3418
-
-
Eads, C.A.1
Lord, R.V.2
Wickramasinghe, K.3
-
10
-
-
33847065486
-
The epigenomics of cancer
-
Jones PA, Baylin SB. The epigenomics of cancer. Cell 2007; 128:683-692.
-
(2007)
Cell
, vol.128
, pp. 683-692
-
-
Jones, P.A.1
Baylin, S.B.2
-
11
-
-
17444417521
-
Cancer epigenetics
-
Laird PW Cancer epigenetics. Hum Mol Genet 2005; 14 Spec No 1:R65-R76.
-
(2005)
Hum Mol Genet
, vol.14
, Issue.1
, pp. R65-R76
-
-
Laird, P.W.1
-
12
-
-
0037356285
-
Early detection and risk assessment: proceedings and recommendations from the Workshop on Epigenetics in Cancer Prevention
-
Verma M, Dunn BK, Ross S, et al. Early detection and risk assessment: proceedings and recommendations from the Workshop on Epigenetics in Cancer Prevention. Ann N Y Acad Sci 2003; 983:298-319.
-
(2003)
Ann N Y Acad Sci
, vol.983
, pp. 298-319
-
-
Verma, M.1
Dunn, B.K.2
Ross, S.3
-
13
-
-
38049170553
-
Enhanced sensitivity to IGF-II signaling links loss of imprinting of IGF2 to increased cell proliferation and tumor risk
-
Kaneda A, Wang CJ, Cheong R, et al. Enhanced sensitivity to IGF-II signaling links loss of imprinting of IGF2 to increased cell proliferation and tumor risk. Proc Natl Acad Sci USA 2007; 104:20926-20931.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 20926-20931
-
-
Kaneda, A.1
Wang, C.J.2
Cheong, R.3
-
14
-
-
37249059981
-
Computational and experimental identification of novel human imprinted genes
-
Luedi PP, Dietrich FS, Weidman JR, Bosko JM, Jirtle RL, Hartemink AJ. Computational and experimental identification of novel human imprinted genes. Genome Res 2007; 17:1723-1730.
-
(2007)
Genome Res
, vol.17
, pp. 1723-1730
-
-
Luedi, P.P.1
Dietrich, F.S.2
Weidman, J.R.3
Bosko, J.M.4
Jirtle, R.L.5
Hartemink, A.J.6
-
15
-
-
34548131197
-
Epigenetic specificity of loss of imprinting of the IGF2 gene in Wilms tumors
-
Bjornsson HT, Brown LJ, Fallin MD, et al. Epigenetic specificity of loss of imprinting of the IGF2 gene in Wilms tumors. J Natl Cancer Inst 2007; 99:1270-1273.
-
(2007)
J Natl Cancer Inst
, vol.99
, pp. 1270-1273
-
-
Bjornsson, H.T.1
Brown, L.J.2
Fallin, M.D.3
-
16
-
-
36348970734
-
Examination of IGF2 and H19 loss of imprinting in bladder cancer
-
Byun HM, Wong HL, Birnstein EA, Wolff EM, Liang G, Yang AS. Examination of IGF2 and H19 loss of imprinting in bladder cancer. Cancer Res 2007; 67:10753-10758.
-
(2007)
Cancer Res
, vol.67
, pp. 10753-10758
-
-
Byun, H.M.1
Wong, H.L.2
Birnstein, E.A.3
Wolff, E.M.4
Liang, G.5
Yang, A.S.6
-
17
-
-
34047260919
-
Imprinting may provide cancer prevention tools
-
Hede K. Imprinting may provide cancer prevention tools. J Natl Cancer Inst 2007; 99:424-426.
-
(2007)
J Natl Cancer Inst
, vol.99
, pp. 424-426
-
-
Hede, K.1
-
18
-
-
34247873111
-
The silence of genes. Is genomic imprinting the software of evolution or just a battleground for gender conflict?
-
Hunter P. The silence of genes. Is genomic imprinting the software of evolution or just a battleground for gender conflict? EMBO Rep 2007; 8:441-443.
-
(2007)
EMBO Rep
, vol.8
, pp. 441-443
-
-
Hunter, P.1
-
19
-
-
35448985442
-
The dynamic epigenome and its implications in toxicology
-
Szyf M. The dynamic epigenome and its implications in toxicology. Toxicol Sci 2007; 100:7-23.
-
(2007)
Toxicol Sci
, vol.100
, pp. 7-23
-
-
Szyf, M.1
-
20
-
-
34247487528
-
Loss of H19 imprinting in adult T-cell leukaemia/lymphoma
-
Takeuchi S, Hofmann WK, Tsukasaki K, et al. Loss of H19 imprinting in adult T-cell leukaemia/lymphoma. Br J Haematol 2007; 137:380-381.
-
(2007)
Br J Haematol
, vol.137
, pp. 380-381
-
-
Takeuchi, S.1
Hofmann, W.K.2
Tsukasaki, K.3
-
21
-
-
34548743369
-
Duplication of the paternal IGF2 allele in trisomy 11 and elevated expression levels of IGF2 mRNA in congenital mesoblastic nephroma of the cellular or mixed type
-
Watanabe N, Haruta M, Soejima H, et al. Duplication of the paternal IGF2 allele in trisomy 11 and elevated expression levels of IGF2 mRNA in congenital mesoblastic nephroma of the cellular or mixed type. Genes Chromosomes Cancer 2007; 46:929-935.
-
(2007)
Genes Chromosomes Cancer
, vol.46
, pp. 929-935
-
-
Watanabe, N.1
Haruta, M.2
Soejima, H.3
-
22
-
-
35548941189
-
Epigenetic epidemiology of the developmental origins hypothesis
-
Waterland RA, Michels KB. Epigenetic epidemiology of the developmental origins hypothesis. Annu Rev Nutr 2007; 27:363-388.
-
(2007)
Annu Rev Nutr
, vol.27
, pp. 363-388
-
-
Waterland, R.A.1
Michels, K.B.2
-
23
-
-
34948830291
-
High-throughput methylation profiling by MCA coupled to CpG island microarray
-
Estecio MR, Yan PS, Ibrahim AE, et al. High-throughput methylation profiling by MCA coupled to CpG island microarray. Genome Res 2007; 17:1529-1536.
-
(2007)
Genome Res
, vol.17
, pp. 1529-1536
-
-
Estecio, M.R.1
Yan, P.S.2
Ibrahim, A.E.3
-
24
-
-
0034015947
-
K-ras mutation: early detection in molecular diagnosis and risk assessment of colorectal, pancreas, and lung cancers-a review
-
Minamoto T, Mai M, Ronai Z. K-ras mutation: early detection in molecular diagnosis and risk assessment of colorectal, pancreas, and lung cancers-a review. Cancer Detect Prev 2000; 24:1-12.
-
(2000)
Cancer Detect Prev
, vol.24
, pp. 1-12
-
-
Minamoto, T.1
Mai, M.2
Ronai, Z.3
-
25
-
-
11144356831
-
Methylation changes in faecal DNA: a marker for colorectal cancer screening?
-
Muller HM, Oberwalder M, Fiegl H, et al. Methylation changes in faecal DNA: a marker for colorectal cancer screening? Lancet 2004; 363:1283-1285.
-
(2004)
Lancet
, vol.363
, pp. 1283-1285
-
-
Muller, H.M.1
Oberwalder, M.2
Fiegl, H.3
-
26
-
-
0036157647
-
Tumor p16M is a possible marker of advanced stage in non-small cell lung cancer
-
Ng CS, Zhang J, Wan S, et al. Tumor p16M is a possible marker of advanced stage in non-small cell lung cancer. J Surg Oncol 2002; 79:101-106.
-
(2002)
J Surg Oncol
, vol.79
, pp. 101-106
-
-
Ng, C.S.1
Zhang, J.2
Wan, S.3
-
27
-
-
0032807639
-
Role of tumor markers and mutations in cells and pancreatic juice in the diagnosis of pancreatic cancer
-
Tascilar M, Caspers E, Sturm PD, Goggins M, Hruban RH, Offerhaus GJ. Role of tumor markers and mutations in cells and pancreatic juice in the diagnosis of pancreatic cancer. Ann Oncol 1999; 10(Suppl 4):107-110.
-
(1999)
Ann Oncol
, vol.10
, pp. 107-110
-
-
Tascilar, M.1
Caspers, E.2
Sturm, P.D.3
Goggins, M.4
Hruban, R.H.5
Offerhaus, G.J.6
-
28
-
-
33751320353
-
Comparison of microsatellite instability, CpG island methylation phenotype, BRAF and KRAS status in serrated polyps and traditional adenomas indicates separate pathways to distinct colorectal carcinoma end points
-
O'Brien MJ, Yang S, Mack C, et al. Comparison of microsatellite instability, CpG island methylation phenotype, BRAF and KRAS status in serrated polyps and traditional adenomas indicates separate pathways to distinct colorectal carcinoma end points. Am J Surg Pathol 2006; 30:1491-1501.
-
(2006)
Am J Surg Pathol
, vol.30
, pp. 1491-1501
-
-
O'Brien, M.J.1
Yang, S.2
Mack, C.3
-
29
-
-
42349107016
-
Genome-wide promoter analysis uncovers portions of the cancer methylome
-
Hoque MO, Kim MS, Ostrow KL, et al. Genome-wide promoter analysis uncovers portions of the cancer methylome. Cancer Res 2008; 68:2661-2670.
-
(2008)
Cancer Res
, vol.68
, pp. 2661-2670
-
-
Hoque, M.O.1
Kim, M.S.2
Ostrow, K.L.3
-
30
-
-
36049007134
-
Hypomethylation and aberrant expression of the glioma pathogenesis-related 1 gene in Wilms tumors
-
Chilukamarri L, Hancock AL, Malik S, et al. Hypomethylation and aberrant expression of the glioma pathogenesis-related 1 gene in Wilms tumors. Neoplasia 2007; 9:970-978.
-
(2007)
Neoplasia
, vol.9
, pp. 970-978
-
-
Chilukamarri, L.1
Hancock, A.L.2
Malik, S.3
-
31
-
-
36749052947
-
DNA methylation signatures within the human brain
-
Ladd-Acosta C, Pevsner J, Sabunciyan S, et al. DNA methylation signatures within the human brain. Am J Hum Genet 2007; 81:1304-1315.
-
(2007)
Am J Hum Genet
, vol.81
, pp. 1304-1315
-
-
Ladd-acosta, C.1
Pevsner, J.2
Sabunciyan, S.3
-
32
-
-
0037468143
-
Methylation status of p14ARF and p16INK4a as detected in pancreatic secretions
-
Klump B, Hsieh CJ, Nehls O, et al. Methylation status of p14ARF and p16INK4a as detected in pancreatic secretions. Br J Cancer 2003; 88:217-222.
-
(2003)
Br J Cancer
, vol.88
, pp. 217-222
-
-
Klump, B.1
Hsieh, C.J.2
Nehls, O.3
-
33
-
-
33751275546
-
Examination of a CpG island methylator phenotype and implications of methylation profiles in solid tumors
-
Marsit CJ, Houseman EA, Christensen BC, et al. Examination of a CpG island methylator phenotype and implications of methylation profiles in solid tumors. Cancer Res 2006; 66:10621-10629.
-
(2006)
Cancer Res
, vol.66
, pp. 10621-10629
-
-
Marsit, C.J.1
Houseman, E.A.2
Christensen, B.C.3
-
34
-
-
34548079728
-
Promoter hypermethylation is associated with current smoking, age, gender and survival in bladder cancer
-
Marsit CJ, Houseman EA, Schned AR, Karagas MR, Kelsey KT. Promoter hypermethylation is associated with current smoking, age, gender and survival in bladder cancer. Carcinogenesis 2007; 28:1745-1751.
-
(2007)
Carcinogenesis
, vol.28
, pp. 1745-1751
-
-
Marsit, C.J.1
Houseman, E.A.2
Schned, A.R.3
Karagas, M.R.4
Kelsey, K.T.5
-
36
-
-
0034658196
-
Differential mRNA expression of the human DNA methyltransferases (DNMTs) 1, 3a and 3b during the G(0)/G(1) to S phase transition in normal and tumor cells
-
Robertson KD, Keyomarsi K, Gonzales FA, Velicescu M, Jones PA. Differential mRNA expression of the human DNA methyltransferases (DNMTs) 1, 3a and 3b during the G(0)/G(1) to S phase transition in normal and tumor cells. Nucleic Acids Res 2000; 28:2108-2113.
-
(2000)
Nucleic Acids Res
, vol.28
, pp. 2108-2113
-
-
Robertson, K.D.1
Keyomarsi, K.2
Gonzales, F.A.3
Velicescu, M.4
Jones, P.A.5
-
37
-
-
31544467813
-
De novo CpG island methylation in human cancer cells
-
Jair KW, Bachman KE, Suzuki H, et al. De novo CpG island methylation in human cancer cells. Cancer Res 2006; 66:682-692.
-
(2006)
Cancer Res
, vol.66
, pp. 682-692
-
-
Jair, K.W.1
Bachman, K.E.2
Suzuki, H.3
-
38
-
-
33847373449
-
The role of DNA methylation in the development and progression of lung adenocarcinoma
-
Kerr KM, Galler JS, Hagen JA, Laird PW, Laird-Offringa IA. The role of DNA methylation in the development and progression of lung adenocarcinoma. Dis Markers 2007; 23:5-30.
-
(2007)
Dis Markers
, vol.23
, pp. 5-30
-
-
Kerr, K.M.1
Galler, J.S.2
Hagen, J.A.3
Laird, P.W.4
Laird-offringa, I.A.5
-
39
-
-
0038576158
-
The power and the promise of DNA methylation markers
-
Laird PW. The power and the promise of DNA methylation markers. Nat Rev Cancer 2003; 3:253-266.
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 253-266
-
-
Laird, P.W.1
-
40
-
-
33745500432
-
CpG island methylator phenotype (CIMP) of colorectal cancer is best characterised by quantitative DNA methylation analysis and prospective cohort studies
-
Ogino S, Cantor M, Kawasaki T, et al. CpG island methylator phenotype (CIMP) of colorectal cancer is best characterised by quantitative DNA methylation analysis and prospective cohort studies. Gut 2006; 55:1000-1006.
-
(2006)
Gut
, vol.55
, pp. 1000-1006
-
-
Ogino, S.1
Cantor, M.2
Kawasaki, T.3
-
41
-
-
0345701519
-
Aberrant DNA methylation in ovarian cancer: is there an epigenetic predisposition to drug response?
-
Wei SH, Brown R, Huang TH. Aberrant DNA methylation in ovarian cancer: is there an epigenetic predisposition to drug response? Ann N Y Acad Sci 2003; 983:243-250.
-
(2003)
Ann N Y Acad Sci
, vol.983
, pp. 243-250
-
-
Wei, S.H.1
Brown, R.2
Huang, T.H.3
-
42
-
-
0037455915
-
Epigenetic gene silencing in cancer initiation and progression
-
Nephew KP, Huang TH. Epigenetic gene silencing in cancer initiation and progression. Cancer Lett 2003; 190:125-133.
-
(2003)
Cancer Lett
, vol.190
, pp. 125-133
-
-
Nephew, K.P.1
Huang, T.H.2
-
43
-
-
13844320649
-
Aberrant DNA methylation as a cancer-inducing mechanism
-
Esteller M. Aberrant DNA methylation as a cancer-inducing mechanism. Annu Rev Pharmacol Toxicol 2005; 45:629-656.
-
(2005)
Annu Rev Pharmacol Toxicol
, vol.45
, pp. 629-656
-
-
Esteller, M.1
-
44
-
-
0035930097
-
Quantitation of GSTP1 methylation in non-neoplastic prostatic tissue and organ-confined prostate adenocarcinoma
-
Jeronimo C, Usadel H, Henrique R, et al. Quantitation of GSTP1 methylation in non-neoplastic prostatic tissue and organ-confined prostate adenocarcinoma. J Natl Cancer Inst 2001; 93:1747-1752.
-
(2001)
J Natl Cancer Inst
, vol.93
, pp. 1747-1752
-
-
Jeronimo, C.1
Usadel, H.2
Henrique, R.3
-
45
-
-
21344474319
-
Cloning of the hamster p16 gene 5' upstream region and its aberrant methylation patterns in pancreatic cancer
-
Hanaoka M, Shimizu K, Shigemura M, et al. Cloning of the hamster p16 gene 5' upstream region and its aberrant methylation patterns in pancreatic cancer. Biochem Biophys Res Commun 2005; 333:1249-1253.
-
(2005)
Biochem Biophys Res Commun
, vol.333
, pp. 1249-1253
-
-
Hanaoka, M.1
Shimizu, K.2
Shigemura, M.3
-
46
-
-
0842289159
-
Aberrant hypermethylation of tumor suppressor genes in pancreatic endocrine neoplasms
-
discussion 431-422
-
House MG, Herman JG, Guo MZ, et al. Aberrant hypermethylation of tumor suppressor genes in pancreatic endocrine neoplasms. Ann Surg 2003; 238;423-431; discussion 431-422.
-
(2003)
Ann Surg
, vol.238
, pp. 423-431
-
-
House, M.G.1
Herman, J.G.2
Guo, M.Z.3
-
47
-
-
38449110073
-
Detection of promoter hypermethylation in serum samples of cancer patients by methylation-specific polymerase chain reaction for tumour suppressor genes including RUNX3
-
Tan SH, Ida H, Lau QC, et al. Detection of promoter hypermethylation in serum samples of cancer patients by methylation-specific polymerase chain reaction for tumour suppressor genes including RUNX3. Oncol Rep 2007; 18:1225-1230.
-
(2007)
Oncol Rep
, vol.18
, pp. 1225-1230
-
-
Tan, S.H.1
Ida, H.2
Lau, Q.C.3
-
48
-
-
0034808413
-
Molecular detection of prostate cancer in urine by GSTP1 hypermethylation
-
Cairns P, Esteller M, Herman JG, et al. Molecular detection of prostate cancer in urine by GSTP1 hypermethylation. Clin Cancer Res 2001; 7:2727-2730.
-
(2001)
Clin Cancer Res
, vol.7
, pp. 2727-2730
-
-
Cairns, P.1
Esteller, M.2
Herman, J.G.3
-
49
-
-
33645461015
-
Discovery of novel methylation biomarkers in cervical carcinoma by global demethylation and microarray analysis
-
Sova P, Feng Q, Geiss G, et al. Discovery of novel methylation biomarkers in cervical carcinoma by global demethylation and microarray analysis. Cancer Epidemiol Biomarkers Prev 2006; 15:114-123.
-
(2006)
Cancer Epidemiol Biomarkers Prev
, vol.15
, pp. 114-123
-
-
Sova, P.1
Feng, Q.2
Geiss, G.3
-
50
-
-
34250855800
-
Promoter hypermethylation of tumor suppressor genes in urine from patients with cervical neoplasia
-
Feng Q, Hawes SE, Stern JE, et al. Promoter hypermethylation of tumor suppressor genes in urine from patients with cervical neoplasia. Cancer Epidemiol Biomarkers Prev 2007; 16:1178-1184.
-
(2007)
Cancer Epidemiol Biomarkers Prev
, vol.16
, pp. 1178-1184
-
-
Feng, Q.1
Hawes, S.E.2
Stern, J.E.3
-
51
-
-
33845926895
-
A genome-wide screen for promoter methylation in lung cancer identifies novel methylation markers for multiple malignancies
-
Shames DS, Girard L, Gao B, et al. A genome-wide screen for promoter methylation in lung cancer identifies novel methylation markers for multiple malignancies. PLoS Med 2006; 3:e486.
-
(2006)
PLoS Med
, vol.3
, pp. e486
-
-
Shames, D.S.1
Girard, L.2
Gao, B.3
-
52
-
-
33847317873
-
DNA methylation in health, disease, and cancer
-
Shames DS, Minna JD, Gazdar AF. DNA methylation in health, disease, and cancer. Curr Mol Med 2007; 7:85-102.
-
(2007)
Curr Mol Med
, vol.7
, pp. 85-102
-
-
Shames, D.S.1
Minna, J.D.2
Gazdar, A.F.3
-
53
-
-
33748040054
-
Correlation of pathologic features with CpG island methylator phenotype (CIMP) by quantitative DNA methylation analysis in colorectal carcinoma
-
Ogino S, Odze RD, Kawasaki T, et al. Correlation of pathologic features with CpG island methylator phenotype (CIMP) by quantitative DNA methylation analysis in colorectal carcinoma. Am J Surg Pathol 2006; 30:1175-1183.
-
(2006)
Am J Surg Pathol
, vol.30
, pp. 1175-1183
-
-
Ogino, S.1
Odze, R.D.2
Kawasaki, T.3
-
54
-
-
33745541234
-
CpG island methylator phenotype underlies sporadic microsatellite instability and is tightly associated with BRAF mutation in colorectal cancer
-
Weisenberger DJ, Siegmund KD, Campan M, et al. CpG island methylator phenotype underlies sporadic microsatellite instability and is tightly associated with BRAF mutation in colorectal cancer. Nat Genet 2006; 38:787-793.
-
(2006)
Nat Genet
, vol.38
, pp. 787-793
-
-
Weisenberger, D.J.1
Siegmund, K.D.2
Campan, M.3
-
55
-
-
40849124009
-
DNA methylation markers and early recurrence in stage I lung cancer
-
Brock MV, Hooker CM, Ota-Machida E, et al. DNA methylation markers and early recurrence in stage I lung cancer. N Engl J Med 2008; 358:1118-1128.
-
(2008)
N Engl J Med
, vol.358
, pp. 1118-1128
-
-
Brock, M.V.1
Hooker, C.M.2
Ota-machida, E.3
-
56
-
-
45849088842
-
Reduced T-cadherin expression and promoter methylation are associated with the development and progression of hepatocellular carcinoma
-
Yan Q, Zhang ZF, Chen XP, et al. Reduced T-cadherin expression and promoter methylation are associated with the development and progression of hepatocellular carcinoma. Int J Oncol 2008; 32:1057-1063.
-
(2008)
Int J Oncol
, vol.32
, pp. 1057-1063
-
-
Yan, Q.1
Zhang, Z.F.2
Chen, X.P.3
-
57
-
-
5144220196
-
Molecular detection of prostate cancer: a role for GSTP1 hypermethylation
-
discussion 669
-
Henrique R, Jeronimo C. Molecular detection of prostate cancer: a role for GSTP1 hypermethylation. Eur Urol 2004; 46;660-669; discussion 669.
-
(2004)
Eur Urol
, vol.46
, pp. 660-669
-
-
Henrique, R.1
Jeronimo, C.2
-
58
-
-
0034669126
-
Hypermethylated APC DNA in plasma and prognosis of patients with esophageal adenocarcinoma
-
Kawakami K, Brabender J, Lord RV, et al. Hypermethylated APC DNA in plasma and prognosis of patients with esophageal adenocarcinoma. J Natl Cancer Inst 2000; 92:1805-1811.
-
(2000)
J Natl Cancer Inst
, vol.92
, pp. 1805-1811
-
-
Kawakami, K.1
Brabender, J.2
Lord, R.V.3
-
59
-
-
0035750549
-
Thymidylate synthase gene polymorphism determines response and toxicity of 5-FU chemotherapy
-
Pullarkat ST, Stoehlmacher J, Ghaderi V, et al. Thymidylate synthase gene polymorphism determines response and toxicity of 5-FU chemotherapy. Pharmacogenomics J 2001; 1:65-70.
-
(2001)
Pharmacogenomics J
, vol.1
, pp. 65-70
-
-
Pullarkat, S.T.1
Stoehlmacher, J.2
Ghaderi, V.3
-
61
-
-
0037354509
-
Epidemiologic considerations to assess altered DNA methylation from environmental exposures in cancer
-
Moore LE, Huang WY, Chung J, Hayes RB. Epidemiologic considerations to assess altered DNA methylation from environmental exposures in cancer. Ann N Y Acad Sci 2003; 983:181-196.
-
(2003)
Ann N Y Acad Sci
, vol.983
, pp. 181-196
-
-
Moore, L.E.1
Huang, W.Y.2
Chung, J.3
Hayes, R.B.4
-
63
-
-
39349099944
-
Medical surveillance of previously asbestos-exposed workers: report of a case of lung cancer with high level of serum mesothelin
-
Guglielmi G, Ciberti A, Foddis R, et al. Medical surveillance of previously asbestos-exposed workers: report of a case of lung cancer with high level of serum mesothelin. Giornale italiano di medicina del lavoro ed ergonomia 2007; 29:345-346.
-
(2007)
Giornale italiano di medicina del lavoro ed ergonomia
, vol.29
, pp. 345-346
-
-
Guglielmi, G.1
Ciberti, A.2
Foddis, R.3
-
64
-
-
0036312569
-
Alterations of the p16(INK4) locus in human malignant mesothelial tumors
-
Hirao T, Bueno R, Chen CJ, Gordon GJ, Heilig E, Kelsey KT. Alterations of the p16(INK4) locus in human malignant mesothelial tumors. Carcinogenesis 2002; 23:1127-1130.
-
(2002)
Carcinogenesis
, vol.23
, pp. 1127-1130
-
-
Hirao, T.1
Bueno, R.2
Chen, C.J.3
Gordon, G.J.4
Heilig, E.5
Kelsey, K.T.6
-
65
-
-
39749171775
-
Environmental epigenomics in human health and disease
-
Dolinoy DC, Jirtle RL. Environmental epigenomics in human health and disease. Environ Mol Mutagen 2008; 49:4-8.
-
(2008)
Environ Mol Mutagen
, vol.49
, pp. 4-8
-
-
Dolinoy, D.C.1
Jirtle, R.L.2
-
66
-
-
33645521023
-
Promoter hypermethylation of multiple genes in sputum precedes lung cancer incidence in a high-risk cohort
-
Belinsky SA, Liechty KC, Gentry FD, et al. Promoter hypermethylation of multiple genes in sputum precedes lung cancer incidence in a high-risk cohort. Cancer Res 2006; 66:3338-3344.
-
(2006)
Cancer Res
, vol.66
, pp. 3338-3344
-
-
Belinsky, S.A.1
Liechty, K.C.2
Gentry, F.D.3
-
67
-
-
8644243891
-
Conserved methylation patterns of human papillomavirus type 16 DNA in asymptomatic infection and cervical neoplasia
-
Kalantari M, Calleja-Macias IE, Tewari D, et al. Conserved methylation patterns of human papillomavirus type 16 DNA in asymptomatic infection and cervical neoplasia. J Virol 2004; 78:12762-12772.
-
(2004)
J Virol
, vol.78
, pp. 12762-12772
-
-
Kalantari, M.1
Calleja-macias, I.E.2
Tewari, D.3
-
68
-
-
0242661842
-
Methylation patterns of papillomavirus DNA, its influence on E2 function, and implications in viral infection
-
Kim K, Garner-Hamrick PA, Fisher C, Lee D, Lambert PF. Methylation patterns of papillomavirus DNA, its influence on E2 function, and implications in viral infection. J Virol 2003; 77:12450-12459.
-
(2003)
J Virol
, vol.77
, pp. 12450-12459
-
-
Kim, K.1
Garner-hamrick, P.A.2
Fisher, C.3
Lee, D.4
Lambert, P.F.5
-
69
-
-
2542429289
-
Analysis of aberrant DNA methylation and human papillomavirus DNA in cervicovaginal specimens to detect invasive cervical cancer and its precursors
-
Widschwendter A, Gattringer C, Ivarsson L, et al. Analysis of aberrant DNA methylation and human papillomavirus DNA in cervicovaginal specimens to detect invasive cervical cancer and its precursors. Clin Cancer Res 2004; 10:3396-3400.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 3396-3400
-
-
Widschwendter, A.1
Gattringer, C.2
Ivarsson, L.3
-
70
-
-
33845457109
-
p73 gene promoter methylation in Epstein-Barr virus-associated gastric carcinoma
-
Ushiku T, Chong JM, Uozaki H, et al. p73 gene promoter methylation in Epstein-Barr virus-associated gastric carcinoma. Int J Cancer 2007; 120:60-66.
-
(2007)
Int J Cancer
, vol.120
, pp. 60-66
-
-
Ushiku, T.1
Chong, J.M.2
Uozaki, H.3
-
71
-
-
33748098027
-
Epigenotypes of latent herpesvirus genomes
-
Minarovits J. Epigenotypes of latent herpesvirus genomes. Curr Top Microbiol Immunol 2006; 310:61-80.
-
(2006)
Curr Top Microbiol Immunol
, vol.310
, pp. 61-80
-
-
Minarovits, J.1
-
72
-
-
35448960424
-
Helicobacter pylori and epigenetic mechanisms underlying gastric carcinogenesis
-
Nardone G, Compare D, De Colibus P, de Nucci G, Rocco A. Helicobacter pylori and epigenetic mechanisms underlying gastric carcinogenesis. Dig Dis 2007; 25:225-229.
-
(2007)
Dig Dis
, vol.25
, pp. 225-229
-
-
Nardone, G.1
Compare, D.2
De Colibus, P.3
de Nucci, G.4
Rocco, A.5
-
73
-
-
44649172694
-
KSHV LANA inhibits TGF-ObetaO signaling through epigenetic silencing of the TGF-ObetaO type II receptor
-
Di Bartolo DL, Cannon M, Liu YF, et al. KSHV LANA inhibits TGF-ObetaO signaling through epigenetic silencing of the TGF-ObetaO type II receptor. Blood 2008; 111:4731-4740.
-
(2008)
Blood
, vol.111
, pp. 4731-4740
-
-
Di Bartolo, D.L.1
Cannon, M.2
Liu, Y.F.3
-
75
-
-
0037356309
-
Viral genes and methylation
-
Verma M. Viral genes and methylation. Ann N Y Acad Sci 2003; 983:170-180.
-
(2003)
Ann N Y Acad Sci
, vol.983
, pp. 170-180
-
-
Verma, M.1
-
76
-
-
33846796029
-
Zebularine reactivates silenced E-cadherin but unlike 5-Azacytidine does not induce switching from latent to lytic Epstein-Barr virus infection in Burkitt's lymphoma Akata cells
-
Rao SP, Rechsteiner MP, Berger C, Sigrist JA, Nadal D, Bernasconi M. Zebularine reactivates silenced E-cadherin but unlike 5-Azacytidine does not induce switching from latent to lytic Epstein-Barr virus infection in Burkitt's lymphoma Akata cells. Mol Cancer 2007; 6:3.
-
(2007)
Mol Cancer
, vol.6
, pp. 3
-
-
Rao, S.P.1
Rechsteiner, M.P.2
Berger, C.3
Sigrist, J.A.4
Nadal, D.5
Bernasconi, M.6
-
77
-
-
32944459562
-
High levels of aberrant DNA methylation in Helicobacter pylori-infected gastric mucosae and its possible association with gastric cancer risk
-
Maekita T, Nakazawa K, Mihara M, et al. High levels of aberrant DNA methylation in Helicobacter pylori-infected gastric mucosae and its possible association with gastric cancer risk. Clin Cancer Res 2006; 12:989-995.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 989-995
-
-
Maekita, T.1
Nakazawa, K.2
Mihara, M.3
-
78
-
-
34250812150
-
Aberrant DNA methylation in non-neoplastic gastric mucosa of H. Pylori infected patients and effect of eradication
-
Perri F, Cotugno R, Piepoli A, et al. Aberrant DNA methylation in non-neoplastic gastric mucosa of H. Pylori infected patients and effect of eradication. Am J Gastroenterol 2007; 102:1361-1371.
-
(2007)
Am J Gastroenterol
, vol.102
, pp. 1361-1371
-
-
Perri, F.1
Cotugno, R.2
Piepoli, A.3
-
79
-
-
34447520629
-
Genomic methylation: a tool for typing Helicobacter pylori isolates
-
Vale FF, Vitor JM. Genomic methylation: a tool for typing Helicobacter pylori isolates. Appl Environ Microbiol 2007; 73:4243-4249.
-
(2007)
Appl Environ Microbiol
, vol.73
, pp. 4243-4249
-
-
Vale, F.F.1
Vitor, J.M.2
-
80
-
-
35148830823
-
Promoter hypermethylation of multiple genes in gastric lymphoma
-
Huang Q, Su X, Ai L, Li M, Fan CY, Weiss LM. Promoter hypermethylation of multiple genes in gastric lymphoma. Leuk Lymphoma 2007; 48:1988-1996.
-
(2007)
Leuk Lymphoma
, vol.48
, pp. 1988-1996
-
-
Huang, Q.1
Su, X.2
Ai, L.3
Li, M.4
Fan, C.Y.5
Weiss, L.M.6
-
81
-
-
33144488275
-
Post-weaning diet affects genomic imprinting at the insulin-like growth factor 2 (Igf2) locus
-
Waterland RA, Lin JR, Smith CA, Jirtle RL. Post-weaning diet affects genomic imprinting at the insulin-like growth factor 2 (Igf2) locus. Hum Mol Genet 2006; 15:705-716.
-
(2006)
Hum Mol Genet
, vol.15
, pp. 705-716
-
-
Waterland, R.A.1
Lin, J.R.2
Smith, C.A.3
Jirtle, R.L.4
-
82
-
-
33751512673
-
Transgenerational epigenetic imprinting of the male germline by endocrine disruptor exposure during gonadal sex determination
-
Chang HS, Anway MD, Rekow SS, Skinner MK. Transgenerational epigenetic imprinting of the male germline by endocrine disruptor exposure during gonadal sex determination. Endocrinology 2006; 147:5524-5541.
-
(2006)
Endocrinology
, vol.147
, pp. 5524-5541
-
-
Chang, H.S.1
Anway, M.D.2
Rekow, S.S.3
Skinner, M.K.4
-
83
-
-
34347247712
-
Transgenerational epigenetic imprints on mate preference
-
Crews D, Gore AC, Hsu TS, et al. Transgenerational epigenetic imprints on mate preference. Proc Natl Acad Sci USA 2007; 104:5942-5946.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 5942-5946
-
-
Crews, D.1
Gore, A.C.2
Hsu, T.S.3
-
84
-
-
32244433720
-
Seminiferous cord formation and germ-cell programming: epigenetic transgenerational actions of endocrine disruptors
-
Skinner MK, Anway MD. Seminiferous cord formation and germ-cell programming: epigenetic transgenerational actions of endocrine disruptors. Ann N Y Acad Sci 2005; 1061:18-32.
-
(2005)
Ann N Y Acad Sci
, vol.1061
, pp. 18-32
-
-
Skinner, M.K.1
Anway, M.D.2
-
85
-
-
33751528552
-
Endocrine disruptors: do family lines carry an epigenetic record of previous generations' exposures?
-
Zoeller RT. Endocrine disruptors: do family lines carry an epigenetic record of previous generations' exposures? Endocrinology 2006; 147:5513-5514.
-
(2006)
Endocrinology
, vol.147
, pp. 5513-5514
-
-
Zoeller, R.T.1
-
86
-
-
39749192000
-
Analysis of 5-methylcytosine in DNA of breast and colon cancer tissues
-
Barciszewska AM, Murawa D, Gawronska I, Murawa P, Nowak S, Barciszewska MZ. Analysis of 5-methylcytosine in DNA of breast and colon cancer tissues. IUBMB Life 2007; 59:765-770.
-
(2007)
IUBMB Life
, vol.59
, pp. 765-770
-
-
Barciszewska, A.M.1
Murawa, D.2
Gawronska, I.3
Murawa, P.4
Nowak, S.5
Barciszewska, M.Z.6
-
87
-
-
38749121383
-
Array-based multiplex analysis of DNA methylation in breast cancer tissues
-
Melnikov AA, Scholtens DM, Wiley EL, Khan SA, Levenson VV. Array-based multiplex analysis of DNA methylation in breast cancer tissues. J Mol Diagn 2008; 10:93-101.
-
(2008)
J Mol Diagn
, vol.10
, pp. 93-101
-
-
Melnikov, A.A.1
Scholtens, D.M.2
Wiley, E.L.3
Khan, S.A.4
Levenson, V.V.5
-
88
-
-
39749184105
-
Methylation status of breast cancer resistance protein detected by methylation-specific polymerase chain reaction analysis is correlated inversely with its expression in drug-resistant lung cancer cells
-
Nakano H, Nakamura Y, Soda H, et al. Methylation status of breast cancer resistance protein detected by methylation-specific polymerase chain reaction analysis is correlated inversely with its expression in drug-resistant lung cancer cells. Cancer 2008; 112 (5):1122-1130.
-
(2008)
Cancer
, vol.112
, Issue.5
, pp. 1122-1130
-
-
Nakano, H.1
Nakamura, Y.2
Soda, H.3
-
89
-
-
44449175595
-
Identification of novel high-frequency DNA methylation changes in breast cancer
-
Ordway JM, Budiman MA, Korshunova Y, et al. Identification of novel high-frequency DNA methylation changes in breast cancer. PLoS ONE 2007; 2:e1314.
-
(2007)
PLoS ONE
, vol.2
, pp. e1314
-
-
Ordway, J.M.1
Budiman, M.A.2
Korshunova, Y.3
-
90
-
-
34147158249
-
Detection of RASSF1A and RARbeta hypermethylation in serum DNA from breast cancer patients
-
Shukla S, Mirza S, Sharma G, Parshad R, Gupta SD, Ralhan R. Detection of RASSF1A and RARbeta hypermethylation in serum DNA from breast cancer patients. Epigenetics 2006; 1:88-93.
-
(2006)
Epigenetics
, vol.1
, pp. 88-93
-
-
Shukla, S.1
Mirza, S.2
Sharma, G.3
Parshad, R.4
Gupta, S.D.5
Ralhan, R.6
-
91
-
-
36849037857
-
Epigenetic regulation as a new target for breast cancer therapy
-
Stearns V, Zhou Q, Davidson NE. Epigenetic regulation as a new target for breast cancer therapy. Cancer Invest 2007; 25:659-665.
-
(2007)
Cancer Invest
, vol.25
, pp. 659-665
-
-
Stearns, V.1
Zhou, Q.2
Davidson, N.E.3
-
92
-
-
34547460025
-
Neonatal exposure to bisphenol A modifies the abundance of estrogen receptor alpha transcripts with alternative 5'-untranslated regions in the female rat preoptic area
-
Monje L, Varayoud J, Luque EH, Ramos JG. Neonatal exposure to bisphenol A modifies the abundance of estrogen receptor alpha transcripts with alternative 5'-untranslated regions in the female rat preoptic area. J Endocrinol 2007; 194:201-212.
-
(2007)
J Endocrinol
, vol.194
, pp. 201-212
-
-
Monje, L.1
Varayoud, J.2
Luque, E.H.3
Ramos, J.G.4
-
93
-
-
0141988728
-
Neonatal diethylstilbestrol exposure induces persistent elevation of c-fos expression and hypomethylation in its exon-4 in mouse uterus
-
Li S, Hansman R, Newbold R, Davis B, McLachlan JA, Barrett JC. Neonatal diethylstilbestrol exposure induces persistent elevation of c-fos expression and hypomethylation in its exon-4 in mouse uterus. Mol Carcinog 2003; 38:78-84.
-
(2003)
Mol Carcinog
, vol.38
, pp. 78-84
-
-
Li, S.1
Hansman, R.2
Newbold, R.3
Davis, B.4
McLachlan, J.A.5
Barrett, J.C.6
-
94
-
-
34547117535
-
The developmental origins of health and disease: current theories and epigenetic mechanisms
-
Sinclair KD, Lea RG, Rees WD, Young LE. The developmental origins of health and disease: current theories and epigenetic mechanisms. Soc Reprod Fertil Suppl 2007; 64:425-443.
-
(2007)
Soc Reprod Fertil Suppl
, vol.64
, pp. 425-443
-
-
Sinclair, K.D.1
Lea, R.G.2
Rees, W.D.3
Young, L.E.4
-
95
-
-
34247473478
-
The epigenetic basis of twin discordance in age-related diseases
-
Poulsen P, Esteller M, Vaag A, Fraga MF. The epigenetic basis of twin discordance in age-related diseases. Pediatr Res 2007; 61:38R-42R.
-
(2007)
Pediatr Res
, vol.61
, pp. 38R-42R
-
-
Poulsen, P.1
Esteller, M.2
Vaag, A.3
Fraga, M.F.4
-
96
-
-
23044514669
-
Epigenetic differences arise during the lifetime of monozygotic twins
-
Fraga MF, Ballestar E, Paz MF, et al. Epigenetic differences arise during the lifetime of monozygotic twins. Proc Natl Acad Sci USA 2005; 102:10604-10609.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 10604-10609
-
-
Fraga, M.F.1
Ballestar, E.2
Paz, M.F.3
-
97
-
-
34250617919
-
Cancer susceptibility: epigenetic manifestation of environmental exposures
-
Weidman JR, Dolinoy DC, Murphy SK, Jirtle RL. Cancer susceptibility: epigenetic manifestation of environmental exposures. Cancer J 2007; 13:9-16.
-
(2007)
Cancer J
, vol.13
, pp. 9-16
-
-
Weidman, J.R.1
Dolinoy, D.C.2
Murphy, S.K.3
Jirtle, R.L.4
-
98
-
-
35349006389
-
RNA interference-about the reality to be exploited in cancer therapy
-
Bakalova R. RNA interference-about the reality to be exploited in cancer therapy. Methods Find Exp Clin Pharmacol 2007; 29:417-421.
-
(2007)
Methods Find Exp Clin Pharmacol
, vol.29
, pp. 417-421
-
-
Bakalova, R.1
-
99
-
-
35949000503
-
Small interfering RNA (siRNA) inhibited human liver cancer cell line SMMC7721 proliferation and tumorigenesis
-
Dong-Dong L. Small interfering RNA (siRNA) inhibited human liver cancer cell line SMMC7721 proliferation and tumorigenesis. Hepatogastroenterology 2007; 54:1731-1735.
-
(2007)
Hepatogastroenterology
, vol.54
, pp. 1731-1735
-
-
Dong-dong, L.1
-
100
-
-
37149024397
-
Growth inhibition of breast cancer cell line MCF-7 by siRNA silencing of Wilms tumor 1 gene
-
Navakanit R, Graidist P, Leeanansaksiri W, Dechsukum C. Growth inhibition of breast cancer cell line MCF-7 by siRNA silencing of Wilms tumor 1 gene. J Med Assoc Thai 2007; 90:2416-2421.
-
(2007)
J Med Assoc Thai
, vol.90
, pp. 2416-2421
-
-
Navakanit, R.1
Graidist, P.2
Leeanansaksiri, W.3
Dechsukum, C.4
-
101
-
-
35449003175
-
MicroRNA let-7a down-regulates MYC and reverts MYC-induced growth in Burkitt lymphoma cells
-
Sampson VB, Rong NH, Han J, et al. MicroRNA let-7a down-regulates MYC and reverts MYC-induced growth in Burkitt lymphoma cells. Cancer Res 2007; 67:9762-9770.
-
(2007)
Cancer Res
, vol.67
, pp. 9762-9770
-
-
Sampson, V.B.1
Rong, N.H.2
Han, J.3
-
102
-
-
29244457579
-
A blueprint for a Human Epigenome Project: the AACR Human Epigenome Workshop
-
Jones PA, Martienssen R. A blueprint for a Human Epigenome Project: the AACR Human Epigenome Workshop. Cancer Res 2005; 65:11241-11246.
-
(2005)
Cancer Res
, vol.65
, pp. 11241-11246
-
-
Jones, P.A.1
Martienssen, R.2
-
103
-
-
34249793251
-
Histone acetylation and methylation: combinatorial players for transcriptional regulation
-
An W. Histone acetylation and methylation: combinatorial players for transcriptional regulation. Subcell Biochem 2007; 41:351-369.
-
(2007)
Subcell Biochem
, vol.41
, pp. 351-369
-
-
An, W.1
-
104
-
-
33846122993
-
Dimethyl sulfoxide to vorinostat: development of this histone deacetylase inhibitor as an anticancer drug
-
Marks PA, Breslow R. Dimethyl sulfoxide to vorinostat: development of this histone deacetylase inhibitor as an anticancer drug. Nat Biotechnol 2007; 25:84-90.
-
(2007)
Nat Biotechnol
, vol.25
, pp. 84-90
-
-
Marks, P.A.1
Breslow, R.2
-
105
-
-
43249120953
-
Histone deacetylase inhibitors: mechanisms and clinical significance in cancer: HDAC inhibitor-induced apoptosis
-
Shankar S, Srivastava RK. Histone deacetylase inhibitors: mechanisms and clinical significance in cancer: HDAC inhibitor-induced apoptosis. Adv Exp Med Biol 2008; 615:261-298.
-
(2008)
Adv Exp Med Biol
, vol.615
, pp. 261-298
-
-
Shankar, S.1
Srivastava, R.K.2
-
106
-
-
36849090114
-
Epigenetic regulation: a new research area for melatonin?
-
Korkmaz A, Reiter RJ. Epigenetic regulation: a new research area for melatonin? J Pineal Res 2008; 44:41-44.
-
(2008)
J Pineal Res
, vol.44
, pp. 41-44
-
-
Korkmaz, A.1
Reiter, R.J.2
-
107
-
-
36048958965
-
Histone deacetylase inhibitors: overview and perspectives
-
Dokmanovic M, Clarke C, Marks PA. Histone deacetylase inhibitors: overview and perspectives. Mol Cancer Res 2007; 5:981-989.
-
(2007)
Mol Cancer Res
, vol.5
, pp. 981-989
-
-
Dokmanovic, M.1
Clarke, C.2
Marks, P.A.3
-
108
-
-
33846261713
-
Histone deacetylase inhibitors for cancer therapy
-
Kim TY, Bang YJ, Robertson KD. Histone deacetylase inhibitors for cancer therapy. Epigenetics 2006; 1:14-23.
-
(2006)
Epigenetics
, vol.1
, pp. 14-23
-
-
Kim, T.Y.1
Bang, Y.J.2
Robertson, K.D.3
-
109
-
-
33847786883
-
A proof-of-principle study of epigenetic therapy added to neoadjuvant doxorubicin cyclophosphamide for locally advanced breast cancer
-
Arce C, Perez-Plasencia C, Gonzalez-Fierro A, et al. A proof-of-principle study of epigenetic therapy added to neoadjuvant doxorubicin cyclophosphamide for locally advanced breast cancer. PLoS ONE 2006; 1:e98.
-
(2006)
PLoS ONE
, vol.1
, pp. e98
-
-
Arce, C.1
Perez-plasencia, C.2
Gonzalez-fierro, A.3
-
110
-
-
38849203044
-
Epigenetic regulation of RhoB loss of expression in lung cancer
-
Mazieres J, Tovar D, He B, et al. Epigenetic regulation of RhoB loss of expression in lung cancer. BMC Cancer 2007; 7:220.
-
(2007)
BMC Cancer
, vol.7
, pp. 220
-
-
Mazieres, J.1
Tovar, D.2
He, B.3
-
111
-
-
31344446955
-
Combination therapy with DNA methyltransferase inhibitors in hematologic malignancies
-
Gore SD. Combination therapy with DNA methyltransferase inhibitors in hematologic malignancies. Nat Clin Pract 2005; 2(Suppl 1):S30-S35.
-
(2005)
Nat Clin Pract
, vol.2
, pp. S30-S35
-
-
Gore, S.D.1
-
112
-
-
20444479514
-
Drug insight: Histone deacetylase inhibitors-development of the new targeted anticancer agent suberoylanilide hydroxamic acid
-
Kelly WK, Marks PA. Drug insight: Histone deacetylase inhibitors-development of the new targeted anticancer agent suberoylanilide hydroxamic acid. Nat Clin Pract 2005; 2:150-157.
-
(2005)
Nat Clin Pract
, vol.2
, pp. 150-157
-
-
Kelly, W.K.1
Marks, P.A.2
-
113
-
-
3042785975
-
A review of depsipeptide and other histone deacetylase inhibitors in clinical trials
-
Piekarz R, Bates S. A review of depsipeptide and other histone deacetylase inhibitors in clinical trials. Curr Pharm Des 2004; 10:2289-2298.
-
(2004)
Curr Pharm Des
, vol.10
, pp. 2289-2298
-
-
Piekarz, R.1
Bates, S.2
-
114
-
-
34250651294
-
Histone deacetylase inhibitors and demethylating agents: clinical development of histone deacetylase inhibitors for cancer therapy
-
Piekarz RL, Sackett DL, Bates SE. Histone deacetylase inhibitors and demethylating agents: clinical development of histone deacetylase inhibitors for cancer therapy. Cancer J 2007; 13:30-39.
-
(2007)
Cancer J
, vol.13
, pp. 30-39
-
-
Piekarz, R.L.1
Sackett, D.L.2
Bates, S.E.3
-
115
-
-
33144481148
-
Protein lysine acetylation in normal and leukaemic haematopoiesis: HDACs as possible therapeutic targets in adult AML
-
Bruserud O, Stapnes C, Tronstad KJ, Ryningen A, Anensen N, Gjertsen BT. Protein lysine acetylation in normal and leukaemic haematopoiesis: HDACs as possible therapeutic targets in adult AML. Expert Opin Ther Targets 2006; 10:51-68.
-
(2006)
Expert Opin Ther Targets
, vol.10
, pp. 51-68
-
-
Bruserud, O.1
Stapnes, C.2
Tronstad, K.J.3
Ryningen, A.4
Anensen, N.5
Gjertsen, B.T.6
-
116
-
-
33845514708
-
Will broad-spectrum histone deacetylase inhibitors be superseded by more specific compounds?
-
Karagiannis TC, El-Osta A. Will broad-spectrum histone deacetylase inhibitors be superseded by more specific compounds? Leukemia 2007; 21:61-65.
-
(2007)
Leukemia
, vol.21
, pp. 61-65
-
-
Karagiannis, T.C.1
El-osta, A.2
-
117
-
-
33747203758
-
Antileukemia activity of the combination of an anthracycline with a histone deacetylase inhibitor
-
Sanchez-Gonzalez B, Yang H, Bueso-Ramos C, et al. Antileukemia activity of the combination of an anthracycline with a histone deacetylase inhibitor. Blood 2006; 108:1174-1182.
-
(2006)
Blood
, vol.108
, pp. 1174-1182
-
-
Sanchez-gonzalez, B.1
Yang, H.2
Bueso-ramos, C.3
-
118
-
-
33750463070
-
Cytotoxic effects of histone deacetylase inhibitor FK228 (depsipeptide, formally named FR901228) in combination with conventional anti-leukemia/lymphoma agents against human leukemia/lymphoma cell lines
-
Kano Y, Akutsu M, Tsunoda S, et al. Cytotoxic effects of histone deacetylase inhibitor FK228 (depsipeptide, formally named FR901228) in combination with conventional anti-leukemia/lymphoma agents against human leukemia/lymphoma cell lines. Invest New Drugs 2007; 25:31-40.
-
(2007)
Invest New Drugs
, vol.25
, pp. 31-40
-
-
Kano, Y.1
Akutsu, M.2
Tsunoda, S.3
-
119
-
-
33746917919
-
Bortezomib and depsipeptide sensitize tumors to tumor necrosis factor-related apoptosis-inducing ligand: a novel method to potentiate natural killer cell tumor cytotoxicity
-
Lundqvist A, Abrams SI, Schrump DS, et al. Bortezomib and depsipeptide sensitize tumors to tumor necrosis factor-related apoptosis-inducing ligand: a novel method to potentiate natural killer cell tumor cytotoxicity. Cancer Res 2006; 66:7317-7325.
-
(2006)
Cancer Res
, vol.66
, pp. 7317-7325
-
-
Lundqvist, A.1
Abrams, S.I.2
Schrump, D.S.3
-
120
-
-
33745895281
-
The histone deacetylase inhibitor, suberoylanilide hydroxamic acid, overcomes resistance of human breast cancer cells to Apo2L/TRAIL
-
Butler LM, Liapis V, Bouralexis S, et al. The histone deacetylase inhibitor, suberoylanilide hydroxamic acid, overcomes resistance of human breast cancer cells to Apo2L/TRAIL. Int J Cancer 2006; 119:944-954.
-
(2006)
Int J Cancer
, vol.119
, pp. 944-954
-
-
Butler, L.M.1
Liapis, V.2
Bouralexis, S.3
-
121
-
-
33745280074
-
Synergistic induction of folate receptor beta by all-trans retinoic acid and histone deacetylase inhibitors in acute myelogenous leukemia cells: mechanism and utility in enhancing selective growth inhibition by antifolates
-
Qi H, Ratnam M. Synergistic induction of folate receptor beta by all-trans retinoic acid and histone deacetylase inhibitors in acute myelogenous leukemia cells: mechanism and utility in enhancing selective growth inhibition by antifolates. Cancer Res 2006; 66:5875-5882.
-
(2006)
Cancer Res
, vol.66
, pp. 5875-5882
-
-
Qi, H.1
Ratnam, M.2
-
122
-
-
7244221565
-
Purchase of Aton spotlights HDAC inhibitors
-
Garber K. Purchase of Aton spotlights HDAC inhibitors. Nat Biotechnol 2004; 22:364-365.
-
(2004)
Nat Biotechnol
, vol.22
, pp. 364-365
-
-
Garber, K.1
-
123
-
-
33745629366
-
Gemcitabine plus CI-994 offers no advantage over gemcitabine alone in the treatment of patients with advanced pancreatic cancer: results of a phase II randomized, double-blind, placebo-controlled, multicenter study
-
Richards DA, Boehm KA, Waterhouse DM, et al. Gemcitabine plus CI-994 offers no advantage over gemcitabine alone in the treatment of patients with advanced pancreatic cancer: results of a phase II randomized, double-blind, placebo-controlled, multicenter study. Ann Oncol 2006; 17:1096-1102.
-
(2006)
Ann Oncol
, vol.17
, pp. 1096-1102
-
-
Richards, D.A.1
Boehm, K.A.2
Waterhouse, D.M.3
-
124
-
-
16344391638
-
In vitro study of CI-994, a histone deacetylase inhibitor, in non-small cell lung cancer cell lines
-
Loprevite M, Tiseo M, Grossi F, et al. In vitro study of CI-994, a histone deacetylase inhibitor, in non-small cell lung cancer cell lines. Oncol Res 2005; 15:39-48.
-
(2005)
Oncol Res
, vol.15
, pp. 39-48
-
-
Loprevite, M.1
Tiseo, M.2
Grossi, F.3
-
125
-
-
29144484694
-
Clinical trial of valproic acid and all-trans retinoic acid in patients with poor-risk acute myeloid leukemia
-
Bug G, Ritter M, Wassmann B, et al. Clinical trial of valproic acid and all-trans retinoic acid in patients with poor-risk acute myeloid leukemia. Cancer 2005; 104:2717-2725.
-
(2005)
Cancer
, vol.104
, pp. 2717-2725
-
-
Bug, G.1
Ritter, M.2
Wassmann, B.3
-
126
-
-
34547663854
-
Effect of histone deacetylase inhibitor valproic acid on progenitor cells of acute myeloid leukemia
-
Bug G, Schwarz K, Schoch C, et al. Effect of histone deacetylase inhibitor valproic acid on progenitor cells of acute myeloid leukemia. Haematologica 2007; 92:542-545.
-
(2007)
Haematologica
, vol.92
, pp. 542-545
-
-
Bug, G.1
Schwarz, K.2
Schoch, C.3
-
127
-
-
0037420191
-
Inhibition of DNA methylation and reactivation of silenced genes by zebularine
-
Cheng JC, Matsen CB, Gonzales FA, et al. Inhibition of DNA methylation and reactivation of silenced genes by zebularine. J Natl Cancer Inst 2003; 95:399-409.
-
(2003)
J Natl Cancer Inst
, vol.95
, pp. 399-409
-
-
Cheng, J.C.1
Matsen, C.B.2
Gonzales, F.A.3
-
128
-
-
4544242851
-
Induction of DNA methylation and gene silencing by short interfering RNAs in human cells
-
Kawasaki H, Taira K. Induction of DNA methylation and gene silencing by short interfering RNAs in human cells. Nature 2004; 431:211-217.
-
(2004)
Nature
, vol.431
, pp. 211-217
-
-
Kawasaki, H.1
Taira, K.2
-
129
-
-
41349113351
-
Promoter analysis of epigenetically controlled genes in bladder cancer
-
Veerla S, Panagopoulos I, Jin Y, Lindgren D, Hoglund M. Promoter analysis of epigenetically controlled genes in bladder cancer. Genes Chromosomes Cancer 2008; 47:368-378.
-
(2008)
Genes Chromosomes Cancer
, vol.47
, pp. 368-378
-
-
Veerla, S.1
Panagopoulos, I.2
Jin, Y.3
Lindgren, D.4
Hoglund, M.5
-
130
-
-
36749086010
-
Epigenetic aberrations in malignant gliomas: an open door leading to better understanding and treatment
-
Martinez R, Schackert G. Epigenetic aberrations in malignant gliomas: an open door leading to better understanding and treatment. Epigenetics 2007; 2:147-150.
-
(2007)
Epigenetics
, vol.2
, pp. 147-150
-
-
Martinez, R.1
Schackert, G.2
-
131
-
-
33846009775
-
MGMT methylation: a marker of response to temozolomide in low-grade gliomas
-
Everhard S, Kaloshi G, Criniere E, et al. MGMT methylation: a marker of response to temozolomide in low-grade gliomas. Ann Neurol 2006; 60:740-743.
-
(2006)
Ann Neurol
, vol.60
, pp. 740-743
-
-
Everhard, S.1
Kaloshi, G.2
Criniere, E.3
-
132
-
-
44849114690
-
BRCA1 promoter methylation in peripheral blood DNA of mutation negative familial breast cancer patients with a BRCA1 tumour phenotype
-
Snell C, Krypuy M, Wong EM, Loughrey MB, Dobrovic A. BRCA1 promoter methylation in peripheral blood DNA of mutation negative familial breast cancer patients with a BRCA1 tumour phenotype. Breast Cancer Res 2008; 10:R12.
-
(2008)
Breast Cancer Res
, vol.10
, pp. R12
-
-
Snell, C.1
Krypuy, M.2
Wong, E.M.3
Loughrey, M.B.4
Dobrovic, A.5
-
133
-
-
36148945223
-
Downregulation of the RUNX3 gene by promoter hypermethylation and hemizygous deletion in breast cancer
-
Hwang KT, Han W, Bae JY, et al. Downregulation of the RUNX3 gene by promoter hypermethylation and hemizygous deletion in breast cancer. J Korean Med Sci 2007; 22(Suppl):S24-S31.
-
(2007)
J Korean Med Sci
, vol.22
, Issue.SUPPL
, pp. S24-S31
-
-
Hwang, K.T.1
Han, W.2
Bae, J.Y.3
-
134
-
-
39849096261
-
Epigenetic silencing of CXCL12 increases the metastatic potential of mammary carcinoma cells
-
Wendt MK, Cooper AN, Dwinell MB. Epigenetic silencing of CXCL12 increases the metastatic potential of mammary carcinoma cells. Oncogene 2008; 27:1461-1471.
-
(2008)
Oncogene
, vol.27
, pp. 1461-1471
-
-
Wendt, M.K.1
Cooper, A.N.2
Dwinell, M.B.3
-
135
-
-
34447100205
-
Promoter hypermethylation of TMS1, BRCA1, ERalpha and PRB in serum and tumor DNA of invasive ductal breast carcinoma patients
-
Mirza S, Sharma G, Prasad CP, et al. Promoter hypermethylation of TMS1, BRCA1, ERalpha and PRB in serum and tumor DNA of invasive ductal breast carcinoma patients. Life Sci 2007; 81:280-287.
-
(2007)
Life Sci
, vol.81
, pp. 280-287
-
-
Mirza, S.1
Sharma, G.2
Prasad, C.P.3
-
136
-
-
34250891865
-
Epigenetic silencing of the candidate tumor suppressor gene PROX1 in sporadic breast cancer
-
Versmold B, Felsberg J, Mikeska T, et al. Epigenetic silencing of the candidate tumor suppressor gene PROX1 in sporadic breast cancer. Int J Cancer 2007; 121:547-554.
-
(2007)
Int J Cancer
, vol.121
, pp. 547-554
-
-
Versmold, B.1
Felsberg, J.2
Mikeska, T.3
-
137
-
-
34147134560
-
Promoter hypermethylation of p16INK4A, p14ARF, CyclinD2 and Slit2 in serum and tumor DNA from breast cancer patients
-
Sharma G, Mirza S, Prasad CP, Srivastava A, Gupta SD, Ralhan R. Promoter hypermethylation of p16INK4A, p14ARF, CyclinD2 and Slit2 in serum and tumor DNA from breast cancer patients. Life Sci 2007; 80:1873-1881.
-
(2007)
Life Sci
, vol.80
, pp. 1873-1881
-
-
Sharma, G.1
Mirza, S.2
Prasad, C.P.3
Srivastava, A.4
Gupta, S.D.5
Ralhan, R.6
-
138
-
-
33847696486
-
Role of physical activity in modulating breast cancer risk as defined by APC and RASSF1A promoter hypermethylation in nonmalignant breast tissue
-
Coyle YM, Xie XJ, Lewis CM, Bu D, Milchgrub S, Euhus DM. Role of physical activity in modulating breast cancer risk as defined by APC and RASSF1A promoter hypermethylation in nonmalignant breast tissue. Cancer Epidemiol Biomarkers Prev 2007; 16:192-196.
-
(2007)
Cancer Epidemiol Biomarkers Prev
, vol.16
, pp. 192-196
-
-
Coyle, Y.M.1
Xie, X.J.2
Lewis, C.M.3
Bu, D.4
Milchgrub, S.5
Euhus, D.M.6
-
139
-
-
34247550919
-
CDH1 promoter hypermethylation and E-cadherin protein expression in infiltrating breast cancer
-
Caldeira JR, Prando EC, Quevedo FC, Neto FA, Rainho CA, Rogatto SR. CDH1 promoter hypermethylation and E-cadherin protein expression in infiltrating breast cancer. BMC Cancer 2006; 6:48.
-
(2006)
BMC Cancer
, vol.6
, pp. 48
-
-
Caldeira, J.R.1
Prando, E.C.2
Quevedo, F.C.3
Neto, F.A.4
Rainho, C.A.5
Rogatto, S.R.6
-
140
-
-
33646247193
-
Methylation of the IL-12Rbeta2 gene as novel tumor escape mechanism for pediatric B-acute lymphoblastic leukemia cells
-
Airoldi I, Cocco C, Di Carlo E, et al. Methylation of the IL-12Rbeta2 gene as novel tumor escape mechanism for pediatric B-acute lymphoblastic leukemia cells. Cancer Res 2006; 66:3978-3980.
-
(2006)
Cancer Res
, vol.66
, pp. 3978-3980
-
-
Airoldi, I.1
Cocco, C.2
Di Carlo, E.3
-
141
-
-
33749625622
-
APC gene methylation is inversely correlated with features of the CpG island methylator phenotype in colorectal cancer
-
Iacopetta B, Grieu F, Li W, et al. APC gene methylation is inversely correlated with features of the CpG island methylator phenotype in colorectal cancer. Int J Cancer 2006; 119:2272-2278.
-
(2006)
Int J Cancer
, vol.119
, pp. 2272-2278
-
-
Iacopetta, B.1
Grieu, F.2
Li, W.3
-
142
-
-
10744230172
-
Extensive but hemiallelic methylation of the hMLH1 promoter region in early-onset sporadic colon cancers with microsatellite instability
-
Miyakura Y, Sugano K, Akasu T, et al. Extensive but hemiallelic methylation of the hMLH1 promoter region in early-onset sporadic colon cancers with microsatellite instability. Clin Gastroenterol Hepatol 2004; 2:147-156.
-
(2004)
Clin Gastroenterol Hepatol
, vol.2
, pp. 147-156
-
-
Miyakura, Y.1
Sugano, K.2
Akasu, T.3
-
143
-
-
34249782843
-
Differential methylation hybridization array of endometrial cancers reveals two novel cancer-specific methylation markers
-
Zighelboim I, Goodfellow PJ, Schmidt AP, et al. Differential methylation hybridization array of endometrial cancers reveals two novel cancer-specific methylation markers. Clin Cancer Res 2007; 13:2882-2889.
-
(2007)
Clin Cancer Res
, vol.13
, pp. 2882-2889
-
-
Zighelboim, I.1
Goodfellow, P.J.2
Schmidt, A.P.3
-
144
-
-
61349104367
-
Progressive silencing of p14ARF in oesophageal adenocarcinoma
-
February
-
Huang Y, Peters CJ, Fitzgerald RC, Gjerset RA. Progressive silencing of p14ARF in oesophageal adenocarcinoma. J Cell Mol Med February 2008; 13 (2):398-409.
-
(2008)
J Cell Mol Med
, vol.13
, Issue.2
, pp. 398-409
-
-
Huang, Y.1
Peters, C.J.2
Fitzgerald, R.C.3
Gjerset, R.A.4
-
145
-
-
34147221687
-
Association between Helicobacter pylori infection and interleukin 1beta polymorphism predispose to CpG island methylation in gastric cancer
-
Chan AO, Chu KM, Huang C, et al. Association between Helicobacter pylori infection and interleukin 1beta polymorphism predispose to CpG island methylation in gastric cancer. Gut 2007; 56:595-597.
-
(2007)
Gut
, vol.56
, pp. 595-597
-
-
Chan, A.O.1
Chu, K.M.2
Huang, C.3
-
146
-
-
23844517119
-
Diagnostic and therapeutic applications of epigenetics
-
Miyamoto K, Ushijima T. Diagnostic and therapeutic applications of epigenetics. Jpn J Clin Oncol 2005; 35:293-301.
-
(2005)
Jpn J Clin Oncol
, vol.35
, pp. 293-301
-
-
Miyamoto, K.1
Ushijima, T.2
-
147
-
-
34548090762
-
Differential DNA methylation associated with hepatitis B virus infection in hepatocellular carcinoma
-
Su PF, Lee TC, Lin PJ, et al. Differential DNA methylation associated with hepatitis B virus infection in hepatocellular carcinoma. Int J Cancer 2007; 121:1257-1264.
-
(2007)
Int J Cancer
, vol.121
, pp. 1257-1264
-
-
Su, P.F.1
Lee, T.C.2
Lin, P.J.3
-
148
-
-
41549108332
-
DNA methylation in tumor and matched normal tissues from non-small cell lung cancer patients
-
Feng Q, Hawes SE, Stern JE, et al. DNA methylation in tumor and matched normal tissues from non-small cell lung cancer patients. Cancer Epidemiol Biomarkers Prev 2008; 17:645-654.
-
(2008)
Cancer Epidemiol Biomarkers Prev
, vol.17
, pp. 645-654
-
-
Feng, Q.1
Hawes, S.E.2
Stern, J.E.3
-
149
-
-
0036433743
-
Genetic and epigenetic changes in nasopharyngeal carcinoma
-
Lo KW, Huang DP. Genetic and epigenetic changes in nasopharyngeal carcinoma. Semin Cancer Biol 2002; 12:451-462.
-
(2002)
Semin Cancer Biol
, vol.12
, pp. 451-462
-
-
Lo, K.W.1
Huang, D.P.2
-
150
-
-
33845611987
-
Discovery of novel epigenetic markers in non-Hodgkin's lymphoma
-
Shi H, Guo J, Duff DJ, et al. Discovery of novel epigenetic markers in non-Hodgkin's lymphoma. Carcinogenesis 2007; 28:60-70.
-
(2007)
Carcinogenesis
, vol.28
, pp. 60-70
-
-
Shi, H.1
Guo, J.2
Duff, D.J.3
-
151
-
-
42149144580
-
Promoter hypermethylation of FANCF and outcome in advanced ovarian cancer
-
Lim SL, Smith P, Syed N, et al. Promoter hypermethylation of FANCF and outcome in advanced ovarian cancer. Br J Cancer 2008; 98:1452-1456.
-
(2008)
Br J Cancer
, vol.98
, pp. 1452-1456
-
-
Lim, S.L.1
Smith, P.2
Syed, N.3
-
152
-
-
33745871210
-
Aberrant promoter methylation of multiple genes in malignant ovarian tumors and in ovarian tumors with low malignant potential
-
Wiley A, Katsaros D, Chen H, et al. Aberrant promoter methylation of multiple genes in malignant ovarian tumors and in ovarian tumors with low malignant potential. Cancer 2006; 107:299-308.
-
(2006)
Cancer
, vol.107
, pp. 299-308
-
-
Wiley, A.1
Katsaros, D.2
Chen, H.3
-
153
-
-
33947726956
-
Methylation status of the SOCS3 gene in human malignant melanomas
-
Tokita T, Maesawa C, Kimura T, et al. Methylation status of the SOCS3 gene in human malignant melanomas. Int J Oncol 2007; 30:689-694.
-
(2007)
Int J Oncol
, vol.30
, pp. 689-694
-
-
Tokita, T.1
Maesawa, C.2
Kimura, T.3
-
154
-
-
33749850969
-
Epigenetic abnormalities in cutaneous squamous cell carcinomas: frequent inactivation of the RB1/p16 and p53 pathways
-
Murao K, Kubo Y, Ohtani N, Hara E, Arase S. Epigenetic abnormalities in cutaneous squamous cell carcinomas: frequent inactivation of the RB1/p16 and p53 pathways. Br J Dermatol 2006; 155:999-1005.
-
(2006)
Br J Dermatol
, vol.155
, pp. 999-1005
-
-
Murao, K.1
Kubo, Y.2
Ohtani, N.3
Hara, E.4
Arase, S.5
-
155
-
-
21244458051
-
Epigenetic profiling of cutaneous T-cell lymphoma: promoter hypermethylation of multiple tumor suppressor genes including BCL7a, PTPRG, and p73
-
van Doorn R, Zoutman WH, Dijkman R, et al. Epigenetic profiling of cutaneous T-cell lymphoma: promoter hypermethylation of multiple tumor suppressor genes including BCL7a, PTPRG, and p73. J Clin Oncol 2005; 23:3886-3896.
-
(2005)
J Clin Oncol
, vol.23
, pp. 3886-3896
-
-
van Doorn, R.1
Zoutman, W.H.2
Dijkman, R.3
-
156
-
-
2542522279
-
Profiling epigenetic inactivation of tumor suppressor genes in tumors and plasma from cutaneous melanoma patients
-
Hoon DS, Spugnardi M, Kuo C, Huang SK, Morton DL, Taback B. Profiling epigenetic inactivation of tumor suppressor genes in tumors and plasma from cutaneous melanoma patients. Oncogene 2004; 23:4014-4022.
-
(2004)
Oncogene
, vol.23
, pp. 4014-4022
-
-
Hoon, D.S.1
Spugnardi, M.2
Kuo, C.3
Huang, S.K.4
Morton, D.L.5
Taback, B.6
-
157
-
-
21544483241
-
Methylation of the tumor suppressor gene RASSF1A in human tumors
-
Pfeifer GP, Dammann R. Methylation of the tumor suppressor gene RASSF1A in human tumors. Biochemistry (Mosc) 2005; 70:576-583.
-
(2005)
Biochemistry (Mosc)
, vol.70
, pp. 576-583
-
-
Pfeifer, G.P.1
Dammann, R.2
-
158
-
-
0034650338
-
Mechanism for inactivation of the KIP family cyclin-dependent kinase inhibitor genes in gastric cancer cells
-
Shin JY, Kim HS, Park J, Park JB, Lee JY. Mechanism for inactivation of the KIP family cyclin-dependent kinase inhibitor genes in gastric cancer cells. Cancer Res 2000; 60:262-265.
-
(2000)
Cancer Res
, vol.60
, pp. 262-265
-
-
Shin, J.Y.1
Kim, H.S.2
Park, J.3
Park, J.B.4
Lee, J.Y.5
-
159
-
-
1642499364
-
Continuous zebularine treatment effectively sustains demethylation in human bladder cancer cells
-
Cheng JC, Weisenberger DJ, Gonzales FA, et al. Continuous zebularine treatment effectively sustains demethylation in human bladder cancer cells. Mol Cell Biol 2004; 24:1270-1278.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 1270-1278
-
-
Cheng, J.C.1
Weisenberger, D.J.2
Gonzales, F.A.3
-
160
-
-
26644460450
-
Zebularine: a unique molecule for an epigenetically based strategy in cancer chemotherapy. The magic of its chemistry and biology
-
Marquez VE, Barchi JJ, Jr, Kelley JA, et al. Zebularine: a unique molecule for an epigenetically based strategy in cancer chemotherapy. The magic of its chemistry and biology. Nucleosides Nucleotides Nucleic Acids 2005; 24:305-318.
-
(2005)
Nucleosides Nucleotides Nucleic Acids
, vol.24
, pp. 305-318
-
-
Marquez, V.E.1
Barchi Jr., J.J.2
Kelley, J.A.3
-
161
-
-
33748451151
-
Anticancer activities of histone deacetylase inhibitors
-
Bolden JE, Peart MJ, Johnstone RW. Anticancer activities of histone deacetylase inhibitors. Nature Rev 2006; 5:769-784.
-
(2006)
Nature Rev
, vol.5
, pp. 769-784
-
-
Bolden, J.E.1
Peart, M.J.2
Johnstone, R.W.3
-
162
-
-
33750514048
-
5-Aza-2'-deoxycytidine and depsipeptide synergistically induce expression of BIK (BCL2-interacting killer)
-
Dai Z, Liu S, Marcucci G, Sadee W. 5-Aza-2'-deoxycytidine and depsipeptide synergistically induce expression of BIK (BCL2-interacting killer). Biochem Biophys Res Commun 2006; 351:455-461.
-
(2006)
Biochem Biophys Res Commun
, vol.351
, pp. 455-461
-
-
Dai, Z.1
Liu, S.2
Marcucci, G.3
Sadee, W.4
-
163
-
-
0033577058
-
Molecular detection of tumor cells in bronchoalveolar lavage fluid from patients with early stage lung cancer
-
Ahrendt SA, Chow JT, Xu LH, et al. Molecular detection of tumor cells in bronchoalveolar lavage fluid from patients with early stage lung cancer. J Natl Cancer Inst 1999; 91:332-339.
-
(1999)
J Natl Cancer Inst
, vol.91
, pp. 332-339
-
-
Ahrendt, S.A.1
Chow, J.T.2
Xu, L.H.3
-
164
-
-
23744513863
-
Smokeless tobacco (khaini) extracts modulate gene expression in epithelial cell culture from an oral hyperplasia
-
Rohatgi N, Kaur J, Srivastava A, Ralhan R. Smokeless tobacco (khaini) extracts modulate gene expression in epithelial cell culture from an oral hyperplasia. Oral Oncol 2005; 41:806-820.
-
(2005)
Oral Oncol
, vol.41
, pp. 806-820
-
-
Rohatgi, N.1
Kaur, J.2
Srivastava, A.3
Ralhan, R.4
-
165
-
-
0142059070
-
Aberrant methylation of the cyclin D2 promoter in primary small cell, nonsmall cell lung and breast cancers
-
Virmani A, Rathi A, Heda S, et al. Aberrant methylation of the cyclin D2 promoter in primary small cell, nonsmall cell lung and breast cancers. Int J Cancer 2003; 107:341-345.
-
(2003)
Int J Cancer
, vol.107
, pp. 341-345
-
-
Virmani, A.1
Rathi, A.2
Heda, S.3
-
166
-
-
2042503039
-
Adding HPV16 testing to abnormal cervical smear detection is useful for predicting CIN3: a prospective study
-
Tanaka H, Sato H, Sato N, et al. Adding HPV16 testing to abnormal cervical smear detection is useful for predicting CIN3: a prospective study. Acta Obstet Gynecol Scand 2004; 83:497-500.
-
(2004)
Acta Obstet Gynecol Scand
, vol.83
, pp. 497-500
-
-
Tanaka, H.1
Sato, H.2
Sato, N.3
-
167
-
-
0043207664
-
Detection of human papillomavirus DNA in self-administered vaginal swabs as compared to cervical swabs
-
Palmisano ME, Gaffga AM, Daigle J, et al. Detection of human papillomavirus DNA in self-administered vaginal swabs as compared to cervical swabs. International journal of STD & AIDS 2003; 14:560-567.
-
(2003)
International journal of STD & AIDS
, vol.14
, pp. 560-567
-
-
Palmisano, M.E.1
Gaffga, A.M.2
Daigle, J.3
-
168
-
-
10744226784
-
Molecular detection of noninvasive and invasive bladder tumor tissues and exfoliated cells by aberrant promoter methylation of laminin-5 encoding genes
-
Sathyanarayana UG, Maruyama R, Padar A, et al. Molecular detection of noninvasive and invasive bladder tumor tissues and exfoliated cells by aberrant promoter methylation of laminin-5 encoding genes. Cancer Res 2004; 64:1425-1430.
-
(2004)
Cancer Res
, vol.64
, pp. 1425-1430
-
-
Sathyanarayana, U.G.1
Maruyama, R.2
Padar, A.3
-
169
-
-
42049110756
-
Identification of novel methylation markers in cervical cancer using restriction landmark genomic scanning
-
Wang SS, Smiraglia DJ, Wu YZ, et al. Identification of novel methylation markers in cervical cancer using restriction landmark genomic scanning. Cancer Res 2008; 68:2489-2497.
-
(2008)
Cancer Res
, vol.68
, pp. 2489-2497
-
-
Wang, S.S.1
Smiraglia, D.J.2
Wu, Y.Z.3
-
170
-
-
40149083881
-
Endogastric capsule for E-cadherin gene (CDH1) promoter hypermethylation assessment in DNA from gastric juice of diffuse gastric cancer patients
-
Muretto P, Ruzzo A, Pizzagalli F, et al. Endogastric capsule for E-cadherin gene (CDH1) promoter hypermethylation assessment in DNA from gastric juice of diffuse gastric cancer patients. Ann Oncol 2008; 19:516-519.
-
(2008)
Ann Oncol
, vol.19
, pp. 516-519
-
-
Muretto, P.1
Ruzzo, A.2
Pizzagalli, F.3
-
171
-
-
0035116695
-
Promoter hypermethylation patterns of p16, O6-methylguanine-DNA-methyltransferase, and death-associated protein kinase in tumors and saliva of head and neck cancer patients
-
Rosas SL, Koch W, da Costa Carvalho MG, et al. Promoter hypermethylation patterns of p16, O6-methylguanine-DNA-methyltransferase, and death-associated protein kinase in tumors and saliva of head and neck cancer patients. Cancer Res 2001; 61:939-942.
-
(2001)
Cancer Res
, vol.61
, pp. 939-942
-
-
Rosas, S.L.1
Koch, W.2
da Costa Carvalho, M.G.3
-
172
-
-
42349114374
-
Double-strand break damage and associated DNA repair genes predispose smokers to gene methylation
-
Leng S, Stidley CA, Willink R, et al. Double-strand break damage and associated DNA repair genes predispose smokers to gene methylation. Cancer Res 2008; 68:3049-3056.
-
(2008)
Cancer Res
, vol.68
, pp. 3049-3056
-
-
Leng, S.1
Stidley, C.A.2
Willink, R.3
-
173
-
-
0034326238
-
Predicting lung cancer by detecting aberrant promoter methylation in sputum
-
Palmisano WA, Divine KK, Saccomanno G, et al. Predicting lung cancer by detecting aberrant promoter methylation in sputum. Cancer Res 2000; 60:5954-5958.
-
(2000)
Cancer Res
, vol.60
, pp. 5954-5958
-
-
Palmisano, W.A.1
Divine, K.K.2
Saccomanno, G.3
-
174
-
-
33947215566
-
Transcriptomic molecular markers for screening human colon cancer in stool and tissue
-
Ahmed FE, Vos P, iJames S, et al. Transcriptomic molecular markers for screening human colon cancer in stool and tissue. Cancer Genomics Proteomics 2007; 4:1-20.
-
(2007)
Cancer Genomics Proteomics
, vol.4
, pp. 1-20
-
-
Ahmed, F.E.1
Vos, P.2
iJames, S.3
-
175
-
-
0034327356
-
Fluorescent methylation-specific polymerase chain reaction for DNA-based detection of prostate cancer in bodily fluids
-
Goessl C, Krause H, Muller M, et al. Fluorescent methylation-specific polymerase chain reaction for DNA-based detection of prostate cancer in bodily fluids. Cancer Res 2000; 60:5941-5945.
-
(2000)
Cancer Res
, vol.60
, pp. 5941-5945
-
-
Goessl, C.1
Krause, H.2
Muller, M.3
-
176
-
-
3442894720
-
Quantitative detection of promoter hypermethylation of multiple genes in the tumor, urine, and serum DNA of patients with renal cancer
-
Hoque MO, Begum S, Topaloglu O, et al. Quantitative detection of promoter hypermethylation of multiple genes in the tumor, urine, and serum DNA of patients with renal cancer. Cancer Res 2004; 64:5511-5517.
-
(2004)
Cancer Res
, vol.64
, pp. 5511-5517
-
-
Hoque, M.O.1
Begum, S.2
Topaloglu, O.3
-
177
-
-
33646193138
-
Genetic and epigenetic biomarkers in cancer: improving diagnosis, risk assessment, and disease stratification
-
Verma M, Seminara D, Arena FJ, John C, Iwamoto K, Hartmuller V. Genetic and epigenetic biomarkers in cancer: improving diagnosis, risk assessment, and disease stratification. Mol Diagn Ther 2006; 10:1-15.
-
(2006)
Mol Diagn Ther
, vol.10
, pp. 1-15
-
-
Verma, M.1
Seminara, D.2
Arena, F.J.3
John, C.4
Iwamoto, K.5
Hartmuller, V.6
-
178
-
-
20444417778
-
Pancreatic cancer epidemiology
-
Verma M. Pancreatic cancer epidemiology. Technol Cancer Res Treat 2005; 4:295-301.
-
(2005)
Technol Cancer Res Treat
, vol.4
, pp. 295-301
-
-
Verma, M.1
-
179
-
-
0029779274
-
Monitoring of aromatic amine exposures in workers at a chemical plant with a known bladder cancer excess
-
Ward EM, Sabbioni G, DeBord DG, et al. Monitoring of aromatic amine exposures in workers at a chemical plant with a known bladder cancer excess. J Natl Cancer Inst 1996; 88:1046-1052.
-
(1996)
J Natl Cancer Inst
, vol.88
, pp. 1046-1052
-
-
Ward, E.M.1
Sabbioni, G.2
DeBord, D.G.3
-
180
-
-
38649087934
-
Human health effects of air pollution
-
January
-
Kampa M, Castanas E. Human health effects of air pollution. Environ Pollut January 2008; 151 (2):362-367.
-
(2008)
Environ Pollut
, vol.151
, Issue.2
, pp. 362-367
-
-
Kampa, M.1
Castanas, E.2
-
181
-
-
36248944148
-
Spirometry, rapid FEV1 decline, and lung cancer among asbestos exposed heavy smokers
-
Chien JW, Au DH, Barnett MJ, Goodman GE. Spirometry, rapid FEV1 decline, and lung cancer among asbestos exposed heavy smokers. Copd 2007; 4:339-346.
-
(2007)
Copd
, vol.4
, pp. 339-346
-
-
Chien, J.W.1
Au, D.H.2
Barnett, M.J.3
Goodman, G.E.4
-
182
-
-
54449092335
-
Risk of gastrointestinal cancers from inhalation and ingestion of asbestos
-
October
-
Gamble J. Risk of gastrointestinal cancers from inhalation and ingestion of asbestos. Regul Toxicol Pharmacol October 2008; 52(1 Suppl):S124-S153.
-
(2008)
Regul Toxicol Pharmacol
, vol.52
, Issue.1 SUPPL
, pp. S124-S153
-
-
Gamble, J.1
-
183
-
-
33644694733
-
Environmental oestrogens, cosmetics and breast cancer
-
Darbre PD. Environmental oestrogens, cosmetics and breast cancer. Best Pract Res 2006; 20:121-143.
-
(2006)
Best Pract Res
, vol.20
, pp. 121-143
-
-
Darbre, P.D.1
-
184
-
-
38949195955
-
Genetic and epigenetic mechanisms in metal carcinogenesis and cocarcinogenesis: nickel, arsenic, and chromium
-
Salnikow K, Zhitkovich A. Genetic and epigenetic mechanisms in metal carcinogenesis and cocarcinogenesis: nickel, arsenic, and chromium. Chem Res Toxicol 2008; 21:28-44.
-
(2008)
Chem Res Toxicol
, vol.21
, pp. 28-44
-
-
Salnikow, K.1
Zhitkovich, A.2
-
185
-
-
34748826738
-
Environmental exposures and gene regulation in disease etiology
-
Edwards TM, Myers JP. Environmental exposures and gene regulation in disease etiology. Environ Health Perspect 2007; 115:1264-1270.
-
(2007)
Environ Health Perspect
, vol.115
, pp. 1264-1270
-
-
Edwards, T.M.1
Myers, J.P.2
-
186
-
-
33645938310
-
Polychlorinated biphenyls (PCBs): routes of exposure and effects on human health
-
Carpenter DO. Polychlorinated biphenyls (PCBs): routes of exposure and effects on human health. Rev Environ Health 2006; 21:1-23.
-
(2006)
Rev Environ Health
, vol.21
, pp. 1-23
-
-
Carpenter, D.O.1
-
187
-
-
34548715144
-
Maternal nutrient supplementation counteracts bisphenol A-induced DNA hypomethylation in early development
-
Dolinoy DC, Huang D, Jirtle RL. Maternal nutrient supplementation counteracts bisphenol A-induced DNA hypomethylation in early development. Proc Natl Acad Sci USA 2007; 104:13056-13061.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 13056-13061
-
-
Dolinoy, D.C.1
Huang, D.2
Jirtle, R.L.3
-
188
-
-
38049084423
-
Fire fighters, combustion products, and urothelial cancer
-
Golka K, Weistenhofer W. Fire fighters, combustion products, and urothelial cancer. J Toxicol Environ Health 2008; 11:32-44.
-
(2008)
J Toxicol Environ Health
, vol.11
, pp. 32-44
-
-
Golka, K.1
Weistenhofer, W.2
-
189
-
-
33744789211
-
Trichloroethylene: mechanisms of renal toxicity and renal cancer and relevance to risk assessment
-
Lock EA, Reed CJ. Trichloroethylene: mechanisms of renal toxicity and renal cancer and relevance to risk assessment. Toxicol Sci 2006; 91:313-331.
-
(2006)
Toxicol Sci
, vol.91
, pp. 313-331
-
-
Lock, E.A.1
Reed, C.J.2
|